HomeSearch by dateVacation packagesHotelsFlight dealsCar rentalTravel tips & news
Key Largo

$100+ Cheap flights from Columbia (CAE) to Key Largo, FL

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 2/27. Fares are subject to change and may not be available on all flights or dates of travel.
CAE — MIA
Mar 14 — Mar 211
Sat 3/14
Sat 3/21
1 adult, Economy
We work with more than 300 partners to bring you better travel deals

Find cheap flights from Columbia to Key Largo with Cheapflights

1. Tell us where you want to go

Enter your travel information like dates, passengers, trip type (one-way or round trip), and preferred cabin class then click “Find deals”

2. Select your favorite providers

We find the providers serving your travel needs. Choose up to four travel providers to compare side-by-side for flights, hotels, or car rentals.

3. Compare prices and book

Review each provider’s pricing and select the best option for you! Book through your favorite provider’s website for a seamless experience.

Cheap flight deals from Columbia to Key Largo

Cheapest flights from Columbia to Key Largo
Explore the most affordable flight options available from Columbia to Key Largo. Find the lowest fares from popular airlines and budget airlines, with prices last updated on February 12, 2026.

This American Airlines deal was found by Cheapflights users on 2/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 5/236:00 am
CAE
-
MIA
Nonstop2h 05m
American Airlines
Sat 5/309:45 pm
MIA
-
CAE
Nonstop2h 14m
American Airlines
Deal found 2/9$249
This Delta deal was found by Cheapflights users on 2/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 4/1812:16 pm
CAE
-
MIA
1 stop4h 54m
Delta
Sat 4/257:04 am
MIA
-
CAE
1 stop4h 25m
Delta
Deal found 2/9$251
This Delta deal was found by Cheapflights users on 2/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 5/205:40 am
CAE
-
MIA
1 stop5h 13m
Delta
Wed 5/276:00 am
MIA
-
CAE
1 stop7h 04m
Delta
Deal found 2/11$260
This Delta deal was found by Cheapflights users on 2/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 5/281:50 pm
CAE
-
MIA
1 stop5h 57m
Delta
Thu 6/46:00 am
MIA
-
CAE
1 stop5h 08m
Delta
Deal found 2/9$269
This Delta deal was found by Cheapflights users on 2/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 4/277:14 pm
CAE
-
MIA
1 stop5h 40m
Delta
Sat 5/26:00 am
MIA
-
CAE
1 stop5h 29m
Delta
Deal found 2/9$270
This Delta deal was found by Cheapflights users on 2/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 7/206:50 pm
CAE
-
MIA
1 stop3h 55m
Delta
Sat 7/257:00 am
MIA
-
CAE
1 stop5h 28m
Delta
Deal found 2/9$279
This Delta deal was found by Cheapflights users on 2/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 2/285:35 am
CAE
-
MIA
1 stop3h 51m
Delta
Thu 3/127:05 am
MIA
-
CAE
1 stop6h 22m
Delta
Deal found 2/10$284
This Delta deal was found by Cheapflights users on 2/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 4/57:13 pm
CAE
-
MIA
1 stop5h 39m
Delta
Wed 4/157:04 am
MIA
-
CAE
1 stop4h 25m
Delta
Deal found 2/9$285
This American Airlines deal was found by Cheapflights users on 2/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 11/148:00 pm
CAE
-
MIA
1 stop4h 48m
American Airlines
Sun 11/226:00 am
MIA
-
CAE
1 stop4h 39m
American Airlines
Deal found 2/11$289
This Delta deal was found by Cheapflights users on 2/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 5/212:16 pm
CAE
-
MIA
1 stop4h 54m
Delta
Sun 5/107:00 am
MIA
-
CAE
1 stop4h 08m
Delta
Deal found 2/11$290
This Delta deal was found by Cheapflights users on 2/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 5/157:17 pm
CAE
-
MIA
1 stop5h 38m
Delta
Sun 5/246:00 am
MIA
-
CAE
1 stop5h 08m
Delta
Deal found 2/9$294

Find flight deals from Columbia to Key Largo

Keep the following information in mind while searching for Columbia to Key Largo flight deals. Data was last updated February 12, 2026.

Most accurate provider

FlightHub
3 stars

Most trusted provider

FlightHub
3 stars

Round-trip from

$251
(Delta)

One-way from

$100
(Kiwi.com)

Popular in

February

Cheapest in

August

Average price

$536
Provider with most accurate pricing for Columbia Metropolitan-Miami flight deals.
Search Deals
Provider most trusted by Cheapflights users for Columbia Metropolitan-Miami flights.
Search Deals
From Columbia Metropolitan to Key Largo
Search Deals
One-way flight from Columbia Metropolitan to Key Largo
Search Deals
Highest demand for flights based on searches. 15% potential increase in price ($83 potential increase over avg. RT price).
Search Deals
Cheapest flight prices on average. 2% potential price decrease ($9 potential savings vs. average RT price).
Search Deals
Average for round-trip flights in February 2026
Search Deals

Cheapflights Fare Finder

 
Customize your flight search to find flights from Columbia to Key Largo that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated February 12, 2026.
Use the filters below to find and compare flights from Columbia to Key Largo that are best for you.

Fly from

Columbia

Fly to

Key Largo

Route

Depart

Return

Price

ColumbiaMiami

CAE - MIA

CAEMIA

Columbia Metropolitan

Sat 4/18

12:16 pm-5:10 pm

1 stop4h 54m

Miami

Sat 4/25

7:04 am-11:29 am

1 stop4h 25m

$251

ColumbiaMiami

CAE - MIA

CAEMIA

Columbia Metropolitan

Sat 2/28

5:35 am-9:26 am

1 stop3h 51m

Miami

Thu 3/12

7:05 am-1:27 pm

1 stop6h 22m

$284

ColumbiaMiami

CAE - MIA

CAEMIA

Columbia Metropolitan

Sat 5/2

12:16 pm-5:10 pm

1 stop4h 54m

Miami

Sun 5/10

7:00 am-11:08 am

1 stop4h 08m

$290

ColumbiaMiami

CAE - MIA

CAEMIA

Columbia Metropolitan

Sun 4/5

7:13 pm-12:52 am

1 stop5h 39m

Miami

Wed 4/15

7:04 am-11:29 am

1 stop4h 25m

$295

ColumbiaMiami

CAE - MIA

CAEMIA

Columbia Metropolitan

Thu 4/9

7:13 pm-12:52 am

1 stop5h 39m

Miami

Thu 4/16

8:05 am-1:14 pm

1 stop5h 09m

$314

ColumbiaMiami

CAE - MIA

CAEMIA

Columbia Metropolitan

Wed 2/18

8:45 am-3:41 pm

1 stop6h 56m

Miami

Wed 2/25

8:15 am-2:21 pm

1 stop6h 06m

$319

ColumbiaMiami

CAE - MIA

CAEMIA

Columbia Metropolitan

Mon 2/16

6:50 pm-10:47 pm

1 stop3h 57m

Miami

Wed 2/25

8:15 am-12:00 pm

1 stop3h 45m

$334

ColumbiaMiami

CAE - MIA

CAEMIA

Columbia Metropolitan

Thu 2/26

3:09 pm-8:44 pm

1 stop5h 35m

Miami

Wed 3/11

6:27 pm-11:48 pm

1 stop5h 21m

$350

ColumbiaMiami

CAE - MIA

CAEMIA

Columbia Metropolitan

Thu 2/19

5:35 am-9:26 am

1 stop3h 51m

Miami

Wed 2/25

8:15 am-2:21 pm

1 stop6h 06m

$359

ColumbiaMiami

CAE - MIA

CAEMIA

Columbia Metropolitan

Fri 2/27

6:50 pm-12:53 am

1 stop6h 03m

Miami

Mon 3/2

7:15 am-12:00 pm

1 stop4h 45m

$369

Flights are sorted by cheapest round-trip flights first.

Deals found on 2/10

Showing 1-10 of 19 results
1
2

Best time to book a flight from Columbia to Key Largo

Have a flexible travel schedule? Discover the best time to fly to Key Largo from Columbia with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Columbia to Key Largo

How far ahead should I book a flight from Columbia to Key Largo?

Use this chart to determine the optimal time to book a round-trip flight from Columbia to Key Largo. Price data was last updated on February 6, 2026.

Booking 40 days in advance of your planned departure date is, on average, the best time to get cheap flights from Columbia to Key Largo. The general trend is that the closer you book to the departure date, the more expensive your flight will be.

What is the cheapest month to book a flight from Columbia to Key Largo?

Currently, March is the cheapest month in which you can book a flight from Columbia to Key Largo (average of $33). Flying from Columbia to Key Largo in April is currently the most expensive (average of $68). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

What is the cheapest time of day to fly from CAE to KE9?

Find hourly flight availability from Columbia to Key Largo. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated February 12, 2026.

It’s typically best to fly out from Columbia to Key Largo in the evening. Doing so could potentially save you 77% on the flight price compared to flying in the morning, which is usually more expensive.

Reviews of airlines servicing Key Largo

Get insights into the airlines that provide service to Key Largo. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Key Largo. Reviews last updated February 12, 2026.
Read through reviews of airlines operating flights from Columbia to Key Largo, such as Delta and American Airlines. Reviews also offer insight into each airline's entertainment options, comfort, food, crew/service, and boarding process.
Delta
7.9
Good
8,180 reviews

Boarding

8.1

Crew

8.5

Comfort

7.9

Overall

7.9

Entertainment

7.8

Food

7.2

Reviews

1 / 20
8.0
Excellent

Matthew,Oct 2025

GSP - ATL

This is always a full flight since it is the connecting route to primary destinations through Atlanta. That said, the crew handles the full load well. Not much more to say, it is a short flight with no in-flight services due to the length.
Delta
7.9
Good
8,180 reviews
Delta
7.9
Good
8,180 reviews

Boarding

8.1

Crew

8.5

Comfort

7.9

Overall

7.9

Entertainment

7.8

Food

7.2

Reviews

1 / 20
8.0
Excellent

Matthew,Oct 2025

GSP - ATL

This is always a full flight since it is the connecting route to primary destinations through Atlanta. That said, the crew handles the full load well. Not much more to say, it is a short flight with no in-flight services due to the length.
American Airlines
7.2
Good
11,271 reviews
Delta
7.9
Good
8,180 reviews

Boarding

8.1

Crew

8.5

Comfort

7.9

Overall

7.9

Entertainment

7.8

Food

7.2

Reviews

1 / 20
8.0
Excellent

Matthew,Oct 2025

GSP - ATL

This is always a full flight since it is the connecting route to primary destinations through Atlanta. That said, the crew handles the full load well. Not much more to say, it is a short flight with no in-flight services due to the length.

Related info for your journey

Find useful and relevant information for your journey from Columbia to Key Largo. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • What airport do you fly from for flights from Columbia to Key Largo?

    Columbia Metropolitan (CAE), located 6.5 mi from the city center, is the airport you fly out of when you book flights from Columbia to Key Largo. 4 airlines have flights from Metropolitan to Key Largo on a regular basis. Booking flights from Columbia Metropolitan to Key Largo should not be difficult; the airport handles an average of 0 outbound flights to Key Largo per day.

  • How long is the flight from Columbia to Key Largo?

    There are many flights that can get you from Columbia to Key Largo in 4h 54m. Fly via Delta to get the fastest option. The distance between Columbia and Key Largo is about 565 mi.

  • Can I find deals for flights from Columbia to Key Largo that include hotel bookings?

    Yes. In addition to deals on Columbia to Key Largo flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Columbia to Key Largo?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Columbia to Key Largo.

  • Can I find deals for business class flights from Columbia to Key Largo?

    Yes. Cheapflights offers flight deals from Columbia to Key Largo by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Columbia to Key Largo?

    Currently, March is the cheapest month in which you can book a flight from Columbia to Key Largo (average of $33). Flying from Columbia to Key Largo in April is currently the most expensive (average of $68). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

Browse thousands of different options on Cheapflights for your next trip

Toggle through the tabs below to find thousands of options on Cheapflights for your next trip.

Alternative routes for Columbia to Key Largo

See prices for flight routes from nearby airports that may be better suited for you.
Charlotte to Orlando flights
Charlotte to Miami flights
Charlotte to Fort Lauderdale flights
Charlotte to Tampa flights
Charlotte to West Palm Beach flights
Charleston to Miami flights
Charleston to Fort Lauderdale flights
Charlotte to Fort Myers flights
Greenville to Miami flights
Charlotte to Sarasota flights
Columbia to Orlando flights
Charlotte to Panama City flights
Charlotte to Jacksonville flights
Savannah to Miami flights
Myrtle Beach to Fort Lauderdale flights
Charlotte to Key West flights
Columbia to Miami flights
Myrtle Beach to Miami flights
Myrtle Beach to Tampa flights
Myrtle Beach to Orlando flights
Charlotte to Pensacola flights
Charleston to Orlando flights
Columbia to Fort Lauderdale flights
Charleston to Tampa flights
Charlotte to Melbourne flights
Charleston to Key West flights
Greenville to Tampa flights
Charleston to Sarasota flights
Charlotte to Valparaiso flights
Savannah to Tampa flights
Charleston to West Palm Beach flights
Greenville to West Palm Beach flights
Greenville to Fort Lauderdale flights
Columbia to Tampa flights
Columbia to West Palm Beach flights
Charleston to Pensacola flights
Charlotte to Daytona Beach flights
Savannah to Fort Myers flights
Greenville to Orlando flights
Augusta to Miami flights
Augusta to Orlando flights
Myrtle Beach to West Palm Beach flights
Greenville to Pensacola flights
Savannah to West Palm Beach flights
Savannah to Orlando flights
Greenville to Daytona Beach flights
Savannah to Fort Lauderdale flights
Greenville to Fort Myers flights
Myrtle Beach to Sarasota flights
Greenville to St Petersburg flights

Top 4 airlines flying from Columbia to Key Largo

Discover the top 4 airlines that operate flights from Columbia to Key Largo. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated February 12, 2026.
AirlineCheapestAverageFlexibilityOn-time
Spirit AirlinesCheapest$59Average$124FlexibilityNo cancel feeOn-time65%
Allegiant AirCheapest$67Average$84FlexibilityNo cancel feeOn-time88%
DeltaCheapest$163Average$428FlexibilityNo cancel feeOn-timeN/A
American AirlinesCheapest$244Average$467FlexibilityNo cancel feeOn-time71%

100% Free

Cheapflights is completely free to use, so you can start saving the moment you arrive.

Book with Flexibility

Our users can plan ahead with confidence and find flights with no change fees

Travel Smart

Millions of people come to us for their flight needs every year. We help make travel planning easy by providing useful insights and data-driven graphs that can inform your decisions.