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Italy

$457+ Cheap flights from Knoxville (TYS) to Italy

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 6/6. Fares are subject to change and may not be available on all flights or dates of travel.
TYS — NAP
Feb 26 — Mar 51
Thu 2/26
Thu 3/5
1 adult, Economy
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Cheap flight deals from Knoxville to Italy

Cheapest flights from Knoxville to Italy
Explore the most affordable flight options available from Knoxville to Italy. Find the lowest fares from popular airlines and budget airlines, with prices last updated on January 27, 2026.

This United Airlines deal was found by Cheapflights users on 1/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 2/2410:53 am
TYS
-
FCO
1 stop14h 52m
United Airlines
Tue 3/31:05 pm
FCO
-
TYS
2 stops37h 32m
United Airlines
Deal found 1/27$493
This Booking.com deal was found by Cheapflights users on 1/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Booking.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 8/62:00 pm
TYS
-
MXP
3 stops38h 20m
Air Canada
Fri 8/2112:20 pm
MXP
-
TYS
2 stops32h 22m
Air Canada
Deal found 1/25$494
This United Airlines deal was found by Cheapflights users on 1/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 8/67:00 am
TYS
-
MXP
1 stop24h 20m
United Airlines
Fri 8/2112:20 pm
MXP
-
TYS
2 stops30h 58m
United Airlines
Deal found 1/25$495
This United Airlines deal was found by Cheapflights users on 1/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 3/111:53 pm
TYS
-
FLR
2 stops16h 07m
United Airlines
Wed 3/186:30 am
FLR
-
TYS
2 stops17h 59m
United Airlines
Deal found 1/25$502
This Travelocity deal was found by Cheapflights users on 1/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Travelocity is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 2/247:25 pm
TYS
-
FCO
2 stops33h 40m
Air Canada
Tue 3/31:05 pm
FCO
-
TYS
2 stops36h 24m
Air Canada
Deal found 1/27$502
This KAYAK deal was found by Cheapflights users on 1/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure KAYAK is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 8/66:21 am
TYS
-
MXP
1 stop21h 44m
British Airways
Fri 8/212:20 pm
MXP
-
TYS
1 stop13h 24m
British Airways
Deal found 1/25$503
This United Airlines deal was found by Cheapflights users on 1/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 3/129:40 am
TYS
-
VCE
2 stops20h 35m
United Airlines
Thu 3/191:50 pm
VCE
-
TYS
2 stops34h 39m
United Airlines
Deal found 1/26$505
This United Airlines deal was found by Cheapflights users on 1/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 3/202:21 pm
TYS
-
LIN
2 stops16h 34m
United Airlines
Wed 3/252:55 pm
LIN
-
TYS
2 stops24h 54m
United Airlines
Deal found 1/26$507
This oojo deal was found by Cheapflights users on 1/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure oojo is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 3/96:10 am
TYS
-
FCO
2 stops25h 40m
British Airways
Sun 3/158:35 pm
FCO
-
TYS
2 stops29h 30m
British Airways
Deal found 1/26$508
This United Airlines deal was found by Cheapflights users on 1/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 3/107:25 pm
TYS
-
FCO
2 stops31h 30m
United Airlines
Tue 3/177:05 am
FCO
-
TYS
2 stops18h 42m
United Airlines
Deal found 1/25$510
This American Airlines deal was found by Cheapflights users on 1/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 2/246:10 am
TYS
-
FCO
1 stop20h 50m
American Airlines
Tue 3/37:30 am
FCO
-
TYS
2 stops19h 10m
American Airlines
Deal found 1/27$517
This United Airlines deal was found by Cheapflights users on 1/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 2/32:25 pm
TYS
-
MXP
2 stops20h 15m
United Airlines
Mon 2/910:40 am
MXP
-
TYS
2 stops40h 12m
United Airlines
Deal found 1/25$519

Find flight deals from Knoxville to Italy

Keep the following information in mind while searching for Knoxville to Italy flight deals. Data was last updated January 27, 2026.

Most accurate provider

FlightHub
3 stars

Most trusted provider

FlightHub
3 stars

Round-trip from

$493
(United Airlines)

One-way from

$457
(oojo)

Popular in

May

Cheapest in

December

Average price

$1,103
Provider with most accurate pricing for Knoxville McGhee Tyson-Rome (ROM) flight deals.
Search Deals
Provider most trusted by Cheapflights users for Knoxville McGhee Tyson-Rome (ROM) flights.
Search Deals
From Knoxville McGhee Tyson to Italy
Search Deals
One-way flight from Knoxville McGhee Tyson to Italy
Search Deals
Highest demand for flights based on searches. 17% potential increase in price ($211 potential increase over avg. RT price).
Search Deals
Cheapest flight prices on average. 4% potential price decrease ($45 potential savings vs. average RT price).
Search Deals
Average for round-trip flights in January 2026
Search Deals

Cheapflights Fare Finder

 
Customize your flight search to find flights from Knoxville to Italy that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated January 27, 2026.
Use the filters below to find and compare flights from Knoxville to Italy that are best for you.

Fly from

Knoxville

Fly to

Italy

Route

Depart

Return

Price

KnoxvilleRome

TYS - FCO

TYSFCO

Knoxville McGhee Tyson

Tue 2/24

10:53 am-7:45 am

1 stop14h 52m

Rome Fiumicino

Tue 3/3

1:05 pm-8:37 pm

2 stops37h 32m

$493

KnoxvilleRome

TYS - FCO

TYSFCO

Knoxville McGhee Tyson

Tue 2/24

7:25 pm-11:05 am

2 stops33h 40m

Rome Fiumicino

Tue 3/3

1:05 pm-7:29 pm

2 stops36h 24m

$502

KnoxvilleFlorence

TYS - FLR

TYSFLR

Knoxville McGhee Tyson

Wed 3/11

1:53 pm-11:00 am

2 stops16h 07m

Florence Peretola

Wed 3/18

6:30 am-7:29 pm

2 stops17h 59m

$502

KnoxvilleVenice

TYS - VCE

TYSVCE

Knoxville McGhee Tyson

Thu 3/12

9:40 am-11:15 am

2 stops20h 35m

Venice Marco Polo

Thu 3/19

1:50 pm-7:29 pm

2 stops34h 39m

$505

KnoxvilleMilan

TYS - LIN

TYSLIN

Knoxville McGhee Tyson

Fri 3/20

2:21 pm-11:55 am

2 stops16h 34m

Milan Linate

Wed 3/25

2:55 pm-10:49 am

2 stops24h 54m

$507

KnoxvilleRome

TYS - FCO

TYSFCO

Knoxville McGhee Tyson

Tue 2/24

12:00 pm-10:30 am

1 stop16h 30m

Rome Fiumicino

Tue 3/3

12:40 pm-11:52 pm

1 stop17h 12m

$508

KnoxvilleRome

TYS - FCO

TYSFCO

Knoxville McGhee Tyson

Tue 3/10

11:18 am-6:55 am

1 stop14h 37m

Rome Fiumicino

Tue 3/17

9:05 am-9:06 pm

1 stop17h 01m

$508

KnoxvilleRome

TYS - FCO

TYSFCO

Knoxville McGhee Tyson

Tue 3/10

7:25 pm-7:55 am

2 stops31h 30m

Rome Fiumicino

Tue 3/17

7:05 am-8:47 pm

2 stops18h 42m

$510

KnoxvilleRome

TYS - FCO

TYSFCO

Knoxville McGhee Tyson

Tue 2/24

6:10 am-9:00 am

1 stop20h 50m

Rome Fiumicino

Tue 3/3

7:30 am-8:40 pm

2 stops19h 10m

$517

KnoxvilleTurin

TYS - TRN

TYSTRN

Knoxville McGhee Tyson

Wed 4/15

9:40 am-1:30 pm

2 stops21h 50m

Turin Citta Di Torino

Wed 4/22

9:55 am-11:03 pm

2 stops19h 08m

$565

Flights are sorted by cheapest round-trip flights first.

Deals found on 1/26

Showing 1-10 of 48 results
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Best time to book a flight from Knoxville to Italy

Have a flexible travel schedule? Discover the best time to fly to Italy from Knoxville with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Knoxville to Italy

What is the cheapest month to book a flight from Knoxville to Italy?

Currently, October is the cheapest month in which you can book a flight from Knoxville to Italy (average of $499). Flying from Knoxville to Italy in June is currently the most expensive (average of $1,141). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

Reviews of airlines servicing Italy

Get insights into the airlines that provide service to Italy. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Italy. Reviews last updated January 27, 2026.
See what other customers who have flown with Delta, KLM, and United Airlines from Knoxville to Italy have to say. You can also see how each airline compares in terms of entertainment options, comfort, food, crew/service, and boarding process.
Delta
7.9
Good
8,119 reviews

Crew

8.5

Comfort

7.9

Entertainment

7.8

Overall

7.9

Boarding

8.1

Food

7.2

Reviews

1 / 20
6.0
Good

Jim,Nov 2025

AVL - ATL

The exit row seats without a seat in front are great for leg room but don’t have a fold out entertainment console so you’re forced to use the screen several feet in front of you (there is, at least, a remote). Best to bring a tablet loaded with entertainment or a book.
Delta
7.9
Good
8,119 reviews
Delta
7.9
Good
8,119 reviews

Crew

8.5

Comfort

7.9

Entertainment

7.8

Overall

7.9

Boarding

8.1

Food

7.2

Reviews

1 / 20
6.0
Good

Jim,Nov 2025

AVL - ATL

The exit row seats without a seat in front are great for leg room but don’t have a fold out entertainment console so you’re forced to use the screen several feet in front of you (there is, at least, a remote). Best to bring a tablet loaded with entertainment or a book.
KLM
7.7
Good
1,443 reviews
Delta
7.9
Good
8,119 reviews

Crew

8.5

Comfort

7.9

Entertainment

7.8

Overall

7.9

Boarding

8.1

Food

7.2

Reviews

1 / 20
6.0
Good

Jim,Nov 2025

AVL - ATL

The exit row seats without a seat in front are great for leg room but don’t have a fold out entertainment console so you’re forced to use the screen several feet in front of you (there is, at least, a remote). Best to bring a tablet loaded with entertainment or a book.
United Airlines
7.4
Good
9,205 reviews
Delta
7.9
Good
8,119 reviews

Crew

8.5

Comfort

7.9

Entertainment

7.8

Overall

7.9

Boarding

8.1

Food

7.2

Reviews

1 / 20
6.0
Good

Jim,Nov 2025

AVL - ATL

The exit row seats without a seat in front are great for leg room but don’t have a fold out entertainment console so you’re forced to use the screen several feet in front of you (there is, at least, a remote). Best to bring a tablet loaded with entertainment or a book.
American Airlines
7.2
Good
11,197 reviews
Delta
7.9
Good
8,119 reviews

Crew

8.5

Comfort

7.9

Entertainment

7.8

Overall

7.9

Boarding

8.1

Food

7.2

Reviews

1 / 20
6.0
Good

Jim,Nov 2025

AVL - ATL

The exit row seats without a seat in front are great for leg room but don’t have a fold out entertainment console so you’re forced to use the screen several feet in front of you (there is, at least, a remote). Best to bring a tablet loaded with entertainment or a book.
British Airways
6.7
Okay
7,702 reviews
Delta
7.9
Good
8,119 reviews

Crew

8.5

Comfort

7.9

Entertainment

7.8

Overall

7.9

Boarding

8.1

Food

7.2

Reviews

1 / 20
6.0
Good

Jim,Nov 2025

AVL - ATL

The exit row seats without a seat in front are great for leg room but don’t have a fold out entertainment console so you’re forced to use the screen several feet in front of you (there is, at least, a remote). Best to bring a tablet loaded with entertainment or a book.

Related info for your journey

Find useful and relevant information for your journey from Knoxville to Italy. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • What airport do you fly from for flights from Knoxville to Italy?

    For a flight from Knoxville to Italy, you will be flying from McGhee Tyson. Knoxville McGhee Tyson (TYS) is just 11.3 mi from the center of the city.

  • How long is the flight from Knoxville to Italy?

    There are many flights that can get you from Knoxville to Italy in 14h 52m. Fly via United Airlines, Air Canada, or KLM to get the fastest option. Airlines will cover a distance of 4908 mi. This flight may include one or multiple stops.

  • What are the most popular routes from Knoxville to Italy?

    The most popular flight routes from Knoxville to Italy are Knoxville McGhee Tyson - Rome Fiumicino, Knoxville McGhee Tyson - Milan Linate and Knoxville McGhee Tyson - Milan Malpensa.

  • Can I find deals for flights from Knoxville to Italy that include hotel bookings?

    Yes. In addition to deals on Knoxville to Italy flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Knoxville to Italy?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Knoxville to Italy.

  • Can I find deals for business class flights from Knoxville to Italy?

    Yes. Cheapflights offers flight deals from Knoxville to Italy by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Knoxville to Italy?

    Currently, October is the cheapest month in which you can book a flight from Knoxville to Italy (average of $499). Flying from Knoxville to Italy in June is currently the most expensive (average of $1,141). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

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Alternative routes for Knoxville to Italy

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Top 5 airlines flying from Knoxville to Italy

Discover the top 5 airlines that operate flights from Knoxville to Italy. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated January 27, 2026.
AirlineCheapestAverageFlexibilityOn-time
United AirlinesCheapest$500Average$994FlexibilityNo cancel feeOn-time69%
DeltaCheapest$501Average$1,075FlexibilityNo cancel feeOn-timeN/A
American AirlinesCheapest$679Average$1,111FlexibilityNo cancel feeOn-time71%
LufthansaCheapest$716Average$1,026FlexibilityNo cancel feeOn-time76%
British AirwaysCheapest$765Average$874FlexibilityNo cancel feeOn-time70%

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