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Knoxville

$147+ Cheap flights from Portland to Knoxville (PDX - TYS)

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 4/22. Fares are subject to change and may not be available on all flights or dates of travel.
PDX — TYS
Apr 29 — May 61
Wed 4/29
Wed 5/6
1 adult, Economy
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Cheap flight deals from Portland to Knoxville

Cheapest flights from Portland to Knoxville
Explore the most affordable flight options available from Portland to Knoxville. Find the lowest fares from popular airlines and budget airlines, with prices last updated on March 30, 2026.

This American Airlines deal was found by Cheapflights users on 3/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 4/221:52 pm
PDX
-
TYS
1 stop7h 04m
American Airlines
Wed 4/294:09 pm
TYS
-
PDX
1 stop9h 40m
American Airlines
Deal found 3/25$293
This American Airlines deal was found by Cheapflights users on 3/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 5/711:40 pm
PDX
-
TYS
1 stop9h 50m
American Airlines
Tue 5/125:06 pm
TYS
-
PDX
1 stop9h 50m
American Airlines
Deal found 3/25$344
This United Airlines deal was found by Cheapflights users on 3/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 4/2811:59 pm
PDX
-
TYS
1 stop7h 09m
United Airlines
Mon 5/46:01 pm
TYS
-
PDX
1 stop8h 54m
United Airlines
Deal found 3/25$349
This American Airlines deal was found by Cheapflights users on 3/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 5/3112:40 am
PDX
-
TYS
1 stop9h 22m
American Airlines
Thu 6/48:11 pm
TYS
-
PDX
1 stop7h 39m
American Airlines
Deal found 3/25$355
This American Airlines deal was found by Cheapflights users on 3/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 5/411:40 pm
PDX
-
TYS
1 stop9h 50m
American Airlines
Sat 5/93:58 pm
TYS
-
PDX
2 stops9h 49m
American Airlines
Deal found 3/26$371
This American Airlines deal was found by Cheapflights users on 3/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 5/285:10 am
PDX
-
TYS
1 stop8h 33m
American Airlines
Wed 6/36:20 pm
TYS
-
PDX
1 stop8h 32m
American Airlines
Deal found 3/26$372
This American Airlines deal was found by Cheapflights users on 3/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 4/2411:40 pm
PDX
-
TYS
1 stop9h 50m
American Airlines
Thu 4/306:54 pm
TYS
-
PDX
1 stop8h 00m
American Airlines
Deal found 3/26$385
This United Airlines deal was found by Cheapflights users on 3/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 4/257:00 am
PDX
-
TYS
1 stop9h 56m
United Airlines
Sat 5/24:20 pm
TYS
-
PDX
1 stop7h 49m
United Airlines
Deal found 3/28$387

Find flight deals from Portland to Knoxville

Discover tips and strategies to find the most affordable flight options for your journey from Portland (PDX) to Knoxville (TYS). Learn about various techniques such as flexible date searches, comparing prices across and setting up price alerts. Use these methods to find the cheapest flights available for your travel needs. Data last updated March 30, 2026.

Most accurate provider

FlightHub
3 stars

Most trusted provider

FlightHub
3 stars

Round-trip from

$293
(American Airlines)

One-way from

$147
(American Airlines)

Popular in

March

Cheapest in

August

Average price

$582
Provider with most accurate pricing for Portland-Knoxville McGhee Tyson flight deals.
Search Deals
Provider most trusted by Cheapflights users for Portland-Knoxville McGhee Tyson flights.
Search Deals
From Portland to Knoxville McGhee Tyson
Search Deals
One-way flight from Portland to Knoxville McGhee Tyson
Search Deals
Highest demand for flights based on searches. 1% potential increase in price ($8 potential increase over avg. RT price).
Search Deals
Cheapest flight prices on average. 3% potential price decrease ($13 potential savings vs. average RT price).
Search Deals
Average for round-trip flights in March 2026
Search Deals

Cheapflights Fare Finder

 
Customize your flight search to find flights from Portland to Knoxville that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated March 30, 2026.
Use the filters below to find and compare flights from Portland to Knoxville that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

Cheapest round-trip

PortlandKnoxville

PDX - TYS

PDXTYS

Portland

Wed 4/22

1:52 pm-11:56 pm

1 stop7h 04m

Knoxville McGhee Tyson

Wed 4/29

3:58 pm-10:56 pm

2 stops9h 58m

$334

PortlandKnoxville

PDX - TYS

PDXTYS

Portland

Tue 4/21

7:14 pm-10:08 am

2 stops11h 54m

Knoxville McGhee Tyson

Wed 4/22

5:15 pm-10:58 pm

1 stop8h 43m

$408

PortlandKnoxville

PDX - TYS

PDXTYS

Portland

Thu 5/28

10:40 pm-2:27 pm

2 stops12h 47m

Knoxville McGhee Tyson

Wed 6/3

5:57 pm-11:53 pm

1 stop8h 56m

$439

PortlandKnoxville

PDX - TYS

PDXTYS

Portland

Fri 4/24

10:50 am-10:34 pm

1 stop8h 44m

Knoxville McGhee Tyson

Tue 4/28

7:00 am-11:46 am

1 stop7h 46m

$452
Quickest round-trip

PortlandKnoxville

PDX - TYS

PDXTYS

Portland

Tue 7/7

2:25 pm-12:35 am

1 stop7h 10m

Knoxville McGhee Tyson

Sat 7/11

5:57 pm-12:02 am

1 stop9h 05m

$457

PortlandKnoxville

PDX - TYS

PDXTYS

Portland

Tue 6/9

10:40 pm-2:27 pm

2 stops12h 47m

Knoxville McGhee Tyson

Tue 6/23

6:30 am-11:38 am

1 stop8h 08m

$490

PortlandKnoxville

PDX - TYS

PDXTYS

Portland

Tue 4/21

10:50 pm-10:26 am

1 stop8h 36m

Knoxville McGhee Tyson

Wed 4/22

1:20 pm-8:02 pm

1 stop9h 42m

$491

PortlandKnoxville

PDX - TYS

PDXTYS

Portland

Fri 9/18

7:35 pm-11:55 am

2 stops13h 20m

Knoxville McGhee Tyson

Mon 9/21

8:25 am-3:00 pm

1 stop9h 35m

$508

PortlandKnoxville

PDX - TYS

PDXTYS

Portland

Mon 4/20

10:56 pm-3:09 pm

2 stops13h 13m

Knoxville McGhee Tyson

Sat 4/25

9:40 am-6:34 pm

2 stops11h 54m

$516
Cheapest one-way

PortlandKnoxville

PDX - TYS

PDXTYS

Portland

Wed 4/22

11:56 am-11:56 pm

1 stop9h 00m

$147

Flights are sorted by cheapest round-trip flights first.

Deals found on 3/26

Showing 1-10 of 17 resultsSorted by cheapest first
1
2

Compare providers for flights from Portland to Knoxville

Provider information is updated monthly. Please note that these providers often have deals for this flight, but the availability may vary on a day-by-day basis on Cheapflights.
Use the table below to compare price accuracy, trust ratings, and cancellation policies for each provider offering flight deals from Portland to Knoxville in March.
ProviderPrice AccuracyTrust Score*
ExpediaPrice Accuracy1 starTrust Score*3 stars
FlightHubPrice Accuracy3 starsTrust Score*3 stars

*The Trust Score is based on feedback from users after their booking experience. It measures overall satisfaction, helping us identify issues like hidden fees, problems during the ticketing process, and the quality of customer service. This score is our best indicator of the provider's quality and reliability.

  • Most accurate provider: When it comes to deals on Portland-Knoxville flights, users find the pricing of FlightHub to be most consistent on Cheapflights vs. FlightHub Users can find the same prices on Portland-Knoxville flight deals on Cheapflights vs. FlightHub >95% of the time. Price accuracy is based on data collected from Portland-Knoxville flight searches over the past month and is updated monthly.
  • Most trusted provider: When it comes to deals on Portland-Knoxville flights, Cheapflights users trust FlightHub the most. FlightHub has received a user feedback score of 3 out of 3 stars (3 being the best), meaning they have been trusted the most by Cheapflights users looking for Portland-Knoxville flight deals. Provider user feedback score is based on Cheapflights searches over the past month and is updated monthly.

Best time to book a flight from Portland to Knoxville

Have a flexible travel schedule? Discover the best time to fly to Knoxville from Portland with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Portland to Knoxville

How far ahead should I book a flight from Portland to Knoxville?

Use this chart to determine the optimal time to book a round-trip flight from Portland to Knoxville. Price data was last updated on March 13, 2026.

The best time to book flights from Portland to Knoxville is 75 days before your desired departure date. The cost of your flight will likely increase significantly if you book two weeks in advance of your flight.

What is the cheapest month to book a flight from Portland to Knoxville?

Currently, July is the cheapest month in which you can book a flight from Portland to Knoxville (average of $126). Flying from Portland to Knoxville in May is currently the most expensive (average of $286). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

How much does it cost to fly round-trip from Portland to Knoxville?

Reviews of airlines servicing Knoxville

Get insights into the airlines that provide service to Knoxville. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Knoxville. Reviews last updated March 30, 2026.
Read through reviews of airlines operating flights from Portland to Knoxville, such as Delta,United Airlines, andAmerican Airlines. Reviews also offer insight into each airline's entertainment options, comfort, food, crew/service, and boarding process.
Delta
7.9
Good
8,358 reviews

Overall

7.9

Crew

8.5

Boarding

8.1

Comfort

7.9

Food

7.2

Entertainment

7.8

Reviews

1 / 20
6.0
Good

Jim,Nov 2025

AVL - ATL

The exit row seats without a seat in front are great for leg room but don’t have a fold out entertainment console so you’re forced to use the screen several feet in front of you (there is, at least, a remote). Best to bring a tablet loaded with entertainment or a book.
Delta
7.9
Good
8,358 reviews
Delta
7.9
Good
8,358 reviews

Overall

7.9

Crew

8.5

Boarding

8.1

Comfort

7.9

Food

7.2

Entertainment

7.8

Reviews

1 / 20
6.0
Good

Jim,Nov 2025

AVL - ATL

The exit row seats without a seat in front are great for leg room but don’t have a fold out entertainment console so you’re forced to use the screen several feet in front of you (there is, at least, a remote). Best to bring a tablet loaded with entertainment or a book.
United Airlines
7.4
Good
9,514 reviews
Delta
7.9
Good
8,358 reviews

Overall

7.9

Crew

8.5

Boarding

8.1

Comfort

7.9

Food

7.2

Entertainment

7.8

Reviews

1 / 20
6.0
Good

Jim,Nov 2025

AVL - ATL

The exit row seats without a seat in front are great for leg room but don’t have a fold out entertainment console so you’re forced to use the screen several feet in front of you (there is, at least, a remote). Best to bring a tablet loaded with entertainment or a book.
American Airlines
7.1
Good
11,531 reviews
Delta
7.9
Good
8,358 reviews

Overall

7.9

Crew

8.5

Boarding

8.1

Comfort

7.9

Food

7.2

Entertainment

7.8

Reviews

1 / 20
6.0
Good

Jim,Nov 2025

AVL - ATL

The exit row seats without a seat in front are great for leg room but don’t have a fold out entertainment console so you’re forced to use the screen several feet in front of you (there is, at least, a remote). Best to bring a tablet loaded with entertainment or a book.
Frontier
5.7
Fair
3,010 reviews
Delta
7.9
Good
8,358 reviews

Overall

7.9

Crew

8.5

Boarding

8.1

Comfort

7.9

Food

7.2

Entertainment

7.8

Reviews

1 / 20
6.0
Good

Jim,Nov 2025

AVL - ATL

The exit row seats without a seat in front are great for leg room but don’t have a fold out entertainment console so you’re forced to use the screen several feet in front of you (there is, at least, a remote). Best to bring a tablet loaded with entertainment or a book.

Related info for your journey

Find useful and relevant information for your journey from Portland to Knoxville. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • How long is the flight from Portland to Knoxville?

    For as low as $334, American Airlines can have you in Knoxville from Portland in 7h 04m. There are 2107 mi between Portland and Knoxville. This flight may include one or multiple stops.

  • What are the cheapest airlines flying from Portland to Knoxville round-trip?

    Cheapflights users have booked flights from Portland to Knoxville round-trip from $240. Other airlines that can offer you cheap pricing are Delta, from $256, and United Airlines, from $279. Frontier is 46% cheaper than the average price of flights available within the next 90 days to this destination.

  • What are the cheapest airlines to fly from Portland to Knoxville one-way?

    The cheapest airline one-way is Frontier, with whom users have recently found tickets for as low as $107. However, be on the lookout for offers from American Airlines and Delta, as they are both options that can get you from Portland to Knoxville for a low price.

  • Can I find deals for flights from Portland to Knoxville that include hotel bookings?

    Yes. In addition to deals on Portland to Knoxville flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Portland to Knoxville?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Portland to Knoxville.

  • Can I find deals for business class flights from Portland to Knoxville?

    Yes. Cheapflights offers flight deals from Portland to Knoxville by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Portland to Knoxville?

    Currently, July is the cheapest month in which you can book a flight from Portland to Knoxville (average of $126). Flying from Portland to Knoxville in May is currently the most expensive (average of $286). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

Traveling to a place near Knoxville?

Book flights to Knoxville if you plan to visit one of these locations
Cherokee
Crossville
Corbin
Morristown
Bryson City
Alcoa
Murphy
Oak Ridge

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Top 4 airlines flying from Portland to Knoxville

Discover the top 4 airlines that operate flights from Portland to Knoxville. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated March 30, 2026.
AirlineCheapestAverageFlexibilityOn-time
DeltaCheapest$256Average$428FlexibilityNo cancel feeOn-timeN/A
FrontierCheapest$264Average$343FlexibilityNo cancel feeOn-time62%
United AirlinesCheapest$279Average$498FlexibilityNo cancel feeOn-time69%
American AirlinesCheapest$298Average$449FlexibilityNo cancel feeOn-time71%

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