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$714+ Cheap flights from Knoxville (TYS) to Chile

This is the cheapest round-trip flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 3/18. Fares are subject to change and may not be available on all flights or dates of travel.
TYS — SCL
Dec 6 — Dec 131
Sat 12/6
Sat 12/13
1 adult, Economy
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Cheap flight deals from Knoxville to Chile

Keep the following information in mind while searching for Knoxville to Chile flight deals. Data was last updated November 6, 2025.

Most accurate provider

FlightHub
3 stars

Most trusted provider

FlightHub
1 star

Round-trip from

$714
(Delta)
Provider with most accurate pricing for Knoxville McGhee Tyson-Santiago Arturo Merino Benitez flight deals.
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Provider most trusted by Cheapflights users for Knoxville McGhee Tyson-Santiago Arturo Merino Benitez flights.
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From Knoxville McGhee Tyson to Chile
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Find flight deals from Knoxville to Chile

Cheapest flights from Knoxville to Chile
Explore the most affordable flight options available from Knoxville to Chile. Find the lowest fares from popular airlines and budget airlines, with prices last updated on November 6, 2025.

This Mytrip deal was found by Cheapflights users on 11/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Mytrip is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 12/257:49 pmTYS - SCL
3 stops27h 20mMultiple Airlines
Wed 12/311:35 amSCL - TYS
2 stops19h 24mMultiple Airlines
Deal found 11/5$1,311
This American Airlines deal was found by Cheapflights users on 11/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 12/255:15 amTYS - SCL
1 stop26h 10mAmerican Airlines
Thu 1/111:15 pmSCL - TYS
1 stop14h 13mAmerican Airlines
Deal found 11/5$1,342
This United Airlines deal was found by Cheapflights users on 11/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 12/252:00 pmTYS - SCL
2 stops40h 50mUnited Airlines
Thu 1/110:45 pmSCL - TYS
2 stops20h 15mUnited Airlines
Deal found 11/5$1,497
This LATAM Airlines deal was found by Cheapflights users on 11/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure LATAM Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 12/254:54 pmTYS - SCL
2 stops19h 36mLATAM Airlines
Wed 12/3112:20 amSCL - TYS
2 stops21h 07mLATAM Airlines
Deal found 11/5$1,594

Cheapflights Fare Finder

 
Customize your flight search to find flights from Knoxville to Chile that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated November 6, 2025.
Use the filters below to find and compare flights from Knoxville to Chile that are best for you.

Fly from

Knoxville

Fly to

Chile

Route

Depart

Return

Price

KnoxvilleSantiago

TYS - SCL

TYSSCL

Knoxville McGhee Tyson

Wed 3/18

12:00 pm-7:00 am

1 stop18h 00m

Santiago Arturo Merino Benitez

Tue 3/31

10:35 pm-11:44 pm

2 stops26h 09m

$714

KnoxvilleSantiago

TYS - SCL

TYSSCL

Knoxville McGhee Tyson

Tue 3/24

5:00 pm-7:00 am

1 stop13h 00m

Santiago Arturo Merino Benitez

Tue 3/31

10:55 pm-8:36 pm

1 stop22h 41m

$714

KnoxvilleSantiago

TYS - SCL

TYSSCL

Knoxville McGhee Tyson

Sun 3/22

5:00 pm-5:55 am

1 stop35h 55m

Santiago Arturo Merino Benitez

Tue 3/31

10:55 pm-8:36 pm

1 stop22h 41m

$722

KnoxvilleSantiago

TYS - SCL

TYSSCL

Knoxville McGhee Tyson

Wed 3/18

12:00 pm-5:50 am

2 stops16h 50m

Santiago Arturo Merino Benitez

Wed 4/1

8:40 pm-9:13 am

1 stop13h 33m

$734

KnoxvilleSantiago

TYS - SCL

TYSSCL

Knoxville McGhee Tyson

Mon 3/23

12:00 pm-4:30 am

2 stops15h 30m

Santiago Arturo Merino Benitez

Wed 4/1

8:40 pm-9:13 am

1 stop13h 33m

$734

KnoxvilleSantiago

TYS - SCL

TYSSCL

Knoxville McGhee Tyson

Tue 3/24

5:00 pm-7:00 am

1 stop13h 00m

Santiago Arturo Merino Benitez

Mon 4/6

8:40 pm-9:13 am

1 stop12h 33m

$734

KnoxvilleSantiago

TYS - SCL

TYSSCL

Knoxville McGhee Tyson

Tue 3/24

5:00 pm-7:00 am

1 stop13h 00m

Santiago Arturo Merino Benitez

Wed 4/1

6:35 am-11:44 pm

2 stops18h 09m

$734

KnoxvilleSantiago

TYS - SCL

TYSSCL

Knoxville McGhee Tyson

Mon 3/23

2:30 pm-7:00 am

1 stop15h 30m

Santiago Arturo Merino Benitez

Thu 4/2

8:40 pm-9:13 am

1 stop13h 33m

$734

KnoxvilleSantiago

TYS - SCL

TYSSCL

Knoxville McGhee Tyson

Sun 3/22

5:00 pm-5:55 am

1 stop35h 55m

Santiago Arturo Merino Benitez

Wed 4/1

6:35 am-11:44 pm

2 stops18h 09m

$742

KnoxvilleSantiago

TYS - SCL

TYSSCL

Knoxville McGhee Tyson

Sun 3/22

5:00 pm-5:55 am

1 stop35h 55m

Santiago Arturo Merino Benitez

Thu 4/2

8:45 am-11:44 pm

2 stops15h 59m

$742

Flights are sorted by cheapest round-trip flights first.

Deals found on 11/6

Best time to book a flight from Knoxville to Chile

Have a flexible travel schedule? Discover the best time to fly to Chile from Knoxville with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Knoxville to Chile

What is the cheapest time of day to fly from TYS to CL?

Find hourly flight availability from Knoxville to Chile. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated November 6, 2025.

A simple way to save on the total cost of your ticket is to fly from Knoxville to Chile in the morning. If you’re flexible enough to do this you can expect to save up to 80% on your trip compared to booking a flight in the evening.

Reviews of airlines servicing Chile

Get insights into the airlines that provide service to Chile. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Chile. Reviews last updated November 6, 2025.
Get a feel of what it's like to fly with LATAM Airlines and American Airlines from Knoxville to Chile by reading reviews from past customers. Users have also rated airlines in terms of entertainment options, comfort, food, crew/service, and boarding process.
LATAM Airlines
7.5
Good
1,874 reviews

Entertainment

7.0

Food

6.7

Comfort

7.3

Crew

8.0

Boarding

7.6

Overall

7.5

Reviews

1 / 20
2.0
Mediocre

Anonymous,Oct 2025

MIA - GRU

Terrible baggage service! Almost lost my connection flight in SP
LATAM Airlines
7.5
Good
1,874 reviews
LATAM Airlines
7.5
Good
1,874 reviews

Entertainment

7.0

Food

6.7

Comfort

7.3

Crew

8.0

Boarding

7.6

Overall

7.5

Reviews

1 / 20
2.0
Mediocre

Anonymous,Oct 2025

MIA - GRU

Terrible baggage service! Almost lost my connection flight in SP
American Airlines
7.2
Good
11,041 reviews
LATAM Airlines
7.5
Good
1,874 reviews

Entertainment

7.0

Food

6.7

Comfort

7.3

Crew

8.0

Boarding

7.6

Overall

7.5

Reviews

1 / 20
2.0
Mediocre

Anonymous,Oct 2025

MIA - GRU

Terrible baggage service! Almost lost my connection flight in SP

Related info for your journey

Find useful and relevant information for your journey from Knoxville to Chile. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • What airport do you fly from for flights from Knoxville to Chile?

    Knoxville McGhee Tyson (TYS), located 11.3 mi from the city center, is the airport you fly out of when you book flights from Knoxville to Chile.

  • How long is the flight from Knoxville to Chile?

    Departing from Knoxville to Chile will take you 13h. Knoxville and Chile are separated by a distance of 4853 mi. Both multi-stop and nonstop flights can be found to your destination and back.

  • Can I find deals for flights from Knoxville to Chile that include hotel bookings?

    Yes. In addition to deals on Knoxville to Chile flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Knoxville to Chile?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Knoxville to Chile.

  • Can I find deals for business class flights from Knoxville to Chile?

    Yes. Cheapflights offers flight deals from Knoxville to Chile by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

See more FAQs

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Top 2 airlines flying from Knoxville to Chile

Discover the top 2 airlines that operate flights from Knoxville to Chile. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated November 6, 2025.
AirlineCheapestAverageFlexibilityOn-time
American AirlinesCheapest$678Average$931FlexibilityNo cancel feeOn-time71%
LATAM AirlinesCheapest$778Average$1,313FlexibilityNo cancel feeOn-time81%

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