$193+ Cheap flights from Portland to Knoxville (PDX - TYS)
This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 9/18. Fares are subject to change and may not be available on all flights or dates of travel.
PDX — TYS
Sep 16 — Sep 231
Round-trip
1 adult, Economy
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Find cheap flights from Portland to Knoxville with Cheapflights
1. Tell us where you want to go
Enter your travel information like dates, passengers, trip type (one-way or round trip), and preferred cabin class then click “Find deals”2. Select your favorite providers
We find the providers serving your travel needs. Choose up to four travel providers to compare side-by-side for flights, hotels, or car rentals.3. Compare prices and book
Review each provider’s pricing and select the best option for you! Book through your favorite provider’s website for a seamless experience.Cheap flight deals from Portland to Knoxville
Cheapest
Best
Last-minute
One-way
Cheapest flights from Portland to KnoxvilleExplore the most affordable flight options available from Portland to Knoxville. Find the lowest fares from popular airlines and budget airlines, with prices last updated on August 17, 2026.
Explore the most affordable flight options available from Portland to Knoxville. Find the lowest fares from popular airlines and budget airlines, with prices last updated on August 17, 2026.
This American Airlines deal was found by Cheapflights users on 8/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 9/129:44 pm -
1 stop7h 46m
Tue 9/226:00 am -
1 stop10h 17m
Deal found 8/13![American Airlines logo]()
$299
This American Airlines deal was found by Cheapflights users on 8/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 9/55:59 am -
1 stop9h 22m
Fri 9/114:48 pm -
1 stop10h 19m
Deal found 8/13![American Airlines logo]()
$331
This American Airlines deal was found by Cheapflights users on 8/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 9/811:09 pm -
1 stop8h 41m
Tue 9/155:35 pm -
1 stop8h 48m
Deal found 8/13![American Airlines logo]()
$334
This Delta deal was found by Cheapflights users on 8/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 9/1910:57 pm -
1 stop9h 21m
Fri 9/255:20 pm -
1 stop7h 27m
Deal found 8/12![Delta logo]()
$341
This United Airlines deal was found by Cheapflights users on 8/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 9/128:40 am -
2 stops10h 05m
Sat 9/196:00 pm -
1 stop7h 52m
Deal found 8/16![United Airlines logo]()
$342
This United Airlines deal was found by Cheapflights users on 8/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 11/611:30 pm -
1 stop7h 37m
Sat 11/146:45 am -
2 stops9h 40m
Deal found 8/12![United Airlines logo]()
$346
This American Airlines deal was found by Cheapflights users on 8/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 9/2911:08 pm -
2 stops9h 33m
Wed 9/304:48 pm -
1 stop10h 19m
Deal found 8/13![American Airlines logo]()
$347
This American Airlines deal was found by Cheapflights users on 8/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 9/196:01 am -
1 stop7h 10m
Fri 9/255:35 pm -
1 stop8h 48m
Deal found 8/14![American Airlines logo]()
$361
This United Airlines deal was found by Cheapflights users on 8/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 9/197:02 am -
1 stop6h 56m
Sat 9/266:00 am -
2 stops10h 15m
Deal found 8/15![United Airlines logo]()
$363
This American Airlines deal was found by Cheapflights users on 8/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 12/161:22 pm -
1 stop7h 25m
Wed 12/302:44 pm -
1 stop10h 23m
Deal found 8/15![American Airlines logo]()
$367
Best flights from Portland to KnoxvilleDiscover carefully curated flight deals from Portland to Knoxville that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated August 17, 2026.
Discover carefully curated flight deals from Portland to Knoxville that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated August 17, 2026.
This United Airlines deal was found by Cheapflights users on 8/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 9/1910:35 am -
1 stop9h 14m
Sat 9/266:00 am -
1 stop8h 33m
Deal found 8/16![United Airlines logo]()
$337
This Southwest deal was found by Cheapflights users on 8/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 12/115:10 am -
2 stops10h 35m
Mon 12/147:05 am -
2 stops9h 05m
Deal found 8/16![Southwest logo]()
$392
This United Airlines deal was found by Cheapflights users on 8/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 9/128:40 am -
2 stops10h 05m
Sat 9/196:00 pm -
1 stop7h 52m
Deal found 8/16![United Airlines logo]()
$342
This Southwest deal was found by Cheapflights users on 8/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 9/1211:30 pm -
2 stops9h 55m
Sat 9/196:50 am -
2 stops10h 10m
Deal found 8/15![Southwest logo]()
$392
This United Airlines deal was found by Cheapflights users on 8/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 2/610:59 pm -
1 stop8h 00m
Tue 2/92:00 pm -
1 stop8h 07m
Deal found 8/13![United Airlines logo]()
$409
This Southwest deal was found by Cheapflights users on 8/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 9/1911:30 pm -
2 stops9h 55m
Sat 9/266:50 am -
2 stops10h 10m
Deal found 8/16![Southwest logo]()
$452
This United Airlines deal was found by Cheapflights users on 8/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 9/127:27 pm -
2 stops11h 27m
Tue 9/226:00 am -
2 stops11h 46m
Deal found 8/13![United Airlines logo]()
$455
Last-minute flights from Portland to KnoxvilleDiscover last-minute flight deals from Portland to Knoxville. Data last updated August 17, 2026 and is based on user searches.
Discover last-minute flight deals from Portland to Knoxville. Data last updated August 17, 2026 and is based on user searches.
This American Airlines deal was found by Cheapflights users on 8/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 9/55:59 am -
1 stop9h 22m
Fri 9/114:48 pm -
1 stop10h 19m
Deal found 8/13![American Airlines logo]()
$331
This American Airlines deal was found by Cheapflights users on 8/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 9/811:09 pm -
1 stop8h 41m
Tue 9/155:35 pm -
1 stop8h 48m
Deal found 8/13![American Airlines logo]()
$334
This American Airlines deal was found by Cheapflights users on 8/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 9/129:44 pm -
1 stop7h 46m
Tue 9/226:00 am -
1 stop10h 17m
Deal found 8/13![American Airlines logo]()
$299
This United Airlines deal was found by Cheapflights users on 8/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 9/127:02 am -
2 stops10h 22m
Sat 9/196:00 pm -
1 stop7h 52m
Deal found 8/15![United Airlines logo]()
$342
This Southwest deal was found by Cheapflights users on 8/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 9/1411:30 pm -
2 stops9h 35m
Thu 9/245:45 pm -
2 stops9h 00m
Deal found 8/15![Southwest logo]()
$368
This Delta deal was found by Cheapflights users on 8/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 9/1910:57 pm -
1 stop9h 21m
Fri 9/255:20 pm -
1 stop7h 27m
Deal found 8/12![Delta logo]()
$341
This American Airlines deal was found by Cheapflights users on 8/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 9/196:01 am -
1 stop7h 10m
Fri 9/255:35 pm -
1 stop8h 48m
Deal found 8/14![American Airlines logo]()
$361
This United Airlines deal was found by Cheapflights users on 8/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 9/197:02 am -
1 stop6h 56m
Sat 9/266:00 am -
2 stops10h 15m
Deal found 8/15![United Airlines logo]()
$363
This Southwest deal was found by Cheapflights users on 8/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 9/2111:30 pm -
2 stops9h 35m
Wed 9/233:00 pm -
1 stop10h 15m
Deal found 8/15![Southwest logo]()
$369
This American Airlines deal was found by Cheapflights users on 8/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 9/2911:08 pm -
2 stops9h 33m
Wed 9/304:48 pm -
1 stop10h 19m
Deal found 8/13![American Airlines logo]()
$347
One-way flights from Portland to KnoxvilleSearch for one-way flight options from Portland to Knoxville. Find affordable one-way fares based on user searches. Data last updated August 17, 2026.
Search for one-way flight options from Portland to Knoxville. Find affordable one-way fares based on user searches. Data last updated August 17, 2026.
This American Airlines deal was found by Cheapflights users on 8/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 9/1811:08 pm -
1 stop8h 42m
Deal found 8/16![American Airlines logo]()
$193
This American Airlines deal was found by Cheapflights users on 8/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/151:12 pm -
1 stop7h 47m
Deal found 8/12![American Airlines logo]()
$207
This United Airlines deal was found by Cheapflights users on 8/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 9/37:02 am -
1 stop6h 56m
Deal found 8/13![United Airlines logo]()
$208
This Kiwi.com deal was found by Cheapflights users on 8/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 8/265:56 pm -
3 stops44h 41m
Deal found 8/12![Multiple Airlines logo]()
$213
This Kiwi.com deal was found by Cheapflights users on 8/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 9/2412:38 pm -
2 stops21h 03m
Deal found 8/16![Multiple Airlines logo]()
$215
This Kiwi.com deal was found by Cheapflights users on 8/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/1511:06 am -
2 stops21h 08m
Deal found 8/12![Multiple Airlines logo]()
$219
This Delta deal was found by Cheapflights users on 8/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 10/1811:00 pm -
1 stop8h 54m
Deal found 8/12![Delta logo]()
$234
This Kiwi.com deal was found by Cheapflights users on 8/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 9/312:20 pm -
2 stops31h 36m
Deal found 8/13![Multiple Airlines logo]()
$238
This Southwest deal was found by Cheapflights users on 8/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 10/2511:35 pm -
2 stops9h 40m
Deal found 8/14![Southwest logo]()
$239
This Kiwi.com deal was found by Cheapflights users on 8/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 9/1812:38 pm -
3 stops49h 10m
Deal found 8/16![Multiple Airlines logo]()
$244
This United Airlines deal was found by Cheapflights users on 8/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 9/2511:30 pm -
1 stop7h 15m
Deal found 8/14![United Airlines logo]()
$248
Find flight deals from Portland to Knoxville
Discover tips and strategies to find the most affordable flight options for your journey from Portland (PDX) to Knoxville (TYS). Learn about various techniques such as flexible date searches, comparing prices across and setting up price alerts. Use these methods to find the cheapest flights available for your travel needs. Data last updated August 17, 2026.
Most accurate provider | FlightHub 3 stars |
|---|---|
Most trusted provider | FlightHub 3 stars |
Round-trip from | $299 (American Airlines) |
One-way from | $193 (American Airlines) |
Popular in | May |
Cheapest in | January |
Average price | $480 |
Cheapflights Fare Finder
Customize your flight search to find flights from Portland to Knoxville that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated August 17, 2026.
Use the filters below to find and compare flights from Portland to Knoxville that are best for you.
Fly from
Fly to
Route
Depart
Return
Cheapest round-trip
PortlandKnoxville
PDX Portland - TYS Knoxville McGhee Tyson
PDXTYS
Portland
Sat 9/19
10:35 am-10:49 pm
1 stop9h 14m
Knoxville McGhee Tyson
Sat 9/26
6:00 am-11:33 am
1 stop8h 33m
$337
PortlandKnoxville
PDX Portland - TYS Knoxville McGhee Tyson
PDXTYS
Portland
Sat 9/12
8:40 am-9:45 pm
2 stops10h 05m
Knoxville McGhee Tyson
Sat 9/19
6:00 pm-10:52 pm
1 stop7h 52m
$342
PortlandKnoxville
PDX Portland - TYS Knoxville McGhee Tyson
PDXTYS
Portland
Fri 12/11
5:10 am-6:45 pm
2 stops10h 35m
Knoxville McGhee Tyson
Mon 12/14
7:05 am-1:10 pm
2 stops9h 05m
$392
PortlandKnoxville
PDX Portland - TYS Knoxville McGhee Tyson
PDXTYS
Portland
Sat 9/12
11:30 pm-12:25 pm
2 stops9h 55m
Knoxville McGhee Tyson
Sat 9/19
6:50 am-2:00 pm
2 stops10h 10m
$392
Quickest round-trip
PortlandKnoxville
PDX Portland - TYS Knoxville McGhee Tyson
PDXTYS
Portland
Sat 2/6
10:59 pm-9:59 am
1 stop8h 00m
Knoxville McGhee Tyson
Tue 2/9
2:00 pm-7:07 pm
1 stop8h 07m
$409
PortlandKnoxville
PDX Portland - TYS Knoxville McGhee Tyson
PDXTYS
Portland
Sat 9/19
11:30 pm-12:25 pm
2 stops9h 55m
Knoxville McGhee Tyson
Sat 9/26
6:50 am-2:00 pm
2 stops10h 10m
$452
PortlandKnoxville
PDX Portland - TYS Knoxville McGhee Tyson
PDXTYS
Portland
Sat 9/12
7:27 pm-9:54 am
2 stops11h 27m
Knoxville McGhee Tyson
Tue 9/22
6:00 am-2:46 pm
2 stops11h 46m
$455
Cheapest one-way
PortlandKnoxville
PDX Portland - TYS Knoxville McGhee Tyson
PDXTYS
Portland
Fri 9/18
11:08 pm-10:50 am
1 stop8h 42m
$193
PortlandKnoxville
PDX Portland - TYS Knoxville McGhee Tyson
PDXTYS
Portland
Thu 10/15
1:12 pm-11:59 pm
1 stop7h 47m
$207
Quickest one-way
PortlandKnoxville
PDX Portland - TYS Knoxville McGhee Tyson
PDXTYS
Portland
Thu 9/3
7:02 am-4:58 pm
1 stop6h 56m
$208
Showing 1-10 of 17 resultsSorted by cheapest first
Compare providers for flights from Portland to Knoxville
Provider information is updated monthly. Please note that these providers often have deals for this flight, but the availability may vary on a day-by-day basis on Cheapflights.
Use the table below to compare price accuracy, trust ratings, and cancellation policies for each provider offering flight deals from Portland to Knoxville in August.
| Provider | Price Accuracy | Trust Score* |
|---|---|---|
| Price Accuracy1 star | Trust Score*3 stars | |
| Price Accuracy3 stars | Trust Score*3 stars |
- Most accurate provider: When it comes to deals on Portland-Knoxville flights, users find the pricing of FlightHub to be most consistent on Cheapflights vs. FlightHub Users can find the same prices on Portland-Knoxville flight deals on Cheapflights vs. FlightHub >95% of the time. Price accuracy is based on data collected from Portland-Knoxville flight searches over the past month and is updated monthly.
- Most trusted provider: When it comes to deals on Portland-Knoxville flights, Cheapflights users trust FlightHub the most. FlightHub has received a user feedback score of 3 out of 3 stars (3 being the best), meaning they have been trusted the most by Cheapflights users looking for Portland-Knoxville flight deals. Provider user feedback score is based on Cheapflights searches over the past month and is updated monthly.
Best time to book a flight from Portland to Knoxville
Have a flexible travel schedule? Discover the best time to fly to Knoxville from Portland with our price prediction graph.
PDX-TYS
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.
Cheapflights Insights
Everything you need to know about your flight from Portland to Knoxville
How far ahead should I book a flight from Portland to Knoxville?
The best time to book flights from Portland to Knoxville is 68 days before your desired departure date. The cost of your flight will likely increase significantly if you book two weeks in advance of your flight.
What is the cheapest month to book a flight from Portland to Knoxville?
Currently, January is the cheapest month in which you can book a flight from Portland to Knoxville (average of $435). Flying from Portland to Knoxville in May is currently the most expensive (average of $611). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.
How much does it cost to fly round-trip from Portland to Knoxville?
Airfare is below average for this route at the moment.
Portland to Knoxville flights typically cost between $393 and $494 in September.The cheapest round-trip price found within the last 5 days was $299 on American Airlines (Sep 12-Sep 22).
Reviews of airlines servicing Knoxville
Get insights into the airlines that provide service to Knoxville. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Knoxville. Reviews last updated August 17, 2026.
Read through reviews of airlines operating flights from Portland to Knoxville, such as Delta,United Airlines, andAmerican Airlines. Reviews also offer insight into each airline's entertainment options, comfort, food, crew/service, and boarding process.
Comfort
7.8
Food
7.2
Overall
7.8
Boarding
8.1
Entertainment
7.8
Crew
8.5
Reviews
1 / 20
10.0
ExcellentAnonymous,May 2026
SEA - KOA
Comfort
7.8
Food
7.2
Overall
7.8
Boarding
8.1
Entertainment
7.8
Crew
8.5
Reviews
1 / 20
10.0
ExcellentAnonymous,May 2026
SEA - KOA
Comfort
7.8
Food
7.2
Overall
7.8
Boarding
8.1
Entertainment
7.8
Crew
8.5
Reviews
1 / 20
10.0
ExcellentAnonymous,May 2026
SEA - KOA
Comfort
7.8
Food
7.2
Overall
7.8
Boarding
8.1
Entertainment
7.8
Crew
8.5
Reviews
1 / 20
10.0
ExcellentAnonymous,May 2026
SEA - KOA
Related info for your journey
Find useful and relevant information for your journey from Portland to Knoxville. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.
Traveling to a place near Knoxville?
Book flights to Knoxville if you plan to visit one of these locationsCherokee
Crossville
Morristown
Bryson City
Murphy
Alcoa
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Toggle through the tabs below to find thousands of options on Cheapflights for your next trip.
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Complete your trip
Complete your trip to Knoxville by adding a car rental and/or hotel reservation to your travel itinerary.
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Other flights to Knoxville
Explore flights to Knoxville departing from other origins. Flights are based on user searches made on Cheapflights and were last updated on August 17, 2026.
Portland and Knoxville flights
Browse other Portland and Knoxville flight options. Last updated on August 17, 2026.
Other flights from Portland
Browse through other flights departing from Portland. Flights are based on user searches made on Cheapflights and were last updated on August 17, 2026.
Popular flight searches
Check out other popular destinations found by fellow travelers in 2026
Top 3 airlines flying from Portland to Knoxville
Discover the top 3 airlines that operate flights from Portland to Knoxville. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated August 17, 2026.
| Airline | Cheapest | Average | Flexibility | On-time |
|---|---|---|---|---|
| Cheapest$279 | Average$494 | FlexibilityNo cancel fee | On-timeN/A | |
| Cheapest$328 | Average$481 | FlexibilityNo cancel fee | On-time71% | |
| Cheapest$339 | Average$529 | FlexibilityNo cancel fee | On-time69% |