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Key Largo

$128+ Cheap flights from San Diego (SAN) to Key Largo, FL

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 12/31. Fares are subject to change and may not be available on all flights or dates of travel.
SAN — MIA
Dec 2 — Dec 91
Tue 12/2
Tue 12/9
1 adult, Economy
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Cheapflights Tip: The best prices from San Diego to Key Largo are usually found in January or April, booked 21 days in advance, depart on a Wednesday or Friday and return on a Wednesday

Cheap flight deals from San Diego to Key Largo

Keep the following information in mind while searching for San Diego to Key Largo flight deals. Data was last updated November 2, 2025.

Most accurate provider

CheapOair
3 stars

Most trusted provider

CheapOair
3 stars

Round-trip from

$233
(CheapOair)

One-way from

$128
(Kiwi.com)

Popular in

December

Cheapest in

January

Average price

$459
Provider with most accurate pricing for San Diego-Miami flight deals.
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Provider most trusted by Cheapflights users for San Diego-Miami flights.
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From San Diego to Key Largo
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One-way flight from San Diego to Key Largo
Search Deals
Highest demand for flights based on searches. 2% potential increase in price ($11 potential increase over avg. RT price).
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Cheapest flight prices on average. 1% potential price decrease ($6 potential savings vs. average RT price).
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Average for round-trip flights in November 2025
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Find flight deals from San Diego to Key Largo

Cheapest flights from San Diego to Key Largo
Explore the most affordable flight options available from San Diego to Key Largo. Find the lowest fares from popular airlines and budget airlines, with prices last updated on November 2, 2025.

This CheapOair deal was found by Cheapflights users on 10/31. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure CheapOair is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 11/136:25 amSAN - MIA
1 stop12h 37mFrontier
Mon 11/176:00 amMIA - SAN
1 stop8h 17mFrontier
Deal found 10/31$233
This eDestinos deal was found by Cheapflights users on 11/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure eDestinos is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 11/186:58 amSAN - MIA
2 stops26h 31mFrontier
Mon 11/246:15 amMIA - SAN
1 stop28h 46mFrontier
Deal found 11/2$234
This Frontier deal was found by Cheapflights users on 10/31. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Frontier is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 12/64:47 pmSAN - MIA
1 stop9h 32mFrontier
Mon 12/83:36 pmMIA - SAN
1 stop11h 20mFrontier
Deal found 10/31$235
This CheapOair deal was found by Cheapflights users on 11/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure CheapOair is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 12/36:25 amSAN - MIA
1 stop19h 54mFrontier
Mon 12/227:05 amMIA - SAN
1 stop8h 33mFrontier
Deal found 11/1$236
This Kiwi.com deal was found by Cheapflights users on 11/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 12/96:34 amSAN - MIA
1 stop19h 45mMultiple Airlines
Tue 12/2310:13 amMIA - SAN
1 stop16h 34mMultiple Airlines
Deal found 11/1$237
This Kiwi.com deal was found by Cheapflights users on 10/31. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 12/36:25 amSAN - MIA
1 stop19h 54mFrontier
Wed 12/106:00 amMIA - SAN
2 stops14h 53mFrontier
Deal found 10/31$238
This Kiwi.com deal was found by Cheapflights users on 11/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 12/241:06 pmSAN - MIA
1 stop13h 29mMultiple Airlines
Wed 12/3110:13 amMIA - SAN
1 stop14h 52mMultiple Airlines
Deal found 11/2$239
This Kiwi.com deal was found by Cheapflights users on 10/31. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 12/56:45 amSAN - MIA
1 stop12h 42mFrontier
Mon 12/87:00 amMIA - SAN
2 stops19h 59mFrontier
Deal found 10/31$240
This eDestinos deal was found by Cheapflights users on 10/31. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure eDestinos is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 12/43:47 pmSAN - MIA
2 stops29h 59mFrontier
Thu 12/117:09 pmMIA - SAN
2 stops23h 43mFrontier
Deal found 10/31$241
This Kiwi.com deal was found by Cheapflights users on 11/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 11/246:25 amSAN - MIA
1 stop8h 46mMultiple Airlines
Tue 12/25:02 pmMIA - SAN
2 stops32h 44mMultiple Airlines
Deal found 11/1$242
This Frontier deal was found by Cheapflights users on 11/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Frontier is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 12/86:25 amSAN - MIA
1 stop13h 53mFrontier
Wed 12/247:05 amMIA - SAN
1 stop8h 06mFrontier
Deal found 11/1$243
This Kiwi.com deal was found by Cheapflights users on 11/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 12/96:34 amSAN - MIA
1 stop19h 45mFrontier
Mon 12/227:05 amMIA - SAN
1 stop8h 33mFrontier
Deal found 11/1$246

Cheapflights Fare Finder

 
Customize your flight search to find flights from San Diego to Key Largo that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated November 2, 2025.
Use the filters below to find and compare flights from San Diego to Key Largo that are best for you.

Fly from

San Diego

Fly to

Key Largo

Route

Depart

Return

Price

San DiegoMiami

SAN - MIA

SANMIA

San Diego

Mon 1/19

9:45 pm-11:20 am

1 stop10h 35m

Miami

Mon 1/26

6:55 am-6:45 pm

1 stop14h 50m

$282

San DiegoMiami

SAN - MIA

SANMIA

San Diego

Mon 1/26

9:45 pm-11:20 am

1 stop10h 35m

Miami

Sat 1/31

3:00 pm-9:40 pm

1 stop9h 40m

$294

San DiegoMiami

SAN - MIA

SANMIA

San Diego

Sat 1/17

9:00 am-10:35 pm

2 stops10h 35m

Miami

Tue 1/20

4:51 pm-9:56 pm

1 stop8h 05m

$347

San DiegoMiami

SAN - MIA

SANMIA

San Diego

Mon 1/26

10:30 am-10:00 pm

1 stop8h 30m

Miami

Sun 2/1

7:55 am-2:40 pm

1 stop9h 45m

$357

San DiegoMiami

SAN - MIA

SANMIA

San Diego

Tue 12/2

10:23 am-9:43 pm

1 stop8h 20m

Miami

Tue 12/9

11:55 am-8:48 pm

2 stops11h 53m

$362

San DiegoMiami

SAN - MIA

SANMIA

San Diego

Mon 11/24

6:30 am-6:09 pm

1 stop8h 39m

Miami

Thu 11/27

8:05 am-2:15 pm

1 stop9h 10m

$367

San DiegoMiami

SAN - MIA

SANMIA

San Diego

Sun 12/7

10:30 pm-2:45 pm

1 stop13h 15m

Miami

Tue 12/16

8:05 am-1:02 pm

1 stop7h 57m

$399

San DiegoMiami

SAN - MIA

SANMIA

San Diego

Wed 11/19

6:30 am-6:09 pm

1 stop8h 39m

Miami

Mon 11/24

8:05 am-2:15 pm

1 stop9h 10m

$413

San DiegoMiami

SAN - MIA

SANMIA

San Diego

Fri 11/7

11:10 am-11:25 pm

1 stop9h 15m

Miami

Sat 11/8

3:10 pm-8:15 pm

1 stop8h 05m

$419

San DiegoMiami

SAN - MIA

SANMIA

San Diego

Mon 12/8

6:30 am-9:59 pm

1 stop12h 29m

Miami

Tue 12/9

11:55 am-8:48 pm

2 stops11h 53m

$438

Flights are sorted by cheapest round-trip flights first.

Deals found on 10/30

Showing 1-10 of 22 results
1
2
3

Best time to book a flight from San Diego to Key Largo

Have a flexible travel schedule? Discover the best time to fly to Key Largo from San Diego with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from San Diego to Key Largo

How far ahead should I book a flight from San Diego to Key Largo?

Use this chart to determine the optimal time to book a round-trip flight from San Diego to Key Largo. Price data was last updated on October 31, 2025.

Booking 21 days in advance of your planned departure date is, on average, the best time to get cheap flights from San Diego to Key Largo. The general trend is that the closer you book to the departure date, the more expensive your flight will be.

What is the cheapest month to book a flight from San Diego to Key Largo?

Currently, November is the cheapest month in which you can book a flight from San Diego to Key Largo (average of $93). Flying from San Diego to Key Largo in October is currently the most expensive (average of $201). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

What is the cheapest time of day to fly from SAN to KE9?

Find hourly flight availability from San Diego to Key Largo. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated November 2, 2025.

It’s optimal to fly from San Diego to Key Largo in the afternoon. By choosing this option you can save up to 55% on the cost of your flight, compared to a flight in the morning.

What is the cheapest day to fly from San Diego to Key Largo?

Use this chart to determine the cheapest time to fly round-trip from San Diego to Key Largo. Price data was last updated on December 16, 2024.

Travelers seeking maximum savings on their San Diego to Key Largo flight should consider departing on Wednesday afternoons when fares are most often at their lowest. Monday mornings flights should be avoided if possible as fares are typically the most expensive at this time.

Weekly flight availability from San Diego to Key Largo

Explore weekly flight availability from San Diego to Key Largo. Discover flights operating on different days of the week, giving you the flexibility to choose a travel day that best fits your plans. Compare info to find the most convenient option for your journey. Data last updated November 2, 2025.

The most flights from SAN to KE9 are scheduled on a Monday (5 on average). You will have fewer flight options on Tuesday, which is when the least amount of flights are scheduled (4 on average).

Reviews of airlines servicing Key Largo

Get insights into the airlines that provide service to Key Largo. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Key Largo. Reviews last updated November 2, 2025.
See what other customers who have flown with Alaska Airlines, Delta, and American Airlines from San Diego to Key Largo have to say. You can also see how each airline compares in terms of entertainment options, comfort, food, crew/service, and boarding process.
Alaska Airlines
8.0
Very good
11,231 reviews

Crew

8.5

Entertainment

7.0

Food

7.1

Boarding

8.1

Overall

8.0

Comfort

7.8

Reviews

1 / 20
6.0
Good

Hannah,Aug 2025

SFO - SAN

Ticket said TSA pre check, but then the TSA agent said that Alaska Airlines has not actually entered the pre check information for the ticket, so I had to use regular security. During boarding, I have a disability and need to board early. The Alaska Airlines employee announced disability boarding, but then immediately announced 2 other groups to board, so I still had to fight the crowds. On the plane, the stewardess was brusk and rude. Seats were very uncomfortable, especially on lower back.
Alaska Airlines
8.0
Very good
11,231 reviews
Alaska Airlines
8.0
Very good
11,231 reviews

Crew

8.5

Entertainment

7.0

Food

7.1

Boarding

8.1

Overall

8.0

Comfort

7.8

Reviews

1 / 20
6.0
Good

Hannah,Aug 2025

SFO - SAN

Ticket said TSA pre check, but then the TSA agent said that Alaska Airlines has not actually entered the pre check information for the ticket, so I had to use regular security. During boarding, I have a disability and need to board early. The Alaska Airlines employee announced disability boarding, but then immediately announced 2 other groups to board, so I still had to fight the crowds. On the plane, the stewardess was brusk and rude. Seats were very uncomfortable, especially on lower back.
Delta
7.9
Good
7,998 reviews
Alaska Airlines
8.0
Very good
11,231 reviews

Crew

8.5

Entertainment

7.0

Food

7.1

Boarding

8.1

Overall

8.0

Comfort

7.8

Reviews

1 / 20
6.0
Good

Hannah,Aug 2025

SFO - SAN

Ticket said TSA pre check, but then the TSA agent said that Alaska Airlines has not actually entered the pre check information for the ticket, so I had to use regular security. During boarding, I have a disability and need to board early. The Alaska Airlines employee announced disability boarding, but then immediately announced 2 other groups to board, so I still had to fight the crowds. On the plane, the stewardess was brusk and rude. Seats were very uncomfortable, especially on lower back.
American Airlines
7.2
Good
11,034 reviews
Alaska Airlines
8.0
Very good
11,231 reviews

Crew

8.5

Entertainment

7.0

Food

7.1

Boarding

8.1

Overall

8.0

Comfort

7.8

Reviews

1 / 20
6.0
Good

Hannah,Aug 2025

SFO - SAN

Ticket said TSA pre check, but then the TSA agent said that Alaska Airlines has not actually entered the pre check information for the ticket, so I had to use regular security. During boarding, I have a disability and need to board early. The Alaska Airlines employee announced disability boarding, but then immediately announced 2 other groups to board, so I still had to fight the crowds. On the plane, the stewardess was brusk and rude. Seats were very uncomfortable, especially on lower back.
Spirit Airlines
6.3
Okay
8,122 reviews
Alaska Airlines
8.0
Very good
11,231 reviews

Crew

8.5

Entertainment

7.0

Food

7.1

Boarding

8.1

Overall

8.0

Comfort

7.8

Reviews

1 / 20
6.0
Good

Hannah,Aug 2025

SFO - SAN

Ticket said TSA pre check, but then the TSA agent said that Alaska Airlines has not actually entered the pre check information for the ticket, so I had to use regular security. During boarding, I have a disability and need to board early. The Alaska Airlines employee announced disability boarding, but then immediately announced 2 other groups to board, so I still had to fight the crowds. On the plane, the stewardess was brusk and rude. Seats were very uncomfortable, especially on lower back.
Frontier
5.8
Fair
3,119 reviews
Alaska Airlines
8.0
Very good
11,231 reviews

Crew

8.5

Entertainment

7.0

Food

7.1

Boarding

8.1

Overall

8.0

Comfort

7.8

Reviews

1 / 20
6.0
Good

Hannah,Aug 2025

SFO - SAN

Ticket said TSA pre check, but then the TSA agent said that Alaska Airlines has not actually entered the pre check information for the ticket, so I had to use regular security. During boarding, I have a disability and need to board early. The Alaska Airlines employee announced disability boarding, but then immediately announced 2 other groups to board, so I still had to fight the crowds. On the plane, the stewardess was brusk and rude. Seats were very uncomfortable, especially on lower back.

Related info for your journey

Find useful and relevant information for your journey from San Diego to Key Largo. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • What airport do you fly from for flights from San Diego to Key Largo?

    San Diego (SAN), located 2.6 mi from the city center, is the airport you fly out of when you book flights from San Diego to Key Largo. 9 airlines have flights from San Diego to Key Largo on a regular basis. Booking flights from San Diego to Key Largo should not be difficult; the airport handles an average of 4 outbound flights to Key Largo per day.

  • How popular is this San Diego to Key Largo flight route?

    The San Diego to Key Largo flight path was viewed by 8 users in the past month. Keep an eye out for changes in search interest prior to high and low season.

  • How long is the flight from San Diego to Key Largo?

    Southwest and United Airlines can get you from San Diego to Key Largo in just under 10h 35m. Your travel time can differ by up to . The distance between San Diego and Key Largo is about 2262 mi.

  • What are the most reliable airlines from San Diego to Key Largo?

    Before booking your flight to Key Largo from San Diego, check out the most reliable airlines to get you to your destination on time: American Airlines (89%), Alaska Airlines (89%), Qatar Airways( 72%).

  • What are the cheapest flights from San Diego to Key Largo?

    The cheapest flight price from San Diego to Key Largo is $138. On average you can expect to pay $1,138. The most popular route, (San Diego - Miami), can usually be booked for $141.

  • Can I find deals for flights from San Diego to Key Largo that include hotel bookings?

    Yes. In addition to deals on San Diego to Key Largo flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from San Diego to Key Largo?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from San Diego to Key Largo.

  • Can I find deals for business class flights from San Diego to Key Largo?

    Yes. Cheapflights offers flight deals from San Diego to Key Largo by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from San Diego to Key Largo?

    Currently, November is the cheapest month in which you can book a flight from San Diego to Key Largo (average of $93). Flying from San Diego to Key Largo in October is currently the most expensive (average of $201). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

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Top 9 airlines flying from San Diego to Key Largo

Discover the top 9 airlines that operate flights from San Diego to Key Largo. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated November 2, 2025.
AirlineCheapestAverageFlexibilityOn-time
FrontierCheapest$89Average$215FlexibilityNo cancel feeOn-time62%
Spirit AirlinesCheapest$121Average$214FlexibilityNo cancel feeOn-time65%
American AirlinesCheapest$216Average$452FlexibilityNo cancel feeOn-time71%
JetBlueCheapest$226Average$527FlexibilityNo cancel feeOn-time62%
Alaska AirlinesCheapest$227Average$512FlexibilityNo cancel feeOn-time75%
United AirlinesCheapest$237Average$411FlexibilityNo cancel feeOn-time69%
Hawaiian AirlinesCheapest$238Average$360FlexibilityNo cancel feeOn-time85%
DeltaCheapest$255Average$377FlexibilityNo cancel feeOn-timeN/A
SouthwestCheapest$262Average$471FlexibilityNo cancel feeOn-time63%

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