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Lexington

$96+ Cheap flights from South Carolina to Lexington (LEX)

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 4/15. Fares are subject to change and may not be available on all flights or dates of travel.
CHS — LEX
Apr 23 — Apr 301
Thu 4/23
Thu 4/30
1 adult, Economy
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Cheap flight deals from South Carolina to Lexington

Cheapest flights from South Carolina to Lexington
Explore the most affordable flight options available from South Carolina to Lexington. Find the lowest fares from popular airlines and budget airlines, with prices last updated on March 24, 2026.

This Kiwi.com deal was found by Cheapflights users on 3/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 4/19:15 am
CLT
-
LEX
1 stop23h 14m
Multiple Airlines
Thu 4/99:31 am
LEX
-
CLT
1 stop15h 07m
Multiple Airlines
Deal found 3/22$249
This American Airlines deal was found by Cheapflights users on 3/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 9/59:00 am
CLT
-
LEX
Nonstop1h 26m
American Airlines
Sat 9/511:42 am
LEX
-
CLT
1 stop9h 54m
American Airlines
Deal found 3/21$269
This Kiwi.com deal was found by Cheapflights users on 3/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 3/293:30 pm
CAE
-
LEX
1 stop23h 57m
Allegiant Air
Wed 4/85:17 pm
LEX
-
CAE
1 stop21h 52m
Allegiant Air
Deal found 3/22$273
This American Airlines deal was found by Cheapflights users on 3/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 4/236:00 pm
CLT
-
LEX
1 stop16h 31m
American Airlines
Fri 4/2411:42 am
LEX
-
CLT
Nonstop1h 32m
American Airlines
Deal found 3/20$277
This Kiwi.com deal was found by Cheapflights users on 3/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 3/293:30 pm
CAE
-
LEX
1 stop23h 57m
Allegiant Air
Sat 4/1110:52 am
LEX
-
CAE
1 stop28h 17m
Allegiant Air
Deal found 3/22$297
This American Airlines deal was found by Cheapflights users on 3/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 4/306:31 pm
MYR
-
LEX
1 stop5h 21m
American Airlines
Mon 5/46:00 am
LEX
-
MYR
1 stop6h 16m
American Airlines
Deal found 3/22$309
This Kiwi.com deal was found by Cheapflights users on 3/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 5/2210:57 am
CLT
-
LEX
1 stop9h 57m
Multiple Airlines
Wed 5/2712:22 pm
LEX
-
CLT
1 stop21h 40m
Multiple Airlines
Deal found 3/23$320
This Kiwi.com deal was found by Cheapflights users on 3/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 4/19:15 am
CLT
-
LEX
1 stop23h 14m
Multiple Airlines
Mon 4/63:44 pm
LEX
-
CLT
1 stop17h 34m
Multiple Airlines
Deal found 3/23$322
This Kiwi.com deal was found by Cheapflights users on 3/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 5/231:00 pm
CLT
-
LEX
2 stops19h 47m
Multiple Airlines
Wed 5/2712:22 pm
LEX
-
CLT
1 stop21h 40m
Multiple Airlines
Deal found 3/23$324
This Delta deal was found by Cheapflights users on 3/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 10/76:00 am
MYR
-
LEX
1 stop3h 26m
Delta
Sat 10/106:00 am
LEX
-
MYR
1 stop4h 08m
Delta
Deal found 3/19$325
This Delta deal was found by Cheapflights users on 3/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 4/256:00 am
MYR
-
LEX
1 stop3h 35m
Delta
Sat 5/26:00 am
LEX
-
MYR
1 stop3h 40m
Delta
Deal found 3/23$327
This Kiwi.com deal was found by Cheapflights users on 3/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 6/133:44 pm
CHS
-
LEX
1 stop16h 43m
Multiple Airlines
Sat 6/204:59 pm
LEX
-
CHS
1 stop15h 39m
Multiple Airlines
Deal found 3/19$328

Find flight deals from South Carolina to Lexington

Keep the following information in mind while searching for South Carolina to Lexington flight deals. Data was last updated March 24, 2026.

Most accurate provider

FlightHub
3 stars

Most trusted provider

FlightHub
3 stars

Round-trip from

$269
(American Airlines)

One-way from

$96
(Kiwi.com)

Popular in

October

Cheapest in

June

Average price

$318
Provider with most accurate pricing for Myrtle Beach Intl-Lexington Blue Grass flight deals.
Search Deals
Provider most trusted by Cheapflights users for Myrtle Beach Intl-Lexington Blue Grass flights.
Search Deals
From South Carolina to Lexington Blue Grass
Search Deals
One-way flight from South Carolina to Lexington Blue Grass
Search Deals
Highest demand for flights based on searches. 12% potential increase in price ($46 potential increase over avg. RT price).
Search Deals
Cheapest flight prices on average. 5% potential price decrease ($18 potential savings vs. average RT price).
Search Deals
Average for round-trip flights in March 2026
Search Deals

Cheapflights Fare Finder

 
Customize your flight search to find flights from South Carolina to Lexington that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated March 24, 2026.
Use the filters below to find and compare flights from South Carolina to Lexington that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

Cheapest round-trip

Myrtle BeachLexington

MYR - LEX

MYRLEX

Myrtle Beach Intl

Fri 9/4

6:00 am-9:24 am

1 stop3h 24m

Lexington Blue Grass

Mon 9/7

5:55 pm-11:39 pm

1 stop5h 44m

$335

CharlestonLexington

CHS - LEX

CHSLEX

Charleston

Fri 4/17

5:00 pm-11:59 pm

1 stop6h 59m

Lexington Blue Grass

Sun 4/19

7:00 am-12:25 pm

1 stop5h 25m

$360

Myrtle BeachLexington

MYR - LEX

MYRLEX

Myrtle Beach Intl

Sat 8/29

11:25 am-4:54 pm

1 stop5h 29m

Lexington Blue Grass

Tue 9/1

5:20 am-10:39 am

1 stop5h 19m

$369

Myrtle BeachLexington

MYR - LEX

MYRLEX

Myrtle Beach Intl

Fri 5/22

6:43 pm-8:47 am

2 stops38h 04m

Lexington Blue Grass

Thu 5/28

3:05 pm-8:58 pm

1 stop5h 53m

$370

ColumbiaLexington

CAE - LEX

CAELEX

Columbia Metropolitan

Tue 8/25

2:29 pm-8:27 pm

1 stop5h 58m

Lexington Blue Grass

Sat 8/29

5:20 am-10:10 am

1 stop4h 50m

$374

Myrtle BeachLexington

MYR - LEX

MYRLEX

Myrtle Beach Intl

Thu 4/16

3:15 pm-10:29 pm

1 stop7h 14m

Lexington Blue Grass

Sun 4/19

7:00 am-2:17 pm

1 stop7h 17m

$385

GreenvilleLexington

GSP - LEX

GSPLEX

Greenville

Wed 4/15

5:42 am-9:35 am

1 stop3h 53m

Lexington Blue Grass

Sat 4/18

12:44 pm-4:41 pm

1 stop3h 57m

$387
Quickest round-trip

Myrtle BeachLexington

MYR - LEX

MYRLEX

Myrtle Beach Intl

Fri 5/22

6:00 am-9:21 am

1 stop3h 21m

Lexington Blue Grass

Thu 5/28

8:20 pm-11:58 pm

1 stop3h 38m

$393

SavannahLexington

SAV - LEX

SAVLEX

Savannah/Hilton Head

Tue 4/7

7:11 am-10:58 am

1 stop3h 47m

Lexington Blue Grass

Sat 4/11

7:00 am-2:30 pm

1 stop7h 30m

$423

SavannahLexington

SAV - LEX

SAVLEX

Savannah/Hilton Head

Fri 4/3

7:59 pm-11:53 pm

1 stop3h 54m

Lexington Blue Grass

Tue 4/7

6:00 am-9:16 am

1 stop3h 16m

$435

Flights are sorted by cheapest round-trip flights first.

Deals found on 3/23

Showing 1-10 of 60 resultsSorted by cheapest first
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Best time to book a flight from South Carolina to Lexington

Have a flexible travel schedule? Discover the best time to fly to Lexington from South Carolina with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from South Carolina to Lexington

What is the cheapest month to book a flight from South Carolina to Lexington?

Currently, May is the cheapest month in which you can book a flight from South Carolina to Lexington (average of $31). Flying from South Carolina to Lexington in January is currently the most expensive (average of $105). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

Related info for your journey

Find useful and relevant information for your journey from South Carolina to Lexington. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • What airport do you fly into for flights to Lexington from South Carolina?

    Lexington Blue Grass (LEX), located 5.6 mi from the city center, is the airport you fly into when you book flights from South Carolina to Lexington.

  • How long is the flight from South Carolina to Lexington?

    For as low as $335, Delta can have you in Lexington from South Carolina in 3h 24m. South Carolina and Lexington are separated by a distance of 437 mi. Both multi-stop and nonstop flights can be found to your destination and back.

  • What are the most popular routes from South Carolina to Lexington?

    While some choose either Columbia Metropolitan - Lexington Blue Grass or Myrtle Beach Intl - Lexington Blue Grass, Charlotte Douglas - Lexington Blue Grass is the most popular route from South Carolina to Lexington.

  • Can I find deals for flights from South Carolina to Lexington that include hotel bookings?

    Yes. In addition to deals on South Carolina to Lexington flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from South Carolina to Lexington?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from South Carolina to Lexington.

  • Can I find deals for business class flights from South Carolina to Lexington?

    Yes. Cheapflights offers flight deals from South Carolina to Lexington by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from South Carolina to Lexington?

    Currently, May is the cheapest month in which you can book a flight from South Carolina to Lexington (average of $31). Flying from South Carolina to Lexington in January is currently the most expensive (average of $105). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

Traveling to a place near Lexington?

Book flights to Lexington if you plan to visit one of these locations
Somerset
Danville
Berea
Georgetown
Frankfort

Browse thousands of different options on Cheapflights for your next trip

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Alternative routes for South Carolina to Lexington

See prices for flight routes from nearby airports that may be better suited for you.
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Top 2 airlines flying from South Carolina to Lexington

Discover the top 2 airlines that operate flights from South Carolina to Lexington. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated March 24, 2026.
AirlineCheapestAverageFlexibilityOn-time
American AirlinesCheapest$228Average$389FlexibilityNo cancel feeOn-time71%
DeltaCheapest$228Average$364FlexibilityNo cancel feeOn-timeN/A

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