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Italy

$360+ Cheap flights from Knoxville (TYS) to Italy

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 4/30. Fares are subject to change and may not be available on all flights or dates of travel.
TYS — NAP
Apr 13 — Apr 201
Mon 4/13
Mon 4/20
1 adult, Economy
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Cheap flight deals from Knoxville to Italy

Cheapest flights from Knoxville to Italy
Explore the most affordable flight options available from Knoxville to Italy. Find the lowest fares from popular airlines and budget airlines, with prices last updated on March 14, 2026.

This United Airlines deal was found by Cheapflights users on 3/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 11/135:45 am
TYS
-
LIN
2 stops24h 35m
United Airlines
Tue 11/176:10 am
LIN
-
TYS
2 stops23h 27m
United Airlines
Deal found 3/12$626
This Iberia deal was found by Cheapflights users on 3/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Iberia is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 8/173:01 pm
TYS
-
FCO
2 stops21h 14m
Iberia
Tue 8/258:25 pm
FCO
-
TYS
2 stops30h 58m
Iberia
Deal found 3/9$662
This FlightHub deal was found by Cheapflights users on 3/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure FlightHub is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 11/254:00 pm
TYS
-
MXP
2 stops34h 25m
Scandinavian Airlines
Tue 12/18:00 pm
MXP
-
TYS
2 stops33h 46m
Scandinavian Airlines
Deal found 3/13$666
This Booking.com deal was found by Cheapflights users on 3/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Booking.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 8/173:01 pm
TYS
-
FCO
2 stops18h 59m
British Airways
Tue 8/2512:15 pm
FCO
-
TYS
1 stop15h 29m
British Airways
Deal found 3/9$666
This United Airlines deal was found by Cheapflights users on 3/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 11/252:00 pm
TYS
-
MXP
1 stop17h 05m
United Airlines
Tue 12/11:05 pm
MXP
-
TYS
2 stops30h 13m
United Airlines
Deal found 3/13$672
This Booking.com deal was found by Cheapflights users on 3/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Booking.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 8/86:07 pm
TYS
-
FCO
1 stop34h 13m
British Airways
Wed 8/1910:00 am
FCO
-
TYS
1 stop17h 23m
British Airways
Deal found 3/9$674
This United Airlines deal was found by Cheapflights users on 3/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 12/110:50 am
TYS
-
VCE
2 stops16h 05m
United Airlines
Thu 12/36:45 am
VCE
-
TYS
2 stops36h 35m
United Airlines
Deal found 3/11$675
This United Airlines deal was found by Cheapflights users on 3/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 12/67:00 am
TYS
-
MXP
2 stops27h 40m
United Airlines
Wed 12/99:45 am
MXP
-
TYS
2 stops17h 20m
United Airlines
Deal found 3/12$687
This United Airlines deal was found by Cheapflights users on 3/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 8/171:35 pm
TYS
-
FCO
1 stop12h 40m
United Airlines
Tue 8/2510:20 am
FCO
-
TYS
1 stop16h 08m
United Airlines
Deal found 3/9$690
This Booking.com deal was found by Cheapflights users on 3/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Booking.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 8/87:19 pm
TYS
-
FCO
2 stops34h 26m
Air Canada
Wed 8/1911:30 am
FCO
-
TYS
2 stops33h 07m
Air Canada
Deal found 3/9$693
This Booking.com deal was found by Cheapflights users on 3/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Booking.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 11/255:45 am
TYS
-
MXP
2 stops22h 10m
Air Canada
Tue 12/11:05 pm
MXP
-
TYS
3 stops50h 55m
Air Canada
Deal found 3/12$695
This United Airlines deal was found by Cheapflights users on 3/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 8/85:57 pm
TYS
-
FCO
2 stops33h 18m
United Airlines
Wed 8/1910:20 am
FCO
-
TYS
1 stop19h 37m
United Airlines
Deal found 3/9$699

Find flight deals from Knoxville to Italy

Keep the following information in mind while searching for Knoxville to Italy flight deals. Data was last updated March 14, 2026.

Most accurate provider

FlightHub
3 stars

Most trusted provider

FlightHub
3 stars

Round-trip from

$662
(Iberia)

One-way from

$360
(Kiwi.com)

Popular in

June

Cheapest in

December

Average price

$691
Provider with most accurate pricing for Knoxville McGhee Tyson-Rome (ROM) flight deals.
Search Deals
Provider most trusted by Cheapflights users for Knoxville McGhee Tyson-Rome (ROM) flights.
Search Deals
From Knoxville McGhee Tyson to Italy
Search Deals
One-way flight from Knoxville McGhee Tyson to Italy
Search Deals
Highest demand for flights based on searches. 20% potential increase in price ($229 potential increase over avg. RT price).
Search Deals
Cheapest flight prices on average. 3% potential price decrease ($28 potential savings vs. average RT price).
Search Deals
Average for round-trip flights in March 2026
Search Deals

Cheapflights Fare Finder

 
Customize your flight search to find flights from Knoxville to Italy that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated March 14, 2026.
Use the filters below to find and compare flights from Knoxville to Italy that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

Cheapest round-trip

KnoxvilleTurin

TYS - TRN

TYSTRN

Knoxville McGhee Tyson

Fri 4/17

2:25 pm-4:40 pm

2 stops20h 15m

Turin Citta Di Torino

Fri 4/24

9:55 am-10:34 pm

2 stops18h 39m

$712

KnoxvilleRome

TYS - FCO

TYSFCO

Knoxville McGhee Tyson

Sat 8/15

5:57 pm-7:55 am

1 stop31h 58m

Rome Fiumicino

Sat 8/22

10:00 am-8:28 pm

2 stops16h 28m

$744

KnoxvilleTurin

TYS - TRN

TYSTRN

Knoxville McGhee Tyson

Fri 4/17

10:49 am-10:55 pm

2 stops30h 06m

Turin Citta Di Torino

Fri 4/24

6:15 am-10:34 pm

2 stops22h 19m

$752

KnoxvilleFlorence

TYS - FLR

TYSFLR

Knoxville McGhee Tyson

Fri 4/17

5:53 pm-8:15 pm

2 stops20h 22m

Florence Peretola

Fri 4/24

6:30 am-10:34 pm

2 stops22h 04m

$798

KnoxvilleFlorence

TYS - FLR

TYSFLR

Knoxville McGhee Tyson

Fri 4/24

5:06 pm-10:20 pm

2 stops23h 14m

Florence Peretola

Fri 5/1

7:05 am-8:18 pm

2 stops19h 13m

$801

KnoxvilleMilan

TYS - LIN

TYSLIN

Knoxville McGhee Tyson

Mon 5/11

7:00 am-12:20 pm

2 stops23h 20m

Milan Linate

Mon 5/18

12:40 pm-8:45 pm

2 stops38h 05m

$806

KnoxvilleMilan

TYS - MXP

TYSMXP

Knoxville McGhee Tyson

Sat 5/16

5:55 pm-10:20 am

2 stops34h 25m

Milan Malpensa

Wed 5/27

12:20 pm-11:54 pm

2 stops41h 34m

$807
Quickest round-trip

KnoxvilleMilan

TYS - MXP

TYSMXP

Knoxville McGhee Tyson

Mon 5/4

5:06 pm-1:45 pm

2 stops14h 39m

Milan Malpensa

Thu 5/14

2:20 pm-9:57 pm

1 stop13h 37m

$812

KnoxvilleMilan

TYS - MXP

TYSMXP

Knoxville McGhee Tyson

Thu 4/23

7:00 am-7:30 am

2 stops18h 30m

Milan Malpensa

Thu 4/30

12:20 pm-4:49 pm

2 stops34h 29m

$821

KnoxvilleRome

TYS - FCO

TYSFCO

Knoxville McGhee Tyson

Tue 9/8

5:45 am-7:35 am

2 stops19h 50m

Rome Fiumicino

Tue 9/22

9:45 am-8:48 pm

1 stop17h 03m

$829

Flights are sorted by cheapest round-trip flights first.

Deals found on 3/14

Showing 1-10 of 50 resultsSorted by cheapest first
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Best time to book a flight from Knoxville to Italy

Have a flexible travel schedule? Discover the best time to fly to Italy from Knoxville with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Knoxville to Italy

What is the cheapest month to book a flight from Knoxville to Italy?

Currently, October is the cheapest month in which you can book a flight from Knoxville to Italy (average of $489). Flying from Knoxville to Italy in June is currently the most expensive (average of $1,107). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

Reviews of airlines servicing Italy

Get insights into the airlines that provide service to Italy. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Italy. Reviews last updated March 14, 2026.
See what other customers who have flown with Delta,United Airlines, andAmerican Airlines from Knoxville to Italy have to say. You can also see how each airline compares in terms of entertainment options, comfort, food, crew/service, and boarding process.
Delta
7.9
Good
8,291 reviews

Comfort

7.9

Food

7.2

Overall

7.9

Crew

8.5

Boarding

8.1

Entertainment

7.8

Reviews

1 / 20
6.0
Good

Jim,Nov 2025

AVL - ATL

The exit row seats without a seat in front are great for leg room but don’t have a fold out entertainment console so you’re forced to use the screen several feet in front of you (there is, at least, a remote). Best to bring a tablet loaded with entertainment or a book.
Delta
7.9
Good
8,291 reviews
Delta
7.9
Good
8,291 reviews

Comfort

7.9

Food

7.2

Overall

7.9

Crew

8.5

Boarding

8.1

Entertainment

7.8

Reviews

1 / 20
6.0
Good

Jim,Nov 2025

AVL - ATL

The exit row seats without a seat in front are great for leg room but don’t have a fold out entertainment console so you’re forced to use the screen several feet in front of you (there is, at least, a remote). Best to bring a tablet loaded with entertainment or a book.
United Airlines
7.4
Good
9,423 reviews
Delta
7.9
Good
8,291 reviews

Comfort

7.9

Food

7.2

Overall

7.9

Crew

8.5

Boarding

8.1

Entertainment

7.8

Reviews

1 / 20
6.0
Good

Jim,Nov 2025

AVL - ATL

The exit row seats without a seat in front are great for leg room but don’t have a fold out entertainment console so you’re forced to use the screen several feet in front of you (there is, at least, a remote). Best to bring a tablet loaded with entertainment or a book.
American Airlines
7.1
Good
11,464 reviews
Delta
7.9
Good
8,291 reviews

Comfort

7.9

Food

7.2

Overall

7.9

Crew

8.5

Boarding

8.1

Entertainment

7.8

Reviews

1 / 20
6.0
Good

Jim,Nov 2025

AVL - ATL

The exit row seats without a seat in front are great for leg room but don’t have a fold out entertainment console so you’re forced to use the screen several feet in front of you (there is, at least, a remote). Best to bring a tablet loaded with entertainment or a book.
Lufthansa
6.8
Okay
7,848 reviews
Delta
7.9
Good
8,291 reviews

Comfort

7.9

Food

7.2

Overall

7.9

Crew

8.5

Boarding

8.1

Entertainment

7.8

Reviews

1 / 20
6.0
Good

Jim,Nov 2025

AVL - ATL

The exit row seats without a seat in front are great for leg room but don’t have a fold out entertainment console so you’re forced to use the screen several feet in front of you (there is, at least, a remote). Best to bring a tablet loaded with entertainment or a book.
British Airways
6.7
Okay
7,786 reviews
Delta
7.9
Good
8,291 reviews

Comfort

7.9

Food

7.2

Overall

7.9

Crew

8.5

Boarding

8.1

Entertainment

7.8

Reviews

1 / 20
6.0
Good

Jim,Nov 2025

AVL - ATL

The exit row seats without a seat in front are great for leg room but don’t have a fold out entertainment console so you’re forced to use the screen several feet in front of you (there is, at least, a remote). Best to bring a tablet loaded with entertainment or a book.

Related info for your journey

Find useful and relevant information for your journey from Knoxville to Italy. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • What airport do you fly from for flights from Knoxville to Italy?

    For a flight from Knoxville to Italy, you will be flying from McGhee Tyson. Knoxville McGhee Tyson (TYS) is just 11.3 mi from the center of the city.

  • How long is the flight from Knoxville to Italy?

    There are many flights that can get you from Knoxville to Italy in 14h 39m. Fly via Lufthansa, United Airlines, or British Airways to get the fastest option. Airlines will cover a distance of 4624 mi. This flight may include one or multiple stops.

  • What are the most popular routes from Knoxville to Italy?

    The most popular flight routes from Knoxville to Italy are Knoxville McGhee Tyson - Rome Fiumicino, Knoxville McGhee Tyson - Milan Malpensa and Knoxville McGhee Tyson - Milan Linate.

  • Can I find deals for flights from Knoxville to Italy that include hotel bookings?

    Yes. In addition to deals on Knoxville to Italy flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Knoxville to Italy?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Knoxville to Italy.

  • Can I find deals for business class flights from Knoxville to Italy?

    Yes. Cheapflights offers flight deals from Knoxville to Italy by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Knoxville to Italy?

    Currently, October is the cheapest month in which you can book a flight from Knoxville to Italy (average of $489). Flying from Knoxville to Italy in June is currently the most expensive (average of $1,107). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

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Top 4 airlines flying from Knoxville to Italy

Discover the top 4 airlines that operate flights from Knoxville to Italy. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated March 14, 2026.
AirlineCheapestAverageFlexibilityOn-time
United AirlinesCheapest$564Average$983FlexibilityNo cancel feeOn-time69%
DeltaCheapest$612Average$1,119FlexibilityNo cancel feeOn-timeN/A
British AirwaysCheapest$765Average$859FlexibilityNo cancel feeOn-time70%
LufthansaCheapest$787Average$986FlexibilityNo cancel feeOn-time76%

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