$190+ Cheap flights from San Diego (SAN) to Key Largo, FL
This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 6/9. Fares are subject to change and may not be available on all flights or dates of travel.
SAN — MIA
Jun 12 — Jun 191
Round-trip
1 adult, Economy
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Find cheap flights from San Diego to Key Largo with Cheapflights
1. Tell us where you want to go
Enter your travel information like dates, passengers, trip type (one-way or round trip), and preferred cabin class then click “Find deals”2. Select your favorite providers
We find the providers serving your travel needs. Choose up to four travel providers to compare side-by-side for flights, hotels, or car rentals.3. Compare prices and book
Review each provider’s pricing and select the best option for you! Book through your favorite provider’s website for a seamless experience.Cheapflights Tip: The best prices from San Diego to Key Largo are usually found in January or October, booked 67 days in advance, depart on a Wednesday or Friday and return on a Wednesday
Cheap flight deals from San Diego to Key Largo
Cheapest
Best
Last-minute
One-way
Cheapest flights from San Diego to Key LargoExplore the most affordable flight options available from San Diego to Key Largo. Find the lowest fares from popular airlines and budget airlines, with prices last updated on May 13, 2026.
Explore the most affordable flight options available from San Diego to Key Largo. Find the lowest fares from popular airlines and budget airlines, with prices last updated on May 13, 2026.
This American Airlines deal was found by Cheapflights users on 5/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 8/2910:45 pm
SAN
- MIA
Nonstop5h 08m
American Airlines
Sat 9/58:45 pm
MIA
- SAN
Nonstop5h 19m
American Airlines
Deal found 5/12![American Airlines logo]()
$379
This Kiwi.com deal was found by Cheapflights users on 5/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 5/2610:07 pm
SAN
- MIA
1 stop29h 53m
Frontier
Tue 6/211:23 am
MIA
- SAN
2 stops24h 24m
Frontier
Deal found 5/9![Frontier logo]()
$380
This Trip.com deal was found by Cheapflights users on 5/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Trip.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 5/166:25 am
SAN
- MIA
1 stop20h 13m
Frontier
Wed 5/206:30 am
MIA
- SAN
1 stop20h 20m
Frontier
Deal found 5/8![Frontier logo]()
$381
This Kiwi.com deal was found by Cheapflights users on 5/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 7/66:25 am
SAN
- MIA
1 stop20h 26m
Frontier
Tue 7/1410:06 pm
MIA
- SAN
1 stop25h 52m
Frontier
Deal found 5/9![Frontier logo]()
$382
This Kiwi.com deal was found by Cheapflights users on 5/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 5/3112:09 pm
SAN
- MIA
1 stop19h 18m
Multiple Airlines
Sat 6/66:30 am
MIA
- SAN
1 stop20h 20m
Multiple Airlines
Deal found 5/8![Multiple Airlines logo]()
$383
This Kiwi.com deal was found by Cheapflights users on 5/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 5/291:38 pm
SAN
- MIA
2 stops51h 36m
Frontier
Sun 6/76:30 am
MIA
- SAN
1 stop29h 12m
Frontier
Deal found 5/8![Frontier logo]()
$384
This CheapOair deal was found by Cheapflights users on 5/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure CheapOair is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 5/196:25 am
SAN
- MIA
1 stop20h 13m
Frontier
Sun 5/246:30 am
MIA
- SAN
1 stop20h 20m
Frontier
Deal found 5/9![Frontier logo]()
$385
This Kiwi.com deal was found by Cheapflights users on 5/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 7/810:04 am
SAN
- MIA
1 stop16h 47m
Frontier
Fri 7/108:30 am
MIA
- SAN
2 stops18h 28m
Frontier
Deal found 5/11![Frontier logo]()
$386
This eDestinos deal was found by Cheapflights users on 5/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure eDestinos is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 6/58:15 pm
SAN
- MIA
1 stop30h 18m
Multiple Airlines
Sun 6/79:19 pm
MIA
- SAN
2 stops29h 31m
Multiple Airlines
Deal found 5/9![Multiple Airlines logo]()
$387
This Kiwi.com deal was found by Cheapflights users on 5/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 6/89:43 am
SAN
- MIA
2 stops30h 44m
Frontier
Tue 6/167:00 am
MIA
- SAN
1 stop14h 50m
Frontier
Deal found 5/9![Frontier logo]()
$388
This American Airlines deal was found by Cheapflights users on 5/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 8/298:00 am
SAN
- MIA
1 stop10h 05m
American Airlines
Wed 9/97:40 pm
MIA
- SAN
Nonstop5h 33m
American Airlines
Deal found 5/12![American Airlines logo]()
$389
This Expedia deal was found by Cheapflights users on 5/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Expedia is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 5/96:25 am
SAN
- MIA
1 stop20h 13m
Frontier
Sat 5/166:30 am
MIA
- SAN
1 stop29h 12m
Frontier
Deal found 5/8![Frontier logo]()
$390
Best flights from San Diego to Key LargoDiscover carefully curated flight deals from San Diego to Key Largo that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated May 13, 2026.
Discover carefully curated flight deals from San Diego to Key Largo that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated May 13, 2026.
This Delta deal was found by Cheapflights users on 5/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 6/86:15 am
SAN
- MIA
1 stop8h 49m
Delta
Wed 6/177:00 am
MIA
- SAN
1 stop8h 17m
Delta
Deal found 5/9![Delta logo]()
$442
This Southwest deal was found by Cheapflights users on 5/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 6/79:40 pm
SAN
- MIA
1 stop10h 20m
Southwest
Wed 6/175:45 am
MIA
- SAN
1 stop6h 45m
Southwest
Deal found 5/11![Southwest logo]()
$444
This Southwest deal was found by Cheapflights users on 5/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 7/39:45 am
SAN
- MIA
2 stops10h 30m
Southwest
Tue 7/75:45 am
MIA
- SAN
2 stops9h 30m
Southwest
Deal found 5/12![Southwest logo]()
$445
This Southwest deal was found by Cheapflights users on 5/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 6/298:00 am
SAN
- MIA
2 stops11h 35m
Southwest
Wed 7/16:35 am
MIA
- SAN
2 stops10h 40m
Southwest
Deal found 5/11![Southwest logo]()
$452
This Delta deal was found by Cheapflights users on 5/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 5/1910:49 am
SAN
- MIA
1 stop7h 29m
Delta
Sun 5/246:33 am
MIA
- SAN
1 stop9h 44m
Delta
Deal found 5/12![Delta logo]()
$519
This Southwest deal was found by Cheapflights users on 5/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 7/47:50 am
SAN
- MIA
1 stop8h 10m
Southwest
Sat 7/117:00 am
MIA
- SAN
2 stops15h 35m
Southwest
Deal found 5/11![Southwest logo]()
$455
This Delta deal was found by Cheapflights users on 5/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 5/226:45 pm
SAN
- MIA
1 stop9h 10m
Delta
Sat 5/235:57 pm
MIA
- SAN
1 stop8h 31m
Delta
Deal found 5/12![Delta logo]()
$519
This Southwest deal was found by Cheapflights users on 5/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 6/26:30 am
SAN
- MIA
2 stops8h 50m
Southwest
Fri 6/125:25 am
MIA
- SAN
2 stops8h 30m
Southwest
Deal found 5/8![Southwest logo]()
$473
This Southwest deal was found by Cheapflights users on 5/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 7/110:40 pm
SAN
- MIA
2 stops14h 45m
Southwest
Sun 7/55:50 am
MIA
- SAN
1 stop7h 15m
Southwest
Deal found 5/12![Southwest logo]()
$478
This Southwest deal was found by Cheapflights users on 5/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 6/611:30 am
SAN
- MIA
2 stops8h 10m
Southwest
Sat 6/137:00 am
MIA
- SAN
2 stops15h 35m
Southwest
Deal found 5/10![Southwest logo]()
$497
This Southwest deal was found by Cheapflights users on 5/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 5/2410:40 pm
SAN
- MIA
2 stops11h 30m
Southwest
Sat 5/306:15 am
MIA
- SAN
2 stops11h 30m
Southwest
Deal found 5/8![Southwest logo]()
$505
This Southwest deal was found by Cheapflights users on 5/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 6/36:20 am
SAN
- MIA
2 stops8h 10m
Southwest
Mon 6/85:10 am
MIA
- SAN
2 stops9h 30m
Southwest
Deal found 5/12![Southwest logo]()
$518
Last-minute flights from San Diego to Key LargoDiscover last-minute flight deals from San Diego to Key Largo. Data last updated May 13, 2026 and is based on user searches.
Discover last-minute flight deals from San Diego to Key Largo. Data last updated May 13, 2026 and is based on user searches.
This CheapOair deal was found by Cheapflights users on 5/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure CheapOair is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 5/149:37 am
SAN
- MIA
1 stop17h 01m
Frontier
Sun 5/176:30 am
MIA
- SAN
1 stop29h 12m
Frontier
Deal found 5/12![Frontier logo]()
$390
This Trip.com deal was found by Cheapflights users on 5/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Trip.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 5/166:25 am
SAN
- MIA
1 stop20h 13m
Frontier
Wed 5/206:30 am
MIA
- SAN
1 stop20h 20m
Frontier
Deal found 5/8![Frontier logo]()
$381
This CheapOair deal was found by Cheapflights users on 5/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure CheapOair is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 5/196:25 am
SAN
- MIA
1 stop20h 13m
Frontier
Sun 5/246:30 am
MIA
- SAN
1 stop20h 20m
Frontier
Deal found 5/9![Frontier logo]()
$385
This Kiwi.com deal was found by Cheapflights users on 5/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 5/2610:07 pm
SAN
- MIA
1 stop29h 53m
Frontier
Tue 6/211:23 am
MIA
- SAN
2 stops24h 24m
Frontier
Deal found 5/9![Frontier logo]()
$380
This Kiwi.com deal was found by Cheapflights users on 5/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 5/291:38 pm
SAN
- MIA
2 stops51h 36m
Frontier
Sun 6/76:30 am
MIA
- SAN
1 stop29h 12m
Frontier
Deal found 5/8![Frontier logo]()
$384
This Kiwi.com deal was found by Cheapflights users on 5/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 5/3112:09 pm
SAN
- MIA
1 stop19h 18m
Multiple Airlines
Sat 6/66:30 am
MIA
- SAN
1 stop20h 20m
Multiple Airlines
Deal found 5/8![Multiple Airlines logo]()
$383
This Kiwi.com deal was found by Cheapflights users on 5/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 6/16:25 am
SAN
- MIA
1 stop20h 08m
Frontier
Fri 6/128:30 am
MIA
- SAN
2 stops18h 45m
Frontier
Deal found 5/8![Frontier logo]()
$386
This eDestinos deal was found by Cheapflights users on 5/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure eDestinos is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 6/58:15 pm
SAN
- MIA
1 stop30h 18m
Multiple Airlines
Sun 6/79:19 pm
MIA
- SAN
2 stops29h 31m
Multiple Airlines
Deal found 5/9![Multiple Airlines logo]()
$387
This Kiwi.com deal was found by Cheapflights users on 5/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 6/66:25 am
SAN
- MIA
1 stop14h 02m
Frontier
Wed 6/1011:19 am
MIA
- SAN
2 stops15h 56m
Frontier
Deal found 5/10![Frontier logo]()
$391
This Kiwi.com deal was found by Cheapflights users on 5/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 6/89:43 am
SAN
- MIA
2 stops30h 44m
Frontier
Tue 6/167:00 am
MIA
- SAN
1 stop14h 50m
Frontier
Deal found 5/9![Frontier logo]()
$388
This American Airlines deal was found by Cheapflights users on 5/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 6/3010:26 pm
SAN
- MIA
Nonstop5h 10m
American Airlines
Tue 7/78:50 am
MIA
- SAN
Nonstop5h 22m
American Airlines
Deal found 5/12![American Airlines logo]()
$379
One-way flights from San Diego to Key LargoSearch for one-way flight options from San Diego to Key Largo. Find affordable one-way fares based on user searches. Data last updated May 13, 2026.
Search for one-way flight options from San Diego to Key Largo. Find affordable one-way fares based on user searches. Data last updated May 13, 2026.
This Kiwi.com deal was found by Cheapflights users on 5/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 6/912:54 pm
SAN
- MIA
1 stop28h 44m
Multiple Airlines
Deal found 5/12![Multiple Airlines logo]()
$190
This CheapOair deal was found by Cheapflights users on 5/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure CheapOair is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 5/176:25 am
SAN
- MIA
1 stop20h 13m
Frontier
Deal found 5/12![Frontier logo]()
$191
This Trip.com deal was found by Cheapflights users on 5/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Trip.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 5/2210:07 pm
SAN
- MIA
1 stop29h 53m
Frontier
Deal found 5/12![Frontier logo]()
$192
This Kiwi.com deal was found by Cheapflights users on 5/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 6/126:25 am
SAN
- MIA
2 stops38h 09m
Frontier
Deal found 5/11![Frontier logo]()
$194
This Kiwi.com deal was found by Cheapflights users on 5/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 6/46:25 am
SAN
- MIA
1 stop20h 08m
Frontier
Deal found 5/12![Frontier logo]()
$195
This Kiwi.com deal was found by Cheapflights users on 5/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 6/266:25 am
SAN
- MIA
2 stops35h 10m
Frontier
Deal found 5/11![Frontier logo]()
$196
This Kiwi.com deal was found by Cheapflights users on 5/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 5/304:17 pm
SAN
- MIA
2 stops48h 57m
Frontier
Deal found 5/9![Frontier logo]()
$199
This Southwest deal was found by Cheapflights users on 5/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 5/2410:40 pm
SAN
- MIA
1 stop10h 30m
Southwest
Deal found 5/12![Southwest logo]()
$200
This Kiwi.com deal was found by Cheapflights users on 5/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 5/2610:07 pm
SAN
- MIA
2 stops21h 40m
Frontier
Deal found 5/12![Frontier logo]()
$201
This Kiwi.com deal was found by Cheapflights users on 5/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 6/119:43 am
SAN
- MIA
2 stops35h 29m
Frontier
Deal found 5/12![Frontier logo]()
$203
Find flight deals from San Diego to Key Largo
Keep the following information in mind while searching for San Diego to Key Largo flight deals. Data was last updated May 13, 2026.
Most accurate provider | FlightHub 3 stars |
|---|---|
Most trusted provider | FlightHub 3 stars |
Round-trip from | $379 (American Airlines) |
One-way from | $190 (Kiwi.com) |
Popular in | December |
Cheapest in | January |
Average price | $445 |
Cheapflights Fare Finder
Customize your flight search to find flights from San Diego to Key Largo that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated May 13, 2026.
Use the filters below to find and compare flights from San Diego to Key Largo that are best for you.
Fly from
Fly to
Route
Depart
Return
Cheapest round-trip
San DiegoMiami
SAN - MIA
SANMIA
San Diego
Mon 6/8
6:15 am-6:04 pm
1 stop8h 49m
Miami
Wed 6/17
7:00 am-12:17 pm
1 stop8h 17m
$442
Quickest round-trip
San DiegoMiami
SAN - MIA
SANMIA
San Diego
Sun 6/7
9:40 pm-11:00 am
1 stop10h 20m
Miami
Wed 6/17
5:45 am-9:30 am
1 stop6h 45m
$444
San DiegoMiami
SAN - MIA
SANMIA
San Diego
Fri 7/3
9:45 am-11:15 pm
2 stops10h 30m
Miami
Tue 7/7
5:45 am-12:15 pm
2 stops9h 30m
$445
San DiegoMiami
SAN - MIA
SANMIA
San Diego
Mon 6/29
8:00 am-10:35 pm
2 stops11h 35m
Miami
Wed 7/1
6:35 am-2:15 pm
2 stops10h 40m
$452
San DiegoMiami
SAN - MIA
SANMIA
San Diego
Sat 7/4
7:50 am-7:00 pm
1 stop8h 10m
Miami
Sat 7/11
7:00 am-7:35 pm
2 stops15h 35m
$455
San DiegoMiami
SAN - MIA
SANMIA
San Diego
Tue 6/2
6:30 am-6:20 pm
2 stops8h 50m
Miami
Fri 6/12
5:25 am-10:55 am
2 stops8h 30m
$473
San DiegoMiami
SAN - MIA
SANMIA
San Diego
Wed 7/1
10:40 pm-4:25 pm
2 stops14h 45m
Miami
Sun 7/5
5:50 am-10:05 am
1 stop7h 15m
$478
San DiegoMiami
SAN - MIA
SANMIA
San Diego
Sat 6/6
11:30 am-10:40 pm
2 stops8h 10m
Miami
Sat 6/13
7:00 am-7:35 pm
2 stops15h 35m
$497
San DiegoMiami
SAN - MIA
SANMIA
San Diego
Sun 5/24
10:40 pm-1:10 pm
2 stops11h 30m
Miami
Sat 5/30
6:15 am-2:45 pm
2 stops11h 30m
$505
San DiegoMiami
SAN - MIA
SANMIA
San Diego
Wed 6/3
6:20 am-5:30 pm
2 stops8h 10m
Miami
Mon 6/8
5:10 am-11:40 am
2 stops9h 30m
$518
Showing 1-10 of 24 resultsSorted by cheapest first
Best time to book a flight from San Diego to Key Largo
Have a flexible travel schedule? Discover the best time to fly to Key Largo from San Diego with our price prediction graph.
SAN-MIA
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.
Cheapflights Insights
Everything you need to know about your flight from San Diego to Key Largo
SAN-KE9
SAN-MIA
What is the cheapest time of day to fly from SAN to KE9?
Find hourly flight availability from San Diego to Key Largo. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated May 13, 2026.
It’s optimal to fly from San Diego to Key Largo in the afternoon. By choosing this option you can save up to 32% on the cost of your flight, compared to a flight at noon.
What is the cheapest day to fly from San Diego to Key Largo?
Use this chart to determine the cheapest time to fly round-trip from San Diego to Key Largo. Price data was last updated on May 9, 2026.
Travelers seeking maximum savings on their San Diego to Key Largo flight should consider departing on Wednesday afternoons when fares are most often at their lowest. Saturday afternoons flights should be avoided if possible as fares are typically the most expensive at this time.
Weekly flight availability from San Diego to Key Largo
Explore weekly flight availability from San Diego to Key Largo. Discover flights operating on different days of the week, giving you the flexibility to choose a travel day that best fits your plans. Compare info to find the most convenient option for your journey. Data last updated May 13, 2026.
The most flights from SAN to KE9 are scheduled on a Monday (5 on average). You will have fewer flight options on Monday, which is when the least amount of flights are scheduled (5 on average).
How much does it cost to fly round-trip from San Diego to Key Largo?
Reviews of airlines servicing Key Largo
Get insights into the airlines that provide service to Key Largo. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Key Largo. Reviews last updated May 13, 2026.
See what other customers who have flown with Alaska Airlines,Southwest, andDelta from San Diego to Key Largo have to say. You can also see how each airline compares in terms of entertainment options, comfort, food, crew/service, and boarding process.
Entertainment
7.0
Boarding
8.1
Comfort
7.8
Overall
7.9
Crew
8.5
Food
7.0
Reviews
1 / 20
10.0
ExcellentFranzi,Mar 2026
SFO - PDX
Entertainment
7.0
Boarding
8.1
Comfort
7.8
Overall
7.9
Crew
8.5
Food
7.0
Reviews
1 / 20
10.0
ExcellentFranzi,Mar 2026
SFO - PDX
Entertainment
7.0
Boarding
8.1
Comfort
7.8
Overall
7.9
Crew
8.5
Food
7.0
Reviews
1 / 20
10.0
ExcellentFranzi,Mar 2026
SFO - PDX
Entertainment
7.0
Boarding
8.1
Comfort
7.8
Overall
7.9
Crew
8.5
Food
7.0
Reviews
1 / 20
10.0
ExcellentFranzi,Mar 2026
SFO - PDX
Entertainment
7.0
Boarding
8.1
Comfort
7.8
Overall
7.9
Crew
8.5
Food
7.0
Reviews
1 / 20
10.0
ExcellentFranzi,Mar 2026
SFO - PDX
Entertainment
7.0
Boarding
8.1
Comfort
7.8
Overall
7.9
Crew
8.5
Food
7.0
Reviews
1 / 20
10.0
ExcellentFranzi,Mar 2026
SFO - PDX
Related info for your journey
Find useful and relevant information for your journey from San Diego to Key Largo. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.
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Alternative routes for San Diego to Key Largo
See prices for flight routes from nearby airports that may be better suited for you.
Complete your trip
Complete your trip to Key Largo by adding a car rental and/or hotel reservation to your travel itinerary.
Search flights from San Diego to Key Largo by cabin class
Find flights from San Diego to Key Largo, based on your preferred cabin class, be it economy, premium economy, business, or first class.
San Diego and Key Largo flights
Browse other San Diego and Key Largo flight options. Last updated on May 13, 2026.
Other flights from San Diego
Browse through other flights departing from San Diego. Flights are based on user searches made on Cheapflights and were last updated on May 13, 2026.
Popular flight searches
Check out other popular destinations found by fellow travelers in 2026
San Diego to Key Largo flights
Consider these flights traveling from San Diego to Key Largo.
Top 9 airlines flying from San Diego to Key Largo
Discover the top 9 airlines that operate flights from San Diego to Key Largo. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated May 13, 2026.
| Airline | Cheapest | Average | Flexibility | On-time |
|---|---|---|---|---|
| Cheapest$86 | Average$236 | FlexibilityNo cancel fee | On-time62% | |
| Cheapest$90 | Average$214 | FlexibilityNo cancel fee | On-time65% | |
| Cheapest$180 | Average$438 | FlexibilityNo cancel fee | On-time71% | |
| Cheapest$183 | Average$425 | FlexibilityNo cancel fee | On-timeN/A | |
| Cheapest$199 | Average$298 | FlexibilityNo cancel fee | On-time85% | |
| Cheapest$214 | Average$452 | FlexibilityNo cancel fee | On-time63% | |
| Cheapest$217 | Average$501 | FlexibilityNo cancel fee | On-time75% | |
| Cheapest$227 | Average$355 | FlexibilityNo cancel fee | On-time62% | |
| Cheapest$238 | Average$382 | FlexibilityNo cancel fee | On-time69% |