$152+ Cheap flights from Portland to Knoxville (PDX - TYS)
This is the cheapest round-trip flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 9/24. Fares are subject to change and may not be available on all flights or dates of travel.
PDX — TYS
Oct 7 — Oct 141
Round-trip
1 adult, Economy
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Find cheap flights from Portland to Knoxville with Cheapflights
1. Tell us where you want to go
Enter your travel information like dates, passengers, trip type (one-way or round trip), and preferred cabin class then click “Find deals”2. Select your favorite providers
We find the providers serving your travel needs. Choose up to four travel providers to compare side-by-side for flights, hotels, or car rentals.3. Compare prices and book
Review each provider’s pricing and select the best option for you! Book through your favorite provider’s website for a seamless experience.Cheap flight deals from Portland to Knoxville
Cheapest
Best
Last-minute
One-way
Cheapest flights from Portland to KnoxvilleExplore the most affordable flight options available from Portland to Knoxville. Find the lowest fares from popular airlines and budget airlines, with prices last updated on September 7, 2026.
Explore the most affordable flight options available from Portland to Knoxville. Find the lowest fares from popular airlines and budget airlines, with prices last updated on September 7, 2026.
This American Airlines deal was found by Cheapflights users on 9/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 10/1210:55 pm -
1 stop9h 10m
Thu 10/156:55 pm -
1 stop8h 04m
Deal found 9/3![American Airlines logo]()
$363
This United Airlines deal was found by Cheapflights users on 9/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 11/311:30 pm -
2 stops9h 00m
Thu 11/126:45 am -
1 stop8h 02m
Deal found 9/2![United Airlines logo]()
$368
This American Airlines deal was found by Cheapflights users on 9/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 10/311:08 pm -
2 stops10h 19m
Sat 10/106:55 pm -
1 stop8h 04m
Deal found 9/3![American Airlines logo]()
$377
This Southwest deal was found by Cheapflights users on 9/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 11/36:55 am -
2 stops9h 50m
Thu 11/127:05 am -
2 stops16h 15m
Deal found 9/2![Southwest logo]()
$379
This American Airlines deal was found by Cheapflights users on 9/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 10/312:01 pm -
1 stop8h 21m
Mon 10/123:56 pm -
1 stop10h 09m
Deal found 9/3![American Airlines logo]()
$397
This Southwest deal was found by Cheapflights users on 9/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 10/2711:35 pm -
2 stops9h 45m
Mon 11/23:40 pm -
2 stops11h 30m
Deal found 9/3![Southwest logo]()
$403
This Kiwi.com deal was found by Cheapflights users on 9/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 11/512:02 pm -
2 stops27h 04m
Sun 11/86:30 am -
1 stop7h 42m
Deal found 9/4![Multiple Airlines logo]()
$413
This American Airlines deal was found by Cheapflights users on 9/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 10/411:06 pm -
1 stop8h 17m
Tue 10/66:55 pm -
1 stop8h 04m
Deal found 9/2![American Airlines logo]()
$415
This Southwest deal was found by Cheapflights users on 9/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 10/411:35 pm -
2 stops9h 40m
Tue 10/64:20 pm -
1 stop8h 55m
Deal found 9/2![Southwest logo]()
$420
Best flights from Portland to KnoxvilleDiscover carefully curated flight deals from Portland to Knoxville that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated September 7, 2026.
Discover carefully curated flight deals from Portland to Knoxville that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated September 7, 2026.
This American Airlines deal was found by Cheapflights users on 9/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/291:12 pm -
1 stop7h 47m
Sun 11/15:32 pm -
1 stop9h 11m
Deal found 9/2![American Airlines logo]()
$415
This United Airlines deal was found by Cheapflights users on 9/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 10/1811:30 pm -
1 stop7h 15m
Sat 10/246:00 am -
2 stops10h 15m
Deal found 9/3![United Airlines logo]()
$420
This Southwest deal was found by Cheapflights users on 9/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 9/295:50 am -
2 stops10h 10m
Wed 10/74:20 pm -
2 stops10h 20m
Deal found 9/4![Southwest logo]()
$447
This Kiwi.com deal was found by Cheapflights users on 9/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/2912:02 pm -
2 stops30h 47m
Sun 11/16:30 am -
1 stop7h 42m
Deal found 9/2![Multiple Airlines logo]()
$457
This Delta deal was found by Cheapflights users on 9/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 10/138:44 pm -
2 stops10h 36m
Thu 10/2212:06 pm -
1 stop10h 03m
Deal found 9/5![Delta logo]()
$522
This United Airlines deal was found by Cheapflights users on 9/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 10/1311:30 pm -
1 stop7h 15m
Thu 10/2212:05 pm -
1 stop10h 11m
Deal found 9/5![United Airlines logo]()
$437
This Southwest deal was found by Cheapflights users on 9/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/307:50 pm -
2 stops11h 00m
Mon 11/25:25 pm -
1 stop8h 15m
Deal found 9/6![Southwest logo]()
$452
This American Airlines deal was found by Cheapflights users on 9/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 9/207:25 am -
1 stop9h 49m
Fri 9/254:48 pm -
1 stop10h 19m
Deal found 9/2![American Airlines logo]()
$505
This Southwest deal was found by Cheapflights users on 9/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/298:50 am -
2 stops10h 55m
Sun 11/17:05 am -
2 stops16h 55m
Deal found 9/2![Southwest logo]()
$461
This Southwest deal was found by Cheapflights users on 9/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 10/146:15 am -
2 stops10h 55m
Thu 10/225:30 pm -
1 stop8h 15m
Deal found 9/6![Southwest logo]()
$467
This Southwest deal was found by Cheapflights users on 9/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 10/176:30 am -
2 stops8h 25m
Sat 10/246:40 am -
2 stops9h 45m
Deal found 9/4![Southwest logo]()
$492
This Southwest deal was found by Cheapflights users on 9/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 11/85:10 am -
2 stops10h 35m
Thu 11/127:05 am -
2 stops16h 15m
Deal found 9/7![Southwest logo]()
$498
Last-minute flights from Portland to KnoxvilleDiscover last-minute flight deals from Portland to Knoxville. Data last updated September 7, 2026 and is based on user searches.
Discover last-minute flight deals from Portland to Knoxville. Data last updated September 7, 2026 and is based on user searches.
This United Airlines deal was found by Cheapflights users on 9/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 9/3010:43 am -
1 stop7h 06m
Tue 10/610:42 am -
2 stops10h 05m
Deal found 9/2![United Airlines logo]()
$368
This American Airlines deal was found by Cheapflights users on 9/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 10/311:08 pm -
2 stops10h 19m
Sat 10/106:55 pm -
1 stop8h 04m
Deal found 9/3![American Airlines logo]()
$377
This American Airlines deal was found by Cheapflights users on 9/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 10/312:01 pm -
1 stop8h 21m
Mon 10/123:56 pm -
1 stop10h 09m
Deal found 9/3![American Airlines logo]()
$397
This American Airlines deal was found by Cheapflights users on 9/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 10/411:06 pm -
1 stop8h 17m
Tue 10/66:55 pm -
1 stop8h 04m
Deal found 9/2![American Airlines logo]()
$415
This Southwest deal was found by Cheapflights users on 9/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 10/411:35 pm -
2 stops9h 40m
Tue 10/64:20 pm -
1 stop8h 55m
Deal found 9/2![Southwest logo]()
$420
This Southwest deal was found by Cheapflights users on 9/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 10/55:00 am -
2 stops14h 45m
Wed 10/144:20 pm -
1 stop8h 55m
Deal found 9/3![Southwest logo]()
$434
This United Airlines deal was found by Cheapflights users on 9/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 10/148:25 am -
1 stop8h 54m
Thu 10/156:00 am -
1 stop8h 33m
Deal found 9/6![United Airlines logo]()
$432
This American Airlines deal was found by Cheapflights users on 9/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 10/171:12 pm -
1 stop7h 47m
Tue 10/206:55 pm -
1 stop8h 04m
Deal found 9/2![American Airlines logo]()
$363
This American Airlines deal was found by Cheapflights users on 9/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 10/1710:55 pm -
1 stop9h 10m
Sat 10/243:00 pm -
1 stop9h 11m
Deal found 9/4![American Airlines logo]()
$437
This Southwest deal was found by Cheapflights users on 9/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 10/2711:35 pm -
2 stops9h 45m
Mon 11/23:40 pm -
2 stops11h 30m
Deal found 9/3![Southwest logo]()
$403
One-way flights from Portland to KnoxvilleSearch for one-way flight options from Portland to Knoxville. Find affordable one-way fares based on user searches. Data last updated September 7, 2026.
Search for one-way flight options from Portland to Knoxville. Find affordable one-way fares based on user searches. Data last updated September 7, 2026.
This Kiwi.com deal was found by Cheapflights users on 9/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 9/2412:38 pm -
2 stops31h 43m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 9/3![Multiple Airlines logo]()
$152
This Kiwi.com deal was found by Cheapflights users on 9/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 10/412:38 pm -
2 stops29h 00m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 9/3![Multiple Airlines logo]()
$159
This Delta deal was found by Cheapflights users on 9/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 9/1111:35 am -
1 stop8h 39m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 9/2![Delta logo]()
$169
This United Airlines deal was found by Cheapflights users on 9/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 9/3010:43 am -
1 stop7h 06m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 9/3![United Airlines logo]()
$182
This Kiwi.com deal was found by Cheapflights users on 9/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 10/511:02 am -
2 stops22h 58m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 9/3![Multiple Airlines logo]()
$189
This American Airlines deal was found by Cheapflights users on 9/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/3010:55 pm -
1 stop9h 10m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 9/3![American Airlines logo]()
$212
This Kiwi.com deal was found by Cheapflights users on 9/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/3012:31 pm -
3 stops46h 40m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 9/3![Multiple Airlines logo]()
$215
This Southwest deal was found by Cheapflights users on 9/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/308:20 pm -
2 stops10h 30m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 9/3![Southwest logo]()
$217
This United Airlines deal was found by Cheapflights users on 9/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 10/1411:30 pm -
1 stop7h 15m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 9/6![United Airlines logo]()
$219
This United Airlines deal was found by Cheapflights users on 9/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 9/105:00 am -
1 stop7h 54m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 9/2![United Airlines logo]()
$224
Find flight deals from Portland to Knoxville
Discover tips and strategies to find the most affordable flight options for your journey from Portland (PDX) to Knoxville (TYS). Learn about various techniques such as flexible date searches, comparing prices across and setting up price alerts. Use these methods to find the cheapest flights available for your travel needs. Data last updated September 7, 2026.
Most accurate provider | FlightHub 3 stars |
|---|---|
Most trusted provider | FlightHub 3 stars |
Round-trip from | $363 (American Airlines) |
One-way from | $152 (Kiwi.com) |
Popular in | May |
Cheapest in | January |
Average price | $436 |
Cheapflights Fare Finder
Customize your flight search to find flights from Portland to Knoxville that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 7,457,451 searches. Data last updated September 7, 2026.
Use the filters below to find and compare flights from Portland to Knoxville that are best for you.
Fly from
Fly to
Route
Depart
Return
Cheapest round-trip
Quickest round-trip
PortlandKnoxville
PDX Portland - TYS Knoxville McGhee Tyson
PDXTYS
Portland
Wed 9/30
10:43 am-8:49 pm
1 stop7h 06m
Knoxville McGhee Tyson
Wed 12/31
12:00 am-9:00 pm
Nonstop0h 00m
$182
PortlandKnoxville
PDX Portland - TYS Knoxville McGhee Tyson
PDXTYS
Portland
Fri 10/30
8:20 pm-9:50 am
2 stops10h 30m
Knoxville McGhee Tyson
Wed 12/31
12:00 am-9:00 pm
Nonstop0h 00m
$217
PortlandKnoxville
PDX Portland - TYS Knoxville McGhee Tyson
PDXTYS
Portland
Wed 10/14
11:30 pm-9:45 am
1 stop7h 15m
Knoxville McGhee Tyson
Wed 12/31
12:00 am-9:00 pm
Nonstop0h 00m
$219
PortlandKnoxville
PDX Portland - TYS Knoxville McGhee Tyson
PDXTYS
Portland
Thu 9/10
5:00 am-3:54 pm
1 stop7h 54m
Knoxville McGhee Tyson
Wed 12/31
12:00 am-9:00 pm
Nonstop0h 00m
$224
PortlandKnoxville
PDX Portland - TYS Knoxville McGhee Tyson
PDXTYS
Portland
Wed 9/30
11:08 pm-12:01 pm
2 stops9h 53m
Knoxville McGhee Tyson
Wed 12/31
12:00 am-9:00 pm
Nonstop0h 00m
$229
PortlandKnoxville
PDX Portland - TYS Knoxville McGhee Tyson
PDXTYS
Portland
Sun 10/18
10:55 pm-11:05 am
1 stop9h 10m
Knoxville McGhee Tyson
Wed 12/31
12:00 am-9:00 pm
Nonstop0h 00m
$234
PortlandKnoxville
PDX Portland - TYS Knoxville McGhee Tyson
PDXTYS
Portland
Sun 10/11
11:30 pm-9:45 am
1 stop7h 15m
Knoxville McGhee Tyson
Wed 12/31
12:00 am-9:00 pm
Nonstop0h 00m
$244
PortlandKnoxville
PDX Portland - TYS Knoxville McGhee Tyson
PDXTYS
Portland
Tue 10/6
7:09 am-11:59 pm
2 stops13h 50m
Knoxville McGhee Tyson
Wed 12/31
12:00 am-9:00 pm
Nonstop0h 00m
$320
PortlandKnoxville
PDX Portland - TYS Knoxville McGhee Tyson
PDXTYS
Portland
Tue 9/22
9:46 pm-5:18 pm
3 stops40h 32m
Knoxville McGhee Tyson
Wed 12/31
12:00 am-9:00 pm
Nonstop0h 00m
$391
PortlandKnoxville
PDX Portland - TYS Knoxville McGhee Tyson
PDXTYS
Portland
Thu 10/29
1:12 pm-11:59 pm
1 stop7h 47m
Knoxville McGhee Tyson
Sun 11/1
5:32 pm-11:43 pm
1 stop9h 11m
$415
Showing 1-10 of 21 resultsSorted by cheapest first
Compare providers for flights from Portland to Knoxville
Provider information is updated monthly. Please note that these providers often have deals for this flight, but the availability may vary on a day-by-day basis on Cheapflights.
Use the table below to compare price accuracy, trust ratings, and cancellation policies for each provider offering flight deals from Portland to Knoxville in September.
| Provider | Price Accuracy | Trust Score* |
|---|---|---|
| Price Accuracy1 star | Trust Score*3 stars | |
| Price Accuracy3 stars | Trust Score*3 stars |
- Most accurate provider: When it comes to deals on Portland-Knoxville flights, users find the pricing of FlightHub to be most consistent on Cheapflights vs. FlightHub Users can find the same prices on Portland-Knoxville flight deals on Cheapflights vs. FlightHub >95% of the time. Price accuracy is based on data collected from Portland-Knoxville flight searches over the past month and is updated monthly.
- Most trusted provider: When it comes to deals on Portland-Knoxville flights, Cheapflights users trust FlightHub the most. FlightHub has received a user feedback score of 3 out of 3 stars (3 being the best), meaning they have been trusted the most by Cheapflights users looking for Portland-Knoxville flight deals. Provider user feedback score is based on Cheapflights searches over the past month and is updated monthly.
Best time to book a flight from Portland to Knoxville
Have a flexible travel schedule? Discover the best time to fly to Knoxville from Portland with our price prediction graph.
PDX-TYS
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.
Cheapflights Insights
Everything you need to know about your flight from Portland to Knoxville
How far ahead should I book a flight from Portland to Knoxville?
The best time to book flights from Portland to Knoxville is 20 days before your desired departure date. The cost of your flight will likely increase significantly if you book two weeks in advance of your flight.
What is the cheapest month to book a flight from Portland to Knoxville?
Currently, January is the cheapest month in which you can book a flight from Portland to Knoxville (average of $435). Flying from Portland to Knoxville in May is currently the most expensive (average of $611). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.
How much does it cost to fly round-trip from Portland to Knoxville?
Airfare is below average for this route at the moment.
Portland to Knoxville flights typically cost between $383 and $620 in October.The cheapest round-trip price found within the last 5 days was $363 on American Airlines (Oct 12-Oct 15).
Reviews of airlines servicing Knoxville
Get insights into the airlines that provide service to Knoxville. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Knoxville. Reviews last updated September 7, 2026.
Read through reviews of airlines operating flights from Portland to Knoxville, such as Delta,United Airlines, andAmerican Airlines. Reviews also offer insight into each airline's entertainment options, comfort, food, crew/service, and boarding process.
Boarding
8.1
Comfort
7.8
Crew
8.5
Food
7.2
Entertainment
7.8
Overall
7.8
Reviews
1 / 20
8.0
ExcellentJorge,Aug 2026
TPA - ATL
Boarding
8.1
Comfort
7.8
Crew
8.5
Food
7.2
Entertainment
7.8
Overall
7.8
Reviews
1 / 20
8.0
ExcellentJorge,Aug 2026
TPA - ATL
Boarding
8.1
Comfort
7.8
Crew
8.5
Food
7.2
Entertainment
7.8
Overall
7.8
Reviews
1 / 20
8.0
ExcellentJorge,Aug 2026
TPA - ATL
Boarding
8.1
Comfort
7.8
Crew
8.5
Food
7.2
Entertainment
7.8
Overall
7.8
Reviews
1 / 20
8.0
ExcellentJorge,Aug 2026
TPA - ATL
Related info for your journey
Find useful and relevant information for your journey from Portland to Knoxville. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.
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Top 3 airlines flying from Portland to Knoxville
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| Airline | Cheapest | Average | Flexibility | On-time |
|---|---|---|---|---|
| Cheapest$279 | Average$497 | FlexibilityNo cancel fee | On-timeN/A | |
| Cheapest$328 | Average$486 | FlexibilityNo cancel fee | On-time71% | |
| Cheapest$358 | Average$537 | FlexibilityNo cancel fee | On-time69% |