$146+ Cheap flights from San Diego (SAN) to Key Largo, FL
This is the cheapest round-trip flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 11/9. Fares are subject to change and may not be available on all flights or dates of travel.
SAN — MIA
Oct 11 — Oct 181
Round-trip
1 adult, Economy
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Find cheap flights from San Diego to Key Largo with Cheapflights
1. Tell us where you want to go
Enter your travel information like dates, passengers, trip type (one-way or round trip), and preferred cabin class then click “Find deals”2. Select your favorite providers
We find the providers serving your travel needs. Choose up to four travel providers to compare side-by-side for flights, hotels, or car rentals.3. Compare prices and book
Review each provider’s pricing and select the best option for you! Book through your favorite provider’s website for a seamless experience.Cheapflights Tip: The best prices from San Diego to Key Largo are usually found in October or January, booked 71 days in advance, depart on a Wednesday or Friday and return on a Wednesday
Cheap flight deals from San Diego to Key Largo
Cheapest
Best
Last-minute
One-way
Cheapest flights from San Diego to Key LargoExplore the most affordable flight options available from San Diego to Key Largo. Find the lowest fares from popular airlines and budget airlines, with prices last updated on September 11, 2026.
Explore the most affordable flight options available from San Diego to Key Largo. Find the lowest fares from popular airlines and budget airlines, with prices last updated on September 11, 2026.
This Kiwi.com deal was found by Cheapflights users on 9/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 9/144:54 pm -
1 stop28h 52m
Wed 9/235:50 am -
1 stop13h 09m
Deal found 9/8![Frontier logo]()
$297
This CheapOair deal was found by Cheapflights users on 9/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure CheapOair is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 10/176:25 am -
1 stop15h 22m
Sat 10/245:50 am -
1 stop21h 06m
Deal found 9/6![Frontier logo]()
$298
This Kiwi.com deal was found by Cheapflights users on 9/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 10/66:25 am -
2 stops11h 13m
Tue 10/135:50 am -
1 stop13h 08m
Deal found 9/7![Frontier logo]()
$299
This Kiwi.com deal was found by Cheapflights users on 9/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 9/226:25 am -
1 stop15h 21m
Sun 9/275:50 am -
1 stop21h 01m
Deal found 9/8![Frontier logo]()
$300
This Kiwi.com deal was found by Cheapflights users on 9/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/309:32 am -
1 stop9h 35m
Thu 11/125:15 am -
2 stops17h 32m
Deal found 9/8![Frontier logo]()
$301
This CheapOair deal was found by Cheapflights users on 9/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure CheapOair is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 11/114:53 pm -
1 stop28h 51m
Sun 11/155:50 am -
1 stop21h 07m
Deal found 9/9![Frontier logo]()
$302
This Frontier deal was found by Cheapflights users on 9/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Frontier is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 9/129:03 am -
1 stop9h 57m
Mon 9/145:50 am -
1 stop13h 08m
Deal found 9/6![Frontier logo]()
$303
This Kiwi.com deal was found by Cheapflights users on 9/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 9/216:25 am -
1 stop15h 21m
Sun 9/275:50 am -
1 stop21h 01m
Deal found 9/8![Frontier logo]()
$304
This Delta deal was found by Cheapflights users on 9/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 12/159:50 pm -
1 stop9h 37m
Fri 1/83:35 pm -
1 stop9h 06m
Deal found 9/9![Delta logo]()
$305
This Expedia deal was found by Cheapflights users on 9/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Expedia is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 10/66:25 am -
1 stop15h 21m
Mon 10/195:50 am -
1 stop21h 06m
Deal found 9/9![Frontier logo]()
$306
This CheapOair deal was found by Cheapflights users on 9/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure CheapOair is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 9/164:54 pm -
1 stop28h 52m
Sat 9/195:50 am -
1 stop13h 08m
Deal found 9/9![Frontier logo]()
$307
This Expedia deal was found by Cheapflights users on 9/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Expedia is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 9/96:25 am -
1 stop15h 21m
Thu 9/105:50 am -
1 stop13h 09m
Deal found 9/7![Frontier logo]()
$310
Best flights from San Diego to Key LargoDiscover carefully curated flight deals from San Diego to Key Largo that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated September 11, 2026.
Discover carefully curated flight deals from San Diego to Key Largo that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated September 11, 2026.
This Delta deal was found by Cheapflights users on 9/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 10/62:10 pm -
1 stop7h 43m
Mon 10/195:45 pm -
1 stop8h 39m
Deal found 9/10![Delta logo]()
$353
This United Airlines deal was found by Cheapflights users on 9/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/2910:30 pm -
1 stop9h 41m
Tue 11/39:15 am -
2 stops14h 09m
Deal found 9/10![United Airlines logo]()
$402
This Southwest deal was found by Cheapflights users on 9/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 1/16:15 am -
1 stop6h 15m
Mon 1/1112:20 pm -
1 stop9h 25m
Deal found 9/10![Southwest logo]()
$490
This Delta deal was found by Cheapflights users on 9/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 12/217:11 pm -
1 stop7h 12m
Tue 1/1211:45 am -
1 stop9h 57m
Deal found 9/9![Delta logo]()
$353
This United Airlines deal was found by Cheapflights users on 9/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 11/78:45 am -
1 stop10h 10m
Mon 11/166:24 am -
2 stops13h 53m
Deal found 9/8![United Airlines logo]()
$481
This Southwest deal was found by Cheapflights users on 9/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 2/63:55 pm -
2 stops17h 20m
Sun 2/146:40 am -
2 stops9h 15m
Deal found 9/7![Southwest logo]()
$494
This United Airlines deal was found by Cheapflights users on 9/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 11/48:45 am -
2 stops10h 14m
Tue 11/178:45 am -
2 stops11h 30m
Deal found 9/8![United Airlines logo]()
$486
This Southwest deal was found by Cheapflights users on 9/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 11/196:35 am -
2 stops10h 30m
Fri 11/275:05 am -
2 stops10h 25m
Deal found 9/5![Southwest logo]()
$495
This Southwest deal was found by Cheapflights users on 9/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 2/49:25 am -
2 stops9h 30m
Mon 2/81:40 pm -
2 stops10h 20m
Deal found 9/5![Southwest logo]()
$495
This United Airlines deal was found by Cheapflights users on 9/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 10/1712:04 pm -
1 stop7h 15m
Sat 10/248:02 am -
2 stops13h 33m
Deal found 9/5![United Airlines logo]()
$502
This United Airlines deal was found by Cheapflights users on 9/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 11/67:41 pm -
2 stops12h 30m
Mon 11/168:45 am -
1 stop10h 09m
Deal found 9/7![United Airlines logo]()
$502
Last-minute flights from San Diego to Key LargoDiscover last-minute flight deals from San Diego to Key Largo. Data last updated September 11, 2026 and is based on user searches.
Discover last-minute flight deals from San Diego to Key Largo. Data last updated September 11, 2026 and is based on user searches.
This Frontier deal was found by Cheapflights users on 9/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Frontier is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 9/129:03 am -
1 stop9h 57m
Mon 9/145:50 am -
1 stop13h 08m
Deal found 9/6![Frontier logo]()
$303
This Kiwi.com deal was found by Cheapflights users on 9/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 9/144:54 pm -
1 stop28h 52m
Wed 9/235:50 am -
1 stop13h 09m
Deal found 9/8![Frontier logo]()
$297
This CheapOair deal was found by Cheapflights users on 9/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure CheapOair is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 9/164:54 pm -
1 stop28h 52m
Sat 9/195:50 am -
1 stop13h 08m
Deal found 9/9![Frontier logo]()
$307
This Kiwi.com deal was found by Cheapflights users on 9/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 9/216:25 am -
1 stop15h 21m
Sun 9/275:50 am -
1 stop21h 01m
Deal found 9/8![Frontier logo]()
$304
This Kiwi.com deal was found by Cheapflights users on 9/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 9/226:25 am -
1 stop15h 21m
Sun 9/275:50 am -
1 stop21h 01m
Deal found 9/8![Frontier logo]()
$300
This Kiwi.com deal was found by Cheapflights users on 9/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 9/246:25 am -
1 stop15h 21m
Sun 9/275:50 am -
1 stop21h 01m
Deal found 9/8![Frontier logo]()
$311
This CheapOair deal was found by Cheapflights users on 9/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure CheapOair is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 9/306:25 am -
1 stop15h 21m
Sun 10/45:50 am -
1 stop21h 01m
Deal found 9/9![Frontier logo]()
$302
This Kiwi.com deal was found by Cheapflights users on 9/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 10/66:25 am -
2 stops11h 13m
Tue 10/135:50 am -
1 stop13h 08m
Deal found 9/7![Frontier logo]()
$299
This Expedia deal was found by Cheapflights users on 9/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Expedia is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 10/66:25 am -
1 stop15h 21m
Mon 10/195:50 am -
1 stop21h 06m
Deal found 9/9![Frontier logo]()
$306
This CheapOair deal was found by Cheapflights users on 9/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure CheapOair is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 10/176:25 am -
1 stop15h 22m
Sat 10/245:50 am -
1 stop21h 06m
Deal found 9/6![Frontier logo]()
$298
This Delta deal was found by Cheapflights users on 9/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 10/217:05 pm -
1 stop8h 17m
Fri 10/306:04 am -
1 stop9h 40m
Deal found 9/10![Delta logo]()
$305
This Kiwi.com deal was found by Cheapflights users on 9/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/309:32 am -
1 stop9h 35m
Thu 11/125:15 am -
2 stops17h 32m
Deal found 9/8![Frontier logo]()
$301
One-way flights from San Diego to Key LargoSearch for one-way flight options from San Diego to Key Largo. Find affordable one-way fares based on user searches. Data last updated September 11, 2026.
Search for one-way flight options from San Diego to Key Largo. Find affordable one-way fares based on user searches. Data last updated September 11, 2026.
This Kiwi.com deal was found by Cheapflights users on 9/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 11/98:32 pm -
2 stops21h 59m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 9/10![Frontier logo]()
$146
This Kiwi.com deal was found by Cheapflights users on 9/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 11/106:25 am -
2 stops12h 06m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 9/10![Frontier logo]()
$147
This Kiwi.com deal was found by Cheapflights users on 9/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 10/610:28 am -
2 stops21h 02m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 9/10![Frontier logo]()
$152
This Kiwi.com deal was found by Cheapflights users on 9/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/88:34 pm -
2 stops45h 55m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 9/8![Frontier logo]()
$153
This Kiwi.com deal was found by Cheapflights users on 9/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 10/510:28 am -
2 stops21h 02m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 9/6![Frontier logo]()
$154
This Kiwi.com deal was found by Cheapflights users on 9/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 10/31:38 pm -
2 stops32h 08m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 9/9![Frontier logo]()
$155
This Kiwi.com deal was found by Cheapflights users on 9/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 11/86:25 am -
1 stop15h 19m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 9/8![Frontier logo]()
$159
This Kiwi.com deal was found by Cheapflights users on 9/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/19:03 pm -
2 stops34h 27m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 9/8![Frontier logo]()
$161
This Frontier deal was found by Cheapflights users on 9/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Frontier is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 12/114:41 pm -
1 stop9h 38m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 9/9![Frontier logo]()
$162
This Kiwi.com deal was found by Cheapflights users on 9/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 10/103:14 pm -
2 stops16h 01m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 9/10![Frontier logo]()
$163
This Frontier deal was found by Cheapflights users on 9/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Frontier is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 10/76:25 am -
2 stops11h 13m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 9/7![Frontier logo]()
$164
Find flight deals from San Diego to Key Largo
Keep the following information in mind while searching for San Diego to Key Largo flight deals. Data was last updated September 11, 2026.
Most accurate provider | FlightHub 3 stars |
|---|---|
Most trusted provider | FlightHub 3 stars |
Round-trip from | $297 (Southwest) |
One-way from | $146 (Kiwi.com) |
Popular in | December |
Cheapest in | October |
Average price | $450 |
Cheapflights Fare Finder
Customize your flight search to find flights from San Diego to Key Largo that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 7,457,451 searches. Data last updated September 11, 2026.
Use the filters below to find and compare flights from San Diego to Key Largo that are best for you.
Fly from
Fly to
Route
Depart
Return
Cheapest round-trip
San DiegoMiami
SAN San Diego - MIA Miami
SANMIA
San Diego
Mon 10/12
10:40 pm-11:25 am
1 stop9h 45m
Miami
Wed 12/31
12:00 am-9:00 pm
Nonstop0h 00m
$173
Quickest round-trip
San DiegoMiami
SAN San Diego - MIA Miami
SANMIA
San Diego
Thu 12/17
7:10 pm-6:03 am
1 stop7h 53m
Miami
Wed 12/31
12:00 am-9:00 pm
Nonstop0h 00m
$194
San DiegoMiami
SAN San Diego - MIA Miami
SANMIA
San Diego
Fri 2/26
6:28 pm-7:47 am
1 stop10h 19m
Miami
Wed 12/31
12:00 am-9:00 pm
Nonstop0h 00m
$194
San DiegoMiami
SAN San Diego - MIA Miami
SANMIA
San Diego
Wed 3/3
1:35 pm-6:08 am
2 stops13h 33m
Miami
Wed 12/31
12:00 am-9:00 pm
Nonstop0h 00m
$227
San DiegoMiami
SAN San Diego - MIA Miami
SANMIA
San Diego
Tue 12/22
7:43 pm-7:51 am
1 stop9h 08m
Miami
Wed 12/31
12:00 am-9:00 pm
Nonstop0h 00m
$249
San DiegoMiami
SAN San Diego - MIA Miami
SANMIA
San Diego
Fri 12/25
6:23 pm-7:51 am
1 stop10h 28m
Miami
Wed 12/31
12:00 am-9:00 pm
Nonstop0h 00m
$249
San DiegoMiami
SAN San Diego - MIA Miami
SANMIA
San Diego
Sat 11/21
10:20 pm-12:09 pm
1 stop10h 49m
Miami
Wed 12/31
12:00 am-9:00 pm
Nonstop0h 00m
$249
San DiegoMiami
SAN San Diego - MIA Miami
SANMIA
San Diego
Sun 12/20
4:45 pm-6:03 am
2 stops10h 18m
Miami
Wed 12/31
12:00 am-9:00 pm
Nonstop0h 00m
$254
San DiegoMiami
SAN San Diego - MIA Miami
SANMIA
San Diego
Wed 11/11
8:45 am-9:59 pm
2 stops10h 14m
Miami
Wed 12/31
12:00 am-9:00 pm
Nonstop0h 00m
$254
San DiegoMiami
SAN San Diego - MIA Miami
SANMIA
San Diego
Mon 3/8
7:41 pm-5:35 pm
3 stops18h 54m
Miami
Wed 12/31
12:00 am-9:00 pm
Nonstop0h 00m
$259
Showing 1-10 of 21 resultsSorted by cheapest first
Best time to book a flight from San Diego to Key Largo
Have a flexible travel schedule? Discover the best time to fly to Key Largo from San Diego with our price prediction graph.
SAN-MIA
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.
Cheapflights Insights
Everything you need to know about your flight from San Diego to Key Largo
SAN-KE9
SAN-MIA
What is the cheapest time of day to fly from SAN to KE9?
Find hourly flight availability from San Diego to Key Largo. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated September 11, 2026.
It’s optimal to fly from San Diego to Key Largo in the afternoon. By choosing this option you can save up to 33% on the cost of your flight, compared to a flight at noon.
Weekly flight availability from San Diego to Key Largo
Explore weekly flight availability from San Diego to Key Largo. Discover flights operating on different days of the week, giving you the flexibility to choose a travel day that best fits your plans. Compare info to find the most convenient option for your journey. Data last updated September 11, 2026.
The most flights from SAN to KE9 are scheduled on a Monday (2 on average). You will have fewer flight options on Monday, which is when the least amount of flights are scheduled (2 on average).
How much does it cost to fly round-trip from San Diego to Key Largo?
Airfare is below average for this route at the moment.
San Diego to Key Largo flights typically cost between $373 and $514 in October.The cheapest round-trip price found within the last 5 days was $297 on Southwest (Oct 5-Oct 28).
What is the cheapest day to fly from San Diego to Key Largo?
Use this chart to determine the cheapest time to fly round-trip from San Diego to Key Largo. Price data was last updated on September 5, 2026.
Travelers seeking maximum savings on their San Diego to Key Largo flight should consider departing on Wednesday afternoons when fares are most often at their lowest. Saturday afternoons flights should be avoided if possible as fares are typically the most expensive at this time.
Reviews of airlines servicing Key Largo
Get insights into the airlines that provide service to Key Largo. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Key Largo. Reviews last updated September 11, 2026.
See what other customers who have flown with Southwest,Alaska Airlines, andDelta from San Diego to Key Largo have to say. You can also see how each airline compares in terms of entertainment options, comfort, food, crew/service, and boarding process.
Crew
8.6
Overall
8.0
Comfort
8.0
Food
7.0
Boarding
8.1
Entertainment
7.5
Reviews
1 / 20
6.0
GoodScott,Feb 2026
HOU - FLL
Crew
8.6
Overall
8.0
Comfort
8.0
Food
7.0
Boarding
8.1
Entertainment
7.5
Reviews
1 / 20
6.0
GoodScott,Feb 2026
HOU - FLL
Crew
8.6
Overall
8.0
Comfort
8.0
Food
7.0
Boarding
8.1
Entertainment
7.5
Reviews
1 / 20
6.0
GoodScott,Feb 2026
HOU - FLL
Crew
8.6
Overall
8.0
Comfort
8.0
Food
7.0
Boarding
8.1
Entertainment
7.5
Reviews
1 / 20
6.0
GoodScott,Feb 2026
HOU - FLL
Crew
8.6
Overall
8.0
Comfort
8.0
Food
7.0
Boarding
8.1
Entertainment
7.5
Reviews
1 / 20
6.0
GoodScott,Feb 2026
HOU - FLL
Crew
8.6
Overall
8.0
Comfort
8.0
Food
7.0
Boarding
8.1
Entertainment
7.5
Reviews
1 / 20
6.0
GoodScott,Feb 2026
HOU - FLL
Related info for your journey
Find useful and relevant information for your journey from San Diego to Key Largo. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.
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Top 7 airlines flying from San Diego to Key Largo
Discover the top 7 airlines that operate flights from San Diego to Key Largo. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 7,457,451 searches. Data last updated September 11, 2026.
| Airline | Cheapest | Average | Flexibility | On-time |
|---|---|---|---|---|
| Cheapest$165 | Average$272 | FlexibilityNo cancel fee | On-time62% | |
| Cheapest$183 | Average$329 | FlexibilityNo cancel fee | On-timeN/A | |
| Cheapest$212 | Average$528 | FlexibilityNo cancel fee | On-time75% | |
| Cheapest$214 | Average$463 | FlexibilityNo cancel fee | On-time63% | |
| Cheapest$222 | Average$456 | FlexibilityNo cancel fee | On-time71% | |
| Cheapest$227 | Average$331 | FlexibilityNo cancel fee | On-time62% | |
| Cheapest$238 | Average$379 | FlexibilityNo cancel fee | On-time69% |