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Italy

$435+ Cheap flights from St. Louis (STL) to Italy

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 9/15. Fares are subject to change and may not be available on all flights or dates of travel.
STL — NAP
Apr 21 — Apr 281
Tue 4/21
Tue 4/28
1 adult, Economy
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Cheap flight deals from St. Louis to Italy

Cheapest flights from St. Louis to Italy
Explore the most affordable flight options available from St. Louis to Italy. Find the lowest fares from popular airlines and budget airlines, with prices last updated on March 22, 2026.

This Cheapflightsfares deal was found by Cheapflights users on 3/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Cheapflightsfares is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 8/121:18 pm
STL
-
MXP
2 stops15h 57m
Lufthansa
Wed 8/266:00 am
MXP
-
STL
1 stop14h 25m
Lufthansa
Deal found 3/20$628
This Cheapflightsfares deal was found by Cheapflights users on 3/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Cheapflightsfares is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 8/121:18 pm
STL
-
LIN
2 stops12h 52m
Lufthansa
Wed 8/266:50 am
LIN
-
STL
1 stop13h 35m
Lufthansa
Deal found 3/20$632
This Cheapflightsfares deal was found by Cheapflights users on 3/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Cheapflightsfares is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 8/143:30 pm
STL
-
MXP
1 stop12h 05m
Lufthansa
Fri 8/286:20 am
MXP
-
STL
2 stops16h 18m
Lufthansa
Deal found 3/20$646
This oojo deal was found by Cheapflights users on 3/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure oojo is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 10/219:35 pm
STL
-
MXP
1 stop19h 00m
British Airways
Thu 11/52:20 pm
MXP
-
STL
1 stop13h 35m
British Airways
Deal found 3/22$649
This Cheapflightsfares deal was found by Cheapflights users on 3/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Cheapflightsfares is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 8/143:30 pm
STL
-
LIN
1 stop11h 25m
Lufthansa
Fri 8/281:40 pm
LIN
-
STL
2 stops16h 20m
Lufthansa
Deal found 3/20$650
This Iberia deal was found by Cheapflights users on 3/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Iberia is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 10/219:35 pm
STL
-
MXP
1 stop19h 00m
Multiple Airlines
Thu 11/52:20 pm
MXP
-
STL
1 stop13h 35m
Multiple Airlines
Deal found 3/21$654
This Cheapflightsfares deal was found by Cheapflights users on 3/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Cheapflightsfares is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 8/111:18 pm
STL
-
LIN
2 stops13h 42m
Lufthansa
Wed 8/261:40 pm
LIN
-
STL
2 stops16h 20m
Lufthansa
Deal found 3/22$654
This American Airlines deal was found by Cheapflights users on 3/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 10/212:47 pm
STL
-
MXP
2 stops15h 33m
American Airlines
Thu 11/52:20 pm
MXP
-
STL
1 stop13h 35m
American Airlines
Deal found 3/22$658
This United Airlines deal was found by Cheapflights users on 3/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 10/2112:10 pm
STL
-
MXP
1 stop15h 10m
United Airlines
Thu 11/53:05 pm
MXP
-
STL
1 stop14h 49m
United Airlines
Deal found 3/21$661
This United Airlines deal was found by Cheapflights users on 3/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 11/279:23 am
STL
-
MXP
2 stops15h 07m
United Airlines
Sat 12/129:45 am
MXP
-
STL
1 stop13h 55m
United Airlines
Deal found 3/21$662
This Air Canada deal was found by Cheapflights users on 3/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Air Canada is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 10/219:23 am
STL
-
MXP
2 stops17h 57m
Air Canada
Thu 11/511:35 am
MXP
-
STL
2 stops34h 55m
Air Canada
Deal found 3/22$665
This Air Canada deal was found by Cheapflights users on 3/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Air Canada is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 10/1912:10 pm
STL
-
LIN
2 stops17h 10m
Air Canada
Thu 11/52:50 pm
LIN
-
STL
2 stops31h 40m
Air Canada
Deal found 3/21$672

Find flight deals from St. Louis to Italy

Keep the following information in mind while searching for St. Louis to Italy flight deals. Data was last updated March 22, 2026.

Most accurate provider

FlightHub
3 stars

Most trusted provider

FlightHub
3 stars

Round-trip from

$628
(Cheapflightsfares)

One-way from

$435
(oojo)

Popular in

June

Cheapest in

February

Average price

$894
Provider with most accurate pricing for Lambert-St Louis-Rome (ROM) flight deals.
Search Deals
Provider most trusted by Cheapflights users for Lambert-St Louis-Rome (ROM) flights.
Search Deals
From Lambert-St Louis to Italy
Search Deals
One-way flight from Lambert-St Louis to Italy
Search Deals
Highest demand for flights based on searches. 30% potential increase in price ($399 potential increase over avg. RT price).
Search Deals
Cheapest flight prices on average. 7% potential price decrease ($62 potential savings vs. average RT price).
Search Deals
Average for round-trip flights in March 2026
Search Deals

Cheapflights Fare Finder

 
Customize your flight search to find flights from St. Louis to Italy that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated March 22, 2026.
Use the filters below to find and compare flights from St. Louis to Italy that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

Cheapest round-trip

St. LouisCatania

STL - CTA

STLCTA

Lambert-St Louis

Mon 4/20

6:55 pm-5:45 pm

2 stops15h 50m

Catania Fontanarossa

Wed 5/20

9:35 am-11:57 pm

2 stops21h 22m

$766

St. LouisFlorence

STL - FLR

STLFLR

Lambert-St Louis

Wed 4/15

10:00 am-12:50 pm

2 stops19h 50m

Florence Peretola

Wed 4/22

6:30 am-1:25 pm

1 stop13h 55m

$768

St. LouisBologna

STL - BLQ

STLBLQ

Lambert-St Louis

Thu 4/16

11:37 am-2:00 pm

2 stops19h 23m

Bologna Guglielmo Marconi

Thu 4/23

10:20 am-11:11 pm

2 stops19h 51m

$779

St. LouisMilan

STL - MXP

STLMXP

Lambert-St Louis

Sun 4/19

9:10 am-1:20 pm

1 stop21h 10m

Milan Malpensa

Sun 4/26

11:20 am-2:24 pm

2 stops34h 04m

$783

St. LouisNaples

STL - NAP

STLNAP

Lambert-St Louis

Mon 4/13

5:35 pm-3:20 pm

2 stops14h 45m

Naples

Thu 4/23

6:05 am-5:44 pm

2 stops18h 39m

$795
Quickest round-trip

St. LouisNaples

STL - NAP

STLNAP

Lambert-St Louis

Tue 4/7

11:37 am-7:00 am

1 stop12h 23m

Naples

Thu 4/16

6:00 am-3:25 pm

2 stops16h 25m

$801

St. LouisMilan

STL - MXP

STLMXP

Lambert-St Louis

Thu 4/30

7:45 am-1:20 pm

1 stop22h 35m

Milan Malpensa

Sun 5/3

3:20 pm-10:45 pm

1 stop14h 25m

$812

St. LouisNaples

STL - NAP

STLNAP

Lambert-St Louis

Tue 4/14

11:37 am-7:00 am

1 stop12h 23m

Naples

Tue 4/21

1:15 pm-1:25 pm

1 stop31h 10m

$813

St. LouisCatania

STL - CTA

STLCTA

Lambert-St Louis

Wed 5/6

1:05 pm-9:50 pm

2 stops25h 45m

Catania Fontanarossa

Wed 5/13

6:15 am-12:06 pm

3 stops36h 51m

$816

St. LouisFlorence

STL - FLR

STLFLR

Lambert-St Louis

Fri 4/17

9:10 am-12:50 pm

2 stops20h 40m

Florence Peretola

Wed 4/22

6:30 am-1:25 pm

1 stop13h 55m

$818

Flights are sorted by cheapest round-trip flights first.

Deals found on 3/20

Showing 1-10 of 60 resultsSorted by cheapest first
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6

Best time to book a flight from St. Louis to Italy

Have a flexible travel schedule? Discover the best time to fly to Italy from St. Louis with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from St. Louis to Italy

What is the cheapest month to book a flight from St. Louis to Italy?

Currently, March is the cheapest month in which you can book a flight from St. Louis to Italy (average of $441). Flying from St. Louis to Italy in July is currently the most expensive (average of $895). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

Reviews of airlines servicing Italy

Get insights into the airlines that provide service to Italy. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Italy. Reviews last updated March 22, 2026.
Get a feel of what it's like to fly with Delta,United Airlines, andAmerican Airlines from St. Louis to Italy by reading reviews from past customers. Users have also rated airlines in terms of entertainment options, comfort, food, crew/service, and boarding process.
Delta
7.9
Good
8,319 reviews

Entertainment

7.8

Crew

8.5

Overall

7.9

Boarding

8.1

Comfort

7.9

Food

7.2

Reviews

1 / 20
6.0
Good

Jim,Nov 2025

AVL - ATL

The exit row seats without a seat in front are great for leg room but don’t have a fold out entertainment console so you’re forced to use the screen several feet in front of you (there is, at least, a remote). Best to bring a tablet loaded with entertainment or a book.
Delta
7.9
Good
8,319 reviews
Delta
7.9
Good
8,319 reviews

Entertainment

7.8

Crew

8.5

Overall

7.9

Boarding

8.1

Comfort

7.9

Food

7.2

Reviews

1 / 20
6.0
Good

Jim,Nov 2025

AVL - ATL

The exit row seats without a seat in front are great for leg room but don’t have a fold out entertainment console so you’re forced to use the screen several feet in front of you (there is, at least, a remote). Best to bring a tablet loaded with entertainment or a book.
United Airlines
7.4
Good
9,460 reviews
Delta
7.9
Good
8,319 reviews

Entertainment

7.8

Crew

8.5

Overall

7.9

Boarding

8.1

Comfort

7.9

Food

7.2

Reviews

1 / 20
6.0
Good

Jim,Nov 2025

AVL - ATL

The exit row seats without a seat in front are great for leg room but don’t have a fold out entertainment console so you’re forced to use the screen several feet in front of you (there is, at least, a remote). Best to bring a tablet loaded with entertainment or a book.
American Airlines
7.1
Good
11,489 reviews
Delta
7.9
Good
8,319 reviews

Entertainment

7.8

Crew

8.5

Overall

7.9

Boarding

8.1

Comfort

7.9

Food

7.2

Reviews

1 / 20
6.0
Good

Jim,Nov 2025

AVL - ATL

The exit row seats without a seat in front are great for leg room but don’t have a fold out entertainment console so you’re forced to use the screen several feet in front of you (there is, at least, a remote). Best to bring a tablet loaded with entertainment or a book.
Air Canada
7.1
Good
10,834 reviews
Delta
7.9
Good
8,319 reviews

Entertainment

7.8

Crew

8.5

Overall

7.9

Boarding

8.1

Comfort

7.9

Food

7.2

Reviews

1 / 20
6.0
Good

Jim,Nov 2025

AVL - ATL

The exit row seats without a seat in front are great for leg room but don’t have a fold out entertainment console so you’re forced to use the screen several feet in front of you (there is, at least, a remote). Best to bring a tablet loaded with entertainment or a book.
Lufthansa
6.8
Okay
7,862 reviews
Delta
7.9
Good
8,319 reviews

Entertainment

7.8

Crew

8.5

Overall

7.9

Boarding

8.1

Comfort

7.9

Food

7.2

Reviews

1 / 20
6.0
Good

Jim,Nov 2025

AVL - ATL

The exit row seats without a seat in front are great for leg room but don’t have a fold out entertainment console so you’re forced to use the screen several feet in front of you (there is, at least, a remote). Best to bring a tablet loaded with entertainment or a book.

Related info for your journey

Find useful and relevant information for your journey from St. Louis to Italy. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • What airport do you fly from for flights from St. Louis to Italy?

    If you book a flight to Italy from St. Louis, you will be flying from Lambert-St Louis, which is the city’s only airport. Lambert-St Louis (STL) is located 12.7 mi from the center of St. Louis.

  • How long is the flight from St. Louis to Italy?

    Lufthansa, United Airlines, and KLM can get you from St. Louis to Italy in just under 14h 45m. Your travel time can differ by up to 5h 05m. St. Louis and Italy are separated by a distance of 5172 mi. This flight may include one or multiple stops.

  • What are the cheapest airlines to fly from St. Louis to Italy one-way?

    The cheapest airlines for a one-way flight from St. Louis to Italy are American Airlines ($98), Delta ($98), and Southwest ($105).

  • What are the most popular routes from St. Louis to Italy?

    Most travelers choose Lambert-St Louis - Rome Fiumicino, Lambert-St Louis - Milan Malpensa or Lambert-St Louis - Venice Marco Polo when deciding on the best route from St. Louis to Italy.

  • Can I find deals for flights from St. Louis to Italy that include hotel bookings?

    Yes. In addition to deals on St. Louis to Italy flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from St. Louis to Italy?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from St. Louis to Italy.

  • Can I find deals for business class flights from St. Louis to Italy?

    Yes. Cheapflights offers flight deals from St. Louis to Italy by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from St. Louis to Italy?

    Currently, March is the cheapest month in which you can book a flight from St. Louis to Italy (average of $441). Flying from St. Louis to Italy in July is currently the most expensive (average of $895). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

Browse thousands of different options on Cheapflights for your next trip

Toggle through the tabs below to find thousands of options on Cheapflights for your next trip.

Top 7 airlines flying from St. Louis to Italy

Discover the top 7 airlines that operate flights from St. Louis to Italy. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated March 22, 2026.
AirlineCheapestAverageFlexibilityOn-time
British AirwaysCheapest$472Average$1,018FlexibilityNo cancel feeOn-time70%
United AirlinesCheapest$472Average$977FlexibilityNo cancel feeOn-time69%
LufthansaCheapest$493Average$1,052FlexibilityNo cancel feeOn-time76%
KLMCheapest$506Average$950FlexibilityNo cancel feeOn-time75%
Air CanadaCheapest$552Average$1,052FlexibilityNo cancel feeOn-time67%
DeltaCheapest$555Average$1,044FlexibilityNo cancel feeOn-timeN/A
American AirlinesCheapest$559Average$1,031FlexibilityNo cancel feeOn-time71%

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