$131+ Cheap flights from Portland to Knoxville (PDX - TYS)
This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 4/29. Fares are subject to change and may not be available on all flights or dates of travel.
PDX — TYS
May 10 — May 171
Round-trip
1 adult, Economy
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Find cheap flights from Portland to Knoxville with Cheapflights
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Enter your travel information like dates, passengers, trip type (one-way or round trip), and preferred cabin class then click “Find deals”2. Select your favorite providers
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Last-minute
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Cheapest flights from Portland to KnoxvilleExplore the most affordable flight options available from Portland to Knoxville. Find the lowest fares from popular airlines and budget airlines, with prices last updated on April 10, 2026.
Explore the most affordable flight options available from Portland to Knoxville. Find the lowest fares from popular airlines and budget airlines, with prices last updated on April 10, 2026.
This American Airlines deal was found by Cheapflights users on 4/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 6/812:40 am
PDX
- TYS
1 stop7h 33m
American Airlines
Tue 6/235:33 pm
TYS
- PDX
1 stop10h 17m
American Airlines
Deal found 4/6![American Airlines logo]()
$375
This American Airlines deal was found by Cheapflights users on 4/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 5/511:48 am
PDX
- TYS
2 stops9h 08m
American Airlines
Tue 5/124:09 pm
TYS
- PDX
1 stop9h 41m
American Airlines
Deal found 4/7![American Airlines logo]()
$380
This American Airlines deal was found by Cheapflights users on 4/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 5/2811:59 am
PDX
- TYS
1 stop8h 57m
American Airlines
Wed 6/35:33 pm
TYS
- PDX
1 stop8h 18m
American Airlines
Deal found 4/6![American Airlines logo]()
$390
This Kiwi.com deal was found by Cheapflights users on 4/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 6/25:46 pm
PDX
- TYS
1 stop22h 47m
Multiple Airlines
Sun 6/72:42 pm
TYS
- PDX
2 stops22h 38m
Multiple Airlines
Deal found 4/8![Multiple Airlines logo]()
$401
This American Airlines deal was found by Cheapflights users on 4/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 6/15:49 am
PDX
- TYS
1 stop8h 48m
American Airlines
Thu 6/45:33 pm
TYS
- PDX
1 stop10h 17m
American Airlines
Deal found 4/5![American Airlines logo]()
$405
This American Airlines deal was found by Cheapflights users on 4/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 4/281:52 pm
PDX
- TYS
1 stop7h 04m
American Airlines
Mon 5/46:54 pm
TYS
- PDX
1 stop8h 00m
American Airlines
Deal found 4/8![American Airlines logo]()
$412
This American Airlines deal was found by Cheapflights users on 4/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 5/291:34 pm
PDX
- TYS
1 stop7h 22m
American Airlines
Wed 6/35:33 pm
TYS
- PDX
1 stop10h 17m
American Airlines
Deal found 4/8![American Airlines logo]()
$416
This Kiwi.com deal was found by Cheapflights users on 4/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 5/88:46 pm
PDX
- TYS
2 stops40h 34m
Multiple Airlines
Fri 5/151:43 pm
TYS
- PDX
1 stop9h 08m
Multiple Airlines
Deal found 4/8![Multiple Airlines logo]()
$423
This American Airlines deal was found by Cheapflights users on 4/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 5/1911:40 pm
PDX
- TYS
1 stop7h 42m
American Airlines
Tue 5/265:33 pm
TYS
- PDX
1 stop10h 17m
American Airlines
Deal found 4/8![American Airlines logo]()
$425
This American Airlines deal was found by Cheapflights users on 4/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 5/711:40 pm
PDX
- TYS
1 stop9h 50m
American Airlines
Fri 5/86:54 pm
TYS
- PDX
1 stop8h 00m
American Airlines
Deal found 4/6![American Airlines logo]()
$431
Best flights from Portland to KnoxvilleDiscover carefully curated flight deals from Portland to Knoxville that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated April 10, 2026.
Discover carefully curated flight deals from Portland to Knoxville that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated April 10, 2026.
This American Airlines deal was found by Cheapflights users on 4/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 6/812:40 am
PDX
- TYS
1 stop9h 23m
American Airlines
Tue 6/235:33 pm
TYS
- PDX
1 stop8h 18m
American Airlines
Deal found 4/4![American Airlines logo]()
$375
This United Airlines deal was found by Cheapflights users on 4/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 4/2910:50 am
PDX
- TYS
1 stop9h 18m
United Airlines
Mon 5/46:01 pm
TYS
- PDX
1 stop8h 54m
United Airlines
Deal found 4/6![United Airlines logo]()
$412
This Delta deal was found by Cheapflights users on 4/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 6/211:12 pm
PDX
- TYS
1 stop8h 09m
Delta
Sun 6/75:25 pm
TYS
- PDX
1 stop7h 25m
Delta
Deal found 4/8![Delta logo]()
$436
This American Airlines deal was found by Cheapflights users on 4/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 5/911:48 am
PDX
- TYS
2 stops9h 08m
American Airlines
Sat 5/165:10 pm
TYS
- PDX
1 stop9h 38m
American Airlines
Deal found 4/4![American Airlines logo]()
$491
This United Airlines deal was found by Cheapflights users on 4/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 4/265:00 am
PDX
- TYS
1 stop7h 06m
United Airlines
Tue 4/282:25 pm
TYS
- PDX
2 stops11h 09m
United Airlines
Deal found 4/6![United Airlines logo]()
$501
This United Airlines deal was found by Cheapflights users on 4/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 5/2811:40 pm
PDX
- TYS
2 stops11h 47m
United Airlines
Wed 6/36:30 am
TYS
- PDX
1 stop8h 08m
United Airlines
Deal found 4/5![United Airlines logo]()
$505
This United Airlines deal was found by Cheapflights users on 4/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 5/2711:40 pm
PDX
- TYS
2 stops11h 47m
United Airlines
Sat 5/305:57 pm
TYS
- PDX
1 stop7h 34m
United Airlines
Deal found 4/6![United Airlines logo]()
$525
This United Airlines deal was found by Cheapflights users on 4/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 6/910:40 pm
PDX
- TYS
2 stops12h 47m
United Airlines
Tue 6/236:30 am
TYS
- PDX
1 stop8h 08m
United Airlines
Deal found 4/4![United Airlines logo]()
$531
This United Airlines deal was found by Cheapflights users on 4/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 5/2411:30 pm
PDX
- TYS
1 stop8h 12m
United Airlines
Thu 5/287:15 am
TYS
- PDX
1 stop7h 41m
United Airlines
Deal found 4/5![United Airlines logo]()
$541
This United Airlines deal was found by Cheapflights users on 4/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 5/55:30 am
PDX
- TYS
3 stops12h 15m
United Airlines
Tue 5/129:50 am
TYS
- PDX
2 stops15h 45m
United Airlines
Deal found 4/7![United Airlines logo]()
$543
Last-minute flights from Portland to KnoxvilleDiscover last-minute flight deals from Portland to Knoxville. Data last updated April 10, 2026 and is based on user searches.
Discover last-minute flight deals from Portland to Knoxville. Data last updated April 10, 2026 and is based on user searches.
This American Airlines deal was found by Cheapflights users on 4/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 4/281:52 pm
PDX
- TYS
1 stop7h 04m
American Airlines
Mon 5/46:54 pm
TYS
- PDX
1 stop8h 00m
American Airlines
Deal found 4/8![American Airlines logo]()
$412
This United Airlines deal was found by Cheapflights users on 4/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 4/2910:50 am
PDX
- TYS
1 stop9h 18m
United Airlines
Mon 5/46:01 pm
TYS
- PDX
1 stop8h 54m
United Airlines
Deal found 4/6![United Airlines logo]()
$432
This American Airlines deal was found by Cheapflights users on 4/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 5/56:00 am
PDX
- TYS
1 stop9h 04m
American Airlines
Tue 5/124:09 pm
TYS
- PDX
1 stop9h 41m
American Airlines
Deal found 4/7![American Airlines logo]()
$375
This American Airlines deal was found by Cheapflights users on 4/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 5/711:40 pm
PDX
- TYS
1 stop9h 50m
American Airlines
Fri 5/86:54 pm
TYS
- PDX
1 stop8h 00m
American Airlines
Deal found 4/6![American Airlines logo]()
$431
This Kiwi.com deal was found by Cheapflights users on 4/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 5/88:46 pm
PDX
- TYS
2 stops40h 34m
Multiple Airlines
Fri 5/151:43 pm
TYS
- PDX
1 stop9h 08m
Multiple Airlines
Deal found 4/8![Multiple Airlines logo]()
$423
This American Airlines deal was found by Cheapflights users on 4/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 5/1911:40 pm
PDX
- TYS
1 stop7h 42m
American Airlines
Tue 5/265:33 pm
TYS
- PDX
1 stop10h 17m
American Airlines
Deal found 4/8![American Airlines logo]()
$425
This American Airlines deal was found by Cheapflights users on 4/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 5/2811:59 am
PDX
- TYS
1 stop8h 57m
American Airlines
Wed 6/35:33 pm
TYS
- PDX
1 stop8h 18m
American Airlines
Deal found 4/6![American Airlines logo]()
$390
This American Airlines deal was found by Cheapflights users on 4/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 5/291:34 pm
PDX
- TYS
1 stop7h 22m
American Airlines
Wed 6/35:33 pm
TYS
- PDX
1 stop10h 17m
American Airlines
Deal found 4/8![American Airlines logo]()
$416
One-way flights from Portland to KnoxvilleSearch for one-way flight options from Portland to Knoxville. Find affordable one-way fares based on user searches. Data last updated April 10, 2026.
Search for one-way flight options from Portland to Knoxville. Find affordable one-way fares based on user searches. Data last updated April 10, 2026.
This Booking.com deal was found by Cheapflights users on 4/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Booking.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 4/2912:38 pm
PDX
- TYS
1 stop23h 55m
Frontier
Deal found 4/6![Frontier logo]()
$131
This Kiwi.com deal was found by Cheapflights users on 4/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 6/111:15 am
PDX
- TYS
3 stops52h 06m
Multiple Airlines
Deal found 4/8![Multiple Airlines logo]()
$177
This Kiwi.com deal was found by Cheapflights users on 4/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 4/2912:38 pm
PDX
- TYS
3 stops28h 57m
Multiple Airlines
Deal found 4/6![Multiple Airlines logo]()
$190
This Southwest deal was found by Cheapflights users on 4/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 4/296:30 am
PDX
- TYS
2 stops11h 20m
Southwest
Deal found 4/6![Southwest logo]()
$193
This American Airlines deal was found by Cheapflights users on 4/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 6/109:47 pm
PDX
- TYS
1 stop9h 49m
American Airlines
Deal found 4/4![American Airlines logo]()
$201
This American Airlines deal was found by Cheapflights users on 4/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 5/411:40 pm
PDX
- TYS
1 stop9h 50m
American Airlines
Deal found 4/6![American Airlines logo]()
$203
This Kiwi.com deal was found by Cheapflights users on 4/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 5/295:31 pm
PDX
- TYS
3 stops47h 58m
Multiple Airlines
Deal found 4/8![Multiple Airlines logo]()
$204
This United Airlines deal was found by Cheapflights users on 4/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 5/3011:05 am
PDX
- TYS
2 stops10h 25m
United Airlines
Deal found 4/8![United Airlines logo]()
$208
This Kiwi.com deal was found by Cheapflights users on 4/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 5/299:22 am
PDX
- TYS
2 stops33h 35m
Allegiant Air
Deal found 4/8![Allegiant Air logo]()
$211
This Booking.com deal was found by Cheapflights users on 4/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Booking.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 5/1412:35 pm
PDX
- TYS
1 stop27h 58m
Frontier
Deal found 4/8![Frontier logo]()
$213
This Kiwi.com deal was found by Cheapflights users on 4/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 5/19:54 am
PDX
- TYS
3 stops29h 09m
Multiple Airlines
Deal found 4/6![Multiple Airlines logo]()
$215
Find flight deals from Portland to Knoxville
Discover tips and strategies to find the most affordable flight options for your journey from Portland (PDX) to Knoxville (TYS). Learn about various techniques such as flexible date searches, comparing prices across and setting up price alerts. Use these methods to find the cheapest flights available for your travel needs. Data last updated April 10, 2026.
Most accurate provider | FlightHub 3 stars |
|---|---|
Most trusted provider | FlightHub 3 stars |
Round-trip from | $375 (American Airlines) |
One-way from | $131 (Booking.com) |
Popular in | March |
Cheapest in | August |
Average price | $458 |
Cheapflights Fare Finder
Customize your flight search to find flights from Portland to Knoxville that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated April 10, 2026.
Use the filters below to find and compare flights from Portland to Knoxville that are best for you.
Fly from
Fly to
Route
Depart
Return
Cheapest round-trip
PortlandKnoxville
PDX - TYS
PDXTYS
Portland
Mon 6/8
12:40 am-1:03 pm
1 stop9h 23m
Knoxville McGhee Tyson
Tue 6/23
5:33 pm-10:51 pm
1 stop8h 18m
$375
PortlandKnoxville
PDX - TYS
PDXTYS
Portland
Wed 4/29
10:50 am-11:08 pm
1 stop9h 18m
Knoxville McGhee Tyson
Mon 5/4
6:01 pm-11:55 pm
1 stop8h 54m
$412
Quickest round-trip
PortlandKnoxville
PDX - TYS
PDXTYS
Portland
Tue 6/2
11:12 pm-10:21 am
1 stop8h 09m
Knoxville McGhee Tyson
Sun 6/7
5:25 pm-9:50 pm
1 stop7h 25m
$436
PortlandKnoxville
PDX - TYS
PDXTYS
Portland
Sat 5/9
11:48 am-11:56 pm
2 stops9h 08m
Knoxville McGhee Tyson
Sat 5/16
5:10 pm-11:48 pm
1 stop9h 38m
$491
PortlandKnoxville
PDX - TYS
PDXTYS
Portland
Sun 4/26
5:00 am-3:06 pm
1 stop7h 06m
Knoxville McGhee Tyson
Tue 4/28
2:25 pm-10:34 pm
2 stops11h 09m
$501
PortlandKnoxville
PDX - TYS
PDXTYS
Portland
Thu 5/28
11:40 pm-2:27 pm
2 stops11h 47m
Knoxville McGhee Tyson
Wed 6/3
6:30 am-11:38 am
1 stop8h 08m
$505
PortlandKnoxville
PDX - TYS
PDXTYS
Portland
Wed 5/27
11:40 pm-2:27 pm
2 stops11h 47m
Knoxville McGhee Tyson
Sat 5/30
5:57 pm-10:31 pm
1 stop7h 34m
$525
PortlandKnoxville
PDX - TYS
PDXTYS
Portland
Tue 6/9
10:40 pm-2:27 pm
2 stops12h 47m
Knoxville McGhee Tyson
Tue 6/23
6:30 am-11:38 am
1 stop8h 08m
$531
PortlandKnoxville
PDX - TYS
PDXTYS
Portland
Sun 5/24
11:30 pm-10:42 am
1 stop8h 12m
Knoxville McGhee Tyson
Thu 5/28
7:15 am-11:56 am
1 stop7h 41m
$541
PortlandKnoxville
PDX - TYS
PDXTYS
Portland
Tue 5/5
5:30 am-8:45 pm
3 stops12h 15m
Knoxville McGhee Tyson
Tue 5/12
9:50 am-10:35 pm
2 stops15h 45m
$543
Showing 1-10 of 21 resultsSorted by cheapest first
Compare providers for flights from Portland to Knoxville
Provider information is updated monthly. Please note that these providers often have deals for this flight, but the availability may vary on a day-by-day basis on Cheapflights.
Use the table below to compare price accuracy, trust ratings, and cancellation policies for each provider offering flight deals from Portland to Knoxville in April.
| Provider | Price Accuracy | Trust Score* |
|---|---|---|
| Price Accuracy1 star | Trust Score*3 stars | |
| Price Accuracy3 stars | Trust Score*3 stars |
- Most accurate provider: When it comes to deals on Portland-Knoxville flights, users find the pricing of FlightHub to be most consistent on Cheapflights vs. FlightHub Users can find the same prices on Portland-Knoxville flight deals on Cheapflights vs. FlightHub >95% of the time. Price accuracy is based on data collected from Portland-Knoxville flight searches over the past month and is updated monthly.
- Most trusted provider: When it comes to deals on Portland-Knoxville flights, Cheapflights users trust FlightHub the most. FlightHub has received a user feedback score of 3 out of 3 stars (3 being the best), meaning they have been trusted the most by Cheapflights users looking for Portland-Knoxville flight deals. Provider user feedback score is based on Cheapflights searches over the past month and is updated monthly.
Best time to book a flight from Portland to Knoxville
Have a flexible travel schedule? Discover the best time to fly to Knoxville from Portland with our price prediction graph.
PDX-TYS
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.
Cheapflights Insights
Everything you need to know about your flight from Portland to Knoxville
How far ahead should I book a flight from Portland to Knoxville?
Use this chart to determine the optimal time to book a round-trip flight from Portland to Knoxville. Price data was last updated on April 3, 2026.
The best time to book flights from Portland to Knoxville is 75 days before your desired departure date. The cost of your flight will likely increase significantly if you book two weeks in advance of your flight.
What is the cheapest month to book a flight from Portland to Knoxville?
Currently, July is the cheapest month in which you can book a flight from Portland to Knoxville (average of $126). Flying from Portland to Knoxville in May is currently the most expensive (average of $313). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.
How much does it cost to fly round-trip from Portland to Knoxville?
Reviews of airlines servicing Knoxville
Get insights into the airlines that provide service to Knoxville. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Knoxville. Reviews last updated April 10, 2026.
Read through reviews of airlines operating flights from Portland to Knoxville, such as Delta,United Airlines, andAmerican Airlines. Reviews also offer insight into each airline's entertainment options, comfort, food, crew/service, and boarding process.
Crew
8.5
Overall
7.9
Comfort
7.9
Boarding
8.1
Food
7.2
Entertainment
7.8
Reviews
1 / 20
6.0
GoodJim,Nov 2025
AVL - ATL
Crew
8.5
Overall
7.9
Comfort
7.9
Boarding
8.1
Food
7.2
Entertainment
7.8
Reviews
1 / 20
6.0
GoodJim,Nov 2025
AVL - ATL
Crew
8.5
Overall
7.9
Comfort
7.9
Boarding
8.1
Food
7.2
Entertainment
7.8
Reviews
1 / 20
6.0
GoodJim,Nov 2025
AVL - ATL
Crew
8.5
Overall
7.9
Comfort
7.9
Boarding
8.1
Food
7.2
Entertainment
7.8
Reviews
1 / 20
6.0
GoodJim,Nov 2025
AVL - ATL
Crew
8.5
Overall
7.9
Comfort
7.9
Boarding
8.1
Food
7.2
Entertainment
7.8
Reviews
1 / 20
6.0
GoodJim,Nov 2025
AVL - ATL
Related info for your journey
Find useful and relevant information for your journey from Portland to Knoxville. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.
Traveling to a place near Knoxville?
Book flights to Knoxville if you plan to visit one of these locationsCherokee
Crossville
Corbin
Morristown
Bryson City
Alcoa
Murphy
Oak Ridge
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Other flights to Knoxville
Explore flights to Knoxville departing from other origins. Flights are based on user searches made on Cheapflights and were last updated on April 10, 2026.
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Top 4 airlines flying from Portland to Knoxville
Discover the top 4 airlines that operate flights from Portland to Knoxville. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated April 10, 2026.
| Airline | Cheapest | Average | Flexibility | On-time |
|---|---|---|---|---|
| Cheapest$256 | Average$428 | FlexibilityNo cancel fee | On-timeN/A | |
| Cheapest$264 | Average$343 | FlexibilityNo cancel fee | On-time62% | |
| Cheapest$279 | Average$493 | FlexibilityNo cancel fee | On-time69% | |
| Cheapest$303 | Average$455 | FlexibilityNo cancel fee | On-time71% |