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$50+ Cheap flights from Tampa to Knoxville (PIE - TYS)

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 9/19. Fares are subject to change and may not be available on all flights or dates of travel.
PIE — TYS
Aug 19 — Aug 261
Tue 8/19
Tue 8/26
1 adult, Economy
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Cheapflights Tip: The best prices from Tampa St. Petersburg to Knoxville McGhee Tyson are usually found in March or February, booked 52 days in advance, depart on a Tuesday or Wednesday and return on a Tuesday

Cheap flight deals from St Petersburg to Knoxville

Discover tips and strategies to find the most affordable flight options for your journey from St Petersburg (PIE) to Knoxville (TYS). Learn about various techniques such as flexible date searches, comparing prices across and setting up price alerts. Use these methods to find the cheapest flights available for your travel needs. Data last updated August 14, 2025.

Round-trip from

$80
(Cheapflightsfares)

One-way from

$50
(Cheapflightsfares)

Popular in

November

Cheapest in

March

Average price

$135
From Tampa St. Petersburg to Knoxville McGhee Tyson
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One-way flight from Tampa St. Petersburg to Knoxville McGhee Tyson
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Highest demand for flights based on searches. 27% potential increase in price ($55 potential increase over avg. RT price).
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Cheapest flight prices on average. 6% potential price decrease ($9 potential savings vs. average RT price).
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Average for round-trip flights in August 2025
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Find flight deals from St Petersburg to Knoxville

Cheapest flights from St Petersburg to Knoxville
Explore the most affordable flight options available from St Petersburg to Knoxville. Find the lowest fares from popular airlines and budget airlines, with prices last updated on August 14, 2025.

This Cheapflightsfares deal was found by Cheapflights users on 8/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Cheapflightsfares is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 9/86:05 pmPIE - TYS
Nonstop1h 37mAllegiant Air
Fri 9/129:57 pmTYS - PIE
Nonstop1h 41mAllegiant Air
Deal found 8/13$80
This Kiwi.com deal was found by Cheapflights users on 8/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 9/127:30 pmPIE - TYS
Nonstop1h 37mAllegiant Air
Fri 9/197:34 pmTYS - PIE
Nonstop1h 41mAllegiant Air
Deal found 8/13$107
This Kiwi.com deal was found by Cheapflights users on 8/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 9/277:45 amPIE - TYS
Nonstop1h 38mAllegiant Air
Sun 9/284:22 pmTYS - PIE
Nonstop1h 41mAllegiant Air
Deal found 8/13$111
This Cheapflightsfares deal was found by Cheapflights users on 8/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Cheapflightsfares is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 9/195:07 pmPIE - TYS
Nonstop1h 37mAllegiant Air
Fri 9/263:25 pmTYS - PIE
Nonstop1h 41mAllegiant Air
Deal found 8/11$117
This Cheapflightsfares deal was found by Cheapflights users on 8/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Cheapflightsfares is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 8/3012:30 pmPIE - TYS
Nonstop1h 41mAllegiant Air
Tue 9/211:51 amTYS - PIE
Nonstop1h 40mAllegiant Air
Deal found 8/14$140
This Kiwi.com deal was found by Cheapflights users on 8/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 10/66:59 pmPIE - TYS
Nonstop1h 37mAllegiant Air
Thu 10/99:25 pmTYS - PIE
Nonstop1h 39mAllegiant Air
Deal found 8/13$142
This Cheapflightsfares deal was found by Cheapflights users on 8/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Cheapflightsfares is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 9/113:51 pmPIE - TYS
Nonstop1h 38mAllegiant Air
Mon 9/158:32 pmTYS - PIE
Nonstop1h 41mAllegiant Air
Deal found 8/14$147
This Cheapflightsfares deal was found by Cheapflights users on 8/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Cheapflightsfares is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 10/13:14 pmPIE - TYS
Nonstop1h 37mAllegiant Air
Sun 10/59:25 pmTYS - PIE
Nonstop1h 39mAllegiant Air
Deal found 8/12$149
This Cheapflightsfares deal was found by Cheapflights users on 8/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Cheapflightsfares is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 9/57:30 pmPIE - TYS
Nonstop1h 37mAllegiant Air
Sun 9/71:20 pmTYS - PIE
Nonstop1h 41mAllegiant Air
Deal found 8/12$153
This Cheapflightsfares deal was found by Cheapflights users on 8/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Cheapflightsfares is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 8/178:55 pmPIE - TYS
Nonstop1h 41mAllegiant Air
Tue 8/194:33 pmTYS - PIE
Nonstop1h 40mAllegiant Air
Deal found 8/13$156
This Kiwi.com deal was found by Cheapflights users on 8/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/243:48 pmPIE - TYS
Nonstop1h 37mAllegiant Air
Sun 10/265:34 pmTYS - PIE
1 stop5h 55mAllegiant Air
Deal found 8/12$163

Cheapflights Fare Finder

 
Customize your flight search to find flights from St Petersburg to Knoxville that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated August 14, 2025.
Use the filters below to find and compare flights from Tampa to Knoxville that are best for you.

Fly from

St Petersburg

Fly to

Knoxville

Route

Depart

Return

Price

TampaKnoxville

PIE - TYS

PIETYS

Tampa St. Petersburg

Sat 9/13

6:27 pm-8:05 pm

Nonstop1h 38m

Knoxville McGhee Tyson

Sat 9/20

10:57 am-12:38 pm

Nonstop1h 41m

$80

TampaKnoxville

PIE - TYS

PIETYS

Tampa St. Petersburg

Mon 9/8

6:05 pm-7:42 pm

Nonstop1h 37m

Knoxville McGhee Tyson

Fri 9/12

9:57 pm-11:38 pm

Nonstop1h 41m

$80

TampaKnoxville

PIE - TYS

PIETYS

Tampa St. Petersburg

Fri 9/12

7:30 pm-9:07 pm

Nonstop1h 37m

Knoxville McGhee Tyson

Fri 9/19

7:34 pm-9:15 pm

Nonstop1h 41m

$107

TampaKnoxville

PIE - TYS

PIETYS

Tampa St. Petersburg

Fri 9/19

5:07 pm-6:44 pm

Nonstop1h 37m

Knoxville McGhee Tyson

Mon 9/22

9:49 pm-11:30 pm

Nonstop1h 41m

$107

TampaKnoxville

PIE - TYS

PIETYS

Tampa St. Petersburg

Sat 9/27

7:45 am-9:23 am

Nonstop1h 38m

Knoxville McGhee Tyson

Sun 9/28

4:22 pm-6:03 pm

Nonstop1h 41m

$111

TampaKnoxville

PIE - TYS

PIETYS

Tampa St. Petersburg

Fri 9/19

5:07 pm-6:44 pm

Nonstop1h 37m

Knoxville McGhee Tyson

Fri 9/26

3:25 pm-5:06 pm

Nonstop1h 41m

$117

TampaKnoxville

PIE - TYS

PIETYS

Tampa St. Petersburg

Sat 8/30

12:30 pm-2:11 pm

Nonstop1h 41m

Knoxville McGhee Tyson

Tue 9/2

11:51 am-1:31 pm

Nonstop1h 40m

$140

TampaKnoxville

PIE - TYS

PIETYS

Tampa St. Petersburg

Mon 10/6

6:59 pm-8:36 pm

Nonstop1h 37m

Knoxville McGhee Tyson

Thu 10/9

9:25 pm-11:04 pm

Nonstop1h 39m

$142

TampaKnoxville

PIE - TYS

PIETYS

Tampa St. Petersburg

Thu 9/11

3:51 pm-5:29 pm

Nonstop1h 38m

Knoxville McGhee Tyson

Mon 9/15

8:32 pm-10:13 pm

Nonstop1h 41m

$147

TampaKnoxville

PIE - TYS

PIETYS

Tampa St. Petersburg

Wed 10/1

3:14 pm-4:51 pm

Nonstop1h 37m

Knoxville McGhee Tyson

Sun 10/5

9:25 pm-11:04 pm

Nonstop1h 39m

$149

Flights are sorted by cheapest round-trip flights first.

Deals found on 8/12

Showing 1-10 of 23 results
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Best time to book a flight from St Petersburg to Knoxville

Have a flexible travel schedule? Discover the best time to fly to Knoxville from St Petersburg with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Tampa to Knoxville

How far ahead should I book a flight from Tampa to Knoxville?

Use this chart to determine the optimal time to book a round-trip flight from St Petersburg to Knoxville. Price data was last updated on August 8, 2025.

To ensure you get the cheapest price possible for a flight from Tampa to Knoxville, you should look to book at least 52 days in advance of your intended travel date. The price of your flight may increase if you delay and leave booking until a week or so before departure.

What is the cheapest month to book a flight from Tampa to Knoxville?

Currently, January is the cheapest month in which you can book a flight from Tampa to Knoxville (average of $294). Flying from Tampa to Knoxville in March is currently the most expensive (average of $376). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

What is the cheapest time of day to fly from PIE to TYS?

Find hourly flight availability from St Petersburg to Knoxville. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated August 14, 2025.

One of the essential ways to save on airfare from Tampa to Knoxville is to remain as flexible as possible. Flights that are at noon tend to be the most expensive. A flight in the evening could potentially save you up to 18% on airfare.

What is the cheapest day to fly from Tampa to Knoxville?

Use this chart to determine the cheapest time to fly round-trip from St Petersburg to Knoxville. Price data was last updated on August 10, 2025.

Travelers seeking maximum savings on their Tampa to Knoxville flight should consider departing on Tuesday mornings when fares are most often at their lowest. Sunday afternoons flights should be avoided if possible as fares are typically the most expensive at this time.

Reviews of airlines servicing Knoxville

Get insights into the airlines that provide service to Knoxville. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Knoxville. Reviews last updated August 14, 2025.
Read through reviews of airlines operating flights from Tampa to Knoxville, such as Allegiant Air. Reviews also offer insight into each airline's entertainment options, comfort, food, crew/service, and boarding process.
Allegiant Air
7.2
Good
701 reviews

Boarding

7.6

Entertainment

5.5

Overall

7.2

Comfort

6.8

Food

5.9

Crew

8.1

Reviews

1 / 20
10.0
Excellent

Joellen,Aug 2024

LAS - GEG

Boarding was a hassle. I’ve had the same guy before. Never enjoy seeing him.
Allegiant Air
7.2
Good
701 reviews
Allegiant Air
7.2
Good
701 reviews

Boarding

7.6

Entertainment

5.5

Overall

7.2

Comfort

6.8

Food

5.9

Crew

8.1

Reviews

1 / 20
10.0
Excellent

Joellen,Aug 2024

LAS - GEG

Boarding was a hassle. I’ve had the same guy before. Never enjoy seeing him.

Related info for your journey

Find useful and relevant information for your journey from St Petersburg to Knoxville. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • How popular is this Tampa to Knoxville flight route?

    The Tampa St. Petersburg to Knoxville McGhee Tyson flight path was viewed by 7 users in the past month. Keep an eye out for changes in search interest prior to high and low season.

  • What is the cheapest airline to fly from Tampa to Knoxville round-trip?

    Currently priced at $85, Allegiant Air will fly you from Tampa to Knoxville and back. In addition to Allegiant Air, many other airlines offer competitively priced options for your trip. This flight start at 40% lower than the current average price 3 months from now.

  • What are the cheapest flights from Tampa to Knoxville?

    On average you can expect to pay $117 for a flight from Tampa to Knoxville. The cheapest flight overall is $55 while the most popular route, (Tampa St. Petersburg - Knoxville McGhee Tyson) is currently priced at $80.

  • Can I find deals for flights from St Petersburg to Knoxville that include hotel bookings?

    Yes. In addition to deals on St Petersburg to Knoxville flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from St Petersburg to Knoxville?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from St Petersburg to Knoxville.

  • Can I find deals for business class flights from St Petersburg to Knoxville?

    Yes. Cheapflights offers flight deals from St Petersburg to Knoxville by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Tampa to Knoxville?

    Currently, January is the cheapest month in which you can book a flight from Tampa to Knoxville (average of $294). Flying from Tampa to Knoxville in March is currently the most expensive (average of $376). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

Traveling to a place near Knoxville?

Book flights to Knoxville if you plan to visit one of these locations
Morristown
Cherokee
Corbin
Alcoa
Oak Ridge
Murphy

Browse thousands of different options on Cheapflights for your next trip

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Alternative routes for St Petersburg to Knoxville

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Top airline flying from St Petersburg to Knoxville

Discover the top airline that operate flights from St Petersburg to Knoxville. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated August 14, 2025.
AirlineCheapestAverageFlexibilityOn-time
Allegiant AirCheapest$85Average$141FlexibilityNo cancel feeOn-time88%

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