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$166+ Cheap flights from Portland to Knoxville (PDX - TYS)

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 7/17. Fares are subject to change and may not be available on all flights or dates of travel.
PDX — TYS
Jun 17 — Jun 241
Tue 6/17
Tue 6/24
1 adult, Economy
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Cheapflights Tip: The best prices from Portland to Knoxville McGhee Tyson are usually found in February or September, booked 88 days in advance, depart on a Tuesday or Wednesday and return on a Wednesday

Cheap flight deals from Portland to Knoxville

Discover tips and strategies to find the most affordable flight options for your journey from Portland (PDX) to Knoxville (TYS). Learn about various techniques such as flexible date searches, comparing prices across and setting up price alerts. Use these methods to find the cheapest flights available for your travel needs. Data last updated June 12, 2025.

Round-trip from

$251
(American Airlines)

One-way from

$166
(Trip.com)

Popular in

December

Cheapest in

February

Average price

$461
From Portland to Knoxville McGhee Tyson
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One-way flight from Portland to Knoxville McGhee Tyson
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Highest demand for flights based on searches. 8% potential increase in price ($44 potential increase over avg. RT price).
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Cheapest flight prices on average. 3% potential price decrease ($14 potential savings vs. average RT price).
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Average for round-trip flights in June 2025
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Find flight deals from Portland to Knoxville

Cheapest flights from Portland to Knoxville
Explore the most affordable flight options available from Portland to Knoxville. Find the lowest fares from popular airlines and budget airlines, with prices last updated on June 12, 2025.

This American Airlines deal was found by Cheapflights users on 6/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 9/1711:42 amPDX - TYS
1 stop9h 39mAmerican Airlines
Wed 9/246:00 amTYS - PDX
1 stop7h 52mAmerican Airlines
Deal found 6/12$251
This Delta deal was found by Cheapflights users on 6/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 11/810:15 amPDX - TYS
2 stops9h 44mDelta
Tue 11/116:10 pmTYS - PDX
1 stop7h 22mDelta
Deal found 6/9$276
This Mytrip deal was found by Cheapflights users on 6/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Mytrip is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 7/2011:59 pmPDX - TYS
1 stop13h 13mMultiple Airlines
Sun 7/277:10 amTYS - PDX
2 stops27h 22mMultiple Airlines
Deal found 6/9$299
This Frontier deal was found by Cheapflights users on 6/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Frontier is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 8/216:27 amPDX - TYS
1 stop10h 14mFrontier
Sun 8/248:33 pmTYS - PDX
1 stop6h 42mFrontier
Deal found 6/12$301
This Mytrip deal was found by Cheapflights users on 6/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Mytrip is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 7/188:22 amPDX - TYS
2 stops34h 20mAllegiant Air
Sun 7/207:10 amTYS - PDX
2 stops27h 22mAllegiant Air
Deal found 6/10$317
This United Airlines deal was found by Cheapflights users on 6/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 9/177:35 pmPDX - TYS
2 stops15h 03mUnited Airlines
Wed 9/247:00 amTYS - PDX
2 stops16h 03mUnited Airlines
Deal found 6/12$405
This Alaska Airlines deal was found by Cheapflights users on 6/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Alaska Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 7/1811:28 amPDX - TYS
1 stop9h 24mAlaska Airlines
Sat 7/262:02 pmTYS - PDX
1 stop7h 45mAlaska Airlines
Deal found 6/12$434

Cheapflights Fare Finder

Customize your flight search to find flights from Portland to Knoxville that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated June 12, 2025.
Use the filters below to find and compare flights from Portland to Knoxville that are best for you.

Fly from

Portland

Fly to

Knoxville

Route

Depart

Return

Price

PortlandKnoxville

PDX - TYS

PDXTYS

Portland

Fri 7/4

9:55 pm-8:34 am

1 stop7h 39m

Knoxville McGhee Tyson

Wed 7/9

2:48 pm-8:47 pm

1 stop8h 59m

$279

PortlandKnoxville

PDX - TYS

PDXTYS

Portland

Sun 7/20

11:59 pm-4:12 pm

1 stop13h 13m

Knoxville McGhee Tyson

Sun 7/27

7:10 am-7:32 am

2 stops27h 22m

$299

PortlandKnoxville

PDX - TYS

PDXTYS

Portland

Thu 8/21

6:27 am-7:41 pm

1 stop10h 14m

Knoxville McGhee Tyson

Sun 8/24

8:33 pm-12:15 am

1 stop6h 42m

$301

PortlandKnoxville

PDX - TYS

PDXTYS

Portland

Thu 7/3

11:20 pm-10:27 am

1 stop8h 07m

Knoxville McGhee Tyson

Tue 7/15

5:00 pm-10:33 pm

1 stop8h 33m

$309

PortlandKnoxville

PDX - TYS

PDXTYS

Portland

Tue 7/15

11:11 pm-10:14 am

1 stop8h 03m

Knoxville McGhee Tyson

Tue 8/5

6:15 pm-11:18 pm

1 stop8h 03m

$311

PortlandKnoxville

PDX - TYS

PDXTYS

Portland

Fri 7/18

8:22 am-9:42 pm

2 stops34h 20m

Knoxville McGhee Tyson

Sun 7/20

7:10 am-7:32 am

2 stops27h 22m

$317

PortlandKnoxville

PDX - TYS

PDXTYS

Portland

Fri 7/18

11:28 am-11:52 pm

1 stop9h 24m

Knoxville McGhee Tyson

Sat 7/26

2:02 pm-6:47 pm

1 stop7h 45m

$434

PortlandKnoxville

PDX - TYS

PDXTYS

Portland

Thu 7/17

11:55 pm-4:12 pm

1 stop13h 17m

$166

PortlandKnoxville

PDX - TYS

PDXTYS

Portland

Wed 7/9

12:25 pm-4:29 pm

1 stop25h 04m

$261

PortlandKnoxville

PDX - TYS

PDXTYS

Portland

Wed 7/16

6:15 am-11:59 pm

2 stops14h 44m

$303

Flights are sorted by cheapest round-trip flights first.

Deals found on 6/12

Showing 1-10 of 13 results
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Best time to book a flight from Portland to Knoxville

Have a flexible travel schedule? Discover the best time to fly to Knoxville from Portland with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Portland to Knoxville

How far ahead should I book a flight from Portland to Knoxville?

Use this chart to determine the optimal time to book a round-trip flight from Portland to Knoxville. Price data was last updated on June 9, 2025.

The best time to book flights from Portland to Knoxville is 88 days before your desired departure date. The cost of your flight will likely increase significantly if you book two weeks in advance of your flight.

What is the cheapest month to book a flight from Portland to Knoxville?

Currently, January is the cheapest month in which you can book a flight from Portland to Knoxville (average of $296). Flying from Portland to Knoxville in March is currently the most expensive (average of $376). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

What is the cheapest time of day to fly from PDX to TYS?

Find hourly flight availability from Portland to Knoxville. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated June 12, 2025.

When flying from Portland to Knoxville, the time of day you fly usually plays a role in the price. Save by searching for a flight at noon, which can drop the price by up to 4% versus a flight in the afternoon.

Rainfall in Knoxville by month

Plan your trip to Knoxville by taking into account the average rainfall totals by month.

In terms of precipitation, rainfall in Knoxville ranges from 2.7 - 4.8 inches per month. March is typically the wettest month, when rainfall can reach 4.8 in. October is typically the driest time to visit Knoxville when rainfall is around 2.7 in.

Temperature in Knoxville by month

Plan your trip to Knoxville by taking into account the average temperature totals by month.

If weather is an important factor for your trip to Knoxville, use this chart to help with planning. For those seeking warmer temperatures, July is the ideal time of year to visit, when temperatures reach an average of 78.8 F. Travelers looking to avoid the cold should look outside of January, when temperatures are typically at their lowest (around 39.2 F).

Reviews of airlines servicing Knoxville

Get insights into the airlines that provide service to Knoxville. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Knoxville. Reviews last updated June 12, 2025.
Peruse reviews from past customers who have flown with Alaska Airlines, Delta and United Airlines from Portland to Knoxville to help guide your decision. Reviews also offer insight into each airline's entertainment options, comfort, food, crew/service, and boarding process.
Alaska Airlines
8.0
Very good
10,000 reviews

Boarding

8.1

Comfort

7.8

Entertainment

7.1

Overall

8.0

Food

7.1

Crew

8.5

Reviews

1 / 20
10.0
Excellent

James,Apr 2025

LAX - SFO

Good flight except the uncontrollable cold air from the ceiling.
Alaska Airlines
8.0
Very good
10,000 reviews
Alaska Airlines
8.0
Very good
10,000 reviews

Boarding

8.1

Comfort

7.8

Entertainment

7.1

Overall

8.0

Food

7.1

Crew

8.5

Reviews

1 / 20
10.0
Excellent

James,Apr 2025

LAX - SFO

Good flight except the uncontrollable cold air from the ceiling.
Delta
8.0
Very good
7,946 reviews
Alaska Airlines
8.0
Very good
10,000 reviews

Boarding

8.1

Comfort

7.8

Entertainment

7.1

Overall

8.0

Food

7.1

Crew

8.5

Reviews

1 / 20
10.0
Excellent

James,Apr 2025

LAX - SFO

Good flight except the uncontrollable cold air from the ceiling.
United Airlines
7.4
Good
8,790 reviews
Alaska Airlines
8.0
Very good
10,000 reviews

Boarding

8.1

Comfort

7.8

Entertainment

7.1

Overall

8.0

Food

7.1

Crew

8.5

Reviews

1 / 20
10.0
Excellent

James,Apr 2025

LAX - SFO

Good flight except the uncontrollable cold air from the ceiling.
Allegiant Air
7.3
Good
725 reviews
Alaska Airlines
8.0
Very good
10,000 reviews

Boarding

8.1

Comfort

7.8

Entertainment

7.1

Overall

8.0

Food

7.1

Crew

8.5

Reviews

1 / 20
10.0
Excellent

James,Apr 2025

LAX - SFO

Good flight except the uncontrollable cold air from the ceiling.
American Airlines
7.2
Good
10,000 reviews
Alaska Airlines
8.0
Very good
10,000 reviews

Boarding

8.1

Comfort

7.8

Entertainment

7.1

Overall

8.0

Food

7.1

Crew

8.5

Reviews

1 / 20
10.0
Excellent

James,Apr 2025

LAX - SFO

Good flight except the uncontrollable cold air from the ceiling.

Related info for your journey

Find useful and relevant information for your journey from Portland to Knoxville. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • What are the cheapest airlines flying from Portland to Knoxville round-trip?

    Cheapflights users have booked flights from Portland to Knoxville round-trip from $251. Other airlines that can offer you cheap pricing are Delta, from $276, and Frontier, from $301. American Airlines is 46% cheaper than the average price of flights available within the next 90 days to this destination.

  • What are the cheapest airlines to fly from Portland to Knoxville one-way?

    The cheapest airline one-way is Frontier, with whom users have recently found tickets for as low as $261. However, be on the lookout for offers from Delta and American Airlines, as they are both options that can get you from Portland to Knoxville for a low price.

  • Can I find deals for flights from Portland to Knoxville that include hotel bookings?

    Yes. In addition to deals on Portland to Knoxville flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Portland to Knoxville?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Portland to Knoxville.

  • Can I find deals for business class flights from Portland to Knoxville?

    Yes. Cheapflights offers flight deals from Portland to Knoxville by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Portland to Knoxville?

    Currently, January is the cheapest month in which you can book a flight from Portland to Knoxville (average of $296). Flying from Portland to Knoxville in March is currently the most expensive (average of $376). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

Traveling to a place near Portland?

Book flights to Portland if you plan to visit one of these locations
Morristown
Cherokee
Corbin
Maryville
Oak Ridge
Alcoa
Murphy

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Top 4 airlines flying from Portland to Knoxville

Discover the top 4 airlines that operate flights from Portland to Knoxville. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated June 12, 2025.
AirlineCheapestAverageFlexibilityOn-time
FrontierCheapest$168Average$284FlexibilityNo cancel feeOn-time62%
United AirlinesCheapest$278Average$512FlexibilityNo cancel feeOn-time69%
American AirlinesCheapest$288Average$458FlexibilityNo cancel feeOn-time71%
DeltaCheapest$308Average$440FlexibilityNo cancel feeOn-timeN/A

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