How long is the flight from Portland to Knoxville?

For as low as $334, United Airlines can have you in Knoxville from Portland in 7h 05m. There are 2107 mi between Portland and Knoxville. This flight may include one or multiple stops.

What are the cheapest airlines flying from Portland to Knoxville round-trip?

Cheapflights users have booked flights from Portland to Knoxville round-trip from $240. Other airlines that can offer you cheap pricing are United Airlines, from $248, and Delta, from $279. Frontier is 46% cheaper than the average price of flights available within the next 90 days to this destination.

What are the cheapest airlines to fly from Portland to Knoxville one-way?

The cheapest airline one-way is Frontier, with whom users have recently found tickets for as low as $107. However, be on the lookout for offers from American Airlines and Delta, as they are both options that can get you from Portland to Knoxville for a low price.

In terms of precipitation, rainfall in Knoxville ranges from 2.7 - 4.8 inches per month. March is typically the wettest month, when rainfall can reach 4.8 in. October is typically the driest time to visit Knoxville when rainfall is around 2.7 in.

If weather is an important factor for your trip to Knoxville, use this chart to help with planning. For those seeking warmer temperatures, July is the ideal time of year to visit, when temperatures reach an average of 78.8 F. Travelers looking to avoid the cold should look outside of January, when temperatures are typically at their lowest (around 39.2 F).

What are the most popular airlines that fly from Portland to Knoxville?

Consider American Airlines, Delta or United Airlines when booking your flight. These represent the most popular airlines when flying from Portland to Knoxville.

Most accurate provider : When it comes to deals on Portland-Knoxville flights, users find the pricing of eDreams to be most consistent on Cheapflights vs. eDreams Users can find the same prices on Portland-Knoxville flight deals on Cheapflights vs. eDreams >95% of the time. Price accuracy is based on data collected from Portland-Knoxville flight searches over the past month and is updated monthly.

Most trusted provider : When it comes to deals on Portland-Knoxville flights, Cheapflights users trust eDreams the most. eDreams has received a user feedback score of 3 out of 3 stars (3 being the best), meaning they have been trusted the most by Cheapflights users looking for Portland-Knoxville flight deals. Provider user feedback score is based on Cheapflights searches over the past month and is updated monthly.

Can I find deals for flights from Portland to Knoxville that include hotel bookings?

Yes. In addition to deals on Portland to Knoxville flights, Cheapflights offers vacation packages that include both flights and hotel.

How can I find direct flights from Portland to Knoxville?

After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Portland to Knoxville.

Can I find deals for business class flights from Portland to Knoxville?

Yes. Cheapflights offers flight deals from Portland to Knoxville by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

$219+ Flights from Portland to Knoxville

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Cheapflights Tip: The best prices from Portland to Knoxville McGhee Tyson are usually found in February or August, booked 23 days in advance, depart on a Tuesday or Wednesday and return on a Wednesday

Cheap flight deals from Portland to Knoxville

Cheapest flights from Portland to Knoxville
Explore the most affordable flight options available from Portland to Knoxville. Find the lowest fares from popular airlines and budget airlines, with prices last updated on December 18, 2025.

Thu 12/257:00 amPDX - TYS

1 stop9h 50mUnited Airlines

Thu 1/18:40 amTYS - PDX

1 stop7h 55mUnited Airlines

Deal found 12/16

$536

Sun 12/2112:49 amPDX - TYS

1 stop7h 39mAmerican Airlines

Tue 1/64:41 pmTYS - PDX

1 stop8h 30mAmerican Airlines

Deal found 12/16

$583

Mon 12/225:30 amPDX - TYS

2 stops12h 02mDelta

Tue 1/61:00 pmTYS - PDX

2 stops12h 54mDelta

Deal found 12/16

$642

Thu 12/252:29 pmPDX - TYS

1 stop23h 33mMultiple Airlines

Sat 1/312:21 pmTYS - PDX

2 stops28h 03mMultiple Airlines

Deal found 12/16

$668

Tue 12/236:27 pmPDX - TYS

2 stops13h 29mUnited Airlines

Tue 1/611:10 amTYS - PDX

2 stops25h 35mUnited Airlines

Deal found 12/17

$711

Wed 12/312:45 pmPDX - TYS

2 stops23h 15mUnited Airlines

Sun 1/42:00 pmTYS - PDX

1 stop9h 48mUnited Airlines

Deal found 12/15

$726

Best flights from Portland to Knoxville
Discover carefully curated flight deals from Portland to Knoxville that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated December 18, 2025.

Wed 1/1410:47 amPDX - TYS

1 stop7h 05mUnited Airlines

Sun 1/186:45 amTYS - PDX

1 stop8h 12mUnited Airlines

Deal found 12/16

$334

Tue 1/1310:00 amPDX - TYS

2 stops10h 09mDelta

Tue 1/207:30 amTYS - PDX

2 stops14h 20mDelta

Deal found 12/15

$344

Thu 1/1512:35 pmPDX - TYS

1 stop7h 12mAmerican Airlines

Sun 1/184:41 pmTYS - PDX

1 stop9h 51mAmerican Airlines

Deal found 12/16

$367

Tue 1/135:00 amPDX - TYS

1 stop7h 14mUnited Airlines

Tue 1/209:30 amTYS - PDX

2 stops12h 26mUnited Airlines

Deal found 12/15

$339

Wed 1/217:00 amPDX - TYS

1 stop8h 05mUnited Airlines

Tue 1/274:55 pmTYS - PDX

1 stop8h 58mUnited Airlines

Deal found 12/16

$367

Sun 1/1111:59 pmPDX - TYS

1 stop8h 35mAmerican Airlines

Sat 1/173:00 pmTYS - PDX

2 stops10h 11mAmerican Airlines

Deal found 12/16

$404

Tue 2/310:15 pmPDX - TYS

1 stop8h 30mAmerican Airlines

Fri 2/612:19 pmTYS - PDX

2 stops12h 02mAmerican Airlines

Deal found 12/17

$407

Thu 1/1511:59 pmPDX - TYS

1 stop7h 33mUnited Airlines

Sun 1/186:45 amTYS - PDX

2 stops11h 03mUnited Airlines

Deal found 12/16

$374

Tue 2/35:00 amPDX - TYS

2 stops11h 27mUnited Airlines

Fri 2/61:59 pmTYS - PDX

1 stop7h 57mUnited Airlines

Deal found 12/16

$407

Last-minute flights from Portland to Knoxville
Discover last-minute flight deals from Portland to Knoxville. Data last updated December 18, 2025 and is based on user searches.

Sun 1/116:00 amPDX - TYS

1 stop6h 46mAmerican Airlines

Sat 1/176:00 amTYS - PDX

1 stop8h 45mAmerican Airlines

Deal found 12/16

$399

Tue 1/135:00 amPDX - TYS

1 stop7h 14mUnited Airlines

Tue 1/209:30 amTYS - PDX

2 stops12h 26mUnited Airlines

Deal found 12/15

$339

Tue 1/1310:00 amPDX - TYS

2 stops10h 09mDelta

Tue 1/207:30 amTYS - PDX

2 stops14h 20mDelta

Deal found 12/15

$344

Wed 1/1410:47 amPDX - TYS

1 stop7h 05mUnited Airlines

Sun 1/186:45 amTYS - PDX

1 stop8h 12mUnited Airlines

Deal found 12/16

$334

Thu 1/1512:35 pmPDX - TYS

1 stop7h 12mAmerican Airlines

Sun 1/184:41 pmTYS - PDX

1 stop9h 51mAmerican Airlines

Deal found 12/16

$367

Thu 1/1511:59 pmPDX - TYS

1 stop7h 33mUnited Airlines

Sun 1/186:45 amTYS - PDX

2 stops11h 03mUnited Airlines

Deal found 12/16

$374

Thu 1/1512:35 pmPDX - TYS

1 stop7h 12mAmerican Airlines

Wed 1/216:00 amTYS - PDX

1 stop8h 45mAmerican Airlines

Deal found 12/15

$388

Wed 1/2112:59 pmPDX - TYS

1 stop7h 45mUnited Airlines

Tue 1/279:30 amTYS - PDX

2 stops11h 40mUnited Airlines

Deal found 12/16

$372

One-way flights from Portland to Knoxville
Search for one-way flight options from Portland to Knoxville. Find affordable one-way fares based on user searches. Data last updated December 18, 2025.

Wed 5/1312:04 pmPDX - TYS

1 stop8h 43mAmerican Airlines

Deal found 12/16

$219

Sun 5/179:45 pmPDX - TYS

1 stop8h 26mDelta

Deal found 12/17

$240

Wed 5/135:30 amPDX - TYS

2 stops13h 53mUnited Airlines

Deal found 12/17

$274

Sat 1/35:33 amPDX - TYS

1 stop8h 57mAmerican Airlines

Deal found 12/17

$279

Fri 12/2611:55 pmPDX - TYS

1 stop7h 22mUnited Airlines

Deal found 12/16

$327

Sun 1/46:27 pmPDX - TYS

2 stops13h 29mUnited Airlines

Deal found 12/17

$334

Sat 1/31:51 pmPDX - TYS

2 stops17h 33mAlaska Airlines

Deal found 12/17

$359

Sun 6/77:45 pmPDX - TYS

2 stops11h 27mAlaska Airlines

Deal found 12/17

$364

Sun 5/175:30 amPDX - TYS

3 stops13h 53mUnited Airlines

Deal found 12/16

$387

Find flight deals from Portland to Knoxville

Most accurate provider	eDreams 3 stars
Most trusted provider	eDreams 3 stars
Round-trip from	$334 (United Airlines)
One-way from	$219 (American Airlines)
Popular in	March
Cheapest in	February
Average price	$559

Provider with most accurate pricing for Portland-Knoxville McGhee Tyson flight deals.

Search Deals

Provider most trusted by Cheapflights users for Portland-Knoxville McGhee Tyson flights.

Search Deals

From Portland to Knoxville McGhee Tyson

Search Deals

One-way flight from Portland to Knoxville McGhee Tyson

Search Deals

Highest demand for flights based on searches. 3% potential increase in price ($13 potential increase over avg. RT price).

Search Deals

Cheapest flight prices on average. 2% potential price decrease ($13 potential savings vs. average RT price).

Search Deals

Average for round-trip flights in December 2025

Search Deals

Cheapflights Fare Finder

Use the filters below to find and compare flights from Portland to Knoxville that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

PortlandKnoxville

PDX - TYS

PDXTYS

Portland

Wed 1/14

10:47 am-8:52 pm

1 stop7h 05m

Knoxville McGhee Tyson

Sun 1/18

6:45 am-11:57 am

1 stop8h 12m

$334

PortlandKnoxville

PDX - TYS

PDXTYS

Portland

Tue 1/13

5:00 am-3:14 pm

1 stop7h 14m

Knoxville McGhee Tyson

Tue 1/20

9:30 am-6:56 pm

2 stops12h 26m

$339

PortlandKnoxville

PDX - TYS

PDXTYS

Portland

Tue 1/13

10:00 am-11:09 pm

2 stops10h 09m

Knoxville McGhee Tyson

Tue 1/20

7:30 am-6:50 pm

2 stops14h 20m

$344

PortlandKnoxville

PDX - TYS

PDXTYS

Portland

Thu 1/15

12:35 pm-10:47 pm

1 stop7h 12m

Knoxville McGhee Tyson

Sun 1/18

4:41 pm-11:32 pm

1 stop9h 51m

$367

PortlandKnoxville

PDX - TYS

PDXTYS

Portland

Wed 1/21

7:00 am-6:05 pm

1 stop8h 05m

Knoxville McGhee Tyson

Tue 1/27

4:55 pm-10:53 pm

1 stop8h 58m

$367

PortlandKnoxville

PDX - TYS

PDXTYS

Portland

Thu 1/15

11:59 pm-10:32 am

1 stop7h 33m

Knoxville McGhee Tyson

Sun 1/18

6:45 am-2:48 pm

2 stops11h 03m

$374

PortlandKnoxville

PDX - TYS

PDXTYS

Portland

Sun 1/11

11:59 pm-11:34 am

1 stop8h 35m

Knoxville McGhee Tyson

Sat 1/17

3:00 pm-10:11 pm

2 stops10h 11m

$404

PortlandKnoxville

PDX - TYS

PDXTYS

Portland

Tue 2/3

10:15 pm-9:45 am

1 stop8h 30m

Knoxville McGhee Tyson

Fri 2/6

12:19 pm-9:21 pm

2 stops12h 02m

$407

PortlandKnoxville

PDX - TYS

PDXTYS

Portland

Tue 2/3

5:00 am-7:27 pm

2 stops11h 27m

Knoxville McGhee Tyson

Fri 2/6

1:59 pm-6:56 pm

1 stop7h 57m

$407

PortlandKnoxville

PDX - TYS

PDXTYS

Portland

Wed 5/13

12:04 pm-11:47 pm

1 stop8h 43m

$219

Flights are sorted by cheapest round-trip flights first.

Deals found on 12/16

Showing 1-10 of 16 results

Compare providers for flights from Portland to Knoxville

Use the table below to compare price accuracy, trust ratings, and cancellation policies for each provider offering flight deals from Portland to Knoxville in December.

Provider	Price Accuracy	Trust Score*
Expedia	Price Accuracy2 stars	Trust Score*3 stars
FlightHub	Price Accuracy3 stars	Trust Score*1 star
eDreams	Price Accuracy3 stars	Trust Score*3 stars

*The Trust Score is based on feedback from users after their booking experience. It measures overall satisfaction, helping us identify issues like hidden fees, problems during the ticketing process, and the quality of customer service. This score is our best indicator of the provider's quality and reliability.

Most accurate provider: When it comes to deals on Portland-Knoxville flights, users find the pricing of eDreams to be most consistent on Cheapflights vs. eDreams Users can find the same prices on Portland-Knoxville flight deals on Cheapflights vs. eDreams >95% of the time. Price accuracy is based on data collected from Portland-Knoxville flight searches over the past month and is updated monthly.
Most trusted provider: When it comes to deals on Portland-Knoxville flights, Cheapflights users trust eDreams the most. eDreams has received a user feedback score of 3 out of 3 stars (3 being the best), meaning they have been trusted the most by Cheapflights users looking for Portland-Knoxville flight deals. Provider user feedback score is based on Cheapflights searches over the past month and is updated monthly.

Best time to book a flight from Portland to Knoxville

Have a flexible travel schedule? Discover the best time to fly to Knoxville from Portland with our price prediction graph.

Estimated round-trip price

Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Portland to Knoxville

How far ahead should I book a flight from Portland to Knoxville?

The best time to book flights from Portland to Knoxville is 23 days before your desired departure date. The cost of your flight will likely increase significantly if you book two weeks in advance of your flight.

What is the cheapest month to book a flight from Portland to Knoxville?

Currently, July is the cheapest month in which you can book a flight from Portland to Knoxville (average of $128). Flying from Portland to Knoxville in January is currently the most expensive (average of $308). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

What is the cheapest time of day to fly from PDX to TYS?

When flying from Portland to Knoxville, the time of day you fly usually plays a role in the price. Save by searching for a flight in the afternoon, which can drop the price by up to 27% versus a flight in the evening.

Reviews of airlines servicing Knoxville

Read through reviews of airlines operating flights from Portland to Knoxville, such as Delta, United Airlines, and American Airlines. Reviews also offer insight into each airline's entertainment options, comfort, food, crew/service, and boarding process.

Delta

7.9

Good

8,005 reviews

Reviews

1 / 20

6.0

Good

Jim,Nov 2025

AVL - ATL

The exit row seats without a seat in front are great for leg room but don’t have a fold out entertainment console so you’re forced to use the screen several feet in front of you (there is, at least, a remote). Best to bring a tablet loaded with entertainment or a book.

Delta

7.9

Good

8,005 reviews

Delta

7.9

Good

8,005 reviews

Reviews

1 / 20

6.0

Good

Jim,Nov 2025

AVL - ATL

United Airlines

7.4

Good

9,092 reviews

Delta

7.9

Good

8,005 reviews

Reviews

1 / 20

6.0

Good

Jim,Nov 2025

AVL - ATL

American Airlines

7.2

Good

11,055 reviews

Delta

7.9

Good

8,005 reviews

Reviews

1 / 20

6.0

Good

Jim,Nov 2025

AVL - ATL

Frontier

5.8

Fair

3,081 reviews

Delta

7.9

Good

8,005 reviews

Reviews

1 / 20

6.0

Good

Jim,Nov 2025

AVL - ATL

Related info for your journey

How long is the flight from Portland to Knoxville?
For as low as $334, United Airlines can have you in Knoxville from Portland in 7h 05m. There are 2107 mi between Portland and Knoxville. This flight may include one or multiple stops.
What are the cheapest airlines flying from Portland to Knoxville round-trip?
Cheapflights users have booked flights from Portland to Knoxville round-trip from $240. Other airlines that can offer you cheap pricing are United Airlines, from $248, and Delta, from $279. Frontier is 46% cheaper than the average price of flights available within the next 90 days to this destination.
What are the cheapest airlines to fly from Portland to Knoxville one-way?
The cheapest airline one-way is Frontier, with whom users have recently found tickets for as low as $107. However, be on the lookout for offers from American Airlines and Delta, as they are both options that can get you from Portland to Knoxville for a low price.
Can I find deals for flights from Portland to Knoxville that include hotel bookings?
Yes. In addition to deals on Portland to Knoxville flights, Cheapflights offers vacation packages that include both flights and hotel.
How can I find direct flights from Portland to Knoxville?
After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Portland to Knoxville.
Can I find deals for business class flights from Portland to Knoxville?
Yes. Cheapflights offers flight deals from Portland to Knoxville by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.
What is the cheapest month to book a flight from Portland to Knoxville?
Currently, July is the cheapest month in which you can book a flight from Portland to Knoxville (average of $128). Flying from Portland to Knoxville in January is currently the most expensive (average of $308). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

Cherokee

Crossville

Corbin

Morristown

Bryson City

Alcoa

Oak Ridge

Murphy

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Top 4 airlines flying from Portland to Knoxville

Airline	Cheapest	Average	Flexibility	On-time
Frontier	Cheapest$240	Average$290	FlexibilityNo cancel fee	On-time62%
United Airlines	Cheapest$278	Average$489	FlexibilityNo cancel fee	On-time69%
Delta	Cheapest$279	Average$451	FlexibilityNo cancel fee	On-timeN/A
American Airlines	Cheapest$293	Average$458	FlexibilityNo cancel fee	On-time71%

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$219+ Cheap flights from Portland to Knoxville (PDX - TYS)

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 5/13. Fares are subject to change and may not be available on all flights or dates of travel.

Find cheap flights from Portland to Knoxville with Cheapflights

1. Tell us where you want to go

2. Select your favorite providers

3. Compare prices and book

Cheapflights Tip: The best prices from Portland to Knoxville McGhee Tyson are usually found in February or August, booked 23 days in advance, depart on a Tuesday or Wednesday and return on a Wednesday

Cheap flight deals from Portland to Knoxville

Cheapest flights from Portland to KnoxvilleExplore the most affordable flight options available from Portland to Knoxville. Find the lowest fares from popular airlines and budget airlines, with prices last updated on December 18, 2025.

Explore the most affordable flight options available from Portland to Knoxville. Find the lowest fares from popular airlines and budget airlines, with prices last updated on December 18, 2025.

Find flight deals from Portland to Knoxville

Most accurate provider

Most trusted provider

Round-trip from

One-way from

Popular in

Cheapest in

Average price

Cheapflights Fare Finder

Use the filters below to find and compare flights from Portland to Knoxville that are best for you.

Compare providers for flights from Portland to Knoxville

Provider information is updated monthly. Please note that these providers often have deals for this flight, but the availability may vary on a day-by-day basis on Cheapflights.

Use the table below to compare price accuracy, trust ratings, and cancellation policies for each provider offering flight deals from Portland to Knoxville in December.

Best time to book a flight from Portland to Knoxville

Have a flexible travel schedule? Discover the best time to fly to Knoxville from Portland with our price prediction graph.

Cheapflights Insights

Everything you need to know about your flight from Portland to Knoxville

How far ahead should I book a flight from Portland to Knoxville?

What is the cheapest month to book a flight from Portland to Knoxville?

What is the cheapest time of day to fly from PDX to TYS?

Reviews of airlines servicing Knoxville

Read through reviews of airlines operating flights from Portland to Knoxville, such as Delta, United Airlines, and American Airlines. Reviews also offer insight into each airline's entertainment options, comfort, food, crew/service, and boarding process.

Related info for your journey

Find useful and relevant information for your journey from Portland to Knoxville. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

How long is the flight from Portland to Knoxville?

What are the cheapest airlines flying from Portland to Knoxville round-trip?

What are the cheapest airlines to fly from Portland to Knoxville one-way?

Can I find deals for flights from Portland to Knoxville that include hotel bookings?

How can I find direct flights from Portland to Knoxville?

Can I find deals for business class flights from Portland to Knoxville?

What is the cheapest month to book a flight from Portland to Knoxville?

Traveling to a place near Knoxville?

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Alternative routes for Portland to Knoxville

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Top 4 airlines flying from Portland to Knoxville

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Cheapest flights from Portland to Knoxville
Explore the most affordable flight options available from Portland to Knoxville. Find the lowest fares from popular airlines and budget airlines, with prices last updated on December 18, 2025.