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Italy

$272+ Cheap flights from Knoxville (TYS) to Italy

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 9/30. Fares are subject to change and may not be available on all flights or dates of travel.
TYS — NAP
Aug 4 — Aug 111
Mon 8/4
Mon 8/11
1 adult, Economy
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Cheap flight deals from Knoxville to Italy

Keep the following information in mind while searching for Knoxville to Italy flight deals. Data was last updated July 30, 2025.

Round-trip from

$548
(Kiwi.com)

One-way from

$272
(Kiwi.com)

Popular in

May

Cheapest in

November

Average price

$1,190
From Knoxville McGhee Tyson to Italy
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One-way flight from Knoxville McGhee Tyson to Italy
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Highest demand for flights based on searches. 19% potential increase in price ($247 potential increase over avg. RT price).
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Cheapest flight prices on average. 4% potential price decrease ($42 potential savings vs. average RT price).
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Average for round-trip flights in July 2025
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Find flight deals from Knoxville to Italy

Cheapest flights from Knoxville to Italy
Explore the most affordable flight options available from Knoxville to Italy. Find the lowest fares from popular airlines and budget airlines, with prices last updated on July 30, 2025.

This Kiwi.com deal was found by Cheapflights users on 7/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 10/277:15 amTYS - FCO
1 stop25h 15mMultiple Airlines
Thu 11/67:10 pmFCO - TYS
1 stop22h 50mMultiple Airlines
Deal found 7/28$548
This United Airlines deal was found by Cheapflights users on 7/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 11/127:00 amTYS - FCO
2 stops19h 55mUnited Airlines
Fri 11/211:15 pmFCO - TYS
2 stops31h 28mUnited Airlines
Deal found 7/30$582
This Air Canada deal was found by Cheapflights users on 7/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Air Canada is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 11/125:45 amTYS - FCO
2 stops21h 10mAir Canada
Fri 11/211:15 pmFCO - TYS
2 stops31h 28mAir Canada
Deal found 7/28$583
This Ovago deal was found by Cheapflights users on 7/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Ovago is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 10/265:37 pmTYS - FCO
2 stops18h 18mBritish Airways
Thu 11/67:40 amFCO - TYS
2 stops19h 44mBritish Airways
Deal found 7/29$633
This Scandinavian Airlines deal was found by Cheapflights users on 7/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Scandinavian Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/243:48 pmTYS - FCO
2 stops38h 07mScandinavian Airlines
Sat 11/811:55 amFCO - TYS
2 stops39h 48mScandinavian Airlines
Deal found 7/29$654
This FlightHub deal was found by Cheapflights users on 7/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure FlightHub is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 10/227:26 pmTYS - CTA
2 stops16h 19mLufthansa
Thu 11/65:40 pmCTA - TYS
2 stops56h 40mLufthansa
Deal found 7/28$680
This Gotogate deal was found by Cheapflights users on 7/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Gotogate is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 11/197:20 pmTYS - FCO
2 stops21h 30mLufthansa
Fri 11/287:05 amFCO - TYS
2 stops22h 54mLufthansa
Deal found 7/27$693
This Delta deal was found by Cheapflights users on 7/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 11/1812:00 pmTYS - FCO
1 stop16h 30mDelta
Wed 11/2612:40 pmFCO - TYS
1 stop17h 06mDelta
Deal found 7/27$694
This United Airlines deal was found by Cheapflights users on 7/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 11/25:45 amTYS - VCE
2 stops26h 40mUnited Airlines
Sat 11/83:05 pmVCE - TYS
2 stops35h 15mUnited Airlines
Deal found 7/29$714
This KLM deal was found by Cheapflights users on 7/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure KLM is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/246:04 pmTYS - CTA
2 stops16h 06mKLM
Thu 11/610:10 amCTA - TYS
2 stops17h 03mKLM
Deal found 7/28$721
This Lufthansa deal was found by Cheapflights users on 7/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Lufthansa is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 12/37:25 pmTYS - AOI
2 stops15h 10mLufthansa
Sun 12/79:55 amAOI - TYS
2 stops39h 34mLufthansa
Deal found 7/27$734
This Ovago deal was found by Cheapflights users on 7/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Ovago is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/233:03 pmTYS - CTA
2 stops20h 52mBritish Airways
Sat 11/86:00 pmCTA - TYS
2 stops33h 24mBritish Airways
Deal found 7/28$747

Cheapflights Fare Finder

 
Customize your flight search to find flights from Knoxville to Italy that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated July 30, 2025.
Use the filters below to find and compare flights from Knoxville to Italy that are best for you.

Fly from

Knoxville

Fly to

Italy

Route

Depart

Return

Price

KnoxvilleRome

TYS - FCO

TYSFCO

Knoxville McGhee Tyson

Wed 11/12

9:50 am-8:55 am

2 stops17h 05m

Rome Fiumicino

Fri 11/21

1:15 pm-2:43 pm

2 stops31h 28m

$582

KnoxvilleRome

TYS - FCO

TYSFCO

Knoxville McGhee Tyson

Wed 11/12

3:40 pm-9:00 am

1 stop11h 20m

Rome Fiumicino

Fri 11/21

1:10 pm-9:04 pm

1 stop13h 54m

$605

KnoxvilleRome

TYS - FCO

TYSFCO

Knoxville McGhee Tyson

Sun 10/26

5:37 pm-4:55 pm

2 stops18h 18m

Rome Fiumicino

Thu 11/6

7:40 am-9:24 pm

2 stops19h 44m

$633

KnoxvilleRome

TYS - FCO

TYSFCO

Knoxville McGhee Tyson

Fri 10/24

3:48 pm-11:55 am

2 stops38h 07m

Rome Fiumicino

Sat 11/8

11:55 am-9:43 pm

2 stops39h 48m

$654

KnoxvilleRome

TYS - FCO

TYSFCO

Knoxville McGhee Tyson

Sun 11/16

12:00 pm-7:55 am

1 stop13h 55m

Rome Fiumicino

Wed 11/26

10:05 am-6:19 pm

1 stop14h 14m

$694

KnoxvilleVenice

TYS - VCE

TYSVCE

Knoxville McGhee Tyson

Sun 11/2

5:45 am-2:25 pm

2 stops26h 40m

Venice Marco Polo

Sat 11/8

3:05 pm-8:20 pm

2 stops35h 15m

$714

KnoxvilleMilan

TYS - MXP

TYSMXP

Knoxville McGhee Tyson

Tue 9/2

7:25 pm-6:45 pm

2 stops17h 20m

Milan Malpensa

Tue 9/16

12:15 pm-8:56 pm

2 stops38h 41m

$753

KnoxvilleMilan

TYS - MXP

TYSMXP

Knoxville McGhee Tyson

Tue 9/2

6:12 pm-11:40 pm

2 stops47h 28m

Milan Malpensa

Tue 9/16

1:20 pm-9:14 pm

1 stop13h 54m

$755

KnoxvilleFlorence

TYS - FLR

TYSFLR

Knoxville McGhee Tyson

Thu 8/14

10:55 am-2:05 pm

2 stops21h 10m

Florence Peretola

Tue 8/19

6:40 am-7:53 pm

2 stops19h 13m

$780

KnoxvilleMilan

TYS - LIN

TYSLIN

Knoxville McGhee Tyson

Tue 9/2

2:00 pm-12:20 pm

2 stops16h 20m

Milan Linate

Tue 9/16

12:45 pm-11:57 pm

2 stops17h 12m

$789

Flights are sorted by cheapest round-trip flights first.

Deals found on 7/29

Showing 1-10 of 44 results
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Best time to book a flight from Knoxville to Italy

Have a flexible travel schedule? Discover the best time to fly to Italy from Knoxville with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Knoxville to Italy

What is the cheapest month to book a flight from Knoxville to Italy?

Currently, January is the cheapest month in which you can book a flight from Knoxville to Italy (average of $703). Flying from Knoxville to Italy in June is currently the most expensive (average of $1,210). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

What is the cheapest time of day to fly from TYS to IT?

Find hourly flight availability from Knoxville to Italy. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated July 30, 2025.

When flying from Knoxville to Italy, the time of day you decide to fly out makes little to no difference towards the overall price you’ll pay on tickets.

Reviews of airlines servicing Italy

Get insights into the airlines that provide service to Italy. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Italy. Reviews last updated July 30, 2025.
See what other customers who have flown with Delta, KLM, and United Airlines from Knoxville to Italy have to say. You can also see how each airline compares in terms of entertainment options, comfort, food, crew/service, and boarding process.
Delta
8.0
Very good
7,980 reviews

Food

7.3

Boarding

8.2

Comfort

7.9

Crew

8.5

Overall

8.0

Entertainment

7.9

Reviews

1 / 20
10.0
Excellent

Kim,May 2025

PIH - SLC

This trip was fine even with delay I had plenty of time to get connection flight!
Delta
8.0
Very good
7,980 reviews
Delta
8.0
Very good
7,980 reviews

Food

7.3

Boarding

8.2

Comfort

7.9

Crew

8.5

Overall

8.0

Entertainment

7.9

Reviews

1 / 20
10.0
Excellent

Kim,May 2025

PIH - SLC

This trip was fine even with delay I had plenty of time to get connection flight!
KLM
7.8
Good
1,383 reviews
Delta
8.0
Very good
7,980 reviews

Food

7.3

Boarding

8.2

Comfort

7.9

Crew

8.5

Overall

8.0

Entertainment

7.9

Reviews

1 / 20
10.0
Excellent

Kim,May 2025

PIH - SLC

This trip was fine even with delay I had plenty of time to get connection flight!
United Airlines
7.4
Good
8,896 reviews
Delta
8.0
Very good
7,980 reviews

Food

7.3

Boarding

8.2

Comfort

7.9

Crew

8.5

Overall

8.0

Entertainment

7.9

Reviews

1 / 20
10.0
Excellent

Kim,May 2025

PIH - SLC

This trip was fine even with delay I had plenty of time to get connection flight!
Scandinavian Airlines
7.3
Good
1,453 reviews
Delta
8.0
Very good
7,980 reviews

Food

7.3

Boarding

8.2

Comfort

7.9

Crew

8.5

Overall

8.0

Entertainment

7.9

Reviews

1 / 20
10.0
Excellent

Kim,May 2025

PIH - SLC

This trip was fine even with delay I had plenty of time to get connection flight!
American Airlines
7.2
Good
10,000 reviews
Delta
8.0
Very good
7,980 reviews

Food

7.3

Boarding

8.2

Comfort

7.9

Crew

8.5

Overall

8.0

Entertainment

7.9

Reviews

1 / 20
10.0
Excellent

Kim,May 2025

PIH - SLC

This trip was fine even with delay I had plenty of time to get connection flight!

Related info for your journey

Find useful and relevant information for your journey from Knoxville to Italy. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • What airport do you fly from for flights from Knoxville to Italy?

    For a flight from Knoxville to Italy, you will be flying from McGhee Tyson. Knoxville McGhee Tyson (TYS) is just 11.3 mi from the center of the city.

  • What are the cheapest airlines to fly from Knoxville to Italy one-way?

    The cheapest airline one-way is British Airways, with whom users have recently found tickets for as low as $523. However, be on the lookout for offers from United Airlines and American Airlines, as they are both options that can get you from Knoxville to Italy for a low price.

  • What are the most popular routes from Knoxville to Italy?

    The most popular flight routes from Knoxville to Italy are Knoxville McGhee Tyson - Rome Fiumicino, Knoxville McGhee Tyson - Florence Peretola and Knoxville McGhee Tyson - Milan Malpensa.

  • Can I find deals for flights from Knoxville to Italy that include hotel bookings?

    Yes. In addition to deals on Knoxville to Italy flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Knoxville to Italy?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Knoxville to Italy.

  • Can I find deals for business class flights from Knoxville to Italy?

    Yes. Cheapflights offers flight deals from Knoxville to Italy by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Knoxville to Italy?

    Currently, January is the cheapest month in which you can book a flight from Knoxville to Italy (average of $703). Flying from Knoxville to Italy in June is currently the most expensive (average of $1,210). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

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See prices for flight routes from nearby airports that may be better suited for you.
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Top 5 airlines flying from Knoxville to Italy

Discover the top 5 airlines that operate flights from Knoxville to Italy. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated July 30, 2025.
AirlineCheapestAverageFlexibilityOn-time
British AirwaysCheapest$700Average$1,120FlexibilityNo cancel feeOn-time70%
United AirlinesCheapest$702Average$1,282FlexibilityNo cancel feeOn-time69%
DeltaCheapest$717Average$1,068FlexibilityNo cancel feeOn-timeN/A
American AirlinesCheapest$718Average$1,250FlexibilityNo cancel feeOn-time71%
LufthansaCheapest$793Average$1,086FlexibilityNo cancel feeOn-time76%

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