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Key Largo

$87+ Cheap flights from Myrtle Beach (MYR) to Key Largo, FL

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 12/17. Fares are subject to change and may not be available on all flights or dates of travel.
MYR — MIA
oct. 15 — oct. 221
mié. 10/15
mié. 10/22
1 adult, Economy
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Cheapflights Tip: The best prices from Myrtle Beach Intl to Key Largo are usually found in October or August, booked 36 days in advance, depart on a Monday or Wednesday and return on a Monday

Cheap flight deals from Myrtle Beach to Key Largo

Keep the following information in mind while searching for Myrtle Beach to Key Largo flight deals. Data was last updated septiembre 15, 2025.

Round-trip from

$178
(Kiwi.com)

One-way from

$87
(Cheapflightsfares)

Popular in

April

Cheapest in

October

Average price

$338
From Myrtle Beach Intl to Key Largo
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One-way flight from Myrtle Beach Intl to Key Largo
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Highest demand for flights based on searches. 6% potential increase in price ($23 potential increase over avg. RT price).
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Cheapest flight prices on average. 1% potential price decrease ($6 potential savings vs. average RT price).
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Average for round-trip flights in September 2025
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Find flight deals from Myrtle Beach to Key Largo

Cheapest flights from Myrtle Beach to Key Largo
Explore the most affordable flight options available from Myrtle Beach to Key Largo. Find the lowest fares from popular airlines and budget airlines, with prices last updated on septiembre 15, 2025.

This Kiwi.com deal was found by Cheapflights users on 9/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
vie. 10/173:49 pmMYR - MIA
1 stop26h 33mFrontier
jue. 10/231:00 pmMIA - MYR
1 stop25h 54mFrontier
Deal found 9/12$161
This Kiwi.com deal was found by Cheapflights users on 9/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
vie. 10/173:49 pmMYR - MIA
1 stop26h 33mMultiple Airlines
vie. 10/249:24 pmMIA - MYR
2 stops20h 25mMultiple Airlines
Deal found 9/13$201
This Kiwi.com deal was found by Cheapflights users on 9/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
vie. 10/103:49 pmMYR - MIA
1 stop26h 33mMultiple Airlines
sáb. 10/187:42 pmMIA - MYR
1 stop14h 23mMultiple Airlines
Deal found 9/14$203
This Kiwi.com deal was found by Cheapflights users on 9/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
sáb. 10/49:11 amMYR - MIA
1 stop14h 01mMultiple Airlines
dom. 10/56:00 amMIA - MYR
1 stop9h 16mMultiple Airlines
Deal found 9/14$206
This American Airlines deal was found by Cheapflights users on 9/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
jue. 10/235:59 pmMYR - MIA
1 stop6h 30mAmerican Airlines
lun. 10/275:18 amMIA - MYR
1 stop5h 18mAmerican Airlines
Deal found 9/12$209
This Kiwi.com deal was found by Cheapflights users on 9/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
vie. 9/264:04 pmMYR - MIA
1 stop29h 01mMultiple Airlines
lun. 9/298:04 pmMIA - MYR
1 stop17h 46mMultiple Airlines
Deal found 9/13$212
This Kiwi.com deal was found by Cheapflights users on 9/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
jue. 10/234:06 pmMYR - MIA
1 stop27h 23mMultiple Airlines
lun. 10/277:52 pmMIA - MYR
1 stop16h 56mMultiple Airlines
Deal found 9/15$216
This Kiwi.com deal was found by Cheapflights users on 9/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
lun. 9/296:00 amMYR - MIA
1 stop11h 02mSpirit Airlines
jue. 10/26:00 amMIA - MYR
2 stops14h 06mSpirit Airlines
Deal found 9/15$220
This Kiwi.com deal was found by Cheapflights users on 9/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
mié. 10/19:11 amMYR - MIA
1 stop17h 03mMultiple Airlines
dom. 10/56:00 amMIA - MYR
1 stop9h 16mMultiple Airlines
Deal found 9/13$227
This KAYAK deal was found by Cheapflights users on 9/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure KAYAK is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
vie. 10/176:47 amMYR - MIA
1 stop13h 45mSpirit Airlines
dom. 10/199:49 amMIA - MYR
1 stop14h 07mSpirit Airlines
Deal found 9/13$230

Cheapflights Fare Finder

 
Customize your flight search to find flights from Myrtle Beach to Key Largo that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated septiembre 15, 2025.
Use the filters below to find and compare flights from Myrtle Beach to Key Largo that are best for you.

Fly from

Myrtle Beach

Fly to

Key Largo

Route

Depart

Return

Price

Myrtle BeachMiami

MYR - MIA

MYRMIA

Myrtle Beach Intl

vie. 10/17

3:49 pm-6:22 pm

1 stop26h 33m

Miami

jue. 10/23

1:00 pm-2:54 pm

1 stop25h 54m

$161

Myrtle BeachMiami

MYR - MIA

MYRMIA

Myrtle Beach Intl

vie. 10/10

3:49 pm-6:22 pm

1 stop26h 33m

Miami

sáb. 10/18

7:32 pm-11:36 am

2 stops16h 04m

$201

Myrtle BeachMiami

MYR - MIA

MYRMIA

Myrtle Beach Intl

vie. 10/17

3:49 pm-6:22 pm

1 stop26h 33m

Miami

vie. 10/24

9:24 pm-5:49 pm

2 stops20h 25m

$201

Myrtle BeachMiami

MYR - MIA

MYRMIA

Myrtle Beach Intl

sáb. 10/4

9:11 am-11:12 pm

1 stop14h 01m

Miami

dom. 10/5

6:00 am-3:16 pm

1 stop9h 16m

$206

Myrtle BeachMiami

MYR - MIA

MYRMIA

Myrtle Beach Intl

jue. 10/23

5:59 pm-12:29 am

1 stop6h 30m

Miami

lun. 10/27

5:18 am-10:36 am

1 stop5h 18m

$209

Myrtle BeachMiami

MYR - MIA

MYRMIA

Myrtle Beach Intl

vie. 9/26

4:04 pm-9:05 pm

1 stop29h 01m

Miami

lun. 9/29

8:04 pm-1:50 pm

1 stop17h 46m

$212

Myrtle BeachMiami

MYR - MIA

MYRMIA

Myrtle Beach Intl

lun. 9/29

6:00 am-5:02 pm

1 stop11h 02m

Miami

jue. 10/2

6:00 am-8:06 pm

2 stops14h 06m

$220

Myrtle BeachMiami

MYR - MIA

MYRMIA

Myrtle Beach Intl

mié. 10/1

9:11 am-2:14 am

1 stop17h 03m

Miami

dom. 10/5

6:00 am-3:16 pm

1 stop9h 16m

$227

Myrtle BeachMiami

MYR - MIA

MYRMIA

Myrtle Beach Intl

mié. 11/12

9:59 am-9:12 am

1 stop23h 13m

Miami

mié. 12/3

12:23 pm-8:54 pm

1 stop8h 31m

$237

Myrtle BeachMiami

MYR - MIA

MYRMIA

Myrtle Beach Intl

jue. 10/30

4:59 pm-7:59 pm

1 stop27h 00m

Miami

dom. 11/2

5:05 am-4:04 pm

2 stops10h 59m

$239

Flights are sorted by cheapest round-trip flights first.

Deals found on 9/12

Showing 1-10 of 19 results
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Best time to book a flight from Myrtle Beach to Key Largo

Have a flexible travel schedule? Discover the best time to fly to Key Largo from Myrtle Beach with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Myrtle Beach to Key Largo

How far ahead should I book a flight from Myrtle Beach to Key Largo?

Use this chart to determine the optimal time to book a round-trip flight from Myrtle Beach to Key Largo. Price data was last updated on September 12, 2025.

To ensure you get the cheapest price possible for a flight from Myrtle Beach to Key Largo, you should look to book at least 36 days in advance of your intended travel date. The price of your flight may increase if you delay and leave booking until a week or so before departure.

What is the cheapest month to book a flight from Myrtle Beach to Key Largo?

Currently, September is the cheapest month in which you can book a flight from Myrtle Beach to Key Largo (average of $232). Flying from Myrtle Beach to Key Largo in March is currently the most expensive (average of $289). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

What is the cheapest time of day to fly from MYR to KE9?

Find hourly flight availability from Myrtle Beach to Key Largo. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated septiembre 15, 2025.

Regardless of the time of day you decide to fly, the ticket price will remain around the same. Book flights from Myrtle Beach to Key Largo as you normally would.

What is the cheapest day to fly from Myrtle Beach to Key Largo?

Use this chart to determine the cheapest time to fly round-trip from Myrtle Beach to Key Largo. Price data was last updated on December 16, 2024.

Travelers seeking maximum savings on their Myrtle Beach to Key Largo flight should consider departing on Tuesday at noon when fares are most often at their lowest. Tuesday evenings flights should be avoided if possible as fares are typically the most expensive at this time.

Reviews of airlines servicing Key Largo

Get insights into the airlines that provide service to Key Largo. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Key Largo. Reviews last updated septiembre 15, 2025.
Get a feel of what it's like to fly with Delta, American Airlines, and Spirit Airlines from Myrtle Beach to Key Largo by reading reviews from past customers. Users have also rated airlines in terms of entertainment options, comfort, food, crew/service, and boarding process.
Delta
8.0
Very good
7,954 reviews

Entertainment

7.9

Crew

8.5

Comfort

7.9

Overall

8.0

Food

7.3

Boarding

8.2

Reviews

1 / 20
10.0
Excellent

Lucy,Nov 2023

CAE - ATL

On time flights; courteous staff; efficient boarding system! Thank you!
Delta
8.0
Very good
7,954 reviews
Delta
8.0
Very good
7,954 reviews

Entertainment

7.9

Crew

8.5

Comfort

7.9

Overall

8.0

Food

7.3

Boarding

8.2

Reviews

1 / 20
10.0
Excellent

Lucy,Nov 2023

CAE - ATL

On time flights; courteous staff; efficient boarding system! Thank you!
American Airlines
7.2
Good
10,000 reviews
Delta
8.0
Very good
7,954 reviews

Entertainment

7.9

Crew

8.5

Comfort

7.9

Overall

8.0

Food

7.3

Boarding

8.2

Reviews

1 / 20
10.0
Excellent

Lucy,Nov 2023

CAE - ATL

On time flights; courteous staff; efficient boarding system! Thank you!
Spirit Airlines
6.3
Okay
8,015 reviews
Delta
8.0
Very good
7,954 reviews

Entertainment

7.9

Crew

8.5

Comfort

7.9

Overall

8.0

Food

7.3

Boarding

8.2

Reviews

1 / 20
10.0
Excellent

Lucy,Nov 2023

CAE - ATL

On time flights; courteous staff; efficient boarding system! Thank you!

Related info for your journey

Find useful and relevant information for your journey from Myrtle Beach to Key Largo. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • What airport do you fly from for flights from Myrtle Beach to Key Largo?

    If you book a flight to Key Largo from Myrtle Beach, you will be flying from Myrtle Beach Intl, which is the city’s only airport. Myrtle Beach Intl (MYR) is located 2.1 mi from the center of Myrtle Beach. There are 0 flights from Myrtle Beach Intl to Key Largo per day from 3 different airlines.

  • How long is the flight from Myrtle Beach to Key Largo?

    Frontier and American Airlines can get you from Myrtle Beach to Key Largo in just under 6h 30m. Your travel time can differ by up to 20h 03m. The distance from Myrtle Beach to Key Largo is about 551 mi. When browsing for deals, the options you’ll see will be for both nonstop flights and flights with stops.

  • Can I find deals for flights from Myrtle Beach to Key Largo that include hotel bookings?

    Yes. In addition to deals on Myrtle Beach to Key Largo flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Myrtle Beach to Key Largo?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Myrtle Beach to Key Largo.

  • Can I find deals for business class flights from Myrtle Beach to Key Largo?

    Yes. Cheapflights offers flight deals from Myrtle Beach to Key Largo by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Myrtle Beach to Key Largo?

    Currently, September is the cheapest month in which you can book a flight from Myrtle Beach to Key Largo (average of $232). Flying from Myrtle Beach to Key Largo in March is currently the most expensive (average of $289). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

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Top 3 airlines flying from Myrtle Beach to Key Largo

Discover the top 3 airlines that operate flights from Myrtle Beach to Key Largo. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated septiembre 15, 2025.
AirlineCheapestAverageFlexibilityOn-time
Spirit AirlinesCheapest$84Average$170FlexibilityNo cancel feeOn-time65%
DeltaCheapest$223Average$418FlexibilityNo cancel feeOn-timeN/A
American AirlinesCheapest$256Average$427FlexibilityNo cancel feeOn-time71%

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