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Key Largo

$140+ Cheap flights from San Diego (SAN) to Key Largo, FL

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 3/12. Fares are subject to change and may not be available on all flights or dates of travel.
SAN — MIA
Jan 17 — Jan 241
Sat 1/17
Sat 1/24
1 adult, Economy
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Cheapflights Tip: The best prices from San Diego to Key Largo are usually found in January or October, booked 86 days in advance, depart on a Friday or Saturday and return on a Wednesday

Cheap flight deals from San Diego to Key Largo

Cheapest flights from San Diego to Key Largo
Explore the most affordable flight options available from San Diego to Key Largo. Find the lowest fares from popular airlines and budget airlines, with prices last updated on December 18, 2025.

This Kiwi.com deal was found by Cheapflights users on 12/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 12/309:14 pmSAN - MIA
2 stops28h 46mFrontier
Sun 1/115:21 pmMIA - SAN
1 stop9h 28mFrontier
Deal found 12/17$262
This eDestinos deal was found by Cheapflights users on 12/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure eDestinos is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 12/301:06 pmSAN - MIA
2 stops36h 54mFrontier
Tue 1/66:16 pmMIA - SAN
2 stops30h 41mFrontier
Deal found 12/17$263
This CheapOair deal was found by Cheapflights users on 12/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure CheapOair is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 12/211:06 pmSAN - MIA
1 stop13h 29mFrontier
Tue 12/237:05 amMIA - SAN
1 stop8h 06mFrontier
Deal found 12/16$268
This Kiwi.com deal was found by Cheapflights users on 12/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 12/292:10 pmSAN - MIA
2 stops43h 28mMultiple Airlines
Sun 1/119:26 pmMIA - SAN
1 stop29h 10mMultiple Airlines
Deal found 12/16$278
This Frontier deal was found by Cheapflights users on 12/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Frontier is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 12/244:47 pmSAN - MIA
1 stop9h 13mFrontier
Wed 12/317:05 amMIA - SAN
1 stop8h 06mFrontier
Deal found 12/16$281
This eDestinos deal was found by Cheapflights users on 12/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure eDestinos is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 12/309:14 pmSAN - MIA
3 stops45h 41mMultiple Airlines
Tue 1/66:16 pmMIA - SAN
2 stops24h 53mMultiple Airlines
Deal found 12/16$303
This Frontier deal was found by Cheapflights users on 12/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Frontier is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 12/241:06 pmSAN - MIA
1 stop13h 29mFrontier
Thu 1/17:05 amMIA - SAN
1 stop8h 06mFrontier
Deal found 12/16$304
This CheapOair deal was found by Cheapflights users on 12/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure CheapOair is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 12/241:06 pmSAN - MIA
1 stop13h 29mFrontier
Mon 12/297:05 amMIA - SAN
1 stop8h 33mFrontier
Deal found 12/16$313
This CheapOair deal was found by Cheapflights users on 12/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure CheapOair is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 12/211:06 pmSAN - MIA
1 stop13h 29mFrontier
Wed 12/314:30 pmMIA - SAN
1 stop8h 35mFrontier
Deal found 12/16$316
This American Airlines deal was found by Cheapflights users on 12/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 12/1610:35 pmSAN - MIA
Nonstop4h 48mAmerican Airlines
Tue 2/108:11 pmMIA - SAN
Nonstop5h 58mAmerican Airlines
Deal found 12/16$318

Find flight deals from San Diego to Key Largo

Keep the following information in mind while searching for San Diego to Key Largo flight deals. Data was last updated December 18, 2025.

Most accurate provider

CheapOair
3 stars

Most trusted provider

CheapOair
3 stars

Round-trip from

$261
(Kiwi.com)

One-way from

$140
(Kiwi.com)

Popular in

December

Cheapest in

January

Average price

$529
Provider with most accurate pricing for San Diego-Miami flight deals.
Search Deals
Provider most trusted by Cheapflights users for San Diego-Miami flights.
Search Deals
From San Diego to Key Largo
Search Deals
One-way flight from San Diego to Key Largo
Search Deals
Highest demand for flights based on searches. 4% potential increase in price ($19 potential increase over avg. RT price).
Search Deals
Cheapest flight prices on average. 1% potential price decrease ($8 potential savings vs. average RT price).
Search Deals
Average for round-trip flights in December 2025
Search Deals

Cheapflights Fare Finder

 
Customize your flight search to find flights from San Diego to Key Largo that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated December 18, 2025.
Use the filters below to find and compare flights from San Diego to Key Largo that are best for you.

Fly from

San Diego

Fly to

Key Largo

Route

Depart

Return

Price

San DiegoMiami

SAN - MIA

SANMIA

San Diego

Sun 1/11

10:30 am-8:20 pm

1 stop6h 50m

Miami

Tue 1/13

12:55 pm-8:50 pm

2 stops10h 55m

$262

San DiegoMiami

SAN - MIA

SANMIA

San Diego

Fri 2/20

5:00 pm-12:40 pm

2 stops16h 40m

Miami

Sat 2/28

7:15 am-1:05 pm

1 stop8h 50m

$295

San DiegoMiami

SAN - MIA

SANMIA

San Diego

Wed 1/28

11:08 am-11:30 pm

2 stops9h 22m

Miami

Mon 2/2

4:51 pm-11:42 pm

2 stops9h 51m

$321

San DiegoMiami

SAN - MIA

SANMIA

San Diego

Wed 2/18

5:00 pm-12:40 pm

2 stops16h 40m

Miami

Tue 2/24

3:20 pm-10:50 pm

1 stop10h 30m

$335

San DiegoMiami

SAN - MIA

SANMIA

San Diego

Tue 12/30

10:30 pm-9:28 am

1 stop7h 58m

Miami

Tue 1/13

8:00 am-3:40 pm

1 stop10h 40m

$358

San DiegoMiami

SAN - MIA

SANMIA

San Diego

Tue 12/30

10:20 pm-10:36 am

1 stop9h 16m

Miami

Wed 1/14

8:00 am-3:40 pm

1 stop10h 40m

$358

San DiegoMiami

SAN - MIA

SANMIA

San Diego

Sat 2/21

6:15 am-6:16 pm

2 stops9h 01m

Miami

Tue 2/24

8:45 am-5:39 pm

2 stops11h 54m

$367

San DiegoMiami

SAN - MIA

SANMIA

San Diego

Mon 12/29

2:05 pm-12:05 am

1 stop7h 00m

Miami

Tue 1/13

9:00 am-2:50 pm

1 stop8h 50m

$374

San DiegoMiami

SAN - MIA

SANMIA

San Diego

Sun 12/28

4:15 pm-5:00 am

1 stop9h 45m

Miami

Tue 1/13

10:29 am-5:39 pm

1 stop10h 10m

$394

San DiegoMiami

SAN - MIA

SANMIA

San Diego

Sun 12/28

4:15 pm-5:00 am

1 stop9h 45m

Miami

Wed 1/14

8:00 am-3:40 pm

1 stop10h 40m

$394

Flights are sorted by cheapest round-trip flights first.

Deals found on 12/15

Showing 1-10 of 23 results
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Best time to book a flight from San Diego to Key Largo

Have a flexible travel schedule? Discover the best time to fly to Key Largo from San Diego with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from San Diego to Key Largo

How far ahead should I book a flight from San Diego to Key Largo?

Use this chart to determine the optimal time to book a round-trip flight from San Diego to Key Largo. Price data was last updated on December 12, 2025.

Booking 86 days in advance of your planned departure date is, on average, the best time to get cheap flights from San Diego to Key Largo. The general trend is that the closer you book to the departure date, the more expensive your flight will be.

What is the cheapest month to book a flight from San Diego to Key Largo?

Currently, May is the cheapest month in which you can book a flight from San Diego to Key Largo (average of $95). Flying from San Diego to Key Largo in December is currently the most expensive (average of $206). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

What is the cheapest time of day to fly from SAN to KE9?

Find hourly flight availability from San Diego to Key Largo. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated December 18, 2025.

It’s optimal to fly from San Diego to Key Largo in the afternoon. By choosing this option you can save up to 54% on the cost of your flight, compared to a flight in the morning.

What is the cheapest day to fly from San Diego to Key Largo?

Use this chart to determine the cheapest time to fly round-trip from San Diego to Key Largo. Price data was last updated on December 16, 2024.

Travelers seeking maximum savings on their San Diego to Key Largo flight should consider departing on Wednesday afternoons when fares are most often at their lowest. Monday mornings flights should be avoided if possible as fares are typically the most expensive at this time.

Reviews of airlines servicing Key Largo

Get insights into the airlines that provide service to Key Largo. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Key Largo. Reviews last updated December 18, 2025.
See what other customers who have flown with Alaska Airlines, Delta, and United Airlines from San Diego to Key Largo have to say. You can also see how each airline compares in terms of entertainment options, comfort, food, crew/service, and boarding process.
Alaska Airlines
8.0
Very good
11,478 reviews

Overall

8.0

Crew

8.5

Comfort

7.8

Entertainment

7.0

Food

7.1

Boarding

8.1

Reviews

1 / 20
2.0
Mediocre

Art,Dec 2025

SAN - OGG

It was a five hour flight and my seat did not recline. I have had three back surgeries and I’m solid bone for my L3 vertebrae all the way to my tailbone. My body has never hurt so much. There was no TV on this flight and only a small can of soda was free.
Alaska Airlines
8.0
Very good
11,478 reviews
Alaska Airlines
8.0
Very good
11,478 reviews

Overall

8.0

Crew

8.5

Comfort

7.8

Entertainment

7.0

Food

7.1

Boarding

8.1

Reviews

1 / 20
2.0
Mediocre

Art,Dec 2025

SAN - OGG

It was a five hour flight and my seat did not recline. I have had three back surgeries and I’m solid bone for my L3 vertebrae all the way to my tailbone. My body has never hurt so much. There was no TV on this flight and only a small can of soda was free.
Delta
7.9
Good
8,009 reviews
Alaska Airlines
8.0
Very good
11,478 reviews

Overall

8.0

Crew

8.5

Comfort

7.8

Entertainment

7.0

Food

7.1

Boarding

8.1

Reviews

1 / 20
2.0
Mediocre

Art,Dec 2025

SAN - OGG

It was a five hour flight and my seat did not recline. I have had three back surgeries and I’m solid bone for my L3 vertebrae all the way to my tailbone. My body has never hurt so much. There was no TV on this flight and only a small can of soda was free.
United Airlines
7.4
Good
9,093 reviews
Alaska Airlines
8.0
Very good
11,478 reviews

Overall

8.0

Crew

8.5

Comfort

7.8

Entertainment

7.0

Food

7.1

Boarding

8.1

Reviews

1 / 20
2.0
Mediocre

Art,Dec 2025

SAN - OGG

It was a five hour flight and my seat did not recline. I have had three back surgeries and I’m solid bone for my L3 vertebrae all the way to my tailbone. My body has never hurt so much. There was no TV on this flight and only a small can of soda was free.
American Airlines
7.2
Good
11,055 reviews
Alaska Airlines
8.0
Very good
11,478 reviews

Overall

8.0

Crew

8.5

Comfort

7.8

Entertainment

7.0

Food

7.1

Boarding

8.1

Reviews

1 / 20
2.0
Mediocre

Art,Dec 2025

SAN - OGG

It was a five hour flight and my seat did not recline. I have had three back surgeries and I’m solid bone for my L3 vertebrae all the way to my tailbone. My body has never hurt so much. There was no TV on this flight and only a small can of soda was free.
Frontier
5.8
Fair
3,081 reviews
Alaska Airlines
8.0
Very good
11,478 reviews

Overall

8.0

Crew

8.5

Comfort

7.8

Entertainment

7.0

Food

7.1

Boarding

8.1

Reviews

1 / 20
2.0
Mediocre

Art,Dec 2025

SAN - OGG

It was a five hour flight and my seat did not recline. I have had three back surgeries and I’m solid bone for my L3 vertebrae all the way to my tailbone. My body has never hurt so much. There was no TV on this flight and only a small can of soda was free.

Related info for your journey

Find useful and relevant information for your journey from San Diego to Key Largo. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • What airport do you fly from for flights from San Diego to Key Largo?

    San Diego (SAN), located 2.6 mi from the city center, is the airport you fly out of when you book flights from San Diego to Key Largo. 9 airlines have flights from San Diego to Key Largo on a regular basis. Booking flights from San Diego to Key Largo should not be difficult; the airport handles an average of 0 outbound flights to Key Largo per day.

  • How popular is this San Diego to Key Largo flight route?

    The San Diego to Key Largo flight path was viewed by 8 users in the past month. Keep an eye out for changes in search interest prior to high and low season.

  • How long is the flight from San Diego to Key Largo?

    Southwest, Delta, and United Airlines can get you from San Diego to Key Largo in just under 6h 50m. Your travel time can differ by up to 9h 50m. The distance between San Diego and Key Largo is about 2262 mi. Both multi-stop and nonstop flights can be found to your destination and back.

  • What are the cheapest airlines to fly from San Diego to Key Largo one-way?

    To fly one-way, consider booking your trip with Frontier, which is currently one of the cheapest options available, starting at $42. Spirit Airlines flights start at $59 while deals on Southwest start at $128 one-way.

  • What are the most reliable airlines from San Diego to Key Largo?

    Before booking your flight to Key Largo from San Diego, check out the most reliable airlines to get you to your destination on time: Alaska Airlines (90%), American Airlines (88%), GOL( 87%).

  • What are the cheapest flights from San Diego to Key Largo?

    The cheapest flight price from San Diego to Key Largo is $173. On average you can expect to pay $929. The most popular route, (San Diego - Miami), can usually be booked for $152.

  • Can I find deals for flights from San Diego to Key Largo that include hotel bookings?

    Yes. In addition to deals on San Diego to Key Largo flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from San Diego to Key Largo?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from San Diego to Key Largo.

  • Can I find deals for business class flights from San Diego to Key Largo?

    Yes. Cheapflights offers flight deals from San Diego to Key Largo by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from San Diego to Key Largo?

    Currently, May is the cheapest month in which you can book a flight from San Diego to Key Largo (average of $95). Flying from San Diego to Key Largo in December is currently the most expensive (average of $206). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

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Top 9 airlines flying from San Diego to Key Largo

Discover the top 9 airlines that operate flights from San Diego to Key Largo. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated December 18, 2025.
AirlineCheapestAverageFlexibilityOn-time
FrontierCheapest$86Average$233FlexibilityNo cancel feeOn-time62%
Spirit AirlinesCheapest$102Average$214FlexibilityNo cancel feeOn-time65%
American AirlinesCheapest$226Average$455FlexibilityNo cancel feeOn-time71%
Alaska AirlinesCheapest$227Average$512FlexibilityNo cancel feeOn-time75%
United AirlinesCheapest$237Average$400FlexibilityNo cancel feeOn-time69%
Hawaiian AirlinesCheapest$238Average$360FlexibilityNo cancel feeOn-time85%
JetBlueCheapest$241Average$418FlexibilityNo cancel feeOn-time62%
DeltaCheapest$254Average$385FlexibilityNo cancel feeOn-timeN/A
SouthwestCheapest$259Average$465FlexibilityNo cancel feeOn-time63%

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