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Key Largo

$74+ Cheap flights from Myrtle Beach (MYR) to Key Largo, FL

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 11/14. Fares are subject to change and may not be available on all flights or dates of travel.
MYR — MIA
Nov 29 — Dec 61
Sat 11/29
Sat 12/6
1 adult, Economy
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Cheapflights Tip: The best prices from Myrtle Beach Intl to Key Largo are usually found in October or August, booked 18 days in advance, depart on a Monday or Wednesday and return on a Monday

Find flight deals from Myrtle Beach to Key Largo

Cheapest flights from Myrtle Beach to Key Largo
Explore the most affordable flight options available from Myrtle Beach to Key Largo. Find the lowest fares from popular airlines and budget airlines, with prices last updated on October 30, 2025.

This Mytrip deal was found by Cheapflights users on 10/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Mytrip is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 11/152:46 pmMYR - MIA
2 stops20h 14mSpirit Airlines
Tue 11/187:39 pmMIA - MYR
1 stop14h 29mSpirit Airlines
Deal found 10/28$170
This Mytrip deal was found by Cheapflights users on 10/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Mytrip is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 11/1211:13 amMYR - MIA
2 stops23h 47mSpirit Airlines
Fri 11/1412:05 pmMIA - MYR
2 stops10h 21mSpirit Airlines
Deal found 10/29$183
This Mytrip deal was found by Cheapflights users on 10/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Mytrip is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 11/142:46 pmMYR - MIA
2 stops19h 12mSpirit Airlines
Sun 11/169:59 pmMIA - MYR
2 stops24h 27mSpirit Airlines
Deal found 10/29$190
This Kiwi.com deal was found by Cheapflights users on 10/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 11/142:46 pmMYR - MIA
2 stops30h 02mMultiple Airlines
Wed 11/196:25 amMIA - MYR
1 stop27h 40mMultiple Airlines
Deal found 10/28$191
This Mytrip deal was found by Cheapflights users on 10/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Mytrip is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 12/59:05 amMYR - MIA
1 stop5h 58mSpirit Airlines
Mon 12/88:53 pmMIA - MYR
1 stop11h 07mSpirit Airlines
Deal found 10/29$197
This Kiwi.com deal was found by Cheapflights users on 10/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 11/1912:30 pmMYR - MIA
1 stop9h 00mSpirit Airlines
Mon 11/248:20 pmMIA - MYR
1 stop17h 31mSpirit Airlines
Deal found 10/28$211
This Kiwi.com deal was found by Cheapflights users on 10/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 11/189:22 amMYR - MIA
1 stop23h 50mMultiple Airlines
Sat 11/229:40 pmMIA - MYR
1 stop16h 11mMultiple Airlines
Deal found 10/29$212

Cheap flight deals from Myrtle Beach to Key Largo

Keep the following information in mind while searching for Myrtle Beach to Key Largo flight deals. Data was last updated October 30, 2025.

Most accurate provider

eDreams
3 stars

Most trusted provider

eDreams
3 stars

Round-trip from

$183
(Mytrip)

One-way from

$74
(Mytrip)

Popular in

December

Cheapest in

October

Average price

$297
Provider with most accurate pricing for Myrtle Beach Intl-Miami flight deals.
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Provider most trusted by Cheapflights users for Myrtle Beach Intl-Miami flights.
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From Myrtle Beach Intl to Key Largo
Search Deals
One-way flight from Myrtle Beach Intl to Key Largo
Search Deals
Highest demand for flights based on searches. 3% potential increase in price ($13 potential increase over avg. RT price).
Search Deals
Cheapest flight prices on average. 1% potential price decrease ($7 potential savings vs. average RT price).
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Average for round-trip flights in October 2025
Search Deals

Cheapflights Fare Finder

 
Customize your flight search to find flights from Myrtle Beach to Key Largo that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated October 30, 2025.
Use the filters below to find and compare flights from Myrtle Beach to Key Largo that are best for you.

Fly from

Myrtle Beach

Fly to

Key Largo

Route

Depart

Return

Price

Myrtle BeachMiami

MYR - MIA

MYRMIA

Myrtle Beach Intl

Fri 11/14

2:46 pm-8:48 pm

2 stops30h 02m

Miami

Wed 11/19

6:25 am-10:05 am

1 stop27h 40m

$191

Myrtle BeachMiami

MYR - MIA

MYRMIA

Myrtle Beach Intl

Fri 12/5

9:05 am-11:21 pm

1 stop14h 16m

Miami

Sun 12/7

3:17 pm-1:20 pm

2 stops22h 03m

$218

Myrtle BeachMiami

MYR - MIA

MYRMIA

Myrtle Beach Intl

Fri 12/12

9:05 am-3:03 pm

1 stop5h 58m

Miami

Tue 12/16

12:36 pm-8:49 am

2 stops20h 13m

$223

Myrtle BeachMiami

MYR - MIA

MYRMIA

Myrtle Beach Intl

Fri 11/14

2:46 pm-9:58 am

2 stops19h 12m

Miami

Fri 11/21

6:46 am-11:54 pm

2 stops17h 08m

$223

Myrtle BeachMiami

MYR - MIA

MYRMIA

Myrtle Beach Intl

Fri 11/14

2:46 pm-9:58 am

2 stops19h 12m

Miami

Wed 11/19

12:17 pm-8:03 pm

3 stops31h 46m

$233

Myrtle BeachMiami

MYR - MIA

MYRMIA

Myrtle Beach Intl

Wed 11/19

12:30 pm-9:30 pm

1 stop9h 00m

Miami

Mon 11/24

6:46 am-11:54 pm

2 stops17h 08m

$242

Myrtle BeachMiami

MYR - MIA

MYRMIA

Myrtle Beach Intl

Fri 11/14

2:46 pm-6:44 pm

3 stops27h 58m

Miami

Sun 11/16

9:59 pm-10:26 pm

3 stops24h 27m

$255

Myrtle BeachMiami

MYR - MIA

MYRMIA

Myrtle Beach Intl

Sat 1/24

6:18 pm-9:10 am

1 stop14h 52m

Miami

Sun 2/1

1:56 pm-10:41 am

3 stops20h 45m

$264

Myrtle BeachMiami

MYR - MIA

MYRMIA

Myrtle Beach Intl

Fri 11/14

10:51 am-10:52 pm

1 stop12h 01m

Miami

Fri 11/21

8:20 pm-12:21 pm

1 stop16h 01m

$285

Myrtle BeachMiami

MYR - MIA

MYRMIA

Myrtle Beach Intl

Fri 11/14

2:46 pm-9:58 am

2 stops19h 12m

$74

Flights are sorted by cheapest round-trip flights first.

Deals found on 10/29

Showing 1-10 of 19 results
1
2

Best time to book a flight from Myrtle Beach to Key Largo

Have a flexible travel schedule? Discover the best time to fly to Key Largo from Myrtle Beach with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Myrtle Beach to Key Largo

How far ahead should I book a flight from Myrtle Beach to Key Largo?

Use this chart to determine the optimal time to book a round-trip flight from Myrtle Beach to Key Largo. Price data was last updated on October 24, 2025.

To ensure you get the cheapest price possible for a flight from Myrtle Beach to Key Largo, you should look to book at least 18 days in advance of your intended travel date. The price of your flight may increase if you delay and leave booking until a week or so before departure.

What is the cheapest month to book a flight from Myrtle Beach to Key Largo?

Currently, March is the cheapest month in which you can book a flight from Myrtle Beach to Key Largo (average of $33). Flying from Myrtle Beach to Key Largo in June is currently the most expensive (average of $76). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

What is the cheapest time of day to fly from MYR to KE9?

Find hourly flight availability from Myrtle Beach to Key Largo. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated October 30, 2025.

Unlike in the evening, when flights are generally more expensive, you can save up to 17% on flights from Myrtle Beach to Key Largo by exploring options for tickets at noon.

What is the cheapest day to fly from Myrtle Beach to Key Largo?

Use this chart to determine the cheapest time to fly round-trip from Myrtle Beach to Key Largo. Price data was last updated on December 16, 2024.

Travelers seeking maximum savings on their Myrtle Beach to Key Largo flight should consider departing on Tuesday at noon when fares are most often at their lowest. Wednesday mornings flights should be avoided if possible as fares are typically the most expensive at this time.

How much does it cost to fly round-trip from Myrtle Beach to Key Largo?

Reviews of airlines servicing Key Largo

Get insights into the airlines that provide service to Key Largo. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Key Largo. Reviews last updated October 30, 2025.
Get a feel of what it's like to fly with Delta, American Airlines, and Spirit Airlines from Myrtle Beach to Key Largo by reading reviews from past customers. Users have also rated airlines in terms of entertainment options, comfort, food, crew/service, and boarding process.
Delta
7.9
Good
7,998 reviews

Overall

7.9

Entertainment

7.9

Boarding

8.2

Food

7.3

Crew

8.5

Comfort

7.9

Reviews

1 / 20
8.0
Excellent

Matthew,Oct 2025

GSP - ATL

This is always a full flight since it is the connecting route to primary destinations through Atlanta. That said, the crew handles the full load well. Not much more to say, it is a short flight with no in-flight services due to the length.
Delta
7.9
Good
7,998 reviews
Delta
7.9
Good
7,998 reviews

Overall

7.9

Entertainment

7.9

Boarding

8.2

Food

7.3

Crew

8.5

Comfort

7.9

Reviews

1 / 20
8.0
Excellent

Matthew,Oct 2025

GSP - ATL

This is always a full flight since it is the connecting route to primary destinations through Atlanta. That said, the crew handles the full load well. Not much more to say, it is a short flight with no in-flight services due to the length.
American Airlines
7.2
Good
11,034 reviews
Delta
7.9
Good
7,998 reviews

Overall

7.9

Entertainment

7.9

Boarding

8.2

Food

7.3

Crew

8.5

Comfort

7.9

Reviews

1 / 20
8.0
Excellent

Matthew,Oct 2025

GSP - ATL

This is always a full flight since it is the connecting route to primary destinations through Atlanta. That said, the crew handles the full load well. Not much more to say, it is a short flight with no in-flight services due to the length.
Spirit Airlines
6.3
Okay
8,115 reviews
Delta
7.9
Good
7,998 reviews

Overall

7.9

Entertainment

7.9

Boarding

8.2

Food

7.3

Crew

8.5

Comfort

7.9

Reviews

1 / 20
8.0
Excellent

Matthew,Oct 2025

GSP - ATL

This is always a full flight since it is the connecting route to primary destinations through Atlanta. That said, the crew handles the full load well. Not much more to say, it is a short flight with no in-flight services due to the length.

Related info for your journey

Find useful and relevant information for your journey from Myrtle Beach to Key Largo. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • What airport do you fly from for flights from Myrtle Beach to Key Largo?

    If you book a flight to Key Largo from Myrtle Beach, you will be flying from Myrtle Beach Intl, which is the city’s only airport. Myrtle Beach Intl (MYR) is located 2.1 mi from the center of Myrtle Beach. There are 0 flights from Myrtle Beach Intl to Key Largo per day from 3 different airlines.

  • How long is the flight from Myrtle Beach to Key Largo?

    Spirit Airlines can get you from Myrtle Beach to Key Largo in just under 5h 58m. Your travel time can differ by up to . The distance from Myrtle Beach to Key Largo is about 551 mi.

  • Can I find deals for flights from Myrtle Beach to Key Largo that include hotel bookings?

    Yes. In addition to deals on Myrtle Beach to Key Largo flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Myrtle Beach to Key Largo?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Myrtle Beach to Key Largo.

  • Can I find deals for business class flights from Myrtle Beach to Key Largo?

    Yes. Cheapflights offers flight deals from Myrtle Beach to Key Largo by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Myrtle Beach to Key Largo?

    Currently, March is the cheapest month in which you can book a flight from Myrtle Beach to Key Largo (average of $33). Flying from Myrtle Beach to Key Largo in June is currently the most expensive (average of $76). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

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Top 3 airlines flying from Myrtle Beach to Key Largo

Discover the top 3 airlines that operate flights from Myrtle Beach to Key Largo. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated October 30, 2025.
AirlineCheapestAverageFlexibilityOn-time
Spirit AirlinesCheapest$85Average$174FlexibilityNo cancel feeOn-time65%
DeltaCheapest$223Average$418FlexibilityNo cancel feeOn-timeN/A
American AirlinesCheapest$256Average$423FlexibilityNo cancel feeOn-time71%

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