$226+ Cheap flights from Charleston, WV to Knoxville (CRW - TYS)
This is the cheapest round-trip flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 9/20. Fares are subject to change and may not be available on all flights or dates of travel.
CRW — TYS
Oct 8 — Oct 151
Round-trip
1 adult, Economy
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Find cheap flights from Charleston to Knoxville with Cheapflights
1. Tell us where you want to go
Enter your travel information like dates, passengers, trip type (one-way or round trip), and preferred cabin class then click “Find deals”2. Select your favorite providers
We find the providers serving your travel needs. Choose up to four travel providers to compare side-by-side for flights, hotels, or car rentals.3. Compare prices and book
Review each provider’s pricing and select the best option for you! Book through your favorite provider’s website for a seamless experience.Cheap flight deals from Charleston to Knoxville
Cheapest
Best
Last-minute
One-way
Cheapest flights from Charleston to KnoxvilleExplore the most affordable flight options available from Charleston to Knoxville. Find the lowest fares from popular airlines and budget airlines, with prices last updated on September 8, 2026.
Explore the most affordable flight options available from Charleston to Knoxville. Find the lowest fares from popular airlines and budget airlines, with prices last updated on September 8, 2026.
This American Airlines deal was found by Cheapflights users on 9/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 10/34:09 pm -
1 stop4h 57m
Fri 10/97:58 pm -
1 stop4h 01m
Deal found 9/3![American Airlines logo]()
$366
This American Airlines deal was found by Cheapflights users on 9/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/24:24 pm -
1 stop4h 42m
Mon 10/57:58 pm -
1 stop4h 01m
Deal found 9/4![American Airlines logo]()
$437
This American Airlines deal was found by Cheapflights users on 9/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 9/224:24 pm -
1 stop6h 26m
Sat 9/266:15 am -
1 stop5h 50m
Deal found 9/6![American Airlines logo]()
$446
This American Airlines deal was found by Cheapflights users on 9/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 9/208:17 pm -
1 stop3h 34m
Thu 9/2412:09 pm -
1 stop6h 31m
Deal found 9/5![American Airlines logo]()
$634
This United Airlines deal was found by Cheapflights users on 9/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/26:05 pm -
2 stops27h 50m
Mon 10/57:25 pm -
2 stops14h 18m
Deal found 9/4![United Airlines logo]()
$776
This United Airlines deal was found by Cheapflights users on 9/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 9/186:05 pm -
2 stops27h 40m
Tue 9/226:00 am -
1 stop17h 59m
Deal found 9/3![United Airlines logo]()
$792
Best flights from Charleston to KnoxvilleDiscover carefully curated flight deals from Charleston to Knoxville that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated September 8, 2026.
Discover carefully curated flight deals from Charleston to Knoxville that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated September 8, 2026.
This American Airlines deal was found by Cheapflights users on 9/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/24:24 pm -
1 stop4h 42m
Mon 10/57:58 pm -
1 stop4h 01m
Deal found 9/4![American Airlines logo]()
$437
This United Airlines deal was found by Cheapflights users on 9/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/26:05 pm -
2 stops27h 50m
Mon 10/57:25 pm -
2 stops14h 18m
Deal found 9/4![United Airlines logo]()
$776
This American Airlines deal was found by Cheapflights users on 9/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 9/224:24 pm -
1 stop6h 26m
Sat 9/266:15 am -
1 stop5h 50m
Deal found 9/6![American Airlines logo]()
$446
This American Airlines deal was found by Cheapflights users on 9/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 10/34:57 pm -
2 stops5h 53m
Fri 10/97:58 pm -
1 stop4h 01m
Deal found 9/3![American Airlines logo]()
$491
This American Airlines deal was found by Cheapflights users on 9/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 9/208:17 pm -
1 stop3h 34m
Thu 9/2412:09 pm -
1 stop6h 31m
Deal found 9/5![American Airlines logo]()
$634
This United Airlines deal was found by Cheapflights users on 9/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 9/186:05 pm -
2 stops27h 40m
Tue 9/226:00 am -
1 stop17h 59m
Deal found 9/3![United Airlines logo]()
$792
This United Airlines deal was found by Cheapflights users on 9/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/97:03 am -
1 stop26h 42m
Sat 10/176:03 pm -
1 stop15h 40m
Deal found 9/3![United Airlines logo]()
$805
Last-minute flights from Charleston to KnoxvilleDiscover last-minute flight deals from Charleston to Knoxville. Data last updated September 8, 2026 and is based on user searches.
Discover last-minute flight deals from Charleston to Knoxville. Data last updated September 8, 2026 and is based on user searches.
This United Airlines deal was found by Cheapflights users on 9/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 9/186:05 pm -
2 stops27h 40m
Tue 9/226:00 am -
1 stop17h 59m
Deal found 9/3![United Airlines logo]()
$792
This American Airlines deal was found by Cheapflights users on 9/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 9/208:17 pm -
1 stop3h 34m
Thu 9/2412:09 pm -
1 stop6h 31m
Deal found 9/5![American Airlines logo]()
$634
This American Airlines deal was found by Cheapflights users on 9/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 9/224:24 pm -
1 stop6h 26m
Sat 9/266:15 am -
1 stop5h 50m
Deal found 9/6![American Airlines logo]()
$446
This American Airlines deal was found by Cheapflights users on 9/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/24:24 pm -
1 stop4h 42m
Mon 10/57:58 pm -
1 stop4h 01m
Deal found 9/4![American Airlines logo]()
$437
This United Airlines deal was found by Cheapflights users on 9/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/26:05 pm -
2 stops27h 50m
Mon 10/57:25 pm -
2 stops14h 18m
Deal found 9/4![United Airlines logo]()
$776
This American Airlines deal was found by Cheapflights users on 9/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 10/34:09 pm -
1 stop4h 57m
Fri 10/97:58 pm -
1 stop4h 01m
Deal found 9/3![American Airlines logo]()
$366
One-way flights from Charleston to KnoxvilleSearch for one-way flight options from Charleston to Knoxville. Find affordable one-way fares based on user searches. Data last updated September 8, 2026.
Search for one-way flight options from Charleston to Knoxville. Find affordable one-way fares based on user searches. Data last updated September 8, 2026.
This Kiwi.com deal was found by Cheapflights users on 9/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 9/202:43 pm -
1 stop29h 56m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 9/4![Multiple Airlines logo]()
$226
Find flight deals from Charleston to Knoxville
Discover tips and strategies to find the most affordable flight options for your journey from Charleston (CRW) to Knoxville (TYS). Learn about various techniques such as flexible date searches, comparing prices across and setting up price alerts. Use these methods to find the cheapest flights available for your travel needs. Data last updated September 8, 2026.
Most accurate provider | FlightHub 3 stars |
|---|---|
Most trusted provider | FlightHub 3 stars |
Round-trip from | $366 (American Airlines) |
One-way from | $226 (Kiwi.com) |
Cheapflights Fare Finder
Customize your flight search to find flights from Charleston to Knoxville that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 7,457,451 searches. Data last updated September 8, 2026.
Use the filters below to find and compare flights from Charleston to Knoxville that are best for you.
Fly from
Fly to
Route
Depart
Return
Cheapest round-trip
CharlestonKnoxville
CRW Charleston Yeager - TYS Knoxville McGhee Tyson
CRWTYS
Charleston Yeager
Sun 9/20
2:43 pm-7:34 pm
3 stops28h 51m
Knoxville McGhee Tyson
Wed 12/31
12:00 am-12:00 am
Nonstop0h 00m
$357
Quickest round-trip
CharlestonKnoxville
CRW Charleston Yeager - TYS Knoxville McGhee Tyson
CRWTYS
Charleston Yeager
Fri 10/2
4:24 pm-9:06 pm
1 stop4h 42m
Knoxville McGhee Tyson
Mon 10/5
7:58 pm-11:59 pm
1 stop4h 01m
$437
CharlestonKnoxville
CRW Charleston Yeager - TYS Knoxville McGhee Tyson
CRWTYS
Charleston Yeager
Tue 9/22
4:24 pm-10:50 pm
1 stop6h 26m
Knoxville McGhee Tyson
Sat 9/26
6:15 am-12:05 pm
1 stop5h 50m
$446
CharlestonKnoxville
CRW Charleston Yeager - TYS Knoxville McGhee Tyson
CRWTYS
Charleston Yeager
Sat 10/3
4:57 pm-10:50 pm
2 stops5h 53m
Knoxville McGhee Tyson
Fri 10/9
7:58 pm-11:59 pm
1 stop4h 01m
$491
CharlestonKnoxville
CRW Charleston Yeager - TYS Knoxville McGhee Tyson
CRWTYS
Charleston Yeager
Sun 9/20
8:17 pm-11:51 pm
1 stop3h 34m
Knoxville McGhee Tyson
Thu 9/24
12:09 pm-6:40 pm
1 stop6h 31m
$634
CharlestonKnoxville
CRW Charleston Yeager - TYS Knoxville McGhee Tyson
CRWTYS
Charleston Yeager
Fri 10/2
6:05 pm-9:55 pm
2 stops27h 50m
Knoxville McGhee Tyson
Mon 10/5
7:25 pm-9:43 am
2 stops14h 18m
$776
CharlestonKnoxville
CRW Charleston Yeager - TYS Knoxville McGhee Tyson
CRWTYS
Charleston Yeager
Fri 9/18
6:05 pm-9:45 pm
2 stops27h 40m
Knoxville McGhee Tyson
Tue 9/22
6:00 am-11:59 pm
1 stop17h 59m
$792
CharlestonKnoxville
CRW Charleston Yeager - TYS Knoxville McGhee Tyson
CRWTYS
Charleston Yeager
Fri 10/9
7:03 am-9:45 am
1 stop26h 42m
Knoxville McGhee Tyson
Sat 10/17
6:03 pm-9:43 am
1 stop15h 40m
$805
Sorted by cheapest first
Compare providers for flights from Charleston to Knoxville
Provider information is updated monthly. Please note that these providers often have deals for this flight, but the availability may vary on a day-by-day basis on Cheapflights.
Use the table below to compare price accuracy, trust ratings, and cancellation policies for each provider offering flight deals from Charleston to Knoxville in September.
| Provider | Price Accuracy | Trust Score* |
|---|---|---|
| Price Accuracy1 star | Trust Score*3 stars | |
| Price Accuracy3 stars | Trust Score*3 stars |
- Most accurate provider: When it comes to deals on Charleston, West Virginia-Knoxville flights, users find the pricing of FlightHub to be most consistent on Cheapflights vs. FlightHub Users can find the same prices on Charleston, West Virginia-Knoxville flight deals on Cheapflights vs. FlightHub >95% of the time. Price accuracy is based on data collected from Charleston, West Virginia-Knoxville flight searches over the past month and is updated monthly.
- Most trusted provider: When it comes to deals on Charleston, West Virginia-Knoxville flights, Cheapflights users trust FlightHub the most. FlightHub has received a user feedback score of 3 out of 3 stars (3 being the best), meaning they have been trusted the most by Cheapflights users looking for Charleston, West Virginia-Knoxville flight deals. Provider user feedback score is based on Cheapflights searches over the past month and is updated monthly.
Best time to book a flight from Charleston to Knoxville
Have a flexible travel schedule? Discover the best time to fly to Knoxville from Charleston with our price prediction graph.
CRW-TYS
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.
Related info for your journey
Find useful and relevant information for your journey from Charleston to Knoxville. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.
Traveling to a place near Knoxville?
Book flights to Knoxville if you plan to visit one of these locationsCherokee
Crossville
Morristown
Bryson City
Murphy
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