$133+ Cheap flights from San Diego (SAN) to Key Largo, FL
This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 8/25. Fares are subject to change and may not be available on all flights or dates of travel.
SAN — MIA
Jul 27 — Aug 31
Round-trip
1 adult, Economy
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Find cheap flights from San Diego to Key Largo with Cheapflights
1. Tell us where you want to go
Enter your travel information like dates, passengers, trip type (one-way or round trip), and preferred cabin class then click “Find deals”2. Select your favorite providers
We find the providers serving your travel needs. Choose up to four travel providers to compare side-by-side for flights, hotels, or car rentals.3. Compare prices and book
Review each provider’s pricing and select the best option for you! Book through your favorite provider’s website for a seamless experience.Cheapflights Tip: The best prices from San Diego to Key Largo are usually found in October or January, booked 82 days in advance, depart on a Wednesday or Friday and return on a Saturday
Cheap flight deals from San Diego to Key Largo
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Best
Last-minute
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Cheapest flights from San Diego to Key LargoExplore the most affordable flight options available from San Diego to Key Largo. Find the lowest fares from popular airlines and budget airlines, with prices last updated on June 27, 2026.
Explore the most affordable flight options available from San Diego to Key Largo. Find the lowest fares from popular airlines and budget airlines, with prices last updated on June 27, 2026.
This Kiwi.com deal was found by Cheapflights users on 6/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 8/38:51 pm
SAN
- MIA
2 stops24h 40m
Frontier
Fri 8/710:15 pm
MIA
- SAN
1 stop24h 51m
Frontier
Deal found 6/25![Frontier logo]()
$319
This Kiwi.com deal was found by Cheapflights users on 6/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 8/123:03 pm
SAN
- MIA
1 stop12h 27m
Frontier
Sun 8/1610:15 pm
MIA
- SAN
2 stops43h 35m
Frontier
Deal found 6/26![Frontier logo]()
$320
This Expedia deal was found by Cheapflights users on 6/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Expedia is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 7/83:03 pm
SAN
- MIA
1 stop12h 27m
Frontier
Wed 7/156:00 am
MIA
- SAN
1 stop30h 05m
Frontier
Deal found 6/25![Frontier logo]()
$322
This Trip.com deal was found by Cheapflights users on 6/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Trip.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 8/1310:10 am
SAN
- MIA
1 stop16h 41m
Frontier
Sun 8/1610:15 pm
MIA
- SAN
1 stop24h 51m
Frontier
Deal found 6/26![Frontier logo]()
$324
This Expedia deal was found by Cheapflights users on 6/24. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Expedia is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 7/306:25 am
SAN
- MIA
1 stop20h 26m
Frontier
Fri 8/76:00 am
MIA
- SAN
1 stop30h 10m
Frontier
Deal found 6/24![Frontier logo]()
$326
This United Airlines deal was found by Cheapflights users on 6/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 8/2512:01 pm
SAN
- MIA
1 stop7h 33m
United Airlines
Mon 8/3111:30 am
MIA
- SAN
2 stops11h 25m
United Airlines
Deal found 6/23![United Airlines logo]()
$327
This Kiwi.com deal was found by Cheapflights users on 6/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 7/153:03 pm
SAN
- MIA
1 stop12h 27m
Frontier
Mon 7/2010:15 pm
MIA
- SAN
2 stops20h 12m
Frontier
Deal found 6/23![Frontier logo]()
$328
This Kiwi.com deal was found by Cheapflights users on 6/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 8/610:10 am
SAN
- MIA
1 stop16h 41m
Frontier
Mon 8/1010:50 am
MIA
- SAN
2 stops16h 09m
Frontier
Deal found 6/26![Frontier logo]()
$329
This Kiwi.com deal was found by Cheapflights users on 6/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 8/410:00 am
SAN
- MIA
1 stop16h 51m
Frontier
Sun 8/910:15 pm
MIA
- SAN
1 stop24h 51m
Frontier
Deal found 6/23![Frontier logo]()
$331
This CheapOair deal was found by Cheapflights users on 6/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure CheapOair is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 7/73:03 pm
SAN
- MIA
1 stop12h 27m
Frontier
Sat 7/116:00 am
MIA
- SAN
1 stop20h 51m
Frontier
Deal found 6/26![Frontier logo]()
$332
This Expedia deal was found by Cheapflights users on 6/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Expedia is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 6/296:25 am
SAN
- MIA
1 stop20h 29m
Frontier
Fri 7/36:00 am
MIA
- SAN
1 stop29h 42m
Frontier
Deal found 6/22![Frontier logo]()
$333
This Expedia deal was found by Cheapflights users on 6/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Expedia is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 6/286:25 am
SAN
- MIA
1 stop20h 29m
Frontier
Sun 7/510:15 pm
MIA
- SAN
1 stop24h 51m
Frontier
Deal found 6/23![Frontier logo]()
$334
Best flights from San Diego to Key LargoDiscover carefully curated flight deals from San Diego to Key Largo that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated June 27, 2026.
Discover carefully curated flight deals from San Diego to Key Largo that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated June 27, 2026.
This United Airlines deal was found by Cheapflights users on 6/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 9/198:45 am
SAN
- MIA
2 stops10h 49m
United Airlines
Mon 9/214:41 pm
MIA
- SAN
1 stop10h 48m
United Airlines
Deal found 6/23![United Airlines logo]()
$331
This Delta deal was found by Cheapflights users on 6/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 12/28:00 am
SAN
- MIA
1 stop9h 54m
Delta
Sun 12/68:00 am
MIA
- SAN
1 stop9h 11m
Delta
Deal found 6/26![Delta logo]()
$379
This Southwest deal was found by Cheapflights users on 6/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 9/106:35 am
SAN
- MIA
1 stop11h 25m
Southwest
Mon 9/144:00 pm
MIA
- SAN
1 stop9h 00m
Southwest
Deal found 6/26![Southwest logo]()
$404
This United Airlines deal was found by Cheapflights users on 6/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 11/97:41 pm
SAN
- MIA
3 stops16h 00m
United Airlines
Thu 11/124:40 pm
MIA
- SAN
1 stop10h 39m
United Airlines
Deal found 6/23![United Airlines logo]()
$413
This Southwest deal was found by Cheapflights users on 6/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 8/155:30 pm
SAN
- MIA
2 stops15h 00m
Southwest
Sat 8/226:30 am
MIA
- SAN
2 stops12h 40m
Southwest
Deal found 6/26![Southwest logo]()
$425
This Southwest deal was found by Cheapflights users on 6/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 7/297:45 am
SAN
- MIA
2 stops11h 10m
Southwest
Wed 8/52:20 pm
MIA
- SAN
2 stops10h 40m
Southwest
Deal found 6/25![Southwest logo]()
$433
This United Airlines deal was found by Cheapflights users on 6/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 11/48:00 am
SAN
- MIA
1 stop7h 14m
United Airlines
Tue 11/178:58 am
MIA
- SAN
3 stops18h 21m
United Airlines
Deal found 6/22![United Airlines logo]()
$440
This Southwest deal was found by Cheapflights users on 6/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 10/186:40 am
SAN
- MIA
1 stop8h 40m
Southwest
Sat 10/246:40 am
MIA
- SAN
2 stops12h 10m
Southwest
Deal found 6/22![Southwest logo]()
$435
This Southwest deal was found by Cheapflights users on 6/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 9/138:55 pm
SAN
- MIA
2 stops11h 55m
Southwest
Sat 9/196:30 am
MIA
- SAN
2 stops10h 45m
Southwest
Deal found 6/25![Southwest logo]()
$440
This Southwest deal was found by Cheapflights users on 6/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 8/85:30 pm
SAN
- MIA
2 stops15h 05m
Southwest
Tue 8/112:20 pm
MIA
- SAN
2 stops10h 40m
Southwest
Deal found 6/26![Southwest logo]()
$443
This Southwest deal was found by Cheapflights users on 6/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 12/97:05 am
SAN
- MIA
1 stop9h 55m
Southwest
Sun 12/135:05 am
MIA
- SAN
2 stops10h 25m
Southwest
Deal found 6/25![Southwest logo]()
$447
Last-minute flights from San Diego to Key LargoDiscover last-minute flight deals from San Diego to Key Largo. Data last updated June 27, 2026 and is based on user searches.
Discover last-minute flight deals from San Diego to Key Largo. Data last updated June 27, 2026 and is based on user searches.
This Expedia deal was found by Cheapflights users on 6/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Expedia is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 6/286:25 am
SAN
- MIA
1 stop20h 29m
Frontier
Sun 7/510:15 pm
MIA
- SAN
1 stop24h 51m
Frontier
Deal found 6/23![Frontier logo]()
$334
This Expedia deal was found by Cheapflights users on 6/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Expedia is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 6/296:25 am
SAN
- MIA
1 stop20h 29m
Frontier
Fri 7/36:00 am
MIA
- SAN
1 stop29h 42m
Frontier
Deal found 6/22![Frontier logo]()
$333
This CheapOair deal was found by Cheapflights users on 6/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure CheapOair is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 7/73:03 pm
SAN
- MIA
1 stop12h 27m
Frontier
Sat 7/116:00 am
MIA
- SAN
1 stop20h 51m
Frontier
Deal found 6/26![Frontier logo]()
$332
This Expedia deal was found by Cheapflights users on 6/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Expedia is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 7/83:03 pm
SAN
- MIA
1 stop12h 27m
Frontier
Wed 7/156:00 am
MIA
- SAN
1 stop30h 05m
Frontier
Deal found 6/25![Frontier logo]()
$322
This Booking.com deal was found by Cheapflights users on 6/24. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Booking.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 7/83:03 pm
SAN
- MIA
1 stop12h 27m
Frontier
Sat 7/116:00 am
MIA
- SAN
1 stop20h 51m
Frontier
Deal found 6/24![Frontier logo]()
$331
This Kiwi.com deal was found by Cheapflights users on 6/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 7/153:03 pm
SAN
- MIA
1 stop12h 27m
Frontier
Mon 7/2010:15 pm
MIA
- SAN
2 stops20h 12m
Frontier
Deal found 6/23![Frontier logo]()
$328
This Kiwi.com deal was found by Cheapflights users on 6/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 7/208:51 pm
SAN
- MIA
1 stop30h 39m
Frontier
Sun 7/2610:15 pm
MIA
- SAN
1 stop24h 51m
Frontier
Deal found 6/25![Frontier logo]()
$339
This Kiwi.com deal was found by Cheapflights users on 6/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 7/278:51 pm
SAN
- MIA
2 stops24h 40m
Frontier
Fri 7/3110:15 pm
MIA
- SAN
1 stop24h 51m
Frontier
Deal found 6/25![Frontier logo]()
$340
This Kiwi.com deal was found by Cheapflights users on 6/24. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 7/284:12 pm
SAN
- MIA
2 stops10h 39m
Frontier
Fri 7/3110:15 pm
MIA
- SAN
1 stop24h 51m
Frontier
Deal found 6/24![Frontier logo]()
$338
This Southwest deal was found by Cheapflights users on 6/24. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 7/297:15 am
SAN
- MIA
1 stop11h 10m
Southwest
Wed 8/52:20 pm
MIA
- SAN
2 stops10h 40m
Southwest
Deal found 6/24![Southwest logo]()
$337
This Expedia deal was found by Cheapflights users on 6/24. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Expedia is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 7/306:25 am
SAN
- MIA
1 stop20h 26m
Frontier
Sun 8/96:00 am
MIA
- SAN
1 stop30h 10m
Frontier
Deal found 6/24![Frontier logo]()
$326
This CheapOair deal was found by Cheapflights users on 6/24. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure CheapOair is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 7/306:25 am
SAN
- MIA
1 stop20h 26m
Frontier
Mon 8/310:15 pm
MIA
- SAN
1 stop18h 53m
Frontier
Deal found 6/24![Frontier logo]()
$336
One-way flights from San Diego to Key LargoSearch for one-way flight options from San Diego to Key Largo. Find affordable one-way fares based on user searches. Data last updated June 27, 2026.
Search for one-way flight options from San Diego to Key Largo. Find affordable one-way fares based on user searches. Data last updated June 27, 2026.
This Delta deal was found by Cheapflights users on 6/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 7/222:18 pm
SAN
- MIA
1 stop7h 37m
Delta
Deal found 6/22![Delta logo]()
$133
This Frontier deal was found by Cheapflights users on 6/24. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Frontier is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 7/223:03 pm
SAN
- MIA
1 stop12h 27m
Frontier
Deal found 6/24![Frontier logo]()
$134
This Kiwi.com deal was found by Cheapflights users on 6/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 7/186:25 am
SAN
- MIA
1 stop19h 52m
Frontier
Deal found 6/23![Frontier logo]()
$135
This Expedia deal was found by Cheapflights users on 6/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Expedia is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 9/128:32 pm
SAN
- MIA
1 stop30h 16m
Frontier
Deal found 6/27![Frontier logo]()
$136
This American Airlines deal was found by Cheapflights users on 6/24. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 8/1312:32 pm
SAN
- MIA
Nonstop5h 22m
American Airlines
Deal found 6/24![American Airlines logo]()
$137
This United Airlines deal was found by Cheapflights users on 6/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 8/296:30 am
SAN
- MIA
2 stops13h 04m
United Airlines
Deal found 6/25![United Airlines logo]()
$138
This United Airlines deal was found by Cheapflights users on 6/24. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 8/2710:40 pm
SAN
- MIA
1 stop10h 14m
United Airlines
Deal found 6/24![United Airlines logo]()
$147
This United Airlines deal was found by Cheapflights users on 6/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 9/217:41 pm
SAN
- MIA
2 stops13h 13m
United Airlines
Deal found 6/23![United Airlines logo]()
$152
This Kiwi.com deal was found by Cheapflights users on 6/24. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 8/193:45 pm
SAN
- MIA
2 stops28h 20m
Frontier
Deal found 6/24![Frontier logo]()
$154
This Kiwi.com deal was found by Cheapflights users on 6/24. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 9/196:25 am
SAN
- MIA
2 stops26h 40m
Frontier
Deal found 6/24![Frontier logo]()
$159
This Kiwi.com deal was found by Cheapflights users on 6/24. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 7/204:12 pm
SAN
- MIA
2 stops29h 19m
Frontier
Deal found 6/24![Frontier logo]()
$160
Find flight deals from San Diego to Key Largo
Keep the following information in mind while searching for San Diego to Key Largo flight deals. Data was last updated June 27, 2026.
Most accurate provider | FlightHub 3 stars |
|---|---|
Most trusted provider | FlightHub 3 stars |
Round-trip from | $319 (Kiwi.com) |
One-way from | $133 (Delta) |
Popular in | June |
Cheapest in | October |
Average price | $546 |
Cheapflights Fare Finder
Customize your flight search to find flights from San Diego to Key Largo that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated June 27, 2026.
Use the filters below to find and compare flights from San Diego to Key Largo that are best for you.
Fly from
Fly to
Route
Depart
Return
Cheapest round-trip
San DiegoMiami
SAN - MIA
SANMIA
San Diego
Sat 9/19
8:45 am-10:34 pm
2 stops10h 49m
Miami
Mon 9/21
4:41 pm-12:29 am
1 stop10h 48m
$331
Quickest round-trip
San DiegoMiami
SAN - MIA
SANMIA
San Diego
Wed 12/2
8:00 am-8:54 pm
1 stop9h 54m
Miami
Sun 12/6
8:00 am-2:11 pm
1 stop9h 11m
$379
San DiegoMiami
SAN - MIA
SANMIA
San Diego
Thu 9/10
6:35 am-9:00 pm
1 stop11h 25m
Miami
Mon 9/14
4:00 pm-10:00 pm
1 stop9h 00m
$404
San DiegoMiami
SAN - MIA
SANMIA
San Diego
Mon 11/9
7:41 pm-2:41 pm
3 stops16h 00m
Miami
Thu 11/12
4:40 pm-12:19 am
1 stop10h 39m
$413
San DiegoMiami
SAN - MIA
SANMIA
San Diego
Sat 8/15
5:30 pm-11:30 am
2 stops15h 00m
Miami
Sat 8/22
6:30 am-4:10 pm
2 stops12h 40m
$425
San DiegoMiami
SAN - MIA
SANMIA
San Diego
Wed 7/29
7:45 am-9:55 pm
2 stops11h 10m
Miami
Wed 8/5
2:20 pm-10:00 pm
2 stops10h 40m
$433
San DiegoMiami
SAN - MIA
SANMIA
San Diego
Sun 10/18
6:40 am-6:20 pm
1 stop8h 40m
Miami
Sat 10/24
6:40 am-3:50 pm
2 stops12h 10m
$435
San DiegoMiami
SAN - MIA
SANMIA
San Diego
Wed 11/4
8:00 am-6:14 pm
1 stop7h 14m
Miami
Tue 11/17
8:58 am-12:19 am
3 stops18h 21m
$440
San DiegoMiami
SAN - MIA
SANMIA
San Diego
Sun 9/13
8:55 pm-11:50 am
2 stops11h 55m
Miami
Sat 9/19
6:30 am-2:15 pm
2 stops10h 45m
$440
San DiegoMiami
SAN - MIA
SANMIA
San Diego
Sat 8/8
5:30 pm-11:35 am
2 stops15h 05m
Miami
Tue 8/11
2:20 pm-10:00 pm
2 stops10h 40m
$443
Showing 1-10 of 22 resultsSorted by cheapest first
Best time to book a flight from San Diego to Key Largo
Have a flexible travel schedule? Discover the best time to fly to Key Largo from San Diego with our price prediction graph.
SAN-MIA
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.
Cheapflights Insights
Everything you need to know about your flight from San Diego to Key Largo
SAN-KE9
SAN-MIA
What is the cheapest time of day to fly from SAN to KE9?
Find hourly flight availability from San Diego to Key Largo. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated June 27, 2026.
It’s optimal to fly from San Diego to Key Largo in the afternoon. By choosing this option you can save up to 32% on the cost of your flight, compared to a flight at noon.
How much does it cost to fly round-trip from San Diego to Key Largo?
What is the cheapest day to fly from San Diego to Key Largo?
Use this chart to determine the cheapest time to fly round-trip from San Diego to Key Largo. Price data was last updated on June 20, 2026.
Travelers seeking maximum savings on their San Diego to Key Largo flight should consider departing on Wednesday afternoons when fares are most often at their lowest. Saturday afternoons flights should be avoided if possible as fares are typically the most expensive at this time.
Reviews of airlines servicing Key Largo
Get insights into the airlines that provide service to Key Largo. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Key Largo. Reviews last updated June 27, 2026.
See what other customers who have flown with Alaska Airlines,Southwest, andDelta from San Diego to Key Largo have to say. You can also see how each airline compares in terms of entertainment options, comfort, food, crew/service, and boarding process.
Boarding
8.1
Food
7.0
Entertainment
7.0
Overall
7.9
Comfort
7.8
Crew
8.5
Reviews
1 / 20
2.0
MediocreArt,Dec 2025
SAN - OGG
Boarding
8.1
Food
7.0
Entertainment
7.0
Overall
7.9
Comfort
7.8
Crew
8.5
Reviews
1 / 20
2.0
MediocreArt,Dec 2025
SAN - OGG
Boarding
8.1
Food
7.0
Entertainment
7.0
Overall
7.9
Comfort
7.8
Crew
8.5
Reviews
1 / 20
2.0
MediocreArt,Dec 2025
SAN - OGG
Boarding
8.1
Food
7.0
Entertainment
7.0
Overall
7.9
Comfort
7.8
Crew
8.5
Reviews
1 / 20
2.0
MediocreArt,Dec 2025
SAN - OGG
Boarding
8.1
Food
7.0
Entertainment
7.0
Overall
7.9
Comfort
7.8
Crew
8.5
Reviews
1 / 20
2.0
MediocreArt,Dec 2025
SAN - OGG
Boarding
8.1
Food
7.0
Entertainment
7.0
Overall
7.9
Comfort
7.8
Crew
8.5
Reviews
1 / 20
2.0
MediocreArt,Dec 2025
SAN - OGG
Related info for your journey
Find useful and relevant information for your journey from San Diego to Key Largo. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.
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Alternative routes for San Diego to Key Largo
See prices for flight routes from nearby airports that may be better suited for you.
Complete your trip
Complete your trip to Key Largo by adding a car rental and/or hotel reservation to your travel itinerary.
Search flights from San Diego to Key Largo by cabin class
Find flights from San Diego to Key Largo, based on your preferred cabin class, be it economy, premium economy, business, or first class.
San Diego and Key Largo flights
Browse other San Diego and Key Largo flight options. Last updated on June 27, 2026.
Other flights from San Diego
Browse through other flights departing from San Diego. Flights are based on user searches made on Cheapflights and were last updated on June 27, 2026.
Popular flight searches
Check out other popular destinations found by fellow travelers in 2026
San Diego to Key Largo flights
Consider these flights traveling from San Diego to Key Largo.
Top 8 airlines flying from San Diego to Key Largo
Discover the top 8 airlines that operate flights from San Diego to Key Largo. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated June 27, 2026.
| Airline | Cheapest | Average | Flexibility | On-time |
|---|---|---|---|---|
| Cheapest$86 | Average$231 | FlexibilityNo cancel fee | On-time62% | |
| Cheapest$128 | Average$298 | FlexibilityNo cancel fee | On-time85% | |
| Cheapest$171 | Average$362 | FlexibilityNo cancel fee | On-timeN/A | |
| Cheapest$180 | Average$437 | FlexibilityNo cancel fee | On-time71% | |
| Cheapest$198 | Average$454 | FlexibilityNo cancel fee | On-time63% | |
| Cheapest$217 | Average$512 | FlexibilityNo cancel fee | On-time75% | |
| Cheapest$238 | Average$379 | FlexibilityNo cancel fee | On-time69% | |
| Cheapest$239 | Average$332 | FlexibilityNo cancel fee | On-time62% |