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Key Largo

$75+ Cheap flights from Myrtle Beach (MYR) to Key Largo, FL

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 3/3. Fares are subject to change and may not be available on all flights or dates of travel.
MYR — MIA
Feb 11 — Feb 181
Wed 2/11
Wed 2/18
1 adult, Economy
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Cheap flight deals from Myrtle Beach to Key Largo

Keep the following information in mind while searching for Myrtle Beach to Key Largo flight deals. Data was last updated January 12, 2026.

Most accurate provider

eDreams
3 stars

Most trusted provider

eDreams
3 stars

Round-trip from

$146
(Kiwi.com)

One-way from

$75
(CheapOair)

Popular in

April

Cheapest in

October

Average price

$337
Provider with most accurate pricing for Myrtle Beach Intl-Miami flight deals.
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Provider most trusted by Cheapflights users for Myrtle Beach Intl-Miami flights.
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From Myrtle Beach Intl to Key Largo
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One-way flight from Myrtle Beach Intl to Key Largo
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Highest demand for flights based on searches. 2% potential increase in price ($8 potential increase over avg. RT price).
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Cheapest flight prices on average. 1% potential price decrease ($5 potential savings vs. average RT price).
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Average for round-trip flights in January 2026
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Find flight deals from Myrtle Beach to Key Largo

Cheapest flights from Myrtle Beach to Key Largo
Explore the most affordable flight options available from Myrtle Beach to Key Largo. Find the lowest fares from popular airlines and budget airlines, with prices last updated on January 12, 2026.

This Kiwi.com deal was found by Cheapflights users on 1/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 2/2811:57 am
MYR
-
MIA
1 stop13h 17m
Multiple Airlines
Wed 3/46:00 am
MIA
-
MYR
1 stop8h 55m
Multiple Airlines
Deal found 1/12$146
This Kiwi.com deal was found by Cheapflights users on 1/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 2/2410:09 am
MYR
-
MIA
1 stop15h 05m
Multiple Airlines
Fri 2/276:00 am
MIA
-
MYR
1 stop29h 02m
Multiple Airlines
Deal found 1/12$153
This Expedia deal was found by Cheapflights users on 1/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Expedia is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 2/1110:00 am
MYR
-
MIA
1 stop10h 13m
Spirit Airlines
Tue 2/171:24 pm
MIA
-
MYR
1 stop10h 33m
Spirit Airlines
Deal found 1/12$169
This CheapOair deal was found by Cheapflights users on 1/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure CheapOair is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 2/710:00 am
MYR
-
MIA
1 stop10h 13m
Spirit Airlines
Sat 2/141:24 pm
MIA
-
MYR
1 stop10h 33m
Spirit Airlines
Deal found 1/10$170
This Kiwi.com deal was found by Cheapflights users on 1/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 2/2510:09 am
MYR
-
MIA
1 stop10h 04m
Spirit Airlines
Fri 2/2712:52 pm
MIA
-
MYR
1 stop22h 10m
Spirit Airlines
Deal found 1/12$171
This Cheapflightsfares deal was found by Cheapflights users on 1/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Cheapflightsfares is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 2/210:00 am
MYR
-
MIA
1 stop10h 13m
Spirit Airlines
Thu 2/122:52 pm
MIA
-
MYR
1 stop9h 05m
Spirit Airlines
Deal found 1/10$174
This Delta deal was found by Cheapflights users on 1/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 2/214:00 pm
MYR
-
MIA
1 stop6h 47m
Delta
Tue 2/248:15 am
MIA
-
MYR
1 stop6h 47m
Delta
Deal found 1/11$177
This Kiwi.com deal was found by Cheapflights users on 1/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 2/710:00 am
MYR
-
MIA
1 stop13h 16m
Multiple Airlines
Mon 2/911:47 am
MIA
-
MYR
1 stop26h 55m
Multiple Airlines
Deal found 1/11$178
This Kiwi.com deal was found by Cheapflights users on 1/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 1/2610:00 am
MYR
-
MIA
1 stop10h 13m
Spirit Airlines
Fri 1/3011:38 am
MIA
-
MYR
1 stop27h 04m
Spirit Airlines
Deal found 1/10$184
This Mytrip deal was found by Cheapflights users on 1/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Mytrip is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 2/2410:09 am
MYR
-
MIA
1 stop10h 04m
Spirit Airlines
Fri 2/273:50 pm
MIA
-
MYR
2 stops19h 12m
Spirit Airlines
Deal found 1/12$186
This CheapOair deal was found by Cheapflights users on 1/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure CheapOair is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 2/910:00 am
MYR
-
MIA
1 stop10h 13m
Spirit Airlines
Sat 2/141:24 pm
MIA
-
MYR
1 stop10h 33m
Spirit Airlines
Deal found 1/11$187

Cheapflights Fare Finder

 
Customize your flight search to find flights from Myrtle Beach to Key Largo that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated January 12, 2026.
Use the filters below to find and compare flights from Myrtle Beach to Key Largo that are best for you.

Fly from

Myrtle Beach

Fly to

Key Largo

Route

Depart

Return

Price

Myrtle BeachMiami

MYR - MIA

MYRMIA

Myrtle Beach Intl

Sat 2/28

11:57 am-1:14 am

1 stop13h 17m

Miami

Wed 3/4

6:00 am-2:55 pm

1 stop8h 55m

$146

Myrtle BeachMiami

MYR - MIA

MYRMIA

Myrtle Beach Intl

Tue 2/17

10:31 am-3:41 pm

1 stop5h 10m

Miami

Wed 2/18

4:46 pm-11:57 pm

1 stop7h 11m

$177

Myrtle BeachMiami

MYR - MIA

MYRMIA

Myrtle Beach Intl

Tue 2/10

10:00 am-8:13 pm

1 stop10h 13m

Miami

Tue 2/17

2:52 pm-11:57 pm

1 stop9h 05m

$189

Myrtle BeachMiami

MYR - MIA

MYRMIA

Myrtle Beach Intl

Mon 1/26

10:00 am-8:13 pm

1 stop10h 13m

Miami

Fri 1/30

12:56 pm-9:04 pm

1 stop8h 08m

$205

Myrtle BeachMiami

MYR - MIA

MYRMIA

Myrtle Beach Intl

Mon 1/26

10:00 am-8:13 pm

1 stop10h 13m

Miami

Fri 1/30

4:03 pm-7:20 pm

2 stops27h 17m

$219

Myrtle BeachMiami

MYR - MIA

MYRMIA

Myrtle Beach Intl

Sat 2/21

4:00 pm-10:47 pm

1 stop6h 47m

Miami

Mon 2/23

7:26 pm-11:57 pm

1 stop4h 31m

$228

Myrtle BeachMiami

MYR - MIA

MYRMIA

Myrtle Beach Intl

Wed 2/18

4:00 pm-8:44 pm

1 stop4h 44m

Miami

Mon 2/23

7:26 pm-11:57 pm

1 stop4h 31m

$228

Myrtle BeachMiami

MYR - MIA

MYRMIA

Myrtle Beach Intl

Tue 2/10

10:00 am-8:13 pm

1 stop10h 13m

Miami

Sun 2/15

2:52 pm-11:57 pm

1 stop9h 05m

$242

Myrtle BeachMiami

MYR - MIA

MYRMIA

Myrtle Beach Intl

Sun 2/8

10:00 am-8:13 pm

1 stop10h 13m

Miami

Sun 2/15

2:52 pm-11:57 pm

1 stop9h 05m

$259

Myrtle BeachMiami

MYR - MIA

MYRMIA

Myrtle Beach Intl

Sat 1/31

10:00 am-8:13 pm

1 stop10h 13m

Miami

Sun 2/1

8:51 pm-7:20 pm

2 stops22h 29m

$275

Flights are sorted by cheapest round-trip flights first.

Deals found on 1/11

Showing 1-10 of 21 results
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Best time to book a flight from Myrtle Beach to Key Largo

Have a flexible travel schedule? Discover the best time to fly to Key Largo from Myrtle Beach with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Myrtle Beach to Key Largo

How far ahead should I book a flight from Myrtle Beach to Key Largo?

Use this chart to determine the optimal time to book a round-trip flight from Myrtle Beach to Key Largo. Price data was last updated on January 9, 2026.

To ensure you get the cheapest price possible for a flight from Myrtle Beach to Key Largo, you should look to book at least 18 days in advance of your intended travel date. The price of your flight may increase if you delay and leave booking until a week or so before departure.

What is the cheapest month to book a flight from Myrtle Beach to Key Largo?

Currently, March is the cheapest month in which you can book a flight from Myrtle Beach to Key Largo (average of $33). Flying from Myrtle Beach to Key Largo in June is currently the most expensive (average of $76). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

What is the cheapest time of day to fly from MYR to KE9?

Find hourly flight availability from Myrtle Beach to Key Largo. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated January 12, 2026.

Unlike in the morning, when flights are generally more expensive, you can save up to 30% on flights from Myrtle Beach to Key Largo by exploring options for tickets in the afternoon.

What is the cheapest day to fly from Myrtle Beach to Key Largo?

Use this chart to determine the cheapest time to fly round-trip from Myrtle Beach to Key Largo. Price data was last updated on January 10, 2026.

Travelers seeking maximum savings on their Myrtle Beach to Key Largo flight should consider departing on Tuesday at noon when fares are most often at their lowest. Monday at noon flights should be avoided if possible as fares are typically the most expensive at this time.

Reviews of airlines servicing Key Largo

Get insights into the airlines that provide service to Key Largo. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Key Largo. Reviews last updated January 12, 2026.
Get a feel of what it's like to fly with Delta, American Airlines, and Spirit Airlines from Myrtle Beach to Key Largo by reading reviews from past customers. Users have also rated airlines in terms of entertainment options, comfort, food, crew/service, and boarding process.
Delta
7.9
Good
8,033 reviews

Boarding

8.1

Comfort

7.9

Entertainment

7.8

Food

7.2

Overall

7.9

Crew

8.5

Reviews

1 / 20
8.0
Excellent

Matthew,Oct 2025

GSP - ATL

This is always a full flight since it is the connecting route to primary destinations through Atlanta. That said, the crew handles the full load well. Not much more to say, it is a short flight with no in-flight services due to the length.
Delta
7.9
Good
8,033 reviews
Delta
7.9
Good
8,033 reviews

Boarding

8.1

Comfort

7.9

Entertainment

7.8

Food

7.2

Overall

7.9

Crew

8.5

Reviews

1 / 20
8.0
Excellent

Matthew,Oct 2025

GSP - ATL

This is always a full flight since it is the connecting route to primary destinations through Atlanta. That said, the crew handles the full load well. Not much more to say, it is a short flight with no in-flight services due to the length.
American Airlines
7.2
Good
11,111 reviews
Delta
7.9
Good
8,033 reviews

Boarding

8.1

Comfort

7.9

Entertainment

7.8

Food

7.2

Overall

7.9

Crew

8.5

Reviews

1 / 20
8.0
Excellent

Matthew,Oct 2025

GSP - ATL

This is always a full flight since it is the connecting route to primary destinations through Atlanta. That said, the crew handles the full load well. Not much more to say, it is a short flight with no in-flight services due to the length.
Spirit Airlines
6.3
Okay
8,296 reviews
Delta
7.9
Good
8,033 reviews

Boarding

8.1

Comfort

7.9

Entertainment

7.8

Food

7.2

Overall

7.9

Crew

8.5

Reviews

1 / 20
8.0
Excellent

Matthew,Oct 2025

GSP - ATL

This is always a full flight since it is the connecting route to primary destinations through Atlanta. That said, the crew handles the full load well. Not much more to say, it is a short flight with no in-flight services due to the length.

Related info for your journey

Find useful and relevant information for your journey from Myrtle Beach to Key Largo. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • What airport do you fly from for flights from Myrtle Beach to Key Largo?

    If you book a flight to Key Largo from Myrtle Beach, you will be flying from Myrtle Beach Intl, which is the city’s only airport. Myrtle Beach Intl (MYR) is located 2.1 mi from the center of Myrtle Beach. There are 0 flights from Myrtle Beach Intl to Key Largo per day from 4 different airlines.

  • How long is the flight from Myrtle Beach to Key Largo?

    Delta and Spirit Airlines can get you from Myrtle Beach to Key Largo in just under 5h 10m. Your travel time can differ by up to 5h 03m. The distance from Myrtle Beach to Key Largo is about 551 mi. When browsing for deals, the options you’ll see will be for both nonstop flights and flights with stops.

  • What are the cheapest airlines to fly from Myrtle Beach to Key Largo one-way?

    The cheapest airlines for a one-way flight from Myrtle Beach to Key Largo are Spirit Airlines ($45), American Airlines ($99), and Delta ($104).

  • Can I find deals for flights from Myrtle Beach to Key Largo that include hotel bookings?

    Yes. In addition to deals on Myrtle Beach to Key Largo flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Myrtle Beach to Key Largo?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Myrtle Beach to Key Largo.

  • Can I find deals for business class flights from Myrtle Beach to Key Largo?

    Yes. Cheapflights offers flight deals from Myrtle Beach to Key Largo by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Myrtle Beach to Key Largo?

    Currently, March is the cheapest month in which you can book a flight from Myrtle Beach to Key Largo (average of $33). Flying from Myrtle Beach to Key Largo in June is currently the most expensive (average of $76). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

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Top 4 airlines flying from Myrtle Beach to Key Largo

Discover the top 4 airlines that operate flights from Myrtle Beach to Key Largo. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated January 12, 2026.
AirlineCheapestAverageFlexibilityOn-time
Spirit AirlinesCheapest$86Average$168FlexibilityNo cancel feeOn-time65%
Breeze AirwaysCheapest$129Average$168FlexibilityNo cancel feeOn-timeN/A
DeltaCheapest$176Average$422FlexibilityNo cancel feeOn-timeN/A
American AirlinesCheapest$252Average$404FlexibilityNo cancel feeOn-time71%

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