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$292+ Cheap flights from St. Louis (STL) to Italy

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 1/18. Fares are subject to change and may not be available on all flights or dates of travel.
STL — NAP
Dec 18 — Dec 251
Thu 12/18
Thu 12/25
1 adult, Economy
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Cheap flight deals from St. Louis to Italy

Keep the following information in mind while searching for St. Louis to Italy flight deals. Data was last updated November 18, 2025.

Most accurate provider

eDreams
3 stars

Most trusted provider

eDreams
3 stars

Round-trip from

$473
(Booking.com)

One-way from

$292
(Kiwi.com)

Popular in

June

Cheapest in

November

Average price

$709
Provider with most accurate pricing for Lambert-St Louis-Rome (ROM) flight deals.
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Provider most trusted by Cheapflights users for Lambert-St Louis-Rome (ROM) flights.
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From Lambert-St Louis to Italy
Search Deals
One-way flight from Lambert-St Louis to Italy
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Highest demand for flights based on searches. 26% potential increase in price ($353 potential increase over avg. RT price).
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Cheapest flight prices on average. 5% potential price decrease ($55 potential savings vs. average RT price).
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Average for round-trip flights in November 2025
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Find flight deals from St. Louis to Italy

Cheapest flights from St. Louis to Italy
Explore the most affordable flight options available from St. Louis to Italy. Find the lowest fares from popular airlines and budget airlines, with prices last updated on November 18, 2025.

This lol.travel deal was found by Cheapflights users on 11/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure lol.travel is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 11/246:43 pmSTL - MXP
2 stops14h 57mLufthansa
Tue 12/96:55 amMXP - STL
2 stops23h 47mLufthansa
Deal found 11/17$472
This Booking.com deal was found by Cheapflights users on 11/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Booking.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 11/2412:31 pmSTL - MXP
2 stops14h 24mAir Canada
Tue 12/91:05 pmMXP - STL
3 stops32h 20mAir Canada
Deal found 11/17$482
This Finnair deal was found by Cheapflights users on 11/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Finnair is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 11/248:13 amSTL - MXP
2 stops16h 52mMultiple Airlines
Tue 12/910:25 amMXP - STL
1 stop16h 55mMultiple Airlines
Deal found 11/17$489
This United Airlines deal was found by Cheapflights users on 11/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 12/306:35 pmSTL - FCO
2 stops16h 40mUnited Airlines
Wed 1/1411:15 amFCO - STL
2 stops34h 15mUnited Airlines
Deal found 11/17$490
This Air Canada deal was found by Cheapflights users on 11/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Air Canada is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 12/26:42 pmSTL - MXP
2 stops32h 13mAir Canada
Wed 12/1011:35 amMXP - STL
2 stops34h 54mAir Canada
Deal found 11/17$494
This Finnair deal was found by Cheapflights users on 11/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Finnair is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 12/36:52 amSTL - MXP
2 stops18h 13mMultiple Airlines
Wed 12/1010:25 amMXP - STL
2 stops15h 18mMultiple Airlines
Deal found 11/17$502
This Booking.com deal was found by Cheapflights users on 11/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Booking.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 11/2610:00 amSTL - MXP
2 stops16h 55mMultiple Airlines
Tue 12/22:40 pmMXP - STL
1 stop30h 15mMultiple Airlines
Deal found 11/17$503
This KAYAK deal was found by Cheapflights users on 11/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure KAYAK is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 12/16:43 pmSTL - MXP
2 stops19h 02mLufthansa
Wed 12/106:55 amMXP - STL
2 stops17h 08mLufthansa
Deal found 11/17$504
This Cheapflightsfares deal was found by Cheapflights users on 11/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Cheapflightsfares is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 12/306:35 pmSTL - FCO
2 stops16h 40mLufthansa
Wed 1/1410:30 amFCO - STL
1 stop20h 29mLufthansa
Deal found 11/17$505
This KLM deal was found by Cheapflights users on 11/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure KLM is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 12/307:00 amSTL - FCO
1 stop20h 30mKLM
Wed 1/1412:45 pmFCO - STL
2 stops17h 54mKLM
Deal found 11/18$507
This KLM deal was found by Cheapflights users on 11/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure KLM is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 12/24:32 pmSTL - MXP
1 stop34h 13mKLM
Wed 12/1012:00 pmMXP - STL
1 stop35h 35mKLM
Deal found 11/17$508
This Expedia deal was found by Cheapflights users on 11/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Expedia is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 11/266:30 amSTL - MXP
3 stops20h 25mAir Canada
Tue 12/21:05 pmMXP - STL
2 stops32h 20mAir Canada
Deal found 11/17$509

Cheapflights Fare Finder

 
Customize your flight search to find flights from St. Louis to Italy that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated November 18, 2025.
Use the filters below to find and compare flights from St. Louis to Italy that are best for you.

Fly from

St. Louis

Fly to

Italy

Route

Depart

Return

Price

St. LouisMilan

STL - MXP

STLMXP

Lambert-St Louis

Fri 1/9

4:49 pm-9:55 am

2 stops34h 06m

Milan Malpensa

Fri 1/23

1:05 pm-12:29 pm

2 stops30h 24m

$473

St. LouisMilan

STL - MXP

STLMXP

Lambert-St Louis

Fri 1/9

6:40 pm-9:55 am

2 stops32h 15m

Milan Malpensa

Fri 1/23

6:55 am-1:55 pm

1 stop14h 00m

$482

St. LouisBologna

STL - BLQ

STLBLQ

Lambert-St Louis

Fri 1/9

3:50 pm-1:50 pm

1 stop15h 00m

Bologna Guglielmo Marconi

Wed 1/14

6:30 am-11:59 pm

2 stops24h 29m

$483

St. LouisMilan

STL - MXP

STLMXP

Lambert-St Louis

Wed 11/26

6:30 am-9:55 am

2 stops20h 25m

Milan Malpensa

Tue 12/2

1:05 pm-2:25 pm

2 stops32h 20m

$489

St. LouisRome

STL - FCO

STLFCO

Lambert-St Louis

Tue 12/30

6:35 pm-6:15 pm

2 stops16h 40m

Rome Fiumicino

Wed 1/14

11:15 am-2:30 pm

2 stops34h 15m

$490

St. LouisRome

STL - FCO

STLFCO

Lambert-St Louis

Thu 1/15

6:00 pm-9:25 am

2 stops32h 25m

Rome Fiumicino

Tue 1/20

1:10 pm-5:18 pm

2 stops35h 08m

$490

St. LouisBologna

STL - BLQ

STLBLQ

Lambert-St Louis

Fri 1/9

2:54 pm-5:35 pm

2 stops19h 41m

Bologna Guglielmo Marconi

Wed 1/14

7:20 am-6:14 pm

2 stops17h 54m

$491

St. LouisRome

STL - FCO

STLFCO

Lambert-St Louis

Wed 1/14

9:57 am-1:25 pm

2 stops20h 28m

Rome Fiumicino

Wed 1/21

11:15 am-7:27 pm

2 stops39h 12m

$491

St. LouisMilan

STL - LIN

STLLIN

Lambert-St Louis

Fri 1/9

3:50 pm-10:05 am

1 stop11h 15m

Milan Linate

Fri 1/23

2:55 pm-3:29 pm

2 stops31h 34m

$493

St. LouisRome

STL - FCO

STLFCO

Lambert-St Louis

Sun 2/1

6:40 pm-6:15 pm

2 stops16h 35m

Rome Fiumicino

Fri 2/13

7:05 am-12:05 am

2 stops24h 00m

$494

Flights are sorted by cheapest round-trip flights first.

Deals found on 11/17

Showing 1-10 of 60 results
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Best time to book a flight from St. Louis to Italy

Have a flexible travel schedule? Discover the best time to fly to Italy from St. Louis with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from St. Louis to Italy

What is the cheapest month to book a flight from St. Louis to Italy?

Currently, November is the cheapest month in which you can book a flight from St. Louis to Italy (average of $470). Flying from St. Louis to Italy in June is currently the most expensive (average of $1,009). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

What is the cheapest time of day to fly from STL to IT?

Find hourly flight availability from St. Louis to Italy. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated November 18, 2025.

One of the essential ways to save on airfare from St. Louis to Italy is to remain as flexible as possible. Flights that are at noon tend to be the most expensive. A flight in the evening could potentially save you up to 28% on airfare.

Reviews of airlines servicing Italy

Get insights into the airlines that provide service to Italy. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Italy. Reviews last updated November 18, 2025.
Get a feel of what it's like to fly with Delta, United Airlines, and American Airlines from St. Louis to Italy by reading reviews from past customers. Users have also rated airlines in terms of entertainment options, comfort, food, crew/service, and boarding process.
Delta
7.9
Good
8,007 reviews

Comfort

7.9

Entertainment

7.9

Overall

7.9

Boarding

8.1

Food

7.3

Crew

8.5

Reviews

1 / 20
6.0
Good

Jim,Nov 2025

AVL - ATL

The exit row seats without a seat in front are great for leg room but don’t have a fold out entertainment console so you’re forced to use the screen several feet in front of you (there is, at least, a remote). Best to bring a tablet loaded with entertainment or a book.
Delta
7.9
Good
8,007 reviews
Delta
7.9
Good
8,007 reviews

Comfort

7.9

Entertainment

7.9

Overall

7.9

Boarding

8.1

Food

7.3

Crew

8.5

Reviews

1 / 20
6.0
Good

Jim,Nov 2025

AVL - ATL

The exit row seats without a seat in front are great for leg room but don’t have a fold out entertainment console so you’re forced to use the screen several feet in front of you (there is, at least, a remote). Best to bring a tablet loaded with entertainment or a book.
United Airlines
7.4
Good
9,015 reviews
Delta
7.9
Good
8,007 reviews

Comfort

7.9

Entertainment

7.9

Overall

7.9

Boarding

8.1

Food

7.3

Crew

8.5

Reviews

1 / 20
6.0
Good

Jim,Nov 2025

AVL - ATL

The exit row seats without a seat in front are great for leg room but don’t have a fold out entertainment console so you’re forced to use the screen several feet in front of you (there is, at least, a remote). Best to bring a tablet loaded with entertainment or a book.
American Airlines
7.2
Good
11,047 reviews
Delta
7.9
Good
8,007 reviews

Comfort

7.9

Entertainment

7.9

Overall

7.9

Boarding

8.1

Food

7.3

Crew

8.5

Reviews

1 / 20
6.0
Good

Jim,Nov 2025

AVL - ATL

The exit row seats without a seat in front are great for leg room but don’t have a fold out entertainment console so you’re forced to use the screen several feet in front of you (there is, at least, a remote). Best to bring a tablet loaded with entertainment or a book.
Air Canada
7.1
Good
10,459 reviews
Delta
7.9
Good
8,007 reviews

Comfort

7.9

Entertainment

7.9

Overall

7.9

Boarding

8.1

Food

7.3

Crew

8.5

Reviews

1 / 20
6.0
Good

Jim,Nov 2025

AVL - ATL

The exit row seats without a seat in front are great for leg room but don’t have a fold out entertainment console so you’re forced to use the screen several feet in front of you (there is, at least, a remote). Best to bring a tablet loaded with entertainment or a book.
Lufthansa
6.8
Okay
7,576 reviews
Delta
7.9
Good
8,007 reviews

Comfort

7.9

Entertainment

7.9

Overall

7.9

Boarding

8.1

Food

7.3

Crew

8.5

Reviews

1 / 20
6.0
Good

Jim,Nov 2025

AVL - ATL

The exit row seats without a seat in front are great for leg room but don’t have a fold out entertainment console so you’re forced to use the screen several feet in front of you (there is, at least, a remote). Best to bring a tablet loaded with entertainment or a book.

Related info for your journey

Find useful and relevant information for your journey from St. Louis to Italy. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • What airport do you fly from for flights from St. Louis to Italy?

    If you book a flight to Italy from St. Louis, you will be flying from Lambert-St Louis, which is the city’s only airport. Lambert-St Louis (STL) is located 12.7 mi from the center of St. Louis.

  • How long is the flight from St. Louis to Italy?

    Air Canada, Lufthansa, and United Airlines can get you from St. Louis to Italy in just under 15h. Your travel time can differ by up to 19h 06m. St. Louis and Italy are separated by a distance of 4898 mi. This flight may include one or multiple stops.

  • What are the cheapest airlines to fly from St. Louis to Italy one-way?

    The cheapest airlines for a one-way flight from St. Louis to Italy are KLM ($322), United Airlines ($322), and Delta ($322).

  • What are the most popular routes from St. Louis to Italy?

    Most travelers choose Lambert-St Louis - Rome Fiumicino, Lambert-St Louis - Milan Malpensa or Lambert-St Louis - Venice Marco Polo when deciding on the best route from St. Louis to Italy.

  • Can I find deals for flights from St. Louis to Italy that include hotel bookings?

    Yes. In addition to deals on St. Louis to Italy flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from St. Louis to Italy?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from St. Louis to Italy.

  • Can I find deals for business class flights from St. Louis to Italy?

    Yes. Cheapflights offers flight deals from St. Louis to Italy by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from St. Louis to Italy?

    Currently, November is the cheapest month in which you can book a flight from St. Louis to Italy (average of $470). Flying from St. Louis to Italy in June is currently the most expensive (average of $1,009). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

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Alternative routes for St. Louis to Italy

See prices for flight routes from nearby airports that may be better suited for you.
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Top 8 airlines flying from St. Louis to Italy

Discover the top 8 airlines that operate flights from St. Louis to Italy. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated November 18, 2025.
AirlineCheapestAverageFlexibilityOn-time
United AirlinesCheapest$485Average$1,115FlexibilityNo cancel feeOn-time69%
LufthansaCheapest$493Average$1,272FlexibilityNo cancel feeOn-time76%
IberiaCheapest$536Average$1,129FlexibilityNo cancel feeOn-time77%
British AirwaysCheapest$545Average$973FlexibilityNo cancel feeOn-time70%
KLMCheapest$566Average$1,009FlexibilityNo cancel feeOn-time75%
DeltaCheapest$587Average$1,150FlexibilityNo cancel feeOn-timeN/A
American AirlinesCheapest$619Average$1,064FlexibilityNo cancel feeOn-time71%
Air CanadaCheapest$705Average$1,202FlexibilityNo cancel feeOn-time67%

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