$131+ Cheap flights from Myrtle Beach (MYR) to Key Largo, FL
This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 9/24. Fares are subject to change and may not be available on all flights or dates of travel.
MYR — MIA
Sep 25 — Oct 21
Round-trip
1 adult, Economy
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Find cheap flights from Myrtle Beach to Key Largo with Cheapflights
1. Tell us where you want to go
Enter your travel information like dates, passengers, trip type (one-way or round trip), and preferred cabin class then click “Find deals”2. Select your favorite providers
We find the providers serving your travel needs. Choose up to four travel providers to compare side-by-side for flights, hotels, or car rentals.3. Compare prices and book
Review each provider’s pricing and select the best option for you! Book through your favorite provider’s website for a seamless experience.Cheap flight deals from Myrtle Beach to Key Largo
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Last-minute
One-way
Cheapest flights from Myrtle Beach to Key LargoExplore the most affordable flight options available from Myrtle Beach to Key Largo. Find the lowest fares from popular airlines and budget airlines, with prices last updated on August 26, 2026.
Explore the most affordable flight options available from Myrtle Beach to Key Largo. Find the lowest fares from popular airlines and budget airlines, with prices last updated on August 26, 2026.
This Frontier deal was found by Cheapflights users on 8/24. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Frontier is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/159:32 am -
1 stop10h 13m
Sat 10/178:50 pm -
1 stop11h 57m
Deal found 8/24![Frontier logo]()
$230
This Kiwi.com deal was found by Cheapflights users on 8/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 9/305:58 pm -
2 stops26h 35m
Sat 10/318:56 pm -
1 stop12h 55m
Deal found 8/21![Multiple Airlines logo]()
$251
This Expedia deal was found by Cheapflights users on 8/24. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Expedia is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 9/109:37 am -
1 stop10h 08m
Sat 9/128:50 pm -
1 stop12h 02m
Deal found 8/24![Frontier logo]()
$270
This Kiwi.com deal was found by Cheapflights users on 8/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 9/109:37 am -
1 stop10h 08m
Tue 9/155:32 am -
2 stops32h 13m
Deal found 8/21![Multiple Airlines logo]()
$273
This Kiwi.com deal was found by Cheapflights users on 8/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 9/109:37 am -
1 stop10h 08m
Fri 9/255:34 pm -
2 stops44h 22m
Deal found 8/21![Multiple Airlines logo]()
$275
This Kiwi.com deal was found by Cheapflights users on 8/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/159:32 am -
1 stop10h 13m
Mon 10/1910:55 pm -
2 stops36h 49m
Deal found 8/25![Multiple Airlines logo]()
$285
This Kiwi.com deal was found by Cheapflights users on 8/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 9/186:12 pm -
2 stops26h 26m
Sat 9/268:50 pm -
1 stop12h 02m
Deal found 8/25![Multiple Airlines logo]()
$286
This Kiwi.com deal was found by Cheapflights users on 8/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 11/89:36 am -
1 stop10h 15m
Fri 11/1310:55 pm -
2 stops33h 56m
Deal found 8/22![Frontier logo]()
$294
This Frontier deal was found by Cheapflights users on 8/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Frontier is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/19:37 am -
1 stop10h 08m
Wed 10/78:50 pm -
1 stop11h 57m
Deal found 8/22![Frontier logo]()
$295
This American Airlines deal was found by Cheapflights users on 8/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 9/306:30 am -
1 stop4h 46m
Sat 10/318:40 am -
1 stop4h 51m
Deal found 8/21![American Airlines logo]()
$297
This Kiwi.com deal was found by Cheapflights users on 8/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/19:37 am -
1 stop10h 08m
Mon 10/59:30 pm -
2 stops38h 14m
Deal found 8/22![Multiple Airlines logo]()
$299
Best flights from Myrtle Beach to Key LargoDiscover carefully curated flight deals from Myrtle Beach to Key Largo that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated August 26, 2026.
Discover carefully curated flight deals from Myrtle Beach to Key Largo that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated August 26, 2026.
This Delta deal was found by Cheapflights users on 8/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 10/136:58 pm -
1 stop5h 55m
Wed 10/146:04 am -
1 stop4h 03m
Deal found 8/21![Delta logo]()
$297
This Southwest deal was found by Cheapflights users on 8/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/13:55 pm -
2 stops7h 10m
Mon 10/56:25 am -
1 stop8h 55m
Deal found 8/21![Southwest logo]()
$308
This Delta deal was found by Cheapflights users on 8/24. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/16:56 pm -
1 stop5h 59m
Mon 10/56:00 am -
1 stop4h 07m
Deal found 8/24![Delta logo]()
$309
This Southwest deal was found by Cheapflights users on 8/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 10/266:15 am -
2 stops9h 15m
Sat 11/76:45 am -
2 stops10h 35m
Deal found 8/22![Southwest logo]()
$319
This Southwest deal was found by Cheapflights users on 8/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 9/242:30 pm -
2 stops7h 40m
Mon 9/287:00 am -
2 stops7h 45m
Deal found 8/22![Southwest logo]()
$319
This Southwest deal was found by Cheapflights users on 8/24. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 9/2311:00 am -
2 stops9h 05m
Wed 9/309:15 am -
2 stops10h 00m
Deal found 8/24![Southwest logo]()
$327
This Delta deal was found by Cheapflights users on 8/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 11/196:51 pm -
1 stop6h 05m
Mon 11/236:00 am -
1 stop4h 07m
Deal found 8/25![Delta logo]()
$363
This Delta deal was found by Cheapflights users on 8/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 11/216:51 pm -
1 stop6h 06m
Mon 11/236:00 am -
1 stop4h 07m
Deal found 8/25![Delta logo]()
$363
This Southwest deal was found by Cheapflights users on 8/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 9/252:30 pm -
1 stop6h 20m
Mon 9/287:00 am -
2 stops7h 45m
Deal found 8/21![Southwest logo]()
$348
This Southwest deal was found by Cheapflights users on 8/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 10/202:10 pm -
2 stops8h 00m
Sun 10/256:20 am -
1 stop9h 05m
Deal found 8/25![Southwest logo]()
$364
Last-minute flights from Myrtle Beach to Key LargoDiscover last-minute flight deals from Myrtle Beach to Key Largo. Data last updated August 26, 2026 and is based on user searches.
Discover last-minute flight deals from Myrtle Beach to Key Largo. Data last updated August 26, 2026 and is based on user searches.
This Expedia deal was found by Cheapflights users on 8/24. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Expedia is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 9/109:37 am -
1 stop10h 08m
Sat 9/128:50 pm -
1 stop12h 02m
Deal found 8/24![Frontier logo]()
$270
This Kiwi.com deal was found by Cheapflights users on 8/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 9/109:37 am -
1 stop10h 08m
Tue 9/155:32 am -
2 stops32h 13m
Deal found 8/21![Multiple Airlines logo]()
$273
This Kiwi.com deal was found by Cheapflights users on 8/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 9/109:37 am -
1 stop10h 08m
Fri 9/255:34 pm -
2 stops44h 22m
Deal found 8/21![Multiple Airlines logo]()
$275
This American Airlines deal was found by Cheapflights users on 8/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 9/1412:10 pm -
1 stop6h 34m
Fri 9/189:59 am -
1 stop6h 56m
Deal found 8/21![American Airlines logo]()
$311
This Kiwi.com deal was found by Cheapflights users on 8/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 9/186:12 pm -
2 stops26h 26m
Sat 9/268:50 pm -
1 stop12h 02m
Deal found 8/25![Multiple Airlines logo]()
$286
This American Airlines deal was found by Cheapflights users on 8/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 9/225:45 pm -
1 stop6h 14m
Thu 10/19:55 am -
1 stop7h 00m
Deal found 8/23![American Airlines logo]()
$309
This Southwest deal was found by Cheapflights users on 8/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 9/242:30 pm -
1 stop6h 20m
Mon 9/287:00 am -
2 stops7h 45m
Deal found 8/22![Southwest logo]()
$314
This Kiwi.com deal was found by Cheapflights users on 8/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 9/305:58 pm -
2 stops26h 35m
Sat 10/318:56 pm -
1 stop12h 55m
Deal found 8/21![Multiple Airlines logo]()
$251
This American Airlines deal was found by Cheapflights users on 8/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 9/306:30 am -
1 stop4h 46m
Sat 10/318:40 am -
1 stop4h 51m
Deal found 8/21![American Airlines logo]()
$297
This Southwest deal was found by Cheapflights users on 8/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 9/308:15 am -
2 stops12h 00m
Sat 10/316:25 am -
2 stops8h 50m
Deal found 8/21![Southwest logo]()
$307
One-way flights from Myrtle Beach to Key LargoSearch for one-way flight options from Myrtle Beach to Key Largo. Find affordable one-way fares based on user searches. Data last updated August 26, 2026.
Search for one-way flight options from Myrtle Beach to Key Largo. Find affordable one-way fares based on user searches. Data last updated August 26, 2026.
This Priceline deal was found by Cheapflights users on 8/24. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Priceline is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 9/249:37 am -
1 stop10h 08m
Deal found 8/24![Frontier logo]()
$131
This Kiwi.com deal was found by Cheapflights users on 8/24. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/26:12 pm -
2 stops26h 26m
Deal found 8/24![Multiple Airlines logo]()
$133
This Kiwi.com deal was found by Cheapflights users on 8/24. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 9/1510:50 am -
2 stops33h 48m
Deal found 8/24![Multiple Airlines logo]()
$144
This Kiwi.com deal was found by Cheapflights users on 8/24. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 10/35:58 pm -
2 stops40h 32m
Deal found 8/24![Multiple Airlines logo]()
$147
This Kiwi.com deal was found by Cheapflights users on 8/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/96:12 pm -
2 stops27h 17m
Deal found 8/25![Multiple Airlines logo]()
$149
This Southwest deal was found by Cheapflights users on 8/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 11/710:35 am -
2 stops10h 05m
Deal found 8/21![Southwest logo]()
$154
This Delta deal was found by Cheapflights users on 8/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 2/136:45 pm -
1 stop6h 07m
Deal found 8/25![Delta logo]()
$155
This Kiwi.com deal was found by Cheapflights users on 8/24. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 10/72:40 pm -
2 stops19h 35m
Deal found 8/24![Multiple Airlines logo]()
$156
This Kiwi.com deal was found by Cheapflights users on 8/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 11/75:58 pm -
3 stops27h 51m
Deal found 8/21![Multiple Airlines logo]()
$158
Find flight deals from Myrtle Beach to Key Largo
Keep the following information in mind while searching for Myrtle Beach to Key Largo flight deals. Data was last updated August 26, 2026.
Most accurate provider | FlightHub 3 stars |
|---|---|
Most trusted provider | FlightHub 3 stars |
Round-trip from | $230 (Frontier) |
One-way from | $131 (Priceline) |
Popular in | July |
Cheapest in | August |
Average price | $324 |
Cheapflights Fare Finder
Customize your flight search to find flights from Myrtle Beach to Key Largo that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 7,457,451 searches. Data last updated August 26, 2026.
Use the filters below to find and compare flights from Myrtle Beach to Key Largo that are best for you.
Fly from
Fly to
Route
Depart
Return
Cheapest round-trip
Quickest round-trip
Myrtle BeachMiami
MYR Myrtle Beach Intl - MIA Miami
MYRMIA
Myrtle Beach Intl
Tue 10/13
6:58 pm-12:53 am
1 stop5h 55m
Miami
Wed 10/14
6:04 am-10:07 am
1 stop4h 03m
$297
Myrtle BeachMiami
MYR Myrtle Beach Intl - MIA Miami
MYRMIA
Myrtle Beach Intl
Thu 10/1
3:55 pm-11:05 pm
2 stops7h 10m
Miami
Mon 10/5
6:25 am-3:20 pm
1 stop8h 55m
$308
Myrtle BeachMiami
MYR Myrtle Beach Intl - MIA Miami
MYRMIA
Myrtle Beach Intl
Thu 10/1
6:56 pm-12:55 am
1 stop5h 59m
Miami
Mon 10/5
6:00 am-10:07 am
1 stop4h 07m
$309
Myrtle BeachMiami
MYR Myrtle Beach Intl - MIA Miami
MYRMIA
Myrtle Beach Intl
Mon 10/26
6:15 am-3:30 pm
2 stops9h 15m
Miami
Sat 11/7
6:45 am-5:20 pm
2 stops10h 35m
$319
Myrtle BeachMiami
MYR Myrtle Beach Intl - MIA Miami
MYRMIA
Myrtle Beach Intl
Thu 9/24
2:30 pm-10:10 pm
2 stops7h 40m
Miami
Mon 9/28
7:00 am-2:45 pm
2 stops7h 45m
$319
Myrtle BeachMiami
MYR Myrtle Beach Intl - MIA Miami
MYRMIA
Myrtle Beach Intl
Wed 9/23
11:00 am-8:05 pm
2 stops9h 05m
Miami
Wed 9/30
9:15 am-7:15 pm
2 stops10h 00m
$327
Myrtle BeachMiami
MYR Myrtle Beach Intl - MIA Miami
MYRMIA
Myrtle Beach Intl
Fri 9/25
2:30 pm-8:50 pm
1 stop6h 20m
Miami
Mon 9/28
7:00 am-2:45 pm
2 stops7h 45m
$348
Myrtle BeachMiami
MYR Myrtle Beach Intl - MIA Miami
MYRMIA
Myrtle Beach Intl
Thu 11/19
6:51 pm-12:56 am
1 stop6h 05m
Miami
Mon 11/23
6:00 am-10:07 am
1 stop4h 07m
$363
Myrtle BeachMiami
MYR Myrtle Beach Intl - MIA Miami
MYRMIA
Myrtle Beach Intl
Sat 11/21
6:51 pm-12:57 am
1 stop6h 06m
Miami
Mon 11/23
6:00 am-10:07 am
1 stop4h 07m
$363
Myrtle BeachMiami
MYR Myrtle Beach Intl - MIA Miami
MYRMIA
Myrtle Beach Intl
Tue 10/20
2:10 pm-10:10 pm
2 stops8h 00m
Miami
Sun 10/25
6:20 am-3:25 pm
1 stop9h 05m
$364
Showing 1-10 of 18 resultsSorted by cheapest first
Best time to book a flight from Myrtle Beach to Key Largo
Have a flexible travel schedule? Discover the best time to fly to Key Largo from Myrtle Beach with our price prediction graph.
MYR-MIA
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.
Cheapflights Insights
Everything you need to know about your flight from Myrtle Beach to Key Largo
MYR-KE9
MYR-MIA
What is the cheapest time of day to fly from MYR to KE9?
Find hourly flight availability from Myrtle Beach to Key Largo. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated August 26, 2026.
Unlike at noon, when flights are generally more expensive, you can save up to 27% on flights from Myrtle Beach to Key Largo by exploring options for tickets in the morning.
How much does it cost to fly round-trip from Myrtle Beach to Key Largo?
Airfare is below average for this route at the moment.
Myrtle Beach to Key Largo flights typically cost between $320 and $416 in October.The cheapest round-trip price found within the last 5 days was $230 on Frontier (Oct 15-Oct 17).
What is the cheapest day to fly from Myrtle Beach to Key Largo?
Use this chart to determine the cheapest time to fly round-trip from Myrtle Beach to Key Largo. Price data was last updated on August 22, 2026.
Travelers seeking maximum savings on their Myrtle Beach to Key Largo flight should consider departing on Sunday at noon when fares are most often at their lowest. Monday evenings flights should be avoided if possible as fares are typically the most expensive at this time.
Reviews of airlines servicing Key Largo
Get insights into the airlines that provide service to Key Largo. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Key Largo. Reviews last updated August 26, 2026.
Get a feel of what it's like to fly with Southwest,Delta, andAmerican Airlines from Myrtle Beach to Key Largo by reading reviews from past customers. Users have also rated airlines in terms of entertainment options, comfort, food, crew/service, and boarding process.
Entertainment
7.5
Boarding
8.1
Crew
8.6
Overall
8.0
Food
7.0
Comfort
8.0
Reviews
1 / 20
6.0
GoodScott,Feb 2026
HOU - FLL
Entertainment
7.5
Boarding
8.1
Crew
8.6
Overall
8.0
Food
7.0
Comfort
8.0
Reviews
1 / 20
6.0
GoodScott,Feb 2026
HOU - FLL
Entertainment
7.5
Boarding
8.1
Crew
8.6
Overall
8.0
Food
7.0
Comfort
8.0
Reviews
1 / 20
6.0
GoodScott,Feb 2026
HOU - FLL
Entertainment
7.5
Boarding
8.1
Crew
8.6
Overall
8.0
Food
7.0
Comfort
8.0
Reviews
1 / 20
6.0
GoodScott,Feb 2026
HOU - FLL
Related info for your journey
Find useful and relevant information for your journey from Myrtle Beach to Key Largo. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.
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Search flights from Myrtle Beach to Key Largo by cabin class
Find flights from Myrtle Beach to Key Largo, based on your preferred cabin class, be it economy, premium economy, business, or first class.
Myrtle Beach and Key Largo flights
Browse other Myrtle Beach and Key Largo flight options. Last updated on August 26, 2026.
Other flights from Myrtle Beach
Browse through other flights departing from Myrtle Beach. Flights are based on user searches made on Cheapflights and were last updated on August 26, 2026.
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Myrtle Beach to Key Largo flights
Consider these flights traveling from Myrtle Beach to Key Largo.
Top 4 airlines flying from Myrtle Beach to Key Largo
Discover the top 4 airlines that operate flights from Myrtle Beach to Key Largo. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 7,457,451 searches. Data last updated August 26, 2026.
| Airline | Cheapest | Average | Flexibility | On-time |
|---|---|---|---|---|
| Cheapest$100 | Average$489 | FlexibilityNo cancel fee | On-timeN/A | |
| Cheapest$114 | Average$202 | FlexibilityNo cancel fee | On-timeN/A | |
| Cheapest$259 | Average$421 | FlexibilityNo cancel fee | On-time71% | |
| Cheapest$302 | Average$547 | FlexibilityNo cancel fee | On-time63% |