$147+ Cheap flights from Portland to Knoxville (PDX - TYS)
This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 8/6. Fares are subject to change and may not be available on all flights or dates of travel.
PDX — TYS
Aug 8 — Aug 151
Round-trip
1 adult, Economy
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Find cheap flights from Portland to Knoxville with Cheapflights
1. Tell us where you want to go
Enter your travel information like dates, passengers, trip type (one-way or round trip), and preferred cabin class then click “Find deals”2. Select your favorite providers
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Review each provider’s pricing and select the best option for you! Book through your favorite provider’s website for a seamless experience.Cheap flight deals from Portland to Knoxville
Cheapest
Best
Last-minute
One-way
Cheapest flights from Portland to KnoxvilleExplore the most affordable flight options available from Portland to Knoxville. Find the lowest fares from popular airlines and budget airlines, with prices last updated on July 9, 2026.
Explore the most affordable flight options available from Portland to Knoxville. Find the lowest fares from popular airlines and budget airlines, with prices last updated on July 9, 2026.
This Kiwi.com deal was found by Cheapflights users on 7/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 10/33:22 pm
PDX
- TYS
1 stop18h 49m
Multiple Airlines
Thu 10/86:30 am
TYS
- PDX
1 stop13h 05m
Multiple Airlines
Deal found 7/8![Multiple Airlines logo]()
$287
This Delta deal was found by Cheapflights users on 7/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 10/51:35 pm
PDX
- TYS
1 stop6h 39m
Delta
Thu 10/86:57 pm
TYS
- PDX
1 stop7h 46m
Delta
Deal found 7/8![Delta logo]()
$293
This Kiwi.com deal was found by Cheapflights users on 7/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 10/33:22 pm
PDX
- TYS
1 stop18h 49m
Multiple Airlines
Mon 10/122:47 pm
TYS
- PDX
1 stop8h 52m
Multiple Airlines
Deal found 7/8![Multiple Airlines logo]()
$295
This American Airlines deal was found by Cheapflights users on 7/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 9/126:00 am
PDX
- TYS
1 stop7h 42m
American Airlines
Tue 9/225:35 pm
TYS
- PDX
1 stop8h 48m
American Airlines
Deal found 7/9![American Airlines logo]()
$297
This Kiwi.com deal was found by Cheapflights users on 7/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 10/33:22 pm
PDX
- TYS
1 stop18h 49m
Multiple Airlines
Sun 10/116:30 am
TYS
- PDX
1 stop13h 05m
Multiple Airlines
Deal found 7/8![Multiple Airlines logo]()
$308
This Kiwi.com deal was found by Cheapflights users on 7/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 10/33:22 pm
PDX
- TYS
1 stop18h 49m
Multiple Airlines
Wed 10/710:28 am
TYS
- PDX
2 stops28h 11m
Multiple Airlines
Deal found 7/8![Multiple Airlines logo]()
$317
This American Airlines deal was found by Cheapflights users on 7/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 8/312:45 am
PDX
- TYS
1 stop9h 08m
American Airlines
Tue 8/116:03 am
TYS
- PDX
1 stop7h 51m
American Airlines
Deal found 7/8![American Airlines logo]()
$323
This Kiwi.com deal was found by Cheapflights users on 7/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 7/295:21 pm
PDX
- TYS
1 stop17h 30m
Multiple Airlines
Wed 8/128:19 pm
TYS
- PDX
1 stop23h 32m
Multiple Airlines
Deal found 7/8![Multiple Airlines logo]()
$329
Best flights from Portland to KnoxvilleDiscover carefully curated flight deals from Portland to Knoxville that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated July 9, 2026.
Discover carefully curated flight deals from Portland to Knoxville that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated July 9, 2026.
This Delta deal was found by Cheapflights users on 7/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 10/410:57 pm
PDX
- TYS
1 stop9h 21m
Delta
Thu 10/86:57 pm
TYS
- PDX
1 stop7h 46m
Delta
Deal found 7/8![Delta logo]()
$375
This United Airlines deal was found by Cheapflights users on 7/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 9/210:35 am
PDX
- TYS
1 stop7h 18m
United Airlines
Sat 9/56:02 pm
TYS
- PDX
1 stop7h 48m
United Airlines
Deal found 7/8![United Airlines logo]()
$403
This Southwest deal was found by Cheapflights users on 7/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 9/277:40 am
PDX
- TYS
1 stop6h 35m
Southwest
Sat 10/32:55 pm
TYS
- PDX
2 stops9h 30m
Southwest
Deal found 7/4![Southwest logo]()
$462
This United Airlines deal was found by Cheapflights users on 7/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 9/48:25 am
PDX
- TYS
1 stop8h 59m
United Airlines
Mon 9/77:00 am
TYS
- PDX
1 stop7h 28m
United Airlines
Deal found 7/8![United Airlines logo]()
$446
This Delta deal was found by Cheapflights users on 7/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 8/510:55 pm
PDX
- TYS
1 stop9h 16m
Delta
Wed 8/124:38 pm
TYS
- PDX
1 stop8h 06m
Delta
Deal found 7/6![Delta logo]()
$457
This Southwest deal was found by Cheapflights users on 7/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 8/57:05 am
PDX
- TYS
2 stops8h 50m
Southwest
Wed 8/121:55 pm
TYS
- PDX
2 stops11h 20m
Southwest
Deal found 7/6![Southwest logo]()
$467
This United Airlines deal was found by Cheapflights users on 7/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 9/275:00 am
PDX
- TYS
1 stop7h 52m
United Airlines
Sat 10/310:42 am
TYS
- PDX
1 stop8h 14m
United Airlines
Deal found 7/4![United Airlines logo]()
$457
This United Airlines deal was found by Cheapflights users on 7/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 8/311:30 pm
PDX
- TYS
1 stop8h 12m
United Airlines
Fri 8/76:00 am
TYS
- PDX
1 stop8h 38m
United Airlines
Deal found 7/4![United Airlines logo]()
$457
This United Airlines deal was found by Cheapflights users on 7/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 8/511:59 pm
PDX
- TYS
1 stop8h 20m
United Airlines
Wed 8/127:00 am
TYS
- PDX
1 stop7h 28m
United Airlines
Deal found 7/5![United Airlines logo]()
$457
This United Airlines deal was found by Cheapflights users on 7/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 9/147:15 pm
PDX
- TYS
2 stops11h 42m
United Airlines
Sat 9/195:45 am
TYS
- PDX
2 stops12h 20m
United Airlines
Deal found 7/8![United Airlines logo]()
$495
Last-minute flights from Portland to KnoxvilleDiscover last-minute flight deals from Portland to Knoxville. Data last updated July 9, 2026 and is based on user searches.
Discover last-minute flight deals from Portland to Knoxville. Data last updated July 9, 2026 and is based on user searches.
This Kiwi.com deal was found by Cheapflights users on 7/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 7/295:21 pm
PDX
- TYS
1 stop17h 30m
Multiple Airlines
Wed 8/128:19 pm
TYS
- PDX
1 stop23h 32m
Multiple Airlines
Deal found 7/8![Multiple Airlines logo]()
$329
This Kiwi.com deal was found by Cheapflights users on 7/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 7/315:49 pm
PDX
- TYS
2 stops25h 12m
Multiple Airlines
Sun 8/27:00 am
TYS
- PDX
1 stop12h 51m
Multiple Airlines
Deal found 7/7![Multiple Airlines logo]()
$357
This American Airlines deal was found by Cheapflights users on 7/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 8/312:45 am
PDX
- TYS
1 stop9h 08m
American Airlines
Tue 8/116:03 am
TYS
- PDX
1 stop7h 51m
American Airlines
Deal found 7/8![American Airlines logo]()
$323
This Delta deal was found by Cheapflights users on 7/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 8/610:55 pm
PDX
- TYS
1 stop7h 41m
Delta
Thu 8/134:38 pm
TYS
- PDX
1 stop8h 06m
Delta
Deal found 7/7![Delta logo]()
$293
This Kiwi.com deal was found by Cheapflights users on 7/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 8/612:20 pm
PDX
- TYS
2 stops28h 58m
Multiple Airlines
Thu 8/137:00 am
TYS
- PDX
1 stop12h 51m
Multiple Airlines
Deal found 7/7![Multiple Airlines logo]()
$378
This American Airlines deal was found by Cheapflights users on 7/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 8/2211:58 am
PDX
- TYS
1 stop8h 20m
American Airlines
Sat 8/296:03 am
TYS
- PDX
1 stop7h 51m
American Airlines
Deal found 7/7![American Airlines logo]()
$348
One-way flights from Portland to KnoxvilleSearch for one-way flight options from Portland to Knoxville. Find affordable one-way fares based on user searches. Data last updated July 9, 2026.
Search for one-way flight options from Portland to Knoxville. Find affordable one-way fares based on user searches. Data last updated July 9, 2026.
This American Airlines deal was found by Cheapflights users on 7/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 8/610:59 pm
PDX
- TYS
1 stop7h 44m
American Airlines
Deal found 7/8![American Airlines logo]()
$147
This Kiwi.com deal was found by Cheapflights users on 7/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 8/195:56 pm
PDX
- TYS
1 stop16h 53m
Multiple Airlines
Deal found 7/5![Multiple Airlines logo]()
$170
This Kiwi.com deal was found by Cheapflights users on 7/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 8/166:49 pm
PDX
- TYS
2 stops25h 42m
Multiple Airlines
Deal found 7/5![Multiple Airlines logo]()
$181
This Booking.com deal was found by Cheapflights users on 7/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Booking.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 7/285:16 pm
PDX
- TYS
1 stop23h 08m
Frontier
Deal found 7/6![Frontier logo]()
$188
This Kiwi.com deal was found by Cheapflights users on 7/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 8/2212:20 pm
PDX
- TYS
2 stops20h 45m
Multiple Airlines
Deal found 7/5![Multiple Airlines logo]()
$189
This Kiwi.com deal was found by Cheapflights users on 7/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 8/216:17 pm
PDX
- TYS
2 stops22h 45m
Multiple Airlines
Deal found 7/5![Multiple Airlines logo]()
$195
This Kiwi.com deal was found by Cheapflights users on 7/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 10/1712:34 pm
PDX
- TYS
2 stops25h 30m
Multiple Airlines
Deal found 7/5![Multiple Airlines logo]()
$201
This Kiwi.com deal was found by Cheapflights users on 7/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 9/275:30 pm
PDX
- TYS
2 stops20h 13m
Multiple Airlines
Deal found 7/8![Multiple Airlines logo]()
$204
This Kiwi.com deal was found by Cheapflights users on 7/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 8/201:47 pm
PDX
- TYS
1 stop28h 59m
Multiple Airlines
Deal found 7/5![Multiple Airlines logo]()
$208
This Delta deal was found by Cheapflights users on 7/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 10/1810:50 pm
PDX
- TYS
1 stop9h 11m
Delta
Deal found 7/8![Delta logo]()
$229
Find flight deals from Portland to Knoxville
Discover tips and strategies to find the most affordable flight options for your journey from Portland (PDX) to Knoxville (TYS). Learn about various techniques such as flexible date searches, comparing prices across and setting up price alerts. Use these methods to find the cheapest flights available for your travel needs. Data last updated July 9, 2026.
Most accurate provider | FlightHub 3 stars |
|---|---|
Most trusted provider | FlightHub 3 stars |
Round-trip from | $293 (Delta) |
One-way from | $147 (American Airlines) |
Popular in | May |
Cheapest in | August |
Average price | $536 |
Cheapflights Fare Finder
Customize your flight search to find flights from Portland to Knoxville that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated July 9, 2026.
Use the filters below to find and compare flights from Portland to Knoxville that are best for you.
Fly from
Fly to
Route
Depart
Return
Cheapest round-trip
PortlandKnoxville
PDX - TYS
PDXTYS
Portland
Sun 10/4
10:57 pm-11:18 am
1 stop9h 21m
Knoxville McGhee Tyson
Thu 10/8
6:57 pm-11:43 pm
1 stop7h 46m
$375
Quickest round-trip
PortlandKnoxville
PDX - TYS
PDXTYS
Portland
Wed 9/2
10:35 am-8:53 pm
1 stop7h 18m
Knoxville McGhee Tyson
Sat 9/5
6:02 pm-10:50 pm
1 stop7h 48m
$403
PortlandKnoxville
PDX - TYS
PDXTYS
Portland
Fri 9/4
8:25 am-8:24 pm
1 stop8h 59m
Knoxville McGhee Tyson
Mon 9/7
7:00 am-11:28 am
1 stop7h 28m
$446
PortlandKnoxville
PDX - TYS
PDXTYS
Portland
Wed 8/5
10:55 pm-11:11 am
1 stop9h 16m
Knoxville McGhee Tyson
Wed 8/12
4:38 pm-9:44 pm
1 stop8h 06m
$457
PortlandKnoxville
PDX - TYS
PDXTYS
Portland
Sun 9/27
5:00 am-3:52 pm
1 stop7h 52m
Knoxville McGhee Tyson
Sat 10/3
10:42 am-3:56 pm
1 stop8h 14m
$457
PortlandKnoxville
PDX - TYS
PDXTYS
Portland
Mon 8/3
11:30 pm-10:42 am
1 stop8h 12m
Knoxville McGhee Tyson
Fri 8/7
6:00 am-11:38 am
1 stop8h 38m
$457
PortlandKnoxville
PDX - TYS
PDXTYS
Portland
Wed 8/5
11:59 pm-11:19 am
1 stop8h 20m
Knoxville McGhee Tyson
Wed 8/12
7:00 am-11:28 am
1 stop7h 28m
$457
PortlandKnoxville
PDX - TYS
PDXTYS
Portland
Sun 9/27
7:40 am-5:15 pm
1 stop6h 35m
Knoxville McGhee Tyson
Sat 10/3
2:55 pm-9:25 pm
2 stops9h 30m
$462
PortlandKnoxville
PDX - TYS
PDXTYS
Portland
Wed 8/5
7:05 am-6:55 pm
2 stops8h 50m
Knoxville McGhee Tyson
Wed 8/12
1:55 pm-10:15 pm
2 stops11h 20m
$467
PortlandKnoxville
PDX - TYS
PDXTYS
Portland
Mon 9/14
7:15 pm-9:57 am
2 stops11h 42m
Knoxville McGhee Tyson
Sat 9/19
5:45 am-3:05 pm
2 stops12h 20m
$495
Showing 1-10 of 19 resultsSorted by cheapest first
Compare providers for flights from Portland to Knoxville
Provider information is updated monthly. Please note that these providers often have deals for this flight, but the availability may vary on a day-by-day basis on Cheapflights.
Use the table below to compare price accuracy, trust ratings, and cancellation policies for each provider offering flight deals from Portland to Knoxville in July.
| Provider | Price Accuracy | Trust Score* |
|---|---|---|
| Price Accuracy1 star | Trust Score*3 stars | |
| Price Accuracy3 stars | Trust Score*3 stars |
- Most accurate provider: When it comes to deals on Portland-Knoxville flights, users find the pricing of FlightHub to be most consistent on Cheapflights vs. FlightHub Users can find the same prices on Portland-Knoxville flight deals on Cheapflights vs. FlightHub >95% of the time. Price accuracy is based on data collected from Portland-Knoxville flight searches over the past month and is updated monthly.
- Most trusted provider: When it comes to deals on Portland-Knoxville flights, Cheapflights users trust FlightHub the most. FlightHub has received a user feedback score of 3 out of 3 stars (3 being the best), meaning they have been trusted the most by Cheapflights users looking for Portland-Knoxville flight deals. Provider user feedback score is based on Cheapflights searches over the past month and is updated monthly.
Best time to book a flight from Portland to Knoxville
Have a flexible travel schedule? Discover the best time to fly to Knoxville from Portland with our price prediction graph.
PDX-TYS
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.
Cheapflights Insights
Everything you need to know about your flight from Portland to Knoxville
How far ahead should I book a flight from Portland to Knoxville?
The best time to book flights from Portland to Knoxville is 45 days before your desired departure date. The cost of your flight will likely increase significantly if you book two weeks in advance of your flight.
What is the cheapest month to book a flight from Portland to Knoxville?
Currently, August is the cheapest month in which you can book a flight from Portland to Knoxville (average of $393). Flying from Portland to Knoxville in May is currently the most expensive (average of $611). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.
How much does it cost to fly round-trip from Portland to Knoxville?
Reviews of airlines servicing Knoxville
Get insights into the airlines that provide service to Knoxville. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Knoxville. Reviews last updated July 9, 2026.
Read through reviews of airlines operating flights from Portland to Knoxville, such as Delta,United Airlines, andAmerican Airlines. Reviews also offer insight into each airline's entertainment options, comfort, food, crew/service, and boarding process.
Food
7.2
Comfort
7.8
Boarding
8.1
Crew
8.5
Overall
7.8
Entertainment
7.8
Reviews
1 / 20
10.0
ExcellentAnonymous,May 2026
SEA - KOA
Food
7.2
Comfort
7.8
Boarding
8.1
Crew
8.5
Overall
7.8
Entertainment
7.8
Reviews
1 / 20
10.0
ExcellentAnonymous,May 2026
SEA - KOA
Food
7.2
Comfort
7.8
Boarding
8.1
Crew
8.5
Overall
7.8
Entertainment
7.8
Reviews
1 / 20
10.0
ExcellentAnonymous,May 2026
SEA - KOA
Food
7.2
Comfort
7.8
Boarding
8.1
Crew
8.5
Overall
7.8
Entertainment
7.8
Reviews
1 / 20
10.0
ExcellentAnonymous,May 2026
SEA - KOA
Related info for your journey
Find useful and relevant information for your journey from Portland to Knoxville. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.
Traveling to a place near Knoxville?
Book flights to Knoxville if you plan to visit one of these locationsCherokee
Crossville
Morristown
Bryson City
Murphy
Alcoa
Browse thousands of different options on Cheapflights for your next trip
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Alternative routes for Portland to Knoxville
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Complete your trip
Complete your trip to Knoxville by adding a car rental and/or hotel reservation to your travel itinerary.
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Find flights from Portland to Knoxville, based on your preferred cabin class, be it economy, premium economy, business, or first class.
Other flights to Knoxville
Explore flights to Knoxville departing from other origins. Flights are based on user searches made on Cheapflights and were last updated on July 9, 2026.
Portland and Knoxville flights
Browse other Portland and Knoxville flight options. Last updated on July 9, 2026.
Other flights from Portland
Browse through other flights departing from Portland. Flights are based on user searches made on Cheapflights and were last updated on July 9, 2026.
Popular flight searches
Check out other popular destinations found by fellow travelers in 2026
Top 3 airlines flying from Portland to Knoxville
Discover the top 3 airlines that operate flights from Portland to Knoxville. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated July 9, 2026.
| Airline | Cheapest | Average | Flexibility | On-time |
|---|---|---|---|---|
| Cheapest$268 | Average$498 | FlexibilityNo cancel fee | On-timeN/A | |
| Cheapest$304 | Average$472 | FlexibilityNo cancel fee | On-time71% | |
| Cheapest$328 | Average$536 | FlexibilityNo cancel fee | On-time69% |