How long is the flight from Portland to Knoxville?

For as low as $359, Delta can have you in Knoxville from Portland in 8h 46m. There are 2107 mi between Portland and Knoxville.

What are the cheapest airlines flying from Portland to Knoxville round-trip?

Cheapflights users have booked flights from Portland to Knoxville round-trip from $240. Other airlines that can offer you cheap pricing are United Airlines, from $248, and Delta, from $278. Frontier is 46% cheaper than the average price of flights available within the next 90 days to this destination.

What are the cheapest airlines to fly from Portland to Knoxville one-way?

The cheapest airline one-way is Frontier, with whom users have recently found tickets for as low as $107. However, be on the lookout for offers from American Airlines and Delta, as they are both options that can get you from Portland to Knoxville for a low price.

In terms of precipitation, rainfall in Knoxville ranges from 2.7 - 4.8 inches per month. March is typically the wettest month, when rainfall can reach 4.8 in. October is typically the driest time to visit Knoxville when rainfall is around 2.7 in.

If weather is an important factor for your trip to Knoxville, use this chart to help with planning. For those seeking warmer temperatures, July is the ideal time of year to visit, when temperatures reach an average of 78.8 F. Travelers looking to avoid the cold should look outside of January, when temperatures are typically at their lowest (around 39.2 F).

What are the most popular airlines that fly from Portland to Knoxville?

Consider American Airlines, Delta or United Airlines when booking your flight. These represent the most popular airlines when flying from Portland to Knoxville.

What is the cheapest time of day to fly from PDX to TYS?

When flying from Portland to Knoxville, the time of day you decide to fly out makes little to no difference towards the overall price you’ll pay on tickets.

Most accurate provider : When it comes to deals on Portland-Knoxville flights, users find the pricing of eDreams to be most consistent on Cheapflights vs. eDreams Users can find the same prices on Portland-Knoxville flight deals on Cheapflights vs. eDreams >95% of the time. Price accuracy is based on data collected from Portland-Knoxville flight searches over the past month and is updated monthly.

Most trusted provider : When it comes to deals on Portland-Knoxville flights, Cheapflights users trust eDreams the most. eDreams has received a user feedback score of 3 out of 3 stars (3 being the best), meaning they have been trusted the most by Cheapflights users looking for Portland-Knoxville flight deals. Provider user feedback score is based on Cheapflights searches over the past month and is updated monthly.

Can I find deals for flights from Portland to Knoxville that include hotel bookings?

Yes. In addition to deals on Portland to Knoxville flights, Cheapflights offers vacation packages that include both flights and hotel.

How can I find direct flights from Portland to Knoxville?

After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Portland to Knoxville.

Can I find deals for business class flights from Portland to Knoxville?

Yes. Cheapflights offers flight deals from Portland to Knoxville by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

$151+ Flights from Portland to Knoxville

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Cheap flight deals from Portland to Knoxville

Cheapest flights from Portland to Knoxville
Explore the most affordable flight options available from Portland to Knoxville. Find the lowest fares from popular airlines and budget airlines, with prices last updated on December 30, 2025.

Tue 12/3010:21 pmPDX - TYS

1 stop7h 35mAmerican Airlines

Wed 1/76:00 amTYS - PDX

1 stop8h 45mAmerican Airlines

Deal found 12/28

$710

Mon 12/297:45 pmPDX - TYS

2 stops12h 26mUnited Airlines

Wed 1/711:10 amTYS - PDX

2 stops10h 00mUnited Airlines

Deal found 12/29

$820

Best flights from Portland to Knoxville
Discover carefully curated flight deals from Portland to Knoxville that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated December 30, 2025.

Tue 1/2711:59 amPDX - TYS

1 stop8h 46mDelta

Wed 2/46:30 amTYS - PDX

1 stop9h 16mDelta

Deal found 12/28

$359

Sat 1/3111:44 amPDX - TYS

1 stop9h 01mDelta

Wed 2/46:30 amTYS - PDX

1 stop9h 16mDelta

Deal found 12/28

$363

Tue 1/279:45 pmPDX - TYS

1 stop8h 36mDelta

Tue 2/310:07 amTYS - PDX

2 stops10h 28mDelta

Deal found 12/28

$364

Thu 1/291:53 pmPDX - TYS

1 stop6h 16mDelta

Sat 2/76:30 amTYS - PDX

1 stop9h 16mDelta

Deal found 12/28

$376

Mon 1/267:37 pmPDX - TYS

2 stops10h 44mDelta

Tue 2/35:40 amTYS - PDX

1 stop8h 07mDelta

Deal found 12/28

$377

Mon 1/269:45 pmPDX - TYS

1 stop8h 36mDelta

Wed 2/47:30 amTYS - PDX

2 stops13h 05mDelta

Deal found 12/28

$377

Tue 1/275:00 pmPDX - TYS

2 stops13h 21mDelta

Mon 2/211:58 amTYS - PDX

2 stops11h 34mDelta

Deal found 12/28

$382

Wed 1/286:00 amPDX - TYS

2 stops11h 47mDelta

Thu 2/57:30 amTYS - PDX

2 stops13h 05mDelta

Deal found 12/28

$382

Mon 1/261:53 pmPDX - TYS

1 stop6h 16mDelta

Thu 2/55:40 amTYS - PDX

1 stop8h 07mDelta

Deal found 12/28

$385

Mon 1/269:45 pmPDX - TYS

1 stop8h 36mDelta

Mon 2/211:58 amTYS - PDX

2 stops11h 34mDelta

Deal found 12/28

$390

Last-minute flights from Portland to Knoxville
Discover last-minute flight deals from Portland to Knoxville. Data last updated December 30, 2025 and is based on user searches.

Sat 1/249:45 pmPDX - TYS

1 stop8h 36mDelta

Sat 1/315:40 amTYS - PDX

1 stop7h 54mDelta

Deal found 12/28

$367

Mon 1/261:53 pmPDX - TYS

1 stop6h 16mDelta

Sat 2/76:30 amTYS - PDX

1 stop9h 16mDelta

Deal found 12/28

$376

Wed 1/289:45 pmPDX - TYS

1 stop8h 36mDelta

Tue 2/36:30 amTYS - PDX

1 stop9h 16mDelta

Deal found 12/28

$359

Thu 1/2911:28 amPDX - TYS

1 stop26h 22mMultiple Airlines

Fri 2/67:35 amTYS - PDX

2 stops15h 52mMultiple Airlines

Deal found 12/28

$338

Thu 1/2911:28 amPDX - TYS

1 stop26h 22mMultiple Airlines

Mon 2/27:35 amTYS - PDX

2 stops15h 52mMultiple Airlines

Deal found 12/28

$341

Thu 1/2911:28 amPDX - TYS

1 stop26h 22mMultiple Airlines

Thu 2/510:00 amTYS - PDX

2 stops26h 49mMultiple Airlines

Deal found 12/28

$356

Sat 1/3111:44 amPDX - TYS

1 stop9h 01mDelta

Wed 2/46:30 amTYS - PDX

1 stop9h 16mDelta

Deal found 12/28

$363

Sat 1/3111:44 amPDX - TYS

1 stop9h 01mDelta

Tue 2/35:40 amTYS - PDX

2 stops10h 06mDelta

Deal found 12/28

$368

One-way flights from Portland to Knoxville
Search for one-way flight options from Portland to Knoxville. Find affordable one-way fares based on user searches. Data last updated December 30, 2025.

Sat 1/1710:15 pmPDX - TYS

1 stop8h 30mAmerican Airlines

Deal found 12/29

$151

Wed 3/259:53 amPDX - TYS

1 stop27h 41mMultiple Airlines

Deal found 12/28

$153

Sat 1/175:00 amPDX - TYS

2 stops12h 52mUnited Airlines

Deal found 12/29

$156

Wed 1/286:00 amPDX - TYS

1 stop8h 42mAmerican Airlines

Deal found 12/28

$180

Wed 3/256:30 amPDX - TYS

2 stops10h 35mSouthwest

Deal found 12/29

$224

Fri 1/1610:47 amPDX - TYS

1 stop7h 05mUnited Airlines

Deal found 12/30

$279

Find flight deals from Portland to Knoxville

Most accurate provider	eDreams 3 stars
Most trusted provider	eDreams 3 stars
Round-trip from	$338 (Kiwi.com)
One-way from	$151 (American Airlines)
Popular in	March
Cheapest in	February
Average price	$559

Provider with most accurate pricing for Portland-Knoxville McGhee Tyson flight deals.

Search Deals

Provider most trusted by Cheapflights users for Portland-Knoxville McGhee Tyson flights.

Search Deals

From Portland to Knoxville McGhee Tyson

Search Deals

One-way flight from Portland to Knoxville McGhee Tyson

Search Deals

Highest demand for flights based on searches. 3% potential increase in price ($13 potential increase over avg. RT price).

Search Deals

Cheapest flight prices on average. 2% potential price decrease ($13 potential savings vs. average RT price).

Search Deals

Average for round-trip flights in December 2025

Search Deals

Cheapflights Fare Finder

Use the filters below to find and compare flights from Portland to Knoxville that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

PortlandKnoxville

PDX - TYS

PDXTYS

Portland

Tue 1/27

11:59 am-11:45 pm

1 stop8h 46m

Knoxville McGhee Tyson

Wed 2/4

6:30 am-12:46 pm

1 stop9h 16m

$359

PortlandKnoxville

PDX - TYS

PDXTYS

Portland

Sat 1/31

11:44 am-11:45 pm

1 stop9h 01m

Knoxville McGhee Tyson

Wed 2/4

6:30 am-12:46 pm

1 stop9h 16m

$363

PortlandKnoxville

PDX - TYS

PDXTYS

Portland

Tue 1/27

9:45 pm-9:21 am

1 stop8h 36m

Knoxville McGhee Tyson

Tue 2/3

10:07 am-5:35 pm

2 stops10h 28m

$364

PortlandKnoxville

PDX - TYS

PDXTYS

Portland

Thu 1/29

1:53 pm-11:09 pm

1 stop6h 16m

Knoxville McGhee Tyson

Sat 2/7

6:30 am-12:46 pm

1 stop9h 16m

$376

PortlandKnoxville

PDX - TYS

PDXTYS

Portland

Mon 1/26

7:37 pm-9:21 am

2 stops10h 44m

Knoxville McGhee Tyson

Tue 2/3

5:40 am-10:47 am

1 stop8h 07m

$377

PortlandKnoxville

PDX - TYS

PDXTYS

Portland

Mon 1/26

9:45 pm-9:21 am

1 stop8h 36m

Knoxville McGhee Tyson

Wed 2/4

7:30 am-5:35 pm

2 stops13h 05m

$377

PortlandKnoxville

PDX - TYS

PDXTYS

Portland

Tue 1/27

5:00 pm-9:21 am

2 stops13h 21m

Knoxville McGhee Tyson

Mon 2/2

11:58 am-8:32 pm

2 stops11h 34m

$382

PortlandKnoxville

PDX - TYS

PDXTYS

Portland

Wed 1/28

6:00 am-8:47 pm

2 stops11h 47m

Knoxville McGhee Tyson

Thu 2/5

7:30 am-5:35 pm

2 stops13h 05m

$382

PortlandKnoxville

PDX - TYS

PDXTYS

Portland

Mon 1/26

1:53 pm-11:09 pm

1 stop6h 16m

Knoxville McGhee Tyson

Thu 2/5

5:40 am-10:47 am

1 stop8h 07m

$385

PortlandKnoxville

PDX - TYS

PDXTYS

Portland

Mon 1/26

9:45 pm-9:21 am

1 stop8h 36m

Knoxville McGhee Tyson

Mon 2/2

11:58 am-8:32 pm

2 stops11h 34m

$390

Flights are sorted by cheapest round-trip flights first.

Deals found on 12/29

Showing 1-10 of 18 results

Compare providers for flights from Portland to Knoxville

Use the table below to compare price accuracy, trust ratings, and cancellation policies for each provider offering flight deals from Portland to Knoxville in December.

Provider	Price Accuracy	Trust Score*
Expedia	Price Accuracy2 stars	Trust Score*3 stars
FlightHub	Price Accuracy3 stars	Trust Score*1 star
eDreams	Price Accuracy3 stars	Trust Score*3 stars

*The Trust Score is based on feedback from users after their booking experience. It measures overall satisfaction, helping us identify issues like hidden fees, problems during the ticketing process, and the quality of customer service. This score is our best indicator of the provider's quality and reliability.

Most accurate provider: When it comes to deals on Portland-Knoxville flights, users find the pricing of eDreams to be most consistent on Cheapflights vs. eDreams Users can find the same prices on Portland-Knoxville flight deals on Cheapflights vs. eDreams >95% of the time. Price accuracy is based on data collected from Portland-Knoxville flight searches over the past month and is updated monthly.
Most trusted provider: When it comes to deals on Portland-Knoxville flights, Cheapflights users trust eDreams the most. eDreams has received a user feedback score of 3 out of 3 stars (3 being the best), meaning they have been trusted the most by Cheapflights users looking for Portland-Knoxville flight deals. Provider user feedback score is based on Cheapflights searches over the past month and is updated monthly.

Best time to book a flight from Portland to Knoxville

Have a flexible travel schedule? Discover the best time to fly to Knoxville from Portland with our price prediction graph.

Estimated round-trip price

Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Portland to Knoxville

How far ahead should I book a flight from Portland to Knoxville?

The best time to book flights from Portland to Knoxville is 23 days before your desired departure date. The cost of your flight will likely increase significantly if you book two weeks in advance of your flight.

What is the cheapest month to book a flight from Portland to Knoxville?

Currently, July is the cheapest month in which you can book a flight from Portland to Knoxville (average of $128). Flying from Portland to Knoxville in January is currently the most expensive (average of $308). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

Reviews of airlines servicing Knoxville

Read through reviews of airlines operating flights from Portland to Knoxville, such as Delta, United Airlines, and American Airlines. Reviews also offer insight into each airline's entertainment options, comfort, food, crew/service, and boarding process.

Delta

7.9

Good

8,013 reviews

Reviews

1 / 20

6.0

Good

Jim,Nov 2025

AVL - ATL

The exit row seats without a seat in front are great for leg room but don’t have a fold out entertainment console so you’re forced to use the screen several feet in front of you (there is, at least, a remote). Best to bring a tablet loaded with entertainment or a book.

Delta

7.9

Good

8,013 reviews

Delta

7.9

Good

8,013 reviews

Reviews

1 / 20

6.0

Good

Jim,Nov 2025

AVL - ATL

United Airlines

7.4

Good

9,124 reviews

Delta

7.9

Good

8,013 reviews

Reviews

1 / 20

6.0

Good

Jim,Nov 2025

AVL - ATL

American Airlines

7.2

Good

11,074 reviews

Delta

7.9

Good

8,013 reviews

Reviews

1 / 20

6.0

Good

Jim,Nov 2025

AVL - ATL

Frontier

5.7

Fair

3,068 reviews

Delta

7.9

Good

8,013 reviews

Reviews

1 / 20

6.0

Good

Jim,Nov 2025

AVL - ATL

Related info for your journey

How long is the flight from Portland to Knoxville?
For as low as $359, Delta can have you in Knoxville from Portland in 8h 46m. There are 2107 mi between Portland and Knoxville.
What are the cheapest airlines flying from Portland to Knoxville round-trip?
Cheapflights users have booked flights from Portland to Knoxville round-trip from $240. Other airlines that can offer you cheap pricing are United Airlines, from $248, and Delta, from $278. Frontier is 46% cheaper than the average price of flights available within the next 90 days to this destination.
What are the cheapest airlines to fly from Portland to Knoxville one-way?
The cheapest airline one-way is Frontier, with whom users have recently found tickets for as low as $107. However, be on the lookout for offers from American Airlines and Delta, as they are both options that can get you from Portland to Knoxville for a low price.
Can I find deals for flights from Portland to Knoxville that include hotel bookings?
Yes. In addition to deals on Portland to Knoxville flights, Cheapflights offers vacation packages that include both flights and hotel.
How can I find direct flights from Portland to Knoxville?
After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Portland to Knoxville.
Can I find deals for business class flights from Portland to Knoxville?
Yes. Cheapflights offers flight deals from Portland to Knoxville by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.
What is the cheapest month to book a flight from Portland to Knoxville?
Currently, July is the cheapest month in which you can book a flight from Portland to Knoxville (average of $128). Flying from Portland to Knoxville in January is currently the most expensive (average of $308). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

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Other flights to Knoxville

Top 4 airlines flying from Portland to Knoxville

Airline	Cheapest	Average	Flexibility	On-time
Frontier	Cheapest$240	Average$290	FlexibilityNo cancel fee	On-time62%
United Airlines	Cheapest$278	Average$489	FlexibilityNo cancel fee	On-time69%
Delta	Cheapest$278	Average$454	FlexibilityNo cancel fee	On-timeN/A
American Airlines	Cheapest$293	Average$462	FlexibilityNo cancel fee	On-time71%

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$151+ Cheap flights from Portland to Knoxville (PDX - TYS)

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 1/17. Fares are subject to change and may not be available on all flights or dates of travel.

Find cheap flights from Portland to Knoxville with Cheapflights

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Cheap flight deals from Portland to Knoxville

Cheapest flights from Portland to KnoxvilleExplore the most affordable flight options available from Portland to Knoxville. Find the lowest fares from popular airlines and budget airlines, with prices last updated on December 30, 2025.

Explore the most affordable flight options available from Portland to Knoxville. Find the lowest fares from popular airlines and budget airlines, with prices last updated on December 30, 2025.

Find flight deals from Portland to Knoxville

Most accurate provider

Most trusted provider

Round-trip from

One-way from

Popular in

Cheapest in

Average price

Cheapflights Fare Finder

Use the filters below to find and compare flights from Portland to Knoxville that are best for you.

Compare providers for flights from Portland to Knoxville

Provider information is updated monthly. Please note that these providers often have deals for this flight, but the availability may vary on a day-by-day basis on Cheapflights.

Use the table below to compare price accuracy, trust ratings, and cancellation policies for each provider offering flight deals from Portland to Knoxville in December.

Best time to book a flight from Portland to Knoxville

Have a flexible travel schedule? Discover the best time to fly to Knoxville from Portland with our price prediction graph.

Cheapflights Insights

Everything you need to know about your flight from Portland to Knoxville

How far ahead should I book a flight from Portland to Knoxville?

What is the cheapest month to book a flight from Portland to Knoxville?

Reviews of airlines servicing Knoxville

Read through reviews of airlines operating flights from Portland to Knoxville, such as Delta, United Airlines, and American Airlines. Reviews also offer insight into each airline's entertainment options, comfort, food, crew/service, and boarding process.

Related info for your journey

Find useful and relevant information for your journey from Portland to Knoxville. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

How long is the flight from Portland to Knoxville?

What are the cheapest airlines flying from Portland to Knoxville round-trip?

What are the cheapest airlines to fly from Portland to Knoxville one-way?

Can I find deals for flights from Portland to Knoxville that include hotel bookings?

How can I find direct flights from Portland to Knoxville?

Can I find deals for business class flights from Portland to Knoxville?

What is the cheapest month to book a flight from Portland to Knoxville?

Traveling to a place near Knoxville?

Browse thousands of different options on Cheapflights for your next trip

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Alternative routes for Portland to Knoxville

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Top 4 airlines flying from Portland to Knoxville

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Cheapest flights from Portland to Knoxville
Explore the most affordable flight options available from Portland to Knoxville. Find the lowest fares from popular airlines and budget airlines, with prices last updated on December 30, 2025.