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Istanbul

$475+ Cheap flights from Panama to Istanbul

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 10/6. Fares are subject to change and may not be available on all flights or dates of travel.
PTY — IST
Oct 17 — Oct 241
Fri 10/17
Fri 10/24
1 adult, Economy
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Cheap flight deals from Panama to Istanbul

Keep the following information in mind while searching for Panama to Istanbul flight deals. Data was last updated September 17, 2025.

Round-trip from

$850
(Gotogate)

One-way from

$475
(Kiwi.com)

Popular in

December

Cheapest in

July

Average price

$1,333
From Panama to Istanbul
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One-way flight from Panama to Istanbul
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Highest demand for flights based on searches. 2% potential increase in price ($40 potential increase over avg. RT price).
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Cheapest flight prices on average. 0% potential price decrease ($8 potential savings vs. average RT price).
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Average for round-trip flights in September 2025
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Find flight deals from Panama to Istanbul

Cheapest flights from Panama to Istanbul
Explore the most affordable flight options available from Panama to Istanbul. Find the lowest fares from popular airlines and budget airlines, with prices last updated on September 17, 2025.

This Gotogate deal was found by Cheapflights users on 9/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Gotogate is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 11/79:30 pmPTY - IST
1 stop33h 25mAir Europa
Thu 11/135:15 pmIST - PTY
1 stop34h 30mAir Europa
Deal found 9/16$850
This Air Europa deal was found by Cheapflights users on 9/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Air Europa is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 11/69:30 pmPTY - IST
1 stop33h 25mAir Europa
Sat 11/155:15 pmIST - PTY
1 stop34h 30mAir Europa
Deal found 9/17$877
This FlightHub deal was found by Cheapflights users on 9/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure FlightHub is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 11/109:30 pmPTY - IST
1 stop33h 25mAir Europa
Mon 11/175:15 pmIST - PTY
1 stop34h 30mAir Europa
Deal found 9/16$963
This Air Europa deal was found by Cheapflights users on 9/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Air Europa is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 11/69:30 pmPTY - IST
1 stop33h 25mAir Europa
Sun 11/165:15 pmIST - PTY
1 stop34h 30mAir Europa
Deal found 9/17$984
This Air Europa deal was found by Cheapflights users on 9/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Air Europa is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 10/198:25 pmPTY - IST
1 stop33h 30mAir Europa
Wed 11/125:15 pmIST - PTY
1 stop34h 30mAir Europa
Deal found 9/17$1,012
This Air Europa deal was found by Cheapflights users on 9/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Air Europa is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 11/69:30 pmPTY - IST
1 stop33h 25mAir Europa
Mon 11/105:15 pmIST - PTY
1 stop34h 30mAir Europa
Deal found 9/17$1,023
This Kiwi.com deal was found by Cheapflights users on 9/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 11/76:45 pmPTY - IST
Nonstop12h 45mMultiple Airlines
Thu 11/139:45 pmIST - PTY
3 stops54h 00mMultiple Airlines
Deal found 9/16$1,037
This Air Europa deal was found by Cheapflights users on 9/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Air Europa is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 10/198:25 pmPTY - IST
1 stop33h 30mAir Europa
Mon 11/105:15 pmIST - PTY
1 stop34h 30mAir Europa
Deal found 9/17$1,049
This Trip.com deal was found by Cheapflights users on 9/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Trip.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 11/109:30 pmPTY - IST
2 stops29h 05mMultiple Airlines
Mon 11/176:30 amIST - PTY
2 stops21h 15mMultiple Airlines
Deal found 9/16$1,058
This Kiwi.com deal was found by Cheapflights users on 9/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 10/299:45 pmPTY - IST
Nonstop12h 50mMultiple Airlines
Wed 11/510:00 pmIST - PTY
3 stops53h 45mMultiple Airlines
Deal found 9/17$1,087
This Air Europa deal was found by Cheapflights users on 9/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Air Europa is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 11/69:30 pmPTY - IST
1 stop33h 25mAir Europa
Sun 11/95:15 pmIST - PTY
1 stop34h 30mAir Europa
Deal found 9/17$1,098
This KLM deal was found by Cheapflights users on 9/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure KLM is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 9/226:50 pmPTY - IST
1 stop22h 30mKLM
Sun 9/286:10 amIST - PTY
1 stop18h 40mKLM
Deal found 9/16$1,109

Cheapflights Fare Finder

 
Customize your flight search to find flights from Panama to Istanbul that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated September 17, 2025.
Use the filters below to find and compare flights from Panama to Istanbul that are best for you.

Fly from

Panama

Fly to

Istanbul

Route

Depart

Return

Price

Panama CityIstanbul

PTY - IST

PTYIST

Panama City Tocumen Intl

Mon 11/10

6:45 pm-3:50 am

2 stops25h 05m

Istanbul

Mon 11/17

5:55 pm-4:30 pm

1 stop30h 35m

$1,141

Panama CityIstanbul

PTY - IST

PTYIST

Panama City Tocumen Intl

Fri 11/7

6:45 pm-3:50 am

2 stops25h 05m

Istanbul

Wed 11/12

4:50 am-8:10 pm

1 stop23h 20m

$1,141

Panama CityIstanbul

PTY - IST

PTYIST

Panama City Tocumen Intl

Mon 11/10

6:45 pm-3:50 am

2 stops25h 05m

Istanbul

Sat 11/15

4:50 am-8:10 pm

1 stop23h 20m

$1,141

Panama CityIstanbul

PTY - IST

PTYIST

Panama City Tocumen Intl

Fri 11/7

6:45 pm-3:50 am

2 stops25h 05m

Istanbul

Mon 11/17

4:50 am-4:30 pm

2 stops19h 40m

$1,161

Panama CityIstanbul

PTY - IST

PTYIST

Panama City Tocumen Intl

Mon 11/10

9:30 pm-8:45 pm

1 stop15h 15m

Istanbul

Wed 11/12

5:15 pm-7:45 pm

1 stop34h 30m

$1,273

Panama CityIstanbul

PTY - IST

PTYIST

Panama City Tocumen Intl

Wed 10/29

10:20 pm-3:50 am

1 stop21h 30m

Istanbul

Tue 11/4

4:50 am-4:30 pm

2 stops19h 40m

$1,331

Panama CityIstanbul

PTY - IST

PTYIST

Panama City Tocumen Intl

Thu 10/9

6:50 pm-3:25 am

2 stops24h 35m

Istanbul

Tue 10/14

4:20 am-4:50 pm

2 stops20h 30m

$1,348

Panama CityIstanbul

PTY - IST

PTYIST

Panama City Tocumen Intl

Sun 3/1

10:20 pm-3:50 am

1 stop21h 30m

Istanbul

Fri 3/13

4:50 am-4:30 pm

2 stops19h 40m

$1,390

Panama CityIstanbul

PTY - IST

PTYIST

Panama City Tocumen Intl

Wed 10/1

6:50 pm-4:05 pm

1 stop37h 15m

Istanbul

Wed 10/15

5:05 pm-4:50 pm

1 stop31h 45m

$1,492

Panama CityIstanbul

PTY - IST

PTYIST

Panama City Tocumen Intl

Fri 12/19

6:45 pm-3:30 pm

Nonstop12h 45m

Istanbul

Wed 12/31

8:00 am-5:05 pm

1 stop17h 05m

$1,536

Flights are sorted by cheapest round-trip flights first.

Deals found on 9/17

Showing 1-10 of 18 results
1
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Best time to book a flight from Panama to Istanbul

Have a flexible travel schedule? Discover the best time to fly to Istanbul from Panama with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Panama to Istanbul

What is the cheapest month to book a flight from Panama to Istanbul?

Currently, October is the cheapest month in which you can book a flight from Panama to Istanbul (average of $910). Flying from Panama to Istanbul in June is currently the most expensive (average of $1,358). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

What is the cheapest time of day to fly from PA to IST?

Find hourly flight availability from Panama to Istanbul. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated September 17, 2025.

Unlike in the morning, when flights are generally more expensive, you can save up to 2% on flights from Panama to Istanbul by exploring options for tickets at noon.

Reviews of airlines servicing Istanbul

Get insights into the airlines that provide service to Istanbul. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Istanbul. Reviews last updated September 17, 2025.
See what other customers who have flown with United Airlines, Turkish Airlines, and Air Europa from Panama to Istanbul have to say. You can also see how each airline compares in terms of entertainment options, comfort, food, crew/service, and boarding process.
United Airlines
7.4
Good
8,926 reviews

Boarding

7.7

Crew

8.1

Overall

7.4

Food

6.6

Comfort

7.3

Entertainment

7.1

Reviews

1 / 20
10.0
Excellent

Momny,Jun 2025

HND - BKK

I very love and happy with ANA and Sevice very super good .Thank you ANA
United Airlines
7.4
Good
8,926 reviews
United Airlines
7.4
Good
8,926 reviews

Boarding

7.7

Crew

8.1

Overall

7.4

Food

6.6

Comfort

7.3

Entertainment

7.1

Reviews

1 / 20
10.0
Excellent

Momny,Jun 2025

HND - BKK

I very love and happy with ANA and Sevice very super good .Thank you ANA
Turkish Airlines
7.3
Good
3,965 reviews
United Airlines
7.4
Good
8,926 reviews

Boarding

7.7

Crew

8.1

Overall

7.4

Food

6.6

Comfort

7.3

Entertainment

7.1

Reviews

1 / 20
10.0
Excellent

Momny,Jun 2025

HND - BKK

I very love and happy with ANA and Sevice very super good .Thank you ANA
Air Europa
7.0
Good
557 reviews
United Airlines
7.4
Good
8,926 reviews

Boarding

7.7

Crew

8.1

Overall

7.4

Food

6.6

Comfort

7.3

Entertainment

7.1

Reviews

1 / 20
10.0
Excellent

Momny,Jun 2025

HND - BKK

I very love and happy with ANA and Sevice very super good .Thank you ANA

Related info for your journey

Find useful and relevant information for your journey from Panama to Istanbul. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • How long is the flight from Panama to Istanbul?

    A quick flight from Panama to Istanbul can take about 25h 05m. KLM provides one of the quickest options available for as low as $1,141. The distance from Panama to Istanbul is about 6717 mi.

  • What are the cheapest flights from Panama to Istanbul?

    While on average a flight from Panama to Istanbul is generally $1,427, our data shows the cheapest flight currently is $652. When looking at the most popular route, (Panama City Tocumen Intl - Istanbul), you can expect to pay $1,125 for that flight.

  • Can I find deals for flights from Panama to Istanbul that include hotel bookings?

    Yes. In addition to deals on Panama to Istanbul flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Panama to Istanbul?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Panama to Istanbul.

  • Can I find deals for business class flights from Panama to Istanbul?

    Yes. Cheapflights offers flight deals from Panama to Istanbul by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Panama to Istanbul?

    Currently, October is the cheapest month in which you can book a flight from Panama to Istanbul (average of $910). Flying from Panama to Istanbul in June is currently the most expensive (average of $1,358). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

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Alternative routes for Panama to Istanbul

See prices for flight routes from nearby airports that may be better suited for you.
San José to Istanbul flights
Panama City to Istanbul flights
Guatemala City to Istanbul flights
San Salvador to Istanbul flights

Top 3 airlines flying from Panama to Istanbul

Discover the top 3 airlines that operate flights from Panama to Istanbul. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated September 17, 2025.
AirlineCheapestAverageFlexibilityOn-time
Air EuropaCheapest$892Average$1,066FlexibilityNo cancel feeOn-time83%
United AirlinesCheapest$1,048Average$1,059FlexibilityNo cancel feeOn-time69%
Turkish AirlinesCheapest$1,231Average$1,387FlexibilityNo cancel feeOn-time77%

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