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$483+ Cheap flights from Panama to Istanbul

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 9/29. Fares are subject to change and may not be available on all flights or dates of travel.
PTY — IST
Aug 5 — Aug 121
Tue 8/5
Tue 8/12
1 adult, Economy
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Cheap flight deals from Panama to Istanbul

Keep the following information in mind while searching for Panama to Istanbul flight deals. Data was last updated July 31, 2025.

Round-trip from

$983
(Air France)

One-way from

$483
(Kiwi.com)

Popular in

December

Cheapest in

July

Average price

$1,205
From Panama to Istanbul
Search Deals
One-way flight from Panama to Istanbul
Search Deals
Highest demand for flights based on searches. 2% potential increase in price ($38 potential increase over avg. RT price).
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Cheapest flight prices on average. 0% potential price decrease ($7 potential savings vs. average RT price).
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Average for round-trip flights in July 2025
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Find flight deals from Panama to Istanbul

Cheapest flights from Panama to Istanbul
Explore the most affordable flight options available from Panama to Istanbul. Find the lowest fares from popular airlines and budget airlines, with prices last updated on July 31, 2025.

This Air France deal was found by Cheapflights users on 7/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Air France is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 9/87:55 pmPTY - IST
1 stop23h 30mMultiple Airlines
Wed 9/175:05 pmIST - PTY
1 stop31h 45mMultiple Airlines
Deal found 7/30$983
This Air Europa deal was found by Cheapflights users on 7/31. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Air Europa is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 11/49:30 pmPTY - IST
1 stop33h 25mAir Europa
Thu 11/135:15 pmIST - PTY
1 stop34h 30mAir Europa
Deal found 7/31$993
This KLM deal was found by Cheapflights users on 7/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure KLM is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 9/77:55 pmPTY - IST
2 stops21h 25mKLM
Wed 9/176:10 amIST - PTY
1 stop18h 40mKLM
Deal found 7/30$1,003
This Air France deal was found by Cheapflights users on 7/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Air France is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 8/127:55 pmPTY - IST
1 stop23h 30mAir France
Sun 8/314:20 amIST - PTY
1 stop21h 25mAir France
Deal found 7/29$1,067

Cheapflights Fare Finder

 
Customize your flight search to find flights from Panama to Istanbul that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated July 31, 2025.
Use the filters below to find and compare flights from Panama to Istanbul that are best for you.

Fly from

Panama

Fly to

Istanbul

Route

Depart

Return

Price

Panama CityIstanbul

PTY - IST

PTYIST

Panama City Tocumen Intl

Mon 9/8

7:55 pm-3:25 am

1 stop23h 30m

Istanbul

Wed 9/17

5:05 pm-4:50 pm

1 stop31h 45m

$983

Panama CityIstanbul

PTY - IST

PTYIST

Panama City Tocumen Intl

Tue 11/4

9:30 pm-2:55 pm

1 stop33h 25m

Istanbul

Thu 11/13

5:15 pm-7:45 pm

1 stop34h 30m

$993

Panama CityIstanbul

PTY - IST

PTYIST

Panama City Tocumen Intl

Sun 9/7

7:55 pm-1:20 am

2 stops21h 25m

Istanbul

Wed 9/17

6:10 am-4:50 pm

1 stop18h 40m

$1,003

Panama CityIstanbul

PTY - IST

PTYIST

Panama City Tocumen Intl

Tue 8/12

7:55 pm-3:25 am

1 stop23h 30m

Istanbul

Sun 8/31

4:20 am-5:45 pm

1 stop21h 25m

$1,067

Panama CityIstanbul

PTY - IST

PTYIST

Panama City Tocumen Intl

Mon 9/29

3:25 am-7:25 pm

3 stops32h 00m

$483

Panama CityIstanbul

PTY - IST

PTYIST

Panama City Tocumen Intl

Fri 10/3

9:55 pm-6:40 pm

Nonstop12h 45m

$531

Panama CityIstanbul

PTY - IST

PTYIST

Panama City Tocumen Intl

Mon 8/11

8:25 pm-1:55 pm

1 stop33h 30m

$634

Panama CityIstanbul

PTY - IST

PTYIST

Panama City Tocumen Intl

Sat 10/4

7:55 pm-3:25 am

1 stop23h 30m

$642

Panama CityIstanbul

PTY - IST

PTYIST

Panama City Tocumen Intl

Tue 10/7

7:55 pm-1:20 am

2 stops21h 25m

$661

Panama CityIstanbul

PTY - IST

PTYIST

Panama City Tocumen Intl

Tue 1/6

9:13 am-7:25 pm

2 stops26h 12m

$884

Flights are sorted by cheapest round-trip flights first.

Deals found on 7/30

Showing 1-10 of 11 results
1
2

Best time to book a flight from Panama to Istanbul

Have a flexible travel schedule? Discover the best time to fly to Istanbul from Panama with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Panama to Istanbul

What is the cheapest month to book a flight from Panama to Istanbul?

Currently, November is the cheapest month in which you can book a flight from Panama to Istanbul (average of $923). Flying from Panama to Istanbul in June is currently the most expensive (average of $1,359). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

What is the cheapest time of day to fly from PA to IST?

Find hourly flight availability from Panama to Istanbul. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated July 31, 2025.

Unlike at noon, when flights are generally more expensive, you can save up to 4% on flights from Panama to Istanbul by exploring options for tickets in the morning.

Reviews of airlines servicing Istanbul

Get insights into the airlines that provide service to Istanbul. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Istanbul. Reviews last updated July 31, 2025.
See what other customers who have flown with KLM, Air France, and United Airlines from Panama to Istanbul have to say. You can also see how each airline compares in terms of entertainment options, comfort, food, crew/service, and boarding process.
KLM
7.8
Good
1,383 reviews

Comfort

7.7

Boarding

7.8

Crew

8.4

Entertainment

7.1

Overall

7.8

Food

7.3

Reviews

1 / 20
4.0
Okay

Anonymous,Jun 2025

AMS - BOS

A two and half hour delay caused havoc with all connections. Otherwise on board service was great.
KLM
7.8
Good
1,383 reviews
KLM
7.8
Good
1,383 reviews

Comfort

7.7

Boarding

7.8

Crew

8.4

Entertainment

7.1

Overall

7.8

Food

7.3

Reviews

1 / 20
4.0
Okay

Anonymous,Jun 2025

AMS - BOS

A two and half hour delay caused havoc with all connections. Otherwise on board service was great.
Air France
7.5
Good
1,465 reviews
KLM
7.8
Good
1,383 reviews

Comfort

7.7

Boarding

7.8

Crew

8.4

Entertainment

7.1

Overall

7.8

Food

7.3

Reviews

1 / 20
4.0
Okay

Anonymous,Jun 2025

AMS - BOS

A two and half hour delay caused havoc with all connections. Otherwise on board service was great.
United Airlines
7.4
Good
8,900 reviews
KLM
7.8
Good
1,383 reviews

Comfort

7.7

Boarding

7.8

Crew

8.4

Entertainment

7.1

Overall

7.8

Food

7.3

Reviews

1 / 20
4.0
Okay

Anonymous,Jun 2025

AMS - BOS

A two and half hour delay caused havoc with all connections. Otherwise on board service was great.
Turkish Airlines
7.3
Good
3,933 reviews
KLM
7.8
Good
1,383 reviews

Comfort

7.7

Boarding

7.8

Crew

8.4

Entertainment

7.1

Overall

7.8

Food

7.3

Reviews

1 / 20
4.0
Okay

Anonymous,Jun 2025

AMS - BOS

A two and half hour delay caused havoc with all connections. Otherwise on board service was great.
Air Europa
7.0
Good
543 reviews
KLM
7.8
Good
1,383 reviews

Comfort

7.7

Boarding

7.8

Crew

8.4

Entertainment

7.1

Overall

7.8

Food

7.3

Reviews

1 / 20
4.0
Okay

Anonymous,Jun 2025

AMS - BOS

A two and half hour delay caused havoc with all connections. Otherwise on board service was great.

Related info for your journey

Find useful and relevant information for your journey from Panama to Istanbul. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • What are the cheapest airlines to fly from Panama to Istanbul one-way?

    The cheapest airline one-way is Turkish Airlines, with whom users have recently found tickets for as low as $531. However, be on the lookout for offers from Air Europa and Air France, as they are both options that can get you from Panama to Istanbul for a low price.

  • What are the cheapest flights from Panama to Istanbul?

    While on average a flight from Panama to Istanbul is generally $2,504, our data shows the cheapest flight currently is $478. When looking at the most popular route, (Panama City Tocumen Intl - Istanbul), you can expect to pay $1,070 for that flight.

  • Can I find deals for flights from Panama to Istanbul that include hotel bookings?

    Yes. In addition to deals on Panama to Istanbul flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Panama to Istanbul?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Panama to Istanbul.

  • Can I find deals for business class flights from Panama to Istanbul?

    Yes. Cheapflights offers flight deals from Panama to Istanbul by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Panama to Istanbul?

    Currently, November is the cheapest month in which you can book a flight from Panama to Istanbul (average of $923). Flying from Panama to Istanbul in June is currently the most expensive (average of $1,359). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

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Alternative routes for Panama to Istanbul

See prices for flight routes from nearby airports that may be better suited for you.
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Top 3 airlines flying from Panama to Istanbul

Discover the top 3 airlines that operate flights from Panama to Istanbul. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated July 31, 2025.
AirlineCheapestAverageFlexibilityOn-time
Air EuropaCheapest$892Average$1,091FlexibilityNo cancel feeOn-time83%
United AirlinesCheapest$1,043Average$1,065FlexibilityNo cancel feeOn-time69%
Turkish AirlinesCheapest$1,231Average$1,411FlexibilityNo cancel feeOn-time77%

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