$136+ Cheap flights from San Diego (SAN) to Key Largo, FL
This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 10/5. Fares are subject to change and may not be available on all flights or dates of travel.
SAN — MIA
Sep 9 — Sep 161
Round-trip
1 adult, Economy
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Find cheap flights from San Diego to Key Largo with Cheapflights
1. Tell us where you want to go
Enter your travel information like dates, passengers, trip type (one-way or round trip), and preferred cabin class then click “Find deals”2. Select your favorite providers
We find the providers serving your travel needs. Choose up to four travel providers to compare side-by-side for flights, hotels, or car rentals.3. Compare prices and book
Review each provider’s pricing and select the best option for you! Book through your favorite provider’s website for a seamless experience.Cheapflights Tip: The best prices from San Diego to Key Largo are usually found in October or January, booked 71 days in advance, depart on a Wednesday or Friday and return on a Wednesday
Cheap flight deals from San Diego to Key Largo
Cheapest
Best
Last-minute
One-way
Cheapest flights from San Diego to Key LargoExplore the most affordable flight options available from San Diego to Key Largo. Find the lowest fares from popular airlines and budget airlines, with prices last updated on August 10, 2026.
Explore the most affordable flight options available from San Diego to Key Largo. Find the lowest fares from popular airlines and budget airlines, with prices last updated on August 10, 2026.
This CheapOair deal was found by Cheapflights users on 8/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure CheapOair is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 11/26:25 am -
1 stop20h 23m
Tue 11/107:20 am -
1 stop19h 39m
Deal found 8/9![Frontier logo]()
$302
This Kiwi.com deal was found by Cheapflights users on 8/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 8/223:45 pm -
1 stop10h 07m
Tue 8/2511:10 am -
2 stops30h 40m
Deal found 8/8![Frontier logo]()
$303
This CheapOair deal was found by Cheapflights users on 8/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure CheapOair is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 8/296:25 am -
1 stop19h 27m
Sat 9/56:00 am -
1 stop30h 05m
Deal found 8/5![Frontier logo]()
$304
This Kiwi.com deal was found by Cheapflights users on 8/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 8/203:45 pm -
1 stop10h 07m
Fri 8/288:10 am -
2 stops33h 40m
Deal found 8/10![Frontier logo]()
$306
This Kiwi.com deal was found by Cheapflights users on 8/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 8/314:36 pm -
1 stop18h 36m
Mon 9/76:00 am -
1 stop30h 05m
Deal found 8/7![Frontier logo]()
$307
This Kiwi.com deal was found by Cheapflights users on 8/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 8/253:45 pm -
1 stop10h 07m
Wed 9/211:10 am -
2 stops25h 01m
Deal found 8/9![Frontier logo]()
$308
This Kiwi.com deal was found by Cheapflights users on 8/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 9/1310:28 am -
2 stops35h 18m
Thu 9/175:50 am -
1 stop13h 09m
Deal found 8/10![Frontier logo]()
$309
This Frontier deal was found by Cheapflights users on 8/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Frontier is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 8/273:45 pm -
1 stop10h 07m
Tue 9/16:50 am -
1 stop11h 51m
Deal found 8/9![Frontier logo]()
$310
This Kiwi.com deal was found by Cheapflights users on 8/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 9/226:25 am -
1 stop15h 21m
Fri 9/259:30 pm -
2 stops21h 28m
Deal found 8/5![Frontier logo]()
$311
This Kiwi.com deal was found by Cheapflights users on 8/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 11/66:25 am -
1 stop20h 23m
Tue 11/107:20 am -
1 stop19h 39m
Deal found 8/7![Frontier logo]()
$312
This Kiwi.com deal was found by Cheapflights users on 8/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 10/286:25 am -
1 stop20h 23m
Thu 11/58:00 am -
2 stops18h 59m
Deal found 8/7![Frontier logo]()
$313
This Kiwi.com deal was found by Cheapflights users on 8/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 9/206:45 pm -
1 stop24h 32m
Sat 9/265:50 am -
1 stop13h 08m
Deal found 8/8![Frontier logo]()
$314
Best flights from San Diego to Key LargoDiscover carefully curated flight deals from San Diego to Key Largo that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated August 10, 2026.
Discover carefully curated flight deals from San Diego to Key Largo that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated August 10, 2026.
This United Airlines deal was found by Cheapflights users on 8/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 1/198:00 am -
1 stop7h 05m
Fri 1/299:00 am -
1 stop9h 30m
Deal found 8/7![United Airlines logo]()
$362
This Delta deal was found by Cheapflights users on 8/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/229:45 pm -
1 stop8h 41m
Sat 10/316:00 am -
1 stop9h 08m
Deal found 8/9![Delta logo]()
$452
This Southwest deal was found by Cheapflights users on 8/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 11/106:30 am -
2 stops12h 40m
Wed 11/252:30 pm -
2 stops9h 55m
Deal found 8/6![Southwest logo]()
$460
This Southwest deal was found by Cheapflights users on 8/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 9/228:35 am -
2 stops10h 20m
Fri 9/255:45 am -
2 stops8h 30m
Deal found 8/5![Southwest logo]()
$462
This United Airlines deal was found by Cheapflights users on 8/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 11/810:30 pm -
1 stop9h 41m
Wed 11/119:00 am -
1 stop9h 12m
Deal found 8/7![United Airlines logo]()
$472
This United Airlines deal was found by Cheapflights users on 8/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 11/48:45 am -
2 stops10h 14m
Tue 11/179:00 am -
1 stop9h 12m
Deal found 8/7![United Airlines logo]()
$478
This Southwest deal was found by Cheapflights users on 8/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 12/177:40 am -
2 stops12h 25m
Tue 12/291:25 pm -
1 stop9h 45m
Deal found 8/8![Southwest logo]()
$493
This Southwest deal was found by Cheapflights users on 8/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 10/129:10 pm -
2 stops11h 15m
Mon 10/196:40 pm -
2 stops8h 30m
Deal found 8/8![Southwest logo]()
$505
This United Airlines deal was found by Cheapflights users on 8/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 9/196:15 am -
3 stops13h 19m
Wed 9/2311:30 am -
2 stops11h 32m
Deal found 8/9![United Airlines logo]()
$535
This Southwest deal was found by Cheapflights users on 8/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 1/810:10 am -
2 stops9h 05m
Sat 1/166:30 am -
2 stops14h 50m
Deal found 8/8![Southwest logo]()
$545
This United Airlines deal was found by Cheapflights users on 8/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 12/99:55 pm -
1 stop10h 16m
Tue 12/221:00 pm -
2 stops12h 49m
Deal found 8/5![United Airlines logo]()
$558
Last-minute flights from San Diego to Key LargoDiscover last-minute flight deals from San Diego to Key Largo. Data last updated August 10, 2026 and is based on user searches.
Discover last-minute flight deals from San Diego to Key Largo. Data last updated August 10, 2026 and is based on user searches.
This Kiwi.com deal was found by Cheapflights users on 8/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 8/1910:00 am -
2 stops15h 52m
Sat 8/226:00 am -
1 stop20h 51m
Deal found 8/5![Frontier logo]()
$312
This Kiwi.com deal was found by Cheapflights users on 8/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 8/203:45 pm -
1 stop10h 07m
Fri 8/288:10 am -
2 stops33h 40m
Deal found 8/10![Frontier logo]()
$306
This Kiwi.com deal was found by Cheapflights users on 8/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 8/223:45 pm -
1 stop10h 07m
Tue 8/2511:10 am -
2 stops30h 40m
Deal found 8/8![Frontier logo]()
$303
This Kiwi.com deal was found by Cheapflights users on 8/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 8/253:45 pm -
1 stop10h 07m
Wed 9/211:10 am -
2 stops25h 01m
Deal found 8/9![Frontier logo]()
$308
This Kiwi.com deal was found by Cheapflights users on 8/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 8/276:25 am -
2 stops14h 30m
Mon 8/316:00 am -
1 stop20h 51m
Deal found 8/6![Frontier logo]()
$302
This Frontier deal was found by Cheapflights users on 8/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Frontier is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 8/273:45 pm -
1 stop10h 07m
Tue 9/16:50 am -
1 stop11h 51m
Deal found 8/9![Frontier logo]()
$310
This CheapOair deal was found by Cheapflights users on 8/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure CheapOair is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 8/296:25 am -
1 stop19h 27m
Sat 9/56:00 am -
1 stop30h 05m
Deal found 8/5![Frontier logo]()
$304
This Kiwi.com deal was found by Cheapflights users on 8/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 8/314:36 pm -
1 stop18h 36m
Mon 9/76:00 am -
1 stop30h 05m
Deal found 8/7![Frontier logo]()
$307
This Kiwi.com deal was found by Cheapflights users on 8/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 9/106:25 am -
1 stop15h 21m
Sun 9/139:30 pm -
2 stops29h 21m
Deal found 8/6![Frontier logo]()
$313
This Kiwi.com deal was found by Cheapflights users on 8/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 9/1310:28 am -
2 stops35h 18m
Thu 9/175:50 am -
1 stop13h 09m
Deal found 8/10![Frontier logo]()
$309
This Kiwi.com deal was found by Cheapflights users on 8/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 9/206:45 pm -
1 stop24h 32m
Sat 9/265:50 am -
1 stop13h 08m
Deal found 8/8![Frontier logo]()
$314
This Kiwi.com deal was found by Cheapflights users on 8/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 9/226:25 am -
1 stop15h 21m
Fri 9/259:30 pm -
2 stops21h 28m
Deal found 8/5![Frontier logo]()
$311
One-way flights from San Diego to Key LargoSearch for one-way flight options from San Diego to Key Largo. Find affordable one-way fares based on user searches. Data last updated August 10, 2026.
Search for one-way flight options from San Diego to Key Largo. Find affordable one-way fares based on user searches. Data last updated August 10, 2026.
This Kiwi.com deal was found by Cheapflights users on 8/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 10/56:25 am -
2 stops25h 05m
Deal found 8/7![Frontier logo]()
$136
This Kiwi.com deal was found by Cheapflights users on 8/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 10/66:25 am -
2 stops25h 05m
Deal found 8/7![Frontier logo]()
$137
This Kiwi.com deal was found by Cheapflights users on 8/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 9/86:25 am -
2 stops19h 27m
Deal found 8/8![Frontier logo]()
$138
This Kiwi.com deal was found by Cheapflights users on 8/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 8/296:25 am -
2 stops11h 04m
Deal found 8/8![Frontier logo]()
$139
This Kiwi.com deal was found by Cheapflights users on 8/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 11/78:32 pm -
2 stops38h 47m
Deal found 8/9![Frontier logo]()
$140
This Kiwi.com deal was found by Cheapflights users on 8/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 11/118:32 pm -
2 stops38h 47m
Deal found 8/7![Frontier logo]()
$141
This Kiwi.com deal was found by Cheapflights users on 8/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 10/71:38 pm -
2 stops20h 35m
Deal found 8/7![Frontier logo]()
$142
This Kiwi.com deal was found by Cheapflights users on 8/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 9/210:00 am -
2 stops15h 52m
Deal found 8/6![Frontier logo]()
$143
This Kiwi.com deal was found by Cheapflights users on 8/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 9/184:54 pm -
2 stops24h 44m
Deal found 8/9![Frontier logo]()
$144
This Kiwi.com deal was found by Cheapflights users on 8/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 9/56:25 am -
2 stops11h 04m
Deal found 8/7![Frontier logo]()
$146
Find flight deals from San Diego to Key Largo
Keep the following information in mind while searching for San Diego to Key Largo flight deals. Data was last updated August 10, 2026.
Most accurate provider | FlightHub 3 stars |
|---|---|
Most trusted provider | FlightHub 3 stars |
Round-trip from | $302 (CheapOair) |
One-way from | $136 (Kiwi.com) |
Popular in | December |
Cheapest in | October |
Average price | $473 |
Cheapflights Fare Finder
Customize your flight search to find flights from San Diego to Key Largo that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated August 10, 2026.
Use the filters below to find and compare flights from San Diego to Key Largo that are best for you.
Fly from
Fly to
Route
Depart
Return
Cheapest round-trip
Quickest round-trip
San DiegoMiami
SAN San Diego - MIA Miami
SANMIA
San Diego
Tue 1/19
8:00 am-6:05 pm
1 stop7h 05m
Miami
Fri 1/29
9:00 am-3:30 pm
1 stop9h 30m
$362
San DiegoMiami
SAN San Diego - MIA Miami
SANMIA
San Diego
Thu 10/22
9:45 pm-9:26 am
1 stop8h 41m
Miami
Sat 10/31
6:00 am-12:08 pm
1 stop9h 08m
$452
San DiegoMiami
SAN San Diego - MIA Miami
SANMIA
San Diego
Tue 11/10
6:30 am-10:10 pm
2 stops12h 40m
Miami
Wed 11/25
2:30 pm-9:25 pm
2 stops9h 55m
$460
San DiegoMiami
SAN San Diego - MIA Miami
SANMIA
San Diego
Tue 9/22
8:35 am-9:55 pm
2 stops10h 20m
Miami
Fri 9/25
5:45 am-11:15 am
2 stops8h 30m
$462
San DiegoMiami
SAN San Diego - MIA Miami
SANMIA
San Diego
Sun 11/8
10:30 pm-11:11 am
1 stop9h 41m
Miami
Wed 11/11
9:00 am-3:12 pm
1 stop9h 12m
$472
San DiegoMiami
SAN San Diego - MIA Miami
SANMIA
San Diego
Wed 11/4
8:45 am-9:59 pm
2 stops10h 14m
Miami
Tue 11/17
9:00 am-3:12 pm
1 stop9h 12m
$478
San DiegoMiami
SAN San Diego - MIA Miami
SANMIA
San Diego
Thu 12/17
7:40 am-11:05 pm
2 stops12h 25m
Miami
Tue 12/29
1:25 pm-8:10 pm
1 stop9h 45m
$493
San DiegoMiami
SAN San Diego - MIA Miami
SANMIA
San Diego
Mon 10/12
9:10 pm-11:25 am
2 stops11h 15m
Miami
Mon 10/19
6:40 pm-12:10 am
2 stops8h 30m
$505
San DiegoMiami
SAN San Diego - MIA Miami
SANMIA
San Diego
Sat 9/19
6:15 am-10:34 pm
3 stops13h 19m
Miami
Wed 9/23
11:30 am-8:02 pm
2 stops11h 32m
$535
San DiegoMiami
SAN San Diego - MIA Miami
SANMIA
San Diego
Fri 1/8
10:10 am-10:15 pm
2 stops9h 05m
Miami
Sat 1/16
6:30 am-6:20 pm
2 stops14h 50m
$545
Showing 1-10 of 21 resultsSorted by cheapest first
Best time to book a flight from San Diego to Key Largo
Have a flexible travel schedule? Discover the best time to fly to Key Largo from San Diego with our price prediction graph.
SAN-MIA
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.
Cheapflights Insights
Everything you need to know about your flight from San Diego to Key Largo
SAN-KE9
SAN-MIA
What is the cheapest time of day to fly from SAN to KE9?
Find hourly flight availability from San Diego to Key Largo. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated August 10, 2026.
It’s optimal to fly from San Diego to Key Largo in the afternoon. By choosing this option you can save up to 32% on the cost of your flight, compared to a flight at noon.
Weekly flight availability from San Diego to Key Largo
Explore weekly flight availability from San Diego to Key Largo. Discover flights operating on different days of the week, giving you the flexibility to choose a travel day that best fits your plans. Compare info to find the most convenient option for your journey. Data last updated August 10, 2026.
The most flights from SAN to KE9 are scheduled on a Friday (6 on average). You will have fewer flight options on Monday, which is when the least amount of flights are scheduled (4 on average).
How much does it cost to fly round-trip from San Diego to Key Largo?
Airfare is below average for this route at the moment.
San Diego to Key Largo flights typically cost between $376 and $547 in November.The cheapest round-trip price found within the last 5 days was $302 on Frontier (Nov 2-Nov 10).
What is the cheapest day to fly from San Diego to Key Largo?
Use this chart to determine the cheapest time to fly round-trip from San Diego to Key Largo. Price data was last updated on August 8, 2026.
Travelers seeking maximum savings on their San Diego to Key Largo flight should consider departing on Wednesday afternoons when fares are most often at their lowest. Saturday afternoons flights should be avoided if possible as fares are typically the most expensive at this time.
Reviews of airlines servicing Key Largo
Get insights into the airlines that provide service to Key Largo. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Key Largo. Reviews last updated August 10, 2026.
See what other customers who have flown with Southwest,Alaska Airlines, andDelta from San Diego to Key Largo have to say. You can also see how each airline compares in terms of entertainment options, comfort, food, crew/service, and boarding process.
Entertainment
7.5
Overall
8.0
Crew
8.6
Boarding
8.1
Comfort
8.0
Food
7.0
Reviews
1 / 20
6.0
GoodScott,Feb 2026
HOU - FLL
Entertainment
7.5
Overall
8.0
Crew
8.6
Boarding
8.1
Comfort
8.0
Food
7.0
Reviews
1 / 20
6.0
GoodScott,Feb 2026
HOU - FLL
Entertainment
7.5
Overall
8.0
Crew
8.6
Boarding
8.1
Comfort
8.0
Food
7.0
Reviews
1 / 20
6.0
GoodScott,Feb 2026
HOU - FLL
Entertainment
7.5
Overall
8.0
Crew
8.6
Boarding
8.1
Comfort
8.0
Food
7.0
Reviews
1 / 20
6.0
GoodScott,Feb 2026
HOU - FLL
Entertainment
7.5
Overall
8.0
Crew
8.6
Boarding
8.1
Comfort
8.0
Food
7.0
Reviews
1 / 20
6.0
GoodScott,Feb 2026
HOU - FLL
Entertainment
7.5
Overall
8.0
Crew
8.6
Boarding
8.1
Comfort
8.0
Food
7.0
Reviews
1 / 20
6.0
GoodScott,Feb 2026
HOU - FLL
Related info for your journey
Find useful and relevant information for your journey from San Diego to Key Largo. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.
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San Diego and Key Largo flights
Browse other San Diego and Key Largo flight options. Last updated on August 10, 2026.
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Top 8 airlines flying from San Diego to Key Largo
Discover the top 8 airlines that operate flights from San Diego to Key Largo. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated August 10, 2026.
| Airline | Cheapest | Average | Flexibility | On-time |
|---|---|---|---|---|
| Cheapest$128 | Average$298 | FlexibilityNo cancel fee | On-time85% | |
| Cheapest$165 | Average$271 | FlexibilityNo cancel fee | On-time62% | |
| Cheapest$189 | Average$351 | FlexibilityNo cancel fee | On-timeN/A | |
| Cheapest$214 | Average$460 | FlexibilityNo cancel fee | On-time63% | |
| Cheapest$214 | Average$512 | FlexibilityNo cancel fee | On-time75% | |
| Cheapest$220 | Average$453 | FlexibilityNo cancel fee | On-time71% | |
| Cheapest$238 | Average$381 | FlexibilityNo cancel fee | On-time69% | |
| Cheapest$239 | Average$332 | FlexibilityNo cancel fee | On-time62% |