HomeSearch by dateVacation packagesHotelsFlight dealsCar rentalTravel tips & news
Italy

$321+ Cheap flights from Charleston (CHS) to Italy

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 12/10. Fares are subject to change and may not be available on all flights or dates of travel.
CHS — NAP
Nov 17 — Nov 241
Mon 11/17
Mon 11/24
1 adult, Economy
We work with more than 300 partners to bring you better travel deals

Find cheap flights from Charleston to Italy with Cheapflights

1. Tell us where you want to go

Enter your travel information like dates, passengers, trip type (one-way or round trip), and preferred cabin class then click “Find deals”

2. Select your favorite providers

We find the providers serving your travel needs. Choose up to four travel providers to compare side-by-side for flights, hotels, or car rentals.

3. Compare prices and book

Review each provider’s pricing and select the best option for you! Book through your favorite provider’s website for a seamless experience.

Find flight deals from Charleston to Italy

Cheapest flights from Charleston to Italy
Explore the most affordable flight options available from Charleston to Italy. Find the lowest fares from popular airlines and budget airlines, with prices last updated on October 18, 2025.

This Mytrip deal was found by Cheapflights users on 10/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Mytrip is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 11/136:11 pmCHS - FCO
2 stops23h 54mMultiple Airlines
Wed 11/266:00 amFCO - CHS
2 stops31h 26mMultiple Airlines
Deal found 10/16$487
This Flighttix deal was found by Cheapflights users on 10/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Flighttix is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 11/137:45 pmCHS - FCO
2 stops31h 10mAir Canada
Wed 11/261:15 pmFCO - CHS
2 stops26h 53mAir Canada
Deal found 10/15$516
This Air Canada deal was found by Cheapflights users on 10/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Air Canada is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 12/27:00 pmCHS - FCO
2 stops32h 25mAir Canada
Wed 12/101:10 pmFCO - CHS
2 stops40h 32mAir Canada
Deal found 10/16$532
This Kiwi.com deal was found by Cheapflights users on 10/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 11/146:11 pmCHS - FCO
1 stop14h 19mMultiple Airlines
Fri 11/217:10 pmFCO - CHS
1 stop18h 16mMultiple Airlines
Deal found 10/17$535
This United Airlines deal was found by Cheapflights users on 10/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 12/16:15 amCHS - FCO
1 stop19h 30mUnited Airlines
Mon 12/810:55 amFCO - CHS
2 stops33h 00mUnited Airlines
Deal found 10/17$539
This United Airlines deal was found by Cheapflights users on 10/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 11/137:45 pmCHS - FCO
1 stop30h 45mUnited Airlines
Wed 11/269:45 amFCO - CHS
2 stops17h 23mUnited Airlines
Deal found 10/15$543
This Flighttix deal was found by Cheapflights users on 10/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Flighttix is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 11/132:52 pmCHS - FCO
1 stop11h 38mLufthansa
Wed 11/2610:30 amFCO - CHS
1 stop19h 12mLufthansa
Deal found 10/15$546
This KLM deal was found by Cheapflights users on 10/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure KLM is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 12/112:51 pmCHS - FLR
2 stops14h 04mKLM
Mon 12/86:40 amFLR - CHS
2 stops16h 44mKLM
Deal found 10/16$547
This United Airlines deal was found by Cheapflights users on 10/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 12/14:38 pmCHS - BLQ
2 stops42h 27mUnited Airlines
Mon 12/81:20 pmBLQ - CHS
2 stops16h 22mUnited Airlines
Deal found 10/17$548
This KLM deal was found by Cheapflights users on 10/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure KLM is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 12/14:13 pmCHS - NAP
2 stops17h 37mKLM
Mon 12/86:15 amNAP - CHS
2 stops18h 01mKLM
Deal found 10/17$550
This United Airlines deal was found by Cheapflights users on 10/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 12/22:51 pmCHS - FCO
1 stop11h 39mUnited Airlines
Wed 12/107:00 amFCO - CHS
2 stops18h 01mUnited Airlines
Deal found 10/16$553
This Mytrip deal was found by Cheapflights users on 10/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Mytrip is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 11/159:02 amCHS - MXP
2 stops23h 03mMultiple Airlines
Sat 11/223:10 pmMXP - CHS
2 stops22h 16mMultiple Airlines
Deal found 10/16$553

Cheap flight deals from Charleston to Italy

Keep the following information in mind while searching for Charleston to Italy flight deals. Data was last updated October 18, 2025.

Most accurate provider

FlightHub
3 stars

Most trusted provider

FlightHub
3 stars

Round-trip from

$487
(Mytrip)

One-way from

$321
(Kiwi.com)

Popular in

June

Cheapest in

November

Average price

$976
Provider with most accurate pricing for Charleston-Rome (ROM) flight deals.
Search Deals
Provider most trusted by Cheapflights users for Charleston-Rome (ROM) flights.
Search Deals
From Charleston to Italy
Search Deals
One-way flight from Charleston to Italy
Search Deals
Highest demand for flights based on searches. 25% potential increase in price ($362 potential increase over avg. RT price).
Search Deals
Cheapest flight prices on average. 4% potential price decrease ($44 potential savings vs. average RT price).
Search Deals
Average for round-trip flights in October 2025
Search Deals

Cheapflights Fare Finder

 
Customize your flight search to find flights from Charleston to Italy that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated October 18, 2025.
Use the filters below to find and compare flights from Charleston to Italy that are best for you.

Fly from

Charleston

Fly to

Italy

Route

Depart

Return

Price

CharlestonMilan

CHS - MXP

CHSMXP

Charleston

Wed 1/7

7:45 pm-4:40 pm

2 stops14h 55m

Milan Malpensa

Tue 1/13

1:05 pm-7:04 pm

2 stops35h 59m

$514

CharlestonRome

CHS - FCO

CHSFCO

Charleston

Thu 11/13

7:45 pm-8:55 am

2 stops31h 10m

Rome Fiumicino

Wed 11/26

1:15 pm-10:08 am

2 stops26h 53m

$516

CharlestonMilan

CHS - MXP

CHSMXP

Charleston

Mon 2/9

6:00 am-10:25 am

2 stops22h 25m

Milan Malpensa

Sun 2/15

10:00 pm-8:52 pm

2 stops28h 52m

$525

CharlestonRome

CHS - FCO

CHSFCO

Charleston

Fri 12/5

6:00 am-9:25 am

2 stops21h 25m

Rome Fiumicino

Fri 12/12

1:10 pm-1:55 pm

2 stops30h 45m

$532

CharlestonRome

CHS - FCO

CHSFCO

Charleston

Fri 11/14

11:25 am-7:45 am

1 stop14h 20m

Rome Fiumicino

Fri 11/21

1:15 pm-7:23 pm

2 stops36h 08m

$532

CharlestonRome

CHS - FCO

CHSFCO

Charleston

Thu 11/13

6:15 am-7:45 am

1 stop19h 30m

Rome Fiumicino

Wed 11/26

1:15 pm-1:56 pm

2 stops30h 41m

$532

CharlestonRome

CHS - FCO

CHSFCO

Charleston

Fri 12/5

11:33 am-7:45 am

1 stop14h 12m

Rome Fiumicino

Fri 12/12

1:10 pm-3:10 pm

2 stops32h 00m

$532

CharlestonMilan

CHS - MXP

CHSMXP

Charleston

Wed 1/7

7:45 pm-4:40 pm

2 stops14h 55m

Milan Malpensa

Wed 1/14

9:45 am-5:59 pm

1 stop14h 14m

$537

CharlestonRome

CHS - FCO

CHSFCO

Charleston

Mon 12/1

6:15 am-7:45 am

1 stop19h 30m

Rome Fiumicino

Mon 12/8

10:55 am-1:55 pm

2 stops33h 00m

$539

CharlestonRome

CHS - FCO

CHSFCO

Charleston

Thu 11/13

2:52 pm-8:30 am

1 stop11h 38m

Rome Fiumicino

Wed 11/26

10:30 am-11:42 pm

1 stop19h 12m

$546

Flights are sorted by cheapest round-trip flights first.

Deals found on 10/17

Showing 1-10 of 37 results
1
2
3
4

Best time to book a flight from Charleston to Italy

Have a flexible travel schedule? Discover the best time to fly to Italy from Charleston with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Charleston to Italy

What is the cheapest month to book a flight from Charleston to Italy?

Currently, October is the cheapest month in which you can book a flight from Charleston to Italy (average of $181). Flying from Charleston to Italy in July is currently the most expensive (average of $859). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

What is the cheapest time of day to fly from CHS to IT?

Find hourly flight availability from Charleston to Italy. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated October 18, 2025.

It’s typically best to fly out from Charleston to Italy in the morning. Doing so could potentially save you 7% on the flight price compared to flying at noon, which is usually more expensive.

What is the cheapest day to fly from Charleston to Italy?

Use this chart to determine the cheapest time to fly round-trip from Charleston to Italy. Price data was last updated on December 16, 2024.

Travelers seeking maximum savings on their Charleston to Italy flight should consider departing on Sunday mornings when fares are most often at their lowest. Monday evenings flights should be avoided if possible as fares are typically the most expensive at this time.

Reviews of airlines servicing Italy

Get insights into the airlines that provide service to Italy. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Italy. Reviews last updated October 18, 2025.
Read through reviews of airlines operating flights from Charleston to Italy, such as Delta, KLM, and United Airlines. Reviews also offer insight into each airline's entertainment options, comfort, food, crew/service, and boarding process.
Delta
7.9
Good
7,977 reviews

Comfort

7.9

Entertainment

7.9

Crew

8.5

Food

7.3

Boarding

8.2

Overall

7.9

Reviews

1 / 20
8.0
Excellent

Matthew,Oct 2025

GSP - ATL

This is always a full flight since it is the connecting route to primary destinations through Atlanta. That said, the crew handles the full load well. Not much more to say, it is a short flight with no in-flight services due to the length.
Delta
7.9
Good
7,977 reviews
Delta
7.9
Good
7,977 reviews

Comfort

7.9

Entertainment

7.9

Crew

8.5

Food

7.3

Boarding

8.2

Overall

7.9

Reviews

1 / 20
8.0
Excellent

Matthew,Oct 2025

GSP - ATL

This is always a full flight since it is the connecting route to primary destinations through Atlanta. That said, the crew handles the full load well. Not much more to say, it is a short flight with no in-flight services due to the length.
KLM
7.7
Good
1,404 reviews
Delta
7.9
Good
7,977 reviews

Comfort

7.9

Entertainment

7.9

Crew

8.5

Food

7.3

Boarding

8.2

Overall

7.9

Reviews

1 / 20
8.0
Excellent

Matthew,Oct 2025

GSP - ATL

This is always a full flight since it is the connecting route to primary destinations through Atlanta. That said, the crew handles the full load well. Not much more to say, it is a short flight with no in-flight services due to the length.
United Airlines
7.4
Good
8,987 reviews
Delta
7.9
Good
7,977 reviews

Comfort

7.9

Entertainment

7.9

Crew

8.5

Food

7.3

Boarding

8.2

Overall

7.9

Reviews

1 / 20
8.0
Excellent

Matthew,Oct 2025

GSP - ATL

This is always a full flight since it is the connecting route to primary destinations through Atlanta. That said, the crew handles the full load well. Not much more to say, it is a short flight with no in-flight services due to the length.
American Airlines
7.2
Good
11,040 reviews
Delta
7.9
Good
7,977 reviews

Comfort

7.9

Entertainment

7.9

Crew

8.5

Food

7.3

Boarding

8.2

Overall

7.9

Reviews

1 / 20
8.0
Excellent

Matthew,Oct 2025

GSP - ATL

This is always a full flight since it is the connecting route to primary destinations through Atlanta. That said, the crew handles the full load well. Not much more to say, it is a short flight with no in-flight services due to the length.
British Airways
6.7
Okay
7,459 reviews
Delta
7.9
Good
7,977 reviews

Comfort

7.9

Entertainment

7.9

Crew

8.5

Food

7.3

Boarding

8.2

Overall

7.9

Reviews

1 / 20
8.0
Excellent

Matthew,Oct 2025

GSP - ATL

This is always a full flight since it is the connecting route to primary destinations through Atlanta. That said, the crew handles the full load well. Not much more to say, it is a short flight with no in-flight services due to the length.

Related info for your journey

Find useful and relevant information for your journey from Charleston to Italy. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • What airport do you fly from for flights from Charleston to Italy?

    If you book a flight to Italy from Charleston, you will be flying from Charleston, which is the city’s only airport. Charleston (CHS) is located 10.2 mi from the center of Charleston.

  • How long is the flight from Charleston to Italy?

    United Airlines, Air Canada, and Scandinavian Airlines can get you from Charleston to Italy in just under 14h 55m. Your travel time can differ by up to 16h 15m. Airlines will cover a distance of 4582 mi. When browsing for deals, the options you’ll see will be for both nonstop flights and flights with stops.

  • What are the most popular routes from Charleston to Italy?

    When deciding which route to take from Charleston to Italy consider Charleston - Rome Fiumicino, Charleston - Milan Malpensa or Charleston - Milan Linate as they are the most popular.

  • Can I find deals for flights from Charleston to Italy that include hotel bookings?

    Yes. In addition to deals on Charleston to Italy flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Charleston to Italy?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Charleston to Italy.

  • Can I find deals for business class flights from Charleston to Italy?

    Yes. Cheapflights offers flight deals from Charleston to Italy by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Charleston to Italy?

    Currently, October is the cheapest month in which you can book a flight from Charleston to Italy (average of $181). Flying from Charleston to Italy in July is currently the most expensive (average of $859). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

Browse thousands of different options on Cheapflights for your next trip

Toggle through the tabs below to find thousands of options on Cheapflights for your next trip.

Alternative routes for Charleston to Italy

See prices for flight routes from nearby airports that may be better suited for you.
Charlotte to Heathrow flights
Charlotte to Madrid flights
Charlotte to Munich flights
Charlotte to Frankfurt flights
Charlotte to Dublin flights
Charlotte to Leonardo da Vinci/Fiumicino flights
Charlotte to Charles de Gaulle flights
Charlotte to Gatwick flights
Charlotte to London City flights
Charlotte to Istanbul flights
Charlotte to Orly flights
Charlotte to Lisbon flights
Charlotte to Barcelona-El Prat flights
Charlotte to Edinburgh flights
Charlotte to Malpensa flights
Charlotte to Amsterdam flights
Charlotte to Linate flights
Charlotte to Athens flights
Charleston to Heathrow flights
Savannah to Frankfurt flights
Greenville to Heathrow flights
Charlotte to Sabiha Gokcen flights
Charlotte to Manchester flights
Charleston to Charles de Gaulle flights
Charlotte to Stansted flights
Charlotte to Florence flights
Charlotte to Zurich flights
Charlotte to Glasgow Intl flights
Charlotte to Vicenza flights
Savannah to Charles de Gaulle flights
Charleston to Athens flights
Charleston to Gatwick flights
Charlotte to Prague flights
Charleston to Madrid flights
Charlotte to Keflavik Intl flights
Charlotte to Bruxelles-National flights
Charleston to Dublin flights
Greenville to Charles de Gaulle flights
Savannah to Heathrow flights
Charleston to Orly flights
Charlotte to Oslo Gardermoen flights
Charleston to London City flights
Savannah to Gatwick flights
Charleston to Frankfurt flights
Charlotte to Naples flights
Charleston to Barcelona-El Prat flights
Charlotte to Duesseldorf Intl flights
Charlotte to Bologna flights
Greenville to Barcelona-El Prat flights
Charleston to Amsterdam flights

Top 7 airlines flying from Charleston to Italy

Discover the top 7 airlines that operate flights from Charleston to Italy. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated October 18, 2025.
AirlineCheapestAverageFlexibilityOn-time
United AirlinesCheapest$307Average$992FlexibilityNo cancel feeOn-time69%
KLMCheapest$614Average$1,138FlexibilityNo cancel feeOn-time75%
DeltaCheapest$626Average$1,180FlexibilityNo cancel feeOn-timeN/A
American AirlinesCheapest$628Average$1,200FlexibilityNo cancel feeOn-time71%
British AirwaysCheapest$714Average$1,091FlexibilityNo cancel feeOn-time70%
LufthansaCheapest$743Average$1,217FlexibilityNo cancel feeOn-time76%
Air FranceCheapest$957Average$1,308FlexibilityNo cancel feeOn-time77%

100% Free

Cheapflights is completely free to use, so you can start saving the moment you arrive.

Book with Flexibility

Our users can plan ahead with confidence and find flights with no change fees

Travel Smart

Millions of people come to us for their flight needs every year. We help make travel planning easy by providing useful insights and data-driven graphs that can inform your decisions.