$163+ Cheap flights from Spokane to Knoxville (GEG - TYS)
This is the cheapest round-trip flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 10/13. Fares are subject to change and may not be available on all flights or dates of travel.
GEG — TYS
Oct 21 — Oct 281
Round-trip
1 adult, Economy
We work with more than 300 partners to bring you better travel deals
Find cheap flights from Spokane to Knoxville with Cheapflights
1. Tell us where you want to go
Enter your travel information like dates, passengers, trip type (one-way or round trip), and preferred cabin class then click “Find deals”2. Select your favorite providers
We find the providers serving your travel needs. Choose up to four travel providers to compare side-by-side for flights, hotels, or car rentals.3. Compare prices and book
Review each provider’s pricing and select the best option for you! Book through your favorite provider’s website for a seamless experience.Cheap flight deals from Spokane to Knoxville
Cheapest
Best
Last-minute
One-way
Cheapest flights from Spokane to KnoxvilleExplore the most affordable flight options available from Spokane to Knoxville. Find the lowest fares from popular airlines and budget airlines, with prices last updated on September 21, 2026.
Explore the most affordable flight options available from Spokane to Knoxville. Find the lowest fares from popular airlines and budget airlines, with prices last updated on September 21, 2026.
This Delta deal was found by Cheapflights users on 9/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 11/271:08 pm -
1 stop6h 04m
Thu 12/35:40 am -
1 stop9h 26m
Deal found 9/16![Delta logo]()
$334
This Delta deal was found by Cheapflights users on 9/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 12/21:55 pm -
1 stop6h 29m
Sat 12/55:40 am -
1 stop9h 26m
Deal found 9/18![Delta logo]()
$363
This Delta deal was found by Cheapflights users on 9/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 12/21:55 pm -
1 stop6h 29m
Tue 12/85:40 am -
2 stops9h 41m
Deal found 9/18![Delta logo]()
$368
This Delta deal was found by Cheapflights users on 9/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 10/251:00 pm -
1 stop6h 08m
Sat 10/315:40 am -
1 stop9h 10m
Deal found 9/16![Delta logo]()
$372
This Delta deal was found by Cheapflights users on 9/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 12/17:39 pm -
2 stops11h 22m
Thu 12/105:40 am -
2 stops9h 35m
Deal found 9/18![Delta logo]()
$374
This Delta deal was found by Cheapflights users on 9/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 12/41:55 pm -
1 stop6h 29m
Sat 12/55:40 am -
1 stop9h 26m
Deal found 9/18![Delta logo]()
$375
This American Airlines deal was found by Cheapflights users on 9/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 10/256:00 am -
1 stop7h 36m
Sat 10/317:30 am -
1 stop7h 20m
Deal found 9/17![American Airlines logo]()
$379
This Delta deal was found by Cheapflights users on 9/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 12/41:16 pm -
1 stop7h 41m
Thu 12/105:40 am -
2 stops9h 35m
Deal found 9/18![Delta logo]()
$380
Best flights from Spokane to KnoxvilleDiscover carefully curated flight deals from Spokane to Knoxville that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated September 21, 2026.
Discover carefully curated flight deals from Spokane to Knoxville that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated September 21, 2026.
This Delta deal was found by Cheapflights users on 9/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 11/271:08 pm -
1 stop6h 04m
Thu 12/35:10 pm -
2 stops9h 47m
Deal found 9/16![Delta logo]()
$339
This United Airlines deal was found by Cheapflights users on 9/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 2/39:00 am -
2 stops12h 05m
Sat 2/65:38 pm -
1 stop7h 45m
Deal found 9/20![United Airlines logo]()
$488
This Delta deal was found by Cheapflights users on 9/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 10/197:25 pm -
2 stops12h 29m
Thu 10/222:38 pm -
2 stops12h 12m
Deal found 9/18![Delta logo]()
$374
This Delta deal was found by Cheapflights users on 9/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 1/812:40 pm -
1 stop8h 06m
Thu 1/147:07 am -
1 stop7h 31m
Deal found 9/18![Delta logo]()
$375
This Delta deal was found by Cheapflights users on 9/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 10/257:25 pm -
2 stops12h 29m
Sat 10/3111:45 am -
2 stops11h 23m
Deal found 9/16![Delta logo]()
$383
This Delta deal was found by Cheapflights users on 9/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 1/712:40 pm -
1 stop8h 06m
Fri 1/1511:30 am -
2 stops15h 12m
Deal found 9/18![Delta logo]()
$420
This Delta deal was found by Cheapflights users on 9/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 3/37:00 am -
2 stops10h 40m
Sun 3/75:30 am -
1 stop9h 08m
Deal found 9/18![Delta logo]()
$420
This Delta deal was found by Cheapflights users on 9/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 10/312:38 pm -
1 stop6h 49m
Tue 10/64:11 pm -
2 stops10h 39m
Deal found 9/16![Delta logo]()
$426
This Delta deal was found by Cheapflights users on 9/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 2/2610:05 am -
2 stops8h 29m
Thu 3/115:15 pm -
2 stops9h 27m
Deal found 9/18![Delta logo]()
$437
Last-minute flights from Spokane to KnoxvilleDiscover last-minute flight deals from Spokane to Knoxville. Data last updated September 21, 2026 and is based on user searches.
Discover last-minute flight deals from Spokane to Knoxville. Data last updated September 21, 2026 and is based on user searches.
This Delta deal was found by Cheapflights users on 9/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 10/1910:50 pm -
1 stop9h 04m
Thu 10/225:40 am -
1 stop9h 10m
Deal found 9/18![Delta logo]()
$363
This Delta deal was found by Cheapflights users on 9/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 10/197:25 pm -
2 stops11h 55m
Wed 10/285:40 am -
2 stops14h 18m
Deal found 9/18![Delta logo]()
$374
This Delta deal was found by Cheapflights users on 9/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 10/1910:50 pm -
1 stop7h 44m
Fri 10/238:35 am -
2 stops11h 23m
Deal found 9/18![Delta logo]()
$380
This Delta deal was found by Cheapflights users on 9/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 10/251:00 pm -
1 stop6h 08m
Sat 10/315:40 am -
1 stop9h 10m
Deal found 9/16![Delta logo]()
$372
This American Airlines deal was found by Cheapflights users on 9/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 10/256:00 am -
1 stop7h 36m
Sat 10/317:30 am -
1 stop7h 20m
Deal found 9/17![American Airlines logo]()
$379
One-way flights from Spokane to KnoxvilleSearch for one-way flight options from Spokane to Knoxville. Find affordable one-way fares based on user searches. Data last updated September 21, 2026.
Search for one-way flight options from Spokane to Knoxville. Find affordable one-way fares based on user searches. Data last updated September 21, 2026.
This Delta deal was found by Cheapflights users on 9/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 10/135:38 pm -
2 stops12h 56m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 9/16![Delta logo]()
$163
This Delta deal was found by Cheapflights users on 9/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 10/147:05 am -
2 stops11h 32m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 9/16![Delta logo]()
$197
This American Airlines deal was found by Cheapflights users on 9/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 10/142:08 pm -
1 stop6h 51m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 9/16![American Airlines logo]()
$274
This American Airlines deal was found by Cheapflights users on 9/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 10/1312:49 pm -
1 stop7h 29m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 9/16![American Airlines logo]()
$277
This American Airlines deal was found by Cheapflights users on 9/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 10/312:45 pm -
1 stop7h 37m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 9/16![American Airlines logo]()
$283
This Delta deal was found by Cheapflights users on 9/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 10/35:14 pm -
2 stops13h 15m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 9/16![Delta logo]()
$288
This Southwest deal was found by Cheapflights users on 9/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 10/136:05 am -
2 stops12h 00m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 9/16![Southwest logo]()
$309
This Southwest deal was found by Cheapflights users on 9/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 10/147:35 am -
2 stops10h 30m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 9/16![Southwest logo]()
$379
This Kiwi.com deal was found by Cheapflights users on 9/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 10/146:03 am -
3 stops38h 18m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 9/16![Multiple Airlines logo]()
$504
This Kiwi.com deal was found by Cheapflights users on 9/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 10/136:03 am -
3 stops25h 59m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 9/16![Multiple Airlines logo]()
$575
This Kiwi.com deal was found by Cheapflights users on 9/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 10/32:51 pm -
3 stops42h 13m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 9/16![Multiple Airlines logo]()
$669
Find flight deals from Spokane to Knoxville
Discover tips and strategies to find the most affordable flight options for your journey from Spokane (GEG) to Knoxville (TYS). Learn about various techniques such as flexible date searches, comparing prices across and setting up price alerts. Use these methods to find the cheapest flights available for your travel needs. Data last updated September 21, 2026.
Most accurate provider | FlightHub 3 stars |
|---|---|
Most trusted provider | FlightHub 3 stars |
Round-trip from | $334 (Delta) |
One-way from | $163 (Delta) |
Popular in | November |
Cheapest in | February |
Average price | $582 |
Cheapflights Fare Finder
Customize your flight search to find flights from Spokane to Knoxville that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 7,457,451 searches. Data last updated September 21, 2026.
Use the filters below to find and compare flights from Spokane to Knoxville that are best for you.
Fly from
Fly to
Route
Depart
Return
Cheapest round-trip
SpokaneKnoxville
GEG Spokane - TYS Knoxville McGhee Tyson
GEGTYS
Spokane
Tue 10/13
5:38 pm-9:34 am
2 stops12h 56m
Knoxville McGhee Tyson
Wed 12/31
12:00 am-9:00 pm
Nonstop0h 00m
$163
Quickest round-trip
SpokaneKnoxville
GEG Spokane - TYS Knoxville McGhee Tyson
GEGTYS
Spokane
Sat 10/3
12:45 pm-11:22 pm
1 stop7h 37m
Knoxville McGhee Tyson
Wed 12/31
12:00 am-9:00 pm
Nonstop0h 00m
$283
SpokaneKnoxville
GEG Spokane - TYS Knoxville McGhee Tyson
GEGTYS
Spokane
Tue 9/29
5:00 am-3:49 pm
1 stop7h 49m
Knoxville McGhee Tyson
Wed 12/31
12:00 am-9:00 pm
Nonstop0h 00m
$283
SpokaneKnoxville
GEG Spokane - TYS Knoxville McGhee Tyson
GEGTYS
Spokane
Tue 9/29
6:15 am-7:00 pm
2 stops9h 45m
Knoxville McGhee Tyson
Wed 12/31
12:00 am-9:00 pm
Nonstop0h 00m
$288
SpokaneKnoxville
GEG Spokane - TYS Knoxville McGhee Tyson
GEGTYS
Spokane
Sat 10/3
5:00 am-8:45 pm
2 stops12h 45m
Knoxville McGhee Tyson
Wed 12/31
12:00 am-9:00 pm
Nonstop0h 00m
$288
SpokaneKnoxville
GEG Spokane - TYS Knoxville McGhee Tyson
GEGTYS
Spokane
Sat 10/3
5:14 pm-9:29 am
2 stops13h 15m
Knoxville McGhee Tyson
Wed 12/31
12:00 am-9:00 pm
Nonstop0h 00m
$288
SpokaneKnoxville
GEG Spokane - TYS Knoxville McGhee Tyson
GEGTYS
Spokane
Fri 11/27
1:08 pm-10:12 pm
1 stop6h 04m
Knoxville McGhee Tyson
Thu 12/3
5:10 pm-11:57 pm
2 stops9h 47m
$339
SpokaneKnoxville
GEG Spokane - TYS Knoxville McGhee Tyson
GEGTYS
Spokane
Mon 10/19
7:25 pm-10:54 am
2 stops12h 29m
Knoxville McGhee Tyson
Thu 10/22
2:38 pm-11:50 pm
2 stops12h 12m
$374
SpokaneKnoxville
GEG Spokane - TYS Knoxville McGhee Tyson
GEGTYS
Spokane
Fri 1/8
12:40 pm-11:46 pm
1 stop8h 06m
Knoxville McGhee Tyson
Thu 1/14
7:07 am-11:38 am
1 stop7h 31m
$375
SpokaneKnoxville
GEG Spokane - TYS Knoxville McGhee Tyson
GEGTYS
Spokane
Wed 10/14
7:35 am-9:05 pm
2 stops10h 30m
Knoxville McGhee Tyson
Wed 12/31
12:00 am-9:00 pm
Nonstop0h 00m
$379
Showing 1-10 of 18 resultsSorted by cheapest first
Compare providers for flights from Spokane to Knoxville
Provider information is updated monthly. Please note that these providers often have deals for this flight, but the availability may vary on a day-by-day basis on Cheapflights.
Use the table below to compare price accuracy, trust ratings, and cancellation policies for each provider offering flight deals from Spokane to Knoxville in September.
| Provider | Price Accuracy | Trust Score* |
|---|---|---|
| Price Accuracy1 star | Trust Score*3 stars | |
| Price Accuracy3 stars | Trust Score*3 stars |
- Most accurate provider: When it comes to deals on Spokane-Knoxville flights, users find the pricing of FlightHub to be most consistent on Cheapflights vs. FlightHub Users can find the same prices on Spokane-Knoxville flight deals on Cheapflights vs. FlightHub >95% of the time. Price accuracy is based on data collected from Spokane-Knoxville flight searches over the past month and is updated monthly.
- Most trusted provider: When it comes to deals on Spokane-Knoxville flights, Cheapflights users trust FlightHub the most. FlightHub has received a user feedback score of 3 out of 3 stars (3 being the best), meaning they have been trusted the most by Cheapflights users looking for Spokane-Knoxville flight deals. Provider user feedback score is based on Cheapflights searches over the past month and is updated monthly.
Best time to book a flight from Spokane to Knoxville
Have a flexible travel schedule? Discover the best time to fly to Knoxville from Spokane with our price prediction graph.
GEG-TYS
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.
Cheapflights Insights
Everything you need to know about your flight from Spokane to Knoxville
What is the cheapest month to book a flight from Spokane to Knoxville?
Currently, February is the cheapest month in which you can book a flight from Spokane to Knoxville (average of $218). Flying from Spokane to Knoxville in November is currently the most expensive (average of $725). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.
How much does it cost to fly round-trip from Spokane to Knoxville?
Airfare is below average for this route at the moment.
Spokane to Knoxville flights typically cost between $562 and $628 in November.The cheapest round-trip price found within the last 5 days was $334 on Delta (Nov 27-Dec 3).
Reviews of airlines servicing Knoxville
Get insights into the airlines that provide service to Knoxville. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Knoxville. Reviews last updated September 21, 2026.
Peruse reviews from past customers who have flown with Delta,United Airlines, andAmerican Airlines from Spokane to Knoxville to help guide your decision. You can also see how each airline stacks up in terms of entertainment options, comfort, food, crew/service, and boarding process.
Food
7.2
Comfort
7.8
Boarding
8.1
Entertainment
7.8
Overall
7.8
Crew
8.5
Reviews
1 / 20
10.0
ExcellentAnonymous,May 2026
SEA - KOA
Food
7.2
Comfort
7.8
Boarding
8.1
Entertainment
7.8
Overall
7.8
Crew
8.5
Reviews
1 / 20
10.0
ExcellentAnonymous,May 2026
SEA - KOA
Food
7.2
Comfort
7.8
Boarding
8.1
Entertainment
7.8
Overall
7.8
Crew
8.5
Reviews
1 / 20
10.0
ExcellentAnonymous,May 2026
SEA - KOA
Food
7.2
Comfort
7.8
Boarding
8.1
Entertainment
7.8
Overall
7.8
Crew
8.5
Reviews
1 / 20
10.0
ExcellentAnonymous,May 2026
SEA - KOA
Related info for your journey
Find useful and relevant information for your journey from Spokane to Knoxville. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.
Traveling to a place near Knoxville?
Book flights to Knoxville if you plan to visit one of these locationsCherokee
Crossville
Morristown
Bryson City
Murphy
Browse thousands of different options on Cheapflights for your next trip
Toggle through the tabs below to find thousands of options on Cheapflights for your next trip.
Alternative routes
Complete your trip
Flights by cabin class
Knoxville flight routes
Other flight options
Other flights from Spokane
Popular flights
Alternative routes for Spokane to Knoxville
See prices for flight routes from nearby airports that may be better suited for you.
Complete your trip
Complete your trip to Knoxville by adding a car rental and/or hotel reservation to your travel itinerary.
Search flights from Spokane to Knoxville by cabin class
Find flights from Spokane to Knoxville, based on your preferred cabin class, be it economy, premium economy, business, or first class.
Other flights to Knoxville
Explore flights to Knoxville departing from other origins. Flights are based on user searches made on Cheapflights and were last updated on September 21, 2026.
Spokane and Knoxville flights
Browse other Spokane and Knoxville flight options. Last updated on September 21, 2026.
Other flights from Spokane
Browse through other flights departing from Spokane. Flights are based on user searches made on Cheapflights and were last updated on September 21, 2026.
Popular flight searches
Check out other popular destinations found by fellow travelers in 2026
Top 3 airlines flying from Spokane to Knoxville
Discover the top 3 airlines that operate flights from Spokane to Knoxville. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 7,457,451 searches. Data last updated September 21, 2026.
| Airline | Cheapest | Average | Flexibility | On-time |
|---|---|---|---|---|
| Cheapest$270 | Average$502 | FlexibilityNo cancel fee | On-time71% | |
| Cheapest$358 | Average$518 | FlexibilityNo cancel fee | On-time69% | |
| Cheapest$397 | Average$526 | FlexibilityNo cancel fee | On-timeN/A |