$208+ Cheap flights from San Diego (SAN) to Key Largo, FL
This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 5/1. Fares are subject to change and may not be available on all flights or dates of travel.
SAN — MIA
Apr 28 — May 51
Round-trip
1 adult, Economy
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Find cheap flights from San Diego to Key Largo with Cheapflights
1. Tell us where you want to go
Enter your travel information like dates, passengers, trip type (one-way or round trip), and preferred cabin class then click “Find deals”2. Select your favorite providers
We find the providers serving your travel needs. Choose up to four travel providers to compare side-by-side for flights, hotels, or car rentals.3. Compare prices and book
Review each provider’s pricing and select the best option for you! Book through your favorite provider’s website for a seamless experience.Cheapflights Tip: The best prices from San Diego to Key Largo are usually found in January or October, booked 81 days in advance, depart on a Saturday or Friday and return on a Saturday
Cheap flight deals from San Diego to Key Largo
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Best
Last-minute
One-way
Cheapest flights from San Diego to Key LargoExplore the most affordable flight options available from San Diego to Key Largo. Find the lowest fares from popular airlines and budget airlines, with prices last updated on March 29, 2026.
Explore the most affordable flight options available from San Diego to Key Largo. Find the lowest fares from popular airlines and budget airlines, with prices last updated on March 29, 2026.
This Expedia deal was found by Cheapflights users on 3/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Expedia is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 3/309:00 am
SAN
- MIA
1 stop17h 38m
Frontier
Sun 4/55:50 am
MIA
- SAN
1 stop21h 12m
Frontier
Deal found 3/28![Frontier logo]()
$370
This CheapOair deal was found by Cheapflights users on 3/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure CheapOair is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 3/279:18 pm
SAN
- MIA
1 stop29h 20m
Frontier
Mon 3/307:59 pm
MIA
- SAN
1 stop31h 09m
Frontier
Deal found 3/26![Frontier logo]()
$371
This Super.com deal was found by Cheapflights users on 3/24. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Super.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 4/98:47 am
SAN
- MIA
1 stop18h 02m
Frontier
Sun 4/1212:59 pm
MIA
- SAN
1 stop13h 27m
Frontier
Deal found 3/24![Frontier logo]()
$372
This Southwest deal was found by Cheapflights users on 3/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 4/279:35 am
SAN
- MIA
2 stops9h 25m
Southwest
Wed 5/63:00 pm
MIA
- SAN
2 stops9h 30m
Southwest
Deal found 3/26![Southwest logo]()
$373
This Expedia deal was found by Cheapflights users on 3/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Expedia is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 3/296:55 am
SAN
- MIA
1 stop13h 59m
Frontier
Tue 3/315:50 am
MIA
- SAN
1 stop21h 18m
Frontier
Deal found 3/25![Frontier logo]()
$375
This eDestinos deal was found by Cheapflights users on 3/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure eDestinos is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 6/179:53 pm
SAN
- MIA
2 stops23h 23m
Frontier
Mon 6/225:26 pm
MIA
- SAN
2 stops28h 20m
Frontier
Deal found 3/26![Frontier logo]()
$376
This Kiwi.com deal was found by Cheapflights users on 3/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 5/236:25 am
SAN
- MIA
1 stop11h 52m
Multiple Airlines
Sun 5/315:05 am
MIA
- SAN
1 stop9h 19m
Multiple Airlines
Deal found 3/25![Multiple Airlines logo]()
$377
This Southwest deal was found by Cheapflights users on 3/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 4/3010:40 pm
SAN
- MIA
2 stops15h 50m
Southwest
Tue 5/53:00 pm
MIA
- SAN
2 stops9h 30m
Southwest
Deal found 3/26![Southwest logo]()
$378
This American Airlines deal was found by Cheapflights users on 3/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 5/210:05 pm
SAN
- MIA
Nonstop4h 55m
American Airlines
Sat 5/98:40 am
MIA
- SAN
Nonstop5h 36m
American Airlines
Deal found 3/27![American Airlines logo]()
$379
This CheapOair deal was found by Cheapflights users on 3/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure CheapOair is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 4/28:47 am
SAN
- MIA
1 stop18h 02m
Frontier
Sun 4/512:59 pm
MIA
- SAN
1 stop13h 27m
Frontier
Deal found 3/25![Frontier logo]()
$380
This CheapOair deal was found by Cheapflights users on 3/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure CheapOair is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 3/296:55 am
SAN
- MIA
1 stop13h 59m
Frontier
Sun 4/55:50 am
MIA
- SAN
1 stop17h 36m
Frontier
Deal found 3/26![Frontier logo]()
$381
This Kiwi.com deal was found by Cheapflights users on 3/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 5/296:25 am
SAN
- MIA
2 stops14h 04m
Multiple Airlines
Thu 6/45:05 am
MIA
- SAN
1 stop9h 19m
Multiple Airlines
Deal found 3/25![Multiple Airlines logo]()
$382
Best flights from San Diego to Key LargoDiscover carefully curated flight deals from San Diego to Key Largo that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated March 29, 2026.
Discover carefully curated flight deals from San Diego to Key Largo that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated March 29, 2026.
This Southwest deal was found by Cheapflights users on 3/24. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 4/276:55 am
SAN
- MIA
2 stops8h 30m
Southwest
Wed 5/612:10 pm
MIA
- SAN
2 stops10h 45m
Southwest
Deal found 3/24![Southwest logo]()
$373
This Delta deal was found by Cheapflights users on 3/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 4/226:25 am
SAN
- MIA
1 stop8h 41m
Delta
Tue 4/286:42 am
MIA
- SAN
1 stop8h 26m
Delta
Deal found 3/26![Delta logo]()
$440
This Southwest deal was found by Cheapflights users on 3/24. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 4/196:20 am
SAN
- MIA
2 stops9h 55m
Southwest
Tue 4/283:00 pm
MIA
- SAN
2 stops9h 30m
Southwest
Deal found 3/24![Southwest logo]()
$409
This Delta deal was found by Cheapflights users on 3/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 7/3012:59 pm
SAN
- MIA
1 stop7h 40m
Delta
Sun 8/28:20 am
MIA
- SAN
1 stop9h 49m
Delta
Deal found 3/28![Delta logo]()
$465
This Southwest deal was found by Cheapflights users on 3/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 4/186:25 am
SAN
- MIA
1 stop6h 40m
Southwest
Sat 4/185:40 pm
MIA
- SAN
1 stop7h 05m
Southwest
Deal found 3/28![Southwest logo]()
$437
This Southwest deal was found by Cheapflights users on 3/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 8/97:50 pm
SAN
- MIA
2 stops12h 35m
Southwest
Sat 8/152:15 pm
MIA
- SAN
1 stop7h 10m
Southwest
Deal found 3/28![Southwest logo]()
$437
This Southwest deal was found by Cheapflights users on 3/24. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 8/110:40 pm
SAN
- MIA
1 stop12h 50m
Southwest
Fri 8/75:45 am
MIA
- SAN
2 stops8h 30m
Southwest
Deal found 3/24![Southwest logo]()
$443
This Southwest deal was found by Cheapflights users on 3/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 8/110:40 pm
SAN
- MIA
1 stop12h 50m
Southwest
Sat 8/87:00 am
MIA
- SAN
2 stops10h 35m
Southwest
Deal found 3/28![Southwest logo]()
$443
This Southwest deal was found by Cheapflights users on 3/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 6/66:25 am
SAN
- MIA
2 stops13h 35m
Southwest
Fri 6/123:20 pm
MIA
- SAN
2 stops8h 45m
Southwest
Deal found 3/27![Southwest logo]()
$448
This Southwest deal was found by Cheapflights users on 3/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 5/287:55 am
SAN
- MIA
2 stops12h 05m
Southwest
Fri 5/295:30 am
MIA
- SAN
2 stops9h 40m
Southwest
Deal found 3/26![Southwest logo]()
$461
This Southwest deal was found by Cheapflights users on 3/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 9/2510:40 pm
SAN
- MIA
1 stop9h 15m
Southwest
Mon 9/285:45 am
MIA
- SAN
2 stops9h 50m
Southwest
Deal found 3/26![Southwest logo]()
$470
This Southwest deal was found by Cheapflights users on 3/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 7/3011:55 am
SAN
- MIA
2 stops9h 30m
Southwest
Sun 8/25:00 am
MIA
- SAN
1 stop7h 05m
Southwest
Deal found 3/28![Southwest logo]()
$470
Last-minute flights from San Diego to Key LargoDiscover last-minute flight deals from San Diego to Key Largo. Data last updated March 29, 2026 and is based on user searches.
Discover last-minute flight deals from San Diego to Key Largo. Data last updated March 29, 2026 and is based on user searches.
This CheapOair deal was found by Cheapflights users on 3/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure CheapOair is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 3/279:18 pm
SAN
- MIA
1 stop29h 20m
Frontier
Mon 3/307:59 pm
MIA
- SAN
1 stop31h 09m
Frontier
Deal found 3/26![Frontier logo]()
$371
This Super.com deal was found by Cheapflights users on 3/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Super.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 3/279:18 pm
SAN
- MIA
1 stop29h 20m
Frontier
Sun 3/294:15 pm
MIA
- SAN
1 stop11h 01m
Frontier
Deal found 3/26![Frontier logo]()
$385
This Expedia deal was found by Cheapflights users on 3/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Expedia is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 3/296:55 am
SAN
- MIA
1 stop13h 59m
Frontier
Tue 3/315:50 am
MIA
- SAN
1 stop21h 18m
Frontier
Deal found 3/25![Frontier logo]()
$375
This CheapOair deal was found by Cheapflights users on 3/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure CheapOair is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 3/296:55 am
SAN
- MIA
1 stop13h 59m
Frontier
Sun 4/55:50 am
MIA
- SAN
1 stop17h 36m
Frontier
Deal found 3/26![Frontier logo]()
$381
This Expedia deal was found by Cheapflights users on 3/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Expedia is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 3/309:00 am
SAN
- MIA
1 stop17h 38m
Frontier
Sun 4/55:50 am
MIA
- SAN
1 stop21h 12m
Frontier
Deal found 3/28![Frontier logo]()
$370
This Expedia deal was found by Cheapflights users on 3/24. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Expedia is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 4/16:25 am
SAN
- MIA
1 stop20h 24m
Frontier
Sun 4/512:59 pm
MIA
- SAN
1 stop13h 27m
Frontier
Deal found 3/24![Frontier logo]()
$386
This CheapOair deal was found by Cheapflights users on 3/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure CheapOair is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 4/28:47 am
SAN
- MIA
1 stop18h 02m
Frontier
Sun 4/512:59 pm
MIA
- SAN
1 stop13h 27m
Frontier
Deal found 3/25![Frontier logo]()
$380
This Super.com deal was found by Cheapflights users on 3/24. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Super.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 4/98:47 am
SAN
- MIA
1 stop18h 02m
Frontier
Sun 4/1212:59 pm
MIA
- SAN
1 stop13h 27m
Frontier
Deal found 3/24![Frontier logo]()
$372
This Southwest deal was found by Cheapflights users on 3/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 4/149:35 pm
SAN
- MIA
2 stops10h 55m
Southwest
Mon 4/201:50 pm
MIA
- SAN
2 stops11h 05m
Southwest
Deal found 3/27![Southwest logo]()
$383
This American Airlines deal was found by Cheapflights users on 3/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 4/2512:53 pm
SAN
- MIA
Nonstop5h 06m
American Airlines
Tue 4/287:50 pm
MIA
- SAN
Nonstop5h 38m
American Airlines
Deal found 3/26![American Airlines logo]()
$379
This Southwest deal was found by Cheapflights users on 3/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 4/279:35 am
SAN
- MIA
2 stops9h 25m
Southwest
Wed 5/63:00 pm
MIA
- SAN
2 stops9h 30m
Southwest
Deal found 3/26![Southwest logo]()
$373
This Southwest deal was found by Cheapflights users on 3/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 4/3010:40 pm
SAN
- MIA
2 stops15h 50m
Southwest
Tue 5/53:00 pm
MIA
- SAN
2 stops9h 30m
Southwest
Deal found 3/26![Southwest logo]()
$378
One-way flights from San Diego to Key LargoSearch for one-way flight options from San Diego to Key Largo. Find affordable one-way fares based on user searches. Data last updated March 29, 2026.
Search for one-way flight options from San Diego to Key Largo. Find affordable one-way fares based on user searches. Data last updated March 29, 2026.
This Kiwi.com deal was found by Cheapflights users on 3/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 5/16:36 pm
SAN
- MIA
3 stops23h 56m
Multiple Airlines
Deal found 3/28![Multiple Airlines logo]()
$208
This Kiwi.com deal was found by Cheapflights users on 3/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 5/264:17 pm
SAN
- MIA
3 stops19h 27m
Multiple Airlines
Deal found 3/28![Multiple Airlines logo]()
$211
This Super.com deal was found by Cheapflights users on 3/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Super.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 5/229:37 am
SAN
- MIA
1 stop16h 56m
Frontier
Deal found 3/25![Frontier logo]()
$212
This Kiwi.com deal was found by Cheapflights users on 3/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 4/269:00 pm
SAN
- MIA
3 stops15h 00m
Multiple Airlines
Deal found 3/28![Multiple Airlines logo]()
$215
This Expedia deal was found by Cheapflights users on 3/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Expedia is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 7/29:37 am
SAN
- MIA
1 stop17h 17m
Frontier
Deal found 3/26![Frontier logo]()
$216
This Kiwi.com deal was found by Cheapflights users on 3/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 7/39:53 pm
SAN
- MIA
1 stop30h 23m
Frontier
Deal found 3/26![Frontier logo]()
$217
This Kiwi.com deal was found by Cheapflights users on 3/24. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 6/244:17 pm
SAN
- MIA
2 stops10h 37m
Frontier
Deal found 3/24![Frontier logo]()
$218
This Southwest deal was found by Cheapflights users on 3/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 4/226:45 am
SAN
- MIA
1 stop7h 45m
Southwest
Deal found 3/26![Southwest logo]()
$219
This Kiwi.com deal was found by Cheapflights users on 3/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 9/39:53 pm
SAN
- MIA
1 stop30h 23m
Frontier
Deal found 3/25![Frontier logo]()
$221
This CheapOair deal was found by Cheapflights users on 3/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure CheapOair is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 7/199:37 am
SAN
- MIA
1 stop17h 17m
Frontier
Deal found 3/25![Frontier logo]()
$222
This Kiwi.com deal was found by Cheapflights users on 3/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 4/46:25 am
SAN
- MIA
3 stops24h 57m
Multiple Airlines
Deal found 3/28![Multiple Airlines logo]()
$223
This Southwest deal was found by Cheapflights users on 3/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 5/1410:40 pm
SAN
- MIA
2 stops11h 30m
Southwest
Deal found 3/27![Southwest logo]()
$224
Find flight deals from San Diego to Key Largo
Keep the following information in mind while searching for San Diego to Key Largo flight deals. Data was last updated March 29, 2026.
Most accurate provider | FlightHub 3 stars |
|---|---|
Most trusted provider | FlightHub 3 stars |
Round-trip from | $370 (Expedia) |
One-way from | $208 (Kiwi.com) |
Popular in | December |
Cheapest in | January |
Average price | $477 |
Cheapflights Fare Finder
Customize your flight search to find flights from San Diego to Key Largo that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated March 29, 2026.
Use the filters below to find and compare flights from San Diego to Key Largo that are best for you.
Fly from
Fly to
Route
Depart
Return
Cheapest round-trip
San DiegoMiami
SAN - MIA
SANMIA
San Diego
Mon 4/27
6:55 am-6:25 pm
2 stops8h 30m
Miami
Wed 5/6
12:10 pm-7:55 pm
2 stops10h 45m
$373
San DiegoMiami
SAN - MIA
SANMIA
San Diego
Sun 4/19
6:20 am-7:15 pm
2 stops9h 55m
Miami
Tue 4/28
3:00 pm-9:30 pm
2 stops9h 30m
$409
Quickest round-trip
San DiegoMiami
SAN - MIA
SANMIA
San Diego
Sat 4/18
6:25 am-4:05 pm
1 stop6h 40m
Miami
Sat 4/18
5:40 pm-9:45 pm
1 stop7h 05m
$437
San DiegoMiami
SAN - MIA
SANMIA
San Diego
Sun 8/9
7:50 pm-11:25 am
2 stops12h 35m
Miami
Sat 8/15
2:15 pm-6:25 pm
1 stop7h 10m
$437
San DiegoMiami
SAN - MIA
SANMIA
San Diego
Wed 4/22
6:25 am-6:06 pm
1 stop8h 41m
Miami
Tue 4/28
6:42 am-12:08 pm
1 stop8h 26m
$440
San DiegoMiami
SAN - MIA
SANMIA
San Diego
Sat 8/1
10:40 pm-2:30 pm
1 stop12h 50m
Miami
Fri 8/7
5:45 am-11:15 am
2 stops8h 30m
$443
San DiegoMiami
SAN - MIA
SANMIA
San Diego
Sat 8/1
10:40 pm-2:30 pm
1 stop12h 50m
Miami
Sat 8/8
7:00 am-2:35 pm
2 stops10h 35m
$443
San DiegoMiami
SAN - MIA
SANMIA
San Diego
Sat 6/6
6:25 am-11:00 pm
2 stops13h 35m
Miami
Fri 6/12
3:20 pm-9:05 pm
2 stops8h 45m
$448
San DiegoMiami
SAN - MIA
SANMIA
San Diego
Thu 5/28
7:55 am-11:00 pm
2 stops12h 05m
Miami
Fri 5/29
5:30 am-12:10 pm
2 stops9h 40m
$461
San DiegoMiami
SAN - MIA
SANMIA
San Diego
Thu 7/30
12:59 pm-11:39 pm
1 stop7h 40m
Miami
Sun 8/2
8:20 am-3:09 pm
1 stop9h 49m
$465
Showing 1-10 of 20 resultsSorted by cheapest first
Best time to book a flight from San Diego to Key Largo
Have a flexible travel schedule? Discover the best time to fly to Key Largo from San Diego with our price prediction graph.
SAN-MIA
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.
Cheapflights Insights
Everything you need to know about your flight from San Diego to Key Largo
SAN-KE9
SAN-MIA
How far ahead should I book a flight from San Diego to Key Largo?
Use this chart to determine the optimal time to book a round-trip flight from San Diego to Key Largo. Price data was last updated on March 13, 2026.
Booking 81 days in advance of your planned departure date is, on average, the best time to get cheap flights from San Diego to Key Largo. The general trend is that the closer you book to the departure date, the more expensive your flight will be.
What is the cheapest month to book a flight from San Diego to Key Largo?
Currently, May is the cheapest month in which you can book a flight from San Diego to Key Largo (average of $95). Flying from San Diego to Key Largo in February is currently the most expensive (average of $217). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.
What is the cheapest time of day to fly from SAN to KE9?
Find hourly flight availability from San Diego to Key Largo. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated March 29, 2026.
It’s optimal to fly from San Diego to Key Largo in the afternoon. By choosing this option you can save up to 31% on the cost of your flight, compared to a flight at noon.
What is the cheapest day to fly from San Diego to Key Largo?
Use this chart to determine the cheapest time to fly round-trip from San Diego to Key Largo. Price data was last updated on March 23, 2026.
Travelers seeking maximum savings on their San Diego to Key Largo flight should consider departing on Tuesday afternoons when fares are most often at their lowest. Saturday afternoons flights should be avoided if possible as fares are typically the most expensive at this time.
Weekly flight availability from San Diego to Key Largo
Explore weekly flight availability from San Diego to Key Largo. Discover flights operating on different days of the week, giving you the flexibility to choose a travel day that best fits your plans. Compare info to find the most convenient option for your journey. Data last updated March 29, 2026.
The most flights from SAN to KE9 are scheduled on a Saturday (6 on average). You will have fewer flight options on Wednesday, which is when the least amount of flights are scheduled (4 on average).
How much does it cost to fly round-trip from San Diego to Key Largo?
Reviews of airlines servicing Key Largo
Get insights into the airlines that provide service to Key Largo. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Key Largo. Reviews last updated March 29, 2026.
See what other customers who have flown with Southwest,Alaska Airlines, andDelta from San Diego to Key Largo have to say. You can also see how each airline compares in terms of entertainment options, comfort, food, crew/service, and boarding process.
Boarding
8.1
Entertainment
7.5
Comfort
8.0
Overall
8.0
Food
7.0
Crew
8.6
Reviews
1 / 20
6.0
GoodScott,Feb 2026
HOU - FLL
Boarding
8.1
Entertainment
7.5
Comfort
8.0
Overall
8.0
Food
7.0
Crew
8.6
Reviews
1 / 20
6.0
GoodScott,Feb 2026
HOU - FLL
Boarding
8.1
Entertainment
7.5
Comfort
8.0
Overall
8.0
Food
7.0
Crew
8.6
Reviews
1 / 20
6.0
GoodScott,Feb 2026
HOU - FLL
Boarding
8.1
Entertainment
7.5
Comfort
8.0
Overall
8.0
Food
7.0
Crew
8.6
Reviews
1 / 20
6.0
GoodScott,Feb 2026
HOU - FLL
Boarding
8.1
Entertainment
7.5
Comfort
8.0
Overall
8.0
Food
7.0
Crew
8.6
Reviews
1 / 20
6.0
GoodScott,Feb 2026
HOU - FLL
Boarding
8.1
Entertainment
7.5
Comfort
8.0
Overall
8.0
Food
7.0
Crew
8.6
Reviews
1 / 20
6.0
GoodScott,Feb 2026
HOU - FLL
Related info for your journey
Find useful and relevant information for your journey from San Diego to Key Largo. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.
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Alternative routes for San Diego to Key Largo
See prices for flight routes from nearby airports that may be better suited for you.
Complete your trip
Complete your trip to Key Largo by adding a car rental and/or hotel reservation to your travel itinerary.
Search flights from San Diego to Key Largo by cabin class
Find flights from San Diego to Key Largo, based on your preferred cabin class, be it economy, premium economy, business, or first class.
San Diego and Key Largo flights
Browse other San Diego and Key Largo flight options. Last updated on March 29, 2026.
Other flights from San Diego
Browse through other flights departing from San Diego. Flights are based on user searches made on Cheapflights and were last updated on March 29, 2026.
Popular flight searches
Check out other popular destinations found by fellow travelers in 2026
San Diego to Key Largo flights
Consider these flights traveling from San Diego to Key Largo.
Top 8 airlines flying from San Diego to Key Largo
Discover the top 8 airlines that operate flights from San Diego to Key Largo. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated March 29, 2026.
| Airline | Cheapest | Average | Flexibility | On-time |
|---|---|---|---|---|
| Cheapest$86 | Average$235 | FlexibilityNo cancel fee | On-time62% | |
| Cheapest$121 | Average$216 | FlexibilityNo cancel fee | On-time65% | |
| Cheapest$180 | Average$425 | FlexibilityNo cancel fee | On-time71% | |
| Cheapest$194 | Average$299 | FlexibilityNo cancel fee | On-time85% | |
| Cheapest$206 | Average$376 | FlexibilityNo cancel fee | On-timeN/A | |
| Cheapest$217 | Average$505 | FlexibilityNo cancel fee | On-time75% | |
| Cheapest$218 | Average$444 | FlexibilityNo cancel fee | On-time63% | |
| Cheapest$237 | Average$382 | FlexibilityNo cancel fee | On-time69% |