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$428+ Cheap flights from Chile to Knoxville (TYS)

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 1/21. Fares are subject to change and may not be available on all flights or dates of travel.
SCL — TYS
Oct 17 — Oct 241
Fri 10/17
Fri 10/24
1 adult, Economy
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Cheap flight deals from Chile to Knoxville

Keep the following information in mind while searching for Chile to Knoxville flight deals. Data was last updated September 17, 2025.

Round-trip from

$696
(American Airlines)

One-way from

$428
(Kiwi.com)
From Chile to Knoxville McGhee Tyson
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One-way flight from Chile to Knoxville McGhee Tyson
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Find flight deals from Chile to Knoxville

Cheapest flights from Chile to Knoxville
Explore the most affordable flight options available from Chile to Knoxville. Find the lowest fares from popular airlines and budget airlines, with prices last updated on September 17, 2025.

This American Airlines deal was found by Cheapflights users on 9/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 10/209:55 pmSCL - TYS
1 stop26h 44mAmerican Airlines
Mon 10/272:21 pmTYS - SCL
1 stop16h 44mAmerican Airlines
Deal found 9/17$696
This Delta deal was found by Cheapflights users on 9/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 10/2912:20 amSCL - TYS
2 stops20h 50mDelta
Thu 11/610:05 amTYS - SCL
1 stop19h 35mDelta
Deal found 9/15$705
This LATAM Airlines deal was found by Cheapflights users on 9/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure LATAM Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 10/1912:10 amSCL - TYS
2 stops24h 36mLATAM Airlines
Mon 10/278:10 pmTYS - SCL
2 stops18h 20mLATAM Airlines
Deal found 9/17$716
This American Airlines deal was found by Cheapflights users on 9/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 10/219:55 pmSCL - TYS
1 stop26h 44mAmerican Airlines
Sun 10/266:00 amTYS - SCL
1 stop25h 05mAmerican Airlines
Deal found 9/16$737

Cheapflights Fare Finder

 
Customize your flight search to find flights from Chile to Knoxville that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated September 17, 2025.
Use the filters below to find and compare flights from Chile to Knoxville that are best for you.

Fly from

Chile

Fly to

Knoxville

Route

Depart

Return

Price

SantiagoKnoxville

SCL - TYS

SCLTYS

Santiago Arturo Merino Benitez

Mon 10/20

9:55 pm-11:39 pm

1 stop26h 44m

Knoxville McGhee Tyson

Mon 10/27

2:21 pm-8:05 am

1 stop16h 44m

$697

SantiagoKnoxville

SCL - TYS

SCLTYS

Santiago Arturo Merino Benitez

Thu 10/30

9:15 pm-4:11 pm

2 stops19h 56m

Knoxville McGhee Tyson

Thu 11/6

2:59 pm-9:00 am

2 stops16h 01m

$702

SantiagoKnoxville

SCL - TYS

SCLTYS

Santiago Arturo Merino Benitez

Wed 10/29

12:20 am-8:10 pm

2 stops20h 50m

Knoxville McGhee Tyson

Thu 11/6

10:05 am-7:40 am

1 stop19h 35m

$705

SantiagoKnoxville

SCL - TYS

SCLTYS

Santiago Arturo Merino Benitez

Mon 10/20

6:35 am-11:46 pm

2 stops18h 11m

Knoxville McGhee Tyson

Mon 10/27

8:15 am-11:05 am

3 stops25h 50m

$716

SantiagoKnoxville

SCL - TYS

SCLTYS

Santiago Arturo Merino Benitez

Wed 1/21

9:10 pm-12:05 pm

3 stops40h 55m

$428

SantiagoKnoxville

SCL - TYS

SCLTYS

Santiago Arturo Merino Benitez

Fri 1/16

9:29 pm-5:53 pm

3 stops46h 24m

$434

SantiagoKnoxville

SCL - TYS

SCLTYS

Santiago Arturo Merino Benitez

Sat 1/17

11:24 am-5:53 pm

3 stops32h 29m

$449

SantiagoKnoxville

SCL - TYS

SCLTYS

Santiago Arturo Merino Benitez

Mon 1/19

4:25 pm-3:57 pm

3 stops49h 32m

$473

SantiagoKnoxville

SCL - TYS

SCLTYS

Santiago Arturo Merino Benitez

Wed 1/21

11:15 pm-9:13 am

1 stop11h 58m

$552

SantiagoKnoxville

SCL - TYS

SCLTYS

Santiago Arturo Merino Benitez

Mon 1/19

10:35 am-11:44 pm

2 stops15h 09m

$552

Flights are sorted by cheapest round-trip flights first.

Deals found on 9/15

Showing 1-10 of 12 results
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Best time to book a flight from Chile to Knoxville

Have a flexible travel schedule? Discover the best time to fly to Knoxville from Chile with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Chile to Knoxville
No data available for this route at this time. Please check back soon.

Related info for your journey

Find useful and relevant information for your journey from Chile to Knoxville. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • What airport do you fly into for flights to Knoxville from Chile?

    For a flight from Chile to Knoxville, you will be flying into McGhee Tyson. Knoxville McGhee Tyson (TYS) is just 11.3 mi from the center of the city.

  • How long is the flight from Chile to Knoxville?

    There are many flights that can get you from Chile to Knoxville in 26h 44m. Fly via American Airlines to get the fastest option. There are 4853 mi between Chile and Knoxville.

  • Can I find deals for flights from Chile to Knoxville that include hotel bookings?

    Yes. In addition to deals on Chile to Knoxville flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Chile to Knoxville?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Chile to Knoxville.

  • Can I find deals for business class flights from Chile to Knoxville?

    Yes. Cheapflights offers flight deals from Chile to Knoxville by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Chile to Knoxville?

    Currently, January is the cheapest month in which you can book a flight from Chile to Knoxville (average of $295). Flying from Chile to Knoxville in March is currently the most expensive (average of $376). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

Traveling to a place near Knoxville?

Book flights to Knoxville if you plan to visit one of these locations
Morristown
Cherokee
Corbin
Alcoa
Oak Ridge
Murphy

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