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$135+ Cheap flights from Portland to Knoxville (PDX - TYS)

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 11/19. Fares are subject to change and may not be available on all flights or dates of travel.
PDX — TYS
Nov 29 — Dec 61
Sat 11/29
Sat 12/6
1 adult, Economy
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Cheapflights Tip: The best prices from Portland to Knoxville McGhee Tyson are usually found in August or February, booked 75 days in advance, depart on a Tuesday or Wednesday and return on a Wednesday

Cheap flight deals from Portland to Knoxville

Discover tips and strategies to find the most affordable flight options for your journey from Portland (PDX) to Knoxville (TYS). Learn about various techniques such as flexible date searches, comparing prices across and setting up price alerts. Use these methods to find the cheapest flights available for your travel needs. Data last updated October 30, 2025.

Most accurate provider

eDreams
3 stars

Most trusted provider

eDreams
3 stars

Round-trip from

$206
(Kiwi.com)

One-way from

$135
(American Airlines)

Popular in

December

Cheapest in

August

Average price

$429
Provider with most accurate pricing for Portland-Knoxville McGhee Tyson flight deals.
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Provider most trusted by Cheapflights users for Portland-Knoxville McGhee Tyson flights.
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From Portland to Knoxville McGhee Tyson
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One-way flight from Portland to Knoxville McGhee Tyson
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Highest demand for flights based on searches. 10% potential increase in price ($54 potential increase over avg. RT price).
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Cheapest flight prices on average. 4% potential price decrease ($20 potential savings vs. average RT price).
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Average for round-trip flights in October 2025
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Find flight deals from Portland to Knoxville

Cheapest flights from Portland to Knoxville
Explore the most affordable flight options available from Portland to Knoxville. Find the lowest fares from popular airlines and budget airlines, with prices last updated on October 30, 2025.

This Delta deal was found by Cheapflights users on 10/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 12/910:10 pmPDX - TYS
1 stop8h 28mDelta
Sat 12/135:36 pmTYS - PDX
1 stop7h 43mDelta
Deal found 10/29$269
This Kiwi.com deal was found by Cheapflights users on 10/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 11/206:12 pmPDX - TYS
2 stops18h 41mMultiple Airlines
Sun 11/236:30 amTYS - PDX
1 stop11h 37mMultiple Airlines
Deal found 10/30$299
This Kiwi.com deal was found by Cheapflights users on 10/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 12/18:49 amPDX - TYS
1 stop10h 58mMultiple Airlines
Thu 12/46:30 amTYS - PDX
1 stop8h 26mMultiple Airlines
Deal found 10/30$339
This Delta deal was found by Cheapflights users on 10/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 12/510:10 pmPDX - TYS
1 stop8h 46mDelta
Tue 12/93:57 pmTYS - PDX
1 stop9h 22mDelta
Deal found 10/29$353
This Kiwi.com deal was found by Cheapflights users on 10/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 11/173:26 pmPDX - TYS
2 stops20h 48mMultiple Airlines
Fri 11/214:48 pmTYS - PDX
1 stop25h 19mMultiple Airlines
Deal found 10/29$421
This United Airlines deal was found by Cheapflights users on 10/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 12/512:55 pmPDX - TYS
1 stop7h 49mUnited Airlines
Mon 12/87:05 amTYS - PDX
1 stop8h 07mUnited Airlines
Deal found 10/30$437
This Kiwi.com deal was found by Cheapflights users on 10/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 11/131:21 pmPDX - TYS
2 stops24h 34mMultiple Airlines
Mon 11/178:00 amTYS - PDX
1 stop13h 31mMultiple Airlines
Deal found 10/29$439

Cheapflights Fare Finder

 
Customize your flight search to find flights from Portland to Knoxville that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated October 30, 2025.
Use the filters below to find and compare flights from Portland to Knoxville that are best for you.

Fly from

Portland

Fly to

Knoxville

Route

Depart

Return

Price

PortlandKnoxville

PDX - TYS

PDXTYS

Portland

Mon 12/8

12:32 am-2:52 pm

2 stops11h 20m

Knoxville McGhee Tyson

Sat 12/13

5:36 pm-10:19 pm

1 stop7h 43m

$274

PortlandKnoxville

PDX - TYS

PDXTYS

Portland

Mon 12/1

8:49 am-10:47 pm

1 stop10h 58m

Knoxville McGhee Tyson

Thu 12/4

6:30 am-11:56 am

1 stop8h 26m

$339

PortlandKnoxville

PDX - TYS

PDXTYS

Portland

Fri 12/5

12:55 pm-11:44 pm

1 stop7h 49m

Knoxville McGhee Tyson

Tue 12/9

5:54 pm-10:15 pm

1 stop7h 21m

$437

PortlandKnoxville

PDX - TYS

PDXTYS

Portland

Fri 12/5

11:59 pm-1:05 pm

2 stops10h 06m

Knoxville McGhee Tyson

Mon 12/8

12:02 pm-8:50 pm

2 stops11h 48m

$477

PortlandKnoxville

PDX - TYS

PDXTYS

Portland

Thu 11/20

1:15 pm-11:44 pm

1 stop7h 29m

Knoxville McGhee Tyson

Sun 11/23

2:25 pm-8:29 pm

1 stop9h 04m

$497

PortlandKnoxville

PDX - TYS

PDXTYS

Portland

Wed 11/19

12:35 am-2:48 pm

2 stops11h 13m

Knoxville McGhee Tyson

Sun 11/23

6:35 am-12:48 pm

1 stop9h 13m

$502

PortlandKnoxville

PDX - TYS

PDXTYS

Portland

Wed 1/28

12:40 am-1:52 pm

2 stops10h 12m

Knoxville McGhee Tyson

Sun 2/1

7:30 am-6:50 pm

2 stops14h 20m

$507

PortlandKnoxville

PDX - TYS

PDXTYS

Portland

Wed 11/19

2:07 pm-12:08 am

1 stop7h 01m

$135

PortlandKnoxville

PDX - TYS

PDXTYS

Portland

Tue 11/18

12:35 am-2:48 pm

2 stops11h 13m

$140

PortlandKnoxville

PDX - TYS

PDXTYS

Portland

Wed 11/19

6:00 am-10:55 pm

3 stops13h 55m

$195

Flights are sorted by cheapest round-trip flights first.

Deals found on 10/29

Compare providers for flights from Portland to Knoxville

Provider information is updated monthly. Please note that these providers often have deals for this flight, but the availability may vary on a day-by-day basis on Cheapflights.
Use the table below to compare price accuracy, trust ratings, and cancellation policies for each provider offering flight deals from Portland to Knoxville in October.
ProviderPrice AccuracyTrust Score*
ExpediaPrice Accuracy2 starsTrust Score*3 stars
FlightHubPrice Accuracy3 starsTrust Score*1 star
eDreamsPrice Accuracy3 starsTrust Score*3 stars

*The Trust Score is based on feedback from users after their booking experience. It measures overall satisfaction, helping us identify issues like hidden fees, problems during the ticketing process, and the quality of customer service. This score is our best indicator of the provider's quality and reliability.

  • Most accurate provider: When it comes to deals on Portland-Knoxville flights, users find the pricing of eDreams to be most consistent on Cheapflights vs. eDreams Users can find the same prices on Portland-Knoxville flight deals on Cheapflights vs. eDreams >95% of the time. Price accuracy is based on data collected from Portland-Knoxville flight searches over the past month and is updated monthly.
  • Most trusted provider: When it comes to deals on Portland-Knoxville flights, Cheapflights users trust eDreams the most. eDreams has received a user feedback score of 3 out of 3 stars (3 being the best), meaning they have been trusted the most by Cheapflights users looking for Portland-Knoxville flight deals. Provider user feedback score is based on Cheapflights searches over the past month and is updated monthly.

Best time to book a flight from Portland to Knoxville

Have a flexible travel schedule? Discover the best time to fly to Knoxville from Portland with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Portland to Knoxville

How far ahead should I book a flight from Portland to Knoxville?

Use this chart to determine the optimal time to book a round-trip flight from Portland to Knoxville. Price data was last updated on October 24, 2025.

The best time to book flights from Portland to Knoxville is 75 days before your desired departure date. The cost of your flight will likely increase significantly if you book two weeks in advance of your flight.

What is the cheapest month to book a flight from Portland to Knoxville?

Currently, July is the cheapest month in which you can book a flight from Portland to Knoxville (average of $128). Flying from Portland to Knoxville in May is currently the most expensive (average of $285). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

What is the cheapest time of day to fly from PDX to TYS?

Find hourly flight availability from Portland to Knoxville. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated October 30, 2025.

When flying from Portland to Knoxville, the time of day you fly usually plays a role in the price. Save by searching for a flight in the afternoon, which can drop the price by up to 27% versus a flight in the evening.

Reviews of airlines servicing Knoxville

Get insights into the airlines that provide service to Knoxville. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Knoxville. Reviews last updated October 30, 2025.
Read through reviews of airlines operating flights from Portland to Knoxville, such as Delta, United Airlines, and American Airlines. Reviews also offer insight into each airline's entertainment options, comfort, food, crew/service, and boarding process.
Delta
7.9
Good
7,998 reviews

Overall

7.9

Entertainment

7.9

Boarding

8.2

Food

7.3

Crew

8.5

Comfort

7.9

Reviews

1 / 20
8.0
Excellent

Matthew,Oct 2025

GSP - ATL

This is always a full flight since it is the connecting route to primary destinations through Atlanta. That said, the crew handles the full load well. Not much more to say, it is a short flight with no in-flight services due to the length.
Delta
7.9
Good
7,998 reviews
Delta
7.9
Good
7,998 reviews

Overall

7.9

Entertainment

7.9

Boarding

8.2

Food

7.3

Crew

8.5

Comfort

7.9

Reviews

1 / 20
8.0
Excellent

Matthew,Oct 2025

GSP - ATL

This is always a full flight since it is the connecting route to primary destinations through Atlanta. That said, the crew handles the full load well. Not much more to say, it is a short flight with no in-flight services due to the length.
United Airlines
7.4
Good
8,998 reviews
Delta
7.9
Good
7,998 reviews

Overall

7.9

Entertainment

7.9

Boarding

8.2

Food

7.3

Crew

8.5

Comfort

7.9

Reviews

1 / 20
8.0
Excellent

Matthew,Oct 2025

GSP - ATL

This is always a full flight since it is the connecting route to primary destinations through Atlanta. That said, the crew handles the full load well. Not much more to say, it is a short flight with no in-flight services due to the length.
American Airlines
7.2
Good
11,035 reviews
Delta
7.9
Good
7,998 reviews

Overall

7.9

Entertainment

7.9

Boarding

8.2

Food

7.3

Crew

8.5

Comfort

7.9

Reviews

1 / 20
8.0
Excellent

Matthew,Oct 2025

GSP - ATL

This is always a full flight since it is the connecting route to primary destinations through Atlanta. That said, the crew handles the full load well. Not much more to say, it is a short flight with no in-flight services due to the length.
Frontier
5.8
Fair
3,122 reviews
Delta
7.9
Good
7,998 reviews

Overall

7.9

Entertainment

7.9

Boarding

8.2

Food

7.3

Crew

8.5

Comfort

7.9

Reviews

1 / 20
8.0
Excellent

Matthew,Oct 2025

GSP - ATL

This is always a full flight since it is the connecting route to primary destinations through Atlanta. That said, the crew handles the full load well. Not much more to say, it is a short flight with no in-flight services due to the length.

Related info for your journey

Find useful and relevant information for your journey from Portland to Knoxville. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • How long is the flight from Portland to Knoxville?

    For as low as $437, Delta can have you in Knoxville from Portland in 7h 49m. There are 2107 mi between Portland and Knoxville. This flight may include one or multiple stops.

  • What are the cheapest airlines flying from Portland to Knoxville round-trip?

    Cheapflights users have booked flights from Portland to Knoxville round-trip from $195. Other airlines that can offer you cheap pricing are United Airlines, from $258, and American Airlines, from $293. Frontier is 57% cheaper than the average price of flights available within the next 90 days to this destination.

  • What are the cheapest airlines to fly from Portland to Knoxville one-way?

    The cheapest airline one-way is American Airlines, with whom users have recently found tickets for as low as $135. However, be on the lookout for offers from Delta and United Airlines, as they are both options that can get you from Portland to Knoxville for a low price.

  • Can I find deals for flights from Portland to Knoxville that include hotel bookings?

    Yes. In addition to deals on Portland to Knoxville flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Portland to Knoxville?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Portland to Knoxville.

  • Can I find deals for business class flights from Portland to Knoxville?

    Yes. Cheapflights offers flight deals from Portland to Knoxville by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Portland to Knoxville?

    Currently, July is the cheapest month in which you can book a flight from Portland to Knoxville (average of $128). Flying from Portland to Knoxville in May is currently the most expensive (average of $285). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

Traveling to a place near Knoxville?

Book flights to Knoxville if you plan to visit one of these locations
Morristown
Cherokee
Crossville
Corbin
Bryson City
Alcoa
Oak Ridge
Murphy

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Top 4 airlines flying from Portland to Knoxville

Discover the top 4 airlines that operate flights from Portland to Knoxville. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated October 30, 2025.
AirlineCheapestAverageFlexibilityOn-time
FrontierCheapest$195Average$278FlexibilityNo cancel feeOn-time62%
United AirlinesCheapest$258Average$468FlexibilityNo cancel feeOn-time69%
American AirlinesCheapest$293Average$458FlexibilityNo cancel feeOn-time71%
DeltaCheapest$298Average$460FlexibilityNo cancel feeOn-timeN/A

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