$116+ Cheap flights from Myrtle Beach (MYR) to Key Largo, FL
This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 9/24. Fares are subject to change and may not be available on all flights or dates of travel.
MYR — MIA
Oct 1 — Oct 81
Round-trip
1 adult, Economy
We work with more than 300 partners to bring you better travel deals
Find cheap flights from Myrtle Beach to Key Largo with Cheapflights
1. Tell us where you want to go
Enter your travel information like dates, passengers, trip type (one-way or round trip), and preferred cabin class then click “Find deals”2. Select your favorite providers
We find the providers serving your travel needs. Choose up to four travel providers to compare side-by-side for flights, hotels, or car rentals.3. Compare prices and book
Review each provider’s pricing and select the best option for you! Book through your favorite provider’s website for a seamless experience.Cheap flight deals from Myrtle Beach to Key Largo
Cheapest
Best
Last-minute
One-way
Cheapest flights from Myrtle Beach to Key LargoExplore the most affordable flight options available from Myrtle Beach to Key Largo. Find the lowest fares from popular airlines and budget airlines, with prices last updated on September 1, 2026.
Explore the most affordable flight options available from Myrtle Beach to Key Largo. Find the lowest fares from popular airlines and budget airlines, with prices last updated on September 1, 2026.
This Frontier deal was found by Cheapflights users on 8/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Frontier is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 9/249:37 am -
1 stop10h 08m
Sat 9/268:50 pm -
1 stop12h 02m
Deal found 8/30![Frontier logo]()
$215
This Frontier deal was found by Cheapflights users on 8/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Frontier is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 9/209:37 am -
1 stop10h 08m
Wed 9/238:50 pm -
1 stop12h 02m
Deal found 8/30![Frontier logo]()
$220
This Frontier deal was found by Cheapflights users on 8/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Frontier is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 9/209:37 am -
1 stop10h 08m
Sat 9/268:50 pm -
1 stop12h 02m
Deal found 8/30![Frontier logo]()
$235
This Kiwi.com deal was found by Cheapflights users on 8/31. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/306:12 pm -
2 stops22h 52m
Sat 11/78:56 pm -
1 stop11h 55m
Deal found 8/31![Multiple Airlines logo]()
$244
This Kiwi.com deal was found by Cheapflights users on 8/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 11/88:05 pm -
2 stops38h 24m
Sat 11/148:56 pm -
1 stop11h 55m
Deal found 8/29![Multiple Airlines logo]()
$264
This Kiwi.com deal was found by Cheapflights users on 8/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 9/2210:50 am -
2 stops23h 40m
Sat 9/268:50 pm -
1 stop12h 02m
Deal found 8/29![Multiple Airlines logo]()
$300
This Kiwi.com deal was found by Cheapflights users on 8/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/19:37 am -
1 stop10h 08m
Mon 10/59:30 pm -
2 stops38h 14m
Deal found 8/29![Multiple Airlines logo]()
$305
This American Airlines deal was found by Cheapflights users on 9/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 9/245:45 pm -
1 stop4h 06m
Wed 9/305:21 pm -
1 stop3h 47m
Deal found 9/1![American Airlines logo]()
$309
This Frontier deal was found by Cheapflights users on 8/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Frontier is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 10/49:37 am -
1 stop10h 08m
Sat 10/108:45 pm -
1 stop12h 02m
Deal found 8/27![Frontier logo]()
$310
This Kiwi.com deal was found by Cheapflights users on 9/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/19:37 am -
1 stop10h 08m
Sun 10/1110:55 pm -
2 stops34h 55m
Deal found 9/1![Multiple Airlines logo]()
$311
This Kiwi.com deal was found by Cheapflights users on 8/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 9/211:48 pm -
2 stops30h 50m
Sat 9/268:50 pm -
1 stop12h 02m
Deal found 8/29![Multiple Airlines logo]()
$316
Best flights from Myrtle Beach to Key LargoDiscover carefully curated flight deals from Myrtle Beach to Key Largo that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated September 1, 2026.
Discover carefully curated flight deals from Myrtle Beach to Key Largo that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated September 1, 2026.
This Delta deal was found by Cheapflights users on 8/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 10/196:58 pm -
1 stop5h 55m
Fri 10/237:10 am -
1 stop6h 21m
Deal found 8/27![Delta logo]()
$317
This Southwest deal was found by Cheapflights users on 8/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 1/288:00 am -
1 stop6h 00m
Mon 2/87:15 am -
2 stops10h 40m
Deal found 8/28![Southwest logo]()
$366
This United Airlines deal was found by Cheapflights users on 8/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 1/103:20 pm -
1 stop6h 45m
Thu 1/2110:20 am -
3 stops24h 17m
Deal found 8/27![United Airlines logo]()
$638
This Southwest deal was found by Cheapflights users on 9/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 2/1010:55 am -
2 stops11h 00m
Mon 2/155:35 am -
2 stops13h 30m
Deal found 9/1![Southwest logo]()
$399
This Southwest deal was found by Cheapflights users on 8/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 2/2710:15 am -
2 stops11h 40m
Sat 3/69:35 am -
1 stop6h 50m
Deal found 8/30![Southwest logo]()
$414
This Delta deal was found by Cheapflights users on 8/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 12/207:03 pm -
1 stop5h 55m
Sat 12/266:00 am -
1 stop4h 01m
Deal found 8/29![Delta logo]()
$487
This United Airlines deal was found by Cheapflights users on 8/31. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 11/1811:27 am -
1 stop8h 14m
Mon 11/239:00 am -
2 stops25h 21m
Deal found 8/31![United Airlines logo]()
$643
This United Airlines deal was found by Cheapflights users on 8/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 10/2410:23 am -
2 stops13h 16m
Sun 11/18:00 am -
1 stop9h 11m
Deal found 8/30![United Airlines logo]()
$695
This United Airlines deal was found by Cheapflights users on 8/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 10/3111:27 am -
1 stop8h 14m
Sun 11/89:00 am -
2 stops25h 21m
Deal found 8/29![United Airlines logo]()
$749
This Southwest deal was found by Cheapflights users on 8/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/11:25 pm -
2 stops9h 40m
Sun 10/46:05 am -
2 stops9h 20m
Deal found 8/28![Southwest logo]()
$758
Last-minute flights from Myrtle Beach to Key LargoDiscover last-minute flight deals from Myrtle Beach to Key Largo. Data last updated September 1, 2026 and is based on user searches.
Discover last-minute flight deals from Myrtle Beach to Key Largo. Data last updated September 1, 2026 and is based on user searches.
This Frontier deal was found by Cheapflights users on 8/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Frontier is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 9/209:37 am -
1 stop10h 08m
Wed 9/238:50 pm -
1 stop12h 02m
Deal found 8/30![Frontier logo]()
$220
This Frontier deal was found by Cheapflights users on 8/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Frontier is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 9/209:37 am -
1 stop10h 08m
Sat 9/268:50 pm -
1 stop12h 02m
Deal found 8/30![Frontier logo]()
$235
This Kiwi.com deal was found by Cheapflights users on 8/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 9/211:48 pm -
2 stops30h 50m
Sat 9/268:50 pm -
1 stop12h 02m
Deal found 8/29![Multiple Airlines logo]()
$316
This Kiwi.com deal was found by Cheapflights users on 8/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 9/2210:50 am -
2 stops23h 40m
Sat 9/268:50 pm -
1 stop12h 02m
Deal found 8/29![Multiple Airlines logo]()
$300
This Frontier deal was found by Cheapflights users on 8/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Frontier is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 9/249:37 am -
1 stop10h 08m
Sat 9/268:50 pm -
1 stop12h 02m
Deal found 8/30![Frontier logo]()
$215
This American Airlines deal was found by Cheapflights users on 9/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 9/245:45 pm -
1 stop4h 06m
Wed 9/305:21 pm -
1 stop3h 47m
Deal found 9/1![American Airlines logo]()
$309
This Kiwi.com deal was found by Cheapflights users on 8/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/19:37 am -
1 stop10h 08m
Mon 10/59:30 pm -
2 stops38h 14m
Deal found 8/29![Multiple Airlines logo]()
$305
This Kiwi.com deal was found by Cheapflights users on 9/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/19:37 am -
1 stop10h 08m
Sun 10/1110:55 pm -
2 stops34h 55m
Deal found 9/1![Multiple Airlines logo]()
$311
This Frontier deal was found by Cheapflights users on 8/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Frontier is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 10/49:37 am -
1 stop10h 08m
Sat 10/108:45 pm -
1 stop12h 02m
Deal found 8/27![Frontier logo]()
$310
This Delta deal was found by Cheapflights users on 8/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 10/196:58 pm -
1 stop5h 55m
Fri 10/237:10 am -
1 stop6h 21m
Deal found 8/27![Delta logo]()
$317
This Kiwi.com deal was found by Cheapflights users on 8/31. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/306:12 pm -
2 stops22h 52m
Sat 11/78:56 pm -
1 stop11h 55m
Deal found 8/31![Multiple Airlines logo]()
$244
One-way flights from Myrtle Beach to Key LargoSearch for one-way flight options from Myrtle Beach to Key Largo. Find affordable one-way fares based on user searches. Data last updated September 1, 2026.
Search for one-way flight options from Myrtle Beach to Key Largo. Find affordable one-way fares based on user searches. Data last updated September 1, 2026.
This Priceline deal was found by Cheapflights users on 8/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Priceline is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 9/249:37 am -
1 stop10h 08m
Deal found 8/29![Frontier logo]()
$116
This Priceline deal was found by Cheapflights users on 8/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Priceline is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 9/209:37 am -
1 stop10h 08m
Deal found 8/29![Frontier logo]()
$136
This Priceline deal was found by Cheapflights users on 8/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Priceline is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 9/109:37 am -
1 stop10h 08m
Deal found 8/27![Frontier logo]()
$156
This Delta deal was found by Cheapflights users on 8/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/26:56 pm -
1 stop6h 01m
Deal found 8/27![Delta logo]()
$163
This Kiwi.com deal was found by Cheapflights users on 8/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 9/2411:59 am -
3 stops32h 34m
Deal found 8/29![Multiple Airlines logo]()
$177
This Kiwi.com deal was found by Cheapflights users on 8/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 9/239:15 am -
3 stops25h 15m
Deal found 8/29![Multiple Airlines logo]()
$179
This Kiwi.com deal was found by Cheapflights users on 8/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 9/112:41 pm -
2 stops29h 57m
Deal found 8/29![Multiple Airlines logo]()
$183
This Kiwi.com deal was found by Cheapflights users on 8/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 9/265:58 pm -
2 stops21h 26m
Deal found 8/29![Multiple Airlines logo]()
$187
This Kiwi.com deal was found by Cheapflights users on 8/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 9/199:15 am -
3 stops25h 15m
Deal found 8/29![Multiple Airlines logo]()
$192
This Kiwi.com deal was found by Cheapflights users on 8/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 9/202:46 pm -
2 stops29h 47m
Deal found 8/29![Multiple Airlines logo]()
$193
Find flight deals from Myrtle Beach to Key Largo
Keep the following information in mind while searching for Myrtle Beach to Key Largo flight deals. Data was last updated September 1, 2026.
Most accurate provider | FlightHub 3 stars |
|---|---|
Most trusted provider | FlightHub 3 stars |
Round-trip from | $215 (Frontier) |
One-way from | $116 (Priceline) |
Popular in | July |
Cheapest in | August |
Average price | $386 |
Cheapflights Fare Finder
Customize your flight search to find flights from Myrtle Beach to Key Largo that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 7,457,451 searches. Data last updated September 1, 2026.
Use the filters below to find and compare flights from Myrtle Beach to Key Largo that are best for you.
Fly from
Fly to
Route
Depart
Return
Cheapest round-trip
Myrtle BeachMiami
MYR Myrtle Beach Intl - MIA Miami
MYRMIA
Myrtle Beach Intl
Mon 10/19
6:58 pm-12:53 am
1 stop5h 55m
Miami
Fri 10/23
7:10 am-1:31 pm
1 stop6h 21m
$317
Myrtle BeachMiami
MYR Myrtle Beach Intl - MIA Miami
MYRMIA
Myrtle Beach Intl
Thu 1/28
8:00 am-2:00 pm
1 stop6h 00m
Miami
Mon 2/8
7:15 am-5:55 pm
2 stops10h 40m
$366
Myrtle BeachMiami
MYR Myrtle Beach Intl - MIA Miami
MYRMIA
Myrtle Beach Intl
Wed 2/10
10:55 am-9:55 pm
2 stops11h 00m
Miami
Mon 2/15
5:35 am-7:05 pm
2 stops13h 30m
$399
Myrtle BeachMiami
MYR Myrtle Beach Intl - MIA Miami
MYRMIA
Myrtle Beach Intl
Sat 2/27
10:15 am-9:55 pm
2 stops11h 40m
Miami
Sat 3/6
9:35 am-4:25 pm
1 stop6h 50m
$414
Quickest round-trip
Myrtle BeachMiami
MYR Myrtle Beach Intl - MIA Miami
MYRMIA
Myrtle Beach Intl
Sun 12/20
7:03 pm-12:58 am
1 stop5h 55m
Miami
Sat 12/26
6:00 am-10:01 am
1 stop4h 01m
$487
Myrtle BeachMiami
MYR Myrtle Beach Intl - MIA Miami
MYRMIA
Myrtle Beach Intl
Sun 1/10
3:20 pm-10:05 pm
1 stop6h 45m
Miami
Thu 1/21
10:20 am-10:37 am
3 stops24h 17m
$638
Myrtle BeachMiami
MYR Myrtle Beach Intl - MIA Miami
MYRMIA
Myrtle Beach Intl
Wed 11/18
11:27 am-7:41 pm
1 stop8h 14m
Miami
Mon 11/23
9:00 am-10:21 am
2 stops25h 21m
$643
Myrtle BeachMiami
MYR Myrtle Beach Intl - MIA Miami
MYRMIA
Myrtle Beach Intl
Sat 10/24
10:23 am-11:39 pm
2 stops13h 16m
Miami
Sun 11/1
8:00 am-5:11 pm
1 stop9h 11m
$695
Myrtle BeachMiami
MYR Myrtle Beach Intl - MIA Miami
MYRMIA
Myrtle Beach Intl
Sat 10/31
11:27 am-7:41 pm
1 stop8h 14m
Miami
Sun 11/8
9:00 am-10:21 am
2 stops25h 21m
$749
Myrtle BeachMiami
MYR Myrtle Beach Intl - MIA Miami
MYRMIA
Myrtle Beach Intl
Thu 10/1
1:25 pm-11:05 pm
2 stops9h 40m
Miami
Sun 10/4
6:05 am-3:25 pm
2 stops9h 20m
$758
Showing 1-10 of 20 resultsSorted by cheapest first
Best time to book a flight from Myrtle Beach to Key Largo
Have a flexible travel schedule? Discover the best time to fly to Key Largo from Myrtle Beach with our price prediction graph.
MYR-MIA
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.
Cheapflights Insights
Everything you need to know about your flight from Myrtle Beach to Key Largo
MYR-KE9
MYR-MIA
What is the cheapest time of day to fly from MYR to KE9?
Find hourly flight availability from Myrtle Beach to Key Largo. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated September 1, 2026.
Unlike at noon, when flights are generally more expensive, you can save up to 30% on flights from Myrtle Beach to Key Largo by exploring options for tickets in the morning.
How much does it cost to fly round-trip from Myrtle Beach to Key Largo?
Airfare is below average for this route at the moment.
Myrtle Beach to Key Largo flights typically cost between $353 and $443 in September.The cheapest round-trip price found within the last 5 days was $215 on Frontier (Sep 24-Sep 26).
What is the cheapest day to fly from Myrtle Beach to Key Largo?
Use this chart to determine the cheapest time to fly round-trip from Myrtle Beach to Key Largo. Price data was last updated on August 29, 2026.
Travelers seeking maximum savings on their Myrtle Beach to Key Largo flight should consider departing on Sunday at noon when fares are most often at their lowest. Monday evenings flights should be avoided if possible as fares are typically the most expensive at this time.
Reviews of airlines servicing Key Largo
Get insights into the airlines that provide service to Key Largo. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Key Largo. Reviews last updated September 1, 2026.
Get a feel of what it's like to fly with Southwest,Delta, andAmerican Airlines from Myrtle Beach to Key Largo by reading reviews from past customers. Users have also rated airlines in terms of entertainment options, comfort, food, crew/service, and boarding process.
Food
7.0
Comfort
8.0
Boarding
8.1
Overall
8.0
Entertainment
7.5
Crew
8.6
Reviews
1 / 20
6.0
GoodScott,Feb 2026
HOU - FLL
Food
7.0
Comfort
8.0
Boarding
8.1
Overall
8.0
Entertainment
7.5
Crew
8.6
Reviews
1 / 20
6.0
GoodScott,Feb 2026
HOU - FLL
Food
7.0
Comfort
8.0
Boarding
8.1
Overall
8.0
Entertainment
7.5
Crew
8.6
Reviews
1 / 20
6.0
GoodScott,Feb 2026
HOU - FLL
Food
7.0
Comfort
8.0
Boarding
8.1
Overall
8.0
Entertainment
7.5
Crew
8.6
Reviews
1 / 20
6.0
GoodScott,Feb 2026
HOU - FLL
Related info for your journey
Find useful and relevant information for your journey from Myrtle Beach to Key Largo. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.
Browse thousands of different options on Cheapflights for your next trip
Toggle through the tabs below to find thousands of options on Cheapflights for your next trip.
Alternative routes
Complete your trip
Flights by cabin class
Other flight options
Other flights from Myrtle Beach
Popular flights
Top destinations
Alternative routes for Myrtle Beach to Key Largo
See prices for flight routes from nearby airports that may be better suited for you.
Complete your trip
Complete your trip to Key Largo by adding a car rental and/or hotel reservation to your travel itinerary.
Search flights from Myrtle Beach to Key Largo by cabin class
Find flights from Myrtle Beach to Key Largo, based on your preferred cabin class, be it economy, premium economy, business, or first class.
Myrtle Beach and Key Largo flights
Browse other Myrtle Beach and Key Largo flight options. Last updated on September 1, 2026.
Other flights from Myrtle Beach
Browse through other flights departing from Myrtle Beach. Flights are based on user searches made on Cheapflights and were last updated on September 1, 2026.
Popular flight searches
Check out other popular destinations found by fellow travelers in 2026
Myrtle Beach to Key Largo flights
Consider these flights traveling from Myrtle Beach to Key Largo.
Top 4 airlines flying from Myrtle Beach to Key Largo
Discover the top 4 airlines that operate flights from Myrtle Beach to Key Largo. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 7,457,451 searches. Data last updated September 1, 2026.
| Airline | Cheapest | Average | Flexibility | On-time |
|---|---|---|---|---|
| Cheapest$100 | Average$490 | FlexibilityNo cancel fee | On-timeN/A | |
| Cheapest$115 | Average$199 | FlexibilityNo cancel fee | On-timeN/A | |
| Cheapest$259 | Average$426 | FlexibilityNo cancel fee | On-time71% | |
| Cheapest$302 | Average$547 | FlexibilityNo cancel fee | On-time63% |