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Key Largo

$83+ Cheap flights from Myrtle Beach (MYR) to Key Largo, FL

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 5/3. Fares are subject to change and may not be available on all flights or dates of travel.
MYR — MIA
May 9 — May 161
Sat 5/9
Sat 5/16
1 adult, Economy
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Cheap flight deals from Myrtle Beach to Key Largo

Cheapest flights from Myrtle Beach to Key Largo
Explore the most affordable flight options available from Myrtle Beach to Key Largo. Find the lowest fares from popular airlines and budget airlines, with prices last updated on April 9, 2026.

This Frontier deal was found by Cheapflights users on 4/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Frontier is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 4/273:09 pm
MYR
-
MIA
1 stop7h 25m
Frontier
Fri 5/17:00 am
MIA
-
MYR
1 stop9h 44m
Frontier
Deal found 4/6$140
This CheapOair deal was found by Cheapflights users on 4/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure CheapOair is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 5/15:29 pm
MYR
-
MIA
1 stop21h 40m
Frontier
Mon 5/47:00 am
MIA
-
MYR
1 stop9h 44m
Frontier
Deal found 4/6$151
This Frontier deal was found by Cheapflights users on 4/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Frontier is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 5/15:29 pm
MYR
-
MIA
1 stop21h 40m
Frontier
Sun 5/36:15 am
MIA
-
MYR
1 stop10h 29m
Frontier
Deal found 4/5$161
This CheapOair deal was found by Cheapflights users on 4/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure CheapOair is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 4/245:29 pm
MYR
-
MIA
1 stop21h 40m
Frontier
Mon 4/277:00 am
MIA
-
MYR
1 stop9h 44m
Frontier
Deal found 4/4$171
This Priceline deal was found by Cheapflights users on 4/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Priceline is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 4/203:39 pm
MYR
-
MIA
1 stop6h 55m
Frontier
Fri 4/247:00 am
MIA
-
MYR
1 stop9h 44m
Frontier
Deal found 4/5$180
This CheapOair deal was found by Cheapflights users on 4/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure CheapOair is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 4/235:29 pm
MYR
-
MIA
1 stop20h 38m
Frontier
Sun 4/266:15 am
MIA
-
MYR
1 stop10h 29m
Frontier
Deal found 4/6$191
This CheapOair deal was found by Cheapflights users on 4/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure CheapOair is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 4/254:45 pm
MYR
-
MIA
1 stop23h 37m
Spirit Airlines
Fri 5/15:49 pm
MIA
-
MYR
1 stop22h 01m
Spirit Airlines
Deal found 4/5$192
This CheapOair deal was found by Cheapflights users on 4/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure CheapOair is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 4/258:43 pm
MYR
-
MIA
1 stop19h 39m
Spirit Airlines
Thu 4/304:05 pm
MIA
-
MYR
1 stop22h 39m
Spirit Airlines
Deal found 4/6$193
This Frontier deal was found by Cheapflights users on 4/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Frontier is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 4/203:39 pm
MYR
-
MIA
1 stop6h 55m
Frontier
Thu 4/237:00 am
MIA
-
MYR
1 stop9h 44m
Frontier
Deal found 4/8$201
This Mytrip deal was found by Cheapflights users on 4/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Mytrip is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 4/218:43 pm
MYR
-
MIA
1 stop16h 21m
Spirit Airlines
Wed 4/225:49 pm
MIA
-
MYR
1 stop14h 24m
Spirit Airlines
Deal found 4/7$204

Find flight deals from Myrtle Beach to Key Largo

Keep the following information in mind while searching for Myrtle Beach to Key Largo flight deals. Data was last updated April 9, 2026.

Most accurate provider

FlightHub
3 stars

Most trusted provider

FlightHub
3 stars

Round-trip from

$140
(Frontier)

One-way from

$83
(Kiwi.com)

Popular in

February

Cheapest in

August

Average price

$380
Provider with most accurate pricing for Myrtle Beach Intl-Miami flight deals.
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Provider most trusted by Cheapflights users for Myrtle Beach Intl-Miami flights.
Search Deals
From Myrtle Beach Intl to Key Largo
Search Deals
One-way flight from Myrtle Beach Intl to Key Largo
Search Deals
Highest demand for flights based on searches. 11% potential increase in price ($46 potential increase over avg. RT price).
Search Deals
Cheapest flight prices on average. 2% potential price decrease ($8 potential savings vs. average RT price).
Search Deals
Average for round-trip flights in April 2026
Search Deals

Cheapflights Fare Finder

 
Customize your flight search to find flights from Myrtle Beach to Key Largo that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated April 9, 2026.
Use the filters below to find and compare flights from Myrtle Beach to Key Largo that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

Cheapest round-trip

Myrtle BeachMiami

MYR - MIA

MYRMIA

Myrtle Beach Intl

Mon 5/4

9:39 pm-1:04 pm

1 stop15h 25m

Miami

Mon 5/11

9:33 am-2:48 pm

2 stops29h 15m

$231

Myrtle BeachMiami

MYR - MIA

MYRMIA

Myrtle Beach Intl

Sat 5/9

6:30 am-1:04 pm

3 stops30h 34m

Miami

Mon 5/11

9:33 am-9:14 am

2 stops23h 41m

$358

Myrtle BeachMiami

MYR - MIA

MYRMIA

Myrtle Beach Intl

Wed 5/6

2:10 pm-9:55 pm

2 stops7h 45m

Miami

Wed 5/13

7:00 am-3:25 pm

2 stops8h 25m

$365

Myrtle BeachMiami

MYR - MIA

MYRMIA

Myrtle Beach Intl

Mon 4/27

3:45 pm-9:25 pm

1 stop5h 40m

Miami

Fri 5/1

6:40 am-6:45 pm

2 stops12h 05m

$385
Quickest round-trip

Myrtle BeachMiami

MYR - MIA

MYRMIA

Myrtle Beach Intl

Mon 4/27

3:45 pm-10:00 pm

2 stops6h 15m

Miami

Thu 4/30

1:50 pm-8:50 pm

2 stops7h 00m

$390

Myrtle BeachMiami

MYR - MIA

MYRMIA

Myrtle Beach Intl

Thu 5/7

3:45 pm-10:00 pm

2 stops6h 15m

Miami

Thu 5/14

6:40 am-6:45 pm

2 stops12h 05m

$410

Myrtle BeachMiami

MYR - MIA

MYRMIA

Myrtle Beach Intl

Sun 6/21

10:30 am-10:05 pm

2 stops11h 35m

Miami

Sat 6/27

6:20 am-4:10 pm

2 stops9h 50m

$453

Myrtle BeachMiami

MYR - MIA

MYRMIA

Myrtle Beach Intl

Fri 6/26

11:55 am-10:05 pm

2 stops10h 10m

Miami

Mon 6/29

5:35 am-6:35 pm

2 stops13h 00m

$474

Myrtle BeachMiami

MYR - MIA

MYRMIA

Myrtle Beach Intl

Sat 4/18

3:15 pm-10:45 pm

1 stop7h 30m

Miami

Mon 5/18

7:40 pm-10:42 am

1 stop15h 02m

$540

Myrtle BeachMiami

MYR - MIA

MYRMIA

Myrtle Beach Intl

Tue 4/21

3:15 pm-10:45 pm

1 stop7h 30m

Miami

Sat 4/25

9:30 am-5:09 pm

1 stop7h 39m

$547

Flights are sorted by cheapest round-trip flights first.

Deals found on 4/8

Showing 1-10 of 20 resultsSorted by cheapest first
1
2

Best time to book a flight from Myrtle Beach to Key Largo

Have a flexible travel schedule? Discover the best time to fly to Key Largo from Myrtle Beach with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Myrtle Beach to Key Largo

How far ahead should I book a flight from Myrtle Beach to Key Largo?

Use this chart to determine the optimal time to book a round-trip flight from Myrtle Beach to Key Largo. Price data was last updated on April 3, 2026.

To ensure you get the cheapest price possible for a flight from Myrtle Beach to Key Largo, you should look to book at least 68 days in advance of your intended travel date. The price of your flight may increase if you delay and leave booking until a week or so before departure.

What is the cheapest month to book a flight from Myrtle Beach to Key Largo?

Currently, December is the cheapest month in which you can book a flight from Myrtle Beach to Key Largo (average of $33). Flying from Myrtle Beach to Key Largo in June is currently the most expensive (average of $82). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

What is the cheapest time of day to fly from MYR to KE9?

Find hourly flight availability from Myrtle Beach to Key Largo. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated April 9, 2026.

Unlike in the morning, when flights are generally more expensive, you can save up to 21% on flights from Myrtle Beach to Key Largo by exploring options for tickets in the afternoon.

What is the cheapest day to fly from Myrtle Beach to Key Largo?

Use this chart to determine the cheapest time to fly round-trip from Myrtle Beach to Key Largo. Price data was last updated on April 4, 2026.

Travelers seeking maximum savings on their Myrtle Beach to Key Largo flight should consider departing on Tuesday at noon when fares are most often at their lowest. Monday evenings flights should be avoided if possible as fares are typically the most expensive at this time.

How much does it cost to fly round-trip from Myrtle Beach to Key Largo?

Reviews of airlines servicing Key Largo

Get insights into the airlines that provide service to Key Largo. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Key Largo. Reviews last updated April 9, 2026.
Get a feel of what it's like to fly with Delta,American Airlines, andSpirit Airlines from Myrtle Beach to Key Largo by reading reviews from past customers. Users have also rated airlines in terms of entertainment options, comfort, food, crew/service, and boarding process.
Delta
7.9
Good
8,392 reviews

Comfort

7.9

Entertainment

7.8

Food

7.2

Boarding

8.1

Crew

8.5

Overall

7.9

Reviews

1 / 20
8.0
Excellent

Matthew,Oct 2025

GSP - ATL

This is always a full flight since it is the connecting route to primary destinations through Atlanta. That said, the crew handles the full load well. Not much more to say, it is a short flight with no in-flight services due to the length.
Delta
7.9
Good
8,392 reviews
Delta
7.9
Good
8,392 reviews

Comfort

7.9

Entertainment

7.8

Food

7.2

Boarding

8.1

Crew

8.5

Overall

7.9

Reviews

1 / 20
8.0
Excellent

Matthew,Oct 2025

GSP - ATL

This is always a full flight since it is the connecting route to primary destinations through Atlanta. That said, the crew handles the full load well. Not much more to say, it is a short flight with no in-flight services due to the length.
American Airlines
7.1
Good
11,564 reviews
Delta
7.9
Good
8,392 reviews

Comfort

7.9

Entertainment

7.8

Food

7.2

Boarding

8.1

Crew

8.5

Overall

7.9

Reviews

1 / 20
8.0
Excellent

Matthew,Oct 2025

GSP - ATL

This is always a full flight since it is the connecting route to primary destinations through Atlanta. That said, the crew handles the full load well. Not much more to say, it is a short flight with no in-flight services due to the length.
Spirit Airlines
6.3
Okay
8,607 reviews
Delta
7.9
Good
8,392 reviews

Comfort

7.9

Entertainment

7.8

Food

7.2

Boarding

8.1

Crew

8.5

Overall

7.9

Reviews

1 / 20
8.0
Excellent

Matthew,Oct 2025

GSP - ATL

This is always a full flight since it is the connecting route to primary destinations through Atlanta. That said, the crew handles the full load well. Not much more to say, it is a short flight with no in-flight services due to the length.

Related info for your journey

Find useful and relevant information for your journey from Myrtle Beach to Key Largo. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • What airport do you fly from for flights from Myrtle Beach to Key Largo?

    If you book a flight to Key Largo from Myrtle Beach, you will be flying from Myrtle Beach Intl, which is the city’s only airport. Myrtle Beach Intl (MYR) is located 2.1 mi from the center of Myrtle Beach. There are 0 flights from Myrtle Beach Intl to Key Largo per day from 4 different airlines.

  • How long is the flight from Myrtle Beach to Key Largo?

    Spirit Airlines and Southwest can get you from Myrtle Beach to Key Largo in just under 7h 45m. Your travel time can differ by up to 7h 40m. The distance from Myrtle Beach to Key Largo is about 551 mi. When browsing for deals, the options you’ll see will be for both nonstop flights and flights with stops.

  • What are the cheapest airlines to fly from Myrtle Beach to Key Largo one-way?

    The cheapest airlines for a one-way flight from Myrtle Beach to Key Largo are Spirit Airlines ($45), American Airlines ($99), and Delta ($104).

  • Can I find deals for flights from Myrtle Beach to Key Largo that include hotel bookings?

    Yes. In addition to deals on Myrtle Beach to Key Largo flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Myrtle Beach to Key Largo?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Myrtle Beach to Key Largo.

  • Can I find deals for business class flights from Myrtle Beach to Key Largo?

    Yes. Cheapflights offers flight deals from Myrtle Beach to Key Largo by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Myrtle Beach to Key Largo?

    Currently, December is the cheapest month in which you can book a flight from Myrtle Beach to Key Largo (average of $33). Flying from Myrtle Beach to Key Largo in June is currently the most expensive (average of $82). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

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Top 4 airlines flying from Myrtle Beach to Key Largo

Discover the top 4 airlines that operate flights from Myrtle Beach to Key Largo. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated April 9, 2026.
AirlineCheapestAverageFlexibilityOn-time
Spirit AirlinesCheapest$95Average$171FlexibilityNo cancel feeOn-time65%
Breeze AirwaysCheapest$98Average$173FlexibilityNo cancel feeOn-timeN/A
DeltaCheapest$100Average$416FlexibilityNo cancel feeOn-timeN/A
American AirlinesCheapest$248Average$406FlexibilityNo cancel feeOn-time71%

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