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Regardless of the time of day you decide to fly, the ticket price will remain around the same. Book flights from Detroit to Latrobe, Pennsylvania as you normally would.
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Useful info, stats and facts about Detroit to Latrobe flights.
This is defined as Detroit Metropolitan Wayne County Airport (DTW) and Latrobe Westmoreland County Airport (LBE). Codes like Latrobe Westmoreland County Airport are often used to just call airports uniquely.