$178+ Cheap flights from Portland to Knoxville (PDX - TYS)
This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 8/12. Fares are subject to change and may not be available on all flights or dates of travel.
PDX — TYS
Aug 18 — Aug 251
Round-trip
1 adult, Economy
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Find cheap flights from Portland to Knoxville with Cheapflights
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Enter your travel information like dates, passengers, trip type (one-way or round trip), and preferred cabin class then click “Find deals”2. Select your favorite providers
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Review each provider’s pricing and select the best option for you! Book through your favorite provider’s website for a seamless experience.Cheap flight deals from Portland to Knoxville
Cheapest
Best
Last-minute
One-way
Cheapest flights from Portland to KnoxvilleExplore the most affordable flight options available from Portland to Knoxville. Find the lowest fares from popular airlines and budget airlines, with prices last updated on July 19, 2026.
Explore the most affordable flight options available from Portland to Knoxville. Find the lowest fares from popular airlines and budget airlines, with prices last updated on July 19, 2026.
This Kiwi.com deal was found by Cheapflights users on 7/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 10/215:35 pm
PDX
- TYS
1 stop16h 36m
Multiple Airlines
Sun 10/256:30 am
TYS
- PDX
1 stop13h 05m
Multiple Airlines
Deal found 7/18![Multiple Airlines logo]()
$313
This Kiwi.com deal was found by Cheapflights users on 7/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 9/45:56 pm
PDX
- TYS
2 stops22h 57m
Multiple Airlines
Sun 9/67:00 am
TYS
- PDX
1 stop13h 11m
Multiple Airlines
Deal found 7/16![Multiple Airlines logo]()
$321
This American Airlines deal was found by Cheapflights users on 7/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 9/126:00 am
PDX
- TYS
1 stop7h 42m
American Airlines
Tue 9/225:35 pm
TYS
- PDX
1 stop8h 48m
American Airlines
Deal found 7/15![American Airlines logo]()
$355
This Southwest deal was found by Cheapflights users on 7/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 8/1310:45 pm
PDX
- TYS
2 stops10h 35m
Southwest
Thu 8/204:50 pm
TYS
- PDX
1 stop7h 25m
Southwest
Deal found 7/16![Southwest logo]()
$360
This Southwest deal was found by Cheapflights users on 7/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 8/1310:45 pm
PDX
- TYS
2 stops10h 35m
Southwest
Tue 8/251:55 pm
TYS
- PDX
2 stops11h 20m
Southwest
Deal found 7/14![Southwest logo]()
$366
This American Airlines deal was found by Cheapflights users on 7/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 8/49:47 pm
PDX
- TYS
1 stop8h 56m
American Airlines
Tue 8/116:03 am
TYS
- PDX
1 stop7h 51m
American Airlines
Deal found 7/14![American Airlines logo]()
$368
This American Airlines deal was found by Cheapflights users on 7/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 8/2211:34 pm
PDX
- TYS
1 stop8h 32m
American Airlines
Sat 8/296:03 am
TYS
- PDX
1 stop9h 45m
American Airlines
Deal found 7/15![American Airlines logo]()
$370
This Southwest deal was found by Cheapflights users on 7/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 8/67:00 pm
PDX
- TYS
2 stops15h 25m
Southwest
Thu 8/134:50 pm
TYS
- PDX
2 stops9h 25m
Southwest
Deal found 7/16![Southwest logo]()
$371
This American Airlines deal was found by Cheapflights users on 7/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 9/306:00 am
PDX
- TYS
1 stop7h 42m
American Airlines
Tue 10/612:41 pm
TYS
- PDX
2 stops10h 00m
American Airlines
Deal found 7/14![American Airlines logo]()
$375
This Kiwi.com deal was found by Cheapflights users on 7/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 9/243:22 pm
PDX
- TYS
2 stops18h 19m
Multiple Airlines
Sun 9/277:00 am
TYS
- PDX
1 stop12h 35m
Multiple Airlines
Deal found 7/18![Multiple Airlines logo]()
$376
Best flights from Portland to KnoxvilleDiscover carefully curated flight deals from Portland to Knoxville that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated July 19, 2026.
Discover carefully curated flight deals from Portland to Knoxville that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated July 19, 2026.
This Southwest deal was found by Cheapflights users on 7/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 8/67:00 pm
PDX
- TYS
2 stops15h 25m
Southwest
Thu 8/134:50 pm
TYS
- PDX
2 stops9h 25m
Southwest
Deal found 7/16![Southwest logo]()
$371
This United Airlines deal was found by Cheapflights users on 7/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 9/127:02 am
PDX
- TYS
1 stop6h 56m
United Airlines
Tue 9/221:10 pm
TYS
- PDX
1 stop10h 00m
United Airlines
Deal found 7/17![United Airlines logo]()
$384
This United Airlines deal was found by Cheapflights users on 7/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/211:30 pm
PDX
- TYS
1 stop7h 15m
United Airlines
Sat 10/106:00 am
TYS
- PDX
1 stop8h 33m
United Airlines
Deal found 7/14![United Airlines logo]()
$406
This Southwest deal was found by Cheapflights users on 7/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 9/305:50 am
PDX
- TYS
2 stops10h 05m
Southwest
Tue 10/67:15 am
TYS
- PDX
2 stops11h 05m
Southwest
Deal found 7/14![Southwest logo]()
$417
This United Airlines deal was found by Cheapflights users on 7/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 10/38:30 am
PDX
- TYS
1 stop9h 30m
United Airlines
Sat 10/106:00 am
TYS
- PDX
1 stop8h 33m
United Airlines
Deal found 7/15![United Airlines logo]()
$465
This Southwest deal was found by Cheapflights users on 7/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/27:40 am
PDX
- TYS
2 stops12h 00m
Southwest
Sat 10/105:25 pm
TYS
- PDX
1 stop7h 00m
Southwest
Deal found 7/14![Southwest logo]()
$468
This United Airlines deal was found by Cheapflights users on 7/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 8/2511:02 pm
PDX
- TYS
1 stop7h 55m
United Airlines
Sat 8/297:15 am
TYS
- PDX
2 stops10h 50m
United Airlines
Deal found 7/14![United Airlines logo]()
$470
This Southwest deal was found by Cheapflights users on 7/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/155:00 am
PDX
- TYS
2 stops14h 40m
Southwest
Mon 10/191:50 pm
TYS
- PDX
2 stops9h 55m
Southwest
Deal found 7/16![Southwest logo]()
$524
Last-minute flights from Portland to KnoxvilleDiscover last-minute flight deals from Portland to Knoxville. Data last updated July 19, 2026 and is based on user searches.
Discover last-minute flight deals from Portland to Knoxville. Data last updated July 19, 2026 and is based on user searches.
This American Airlines deal was found by Cheapflights users on 7/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 8/49:47 pm
PDX
- TYS
1 stop8h 56m
American Airlines
Tue 8/116:03 am
TYS
- PDX
1 stop7h 51m
American Airlines
Deal found 7/14![American Airlines logo]()
$368
This Southwest deal was found by Cheapflights users on 7/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 8/67:00 pm
PDX
- TYS
2 stops15h 25m
Southwest
Thu 8/134:50 pm
TYS
- PDX
2 stops9h 25m
Southwest
Deal found 7/16![Southwest logo]()
$371
This United Airlines deal was found by Cheapflights users on 7/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 8/611:30 pm
PDX
- TYS
1 stop8h 12m
United Airlines
Thu 8/136:02 pm
TYS
- PDX
1 stop7h 50m
United Airlines
Deal found 7/16![United Airlines logo]()
$382
This American Airlines deal was found by Cheapflights users on 7/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 8/1111:34 pm
PDX
- TYS
1 stop8h 36m
American Airlines
Sat 8/156:52 pm
TYS
- PDX
1 stop8h 07m
American Airlines
Deal found 7/16![American Airlines logo]()
$390
This Southwest deal was found by Cheapflights users on 7/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 8/1310:45 pm
PDX
- TYS
2 stops10h 35m
Southwest
Thu 8/204:50 pm
TYS
- PDX
1 stop7h 25m
Southwest
Deal found 7/16![Southwest logo]()
$360
This Southwest deal was found by Cheapflights users on 7/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 8/1310:45 pm
PDX
- TYS
2 stops10h 35m
Southwest
Tue 8/251:55 pm
TYS
- PDX
2 stops11h 20m
Southwest
Deal found 7/14![Southwest logo]()
$366
This United Airlines deal was found by Cheapflights users on 7/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 8/138:15 am
PDX
- TYS
1 stop9h 38m
United Airlines
Tue 8/254:50 pm
TYS
- PDX
1 stop7h 15m
United Airlines
Deal found 7/14![United Airlines logo]()
$385
This United Airlines deal was found by Cheapflights users on 7/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 8/227:16 am
PDX
- TYS
1 stop6h 42m
United Airlines
Sat 8/297:00 am
TYS
- PDX
1 stop7h 28m
United Airlines
Deal found 7/14![United Airlines logo]()
$355
This American Airlines deal was found by Cheapflights users on 7/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 8/2211:34 pm
PDX
- TYS
1 stop8h 32m
American Airlines
Sat 8/296:03 am
TYS
- PDX
1 stop9h 45m
American Airlines
Deal found 7/15![American Airlines logo]()
$370
One-way flights from Portland to KnoxvilleSearch for one-way flight options from Portland to Knoxville. Find affordable one-way fares based on user searches. Data last updated July 19, 2026.
Search for one-way flight options from Portland to Knoxville. Find affordable one-way fares based on user searches. Data last updated July 19, 2026.
This United Airlines deal was found by Cheapflights users on 7/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 8/125:00 am
PDX
- TYS
1 stop7h 54m
United Airlines
Deal found 7/15![United Airlines logo]()
$178
This Kiwi.com deal was found by Cheapflights users on 7/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 8/145:49 pm
PDX
- TYS
2 stops25h 14m
Multiple Airlines
Deal found 7/15![Multiple Airlines logo]()
$181
This Southwest deal was found by Cheapflights users on 7/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 8/125:50 am
PDX
- TYS
2 stops10h 05m
Southwest
Deal found 7/15![Southwest logo]()
$183
This Kiwi.com deal was found by Cheapflights users on 7/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 9/253:22 pm
PDX
- TYS
3 stops46h 26m
Multiple Airlines
Deal found 7/18![Multiple Airlines logo]()
$186
This Kiwi.com deal was found by Cheapflights users on 7/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 7/295:21 pm
PDX
- TYS
2 stops26h 03m
Multiple Airlines
Deal found 7/19![Multiple Airlines logo]()
$193
This United Airlines deal was found by Cheapflights users on 7/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 9/2411:30 pm
PDX
- TYS
1 stop7h 15m
United Airlines
Deal found 7/15![United Airlines logo]()
$202
This Southwest deal was found by Cheapflights users on 7/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 9/2811:30 pm
PDX
- TYS
2 stops9h 35m
Southwest
Deal found 7/18![Southwest logo]()
$212
This Kiwi.com deal was found by Cheapflights users on 7/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 9/283:22 pm
PDX
- TYS
3 stops39h 43m
Multiple Airlines
Deal found 7/18![Multiple Airlines logo]()
$226
This American Airlines deal was found by Cheapflights users on 7/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 9/2511:08 pm
PDX
- TYS
1 stop8h 42m
American Airlines
Deal found 7/15![American Airlines logo]()
$229
Find flight deals from Portland to Knoxville
Discover tips and strategies to find the most affordable flight options for your journey from Portland (PDX) to Knoxville (TYS). Learn about various techniques such as flexible date searches, comparing prices across and setting up price alerts. Use these methods to find the cheapest flights available for your travel needs. Data last updated July 19, 2026.
Most accurate provider | FlightHub 3 stars |
|---|---|
Most trusted provider | FlightHub 3 stars |
Round-trip from | $309 (Kiwi.com) |
One-way from | $178 (United Airlines) |
Popular in | May |
Cheapest in | August |
Average price | $585 |
Cheapflights Fare Finder
Customize your flight search to find flights from Portland to Knoxville that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated July 19, 2026.
Use the filters below to find and compare flights from Portland to Knoxville that are best for you.
Fly from
Fly to
Route
Depart
Return
Cheapest round-trip
PortlandKnoxville
PDX - TYS
PDXTYS
Portland
Thu 8/6
7:00 pm-1:25 pm
2 stops15h 25m
Knoxville McGhee Tyson
Thu 8/13
4:50 pm-11:15 pm
2 stops9h 25m
$371
PortlandKnoxville
PDX - TYS
PDXTYS
Portland
Sat 9/12
7:02 am-4:58 pm
1 stop6h 56m
Knoxville McGhee Tyson
Tue 9/22
1:10 pm-8:10 pm
1 stop10h 00m
$384
Quickest round-trip
PortlandKnoxville
PDX - TYS
PDXTYS
Portland
Fri 10/2
11:30 pm-9:45 am
1 stop7h 15m
Knoxville McGhee Tyson
Sat 10/10
6:00 am-11:33 am
1 stop8h 33m
$406
PortlandKnoxville
PDX - TYS
PDXTYS
Portland
Wed 9/30
5:50 am-6:55 pm
2 stops10h 05m
Knoxville McGhee Tyson
Tue 10/6
7:15 am-3:20 pm
2 stops11h 05m
$417
PortlandKnoxville
PDX - TYS
PDXTYS
Portland
Sat 10/3
8:30 am-9:00 pm
1 stop9h 30m
Knoxville McGhee Tyson
Sat 10/10
6:00 am-11:33 am
1 stop8h 33m
$465
PortlandKnoxville
PDX - TYS
PDXTYS
Portland
Fri 10/2
7:40 am-10:40 pm
2 stops12h 00m
Knoxville McGhee Tyson
Sat 10/10
5:25 pm-9:25 pm
1 stop7h 00m
$468
PortlandKnoxville
PDX - TYS
PDXTYS
Portland
Tue 8/25
11:02 pm-9:57 am
1 stop7h 55m
Knoxville McGhee Tyson
Sat 8/29
7:15 am-3:05 pm
2 stops10h 50m
$470
PortlandKnoxville
PDX - TYS
PDXTYS
Portland
Thu 10/15
5:00 am-10:40 pm
2 stops14h 40m
Knoxville McGhee Tyson
Mon 10/19
1:50 pm-8:45 pm
2 stops9h 55m
$524
Cheapest one-way
PortlandKnoxville
PDX - TYS
PDXTYS
Portland
Wed 8/12
5:00 am-3:54 pm
1 stop7h 54m
$178
PortlandKnoxville
PDX - TYS
PDXTYS
Portland
Wed 8/12
5:50 am-6:55 pm
2 stops10h 05m
$183
Showing 1-10 of 20 resultsSorted by cheapest first
Compare providers for flights from Portland to Knoxville
Provider information is updated monthly. Please note that these providers often have deals for this flight, but the availability may vary on a day-by-day basis on Cheapflights.
Use the table below to compare price accuracy, trust ratings, and cancellation policies for each provider offering flight deals from Portland to Knoxville in July.
| Provider | Price Accuracy | Trust Score* |
|---|---|---|
| Price Accuracy1 star | Trust Score*3 stars | |
| Price Accuracy3 stars | Trust Score*3 stars |
- Most accurate provider: When it comes to deals on Portland-Knoxville flights, users find the pricing of FlightHub to be most consistent on Cheapflights vs. FlightHub Users can find the same prices on Portland-Knoxville flight deals on Cheapflights vs. FlightHub >95% of the time. Price accuracy is based on data collected from Portland-Knoxville flight searches over the past month and is updated monthly.
- Most trusted provider: When it comes to deals on Portland-Knoxville flights, Cheapflights users trust FlightHub the most. FlightHub has received a user feedback score of 3 out of 3 stars (3 being the best), meaning they have been trusted the most by Cheapflights users looking for Portland-Knoxville flight deals. Provider user feedback score is based on Cheapflights searches over the past month and is updated monthly.
Best time to book a flight from Portland to Knoxville
Have a flexible travel schedule? Discover the best time to fly to Knoxville from Portland with our price prediction graph.
PDX-TYS
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.
Cheapflights Insights
Everything you need to know about your flight from Portland to Knoxville
How far ahead should I book a flight from Portland to Knoxville?
The best time to book flights from Portland to Knoxville is 38 days before your desired departure date. The cost of your flight will likely increase significantly if you book two weeks in advance of your flight.
What is the cheapest month to book a flight from Portland to Knoxville?
Currently, August is the cheapest month in which you can book a flight from Portland to Knoxville (average of $412). Flying from Portland to Knoxville in May is currently the most expensive (average of $611). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.
How much does it cost to fly round-trip from Portland to Knoxville?
Reviews of airlines servicing Knoxville
Get insights into the airlines that provide service to Knoxville. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Knoxville. Reviews last updated July 19, 2026.
Read through reviews of airlines operating flights from Portland to Knoxville, such as Delta,United Airlines, andAmerican Airlines. Reviews also offer insight into each airline's entertainment options, comfort, food, crew/service, and boarding process.
Crew
8.5
Overall
7.8
Food
7.2
Entertainment
7.8
Boarding
8.1
Comfort
7.8
Reviews
1 / 20
10.0
ExcellentAnonymous,May 2026
SEA - KOA
Crew
8.5
Overall
7.8
Food
7.2
Entertainment
7.8
Boarding
8.1
Comfort
7.8
Reviews
1 / 20
10.0
ExcellentAnonymous,May 2026
SEA - KOA
Crew
8.5
Overall
7.8
Food
7.2
Entertainment
7.8
Boarding
8.1
Comfort
7.8
Reviews
1 / 20
10.0
ExcellentAnonymous,May 2026
SEA - KOA
Crew
8.5
Overall
7.8
Food
7.2
Entertainment
7.8
Boarding
8.1
Comfort
7.8
Reviews
1 / 20
10.0
ExcellentAnonymous,May 2026
SEA - KOA
Related info for your journey
Find useful and relevant information for your journey from Portland to Knoxville. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.
Traveling to a place near Knoxville?
Book flights to Knoxville if you plan to visit one of these locationsCherokee
Crossville
Morristown
Bryson City
Murphy
Alcoa
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Alternative routes for Portland to Knoxville
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Complete your trip
Complete your trip to Knoxville by adding a car rental and/or hotel reservation to your travel itinerary.
Search flights from Portland to Knoxville by cabin class
Find flights from Portland to Knoxville, based on your preferred cabin class, be it economy, premium economy, business, or first class.
Other flights to Knoxville
Explore flights to Knoxville departing from other origins. Flights are based on user searches made on Cheapflights and were last updated on July 19, 2026.
Portland and Knoxville flights
Browse other Portland and Knoxville flight options. Last updated on July 19, 2026.
Other flights from Portland
Browse through other flights departing from Portland. Flights are based on user searches made on Cheapflights and were last updated on July 19, 2026.
Popular flight searches
Check out other popular destinations found by fellow travelers in 2026
Top 3 airlines flying from Portland to Knoxville
Discover the top 3 airlines that operate flights from Portland to Knoxville. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated July 19, 2026.
| Airline | Cheapest | Average | Flexibility | On-time |
|---|---|---|---|---|
| Cheapest$268 | Average$498 | FlexibilityNo cancel fee | On-timeN/A | |
| Cheapest$304 | Average$472 | FlexibilityNo cancel fee | On-time71% | |
| Cheapest$328 | Average$536 | FlexibilityNo cancel fee | On-time69% |