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$276+ Cheap flights from St. Louis (STL) to Italy

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 1/18. Fares are subject to change and may not be available on all flights or dates of travel.
STL — NAP
Dec 11 — Dec 181
Thu 12/11
Thu 12/18
1 adult, Economy
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Cheap flight deals from St. Louis to Italy

Keep the following information in mind while searching for St. Louis to Italy flight deals. Data was last updated November 11, 2025.

Most accurate provider

eDreams
3 stars

Most trusted provider

eDreams
3 stars

Round-trip from

$475
(Mytrip)

One-way from

$276
(Kiwi.com)

Popular in

June

Cheapest in

February

Average price

$716
Provider with most accurate pricing for Lambert-St Louis-Rome (ROM) flight deals.
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Provider most trusted by Cheapflights users for Lambert-St Louis-Rome (ROM) flights.
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From Lambert-St Louis to Italy
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One-way flight from Lambert-St Louis to Italy
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Highest demand for flights based on searches. 26% potential increase in price ($353 potential increase over avg. RT price).
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Cheapest flight prices on average. 5% potential price decrease ($54 potential savings vs. average RT price).
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Average for round-trip flights in November 2025
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Find flight deals from St. Louis to Italy

Cheapest flights from St. Louis to Italy
Explore the most affordable flight options available from St. Louis to Italy. Find the lowest fares from popular airlines and budget airlines, with prices last updated on November 11, 2025.

This Mytrip deal was found by Cheapflights users on 11/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Mytrip is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 11/174:05 pmSTL - MXP
2 stops14h 40mMultiple Airlines
Wed 12/36:55 amMXP - STL
1 stop14h 00mMultiple Airlines
Deal found 11/9$475
This United Airlines deal was found by Cheapflights users on 11/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 12/71:00 pmSTL - FCO
1 stop11h 45mUnited Airlines
Sun 12/141:10 pmFCO - STL
2 stops33h 30mUnited Airlines
Deal found 11/9$483
This Mytrip deal was found by Cheapflights users on 11/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Mytrip is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 11/174:05 pmSTL - LIN
2 stops15h 00mMultiple Airlines
Wed 12/36:10 amLIN - STL
1 stop14h 45mMultiple Airlines
Deal found 11/9$489
This Finnair deal was found by Cheapflights users on 11/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Finnair is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 12/307:00 amSTL - FCO
1 stop20h 45mMultiple Airlines
Wed 1/146:40 pmFCO - STL
2 stops31h 49mMultiple Airlines
Deal found 11/11$505
This KLM deal was found by Cheapflights users on 11/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure KLM is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 12/307:00 amSTL - FCO
1 stop20h 30mKLM
Wed 1/1412:40 pmFCO - STL
1 stop27h 13mKLM
Deal found 11/11$511
This United Airlines deal was found by Cheapflights users on 11/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 12/311:50 amSTL - MXP
1 stop12h 40mUnited Airlines
Sun 12/71:05 pmMXP - STL
2 stops33h 35mUnited Airlines
Deal found 11/10$520
This Air Canada deal was found by Cheapflights users on 11/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Air Canada is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 12/34:05 pmSTL - MXP
2 stops34h 45mAir Canada
Sun 12/71:05 pmMXP - STL
2 stops33h 24mAir Canada
Deal found 11/9$522
This Air Canada deal was found by Cheapflights users on 11/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Air Canada is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 11/284:05 pmSTL - MXP
2 stops34h 50mAir Canada
Sun 12/71:05 pmMXP - STL
2 stops57h 24mAir Canada
Deal found 11/10$530
This United Airlines deal was found by Cheapflights users on 11/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 11/295:24 pmSTL - MXP
1 stop12h 41mUnited Airlines
Sun 12/71:05 pmMXP - STL
2 stops27h 55mUnited Airlines
Deal found 11/10$531
This United Airlines deal was found by Cheapflights users on 11/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 11/285:24 pmSTL - MXP
1 stop12h 41mUnited Airlines
Sat 12/69:45 amMXP - STL
2 stops20h 00mUnited Airlines
Deal found 11/10$536
This United Airlines deal was found by Cheapflights users on 11/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 12/35:27 pmSTL - LIN
2 stops16h 28mUnited Airlines
Sun 12/76:15 amLIN - STL
2 stops16h 25mUnited Airlines
Deal found 11/9$538
This United Airlines deal was found by Cheapflights users on 11/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 11/103:14 pmSTL - MXP
1 stop14h 51mUnited Airlines
Mon 11/171:05 pmMXP - STL
2 stops33h 42mUnited Airlines
Deal found 11/9$539

Cheapflights Fare Finder

 
Customize your flight search to find flights from St. Louis to Italy that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated November 11, 2025.
Use the filters below to find and compare flights from St. Louis to Italy that are best for you.

Fly from

St. Louis

Fly to

Italy

Route

Depart

Return

Price

St. LouisVenice

STL - VCE

STLVCE

Lambert-St Louis

Sun 1/18

4:05 pm-2:25 pm

2 stops15h 20m

Venice Marco Polo

Sun 1/25

6:45 am-1:55 pm

1 stop14h 10m

$475

St. LouisRome

STL - FCO

STLFCO

Lambert-St Louis

Sun 12/7

1:00 pm-7:45 am

1 stop11h 45m

Rome Fiumicino

Sun 12/14

1:10 pm-3:40 pm

2 stops33h 30m

$483

St. LouisMilan

STL - MXP

STLMXP

Lambert-St Louis

Mon 11/17

10:00 am-1:05 pm

1 stop20h 05m

Milan Malpensa

Wed 12/3

6:55 am-1:55 pm

1 stop14h 00m

$485

St. LouisMilan

STL - LIN

STLLIN

Lambert-St Louis

Mon 11/17

4:05 pm-2:05 pm

2 stops15h 00m

Milan Linate

Wed 12/3

6:10 am-1:55 pm

1 stop14h 45m

$489

St. LouisMilan

STL - MXP

STLMXP

Lambert-St Louis

Mon 2/9

1:15 pm-8:45 pm

2 stops24h 30m

Milan Malpensa

Tue 2/17

6:55 am-12:05 am

2 stops24h 10m

$492

St. LouisVenice

STL - VCE

STLVCE

Lambert-St Louis

Sun 1/18

3:50 pm-6:05 pm

1 stop19h 15m

Venice Marco Polo

Sun 1/25

6:45 am-1:55 pm

1 stop14h 10m

$493

St. LouisMilan

STL - MXP

STLMXP

Lambert-St Louis

Mon 2/9

6:00 am-9:05 am

1 stop20h 05m

Milan Malpensa

Tue 2/17

11:05 am-9:08 am

1 stop29h 03m

$495

St. LouisRome

STL - FCO

STLFCO

Lambert-St Louis

Wed 1/7

6:40 pm-6:15 pm

2 stops16h 35m

Rome Fiumicino

Thu 1/15

12:50 pm-5:43 pm

2 stops35h 53m

$497

St. LouisMilan

STL - MXP

STLMXP

Lambert-St Louis

Mon 2/9

6:35 am-11:40 am

2 stops22h 05m

Milan Malpensa

Tue 2/17

11:05 am-9:08 am

1 stop29h 03m

$499

St. LouisRome

STL - FCO

STLFCO

Lambert-St Louis

Tue 12/30

1:59 pm-9:00 am

1 stop12h 01m

Rome Fiumicino

Wed 1/14

6:40 pm-10:59 pm

2 stops35h 19m

$505

Flights are sorted by cheapest round-trip flights first.

Deals found on 11/9

Showing 1-10 of 51 results
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Best time to book a flight from St. Louis to Italy

Have a flexible travel schedule? Discover the best time to fly to Italy from St. Louis with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from St. Louis to Italy

What is the cheapest month to book a flight from St. Louis to Italy?

Currently, November is the cheapest month in which you can book a flight from St. Louis to Italy (average of $470). Flying from St. Louis to Italy in June is currently the most expensive (average of $1,009). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

What is the cheapest time of day to fly from STL to IT?

Find hourly flight availability from St. Louis to Italy. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated November 11, 2025.

One of the essential ways to save on airfare from St. Louis to Italy is to remain as flexible as possible. Flights that are at noon tend to be the most expensive. A flight in the evening could potentially save you up to 28% on airfare.

Reviews of airlines servicing Italy

Get insights into the airlines that provide service to Italy. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Italy. Reviews last updated November 11, 2025.
Get a feel of what it's like to fly with Delta, United Airlines, and American Airlines from St. Louis to Italy by reading reviews from past customers. Users have also rated airlines in terms of entertainment options, comfort, food, crew/service, and boarding process.
Delta
7.9
Good
8,008 reviews

Crew

8.5

Boarding

8.1

Comfort

7.9

Food

7.3

Overall

7.9

Entertainment

7.9

Reviews

1 / 20
6.0
Good

Jim,Nov 2025

AVL - ATL

The exit row seats without a seat in front are great for leg room but don’t have a fold out entertainment console so you’re forced to use the screen several feet in front of you (there is, at least, a remote). Best to bring a tablet loaded with entertainment or a book.
Delta
7.9
Good
8,008 reviews
Delta
7.9
Good
8,008 reviews

Crew

8.5

Boarding

8.1

Comfort

7.9

Food

7.3

Overall

7.9

Entertainment

7.9

Reviews

1 / 20
6.0
Good

Jim,Nov 2025

AVL - ATL

The exit row seats without a seat in front are great for leg room but don’t have a fold out entertainment console so you’re forced to use the screen several feet in front of you (there is, at least, a remote). Best to bring a tablet loaded with entertainment or a book.
United Airlines
7.4
Good
9,015 reviews
Delta
7.9
Good
8,008 reviews

Crew

8.5

Boarding

8.1

Comfort

7.9

Food

7.3

Overall

7.9

Entertainment

7.9

Reviews

1 / 20
6.0
Good

Jim,Nov 2025

AVL - ATL

The exit row seats without a seat in front are great for leg room but don’t have a fold out entertainment console so you’re forced to use the screen several feet in front of you (there is, at least, a remote). Best to bring a tablet loaded with entertainment or a book.
American Airlines
7.2
Good
11,049 reviews
Delta
7.9
Good
8,008 reviews

Crew

8.5

Boarding

8.1

Comfort

7.9

Food

7.3

Overall

7.9

Entertainment

7.9

Reviews

1 / 20
6.0
Good

Jim,Nov 2025

AVL - ATL

The exit row seats without a seat in front are great for leg room but don’t have a fold out entertainment console so you’re forced to use the screen several feet in front of you (there is, at least, a remote). Best to bring a tablet loaded with entertainment or a book.
Air Canada
7.1
Good
10,442 reviews
Delta
7.9
Good
8,008 reviews

Crew

8.5

Boarding

8.1

Comfort

7.9

Food

7.3

Overall

7.9

Entertainment

7.9

Reviews

1 / 20
6.0
Good

Jim,Nov 2025

AVL - ATL

The exit row seats without a seat in front are great for leg room but don’t have a fold out entertainment console so you’re forced to use the screen several feet in front of you (there is, at least, a remote). Best to bring a tablet loaded with entertainment or a book.
Lufthansa
6.8
Okay
7,565 reviews
Delta
7.9
Good
8,008 reviews

Crew

8.5

Boarding

8.1

Comfort

7.9

Food

7.3

Overall

7.9

Entertainment

7.9

Reviews

1 / 20
6.0
Good

Jim,Nov 2025

AVL - ATL

The exit row seats without a seat in front are great for leg room but don’t have a fold out entertainment console so you’re forced to use the screen several feet in front of you (there is, at least, a remote). Best to bring a tablet loaded with entertainment or a book.

Related info for your journey

Find useful and relevant information for your journey from St. Louis to Italy. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • What airport do you fly from for flights from St. Louis to Italy?

    If you book a flight to Italy from St. Louis, you will be flying from Lambert-St Louis, which is the city’s only airport. Lambert-St Louis (STL) is located 12.7 mi from the center of St. Louis.

  • How long is the flight from St. Louis to Italy?

    United Airlines, Lufthansa, and KLM can get you from St. Louis to Italy in just under 11h 45m. Your travel time can differ by up to 12h 45m. St. Louis and Italy are separated by a distance of 5050 mi. This flight may include one or multiple stops.

  • What are the cheapest airlines to fly from St. Louis to Italy one-way?

    The cheapest airlines for a one-way flight from St. Louis to Italy are KLM ($384), Air Canada ($399), and British Airways ($416).

  • What are the most popular routes from St. Louis to Italy?

    Most travelers choose Lambert-St Louis - Rome Fiumicino, Lambert-St Louis - Milan Malpensa or Lambert-St Louis - Venice Marco Polo when deciding on the best route from St. Louis to Italy.

  • Can I find deals for flights from St. Louis to Italy that include hotel bookings?

    Yes. In addition to deals on St. Louis to Italy flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from St. Louis to Italy?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from St. Louis to Italy.

  • Can I find deals for business class flights from St. Louis to Italy?

    Yes. Cheapflights offers flight deals from St. Louis to Italy by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from St. Louis to Italy?

    Currently, November is the cheapest month in which you can book a flight from St. Louis to Italy (average of $470). Flying from St. Louis to Italy in June is currently the most expensive (average of $1,009). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

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Alternative routes for St. Louis to Italy

See prices for flight routes from nearby airports that may be better suited for you.
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Top 8 airlines flying from St. Louis to Italy

Discover the top 8 airlines that operate flights from St. Louis to Italy. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated November 11, 2025.
AirlineCheapestAverageFlexibilityOn-time
United AirlinesCheapest$485Average$1,115FlexibilityNo cancel feeOn-time69%
LufthansaCheapest$493Average$1,272FlexibilityNo cancel feeOn-time76%
IberiaCheapest$536Average$1,129FlexibilityNo cancel feeOn-time77%
British AirwaysCheapest$545Average$973FlexibilityNo cancel feeOn-time70%
KLMCheapest$566Average$1,009FlexibilityNo cancel feeOn-time75%
DeltaCheapest$587Average$1,150FlexibilityNo cancel feeOn-timeN/A
American AirlinesCheapest$619Average$1,064FlexibilityNo cancel feeOn-time71%
Air CanadaCheapest$705Average$1,202FlexibilityNo cancel feeOn-time67%

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