$69+ Cheap flights from Massachusetts to Knoxville (TYS)
This is the cheapest round-trip flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 11/14. Fares are subject to change and may not be available on all flights or dates of travel.
BOS — TYS
Dec 5 — Dec 121
Round-trip
1 adult, Economy
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Find cheap flights from Massachusetts to Knoxville with Cheapflights
1. Tell us where you want to go
Enter your travel information like dates, passengers, trip type (one-way or round trip), and preferred cabin class then click “Find deals”2. Select your favorite providers
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Review each provider’s pricing and select the best option for you! Book through your favorite provider’s website for a seamless experience.Cheap flight deals from Massachusetts to Knoxville
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Cheapest flights from Massachusetts to KnoxvilleExplore the most affordable flight options available from Massachusetts to Knoxville. Find the lowest fares from popular airlines and budget airlines, with prices last updated on November 5, 2026.
Explore the most affordable flight options available from Massachusetts to Knoxville. Find the lowest fares from popular airlines and budget airlines, with prices last updated on November 5, 2026.
This Cheapflightsfares deal was found by Cheapflights users on 11/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Cheapflightsfares is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 11/149:09 am -
Nonstop2h 30m
Thu 11/196:30 am -
Nonstop2h 15m
Deal found 11/2![Allegiant Air logo]()
$141
This Cheapflightsfares deal was found by Cheapflights users on 11/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Cheapflightsfares is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 12/179:31 am -
Nonstop2h 32m
Sun 12/206:30 am -
Nonstop2h 11m
Deal found 11/4![Allegiant Air logo]()
$163
This Cheapflightsfares deal was found by Cheapflights users on 11/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Cheapflightsfares is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 12/179:31 am -
Nonstop2h 32m
Thu 12/316:30 am -
Nonstop2h 11m
Deal found 11/1![Allegiant Air logo]()
$178
This Cheapflightsfares deal was found by Cheapflights users on 11/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Cheapflightsfares is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 12/209:31 am -
Nonstop2h 32m
Tue 12/226:15 am -
Nonstop2h 11m
Deal found 11/4![Allegiant Air logo]()
$193
This Cheapflightsfares deal was found by Cheapflights users on 11/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Cheapflightsfares is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 11/1210:19 am -
Nonstop2h 30m
Sat 11/146:00 am -
Nonstop2h 19m
Deal found 11/1![Allegiant Air logo]()
$197
This CheapOair deal was found by Cheapflights users on 10/31. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure CheapOair is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 12/1011:35 am -
Nonstop2h 36m
Sun 12/138:30 am -
Nonstop2h 15m
Deal found 10/31![Allegiant Air logo]()
$198
This CheapOair deal was found by Cheapflights users on 11/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure CheapOair is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 12/311:35 am -
Nonstop2h 36m
Sun 12/68:30 am -
Nonstop2h 15m
Deal found 11/4![Allegiant Air logo]()
$205
This American Airlines deal was found by Cheapflights users on 11/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 11/286:36 pm -
2 stops23h 07m
Sat 12/127:00 am -
1 stop11h 38m
Deal found 11/2![American Airlines logo]()
$449
This American Airlines deal was found by Cheapflights users on 11/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 11/175:36 pm -
1 stop17h 40m
Sat 11/2112:42 pm -
1 stop4h 39m
Deal found 11/2![American Airlines logo]()
$512
This American Airlines deal was found by Cheapflights users on 11/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 11/185:36 pm -
2 stops21h 45m
Sun 11/227:01 am -
2 stops10h 20m
Deal found 11/3![American Airlines logo]()
$538
This Delta deal was found by Cheapflights users on 11/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 11/194:00 pm -
1 stop5h 05m
Sun 11/225:40 am -
2 stops9h 43m
Deal found 11/3![Delta logo]()
$552
This American Airlines deal was found by Cheapflights users on 11/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 11/105:36 pm -
1 stop17h 40m
Fri 11/138:04 pm -
2 stops21h 03m
Deal found 11/2![American Airlines logo]()
$622
Best flights from Massachusetts to KnoxvilleDiscover carefully curated flight deals from Massachusetts to Knoxville that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated November 5, 2026.
Discover carefully curated flight deals from Massachusetts to Knoxville that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated November 5, 2026.
This United Airlines deal was found by Cheapflights users on 11/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 12/211:00 am -
2 stops8h 47m
Thu 12/37:45 pm -
1 stop4h 14m
Deal found 11/2![United Airlines logo]()
$276
This Southwest deal was found by Cheapflights users on 11/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 12/29:10 am -
2 stops10h 40m
Thu 12/35:15 pm -
1 stop5h 00m
Deal found 11/1![Southwest logo]()
$276
This American Airlines deal was found by Cheapflights users on 11/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 5/22:47 pm -
1 stop7h 10m
Thu 5/66:38 pm -
1 stop19h 44m
Deal found 11/3![American Airlines logo]()
$411
This United Airlines deal was found by Cheapflights users on 11/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 12/27:33 pm -
1 stop4h 26m
Wed 12/96:00 am -
2 stops8h 32m
Deal found 11/4![United Airlines logo]()
$276
This Delta deal was found by Cheapflights users on 11/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 11/194:00 pm -
1 stop5h 05m
Sun 11/225:40 am -
2 stops9h 43m
Deal found 11/3![Delta logo]()
$552
This Southwest deal was found by Cheapflights users on 11/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 1/215:45 am -
2 stops6h 30m
Mon 1/256:45 am -
2 stops9h 20m
Deal found 11/1![Southwest logo]()
$281
This United Airlines deal was found by Cheapflights users on 11/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 12/257:49 pm -
1 stop4h 26m
Thu 12/316:35 am -
1 stop6h 51m
Deal found 11/3![United Airlines logo]()
$371
This United Airlines deal was found by Cheapflights users on 11/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 11/233:01 pm -
1 stop5h 53m
Fri 11/275:45 am -
2 stops7h 46m
Deal found 11/2![United Airlines logo]()
$376
This American Airlines deal was found by Cheapflights users on 11/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 11/286:36 pm -
2 stops24h 58m
Sat 12/127:16 am -
2 stops11h 22m
Deal found 11/2![American Airlines logo]()
$455
This Southwest deal was found by Cheapflights users on 11/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 11/245:35 am -
2 stops6h 30m
Tue 12/11:00 pm -
2 stops9h 15m
Deal found 11/4![Southwest logo]()
$499
This American Airlines deal was found by Cheapflights users on 11/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 11/175:36 pm -
1 stop17h 40m
Sat 11/2112:42 pm -
1 stop4h 39m
Deal found 11/2![American Airlines logo]()
$512
This United Airlines deal was found by Cheapflights users on 11/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 12/255:00 pm -
2 stops7h 15m
Tue 12/295:30 am -
2 stops6h 40m
Deal found 11/3![United Airlines logo]()
$437
This United Airlines deal was found by Cheapflights users on 11/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 12/257:49 pm -
1 stop4h 26m
Fri 1/15:30 am -
2 stops7h 56m
Deal found 11/3![United Airlines logo]()
$460
This Delta deal was found by Cheapflights users on 11/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 11/204:00 pm -
1 stop5h 05m
Sun 11/225:40 am -
2 stops9h 43m
Deal found 11/3![Delta logo]()
$818
This United Airlines deal was found by Cheapflights users on 10/31. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 12/115:00 pm -
2 stops6h 59m
Sun 12/136:00 am -
1 stop7h 52m
Deal found 10/31![United Airlines logo]()
$528
Last-minute flights from Massachusetts to KnoxvilleDiscover last-minute flight deals from Massachusetts to Knoxville. Data last updated November 5, 2026 and is based on user searches.
Discover last-minute flight deals from Massachusetts to Knoxville. Data last updated November 5, 2026 and is based on user searches.
This American Airlines deal was found by Cheapflights users on 11/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 11/105:36 pm -
1 stop17h 40m
Fri 11/138:04 pm -
2 stops21h 03m
Deal found 11/2![American Airlines logo]()
$622
This Cheapflightsfares deal was found by Cheapflights users on 11/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Cheapflightsfares is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 11/1210:19 am -
Nonstop2h 30m
Sat 11/146:00 am -
Nonstop2h 19m
Deal found 11/1![Allegiant Air logo]()
$197
This Cheapflightsfares deal was found by Cheapflights users on 11/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Cheapflightsfares is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 11/149:09 am -
Nonstop2h 30m
Thu 11/196:30 am -
Nonstop2h 15m
Deal found 11/1![Allegiant Air logo]()
$141
This American Airlines deal was found by Cheapflights users on 11/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 11/175:36 pm -
1 stop17h 40m
Sat 11/2112:42 pm -
1 stop4h 39m
Deal found 11/2![American Airlines logo]()
$512
This American Airlines deal was found by Cheapflights users on 11/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 11/185:36 pm -
2 stops21h 45m
Sun 11/227:01 am -
2 stops10h 20m
Deal found 11/3![American Airlines logo]()
$538
This Delta deal was found by Cheapflights users on 11/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 11/194:00 pm -
1 stop5h 05m
Sun 11/225:40 am -
2 stops9h 43m
Deal found 11/3![Delta logo]()
$552
This American Airlines deal was found by Cheapflights users on 11/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 11/286:36 pm -
2 stops23h 07m
Sat 12/127:00 am -
1 stop11h 38m
Deal found 11/2![American Airlines logo]()
$449
This CheapOair deal was found by Cheapflights users on 11/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure CheapOair is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 12/311:35 am -
Nonstop2h 36m
Sun 12/68:30 am -
Nonstop2h 15m
Deal found 11/4![Allegiant Air logo]()
$205
This CheapOair deal was found by Cheapflights users on 10/31. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure CheapOair is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 12/1011:35 am -
Nonstop2h 36m
Sun 12/138:30 am -
Nonstop2h 15m
Deal found 10/31![Allegiant Air logo]()
$198
This Cheapflightsfares deal was found by Cheapflights users on 11/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Cheapflightsfares is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 12/179:31 am -
Nonstop2h 32m
Sun 12/206:30 am -
Nonstop2h 11m
Deal found 11/4![Allegiant Air logo]()
$163
This Cheapflightsfares deal was found by Cheapflights users on 11/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Cheapflightsfares is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 12/179:31 am -
Nonstop2h 32m
Thu 12/316:30 am -
Nonstop2h 11m
Deal found 11/1![Allegiant Air logo]()
$178
This Cheapflightsfares deal was found by Cheapflights users on 11/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Cheapflightsfares is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 12/209:31 am -
Nonstop2h 32m
Tue 12/226:15 am -
Nonstop2h 11m
Deal found 11/4![Allegiant Air logo]()
$193
One-way flights from Massachusetts to KnoxvilleSearch for one-way flight options from Massachusetts to Knoxville. Find affordable one-way fares based on user searches. Data last updated November 5, 2026.
Search for one-way flight options from Massachusetts to Knoxville. Find affordable one-way fares based on user searches. Data last updated November 5, 2026.
This Super.com deal was found by Cheapflights users on 11/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Super.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 11/149:09 am -
Nonstop2h 30m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 11/5![Allegiant Air logo]()
$69
This Kiwi.com deal was found by Cheapflights users on 11/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 1/29:21 am -
Nonstop2h 32m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 11/1![Allegiant Air logo]()
$83
This Kiwi.com deal was found by Cheapflights users on 11/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 12/179:31 am -
Nonstop2h 32m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 11/1![Allegiant Air logo]()
$85
This Kiwi.com deal was found by Cheapflights users on 10/31. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 12/611:35 am -
Nonstop2h 36m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 10/31![Allegiant Air logo]()
$92
This Kiwi.com deal was found by Cheapflights users on 11/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 1/39:31 am -
Nonstop2h 32m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 11/4![Allegiant Air logo]()
$97
This Cheapflightsfares deal was found by Cheapflights users on 11/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Cheapflightsfares is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 11/2612:35 pm -
Nonstop2h 33m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 11/4![Allegiant Air logo]()
$98
This Kiwi.com deal was found by Cheapflights users on 11/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 12/209:31 am -
Nonstop2h 32m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 11/3![Allegiant Air logo]()
$106
This Kiwi.com deal was found by Cheapflights users on 11/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 11/229:35 am -
Nonstop2h 33m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 11/3![Allegiant Air logo]()
$128
This Delta deal was found by Cheapflights users on 11/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 11/174:00 pm -
1 stop5h 05m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 11/5![Delta logo]()
$369
Find flight deals from Massachusetts to Knoxville
Keep the following information in mind while searching for Massachusetts to Knoxville flight deals. Data was last updated November 5, 2026.
Most accurate provider | FlightHub 3 stars |
|---|---|
Most trusted provider | FlightHub 3 stars |
Round-trip from | $141 (Cheapflightsfares) |
One-way from | $69 (Super.com) |
Popular in | January |
Cheapest in | February |
Average price | $380 |
Good round-trip deal | $179 or less |
Good one-way deal | $126 or less |
Cheapflights Fare Finder
Customize your flight search to find flights from Massachusetts to Knoxville that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 7,457,451 searches. Data last updated November 5, 2026.
Use the filters below to find and compare flights from Massachusetts to Knoxville that are best for you.
Fly from
Fly to
Route
Depart
Return
Cheapest round-trip
BostonKnoxville
BOS Boston Logan Intl - TYS Knoxville McGhee Tyson
BOSTYS
Boston Logan Intl
Sun 12/6
11:35 am-2:11 pm
Nonstop2h 36m
Knoxville McGhee Tyson
Wed 12/31
12:00 am-12:00 am
Nonstop0h 00m
$92
Quickest round-trip
BostonKnoxville
BOS Boston Logan Intl - TYS Knoxville McGhee Tyson
BOSTYS
Boston Logan Intl
Sun 1/3
9:31 am-12:03 pm
Nonstop2h 32m
Knoxville McGhee Tyson
Wed 12/31
12:00 am-12:00 am
Nonstop0h 00m
$111
BostonKnoxville
BOS Boston Logan Intl - TYS Knoxville McGhee Tyson
BOSTYS
Boston Logan Intl
Tue 12/29
7:49 pm-12:15 am
1 stop4h 26m
Knoxville McGhee Tyson
Wed 12/31
12:00 am-12:00 am
Nonstop0h 00m
$136
BostonKnoxville
BOS Boston Logan Intl - TYS Knoxville McGhee Tyson
BOSTYS
Boston Logan Intl
Fri 12/18
9:05 am-4:54 pm
1 stop7h 49m
Knoxville McGhee Tyson
Wed 12/31
12:00 am-12:00 am
Nonstop0h 00m
$136
BostonKnoxville
BOS Boston Logan Intl - TYS Knoxville McGhee Tyson
BOSTYS
Boston Logan Intl
Thu 11/26
5:20 pm-10:12 pm
1 stop4h 52m
Knoxville McGhee Tyson
Wed 12/31
12:00 am-12:00 am
Nonstop0h 00m
$136
BostonKnoxville
BOS Boston Logan Intl - TYS Knoxville McGhee Tyson
BOSTYS
Boston Logan Intl
Thu 12/17
4:00 pm-9:06 pm
1 stop5h 06m
Knoxville McGhee Tyson
Wed 12/31
12:00 am-12:00 am
Nonstop0h 00m
$136
BostonKnoxville
BOS Boston Logan Intl - TYS Knoxville McGhee Tyson
BOSTYS
Boston Logan Intl
Sun 11/22
6:00 am-10:44 am
1 stop4h 44m
Knoxville McGhee Tyson
Wed 12/31
12:00 am-12:00 am
Nonstop0h 00m
$160
BostonKnoxville
BOS Boston Logan Intl - TYS Knoxville McGhee Tyson
BOSTYS
Boston Logan Intl
Sat 1/2
5:00 pm-9:49 pm
1 stop4h 49m
Knoxville McGhee Tyson
Wed 12/31
12:00 am-12:00 am
Nonstop0h 00m
$183
BostonKnoxville
BOS Boston Logan Intl - TYS Knoxville McGhee Tyson
BOSTYS
Boston Logan Intl
Sun 12/6
5:35 am-3:00 pm
2 stops9h 25m
Knoxville McGhee Tyson
Wed 12/31
12:00 am-12:00 am
Nonstop0h 00m
$185
BostonKnoxville
BOS Boston Logan Intl - TYS Knoxville McGhee Tyson
BOSTYS
Boston Logan Intl
Sun 1/3
5:45 am-11:04 am
1 stop5h 19m
Knoxville McGhee Tyson
Wed 12/31
12:00 am-12:00 am
Nonstop0h 00m
$188
Showing 1-10 of 28 resultsSorted by cheapest first
Best time to book a flight from Massachusetts to Knoxville
Have a flexible travel schedule? Discover the best time to fly to Knoxville from Massachusetts with our price prediction graph.
BOS-TYS
ORH-TYS
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.
Cheapflights Insights
Everything you need to know about your flight from Massachusetts to Knoxville
USMA-TYS
BOS-TYS
ORH-TYS
What is the cheapest month to book a flight from Massachusetts to Knoxville?
Currently, February is the cheapest month in which you can book a flight from Massachusetts to Knoxville (average of $163). Flying from Massachusetts to Knoxville in January is currently the most expensive (average of $390). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.
What is the cheapest time of day to fly from MA to TYS?
Find hourly flight availability from Massachusetts to Knoxville. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated November 5, 2026.
When flying from Massachusetts to Knoxville, the time of day you decide to fly out makes little to no difference towards the overall price you’ll pay on tickets.
How much does it cost to fly round-trip from Massachusetts to Knoxville?
Airfare is below average for this route at the moment.
Massachusetts to Knoxville flights typically cost between $248 and $470 in November.The cheapest round-trip price found within the last 5 days was $141 on Allegiant Air (Nov 14-Nov 19).
How far ahead should I book a flight from Massachusetts to Knoxville?
To ensure you get the cheapest price possible for a flight from Massachusetts to Knoxville, you should look to book at least 76 days in advance of your intended travel date. The price of your flight may increase if you delay and leave booking until a week or so before departure.
Related info for your journey
Find useful and relevant information for your journey from Massachusetts to Knoxville. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.
Traveling to a place near Knoxville?
Book flights to Knoxville if you plan to visit one of these locationsCherokee
Morristown
Newport
Bryson City
Crossville
Murphy
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Alternative routes for Massachusetts to Knoxville
See prices for flight routes from nearby airports that may be better suited for you.
Complete your trip
Complete your trip to Knoxville by adding a car rental and/or hotel reservation to your travel itinerary.
Search flights from Massachusetts to Knoxville by cabin class
Find flights from Massachusetts to Knoxville, based on your preferred cabin class, be it economy, premium economy, business, or first class.
Other flights to Knoxville
Explore flights to Knoxville departing from other origins. Flights are based on user searches made on Cheapflights and were last updated on November 5, 2026.
Massachusetts and Knoxville flights
Browse other Massachusetts and Knoxville flight options. Last updated on November 5, 2026.
Popular flight searches
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Massachusetts to Knoxville flights
Consider these flights traveling from Massachusetts to Knoxville.
Top 5 airlines flying from Massachusetts to Knoxville
Discover the top 5 airlines that operate flights from Massachusetts to Knoxville. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 7,457,451 searches. Data last updated November 5, 2026.
| Airline | Cheapest | Average | Flexibility | On-time |
|---|---|---|---|---|
| Cheapest$92 | Average$236 | FlexibilityNo cancel fee | On-time88% | |
| Cheapest$138 | Average$354 | FlexibilityNo cancel fee | On-timeN/A | |
| Cheapest$210 | Average$384 | FlexibilityNo cancel fee | On-time69% | |
| Cheapest$262 | Average$455 | FlexibilityNo cancel fee | On-time71% | |
| Cheapest$279 | Average$393 | FlexibilityNo cancel fee | On-time63% |