$127+ Cheap flights from Portland to Knoxville (PDX - TYS)
This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 6/9. Fares are subject to change and may not be available on all flights or dates of travel.
PDX — TYS
Jun 19 — Jun 261
Round-trip
1 adult, Economy
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Cheapest flights from Portland to KnoxvilleExplore the most affordable flight options available from Portland to Knoxville. Find the lowest fares from popular airlines and budget airlines, with prices last updated on May 20, 2026.
Explore the most affordable flight options available from Portland to Knoxville. Find the lowest fares from popular airlines and budget airlines, with prices last updated on May 20, 2026.
This Kiwi.com deal was found by Cheapflights users on 5/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/229:34 pm
PDX
- TYS
1 stop21h 15m
Multiple Airlines
Thu 10/296:30 am
TYS
- PDX
1 stop13h 05m
Multiple Airlines
Deal found 5/15![Multiple Airlines logo]()
$376
This American Airlines deal was found by Cheapflights users on 5/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 6/812:40 am
PDX
- TYS
1 stop9h 22m
American Airlines
Tue 6/235:33 pm
TYS
- PDX
1 stop10h 17m
American Airlines
Deal found 5/19![American Airlines logo]()
$395
This Kiwi.com deal was found by Cheapflights users on 5/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 8/225:42 pm
PDX
- TYS
2 stops17h 07m
Multiple Airlines
Thu 8/277:00 am
TYS
- PDX
1 stop12h 57m
Multiple Airlines
Deal found 5/16![Multiple Airlines logo]()
$404
This Booking.com deal was found by Cheapflights users on 5/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Booking.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 6/165:20 pm
PDX
- TYS
1 stop23h 17m
Frontier
Mon 6/228:32 pm
TYS
- PDX
1 stop23h 03m
Frontier
Deal found 5/16![Frontier logo]()
$412
This American Airlines deal was found by Cheapflights users on 5/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 9/125:20 am
PDX
- TYS
1 stop8h 25m
American Airlines
Tue 9/225:37 pm
TYS
- PDX
1 stop7h 20m
American Airlines
Deal found 5/19![American Airlines logo]()
$416
This Kiwi.com deal was found by Cheapflights users on 5/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 7/412:26 pm
PDX
- TYS
1 stop22h 25m
Multiple Airlines
Fri 7/177:04 pm
TYS
- PDX
2 stops40h 03m
Multiple Airlines
Deal found 5/15![Multiple Airlines logo]()
$417
This United Airlines deal was found by Cheapflights users on 5/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 8/2510:56 am
PDX
- TYS
2 stops10h 03m
United Airlines
Sat 8/297:15 am
TYS
- PDX
1 stop7h 44m
United Airlines
Deal found 5/16![United Airlines logo]()
$421
This Kiwi.com deal was found by Cheapflights users on 5/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 6/110:31 am
PDX
- TYS
2 stops21h 10m
Multiple Airlines
Thu 6/257:00 am
TYS
- PDX
1 stop12h 57m
Multiple Airlines
Deal found 5/18![Multiple Airlines logo]()
$423
This Delta deal was found by Cheapflights users on 5/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 8/2611:45 am
PDX
- TYS
1 stop9h 07m
Delta
Sun 8/305:19 am
TYS
- PDX
1 stop8h 09m
Delta
Deal found 5/16![Delta logo]()
$426
This Kiwi.com deal was found by Cheapflights users on 5/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 8/236:19 pm
PDX
- TYS
1 stop24h 27m
Multiple Airlines
Thu 8/277:00 am
TYS
- PDX
1 stop12h 57m
Multiple Airlines
Deal found 5/16![Multiple Airlines logo]()
$427
Best flights from Portland to KnoxvilleDiscover carefully curated flight deals from Portland to Knoxville that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated May 20, 2026.
Discover carefully curated flight deals from Portland to Knoxville that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated May 20, 2026.
This Delta deal was found by Cheapflights users on 5/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 6/2911:15 pm
PDX
- TYS
1 stop8h 12m
Delta
Fri 7/36:42 pm
TYS
- PDX
1 stop7h 36m
Delta
Deal found 5/19![Delta logo]()
$457
This United Airlines deal was found by Cheapflights users on 5/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 6/2311:30 pm
PDX
- TYS
1 stop8h 12m
United Airlines
Tue 7/146:00 am
TYS
- PDX
1 stop8h 38m
United Airlines
Deal found 5/18![United Airlines logo]()
$467
This American Airlines deal was found by Cheapflights users on 5/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 7/2110:57 pm
PDX
- TYS
1 stop9h 08m
American Airlines
Sun 7/268:11 pm
TYS
- PDX
1 stop7h 44m
American Airlines
Deal found 5/15![American Airlines logo]()
$497
This Alaska Airlines deal was found by Cheapflights users on 5/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Alaska Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 6/2910:59 pm
PDX
- TYS
1 stop8h 59m
Alaska Airlines
Fri 7/31:00 pm
TYS
- PDX
2 stops12h 25m
Alaska Airlines
Deal found 5/19![Alaska Airlines logo]()
$572
This Southwest deal was found by Cheapflights users on 5/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 6/306:00 am
PDX
- TYS
2 stops11h 20m
Southwest
Sat 7/48:00 am
TYS
- PDX
2 stops12h 30m
Southwest
Deal found 5/19![Southwest logo]()
$577
This Delta deal was found by Cheapflights users on 5/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 6/2911:15 pm
PDX
- TYS
1 stop8h 12m
Delta
Sat 7/46:45 am
TYS
- PDX
1 stop6h 55m
Delta
Deal found 5/19![Delta logo]()
$457
This Delta deal was found by Cheapflights users on 5/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 7/2111:37 am
PDX
- TYS
1 stop9h 15m
Delta
Sun 7/2611:55 am
TYS
- PDX
1 stop10h 01m
Delta
Deal found 5/17![Delta logo]()
$468
This Alaska Airlines deal was found by Cheapflights users on 5/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Alaska Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 7/97:17 am
PDX
- TYS
1 stop9h 43m
Alaska Airlines
Wed 7/151:00 pm
TYS
- PDX
2 stops13h 30m
Alaska Airlines
Deal found 5/17![Alaska Airlines logo]()
$572
This Delta deal was found by Cheapflights users on 5/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 7/302:08 pm
PDX
- TYS
1 stop6h 44m
Delta
Mon 8/36:30 am
TYS
- PDX
1 stop10h 08m
Delta
Deal found 5/19![Delta logo]()
$478
This Alaska Airlines deal was found by Cheapflights users on 5/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Alaska Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 6/308:19 am
PDX
- TYS
2 stops12h 34m
Alaska Airlines
Wed 7/151:00 pm
TYS
- PDX
2 stops13h 30m
Alaska Airlines
Deal found 5/15![Alaska Airlines logo]()
$577
This Delta deal was found by Cheapflights users on 5/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 5/272:06 pm
PDX
- TYS
1 stop6h 55m
Delta
Sat 5/305:40 am
TYS
- PDX
1 stop7h 31m
Delta
Deal found 5/17![Delta logo]()
$595
Last-minute flights from Portland to KnoxvilleDiscover last-minute flight deals from Portland to Knoxville. Data last updated May 20, 2026 and is based on user searches.
Discover last-minute flight deals from Portland to Knoxville. Data last updated May 20, 2026 and is based on user searches.
This Delta deal was found by Cheapflights users on 5/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 5/2711:12 pm
PDX
- TYS
1 stop8h 09m
Delta
Fri 5/293:30 pm
TYS
- PDX
1 stop9h 16m
Delta
Deal found 5/18![Delta logo]()
$457
This United Airlines deal was found by Cheapflights users on 5/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 5/2711:05 am
PDX
- TYS
2 stops9h 07m
United Airlines
Fri 5/296:30 am
TYS
- PDX
1 stop8h 08m
United Airlines
Deal found 5/18![United Airlines logo]()
$502
This Booking.com deal was found by Cheapflights users on 5/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Booking.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 5/2812:35 pm
PDX
- TYS
1 stop27h 49m
Frontier
Mon 6/18:32 pm
TYS
- PDX
1 stop23h 29m
Frontier
Deal found 5/18![Frontier logo]()
$460
This Kiwi.com deal was found by Cheapflights users on 5/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 6/110:31 am
PDX
- TYS
2 stops21h 10m
Multiple Airlines
Thu 6/257:00 am
TYS
- PDX
1 stop12h 57m
Multiple Airlines
Deal found 5/18![Multiple Airlines logo]()
$423
This American Airlines deal was found by Cheapflights users on 5/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 6/812:40 am
PDX
- TYS
1 stop9h 22m
American Airlines
Tue 6/235:33 pm
TYS
- PDX
1 stop10h 17m
American Airlines
Deal found 5/19![American Airlines logo]()
$395
This American Airlines deal was found by Cheapflights users on 5/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 6/1512:40 am
PDX
- TYS
1 stop9h 22m
American Airlines
Tue 6/235:33 pm
TYS
- PDX
1 stop8h 18m
American Airlines
Deal found 5/19![American Airlines logo]()
$497
This Booking.com deal was found by Cheapflights users on 5/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Booking.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 6/165:20 pm
PDX
- TYS
1 stop23h 17m
Frontier
Mon 6/228:32 pm
TYS
- PDX
1 stop23h 03m
Frontier
Deal found 5/16![Frontier logo]()
$412
This United Airlines deal was found by Cheapflights users on 5/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 6/2311:30 pm
PDX
- TYS
1 stop8h 12m
United Airlines
Tue 7/146:00 am
TYS
- PDX
1 stop8h 38m
United Airlines
Deal found 5/18![United Airlines logo]()
$467
This American Airlines deal was found by Cheapflights users on 5/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 6/2912:40 am
PDX
- TYS
1 stop9h 22m
American Airlines
Sat 7/41:43 pm
TYS
- PDX
1 stop10h 17m
American Airlines
Deal found 5/19![American Airlines logo]()
$426
This Kiwi.com deal was found by Cheapflights users on 5/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 6/305:20 pm
PDX
- TYS
1 stop23h 17m
Frontier
Fri 7/38:32 pm
TYS
- PDX
1 stop23h 25m
Frontier
Deal found 5/19![Frontier logo]()
$482
One-way flights from Portland to KnoxvilleSearch for one-way flight options from Portland to Knoxville. Find affordable one-way fares based on user searches. Data last updated May 20, 2026.
Search for one-way flight options from Portland to Knoxville. Find affordable one-way fares based on user searches. Data last updated May 20, 2026.
This Kiwi.com deal was found by Cheapflights users on 5/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 6/95:20 pm
PDX
- TYS
1 stop23h 17m
Frontier
Deal found 5/18![Frontier logo]()
$127
This Kiwi.com deal was found by Cheapflights users on 5/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 8/125:16 pm
PDX
- TYS
1 stop17h 45m
Multiple Airlines
Deal found 5/19![Multiple Airlines logo]()
$130
This Kiwi.com deal was found by Cheapflights users on 5/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 7/75:16 pm
PDX
- TYS
1 stop23h 20m
Frontier
Deal found 5/18![Frontier logo]()
$163
This United Airlines deal was found by Cheapflights users on 5/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 7/2210:40 pm
PDX
- TYS
1 stop8h 03m
United Airlines
Deal found 5/15![United Airlines logo]()
$198
This Kiwi.com deal was found by Cheapflights users on 5/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 6/72:38 pm
PDX
- TYS
3 stops28h 12m
Multiple Airlines
Deal found 5/18![Multiple Airlines logo]()
$203
This Gotogate deal was found by Cheapflights users on 5/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Gotogate is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 7/2312:26 pm
PDX
- TYS
1 stop28h 10m
Frontier
Deal found 5/15![Frontier logo]()
$206
This Kiwi.com deal was found by Cheapflights users on 5/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 8/145:42 pm
PDX
- TYS
2 stops41h 19m
Multiple Airlines
Deal found 5/16![Multiple Airlines logo]()
$218
This Delta deal was found by Cheapflights users on 5/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 7/2311:15 pm
PDX
- TYS
1 stop8h 05m
Delta
Deal found 5/15![Delta logo]()
$219
This Booking.com deal was found by Cheapflights users on 5/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Booking.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 6/712:35 pm
PDX
- TYS
1 stop27h 58m
Frontier
Deal found 5/19![Frontier logo]()
$222
This Kiwi.com deal was found by Cheapflights users on 5/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 8/76:59 pm
PDX
- TYS
2 stops24h 04m
Multiple Airlines
Deal found 5/18![Multiple Airlines logo]()
$223
This Kiwi.com deal was found by Cheapflights users on 5/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 8/166:59 pm
PDX
- TYS
2 stops21h 37m
Frontier
Deal found 5/16![Frontier logo]()
$224
Find flight deals from Portland to Knoxville
Discover tips and strategies to find the most affordable flight options for your journey from Portland (PDX) to Knoxville (TYS). Learn about various techniques such as flexible date searches, comparing prices across and setting up price alerts. Use these methods to find the cheapest flights available for your travel needs. Data last updated May 20, 2026.
Most accurate provider | FlightHub 3 stars |
|---|---|
Most trusted provider | FlightHub 3 stars |
Round-trip from | $376 (Kiwi.com) |
One-way from | $127 (Kiwi.com) |
Popular in | March |
Cheapest in | August |
Average price | $505 |
Cheapflights Fare Finder
Customize your flight search to find flights from Portland to Knoxville that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated May 20, 2026.
Use the filters below to find and compare flights from Portland to Knoxville that are best for you.
Fly from
Fly to
Route
Depart
Return
Cheapest round-trip
PortlandKnoxville
PDX - TYS
PDXTYS
Portland
Mon 6/29
11:15 pm-10:27 am
1 stop8h 12m
Knoxville McGhee Tyson
Fri 7/3
6:42 pm-11:18 pm
1 stop7h 36m
$457
PortlandKnoxville
PDX - TYS
PDXTYS
Portland
Mon 6/29
11:15 pm-10:27 am
1 stop8h 12m
Knoxville McGhee Tyson
Sat 7/4
6:45 am-10:40 am
1 stop6h 55m
$457
PortlandKnoxville
PDX - TYS
PDXTYS
Portland
Tue 6/23
11:30 pm-10:42 am
1 stop8h 12m
Knoxville McGhee Tyson
Tue 7/14
6:00 am-11:38 am
1 stop8h 38m
$467
PortlandKnoxville
PDX - TYS
PDXTYS
Portland
Tue 7/21
11:37 am-11:52 pm
1 stop9h 15m
Knoxville McGhee Tyson
Sun 7/26
11:55 am-6:56 pm
1 stop10h 01m
$468
PortlandKnoxville
PDX - TYS
PDXTYS
Portland
Thu 7/30
2:08 pm-11:52 pm
1 stop6h 44m
Knoxville McGhee Tyson
Mon 8/3
6:30 am-1:38 pm
1 stop10h 08m
$478
PortlandKnoxville
PDX - TYS
PDXTYS
Portland
Tue 7/21
10:57 pm-11:05 am
1 stop9h 08m
Knoxville McGhee Tyson
Sun 7/26
8:11 pm-12:55 am
1 stop7h 44m
$497
PortlandKnoxville
PDX - TYS
PDXTYS
Portland
Mon 6/29
10:59 pm-10:58 am
1 stop8h 59m
Knoxville McGhee Tyson
Fri 7/3
1:00 pm-10:25 pm
2 stops12h 25m
$572
PortlandKnoxville
PDX - TYS
PDXTYS
Portland
Thu 7/9
7:17 am-8:00 pm
1 stop9h 43m
Knoxville McGhee Tyson
Wed 7/15
1:00 pm-11:30 pm
2 stops13h 30m
$572
PortlandKnoxville
PDX - TYS
PDXTYS
Portland
Tue 6/30
6:00 am-8:20 pm
2 stops11h 20m
Knoxville McGhee Tyson
Sat 7/4
8:00 am-5:30 pm
2 stops12h 30m
$577
PortlandKnoxville
PDX - TYS
PDXTYS
Portland
Tue 6/30
8:19 am-11:53 pm
2 stops12h 34m
Knoxville McGhee Tyson
Wed 7/15
1:00 pm-11:30 pm
2 stops13h 30m
$577
Showing 1-10 of 18 resultsSorted by cheapest first
Compare providers for flights from Portland to Knoxville
Provider information is updated monthly. Please note that these providers often have deals for this flight, but the availability may vary on a day-by-day basis on Cheapflights.
Use the table below to compare price accuracy, trust ratings, and cancellation policies for each provider offering flight deals from Portland to Knoxville in May.
| Provider | Price Accuracy | Trust Score* |
|---|---|---|
| Price Accuracy1 star | Trust Score*3 stars | |
| Price Accuracy3 stars | Trust Score*3 stars |
- Most accurate provider: When it comes to deals on Portland-Knoxville flights, users find the pricing of FlightHub to be most consistent on Cheapflights vs. FlightHub Users can find the same prices on Portland-Knoxville flight deals on Cheapflights vs. FlightHub >95% of the time. Price accuracy is based on data collected from Portland-Knoxville flight searches over the past month and is updated monthly.
- Most trusted provider: When it comes to deals on Portland-Knoxville flights, Cheapflights users trust FlightHub the most. FlightHub has received a user feedback score of 3 out of 3 stars (3 being the best), meaning they have been trusted the most by Cheapflights users looking for Portland-Knoxville flight deals. Provider user feedback score is based on Cheapflights searches over the past month and is updated monthly.
Best time to book a flight from Portland to Knoxville
Have a flexible travel schedule? Discover the best time to fly to Knoxville from Portland with our price prediction graph.
PDX-TYS
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.
Cheapflights Insights
Everything you need to know about your flight from Portland to Knoxville
How far ahead should I book a flight from Portland to Knoxville?
The best time to book flights from Portland to Knoxville is 74 days before your desired departure date. The cost of your flight will likely increase significantly if you book two weeks in advance of your flight.
What is the cheapest month to book a flight from Portland to Knoxville?
Currently, August is the cheapest month in which you can book a flight from Portland to Knoxville (average of $388). Flying from Portland to Knoxville in March is currently the most expensive (average of $569). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.
How much does it cost to fly round-trip from Portland to Knoxville?
Reviews of airlines servicing Knoxville
Get insights into the airlines that provide service to Knoxville. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Knoxville. Reviews last updated May 20, 2026.
Read through reviews of airlines operating flights from Portland to Knoxville, such as Delta,United Airlines, andAmerican Airlines. Reviews also offer insight into each airline's entertainment options, comfort, food, crew/service, and boarding process.
Food
7.2
Entertainment
7.8
Overall
7.9
Crew
8.5
Boarding
8.1
Comfort
7.8
Reviews
1 / 20
10.0
ExcellentAnonymous,May 2026
SEA - KOA
Food
7.2
Entertainment
7.8
Overall
7.9
Crew
8.5
Boarding
8.1
Comfort
7.8
Reviews
1 / 20
10.0
ExcellentAnonymous,May 2026
SEA - KOA
Food
7.2
Entertainment
7.8
Overall
7.9
Crew
8.5
Boarding
8.1
Comfort
7.8
Reviews
1 / 20
10.0
ExcellentAnonymous,May 2026
SEA - KOA
Food
7.2
Entertainment
7.8
Overall
7.9
Crew
8.5
Boarding
8.1
Comfort
7.8
Reviews
1 / 20
10.0
ExcellentAnonymous,May 2026
SEA - KOA
Food
7.2
Entertainment
7.8
Overall
7.9
Crew
8.5
Boarding
8.1
Comfort
7.8
Reviews
1 / 20
10.0
ExcellentAnonymous,May 2026
SEA - KOA
Related info for your journey
Find useful and relevant information for your journey from Portland to Knoxville. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.
Traveling to a place near Knoxville?
Book flights to Knoxville if you plan to visit one of these locationsCherokee
Crossville
Morristown
Bryson City
Murphy
Alcoa
Oak Ridge
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Other flights to Knoxville
Explore flights to Knoxville departing from other origins. Flights are based on user searches made on Cheapflights and were last updated on May 20, 2026.
Portland and Knoxville flights
Browse other Portland and Knoxville flight options. Last updated on May 20, 2026.
Other flights from Portland
Browse through other flights departing from Portland. Flights are based on user searches made on Cheapflights and were last updated on May 20, 2026.
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Check out other popular destinations found by fellow travelers in 2026
Top 4 airlines flying from Portland to Knoxville
Discover the top 4 airlines that operate flights from Portland to Knoxville. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated May 20, 2026.
| Airline | Cheapest | Average | Flexibility | On-time |
|---|---|---|---|---|
| Cheapest$256 | Average$476 | FlexibilityNo cancel fee | On-timeN/A | |
| Cheapest$264 | Average$343 | FlexibilityNo cancel fee | On-time62% | |
| Cheapest$279 | Average$498 | FlexibilityNo cancel fee | On-time69% | |
| Cheapest$308 | Average$457 | FlexibilityNo cancel fee | On-time71% |