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Key Largo

$120+ Cheap flights from Harrisburg (MDT) to Key Largo, FL

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 12/14. Fares are subject to change and may not be available on all flights or dates of travel.
MDT — MIA
Oct 17 — Oct 241
Fri 10/17
Fri 10/24
1 adult, Economy
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Cheapflights Tip: The best prices from Harrisburg to Key Largo are usually found in September or November, booked 23 days in advance, depart on a Thursday or Friday and return on a Wednesday

Cheap flight deals from Harrisburg to Key Largo

Keep the following information in mind while searching for Harrisburg to Key Largo flight deals. Data was last updated September 17, 2025.

Round-trip from

$259
(American Airlines)

One-way from

$120
(Kiwi.com)

Popular in

January

Cheapest in

September

Average price

$258
From Harrisburg to Key Largo
Search Deals
One-way flight from Harrisburg to Key Largo
Search Deals
Highest demand for flights based on searches. 8% potential increase in price ($45 potential increase over avg. RT price).
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Cheapest flight prices on average. 3% potential price decrease ($17 potential savings vs. average RT price).
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Average for round-trip flights in September 2025
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Find flight deals from Harrisburg to Key Largo

Cheapest flights from Harrisburg to Key Largo
Explore the most affordable flight options available from Harrisburg to Key Largo. Find the lowest fares from popular airlines and budget airlines, with prices last updated on September 17, 2025.

This American Airlines deal was found by Cheapflights users on 9/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 11/1311:23 amMDT - MIA
1 stop7h 25mAmerican Airlines
Tue 11/187:01 amMIA - MDT
1 stop5h 24mAmerican Airlines
Deal found 9/16$259
This American Airlines deal was found by Cheapflights users on 9/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 11/285:00 amMDT - MIA
1 stop4h 59mAmerican Airlines
Sat 12/66:00 amMIA - MDT
1 stop5h 12mAmerican Airlines
Deal found 9/15$274
This Frontier deal was found by Cheapflights users on 9/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Frontier is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/311:07 amMDT - MIA
2 stops10h 31mFrontier
Fri 10/1010:42 amMIA - MDT
2 stops8h 53mFrontier
Deal found 9/15$280
This American Airlines deal was found by Cheapflights users on 9/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/236:00 amMDT - MIA
1 stop5h 38mAmerican Airlines
Sun 10/265:18 amMIA - MDT
1 stop5h 42mAmerican Airlines
Deal found 9/16$304
This American Airlines deal was found by Cheapflights users on 9/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 11/15:27 pmMDT - MIA
1 stop6h 05mAmerican Airlines
Sun 11/98:35 amMIA - MDT
1 stop6h 19mAmerican Airlines
Deal found 9/15$319
This Delta deal was found by Cheapflights users on 9/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/176:25 pmMDT - MIA
1 stop6h 04mDelta
Tue 10/214:35 pmMIA - MDT
1 stop6h 33mDelta
Deal found 9/15$324
This American Airlines deal was found by Cheapflights users on 9/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/34:45 pmMDT - MIA
1 stop4h 44mAmerican Airlines
Fri 10/106:50 amMIA - MDT
1 stop4h 50mAmerican Airlines
Deal found 9/15$326
This American Airlines deal was found by Cheapflights users on 9/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 10/158:00 amMDT - MIA
1 stop5h 44mAmerican Airlines
Mon 10/206:20 amMIA - MDT
1 stop6h 47mAmerican Airlines
Deal found 9/16$343
This American Airlines deal was found by Cheapflights users on 9/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/99:33 amMDT - MIA
1 stop7h 15mAmerican Airlines
Sun 10/126:20 amMIA - MDT
1 stop6h 47mAmerican Airlines
Deal found 9/15$350
This Kiwi.com deal was found by Cheapflights users on 9/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 12/119:30 amMDT - MIA
1 stop7h 56mMultiple Airlines
Sun 12/1411:28 amMIA - MDT
2 stops23h 17mMultiple Airlines
Deal found 9/15$354
This Frontier deal was found by Cheapflights users on 9/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Frontier is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 9/2611:07 amMDT - MIA
2 stops10h 31mFrontier
Sun 9/284:01 pmMIA - MDT
2 stops18h 01mFrontier
Deal found 9/16$356
This American Airlines deal was found by Cheapflights users on 9/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 11/279:40 amMDT - MIA
1 stop5h 41mAmerican Airlines
Sat 12/69:30 amMIA - MDT
1 stop7h 36mAmerican Airlines
Deal found 9/16$359

Cheapflights Fare Finder

 
Customize your flight search to find flights from Harrisburg to Key Largo that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated September 17, 2025.
Use the filters below to find and compare flights from Harrisburg to Key Largo that are best for you.

Fly from

Harrisburg

Fly to

Key Largo

Route

Depart

Return

Price

HarrisburgMiami

MDT - MIA

MDTMIA

Harrisburg

Wed 12/3

5:40 am-12:31 pm

1 stop6h 51m

Miami

Mon 12/8

7:19 pm-11:50 pm

1 stop4h 31m

$259

HarrisburgMiami

MDT - MIA

MDTMIA

Harrisburg

Fri 11/28

5:00 am-9:59 am

1 stop4h 59m

Miami

Sat 12/6

7:10 pm-12:19 am

1 stop5h 09m

$259

HarrisburgMiami

MDT - MIA

MDTMIA

Harrisburg

Tue 12/2

2:55 pm-9:34 pm

1 stop6h 39m

Miami

Thu 12/11

5:35 pm-10:15 pm

1 stop4h 40m

$304

HarrisburgMiami

MDT - MIA

MDTMIA

Harrisburg

Fri 10/17

6:25 pm-12:29 am

1 stop6h 04m

Miami

Tue 10/21

4:35 pm-11:08 pm

1 stop6h 33m

$324

HarrisburgMiami

MDT - MIA

MDTMIA

Harrisburg

Thu 11/13

11:23 am-6:48 pm

1 stop7h 25m

Miami

Sun 11/16

6:00 am-10:53 am

1 stop4h 53m

$343

HarrisburgMiami

MDT - MIA

MDTMIA

Harrisburg

Thu 11/27

9:40 am-3:21 pm

1 stop5h 41m

Miami

Sat 12/6

11:25 am-5:06 pm

1 stop5h 41m

$359

HarrisburgMiami

MDT - MIA

MDTMIA

Harrisburg

Tue 9/30

6:15 am-11:16 am

1 stop5h 01m

Miami

Sat 10/4

12:27 pm-7:57 pm

1 stop7h 30m

$369

HarrisburgMiami

MDT - MIA

MDTMIA

Harrisburg

Thu 12/11

3:46 pm-8:56 pm

1 stop5h 10m

Miami

Sun 12/14

9:30 am-2:52 pm

1 stop5h 22m

$375

HarrisburgMiami

MDT - MIA

MDTMIA

Harrisburg

Fri 12/5

4:25 pm-11:52 pm

1 stop7h 27m

Miami

Sun 12/7

7:10 pm-12:18 am

1 stop5h 08m

$375

HarrisburgMiami

MDT - MIA

MDTMIA

Harrisburg

Sun 11/2

2:55 pm-10:24 pm

1 stop7h 29m

Miami

Mon 11/10

5:45 am-10:29 am

1 stop4h 44m

$388

Flights are sorted by cheapest round-trip flights first.

Deals found on 9/15

Showing 1-10 of 20 results
1
2

Best time to book a flight from Harrisburg to Key Largo

Have a flexible travel schedule? Discover the best time to fly to Key Largo from Harrisburg with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Harrisburg to Key Largo

How far ahead should I book a flight from Harrisburg to Key Largo?

Use this chart to determine the optimal time to book a round-trip flight from Harrisburg to Key Largo. Price data was last updated on September 12, 2025.

Booking 23 days in advance of your planned departure date is, on average, the best time to get cheap flights from Harrisburg to Key Largo. The general trend is that the closer you book to the departure date, the more expensive your flight will be.

What is the cheapest month to book a flight from Harrisburg to Key Largo?

Currently, September is the cheapest month in which you can book a flight from Harrisburg to Key Largo (average of $232). Flying from Harrisburg to Key Largo in March is currently the most expensive (average of $289). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

What is the cheapest time of day to fly from MDT to KE9?

Find hourly flight availability from Harrisburg to Key Largo. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated September 17, 2025.

Regardless of the time of day you decide to fly, the ticket price will remain around the same. Book flights from Harrisburg to Key Largo as you normally would.

What is the cheapest day to fly from Harrisburg to Key Largo?

Use this chart to determine the cheapest time to fly round-trip from Harrisburg to Key Largo. Price data was last updated on December 16, 2024.

Travelers seeking maximum savings on their Harrisburg to Key Largo flight should consider departing on Wednesday afternoons when fares are most often at their lowest. Wednesday mornings flights should be avoided if possible as fares are typically the most expensive at this time.

Reviews of airlines servicing Key Largo

Get insights into the airlines that provide service to Key Largo. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Key Largo. Reviews last updated September 17, 2025.
See what other customers who have flown with Delta, United Airlines, and American Airlines from Harrisburg to Key Largo have to say. You can also see how each airline compares in terms of entertainment options, comfort, food, crew/service, and boarding process.
Delta
8.0
Very good
7,961 reviews

Boarding

8.2

Crew

8.5

Overall

8.0

Food

7.3

Comfort

7.9

Entertainment

7.9

Reviews

1 / 20
2.0
Mediocre

Joseph,Aug 2023

MSP - MCO

Even if you have delta comfort plus, they will move your overhead bag. One of the perks for upgrading is that you have dedicated space for your carry on with comfort plus with delta. They moved my carry on luggage (3) compartments back and put in bags for other passengers that should have gone under their respective seats. When deboarding the plane, there was no help from anyone to retrieve my luggage back several rows. Delta is turning into pure garbage.
Delta
8.0
Very good
7,961 reviews
Delta
8.0
Very good
7,961 reviews

Boarding

8.2

Crew

8.5

Overall

8.0

Food

7.3

Comfort

7.9

Entertainment

7.9

Reviews

1 / 20
2.0
Mediocre

Joseph,Aug 2023

MSP - MCO

Even if you have delta comfort plus, they will move your overhead bag. One of the perks for upgrading is that you have dedicated space for your carry on with comfort plus with delta. They moved my carry on luggage (3) compartments back and put in bags for other passengers that should have gone under their respective seats. When deboarding the plane, there was no help from anyone to retrieve my luggage back several rows. Delta is turning into pure garbage.
United Airlines
7.4
Good
8,926 reviews
Delta
8.0
Very good
7,961 reviews

Boarding

8.2

Crew

8.5

Overall

8.0

Food

7.3

Comfort

7.9

Entertainment

7.9

Reviews

1 / 20
2.0
Mediocre

Joseph,Aug 2023

MSP - MCO

Even if you have delta comfort plus, they will move your overhead bag. One of the perks for upgrading is that you have dedicated space for your carry on with comfort plus with delta. They moved my carry on luggage (3) compartments back and put in bags for other passengers that should have gone under their respective seats. When deboarding the plane, there was no help from anyone to retrieve my luggage back several rows. Delta is turning into pure garbage.
American Airlines
7.2
Good
10,000 reviews
Delta
8.0
Very good
7,961 reviews

Boarding

8.2

Crew

8.5

Overall

8.0

Food

7.3

Comfort

7.9

Entertainment

7.9

Reviews

1 / 20
2.0
Mediocre

Joseph,Aug 2023

MSP - MCO

Even if you have delta comfort plus, they will move your overhead bag. One of the perks for upgrading is that you have dedicated space for your carry on with comfort plus with delta. They moved my carry on luggage (3) compartments back and put in bags for other passengers that should have gone under their respective seats. When deboarding the plane, there was no help from anyone to retrieve my luggage back several rows. Delta is turning into pure garbage.
Allegiant Air
7.2
Good
699 reviews
Delta
8.0
Very good
7,961 reviews

Boarding

8.2

Crew

8.5

Overall

8.0

Food

7.3

Comfort

7.9

Entertainment

7.9

Reviews

1 / 20
2.0
Mediocre

Joseph,Aug 2023

MSP - MCO

Even if you have delta comfort plus, they will move your overhead bag. One of the perks for upgrading is that you have dedicated space for your carry on with comfort plus with delta. They moved my carry on luggage (3) compartments back and put in bags for other passengers that should have gone under their respective seats. When deboarding the plane, there was no help from anyone to retrieve my luggage back several rows. Delta is turning into pure garbage.

Related info for your journey

Find useful and relevant information for your journey from Harrisburg to Key Largo. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • What airport do you fly from for flights from Harrisburg to Key Largo?

    Harrisburg (MDT), located 8.5 mi from the city center, is the airport you fly out of when you book flights from Harrisburg to Key Largo. 4 airlines have flights from Harrisburg to Key Largo on a regular basis. Booking flights from Harrisburg to Key Largo should not be difficult; the airport handles an average of 0 outbound flights to Key Largo per day.

  • How long is the flight from Harrisburg to Key Largo?

    Airlines like American Airlines and Delta fly from Harrisburg to Key Largo in about 6h 04m. The time it takes to get you to your destination can typically vary by up to 47m. Harrisburg and Key Largo are separated by a distance of 1015 mi. Both multi-stop and nonstop flights can be found to your destination and back.

  • Can I find deals for flights from Harrisburg to Key Largo that include hotel bookings?

    Yes. In addition to deals on Harrisburg to Key Largo flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Harrisburg to Key Largo?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Harrisburg to Key Largo.

  • Can I find deals for business class flights from Harrisburg to Key Largo?

    Yes. Cheapflights offers flight deals from Harrisburg to Key Largo by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Harrisburg to Key Largo?

    Currently, September is the cheapest month in which you can book a flight from Harrisburg to Key Largo (average of $232). Flying from Harrisburg to Key Largo in March is currently the most expensive (average of $289). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

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Top 4 airlines flying from Harrisburg to Key Largo

Discover the top 4 airlines that operate flights from Harrisburg to Key Largo. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated September 17, 2025.
AirlineCheapestAverageFlexibilityOn-time
Allegiant AirCheapest$99Average$215FlexibilityNo cancel feeOn-time88%
DeltaCheapest$244Average$420FlexibilityNo cancel feeOn-timeN/A
American AirlinesCheapest$258Average$431FlexibilityNo cancel feeOn-time71%
United AirlinesCheapest$329Average$586FlexibilityNo cancel feeOn-time69%

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