$141+ Cheap flights from Portland to Knoxville (PDX - TYS)
This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 4/15. Fares are subject to change and may not be available on all flights or dates of travel.
PDX — TYS
Apr 4 — Apr 111
Round-trip
1 adult, Economy
We work with more than 300 partners to bring you better travel deals
Find cheap flights from Portland to Knoxville with Cheapflights
1. Tell us where you want to go
Enter your travel information like dates, passengers, trip type (one-way or round trip), and preferred cabin class then click “Find deals”2. Select your favorite providers
We find the providers serving your travel needs. Choose up to four travel providers to compare side-by-side for flights, hotels, or car rentals.3. Compare prices and book
Review each provider’s pricing and select the best option for you! Book through your favorite provider’s website for a seamless experience.Cheap flight deals from Portland to Knoxville
Cheapest
Best
Last-minute
One-way
Cheapest flights from Portland to KnoxvilleExplore the most affordable flight options available from Portland to Knoxville. Find the lowest fares from popular airlines and budget airlines, with prices last updated on March 5, 2026.
Explore the most affordable flight options available from Portland to Knoxville. Find the lowest fares from popular airlines and budget airlines, with prices last updated on March 5, 2026.
This Kiwi.com deal was found by Cheapflights users on 3/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 4/1812:27 pm
PDX
- TYS
1 stop24h 06m
Multiple Airlines
Mon 4/201:43 pm
TYS
- PDX
2 stops25h 09m
Multiple Airlines
Deal found 3/3![Multiple Airlines logo]()
$241
This Kiwi.com deal was found by Cheapflights users on 2/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 7/93:12 pm
PDX
- TYS
1 stop25h 01m
Frontier
Wed 7/158:08 pm
TYS
- PDX
1 stop18h 05m
Frontier
Deal found 2/28![Frontier logo]()
$305
This Kiwi.com deal was found by Cheapflights users on 2/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 4/58:26 pm
PDX
- TYS
2 stops38h 40m
Multiple Airlines
Mon 4/134:20 pm
TYS
- PDX
1 stop23h 42m
Multiple Airlines
Deal found 2/28![Multiple Airlines logo]()
$344
This Kiwi.com deal was found by Cheapflights users on 3/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 8/203:12 pm
PDX
- TYS
1 stop25h 01m
Frontier
Mon 8/248:08 pm
TYS
- PDX
1 stop18h 05m
Frontier
Deal found 3/2![Frontier logo]()
$358
This Delta deal was found by Cheapflights users on 2/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 4/76:30 am
PDX
- TYS
1 stop6h 36m
Delta
Wed 4/155:26 pm
TYS
- PDX
1 stop7h 16m
Delta
Deal found 2/28![Delta logo]()
$367
This Delta deal was found by Cheapflights users on 2/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 4/76:30 am
PDX
- TYS
1 stop6h 36m
Delta
Sat 4/186:15 am
TYS
- PDX
2 stops9h 02m
Delta
Deal found 2/28![Delta logo]()
$372
This Delta deal was found by Cheapflights users on 2/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 4/611:15 pm
PDX
- TYS
1 stop8h 16m
Delta
Wed 4/155:26 pm
TYS
- PDX
1 stop7h 16m
Delta
Deal found 2/28![Delta logo]()
$376
This Delta deal was found by Cheapflights users on 2/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 4/612:30 am
PDX
- TYS
2 stops13h 13m
Delta
Tue 4/145:26 pm
TYS
- PDX
2 stops9h 30m
Delta
Deal found 2/28![Delta logo]()
$378
This Delta deal was found by Cheapflights users on 2/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 4/611:15 pm
PDX
- TYS
1 stop8h 16m
Delta
Tue 4/145:26 pm
TYS
- PDX
2 stops9h 30m
Delta
Deal found 2/28![Delta logo]()
$381
This American Airlines deal was found by Cheapflights users on 3/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 4/2811:40 pm
PDX
- TYS
1 stop9h 50m
American Airlines
Sat 5/26:00 am
TYS
- PDX
1 stop9h 58m
American Airlines
Deal found 3/3![American Airlines logo]()
$383
Best flights from Portland to KnoxvilleDiscover carefully curated flight deals from Portland to Knoxville that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated March 5, 2026.
Discover carefully curated flight deals from Portland to Knoxville that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated March 5, 2026.
This Delta deal was found by Cheapflights users on 3/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 4/147:32 pm
PDX
- TYS
2 stops11h 49m
Delta
Tue 4/215:26 pm
TYS
- PDX
2 stops9h 30m
Delta
Deal found 3/1![Delta logo]()
$378
This United Airlines deal was found by Cheapflights users on 3/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 4/210:56 pm
PDX
- TYS
1 stop8h 12m
United Airlines
Thu 4/97:05 am
TYS
- PDX
1 stop8h 29m
United Airlines
Deal found 3/4![United Airlines logo]()
$405
This Southwest deal was found by Cheapflights users on 3/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 4/256:00 am
PDX
- TYS
2 stops9h 30m
Southwest
Sat 5/212:20 pm
TYS
- PDX
2 stops12h 25m
Southwest
Deal found 3/4![Southwest logo]()
$461
This Kiwi.com deal was found by Cheapflights users on 3/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 4/212:45 pm
PDX
- TYS
2 stops26h 36m
Multiple Airlines
Thu 4/98:00 am
TYS
- PDX
1 stop13h 56m
Multiple Airlines
Deal found 3/4![Multiple Airlines logo]()
$462
This United Airlines deal was found by Cheapflights users on 2/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 4/1511:59 pm
PDX
- TYS
1 stop7h 09m
United Airlines
Fri 4/174:30 pm
TYS
- PDX
2 stops11h 14m
United Airlines
Deal found 2/28![United Airlines logo]()
$407
This Delta deal was found by Cheapflights users on 3/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 4/247:32 pm
PDX
- TYS
2 stops11h 49m
Delta
Thu 4/305:26 pm
TYS
- PDX
1 stop7h 30m
Delta
Deal found 3/1![Delta logo]()
$437
This United Airlines deal was found by Cheapflights users on 3/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 4/1610:56 pm
PDX
- TYS
1 stop8h 12m
United Airlines
Thu 4/235:53 pm
TYS
- PDX
1 stop9h 06m
United Airlines
Deal found 3/1![United Airlines logo]()
$409
This United Airlines deal was found by Cheapflights users on 3/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 4/2411:59 pm
PDX
- TYS
1 stop7h 07m
United Airlines
Thu 4/305:55 pm
TYS
- PDX
1 stop7h 40m
United Airlines
Deal found 3/1![United Airlines logo]()
$411
This Delta deal was found by Cheapflights users on 3/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 4/211:15 pm
PDX
- TYS
1 stop8h 16m
Delta
Thu 4/97:40 am
TYS
- PDX
2 stops12h 59m
Delta
Deal found 3/4![Delta logo]()
$497
This United Airlines deal was found by Cheapflights users on 3/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 4/1511:59 pm
PDX
- TYS
2 stops12h 10m
United Airlines
Tue 4/211:52 pm
TYS
- PDX
2 stops13h 52m
United Airlines
Deal found 3/1![United Airlines logo]()
$477
This United Airlines deal was found by Cheapflights users on 2/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 4/610:56 pm
PDX
- TYS
2 stops13h 13m
United Airlines
Wed 4/159:40 am
TYS
- PDX
2 stops11h 54m
United Airlines
Deal found 2/28![United Airlines logo]()
$486
Last-minute flights from Portland to KnoxvilleDiscover last-minute flight deals from Portland to Knoxville. Data last updated March 5, 2026 and is based on user searches.
Discover last-minute flight deals from Portland to Knoxville. Data last updated March 5, 2026 and is based on user searches.
This Kiwi.com deal was found by Cheapflights users on 2/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 4/58:26 pm
PDX
- TYS
2 stops38h 40m
Multiple Airlines
Mon 4/134:20 pm
TYS
- PDX
1 stop23h 42m
Multiple Airlines
Deal found 2/28![Multiple Airlines logo]()
$344
This Delta deal was found by Cheapflights users on 2/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 4/611:15 pm
PDX
- TYS
1 stop8h 16m
Delta
Wed 4/155:26 pm
TYS
- PDX
1 stop7h 16m
Delta
Deal found 2/28![Delta logo]()
$376
This Delta deal was found by Cheapflights users on 2/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 4/612:30 am
PDX
- TYS
2 stops13h 13m
Delta
Tue 4/145:26 pm
TYS
- PDX
2 stops9h 30m
Delta
Deal found 2/28![Delta logo]()
$378
This Delta deal was found by Cheapflights users on 2/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 4/611:15 pm
PDX
- TYS
1 stop8h 16m
Delta
Tue 4/145:26 pm
TYS
- PDX
2 stops9h 30m
Delta
Deal found 2/28![Delta logo]()
$381
This Delta deal was found by Cheapflights users on 2/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 4/76:30 am
PDX
- TYS
1 stop6h 36m
Delta
Wed 4/155:26 pm
TYS
- PDX
1 stop7h 16m
Delta
Deal found 2/28![Delta logo]()
$367
This Delta deal was found by Cheapflights users on 2/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 4/76:30 am
PDX
- TYS
1 stop6h 36m
Delta
Sat 4/186:15 am
TYS
- PDX
2 stops9h 02m
Delta
Deal found 2/28![Delta logo]()
$372
This American Airlines deal was found by Cheapflights users on 3/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 4/1411:56 am
PDX
- TYS
1 stop9h 00m
American Airlines
Thu 4/166:00 am
TYS
- PDX
1 stop8h 01m
American Airlines
Deal found 3/3![American Airlines logo]()
$392
This Kiwi.com deal was found by Cheapflights users on 3/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 4/1812:27 pm
PDX
- TYS
1 stop24h 06m
Multiple Airlines
Mon 4/201:43 pm
TYS
- PDX
2 stops25h 09m
Multiple Airlines
Deal found 3/3![Multiple Airlines logo]()
$241
This American Airlines deal was found by Cheapflights users on 3/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 4/2811:40 pm
PDX
- TYS
1 stop9h 50m
American Airlines
Sat 5/26:00 am
TYS
- PDX
1 stop9h 58m
American Airlines
Deal found 3/3![American Airlines logo]()
$383
One-way flights from Portland to KnoxvilleSearch for one-way flight options from Portland to Knoxville. Find affordable one-way fares based on user searches. Data last updated March 5, 2026.
Search for one-way flight options from Portland to Knoxville. Find affordable one-way fares based on user searches. Data last updated March 5, 2026.
This Kiwi.com deal was found by Cheapflights users on 3/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 4/1512:28 pm
PDX
- TYS
3 stops24h 13m
Multiple Airlines
Deal found 3/3![Multiple Airlines logo]()
$141
This Kiwi.com deal was found by Cheapflights users on 3/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 4/2912:38 pm
PDX
- TYS
3 stops30h 55m
Multiple Airlines
Deal found 3/3![Multiple Airlines logo]()
$151
This Kiwi.com deal was found by Cheapflights users on 3/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 3/2712:52 pm
PDX
- TYS
2 stops28h 53m
Multiple Airlines
Deal found 3/4![Multiple Airlines logo]()
$167
This American Airlines deal was found by Cheapflights users on 3/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 4/2911:40 pm
PDX
- TYS
1 stop7h 46m
American Airlines
Deal found 3/1![American Airlines logo]()
$184
This American Airlines deal was found by Cheapflights users on 2/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 4/69:44 pm
PDX
- TYS
1 stop9h 13m
American Airlines
Deal found 2/28![American Airlines logo]()
$193
This United Airlines deal was found by Cheapflights users on 3/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 4/158:40 am
PDX
- TYS
2 stops11h 28m
United Airlines
Deal found 3/3![United Airlines logo]()
$195
This Delta deal was found by Cheapflights users on 3/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 4/611:15 pm
PDX
- TYS
2 stops12h 17m
Delta
Deal found 3/1![Delta logo]()
$198
Find flight deals from Portland to Knoxville
Discover tips and strategies to find the most affordable flight options for your journey from Portland (PDX) to Knoxville (TYS). Learn about various techniques such as flexible date searches, comparing prices across and setting up price alerts. Use these methods to find the cheapest flights available for your travel needs. Data last updated March 5, 2026.
Most accurate provider | FlightHub 3 stars |
|---|---|
Most trusted provider | FlightHub 3 stars |
Round-trip from | $241 (Kiwi.com) |
One-way from | $141 (Kiwi.com) |
Popular in | December |
Cheapest in | August |
Average price | $557 |
Cheapflights Fare Finder
Customize your flight search to find flights from Portland to Knoxville that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated March 5, 2026.
Use the filters below to find and compare flights from Portland to Knoxville that are best for you.
Fly from
Fly to
Route
Depart
Return
PortlandKnoxville
PDX - TYS
PDXTYS
Portland
Tue 4/14
7:32 pm-10:21 am
2 stops11h 49m
Knoxville McGhee Tyson
Tue 4/21
5:26 pm-11:56 pm
2 stops9h 30m
$378
PortlandKnoxville
PDX - TYS
PDXTYS
Portland
Thu 4/2
10:56 pm-10:08 am
1 stop8h 12m
Knoxville McGhee Tyson
Thu 4/9
7:05 am-12:34 pm
1 stop8h 29m
$405
PortlandKnoxville
PDX - TYS
PDXTYS
Portland
Wed 4/15
11:59 pm-10:08 am
1 stop7h 09m
Knoxville McGhee Tyson
Fri 4/17
4:30 pm-12:44 am
2 stops11h 14m
$407
PortlandKnoxville
PDX - TYS
PDXTYS
Portland
Thu 4/16
10:56 pm-10:08 am
1 stop8h 12m
Knoxville McGhee Tyson
Thu 4/23
5:53 pm-11:59 pm
1 stop9h 06m
$409
PortlandKnoxville
PDX - TYS
PDXTYS
Portland
Fri 4/24
11:59 pm-10:06 am
1 stop7h 07m
Knoxville McGhee Tyson
Thu 4/30
5:55 pm-10:35 pm
1 stop7h 40m
$411
PortlandKnoxville
PDX - TYS
PDXTYS
Portland
Fri 4/24
7:32 pm-10:21 am
2 stops11h 49m
Knoxville McGhee Tyson
Thu 4/30
5:26 pm-9:56 pm
1 stop7h 30m
$437
PortlandKnoxville
PDX - TYS
PDXTYS
Portland
Sat 4/25
6:00 am-6:30 pm
2 stops9h 30m
Knoxville McGhee Tyson
Sat 5/2
12:20 pm-9:45 pm
2 stops12h 25m
$461
PortlandKnoxville
PDX - TYS
PDXTYS
Portland
Thu 4/2
12:45 pm-6:21 pm
2 stops26h 36m
Knoxville McGhee Tyson
Thu 4/9
8:00 am-6:56 pm
1 stop13h 56m
$462
PortlandKnoxville
PDX - TYS
PDXTYS
Portland
Wed 4/15
11:59 pm-3:09 pm
2 stops12h 10m
Knoxville McGhee Tyson
Tue 4/21
1:52 pm-12:44 am
2 stops13h 52m
$477
PortlandKnoxville
PDX - TYS
PDXTYS
Portland
Mon 4/6
10:56 pm-3:09 pm
2 stops13h 13m
Knoxville McGhee Tyson
Wed 4/15
9:40 am-6:34 pm
2 stops11h 54m
$486
Showing 1-10 of 18 resultsSorted by cheapest first
Compare providers for flights from Portland to Knoxville
Provider information is updated monthly. Please note that these providers often have deals for this flight, but the availability may vary on a day-by-day basis on Cheapflights.
Use the table below to compare price accuracy, trust ratings, and cancellation policies for each provider offering flight deals from Portland to Knoxville in March.
| Provider | Price Accuracy | Trust Score* |
|---|---|---|
| Price Accuracy1 star | Trust Score*3 stars | |
| Price Accuracy3 stars | Trust Score*3 stars |
- Most accurate provider: When it comes to deals on Portland-Knoxville flights, users find the pricing of FlightHub to be most consistent on Cheapflights vs. FlightHub Users can find the same prices on Portland-Knoxville flight deals on Cheapflights vs. FlightHub >95% of the time. Price accuracy is based on data collected from Portland-Knoxville flight searches over the past month and is updated monthly.
- Most trusted provider: When it comes to deals on Portland-Knoxville flights, Cheapflights users trust FlightHub the most. FlightHub has received a user feedback score of 3 out of 3 stars (3 being the best), meaning they have been trusted the most by Cheapflights users looking for Portland-Knoxville flight deals. Provider user feedback score is based on Cheapflights searches over the past month and is updated monthly.
Best time to book a flight from Portland to Knoxville
Have a flexible travel schedule? Discover the best time to fly to Knoxville from Portland with our price prediction graph.
PDX-TYS
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.
Cheapflights Insights
Everything you need to know about your flight from Portland to Knoxville
How far ahead should I book a flight from Portland to Knoxville?
Use this chart to determine the optimal time to book a round-trip flight from Portland to Knoxville. Price data was last updated on February 27, 2026.
The best time to book flights from Portland to Knoxville is 75 days before your desired departure date. The cost of your flight will likely increase significantly if you book two weeks in advance of your flight.
What is the cheapest month to book a flight from Portland to Knoxville?
Currently, July is the cheapest month in which you can book a flight from Portland to Knoxville (average of $126). Flying from Portland to Knoxville in May is currently the most expensive (average of $286). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.
Reviews of airlines servicing Knoxville
Get insights into the airlines that provide service to Knoxville. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Knoxville. Reviews last updated March 5, 2026.
Read through reviews of airlines operating flights from Portland to Knoxville, such as Delta, United Airlines, and American Airlines. Reviews also offer insight into each airline's entertainment options, comfort, food, crew/service, and boarding process.
Boarding
8.1
Crew
8.5
Entertainment
7.8
Comfort
7.9
Overall
7.9
Food
7.2
Reviews
1 / 20
6.0
GoodJim,Nov 2025
AVL - ATL
Boarding
8.1
Crew
8.5
Entertainment
7.8
Comfort
7.9
Overall
7.9
Food
7.2
Reviews
1 / 20
6.0
GoodJim,Nov 2025
AVL - ATL
Boarding
8.1
Crew
8.5
Entertainment
7.8
Comfort
7.9
Overall
7.9
Food
7.2
Reviews
1 / 20
6.0
GoodJim,Nov 2025
AVL - ATL
Boarding
8.1
Crew
8.5
Entertainment
7.8
Comfort
7.9
Overall
7.9
Food
7.2
Reviews
1 / 20
6.0
GoodJim,Nov 2025
AVL - ATL
Boarding
8.1
Crew
8.5
Entertainment
7.8
Comfort
7.9
Overall
7.9
Food
7.2
Reviews
1 / 20
6.0
GoodJim,Nov 2025
AVL - ATL
Related info for your journey
Find useful and relevant information for your journey from Portland to Knoxville. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.
Traveling to a place near Knoxville?
Book flights to Knoxville if you plan to visit one of these locationsCherokee
Crossville
Corbin
Morristown
Bryson City
Alcoa
Murphy
Oak Ridge
Browse thousands of different options on Cheapflights for your next trip
Toggle through the tabs below to find thousands of options on Cheapflights for your next trip.
Alternative routes
Complete your trip
Flights by cabin class
Knoxville flight routes
Other flight options
Other flights from Portland
Popular flights
Alternative routes for Portland to Knoxville
See prices for flight routes from nearby airports that may be better suited for you.
Complete your trip
Complete your trip to Knoxville by adding a car rental and/or hotel reservation to your travel itinerary.
Search flights from Portland to Knoxville by cabin class
Find flights from Portland to Knoxville, based on your preferred cabin class, be it economy, premium economy, business, or first class.
Other flights to Knoxville
Explore flights to Knoxville departing from other origins. Flights are based on user searches made on Cheapflights and were last updated on March 5, 2026.
Portland and Knoxville flights
Browse other Portland and Knoxville flight options. Last updated on March 5, 2026.
Other flights from Portland
Browse through other flights departing from Portland. Flights are based on user searches made on Cheapflights and were last updated on March 5, 2026.
Popular flight searches
Check out other popular destinations found by fellow travelers in 2026
Top 4 airlines flying from Portland to Knoxville
Discover the top 4 airlines that operate flights from Portland to Knoxville. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated March 5, 2026.
| Airline | Cheapest | Average | Flexibility | On-time |
|---|---|---|---|---|
| Cheapest$240 | Average$326 | FlexibilityNo cancel fee | On-time62% | |
| Cheapest$248 | Average$465 | FlexibilityNo cancel fee | On-time69% | |
| Cheapest$268 | Average$429 | FlexibilityNo cancel fee | On-timeN/A | |
| Cheapest$284 | Average$447 | FlexibilityNo cancel fee | On-time71% |