$136+ Cheap flights from San Diego (SAN) to Key Largo, FL
This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 4/1. Fares are subject to change and may not be available on all flights or dates of travel.
SAN — MIA
Mar 5 — Mar 121
1 adult, Economy
We work with more than 300 partners to bring you better travel deals
Find cheap flights from San Diego to Key Largo with Cheapflights
1. Tell us where you want to go
Enter your travel information like dates, passengers, trip type (one-way or round trip), and preferred cabin class then click “Find deals”2. Select your favorite providers
We find the providers serving your travel needs. Choose up to four travel providers to compare side-by-side for flights, hotels, or car rentals.3. Compare prices and book
Review each provider’s pricing and select the best option for you! Book through your favorite provider’s website for a seamless experience.Cheapflights Tip: The best prices from San Diego to Key Largo are usually found in April or October, booked 68 days in advance, depart on a Saturday or Friday and return on a Wednesday
Cheap flight deals from San Diego to Key Largo
Cheapest
Best
Last-minute
One-way
Cheapest flights from San Diego to Key LargoExplore the most affordable flight options available from San Diego to Key Largo. Find the lowest fares from popular airlines and budget airlines, with prices last updated on February 3, 2026.
Explore the most affordable flight options available from San Diego to Key Largo. Find the lowest fares from popular airlines and budget airlines, with prices last updated on February 3, 2026.
This Kiwi.com deal was found by Cheapflights users on 2/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 3/236:25 am
SAN
- MIA
1 stop13h 27m
Multiple Airlines
Fri 4/38:35 pm
MIA
- SAN
1 stop28h 00m
Multiple Airlines
Deal found 2/3![Multiple Airlines logo]()
$259
This Kiwi.com deal was found by Cheapflights users on 2/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 2/208:35 am
SAN
- MIA
1 stop17h 39m
Frontier
Wed 2/255:45 am
MIA
- SAN
1 stop18h 56m
Frontier
Deal found 2/1![Frontier logo]()
$260
This Kiwi.com deal was found by Cheapflights users on 2/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 2/166:25 am
SAN
- MIA
1 stop19h 49m
Multiple Airlines
Thu 2/194:01 pm
MIA
- SAN
1 stop19h 49m
Multiple Airlines
Deal found 2/2![Multiple Airlines logo]()
$261
This Kiwi.com deal was found by Cheapflights users on 2/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 2/196:25 am
SAN
- MIA
1 stop19h 49m
Frontier
Fri 2/2710:17 pm
MIA
- SAN
1 stop15h 09m
Frontier
Deal found 2/1![Frontier logo]()
$263
This Kiwi.com deal was found by Cheapflights users on 2/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 3/256:25 am
SAN
- MIA
1 stop20h 13m
Frontier
Mon 3/305:15 am
MIA
- SAN
1 stop21h 12m
Frontier
Deal found 2/2![Frontier logo]()
$264
This Kiwi.com deal was found by Cheapflights users on 2/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 3/252:50 pm
SAN
- MIA
2 stops11h 48m
Multiple Airlines
Sat 3/288:35 pm
MIA
- SAN
1 stop30h 41m
Multiple Airlines
Deal found 2/3![Multiple Airlines logo]()
$266
This CheapOair deal was found by Cheapflights users on 2/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure CheapOair is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 2/276:25 am
SAN
- MIA
1 stop19h 49m
Frontier
Wed 3/46:25 am
MIA
- SAN
1 stop18h 16m
Frontier
Deal found 2/3![Frontier logo]()
$267
This Expedia deal was found by Cheapflights users on 2/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Expedia is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 3/66:55 am
SAN
- MIA
1 stop13h 13m
Frontier
Mon 3/95:50 am
MIA
- SAN
1 stop17h 43m
Frontier
Deal found 2/2![Frontier logo]()
$268
This Frontier deal was found by Cheapflights users on 2/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Frontier is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 4/2412:36 pm
SAN
- MIA
1 stop13h 29m
Frontier
Fri 5/15:45 pm
MIA
- SAN
1 stop9h 26m
Frontier
Deal found 2/1![Frontier logo]()
$269
This Frontier deal was found by Cheapflights users on 2/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Frontier is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 4/249:07 pm
SAN
- MIA
1 stop7h 25m
Frontier
Sun 4/265:45 pm
MIA
- SAN
1 stop9h 26m
Frontier
Deal found 2/1![Frontier logo]()
$270
This eDestinos deal was found by Cheapflights users on 2/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure eDestinos is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 2/208:35 am
SAN
- MIA
1 stop17h 39m
Frontier
Sun 2/226:45 am
MIA
- SAN
1 stop31h 00m
Frontier
Deal found 2/1![Frontier logo]()
$272
This Kiwi.com deal was found by Cheapflights users on 2/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 2/276:25 am
SAN
- MIA
1 stop19h 49m
Frontier
Sun 3/16:45 am
MIA
- SAN
1 stop20h 23m
Frontier
Deal found 2/3![Frontier logo]()
$273
Best flights from San Diego to Key LargoDiscover carefully curated flight deals from San Diego to Key Largo that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated February 3, 2026.
Discover carefully curated flight deals from San Diego to Key Largo that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated February 3, 2026.
This Southwest deal was found by Cheapflights users on 2/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 4/41:15 pm
SAN
- MIA
2 stops8h 25m
Southwest
Sat 4/114:45 pm
MIA
- SAN
2 stops9h 40m
Southwest
Deal found 2/1![Southwest logo]()
$351
This Delta deal was found by Cheapflights users on 2/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 4/42:18 pm
SAN
- MIA
1 stop7h 34m
Delta
Tue 4/78:05 am
MIA
- SAN
1 stop9h 49m
Delta
Deal found 2/2![Delta logo]()
$359
This United Airlines deal was found by Cheapflights users on 1/31. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 2/235:00 pm
SAN
- MIA
1 stop17h 13m
United Airlines
Thu 2/265:35 pm
MIA
- SAN
1 stop19h 12m
United Airlines
Deal found 1/31![United Airlines logo]()
$419
This Southwest deal was found by Cheapflights users on 2/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 3/249:35 am
SAN
- MIA
2 stops9h 40m
Southwest
Wed 3/2511:40 am
MIA
- SAN
2 stops12h 35m
Southwest
Deal found 2/3![Southwest logo]()
$369
This Southwest deal was found by Cheapflights users on 1/31. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 4/37:30 pm
SAN
- MIA
1 stop12h 40m
Southwest
Sat 4/114:45 pm
MIA
- SAN
2 stops9h 40m
Southwest
Deal found 1/31![Southwest logo]()
$372
This Delta deal was found by Cheapflights users on 1/31. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 3/1410:10 pm
SAN
- MIA
1 stop9h 05m
Delta
Sat 3/218:05 am
MIA
- SAN
1 stop9h 49m
Delta
Deal found 1/31![Delta logo]()
$419
This Southwest deal was found by Cheapflights users on 2/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 4/41:15 pm
SAN
- MIA
2 stops8h 25m
Southwest
Fri 4/105:30 am
MIA
- SAN
1 stop7h 05m
Southwest
Deal found 2/1![Southwest logo]()
$388
This Southwest deal was found by Cheapflights users on 2/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 3/810:40 pm
SAN
- MIA
2 stops12h 10m
Southwest
Wed 3/1112:55 pm
MIA
- SAN
2 stops11h 15m
Southwest
Deal found 2/3![Southwest logo]()
$402
This Southwest deal was found by Cheapflights users on 2/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 3/216:45 am
SAN
- MIA
1 stop13h 15m
Southwest
Tue 3/246:30 am
MIA
- SAN
1 stop9h 05m
Southwest
Deal found 2/3![Southwest logo]()
$406
This Southwest deal was found by Cheapflights users on 2/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 2/148:15 am
SAN
- MIA
2 stops13h 05m
Southwest
Wed 2/1812:55 pm
MIA
- SAN
2 stops10h 55m
Southwest
Deal found 2/1![Southwest logo]()
$413
This Southwest deal was found by Cheapflights users on 2/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 5/28:20 pm
SAN
- MIA
2 stops12h 20m
Southwest
Mon 5/45:30 am
MIA
- SAN
2 stops10h 10m
Southwest
Deal found 2/2![Southwest logo]()
$419
This Southwest deal was found by Cheapflights users on 1/31. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 3/142:55 pm
SAN
- MIA
1 stop6h 45m
Southwest
Sat 3/215:15 am
MIA
- SAN
2 stops10h 15m
Southwest
Deal found 1/31![Southwest logo]()
$427
Last-minute flights from San Diego to Key LargoDiscover last-minute flight deals from San Diego to Key Largo. Data last updated February 3, 2026 and is based on user searches.
Discover last-minute flight deals from San Diego to Key Largo. Data last updated February 3, 2026 and is based on user searches.
This Kiwi.com deal was found by Cheapflights users on 2/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 2/166:25 am
SAN
- MIA
1 stop19h 49m
Multiple Airlines
Thu 2/194:01 pm
MIA
- SAN
1 stop19h 49m
Multiple Airlines
Deal found 2/2![Multiple Airlines logo]()
$261
This Kiwi.com deal was found by Cheapflights users on 2/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 2/196:25 am
SAN
- MIA
1 stop19h 49m
Frontier
Fri 2/2710:17 pm
MIA
- SAN
1 stop15h 09m
Frontier
Deal found 2/1![Frontier logo]()
$263
This Kiwi.com deal was found by Cheapflights users on 2/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 2/208:35 am
SAN
- MIA
1 stop17h 39m
Frontier
Wed 2/255:45 am
MIA
- SAN
1 stop18h 56m
Frontier
Deal found 2/1![Frontier logo]()
$260
This eDestinos deal was found by Cheapflights users on 2/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure eDestinos is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 2/208:35 am
SAN
- MIA
1 stop17h 39m
Frontier
Sun 2/226:45 am
MIA
- SAN
1 stop31h 00m
Frontier
Deal found 2/1![Frontier logo]()
$272
This Kiwi.com deal was found by Cheapflights users on 2/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 2/2611:59 am
SAN
- MIA
1 stop14h 15m
Frontier
Mon 3/27:17 pm
MIA
- SAN
2 stops29h 24m
Frontier
Deal found 2/3![Frontier logo]()
$274
This CheapOair deal was found by Cheapflights users on 2/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure CheapOair is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 2/276:25 am
SAN
- MIA
1 stop19h 49m
Frontier
Wed 3/46:25 am
MIA
- SAN
1 stop18h 16m
Frontier
Deal found 2/3![Frontier logo]()
$267
This Kiwi.com deal was found by Cheapflights users on 2/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 2/276:25 am
SAN
- MIA
1 stop19h 49m
Frontier
Sun 3/16:45 am
MIA
- SAN
1 stop20h 23m
Frontier
Deal found 2/3![Frontier logo]()
$273
This Expedia deal was found by Cheapflights users on 2/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Expedia is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 3/66:55 am
SAN
- MIA
1 stop13h 13m
Frontier
Mon 3/95:50 am
MIA
- SAN
1 stop17h 43m
Frontier
Deal found 2/2![Frontier logo]()
$268
This Kiwi.com deal was found by Cheapflights users on 2/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 3/236:25 am
SAN
- MIA
1 stop13h 27m
Multiple Airlines
Thu 4/28:35 pm
MIA
- SAN
1 stop30h 09m
Multiple Airlines
Deal found 2/3![Multiple Airlines logo]()
$259
This Kiwi.com deal was found by Cheapflights users on 2/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 3/256:25 am
SAN
- MIA
1 stop20h 13m
Frontier
Mon 3/305:15 am
MIA
- SAN
1 stop21h 12m
Frontier
Deal found 2/2![Frontier logo]()
$264
This Kiwi.com deal was found by Cheapflights users on 2/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 3/252:50 pm
SAN
- MIA
2 stops11h 48m
Multiple Airlines
Sat 3/288:35 pm
MIA
- SAN
1 stop30h 41m
Multiple Airlines
Deal found 2/3![Multiple Airlines logo]()
$266
This Kiwi.com deal was found by Cheapflights users on 2/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 3/266:55 am
SAN
- MIA
1 stop13h 59m
Multiple Airlines
Sat 4/48:35 pm
MIA
- SAN
2 stops30h 27m
Multiple Airlines
Deal found 2/3![Multiple Airlines logo]()
$270
One-way flights from San Diego to Key LargoSearch for one-way flight options from San Diego to Key Largo. Find affordable one-way fares based on user searches. Data last updated February 3, 2026.
Search for one-way flight options from San Diego to Key Largo. Find affordable one-way fares based on user searches. Data last updated February 3, 2026.
This Kiwi.com deal was found by Cheapflights users on 2/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 4/16:25 am
SAN
- MIA
1 stop20h 24m
Frontier
Deal found 2/1![Frontier logo]()
$136
This Trip.com deal was found by Cheapflights users on 2/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Trip.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 3/116:25 am
SAN
- MIA
1 stop20h 13m
Frontier
Deal found 2/1![Frontier logo]()
$137
This Kiwi.com deal was found by Cheapflights users on 2/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 3/94:29 pm
SAN
- MIA
3 stops20h 08m
Multiple Airlines
Deal found 2/1![Multiple Airlines logo]()
$138
This Kiwi.com deal was found by Cheapflights users on 2/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 2/218:00 am
SAN
- MIA
2 stops26h 03m
Frontier
Deal found 2/2![Frontier logo]()
$143
This Kiwi.com deal was found by Cheapflights users on 2/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 2/1411:21 am
SAN
- MIA
2 stops21h 55m
Multiple Airlines
Deal found 2/1![Multiple Airlines logo]()
$144
This Frontier deal was found by Cheapflights users on 2/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Frontier is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 2/279:45 am
SAN
- MIA
1 stop8h 24m
Frontier
Deal found 2/1![Frontier logo]()
$145
This Kiwi.com deal was found by Cheapflights users on 2/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 3/511:59 am
SAN
- MIA
1 stop14h 15m
Frontier
Deal found 2/2![Frontier logo]()
$146
This Kiwi.com deal was found by Cheapflights users on 2/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 2/228:10 pm
SAN
- MIA
3 stops36h 30m
Multiple Airlines
Deal found 2/3![Multiple Airlines logo]()
$147
This Kiwi.com deal was found by Cheapflights users on 2/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 3/16:25 am
SAN
- MIA
1 stop19h 49m
Frontier
Deal found 2/1![Frontier logo]()
$148
This Super.com deal was found by Cheapflights users on 2/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Super.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 2/229:09 am
SAN
- MIA
1 stop17h 05m
Frontier
Deal found 2/1![Frontier logo]()
$149
This Kiwi.com deal was found by Cheapflights users on 2/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 3/89:07 pm
SAN
- MIA
3 stops39h 30m
Multiple Airlines
Deal found 2/3![Multiple Airlines logo]()
$150
This Kiwi.com deal was found by Cheapflights users on 2/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 3/69:58 pm
SAN
- MIA
3 stops46h 11m
Multiple Airlines
Deal found 2/2![Multiple Airlines logo]()
$151
Find flight deals from San Diego to Key Largo
Keep the following information in mind while searching for San Diego to Key Largo flight deals. Data was last updated February 3, 2026.
Most accurate provider | FlightHub 3 stars |
|---|---|
Most trusted provider | FlightHub 3 stars |
Round-trip from | $259 (Kiwi.com) |
One-way from | $136 (Kiwi.com) |
Popular in | December |
Cheapest in | April |
Average price | $473 |
Cheapflights Fare Finder
Customize your flight search to find flights from San Diego to Key Largo that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated February 3, 2026.
Use the filters below to find and compare flights from San Diego to Key Largo that are best for you.
Fly from
San Diego
Fly to
Key Largo
Route
Depart
Return
Price
San DiegoMiami
SAN - MIA
SANMIA
San Diego
Sat 4/4
1:15 pm-12:40 am
2 stops8h 25m
Miami
Sat 4/11
4:45 pm-11:25 pm
2 stops9h 40m
$351
San DiegoMiami
SAN - MIA
SANMIA
San Diego
Sat 4/4
2:18 pm-12:52 am
1 stop7h 34m
Miami
Tue 4/7
8:05 am-2:54 pm
1 stop9h 49m
$359
San DiegoMiami
SAN - MIA
SANMIA
San Diego
Tue 3/24
9:35 am-10:15 pm
2 stops9h 40m
Miami
Wed 3/25
11:40 am-9:15 pm
2 stops12h 35m
$369
San DiegoMiami
SAN - MIA
SANMIA
San Diego
Fri 4/3
7:30 pm-11:10 am
1 stop12h 40m
Miami
Sat 4/11
4:45 pm-11:25 pm
2 stops9h 40m
$372
San DiegoMiami
SAN - MIA
SANMIA
San Diego
Sat 4/4
1:15 pm-12:40 am
2 stops8h 25m
Miami
Fri 4/10
5:30 am-9:35 am
1 stop7h 05m
$388
San DiegoMiami
SAN - MIA
SANMIA
San Diego
Sun 3/8
10:40 pm-1:50 pm
2 stops12h 10m
Miami
Wed 3/11
12:55 pm-9:10 pm
2 stops11h 15m
$402
San DiegoMiami
SAN - MIA
SANMIA
San Diego
Sat 3/21
6:45 am-11:00 pm
1 stop13h 15m
Miami
Tue 3/24
6:30 am-12:35 pm
1 stop9h 05m
$406
San DiegoMiami
SAN - MIA
SANMIA
San Diego
Sat 2/14
8:15 am-12:20 am
2 stops13h 05m
Miami
Wed 2/18
12:55 pm-8:50 pm
2 stops10h 55m
$413
San DiegoMiami
SAN - MIA
SANMIA
San Diego
Mon 2/23
5:00 pm-1:13 pm
1 stop17h 13m
Miami
Thu 2/26
5:35 pm-9:47 am
1 stop19h 12m
$419
San DiegoMiami
SAN - MIA
SANMIA
San Diego
Sat 3/14
10:10 pm-10:15 am
1 stop9h 05m
Miami
Sat 3/21
8:05 am-2:54 pm
1 stop9h 49m
$419
Showing 1-10 of 23 results
Best time to book a flight from San Diego to Key Largo
Have a flexible travel schedule? Discover the best time to fly to Key Largo from San Diego with our price prediction graph.
SAN-MIA
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.
Cheapflights Insights
Everything you need to know about your flight from San Diego to Key Largo
SAN-KE9
SAN-MIA
How far ahead should I book a flight from San Diego to Key Largo?
Use this chart to determine the optimal time to book a round-trip flight from San Diego to Key Largo. Price data was last updated on January 30, 2026.
Booking 68 days in advance of your planned departure date is, on average, the best time to get cheap flights from San Diego to Key Largo. The general trend is that the closer you book to the departure date, the more expensive your flight will be.
What is the cheapest month to book a flight from San Diego to Key Largo?
Currently, May is the cheapest month in which you can book a flight from San Diego to Key Largo (average of $95). Flying from San Diego to Key Largo in December is currently the most expensive (average of $207). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.
What is the cheapest time of day to fly from SAN to KE9?
Find hourly flight availability from San Diego to Key Largo. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated February 3, 2026.
It’s optimal to fly from San Diego to Key Largo in the afternoon. By choosing this option you can save up to 25% on the cost of your flight, compared to a flight in the morning.
Weekly flight availability from San Diego to Key Largo
Explore weekly flight availability from San Diego to Key Largo. Discover flights operating on different days of the week, giving you the flexibility to choose a travel day that best fits your plans. Compare info to find the most convenient option for your journey. Data last updated February 3, 2026.
The most flights from SAN to KE9 are scheduled on a Tuesday (7 on average). You will have fewer flight options on Wednesday, which is when the least amount of flights are scheduled (4 on average).
Reviews of airlines servicing Key Largo
Get insights into the airlines that provide service to Key Largo. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Key Largo. Reviews last updated February 3, 2026.
See what other customers who have flown with Alaska Airlines, Delta, and United Airlines from San Diego to Key Largo have to say. You can also see how each airline compares in terms of entertainment options, comfort, food, crew/service, and boarding process.
Food
7.1
Boarding
8.1
Crew
8.5
Overall
8.0
Entertainment
7.0
Comfort
7.8
Reviews
1 / 20
10.0
ExcellentAnonymous,Jan 2026
STS - LAX
Food
7.1
Boarding
8.1
Crew
8.5
Overall
8.0
Entertainment
7.0
Comfort
7.8
Reviews
1 / 20
10.0
ExcellentAnonymous,Jan 2026
STS - LAX
Food
7.1
Boarding
8.1
Crew
8.5
Overall
8.0
Entertainment
7.0
Comfort
7.8
Reviews
1 / 20
10.0
ExcellentAnonymous,Jan 2026
STS - LAX
Food
7.1
Boarding
8.1
Crew
8.5
Overall
8.0
Entertainment
7.0
Comfort
7.8
Reviews
1 / 20
10.0
ExcellentAnonymous,Jan 2026
STS - LAX
Food
7.1
Boarding
8.1
Crew
8.5
Overall
8.0
Entertainment
7.0
Comfort
7.8
Reviews
1 / 20
10.0
ExcellentAnonymous,Jan 2026
STS - LAX
Food
7.1
Boarding
8.1
Crew
8.5
Overall
8.0
Entertainment
7.0
Comfort
7.8
Reviews
1 / 20
10.0
ExcellentAnonymous,Jan 2026
STS - LAX
Related info for your journey
Find useful and relevant information for your journey from San Diego to Key Largo. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.
Browse thousands of different options on Cheapflights for your next trip
Toggle through the tabs below to find thousands of options on Cheapflights for your next trip.
Alternative routes
Complete your trip
Flights by cabin class
Other flight options
Other flights from San Diego
Popular flights
Top destinations
Alternative routes for San Diego to Key Largo
See prices for flight routes from nearby airports that may be better suited for you.
Complete your trip
Complete your trip to Key Largo by adding a car rental and/or hotel reservation to your travel itinerary.
Search flights from San Diego to Key Largo by cabin class
Find flights from San Diego to Key Largo, based on your preferred cabin class, be it economy, premium economy, business, or first class.
San Diego and Key Largo flights
Browse other San Diego and Key Largo flight options. Last updated on February 3, 2026.
Other flights from San Diego
Browse through other flights departing from San Diego. Flights are based on user searches made on Cheapflights and were last updated on February 3, 2026.
Popular flight searches
Check out other popular destinations found by fellow travelers in 2026
San Diego to Key Largo flights
Consider these flights traveling from San Diego to Key Largo.
Top 8 airlines flying from San Diego to Key Largo
Discover the top 8 airlines that operate flights from San Diego to Key Largo. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated February 3, 2026.
| Airline | Cheapest | Average | Flexibility | On-time |
|---|---|---|---|---|
| Cheapest$89 | Average$235 | FlexibilityNo cancel fee | On-time62% | |
| Cheapest$90 | Average$215 | FlexibilityNo cancel fee | On-time65% | |
| Cheapest$199 | Average$357 | FlexibilityNo cancel fee | On-time85% | |
| Cheapest$216 | Average$442 | FlexibilityNo cancel fee | On-time71% | |
| Cheapest$217 | Average$508 | FlexibilityNo cancel fee | On-time75% | |
| Cheapest$236 | Average$384 | FlexibilityNo cancel fee | On-time69% | |
| Cheapest$246 | Average$352 | FlexibilityNo cancel fee | On-timeN/A | |
| Cheapest$251 | Average$456 | FlexibilityNo cancel fee | On-time63% |