HomeSearch by dateVacation packagesHotelsFlight dealsCar rentalTravel tips & news
Lafayette

$289+ Cheap flights from Knoxville to Lafayette (TYS - LFT)

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 9/13. Fares are subject to change and may not be available on all flights or dates of travel.
TYS — LFT
May 30 — Jun 61
Sat 5/30
Sat 6/6
1 adult, Economy
We work with more than 300 partners to bring you better travel deals

Find cheap flights from Knoxville to Lafayette with Cheapflights

1. Tell us where you want to go

Enter your travel information like dates, passengers, trip type (one-way or round trip), and preferred cabin class then click “Find deals”

2. Select your favorite providers

We find the providers serving your travel needs. Choose up to four travel providers to compare side-by-side for flights, hotels, or car rentals.

3. Compare prices and book

Review each provider’s pricing and select the best option for you! Book through your favorite provider’s website for a seamless experience.

Cheap flight deals from Knoxville to Lafayette

Cheapest flights from Knoxville to Lafayette
Explore the most affordable flight options available from Knoxville to Lafayette. Find the lowest fares from popular airlines and budget airlines, with prices last updated on April 30, 2026.

This American Airlines deal was found by Cheapflights users on 4/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 5/146:00 am
TYS
-
LFT
1 stop5h 12m
American Airlines
Mon 5/186:12 pm
LFT
-
TYS
1 stop4h 44m
American Airlines
Deal found 4/29$339
This American Airlines deal was found by Cheapflights users on 4/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 9/16:00 am
TYS
-
LFT
1 stop5h 19m
American Airlines
Tue 9/88:10 am
LFT
-
TYS
1 stop6h 47m
American Airlines
Deal found 4/28$346
This American Airlines deal was found by Cheapflights users on 4/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 5/21:20 pm
TYS
-
LFT
1 stop5h 22m
American Airlines
Sat 5/95:42 am
LFT
-
TYS
1 stop5h 48m
American Airlines
Deal found 4/27$347
This American Airlines deal was found by Cheapflights users on 4/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 5/33:58 pm
TYS
-
LFT
1 stop7h 11m
American Airlines
Sun 5/105:07 pm
LFT
-
TYS
1 stop5h 49m
American Airlines
Deal found 4/28$602
This United Airlines deal was found by Cheapflights users on 4/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 9/16:30 am
TYS
-
LFT
3 stops17h 25m
United Airlines
Tue 9/85:25 am
LFT
-
TYS
2 stops17h 32m
United Airlines
Deal found 4/28$675

Find flight deals from Knoxville to Lafayette

Discover tips and strategies to find the most affordable flight options for your journey from Knoxville (TYS) to Lafayette (LFT). Learn about various techniques such as flexible date searches, comparing prices across and setting up price alerts. Use these methods to find the cheapest flights available for your travel needs. Data last updated April 30, 2026.

Most accurate provider

FlightHub
3 stars

Most trusted provider

FlightHub
3 stars

Round-trip from

$339
(American Airlines)

One-way from

$289
(American Airlines)
Provider with most accurate pricing for Knoxville McGhee Tyson-Lafayette Regional flight deals.
Search Deals
Provider most trusted by Cheapflights users for Knoxville McGhee Tyson-Lafayette Regional flights.
Search Deals
From Knoxville McGhee Tyson to Lafayette Regional
Search Deals
One-way flight from Knoxville McGhee Tyson to Lafayette Regional
Search Deals

Cheapflights Fare Finder

 
Customize your flight search to find flights from Knoxville to Lafayette that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated April 30, 2026.
Use the filters below to find and compare flights from Knoxville to Lafayette that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

Cheapest round-trip
Quickest round-trip

KnoxvilleLafayette

TYS - LFT

TYSLFT

Knoxville McGhee Tyson

Thu 5/14

6:00 am-10:12 am

1 stop5h 12m

Lafayette Regional

Mon 5/18

6:12 pm-11:56 pm

1 stop4h 44m

$339

KnoxvilleLafayette

TYS - LFT

TYSLFT

Knoxville McGhee Tyson

Tue 9/1

6:00 am-10:19 am

1 stop5h 19m

Lafayette Regional

Tue 9/8

10:49 am-9:57 pm

2 stops10h 08m

$379

KnoxvilleLafayette

TYS - LFT

TYSLFT

Knoxville McGhee Tyson

Tue 9/1

6:30 am-10:55 pm

3 stops17h 25m

Lafayette Regional

Tue 9/8

5:25 am-11:57 pm

2 stops17h 32m

$675
Cheapest one-way
Quickest one-way

KnoxvilleLafayette

TYS - LFT

TYSLFT

Knoxville McGhee Tyson

Sun 9/13

6:00 am-10:32 am

1 stop5h 32m

$289

KnoxvilleLafayette

TYS - LFT

TYSLFT

Knoxville McGhee Tyson

Sun 9/13

5:45 am-6:21 pm

2 stops13h 36m

$498

Flights are sorted by cheapest round-trip flights first.

Deals found on 4/29

Sorted by cheapest first

Compare providers for flights from Knoxville to Lafayette

Provider information is updated monthly. Please note that these providers often have deals for this flight, but the availability may vary on a day-by-day basis on Cheapflights.
Use the table below to compare price accuracy, trust ratings, and cancellation policies for each provider offering flight deals from Knoxville to Lafayette in April.
ProviderPrice AccuracyTrust Score*
ExpediaPrice Accuracy1 starTrust Score*3 stars
FlightHubPrice Accuracy3 starsTrust Score*3 stars

*The Trust Score is based on feedback from users after their booking experience. It measures overall satisfaction, helping us identify issues like hidden fees, problems during the ticketing process, and the quality of customer service. This score is our best indicator of the provider's quality and reliability.

  • Most accurate provider: When it comes to deals on Knoxville-Lafayette flights, users find the pricing of FlightHub to be most consistent on Cheapflights vs. FlightHub Users can find the same prices on Knoxville-Lafayette flight deals on Cheapflights vs. FlightHub >95% of the time. Price accuracy is based on data collected from Knoxville-Lafayette flight searches over the past month and is updated monthly.
  • Most trusted provider: When it comes to deals on Knoxville-Lafayette flights, Cheapflights users trust FlightHub the most. FlightHub has received a user feedback score of 3 out of 3 stars (3 being the best), meaning they have been trusted the most by Cheapflights users looking for Knoxville-Lafayette flight deals. Provider user feedback score is based on Cheapflights searches over the past month and is updated monthly.

Best time to book a flight from Knoxville to Lafayette

Have a flexible travel schedule? Discover the best time to fly to Lafayette from Knoxville with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Related info for your journey

Find useful and relevant information for your journey from Knoxville to Lafayette. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • How long is the flight from Knoxville to Lafayette?

    For as low as $339, American Airlines can have you in Lafayette from Knoxville in 5h 12m. Airlines will cover a distance of 603 mi.

  • Can I find deals for flights from Knoxville to Lafayette that include hotel bookings?

    Yes. In addition to deals on Knoxville to Lafayette flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Knoxville to Lafayette?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Knoxville to Lafayette.

  • Can I find deals for business class flights from Knoxville to Lafayette?

    Yes. Cheapflights offers flight deals from Knoxville to Lafayette by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

See more FAQs

Traveling to a place near Lafayette?

Book flights to Lafayette if you plan to visit one of these locations
Opelousas

Browse thousands of different options on Cheapflights for your next trip

Toggle through the tabs below to find thousands of options on Cheapflights for your next trip.

100% Free

Cheapflights is completely free to use, so you can start saving the moment you arrive.

Book with Flexibility

Our users can plan ahead with confidence and find flights with no change fees

Travel Smart

Millions of people come to us for their flight needs every year. We help make travel planning easy by providing useful insights and data-driven graphs that can inform your decisions.