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Lafayette

$249+ Cheap flights from Knoxville to Lafayette (TYS - LFT)

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 3/19. Fares are subject to change and may not be available on all flights or dates of travel.
TYS — LFT
Mar 29 — Apr 51
Sun 3/29
Sun 4/5
1 adult, Economy
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Cheap flight deals from Knoxville to Lafayette

Cheapest flights from Knoxville to Lafayette
Explore the most affordable flight options available from Knoxville to Lafayette. Find the lowest fares from popular airlines and budget airlines, with prices last updated on February 27, 2026.

This American Airlines deal was found by Cheapflights users on 2/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 3/195:33 am
TYS
-
LFT
1 stop5h 25m
American Airlines
Mon 3/236:20 pm
LFT
-
TYS
1 stop4h 31m
American Airlines
Deal found 2/23$269
This American Airlines deal was found by Cheapflights users on 2/24. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 4/161:20 pm
TYS
-
LFT
1 stop5h 22m
American Airlines
Sun 4/196:12 pm
LFT
-
TYS
1 stop4h 44m
American Airlines
Deal found 2/24$303
This Delta deal was found by Cheapflights users on 2/24. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 3/195:10 pm
TYS
-
LFT
1 stop5h 59m
Delta
Wed 6/105:15 pm
LFT
-
TYS
1 stop5h 31m
Delta
Deal found 2/24$334
This American Airlines deal was found by Cheapflights users on 2/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 2/276:21 pm
TYS
-
LFT
1 stop5h 37m
American Airlines
Tue 3/32:34 pm
LFT
-
TYS
1 stop7h 46m
American Airlines
Deal found 2/23$354
This United Airlines deal was found by Cheapflights users on 2/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 2/254:55 pm
TYS
-
LFT
1 stop5h 36m
United Airlines
Sun 3/15:15 am
LFT
-
TYS
1 stop7h 31m
United Airlines
Deal found 2/25$369
This American Airlines deal was found by Cheapflights users on 2/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 3/195:33 am
TYS
-
LFT
1 stop5h 25m
American Airlines
Sun 3/226:20 pm
LFT
-
TYS
1 stop4h 31m
American Airlines
Deal found 2/23$402
This United Airlines deal was found by Cheapflights users on 2/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 4/1811:40 am
TYS
-
LFT
1 stop7h 06m
United Airlines
Tue 4/216:30 am
LFT
-
TYS
1 stop10h 45m
United Airlines
Deal found 2/22$438
This Delta deal was found by Cheapflights users on 2/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 4/165:54 pm
TYS
-
LFT
1 stop5h 18m
Delta
Sun 4/196:05 am
LFT
-
TYS
1 stop4h 12m
Delta
Deal found 2/25$444
This American Airlines deal was found by Cheapflights users on 2/24. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 2/264:29 pm
TYS
-
LFT
1 stop7h 29m
American Airlines
Sun 3/15:35 am
LFT
-
TYS
1 stop4h 56m
American Airlines
Deal found 2/24$452

Find flight deals from Knoxville to Lafayette

Discover tips and strategies to find the most affordable flight options for your journey from Knoxville (TYS) to Lafayette (LFT). Learn about various techniques such as flexible date searches, comparing prices across and setting up price alerts. Use these methods to find the cheapest flights available for your travel needs. Data last updated February 27, 2026.

Most accurate provider

FlightHub
3 stars

Most trusted provider

FlightHub
3 stars

Round-trip from

$269
(American Airlines)

One-way from

$249
(Delta)
Provider with most accurate pricing for Knoxville McGhee Tyson-Lafayette Regional flight deals.
Search Deals
Provider most trusted by Cheapflights users for Knoxville McGhee Tyson-Lafayette Regional flights.
Search Deals
From Knoxville McGhee Tyson to Lafayette Regional
Search Deals
One-way flight from Knoxville McGhee Tyson to Lafayette Regional
Search Deals

Cheapflights Fare Finder

 
Customize your flight search to find flights from Knoxville to Lafayette that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated February 27, 2026.
Use the filters below to find and compare flights from Knoxville to Lafayette that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

KnoxvilleLafayette

TYS - LFT

TYSLFT

Knoxville McGhee Tyson

Thu 4/16

5:54 pm-10:12 pm

1 stop5h 18m

Lafayette Regional

Sun 4/19

6:05 am-11:17 am

1 stop4h 12m

$369

KnoxvilleLafayette

TYS - LFT

TYSLFT

Knoxville McGhee Tyson

Thu 3/19

5:33 am-9:58 am

1 stop5h 25m

Lafayette Regional

Sun 3/22

6:20 pm-11:51 pm

1 stop4h 31m

$402

KnoxvilleLafayette

TYS - LFT

TYSLFT

Knoxville McGhee Tyson

Tue 3/24

7:05 am-11:25 am

1 stop5h 20m

Lafayette Regional

Sun 3/29

7:29 pm-7:56 pm

1 stop23h 27m

$473

KnoxvilleLafayette

TYS - LFT

TYSLFT

Knoxville McGhee Tyson

Sat 4/18

7:05 am-11:16 am

1 stop5h 11m

Lafayette Regional

Tue 4/21

6:30 am-11:41 pm

1 stop16h 11m

$478

KnoxvilleLafayette

TYS - LFT

TYSLFT

Knoxville McGhee Tyson

Tue 3/10

4:55 pm-9:22 pm

1 stop5h 27m

Lafayette Regional

Sat 3/14

5:15 am-6:10 pm

1 stop11h 55m

$583

KnoxvilleLafayette

TYS - LFT

TYSLFT

Knoxville McGhee Tyson

Tue 3/24

5:10 pm-10:09 pm

1 stop5h 59m

$249

KnoxvilleLafayette

TYS - LFT

TYSLFT

Knoxville McGhee Tyson

Thu 3/19

12:03 pm-4:27 pm

1 stop5h 24m

$249

KnoxvilleLafayette

TYS - LFT

TYSLFT

Knoxville McGhee Tyson

Tue 3/24

7:00 am-5:39 pm

2 stops11h 39m

$448

KnoxvilleLafayette

TYS - LFT

TYSLFT

Knoxville McGhee Tyson

Thu 3/19

7:02 am-5:50 pm

2 stops11h 48m

$485

Flights are sorted by cheapest round-trip flights first.

Deals found on 2/24

Sorted by cheapest first

Compare providers for flights from Knoxville to Lafayette

Provider information is updated monthly. Please note that these providers often have deals for this flight, but the availability may vary on a day-by-day basis on Cheapflights.
Use the table below to compare price accuracy, trust ratings, and cancellation policies for each provider offering flight deals from Knoxville to Lafayette in February.
ProviderPrice AccuracyTrust Score*
FlightHubPrice Accuracy3 starsTrust Score*3 stars
ExpediaPrice Accuracy1 starTrust Score*3 stars

*The Trust Score is based on feedback from users after their booking experience. It measures overall satisfaction, helping us identify issues like hidden fees, problems during the ticketing process, and the quality of customer service. This score is our best indicator of the provider's quality and reliability.

  • Most accurate provider: When it comes to deals on Knoxville-Lafayette flights, users find the pricing of FlightHub to be most consistent on Cheapflights vs. FlightHub Users can find the same prices on Knoxville-Lafayette flight deals on Cheapflights vs. FlightHub >95% of the time. Price accuracy is based on data collected from Knoxville-Lafayette flight searches over the past month and is updated monthly.
  • Most trusted provider: When it comes to deals on Knoxville-Lafayette flights, Cheapflights users trust FlightHub the most. FlightHub has received a user feedback score of 3 out of 3 stars (3 being the best), meaning they have been trusted the most by Cheapflights users looking for Knoxville-Lafayette flight deals. Provider user feedback score is based on Cheapflights searches over the past month and is updated monthly.

Best time to book a flight from Knoxville to Lafayette

Have a flexible travel schedule? Discover the best time to fly to Lafayette from Knoxville with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Knoxville to Lafayette

What is the cheapest month to book a flight from Knoxville to Lafayette?

Currently, October is the cheapest month in which you can book a flight from Knoxville to Lafayette (average of $166). Flying from Knoxville to Lafayette in December is currently the most expensive (average of $376). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

Reviews of airlines servicing Lafayette

Get insights into the airlines that provide service to Lafayette. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Lafayette. Reviews last updated February 27, 2026.
See what other customers who have flown with American Airlines from Knoxville to Lafayette have to say. You can also see how each airline compares in terms of entertainment options, comfort, food, crew/service, and boarding process.
American Airlines
7.2
Good
11,357 reviews

Overall

7.2

Comfort

7.2

Food

6.4

Boarding

7.5

Crew

8.0

Entertainment

6.9

Reviews

1 / 20
2.0
Mediocre

Susie,Jan 2026

CLT - TPA

This flight was delayed 3 or 4 times. We had boarded the plane, sat on plane for a good 30 minutes, then we had to board the aircraft, walk to a different gate, wait and then board another aircraft. We arrived in Tampa 4 hours later than the original booking. I feel there should have been some sort of compensation especially for the advantage members.
American Airlines
7.2
Good
11,357 reviews
American Airlines
7.2
Good
11,357 reviews

Overall

7.2

Comfort

7.2

Food

6.4

Boarding

7.5

Crew

8.0

Entertainment

6.9

Reviews

1 / 20
2.0
Mediocre

Susie,Jan 2026

CLT - TPA

This flight was delayed 3 or 4 times. We had boarded the plane, sat on plane for a good 30 minutes, then we had to board the aircraft, walk to a different gate, wait and then board another aircraft. We arrived in Tampa 4 hours later than the original booking. I feel there should have been some sort of compensation especially for the advantage members.

Related info for your journey

Find useful and relevant information for your journey from Knoxville to Lafayette. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • How long is the flight from Knoxville to Lafayette?

    For as low as $369, Delta can have you in Lafayette from Knoxville in 5h 18m. Airlines will cover a distance of 603 mi. When browsing for deals, the options you’ll see will be for both nonstop flights and flights with stops.

  • What is the cheapest airline to fly from Knoxville to Lafayette round-trip?

    Cheapflights users have booked flights from Knoxville to Lafayette round-trip from $323.

  • Can I find deals for flights from Knoxville to Lafayette that include hotel bookings?

    Yes. In addition to deals on Knoxville to Lafayette flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Knoxville to Lafayette?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Knoxville to Lafayette.

  • Can I find deals for business class flights from Knoxville to Lafayette?

    Yes. Cheapflights offers flight deals from Knoxville to Lafayette by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Knoxville to Lafayette?

    Currently, October is the cheapest month in which you can book a flight from Knoxville to Lafayette (average of $166). Flying from Knoxville to Lafayette in December is currently the most expensive (average of $376). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

Traveling to a place near Lafayette?

Book flights to Lafayette if you plan to visit one of these locations
Opelousas

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Top airline flying from Knoxville to Lafayette

Discover the top airline that operate flights from Knoxville to Lafayette. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated February 27, 2026.
AirlineCheapestAverageFlexibilityOn-time
American AirlinesCheapest$323Average$488FlexibilityNo cancel feeOn-time71%

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