HomeSearch by dateVacation packagesHotelsFlight dealsCar rentalTravel tips & news
Key Largo

$109+ Cheap flights from Portland, ME (PWM) to Key Largo, FL

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 1/18. Fares are subject to change and may not be available on all flights or dates of travel.
PWM — MIA
Nov 27 — Dec 41
Thu 11/27
Thu 12/4
1 adult, Economy
We work with more than 300 partners to bring you better travel deals

Find cheap flights from Portland to Key Largo with Cheapflights

1. Tell us where you want to go

Enter your travel information like dates, passengers, trip type (one-way or round trip), and preferred cabin class then click “Find deals”

2. Select your favorite providers

We find the providers serving your travel needs. Choose up to four travel providers to compare side-by-side for flights, hotels, or car rentals.

3. Compare prices and book

Review each provider’s pricing and select the best option for you! Book through your favorite provider’s website for a seamless experience.

Cheapflights Tip: The best prices from Portland to Key Largo are usually found in September or August, booked 39 days in advance, depart on a Wednesday or Tuesday and return on a Tuesday

Cheap flight deals from Portland to Key Largo

Keep the following information in mind while searching for Portland to Key Largo flight deals. Data was last updated October 28, 2025.

Most accurate provider

eDreams
3 stars

Most trusted provider

eDreams
3 stars

Round-trip from

$217
(American Airlines)

One-way from

$109
(American Airlines)

Popular in

July

Cheapest in

September

Average price

$388
Provider with most accurate pricing for Portland-Miami flight deals.
Search Deals
Provider most trusted by Cheapflights users for Portland-Miami flights.
Search Deals
From Portland to Key Largo
Search Deals
One-way flight from Portland to Key Largo
Search Deals
Highest demand for flights based on searches. 0% potential increase in price ($2 potential increase over avg. RT price).
Search Deals
Cheapest flight prices on average. 3% potential price decrease ($12 potential savings vs. average RT price).
Search Deals
Average for round-trip flights in October 2025
Search Deals

Find flight deals from Portland to Key Largo

Cheapest flights from Portland to Key Largo
Explore the most affordable flight options available from Portland to Key Largo. Find the lowest fares from popular airlines and budget airlines, with prices last updated on October 28, 2025.

This American Airlines deal was found by Cheapflights users on 10/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 11/167:02 amPWM - MIA
1 stop8h 19mAmerican Airlines
Tue 11/1810:01 amMIA - PWM
1 stop6h 40mAmerican Airlines
Deal found 10/27$217
This Delta deal was found by Cheapflights users on 10/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 12/612:12 pmPWM - MIA
1 stop6h 38mDelta
Sat 12/133:30 pmMIA - PWM
1 stop5h 21mDelta
Deal found 10/27$218
This Delta deal was found by Cheapflights users on 10/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 11/106:00 amPWM - MIA
1 stop8h 20mDelta
Sat 11/156:00 amMIA - PWM
1 stop6h 30mDelta
Deal found 10/26$248
This United Airlines deal was found by Cheapflights users on 10/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 11/256:00 amPWM - MIA
1 stop5h 37mUnited Airlines
Tue 12/25:50 pmMIA - PWM
1 stop5h 19mUnited Airlines
Deal found 10/26$252
This Delta deal was found by Cheapflights users on 10/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 11/144:53 pmPWM - MIA
2 stops24h 21mDelta
Thu 11/207:15 amMIA - PWM
1 stop6h 35mDelta
Deal found 10/26$276
This Delta deal was found by Cheapflights users on 10/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 11/106:00 amPWM - MIA
1 stop8h 35mDelta
Fri 11/144:52 pmMIA - PWM
1 stop5h 27mDelta
Deal found 10/26$278
This American Airlines deal was found by Cheapflights users on 10/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 11/85:21 pmPWM - MIA
2 stops7h 25mAmerican Airlines
Sat 11/156:40 amMIA - PWM
1 stop5h 33mAmerican Airlines
Deal found 10/27$295
This United Airlines deal was found by Cheapflights users on 10/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 11/106:00 amPWM - MIA
1 stop5h 37mUnited Airlines
Fri 11/147:00 amMIA - PWM
1 stop7h 12mUnited Airlines
Deal found 10/26$297
This United Airlines deal was found by Cheapflights users on 10/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 12/116:00 amPWM - MIA
1 stop8h 41mUnited Airlines
Tue 12/1612:23 pmMIA - PWM
2 stops10h 46mUnited Airlines
Deal found 10/26$298
This American Airlines deal was found by Cheapflights users on 10/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 12/55:17 pmPWM - MIA
1 stop5h 39mAmerican Airlines
Mon 12/88:20 amMIA - PWM
1 stop7h 07mAmerican Airlines
Deal found 10/27$299

Cheapflights Fare Finder

 
Customize your flight search to find flights from Portland to Key Largo that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated October 28, 2025.
Use the filters below to find and compare flights from Portland to Key Largo that are best for you.

Fly from

Portland

Fly to

Key Largo

Route

Depart

Return

Price

PortlandMiami

PWM - MIA

PWMMIA

Portland

Tue 11/25

6:00 am-11:37 am

1 stop5h 37m

Miami

Tue 12/2

5:50 pm-11:09 pm

1 stop5h 19m

$252

PortlandMiami

PWM - MIA

PWMMIA

Portland

Fri 11/14

4:53 pm-5:14 pm

2 stops24h 21m

Miami

Thu 11/20

7:15 am-1:50 pm

1 stop6h 35m

$276

PortlandMiami

PWM - MIA

PWMMIA

Portland

Sat 11/8

5:21 pm-12:46 am

2 stops7h 25m

Miami

Sat 11/15

6:40 am-12:13 pm

1 stop5h 33m

$295

PortlandMiami

PWM - MIA

PWMMIA

Portland

Mon 11/10

6:00 am-11:37 am

1 stop5h 37m

Miami

Fri 11/14

7:00 am-2:12 pm

1 stop7h 12m

$297

PortlandMiami

PWM - MIA

PWMMIA

Portland

Fri 12/5

5:17 pm-10:56 pm

1 stop5h 39m

Miami

Mon 12/8

8:20 am-3:27 pm

1 stop7h 07m

$299

PortlandMiami

PWM - MIA

PWMMIA

Portland

Sun 11/16

5:30 am-2:51 pm

2 stops9h 21m

Miami

Tue 11/18

11:00 am-6:59 pm

2 stops7h 59m

$319

PortlandMiami

PWM - MIA

PWMMIA

Portland

Thu 12/4

12:53 pm-9:50 pm

1 stop8h 57m

Miami

Sat 12/13

5:20 pm-11:59 pm

1 stop6h 39m

$338

PortlandMiami

PWM - MIA

PWMMIA

Portland

Sun 11/9

6:00 am-1:02 pm

1 stop7h 02m

Miami

Sat 11/15

6:00 am-12:30 pm

1 stop6h 30m

$338

PortlandMiami

PWM - MIA

PWMMIA

Portland

Wed 11/12

3:20 pm-11:04 pm

1 stop7h 44m

Miami

Sun 11/16

7:00 am-2:12 pm

1 stop7h 12m

$356

PortlandMiami

PWM - MIA

PWMMIA

Portland

Fri 11/28

5:30 am-11:14 am

1 stop5h 44m

Miami

Fri 12/5

4:36 pm-11:09 pm

1 stop6h 33m

$359

Flights are sorted by cheapest round-trip flights first.

Deals found on 10/26

Showing 1-10 of 19 results
1
2

Best time to book a flight from Portland to Key Largo

Have a flexible travel schedule? Discover the best time to fly to Key Largo from Portland with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Portland to Key Largo

How far ahead should I book a flight from Portland, Maine to Key Largo?

Use this chart to determine the optimal time to book a round-trip flight from Portland to Key Largo. Price data was last updated on October 24, 2025.

Booking 39 days in advance of your planned departure date is, on average, the best time to get cheap flights from Portland, Maine to Key Largo. The general trend is that the closer you book to the departure date, the more expensive your flight will be.

What is the cheapest month to book a flight from Portland, Maine to Key Largo?

Currently, January is the cheapest month in which you can book a flight from Portland, Maine to Key Largo (average of $41). Flying from Portland, Maine to Key Largo in August is currently the most expensive (average of $94). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

What is the cheapest time of day to fly from PWM to KE9?

Find hourly flight availability from Portland to Key Largo. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated October 28, 2025.

A simple way to save on the total cost of your ticket is to fly from Portland, Maine to Key Largo in the afternoon. If you’re flexible enough to do this you can expect to save up to 11% on your trip compared to booking a flight in the evening.

Reviews of airlines servicing Key Largo

Get insights into the airlines that provide service to Key Largo. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Key Largo. Reviews last updated October 28, 2025.
Read reviews from past customers who have flown Southwest, Delta, and United Airlines from Portland to Key Largo. Users can see the overall rating for each airline as well as how each is rated in terms of entertainment options, comfort, food, crew/service, and boarding process.
Southwest
8.0
Very good
4,240 reviews

Overall

8.0

Comfort

8.0

Entertainment

7.5

Food

7.0

Boarding

8.1

Crew

8.6

Reviews

1 / 20
2.0
Mediocre

Mike,Aug 2025

OKC - AUS

AC was not adequate, even on a night flight. WiFi subpar even for the airlines
Southwest
8.0
Very good
4,240 reviews
Southwest
8.0
Very good
4,240 reviews

Overall

8.0

Comfort

8.0

Entertainment

7.5

Food

7.0

Boarding

8.1

Crew

8.6

Reviews

1 / 20
2.0
Mediocre

Mike,Aug 2025

OKC - AUS

AC was not adequate, even on a night flight. WiFi subpar even for the airlines
Delta
7.9
Good
7,994 reviews
Southwest
8.0
Very good
4,240 reviews

Overall

8.0

Comfort

8.0

Entertainment

7.5

Food

7.0

Boarding

8.1

Crew

8.6

Reviews

1 / 20
2.0
Mediocre

Mike,Aug 2025

OKC - AUS

AC was not adequate, even on a night flight. WiFi subpar even for the airlines
United Airlines
7.4
Good
9,001 reviews
Southwest
8.0
Very good
4,240 reviews

Overall

8.0

Comfort

8.0

Entertainment

7.5

Food

7.0

Boarding

8.1

Crew

8.6

Reviews

1 / 20
2.0
Mediocre

Mike,Aug 2025

OKC - AUS

AC was not adequate, even on a night flight. WiFi subpar even for the airlines
American Airlines
7.2
Good
11,032 reviews
Southwest
8.0
Very good
4,240 reviews

Overall

8.0

Comfort

8.0

Entertainment

7.5

Food

7.0

Boarding

8.1

Crew

8.6

Reviews

1 / 20
2.0
Mediocre

Mike,Aug 2025

OKC - AUS

AC was not adequate, even on a night flight. WiFi subpar even for the airlines
JetBlue
7.2
Good
2,908 reviews
Southwest
8.0
Very good
4,240 reviews

Overall

8.0

Comfort

8.0

Entertainment

7.5

Food

7.0

Boarding

8.1

Crew

8.6

Reviews

1 / 20
2.0
Mediocre

Mike,Aug 2025

OKC - AUS

AC was not adequate, even on a night flight. WiFi subpar even for the airlines

Related info for your journey

Find useful and relevant information for your journey from Portland to Key Largo. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • What airport do you fly from for flights from Portland to Key Largo?

    Located just 2.9 mi from the city center, Portland is the airport most travelers will use when flying to Key Largo from Portland. Booking flights from Portland (PWM) to Key Largo should be relatively easy as there are 0 daily outbound flights to Key Largo from 5 different airlines.

  • How popular is this Portland, Maine to Key Largo flight route?

    Within the past month, 1 users have taken a look at flights from Portland to Key Largo.

  • How long is the flight from Portland, Maine to Key Largo?

    A quick flight from Portland, Maine to Key Largo can take about 5h 37m. United Airlines provides one of the quickest options available for as low as $252. Airlines will cover a distance of 1354 mi. Both multi-stop and nonstop flights can be found to your destination and back.

  • Can I find deals for flights from Portland to Key Largo that include hotel bookings?

    Yes. In addition to deals on Portland to Key Largo flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Portland to Key Largo?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Portland to Key Largo.

  • Can I find deals for business class flights from Portland to Key Largo?

    Yes. Cheapflights offers flight deals from Portland to Key Largo by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Portland, Maine to Key Largo?

    Currently, January is the cheapest month in which you can book a flight from Portland, Maine to Key Largo (average of $41). Flying from Portland, Maine to Key Largo in August is currently the most expensive (average of $94). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

Browse thousands of different options on Cheapflights for your next trip

Toggle through the tabs below to find thousands of options on Cheapflights for your next trip.

Alternative routes for Portland to Key Largo

See prices for flight routes from nearby airports that may be better suited for you.
Boston to Orlando flights
Boston to Miami flights
Boston to Tampa flights
Boston to Fort Lauderdale flights
Boston to West Palm Beach flights
Boston to Fort Myers flights
Boston to Sarasota flights
Boston to Jacksonville flights
Boston to Key West flights
Boston to St Petersburg flights
Boston to Orlando Sanford Intl flights
Portland to Orlando flights
Boston to Daytona Beach flights
Boston to Pensacola flights
Portland to Fort Lauderdale flights
Bangor to St Petersburg flights
Portland to Tampa flights
Bangor to Orlando Sanford Intl flights
Portland to West Palm Beach flights
Boston to Panama City flights
Boston to Melbourne flights
Portland to Miami flights
Portland to Fort Myers flights
Boston to Valparaiso flights
Portland to Jacksonville flights
Bangor to Tampa flights
Bangor to Orlando flights
Bangor to Miami flights
Portland to Key West flights
Portland to Sarasota flights
Boston to Tallahassee flights
Bangor to Fort Lauderdale flights
Boston to Gainesville flights
Bangor to Fort Myers flights
Bangor to West Palm Beach flights
Bangor to Pensacola flights
Portland to Panama City flights
Portland to Pensacola flights
Portland to Daytona Beach flights
Portland to Melbourne flights
Bangor to Sarasota flights
Boston to Punta Gorda flights
Bangor to Jacksonville flights
Bangor to Key West flights
Augusta to Fort Myers flights
Portland to Valparaiso flights
Augusta to Tampa flights
Augusta to Orlando flights
Portland to Tallahassee flights
Rockland to Fort Myers flights

Top 5 airlines flying from Portland to Key Largo

Discover the top 5 airlines that operate flights from Portland to Key Largo. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated October 28, 2025.
AirlineCheapestAverageFlexibilityOn-time
DeltaCheapest$118Average$343FlexibilityNo cancel feeOn-timeN/A
JetBlueCheapest$194Average$289FlexibilityNo cancel feeOn-time62%
United AirlinesCheapest$212Average$457FlexibilityNo cancel feeOn-time69%
American AirlinesCheapest$216Average$414FlexibilityNo cancel feeOn-time71%
SouthwestCheapest$226Average$499FlexibilityNo cancel feeOn-time63%

100% Free

Cheapflights is completely free to use, so you can start saving the moment you arrive.

Book with Flexibility

Our users can plan ahead with confidence and find flights with no change fees

Travel Smart

Millions of people come to us for their flight needs every year. We help make travel planning easy by providing useful insights and data-driven graphs that can inform your decisions.