$116+ Cheap flights from Portland to Knoxville (PDX - TYS)
This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 4/18. Fares are subject to change and may not be available on all flights or dates of travel.
PDX — TYS
Apr 14 — Apr 211
Round-trip
1 adult, Economy
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Find cheap flights from Portland to Knoxville with Cheapflights
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Enter your travel information like dates, passengers, trip type (one-way or round trip), and preferred cabin class then click “Find deals”2. Select your favorite providers
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Review each provider’s pricing and select the best option for you! Book through your favorite provider’s website for a seamless experience.Cheap flight deals from Portland to Knoxville
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Best
Last-minute
One-way
Cheapest flights from Portland to KnoxvilleExplore the most affordable flight options available from Portland to Knoxville. Find the lowest fares from popular airlines and budget airlines, with prices last updated on March 15, 2026.
Explore the most affordable flight options available from Portland to Knoxville. Find the lowest fares from popular airlines and budget airlines, with prices last updated on March 15, 2026.
This Booking.com deal was found by Cheapflights users on 3/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Booking.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 6/412:35 pm
PDX
- TYS
1 stop27h 58m
Frontier
Mon 6/158:08 pm
TYS
- PDX
1 stop18h 05m
Frontier
Deal found 3/13![Frontier logo]()
$302
This Gotogate deal was found by Cheapflights users on 3/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Gotogate is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 6/912:23 pm
PDX
- TYS
1 stop27h 50m
Frontier
Mon 6/158:08 pm
TYS
- PDX
1 stop18h 05m
Frontier
Deal found 3/12![Frontier logo]()
$320
This American Airlines deal was found by Cheapflights users on 3/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 4/81:52 pm
PDX
- TYS
1 stop7h 04m
American Airlines
Wed 4/154:09 pm
TYS
- PDX
1 stop9h 40m
American Airlines
Deal found 3/11![American Airlines logo]()
$359
This Kiwi.com deal was found by Cheapflights users on 3/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 4/1512:28 pm
PDX
- TYS
1 stop24h 05m
Multiple Airlines
Mon 4/206:20 pm
TYS
- PDX
2 stops44h 32m
Multiple Airlines
Deal found 3/12![Multiple Airlines logo]()
$360
This Kiwi.com deal was found by Cheapflights users on 3/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 4/128:39 pm
PDX
- TYS
2 stops15h 49m
Frontier
Thu 4/164:28 pm
TYS
- PDX
1 stop21h 35m
Frontier
Deal found 3/12![Frontier logo]()
$363
This Booking.com deal was found by Cheapflights users on 3/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Booking.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 4/1812:27 pm
PDX
- TYS
1 stop24h 06m
Frontier
Sun 4/264:28 pm
TYS
- PDX
1 stop21h 35m
Frontier
Deal found 3/13![Frontier logo]()
$368
This American Airlines deal was found by Cheapflights users on 3/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 4/2712:59 am
PDX
- TYS
1 stop8h 31m
American Airlines
Sat 5/22:06 pm
TYS
- PDX
1 stop9h 57m
American Airlines
Deal found 3/10![American Airlines logo]()
$372
This United Airlines deal was found by Cheapflights users on 3/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 4/145:00 am
PDX
- TYS
1 stop7h 06m
United Airlines
Sat 4/189:40 am
TYS
- PDX
2 stops11h 54m
United Airlines
Deal found 3/12![United Airlines logo]()
$377
This Delta deal was found by Cheapflights users on 3/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 4/711:15 pm
PDX
- TYS
1 stop8h 16m
Delta
Wed 4/85:24 pm
TYS
- PDX
1 stop7h 29m
Delta
Deal found 3/12![Delta logo]()
$379
Best flights from Portland to KnoxvilleDiscover carefully curated flight deals from Portland to Knoxville that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated March 15, 2026.
Discover carefully curated flight deals from Portland to Knoxville that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated March 15, 2026.
This Delta deal was found by Cheapflights users on 3/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 4/136:05 pm
PDX
- TYS
2 stops12h 17m
Delta
Wed 4/155:26 pm
TYS
- PDX
2 stops9h 30m
Delta
Deal found 3/14![Delta logo]()
$426
This United Airlines deal was found by Cheapflights users on 3/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 7/2111:40 pm
PDX
- TYS
1 stop6h 53m
United Airlines
Tue 7/288:20 am
TYS
- PDX
2 stops9h 53m
United Airlines
Deal found 3/13![United Airlines logo]()
$462
This Delta deal was found by Cheapflights users on 3/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 9/911:39 am
PDX
- TYS
1 stop8h 17m
Delta
Sat 9/194:00 pm
TYS
- PDX
2 stops10h 41m
Delta
Deal found 3/10![Delta logo]()
$462
This United Airlines deal was found by Cheapflights users on 3/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 4/148:05 am
PDX
- TYS
1 stop8h 37m
United Airlines
Sat 4/188:30 am
TYS
- PDX
2 stops12h 38m
United Airlines
Deal found 3/12![United Airlines logo]()
$477
This Delta deal was found by Cheapflights users on 3/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 7/319:45 pm
PDX
- TYS
1 stop8h 26m
Delta
Thu 8/65:15 pm
TYS
- PDX
1 stop7h 31m
Delta
Deal found 3/14![Delta logo]()
$477
This United Airlines deal was found by Cheapflights users on 3/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 6/911:16 am
PDX
- TYS
2 stops10h 14m
United Airlines
Mon 6/155:57 pm
TYS
- PDX
1 stop8h 56m
United Airlines
Deal found 3/12![United Airlines logo]()
$487
This United Airlines deal was found by Cheapflights users on 3/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 6/92:12 pm
PDX
- TYS
1 stop7h 18m
United Airlines
Tue 6/235:45 am
TYS
- PDX
2 stops13h 11m
United Airlines
Deal found 3/10![United Airlines logo]()
$513
This Delta deal was found by Cheapflights users on 3/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 5/1011:02 pm
PDX
- TYS
1 stop8h 19m
Delta
Wed 5/201:57 pm
TYS
- PDX
2 stops10h 55m
Delta
Deal found 3/11![Delta logo]()
$513
Last-minute flights from Portland to KnoxvilleDiscover last-minute flight deals from Portland to Knoxville. Data last updated March 15, 2026 and is based on user searches.
Discover last-minute flight deals from Portland to Knoxville. Data last updated March 15, 2026 and is based on user searches.
This United Airlines deal was found by Cheapflights users on 3/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 4/65:00 am
PDX
- TYS
1 stop7h 06m
United Airlines
Sat 4/117:00 am
TYS
- PDX
1 stop7h 44m
United Airlines
Deal found 3/12![United Airlines logo]()
$385
This Delta deal was found by Cheapflights users on 3/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 4/711:15 pm
PDX
- TYS
1 stop8h 16m
Delta
Wed 4/85:24 pm
TYS
- PDX
1 stop7h 29m
Delta
Deal found 3/12![Delta logo]()
$379
This American Airlines deal was found by Cheapflights users on 3/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 4/81:52 pm
PDX
- TYS
1 stop7h 04m
American Airlines
Wed 4/154:09 pm
TYS
- PDX
1 stop9h 40m
American Airlines
Deal found 3/11![American Airlines logo]()
$359
This Kiwi.com deal was found by Cheapflights users on 3/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 4/128:39 pm
PDX
- TYS
2 stops15h 49m
Frontier
Thu 4/164:28 pm
TYS
- PDX
1 stop21h 35m
Frontier
Deal found 3/12![Frontier logo]()
$363
This United Airlines deal was found by Cheapflights users on 3/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 4/145:00 am
PDX
- TYS
1 stop7h 06m
United Airlines
Sat 4/189:40 am
TYS
- PDX
2 stops11h 54m
United Airlines
Deal found 3/12![United Airlines logo]()
$377
This Kiwi.com deal was found by Cheapflights users on 3/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 4/141:48 pm
PDX
- TYS
2 stops22h 47m
Multiple Airlines
Thu 4/168:00 am
TYS
- PDX
1 stop13h 56m
Multiple Airlines
Deal found 3/12![Multiple Airlines logo]()
$383
This Kiwi.com deal was found by Cheapflights users on 3/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 4/1512:28 pm
PDX
- TYS
1 stop24h 05m
Multiple Airlines
Mon 4/206:20 pm
TYS
- PDX
2 stops44h 32m
Multiple Airlines
Deal found 3/12![Multiple Airlines logo]()
$360
This Booking.com deal was found by Cheapflights users on 3/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Booking.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 4/1812:27 pm
PDX
- TYS
1 stop24h 06m
Frontier
Sun 4/264:28 pm
TYS
- PDX
1 stop21h 35m
Frontier
Deal found 3/13![Frontier logo]()
$368
This American Airlines deal was found by Cheapflights users on 3/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 4/2712:59 am
PDX
- TYS
1 stop8h 31m
American Airlines
Sat 5/22:06 pm
TYS
- PDX
1 stop9h 57m
American Airlines
Deal found 3/10![American Airlines logo]()
$372
One-way flights from Portland to KnoxvilleSearch for one-way flight options from Portland to Knoxville. Find affordable one-way fares based on user searches. Data last updated March 15, 2026.
Search for one-way flight options from Portland to Knoxville. Find affordable one-way fares based on user searches. Data last updated March 15, 2026.
This Booking.com deal was found by Cheapflights users on 3/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Booking.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 4/1812:27 pm
PDX
- TYS
1 stop24h 06m
Frontier
Deal found 3/14![Frontier logo]()
$116
This Kiwi.com deal was found by Cheapflights users on 3/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 4/2912:38 pm
PDX
- TYS
3 stops30h 55m
Multiple Airlines
Deal found 3/10![Multiple Airlines logo]()
$168
This American Airlines deal was found by Cheapflights users on 3/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 4/2911:40 pm
PDX
- TYS
1 stop9h 50m
American Airlines
Deal found 3/10![American Airlines logo]()
$180
This Delta deal was found by Cheapflights users on 3/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 5/121:43 pm
PDX
- TYS
1 stop6h 14m
Delta
Deal found 3/13![Delta logo]()
$190
This American Airlines deal was found by Cheapflights users on 3/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 4/69:44 pm
PDX
- TYS
1 stop9h 13m
American Airlines
Deal found 3/10![American Airlines logo]()
$193
This Kiwi.com deal was found by Cheapflights users on 3/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 3/2712:52 pm
PDX
- TYS
2 stops28h 53m
Multiple Airlines
Deal found 3/11![Multiple Airlines logo]()
$195
This American Airlines deal was found by Cheapflights users on 3/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 4/1811:48 am
PDX
- TYS
2 stops9h 08m
American Airlines
Deal found 3/14![American Airlines logo]()
$199
This Delta deal was found by Cheapflights users on 3/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 4/2112:30 am
PDX
- TYS
2 stops13h 12m
Delta
Deal found 3/10![Delta logo]()
$208
Find flight deals from Portland to Knoxville
Discover tips and strategies to find the most affordable flight options for your journey from Portland (PDX) to Knoxville (TYS). Learn about various techniques such as flexible date searches, comparing prices across and setting up price alerts. Use these methods to find the cheapest flights available for your travel needs. Data last updated March 15, 2026.
Most accurate provider | FlightHub 3 stars |
|---|---|
Most trusted provider | FlightHub 3 stars |
Round-trip from | $302 (Booking.com) |
One-way from | $116 (Booking.com) |
Popular in | March |
Cheapest in | August |
Average price | $582 |
Cheapflights Fare Finder
Customize your flight search to find flights from Portland to Knoxville that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated March 15, 2026.
Use the filters below to find and compare flights from Portland to Knoxville that are best for you.
Fly from
Fly to
Route
Depart
Return
Cheapest round-trip
PortlandKnoxville
PDX - TYS
PDXTYS
Portland
Mon 4/13
6:05 pm-9:22 am
2 stops12h 17m
Knoxville McGhee Tyson
Wed 4/15
5:26 pm-11:56 pm
2 stops9h 30m
$426
PortlandKnoxville
PDX - TYS
PDXTYS
Portland
Tue 7/21
11:40 pm-9:33 am
1 stop6h 53m
Knoxville McGhee Tyson
Tue 7/28
8:20 am-3:13 pm
2 stops9h 53m
$462
PortlandKnoxville
PDX - TYS
PDXTYS
Portland
Wed 9/9
11:39 am-10:56 pm
1 stop8h 17m
Knoxville McGhee Tyson
Sat 9/19
4:00 pm-11:41 pm
2 stops10h 41m
$462
PortlandKnoxville
PDX - TYS
PDXTYS
Portland
Tue 4/14
8:05 am-7:42 pm
1 stop8h 37m
Knoxville McGhee Tyson
Sat 4/18
8:30 am-6:08 pm
2 stops12h 38m
$477
Quickest round-trip
PortlandKnoxville
PDX - TYS
PDXTYS
Portland
Fri 7/31
9:45 pm-9:11 am
1 stop8h 26m
Knoxville McGhee Tyson
Thu 8/6
5:15 pm-9:46 pm
1 stop7h 31m
$477
PortlandKnoxville
PDX - TYS
PDXTYS
Portland
Tue 6/9
11:16 am-12:30 am
2 stops10h 14m
Knoxville McGhee Tyson
Mon 6/15
5:57 pm-11:53 pm
1 stop8h 56m
$487
PortlandKnoxville
PDX - TYS
PDXTYS
Portland
Tue 6/9
2:12 pm-12:30 am
1 stop7h 18m
Knoxville McGhee Tyson
Tue 6/23
5:45 am-3:56 pm
2 stops13h 11m
$513
PortlandKnoxville
PDX - TYS
PDXTYS
Portland
Sun 5/10
11:02 pm-10:21 am
1 stop8h 19m
Knoxville McGhee Tyson
Wed 5/20
1:57 pm-9:52 pm
2 stops10h 55m
$513
Cheapest one-way
PortlandKnoxville
PDX - TYS
PDXTYS
Portland
Sat 4/18
12:27 pm-3:33 pm
1 stop24h 06m
$116
PortlandKnoxville
PDX - TYS
PDXTYS
Portland
Wed 4/29
12:38 pm-10:33 pm
2 stops30h 55m
$188
Showing 1-10 of 19 resultsSorted by cheapest first
Compare providers for flights from Portland to Knoxville
Provider information is updated monthly. Please note that these providers often have deals for this flight, but the availability may vary on a day-by-day basis on Cheapflights.
Use the table below to compare price accuracy, trust ratings, and cancellation policies for each provider offering flight deals from Portland to Knoxville in March.
| Provider | Price Accuracy | Trust Score* |
|---|---|---|
| Price Accuracy1 star | Trust Score*3 stars | |
| Price Accuracy3 stars | Trust Score*3 stars |
- Most accurate provider: When it comes to deals on Portland-Knoxville flights, users find the pricing of FlightHub to be most consistent on Cheapflights vs. FlightHub Users can find the same prices on Portland-Knoxville flight deals on Cheapflights vs. FlightHub >95% of the time. Price accuracy is based on data collected from Portland-Knoxville flight searches over the past month and is updated monthly.
- Most trusted provider: When it comes to deals on Portland-Knoxville flights, Cheapflights users trust FlightHub the most. FlightHub has received a user feedback score of 3 out of 3 stars (3 being the best), meaning they have been trusted the most by Cheapflights users looking for Portland-Knoxville flight deals. Provider user feedback score is based on Cheapflights searches over the past month and is updated monthly.
Best time to book a flight from Portland to Knoxville
Have a flexible travel schedule? Discover the best time to fly to Knoxville from Portland with our price prediction graph.
PDX-TYS
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.
Cheapflights Insights
Everything you need to know about your flight from Portland to Knoxville
How far ahead should I book a flight from Portland to Knoxville?
Use this chart to determine the optimal time to book a round-trip flight from Portland to Knoxville. Price data was last updated on March 13, 2026.
The best time to book flights from Portland to Knoxville is 75 days before your desired departure date. The cost of your flight will likely increase significantly if you book two weeks in advance of your flight.
What is the cheapest month to book a flight from Portland to Knoxville?
Currently, July is the cheapest month in which you can book a flight from Portland to Knoxville (average of $126). Flying from Portland to Knoxville in May is currently the most expensive (average of $286). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.
Reviews of airlines servicing Knoxville
Get insights into the airlines that provide service to Knoxville. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Knoxville. Reviews last updated March 15, 2026.
Read through reviews of airlines operating flights from Portland to Knoxville, such as Delta,United Airlines, andAmerican Airlines. Reviews also offer insight into each airline's entertainment options, comfort, food, crew/service, and boarding process.
Overall
7.9
Crew
8.5
Comfort
7.9
Food
7.2
Entertainment
7.8
Boarding
8.1
Reviews
1 / 20
6.0
GoodJim,Nov 2025
AVL - ATL
Overall
7.9
Crew
8.5
Comfort
7.9
Food
7.2
Entertainment
7.8
Boarding
8.1
Reviews
1 / 20
6.0
GoodJim,Nov 2025
AVL - ATL
Overall
7.9
Crew
8.5
Comfort
7.9
Food
7.2
Entertainment
7.8
Boarding
8.1
Reviews
1 / 20
6.0
GoodJim,Nov 2025
AVL - ATL
Overall
7.9
Crew
8.5
Comfort
7.9
Food
7.2
Entertainment
7.8
Boarding
8.1
Reviews
1 / 20
6.0
GoodJim,Nov 2025
AVL - ATL
Overall
7.9
Crew
8.5
Comfort
7.9
Food
7.2
Entertainment
7.8
Boarding
8.1
Reviews
1 / 20
6.0
GoodJim,Nov 2025
AVL - ATL
Related info for your journey
Find useful and relevant information for your journey from Portland to Knoxville. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.
Traveling to a place near Knoxville?
Book flights to Knoxville if you plan to visit one of these locationsCherokee
Crossville
Corbin
Morristown
Bryson City
Alcoa
Murphy
Oak Ridge
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Find flights from Portland to Knoxville, based on your preferred cabin class, be it economy, premium economy, business, or first class.
Other flights to Knoxville
Explore flights to Knoxville departing from other origins. Flights are based on user searches made on Cheapflights and were last updated on March 15, 2026.
Portland and Knoxville flights
Browse other Portland and Knoxville flight options. Last updated on March 15, 2026.
Other flights from Portland
Browse through other flights departing from Portland. Flights are based on user searches made on Cheapflights and were last updated on March 15, 2026.
Popular flight searches
Check out other popular destinations found by fellow travelers in 2026
Top 4 airlines flying from Portland to Knoxville
Discover the top 4 airlines that operate flights from Portland to Knoxville. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated March 15, 2026.
| Airline | Cheapest | Average | Flexibility | On-time |
|---|---|---|---|---|
| Cheapest$240 | Average$326 | FlexibilityNo cancel fee | On-time62% | |
| Cheapest$248 | Average$462 | FlexibilityNo cancel fee | On-time69% | |
| Cheapest$256 | Average$428 | FlexibilityNo cancel fee | On-timeN/A | |
| Cheapest$298 | Average$448 | FlexibilityNo cancel fee | On-time71% |