In terms of precipitation, rainfall in La Serena ranges from 0.0 - 1.2 inches per month. June is typically the wettest month, when rainfall can reach 1.2 in. January is typically the driest time to visit La Serena when rainfall is around 0.0 in.

If weather is an important factor for your trip to La Serena, use this chart to help with planning. For those seeking warmer temperatures, January is the ideal time of year to visit, when temperatures reach an average of 62.6 F. Travelers looking to avoid the cold should look outside of June, when temperatures are typically at their lowest (around 51.8 F).

What is the cheapest time of day to fly from DEN to LSC?

Regardless of the time of day you decide to fly, the ticket price will remain around the same. Book flights from Denver to La Serena as you normally would.

Can I find deals for flights from Denver to La Serena that include hotel bookings?

Yes. In addition to deals on Denver to La Serena flights, Cheapflights offers vacation packages that include both flights and hotel.

How can I find direct flights from Denver to La Serena?

After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Denver to La Serena.

Can I find deals for business class flights from Denver to La Serena?

Yes. Cheapflights offers flight deals from Denver to La Serena by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

$1,011+ Flights from Denver to La Serena

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Cheap flight deals from Denver to La Serena

Round-trip from	$1,011 (LATAM Airlines)

From Denver Intl to La Serena La Florida

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Find flight deals from Denver to La Serena

Cheapest flights from Denver to La Serena
Explore the most affordable flight options available from Denver to La Serena. Find the lowest fares from popular airlines and budget airlines, with prices last updated on julio 30, 2025.

vie. 8/2212:10 pmDEN - LSC

2 stops28h 45mLATAM Airlines

mar. 8/269:45 amLSC - DEN

2 stops36h 31mLATAM Airlines

Deal found 7/28

$1,011

Best flights from Denver to La Serena
Discover carefully curated flight deals from Denver to La Serena that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated julio 30, 2025.

vie. 8/2212:10 pmDEN - LSC

2 stops28h 45mLATAM Airlines

mar. 8/269:45 amLSC - DEN

2 stops36h 31mLATAM Airlines

Deal found 7/28

$1,011

Last-minute flights from Denver to La Serena
Discover last-minute flight deals from Denver to La Serena. Data last updated julio 30, 2025 and is based on user searches.

vie. 8/2212:10 pmDEN - LSC

2 stops28h 45mLATAM Airlines

mar. 8/269:45 amLSC - DEN

2 stops36h 31mLATAM Airlines

Deal found 7/28

$1,011

Fly from

Fly to

Route

Depart

Return

Price

DenverLa Serena

DEN - LSC

DENLSC

Denver Intl

vie. 8/22

12:10 pm-6:55 pm

2 stops28h 45m

La Serena La Florida

mar. 8/26

9:45 am-8:16 pm

2 stops36h 31m

$1,011

Flights are sorted by cheapest round-trip flights first.

Deals found on 7/28

Best time to book a flight from Denver to La Serena

Have a flexible travel schedule? Discover the best time to fly to La Serena from Denver with our price prediction graph.

Estimated round-trip price

Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Reviews of airlines servicing La Serena

Read reviews from past customers who have flown LATAM Airlines from Denver to La Serena. Users can see the overall rating for each airline as well as how each is rated in terms of entertainment options, comfort, food, crew/service, and boarding process.

LATAM Airlines

7.5

Good

1,822 reviews

Reviews

1 / 20

4.0

Okay

Murilo,Jun 2025

SFO - LAX

I had mixed feelings regarding this flight. Called several times Latam and Delta regarding the purchase of checked baggage and price. I was told 80 dollars, could not buy it ahead of time,, they told me it was not Possible, that I had to buy at the airport. Check in my luggage the attendant says 80 dollars but I was charged 200 . No one could get me a solid answer why. Very disappointing

LATAM Airlines

7.5

Good

1,822 reviews

LATAM Airlines

7.5

Good

1,822 reviews

Reviews

1 / 20

4.0

Okay

Murilo,Jun 2025

SFO - LAX

Related info for your journey

Can I find deals for flights from Denver to La Serena that include hotel bookings?
Yes. In addition to deals on Denver to La Serena flights, Cheapflights offers vacation packages that include both flights and hotel.
How can I find direct flights from Denver to La Serena?
After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Denver to La Serena.
Can I find deals for business class flights from Denver to La Serena?
Yes. Cheapflights offers flight deals from Denver to La Serena by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

Browse thousands of different options on Cheapflights for your next trip

Alternative routes for Denver to La Serena

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$1,011+ Cheap flights from Denver (DEN) to La Serena (LSC)

This is the cheapest round-trip flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 8/22. Fares are subject to change and may not be available on all flights or dates of travel.

Find cheap flights from Denver to La Serena with Cheapflights

1. Tell us where you want to go

2. Select your favorite providers

3. Compare prices and book

Cheap flight deals from Denver to La Serena

Round-trip from

Find flight deals from Denver to La Serena

Cheapest flights from Denver to La SerenaExplore the most affordable flight options available from Denver to La Serena. Find the lowest fares from popular airlines and budget airlines, with prices last updated on julio 30, 2025.

Explore the most affordable flight options available from Denver to La Serena. Find the lowest fares from popular airlines and budget airlines, with prices last updated on julio 30, 2025.

Cheapflights Fare Finder

Use the filters below to find and compare flights from Denver to La Serena that are best for you.

Best time to book a flight from Denver to La Serena

Have a flexible travel schedule? Discover the best time to fly to La Serena from Denver with our price prediction graph.

Reviews of airlines servicing La Serena

Read reviews from past customers who have flown LATAM Airlines from Denver to La Serena. Users can see the overall rating for each airline as well as how each is rated in terms of entertainment options, comfort, food, crew/service, and boarding process.

Related info for your journey

Find useful and relevant information for your journey from Denver to La Serena. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

Can I find deals for flights from Denver to La Serena that include hotel bookings?

How can I find direct flights from Denver to La Serena?

Can I find deals for business class flights from Denver to La Serena?

Browse thousands of different options on Cheapflights for your next trip

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Alternative routes for Denver to La Serena

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Cheapest flights from Denver to La Serena
Explore the most affordable flight options available from Denver to La Serena. Find the lowest fares from popular airlines and budget airlines, with prices last updated on julio 30, 2025.