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Key Largo

$82+ Cheap flights from Myrtle Beach (MYR) to Key Largo, FL

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 3/4. Fares are subject to change and may not be available on all flights or dates of travel.
MYR — MIA
Mar 29 — Apr 51
Sun 3/29
Sun 4/5
1 adult, Economy
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Cheap flight deals from Myrtle Beach to Key Largo

Cheapest flights from Myrtle Beach to Key Largo
Explore the most affordable flight options available from Myrtle Beach to Key Largo. Find the lowest fares from popular airlines and budget airlines, with prices last updated on February 27, 2026.

This Priceline deal was found by Cheapflights users on 2/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Priceline is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 4/179:42 am
MYR
-
MIA
1 stop9h 40m
Multiple Airlines
Fri 4/2411:31 am
MIA
-
MYR
1 stop7h 41m
Multiple Airlines
Deal found 2/23$168
This CheapOair deal was found by Cheapflights users on 2/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure CheapOair is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 4/165:29 pm
MYR
-
MIA
1 stop20h 38m
Frontier
Sun 4/197:00 am
MIA
-
MYR
1 stop9h 44m
Frontier
Deal found 2/25$171
This Cheapflightsfares deal was found by Cheapflights users on 2/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Cheapflightsfares is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 4/179:42 am
MYR
-
MIA
1 stop9h 40m
Spirit Airlines
Sat 4/2510:55 am
MIA
-
MYR
1 stop6h 53m
Spirit Airlines
Deal found 2/25$174
This CheapOair deal was found by Cheapflights users on 2/24. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure CheapOair is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 4/249:42 am
MYR
-
MIA
1 stop9h 40m
Spirit Airlines
Wed 4/2910:55 am
MIA
-
MYR
1 stop6h 53m
Spirit Airlines
Deal found 2/24$175
This CheapOair deal was found by Cheapflights users on 2/24. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure CheapOair is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 4/239:42 am
MYR
-
MIA
1 stop9h 40m
Multiple Airlines
Sun 4/266:15 am
MIA
-
MYR
1 stop10h 29m
Multiple Airlines
Deal found 2/24$178
This Expedia deal was found by Cheapflights users on 2/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Expedia is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 4/165:29 pm
MYR
-
MIA
1 stop20h 38m
Frontier
Mon 4/207:00 am
MIA
-
MYR
1 stop9h 44m
Frontier
Deal found 2/26$181
This CheapOair deal was found by Cheapflights users on 2/24. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure CheapOair is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 4/159:42 am
MYR
-
MIA
1 stop9h 40m
Spirit Airlines
Sat 4/1810:55 am
MIA
-
MYR
1 stop6h 53m
Spirit Airlines
Deal found 2/24$194
This CheapOair deal was found by Cheapflights users on 2/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure CheapOair is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 4/259:42 am
MYR
-
MIA
1 stop9h 40m
Multiple Airlines
Fri 5/17:00 am
MIA
-
MYR
1 stop9h 44m
Multiple Airlines
Deal found 2/23$199
This Expedia deal was found by Cheapflights users on 2/24. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Expedia is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 5/314:11 pm
MYR
-
MIA
1 stop27h 07m
Frontier
Sun 6/78:18 pm
MIA
-
MYR
1 stop19h 03m
Frontier
Deal found 2/24$202
This CheapOair deal was found by Cheapflights users on 2/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure CheapOair is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 4/179:42 am
MYR
-
MIA
1 stop9h 40m
Spirit Airlines
Mon 4/2010:55 am
MIA
-
MYR
1 stop6h 53m
Spirit Airlines
Deal found 2/23$213
This Frontier deal was found by Cheapflights users on 2/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Frontier is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 4/58:54 am
MYR
-
MIA
1 stop12h 14m
Frontier
Thu 4/99:07 am
MIA
-
MYR
1 stop11h 52m
Frontier
Deal found 2/26$215
This Cheapflightsfares deal was found by Cheapflights users on 2/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Cheapflightsfares is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 4/259:42 am
MYR
-
MIA
1 stop9h 40m
Spirit Airlines
Fri 5/110:55 am
MIA
-
MYR
1 stop6h 53m
Spirit Airlines
Deal found 2/23$216

Find flight deals from Myrtle Beach to Key Largo

Keep the following information in mind while searching for Myrtle Beach to Key Largo flight deals. Data was last updated February 27, 2026.

Most accurate provider

FlightHub
3 stars

Most trusted provider

FlightHub
3 stars

Round-trip from

$168
(Priceline)

One-way from

$82
(Cheapflightsfares)

Popular in

February

Cheapest in

October

Average price

$418
Provider with most accurate pricing for Myrtle Beach Intl-Miami flight deals.
Search Deals
Provider most trusted by Cheapflights users for Myrtle Beach Intl-Miami flights.
Search Deals
From Myrtle Beach Intl to Key Largo
Search Deals
One-way flight from Myrtle Beach Intl to Key Largo
Search Deals
Highest demand for flights based on searches. 7% potential increase in price ($30 potential increase over avg. RT price).
Search Deals
Cheapest flight prices on average. 1% potential price decrease ($6 potential savings vs. average RT price).
Search Deals
Average for round-trip flights in February 2026
Search Deals

Cheapflights Fare Finder

 
Customize your flight search to find flights from Myrtle Beach to Key Largo that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated February 27, 2026.
Use the filters below to find and compare flights from Myrtle Beach to Key Largo that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

Myrtle BeachMiami

MYR - MIA

MYRMIA

Myrtle Beach Intl

Thu 6/11

12:50 pm-11:49 am

2 stops22h 59m

Miami

Mon 6/15

7:00 am-9:41 am

2 stops26h 41m

$302

Myrtle BeachMiami

MYR - MIA

MYRMIA

Myrtle Beach Intl

Sun 5/10

4:45 pm-11:05 pm

1 stop6h 20m

Miami

Tue 5/12

12:10 pm-8:30 pm

2 stops8h 20m

$345

Myrtle BeachMiami

MYR - MIA

MYRMIA

Myrtle Beach Intl

Sun 7/12

7:50 pm-12:56 am

1 stop5h 06m

Miami

Fri 7/17

6:00 am-10:09 am

1 stop4h 09m

$367

Myrtle BeachMiami

MYR - MIA

MYRMIA

Myrtle Beach Intl

Tue 7/28

7:55 am-3:45 pm

1 stop7h 50m

Miami

Fri 7/31

4:00 pm-9:20 pm

1 stop5h 20m

$377

Myrtle BeachMiami

MYR - MIA

MYRMIA

Myrtle Beach Intl

Fri 3/20

6:28 pm-8:07 pm

3 stops25h 39m

Miami

Thu 3/26

9:45 pm-5:33 pm

3 stops19h 48m

$389

Myrtle BeachMiami

MYR - MIA

MYRMIA

Myrtle Beach Intl

Thu 4/16

10:55 am-10:00 pm

2 stops11h 05m

Miami

Sun 4/19

6:10 am-3:05 pm

2 stops8h 55m

$403

Myrtle BeachMiami

MYR - MIA

MYRMIA

Myrtle Beach Intl

Sat 4/25

10:35 am-7:40 pm

2 stops9h 05m

Miami

Fri 5/1

6:20 am-3:10 pm

2 stops8h 50m

$417

Myrtle BeachMiami

MYR - MIA

MYRMIA

Myrtle Beach Intl

Thu 6/18

11:55 am-11:15 pm

1 stop11h 20m

Miami

Mon 6/22

5:40 am-6:35 pm

2 stops12h 55m

$426

Myrtle BeachMiami

MYR - MIA

MYRMIA

Myrtle Beach Intl

Sun 5/24

2:15 pm-9:25 pm

2 stops7h 10m

Miami

Thu 5/28

6:40 am-6:45 pm

2 stops12h 05m

$427

Myrtle BeachMiami

MYR - MIA

MYRMIA

Myrtle Beach Intl

Thu 6/18

11:55 am-11:15 pm

1 stop11h 20m

Miami

Sun 6/21

6:20 am-5:10 pm

1 stop10h 50m

$438

Flights are sorted by cheapest round-trip flights first.

Deals found on 2/25

Showing 1-10 of 21 resultsSorted by cheapest first
1
2
3

Best time to book a flight from Myrtle Beach to Key Largo

Have a flexible travel schedule? Discover the best time to fly to Key Largo from Myrtle Beach with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Myrtle Beach to Key Largo

How far ahead should I book a flight from Myrtle Beach to Key Largo?

Use this chart to determine the optimal time to book a round-trip flight from Myrtle Beach to Key Largo. Price data was last updated on February 20, 2026.

To ensure you get the cheapest price possible for a flight from Myrtle Beach to Key Largo, you should look to book at least 18 days in advance of your intended travel date. The price of your flight may increase if you delay and leave booking until a week or so before departure.

What is the cheapest month to book a flight from Myrtle Beach to Key Largo?

Currently, March is the cheapest month in which you can book a flight from Myrtle Beach to Key Largo (average of $33). Flying from Myrtle Beach to Key Largo in June is currently the most expensive (average of $75). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

What is the cheapest time of day to fly from MYR to KE9?

Find hourly flight availability from Myrtle Beach to Key Largo. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated February 27, 2026.

Unlike in the morning, when flights are generally more expensive, you can save up to 29% on flights from Myrtle Beach to Key Largo by exploring options for tickets in the afternoon.

What is the cheapest day to fly from Myrtle Beach to Key Largo?

Use this chart to determine the cheapest time to fly round-trip from Myrtle Beach to Key Largo. Price data was last updated on February 21, 2026.

Travelers seeking maximum savings on their Myrtle Beach to Key Largo flight should consider departing on Tuesday at noon when fares are most often at their lowest. Monday at noon flights should be avoided if possible as fares are typically the most expensive at this time.

Reviews of airlines servicing Key Largo

Get insights into the airlines that provide service to Key Largo. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Key Largo. Reviews last updated February 27, 2026.
Get a feel of what it's like to fly with Delta, American Airlines, and Spirit Airlines from Myrtle Beach to Key Largo by reading reviews from past customers. Users have also rated airlines in terms of entertainment options, comfort, food, crew/service, and boarding process.
Delta
7.9
Good
8,241 reviews

Comfort

7.9

Food

7.2

Overall

7.9

Entertainment

7.8

Boarding

8.1

Crew

8.5

Reviews

1 / 20
8.0
Excellent

Matthew,Oct 2025

GSP - ATL

This is always a full flight since it is the connecting route to primary destinations through Atlanta. That said, the crew handles the full load well. Not much more to say, it is a short flight with no in-flight services due to the length.
Delta
7.9
Good
8,241 reviews
Delta
7.9
Good
8,241 reviews

Comfort

7.9

Food

7.2

Overall

7.9

Entertainment

7.8

Boarding

8.1

Crew

8.5

Reviews

1 / 20
8.0
Excellent

Matthew,Oct 2025

GSP - ATL

This is always a full flight since it is the connecting route to primary destinations through Atlanta. That said, the crew handles the full load well. Not much more to say, it is a short flight with no in-flight services due to the length.
American Airlines
7.2
Good
11,360 reviews
Delta
7.9
Good
8,241 reviews

Comfort

7.9

Food

7.2

Overall

7.9

Entertainment

7.8

Boarding

8.1

Crew

8.5

Reviews

1 / 20
8.0
Excellent

Matthew,Oct 2025

GSP - ATL

This is always a full flight since it is the connecting route to primary destinations through Atlanta. That said, the crew handles the full load well. Not much more to say, it is a short flight with no in-flight services due to the length.
Spirit Airlines
6.3
Okay
8,492 reviews
Delta
7.9
Good
8,241 reviews

Comfort

7.9

Food

7.2

Overall

7.9

Entertainment

7.8

Boarding

8.1

Crew

8.5

Reviews

1 / 20
8.0
Excellent

Matthew,Oct 2025

GSP - ATL

This is always a full flight since it is the connecting route to primary destinations through Atlanta. That said, the crew handles the full load well. Not much more to say, it is a short flight with no in-flight services due to the length.

Related info for your journey

Find useful and relevant information for your journey from Myrtle Beach to Key Largo. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • What airport do you fly from for flights from Myrtle Beach to Key Largo?

    If you book a flight to Key Largo from Myrtle Beach, you will be flying from Myrtle Beach Intl, which is the city’s only airport. Myrtle Beach Intl (MYR) is located 2.1 mi from the center of Myrtle Beach. There are 0 flights from Myrtle Beach Intl to Key Largo per day from 4 different airlines.

  • How long is the flight from Myrtle Beach to Key Largo?

    Spirit Airlines, Delta, and Southwest can get you from Myrtle Beach to Key Largo in just under 5h 06m. Your travel time can differ by up to 17h 53m. The distance from Myrtle Beach to Key Largo is about 551 mi. When browsing for deals, the options you’ll see will be for both nonstop flights and flights with stops.

  • What are the cheapest airlines to fly from Myrtle Beach to Key Largo one-way?

    The cheapest airlines for a one-way flight from Myrtle Beach to Key Largo are Spirit Airlines ($45), American Airlines ($99), and Delta ($104).

  • Can I find deals for flights from Myrtle Beach to Key Largo that include hotel bookings?

    Yes. In addition to deals on Myrtle Beach to Key Largo flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Myrtle Beach to Key Largo?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Myrtle Beach to Key Largo.

  • Can I find deals for business class flights from Myrtle Beach to Key Largo?

    Yes. Cheapflights offers flight deals from Myrtle Beach to Key Largo by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Myrtle Beach to Key Largo?

    Currently, March is the cheapest month in which you can book a flight from Myrtle Beach to Key Largo (average of $33). Flying from Myrtle Beach to Key Largo in June is currently the most expensive (average of $75). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

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Top 4 airlines flying from Myrtle Beach to Key Largo

Discover the top 4 airlines that operate flights from Myrtle Beach to Key Largo. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated February 27, 2026.
AirlineCheapestAverageFlexibilityOn-time
Spirit AirlinesCheapest$86Average$181FlexibilityNo cancel feeOn-time65%
DeltaCheapest$100Average$405FlexibilityNo cancel feeOn-timeN/A
Breeze AirwaysCheapest$112Average$168FlexibilityNo cancel feeOn-timeN/A
American AirlinesCheapest$246Average$400FlexibilityNo cancel feeOn-time71%

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