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$574+ Cheap flights from Panama to Istanbul

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 4/28. Fares are subject to change and may not be available on all flights or dates of travel.
PTY — IST
abr. 9 — abr. 161
jue. 4/9
jue. 4/16
1 adult, Economy
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Cheap flight deals from Panama to Istanbul

Cheapest flights from Panama to Istanbul
Explore the most affordable flight options available from Panama to Istanbul. Find the lowest fares from popular airlines and budget airlines, with prices last updated on marzo 10, 2026.

This KLM deal was found by Cheapflights users on 3/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure KLM is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
lun. 4/206:50 pm
PTY
-
IST
1 stop22h 30m
KLM
lun. 4/276:00 am
IST
-
PTY
1 stop18h 50m
KLM
Deal found 3/6$876
This KLM deal was found by Cheapflights users on 3/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure KLM is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
mié. 5/66:50 pm
PTY
-
IST
1 stop22h 30m
KLM
mié. 5/205:20 pm
IST
-
PTY
1 stop31h 30m
KLM
Deal found 3/5$902
This KLM deal was found by Cheapflights users on 3/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure KLM is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
mar. 4/286:50 pm
PTY
-
IST
1 stop22h 30m
KLM
mar. 5/196:00 am
IST
-
PTY
1 stop18h 50m
KLM
Deal found 3/6$906
This KLM deal was found by Cheapflights users on 3/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure KLM is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
mar. 4/216:50 pm
PTY
-
IST
1 stop22h 30m
KLM
mar. 4/286:00 am
IST
-
PTY
1 stop18h 50m
KLM
Deal found 3/6$938
This KLM deal was found by Cheapflights users on 3/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure KLM is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
dom. 5/179:55 pm
PTY
-
IST
2 stops19h 25m
KLM
mié. 5/274:25 am
IST
-
PTY
2 stops20h 25m
KLM
Deal found 3/5$942
This KLM deal was found by Cheapflights users on 3/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure KLM is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
vie. 5/156:50 pm
PTY
-
IST
1 stop22h 30m
KLM
sáb. 5/306:00 am
IST
-
PTY
1 stop18h 50m
KLM
Deal found 3/9$962
This Air France deal was found by Cheapflights users on 3/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Air France is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
lun. 4/139:55 pm
PTY
-
IST
1 stop21h 35m
Multiple Airlines
sáb. 4/255:20 pm
IST
-
PTY
1 stop31h 30m
Multiple Airlines
Deal found 3/9$963
This KLM deal was found by Cheapflights users on 3/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure KLM is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
mié. 5/206:50 pm
PTY
-
IST
1 stop22h 30m
KLM
sáb. 6/65:20 pm
IST
-
PTY
1 stop31h 30m
KLM
Deal found 3/6$964

Find flight deals from Panama to Istanbul

Keep the following information in mind while searching for Panama to Istanbul flight deals. Data was last updated marzo 10, 2026.

Round-trip from

$876
(KLM)

One-way from

$574
(Kiwi.com)

Popular in

December

Cheapest in

May

Average price

$1,191
From Panama to Istanbul
Search Deals
One-way flight from Panama to Istanbul
Search Deals
Highest demand for flights based on searches. 3% potential increase in price ($38 potential increase over avg. RT price).
Search Deals
Cheapest flight prices on average. 0% potential price decrease ($9 potential savings vs. average RT price).
Search Deals
Average for round-trip flights in March 2026
Search Deals

Cheapflights Fare Finder

 
Customize your flight search to find flights from Panama to Istanbul that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated marzo 10, 2026.
Use the filters below to find and compare flights from Panama to Istanbul that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

Cheapest round-trip

Panama CityIstanbul

PTY - IST

PTYIST

Panama City Tocumen Intl

lun. 4/20

6:50 pm-1:20 am

1 stop22h 30m

Istanbul

lun. 4/27

6:00 am-4:50 pm

1 stop18h 50m

$876

Panama CityIstanbul

PTY - IST

PTYIST

Panama City Tocumen Intl

mar. 5/5

6:50 pm-1:20 am

1 stop22h 30m

Istanbul

mié. 5/20

4:25 am-4:50 pm

2 stops20h 25m

$993

Panama CityIstanbul

PTY - IST

PTYIST

Panama City Tocumen Intl

mar. 4/21

6:50 pm-4:20 pm

1 stop37h 30m

Istanbul

mar. 4/28

6:00 am-7:45 pm

2 stops21h 45m

$995
Quickest round-trip

Panama CityIstanbul

PTY - IST

PTYIST

Panama City Tocumen Intl

lun. 3/30

9:55 pm-1:20 am

2 stops19h 25m

Istanbul

lun. 4/13

4:25 am-4:50 pm

2 stops20h 25m

$1,101

Panama CityIstanbul

PTY - IST

PTYIST

Panama City Tocumen Intl

lun. 8/3

8:25 pm-1:55 pm

1 stop33h 30m

Istanbul

dom. 8/16

3:45 pm-6:40 pm

1 stop34h 55m

$1,114

Panama CityIstanbul

PTY - IST

PTYIST

Panama City Tocumen Intl

jue. 5/28

6:50 pm-1:20 am

1 stop22h 30m

Istanbul

lun. 6/8

6:00 am-7:45 pm

2 stops21h 45m

$1,130

Panama CityIstanbul

PTY - IST

PTYIST

Panama City Tocumen Intl

dom. 5/3

9:55 pm-1:20 am

2 stops19h 25m

Istanbul

mié. 5/13

4:25 am-4:50 pm

2 stops20h 25m

$1,140

Panama CityIstanbul

PTY - IST

PTYIST

Panama City Tocumen Intl

dom. 6/14

6:50 pm-1:20 am

1 stop22h 30m

Istanbul

lun. 6/29

5:20 pm-4:50 pm

1 stop31h 30m

$1,143
Cheapest one-way

Panama CityIstanbul

PTY - IST

PTYIST

Panama City Tocumen Intl

mar. 4/28

8:25 pm-12:15 pm

3 stops31h 50m

$574

Panama CityIstanbul

PTY - IST

PTYIST

Panama City Tocumen Intl

dom. 3/29

7:25 pm-4:10 pm

2 stops36h 45m

$648

Flights are sorted by cheapest round-trip flights first.

Deals found on 3/6

Showing 1-10 of 17 resultsSorted by cheapest first
1
2

Best time to book a flight from Panama to Istanbul

Have a flexible travel schedule? Discover the best time to fly to Istanbul from Panama with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Panama to Istanbul

What is the cheapest month to book a flight from Panama to Istanbul?

Currently, October is the cheapest month in which you can book a flight from Panama to Istanbul (average of $875). Flying from Panama to Istanbul in August is currently the most expensive (average of $1,096). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

What is the cheapest time of day to fly from PA to IST?

Find hourly flight availability from Panama to Istanbul. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated marzo 10, 2026.

Regardless of the time of day you decide to fly, the ticket price will remain around the same. Book flights from Panama to Istanbul as you normally would.

How often are flights from Panama to Istanbul delayed?

About 22% of weekly flights between Panama and Istanbul have experienced delays in the past year, with the average delay time being 147 minutes.

What is the most punctual flight time for Panama to Istanbul flights?

Historically, flights departing at night are less likely to be delayed, whereas flights leaving in the evening tend to experience delays more often.

What day of the week experiences the fewest flight delays on this route?

Friday tends to have the lowest number of delays on this route, whereas Tuesday has historically faced a higher average of delays compared to other days of the week.

Which airline has the best punctuality record on Panama to Istanbul flights?

Over the last year, Turkish Airlines have had the lowest number of delays on this route, with just 22% of flights being delayed.

Reviews of airlines servicing Istanbul

Get insights into the airlines that provide service to Istanbul. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Istanbul. Reviews last updated marzo 10, 2026.
See what other customers who have flown with Turkish Airlines and Air Europa from Panama to Istanbul have to say. You can also see how each airline compares in terms of entertainment options, comfort, food, crew/service, and boarding process.
Turkish Airlines
7.3
Good
4,249 reviews

Crew

7.8

Entertainment

7.5

Food

7.5

Boarding

7.3

Comfort

7.3

Overall

7.3

Reviews

1 / 20
6.0
Good

Anonymous,Jan 2026

NQZ - IST

First of all, my flight got delayed. When I had a registration in Astana, the girl who was working on a desk was too lazy to fill out my info and that’s why she gave me only 2 tickets instead of 3. While boarding I realized it and had to talk to another worker who was solving this problem. My seat was near emergency door, people in front were reclining their seats, but I couldn’t- that made me have a little space to sit, move, etc. That was really uncomfortable. So the flight itself also took longer and I didn’t have time to reach another gate for next flight, even tho flight attendant said plane will be in time. I had to go to Turkish Airlines main office, most of workers didn’t speak enough good English to explain properly where it is. It also took me like 1,5 hours to solve. I was not satisfied with the flight at all this time.
Turkish Airlines
7.3
Good
4,249 reviews
Turkish Airlines
7.3
Good
4,249 reviews

Crew

7.8

Entertainment

7.5

Food

7.5

Boarding

7.3

Comfort

7.3

Overall

7.3

Reviews

1 / 20
6.0
Good

Anonymous,Jan 2026

NQZ - IST

First of all, my flight got delayed. When I had a registration in Astana, the girl who was working on a desk was too lazy to fill out my info and that’s why she gave me only 2 tickets instead of 3. While boarding I realized it and had to talk to another worker who was solving this problem. My seat was near emergency door, people in front were reclining their seats, but I couldn’t- that made me have a little space to sit, move, etc. That was really uncomfortable. So the flight itself also took longer and I didn’t have time to reach another gate for next flight, even tho flight attendant said plane will be in time. I had to go to Turkish Airlines main office, most of workers didn’t speak enough good English to explain properly where it is. It also took me like 1,5 hours to solve. I was not satisfied with the flight at all this time.
Air Europa
6.9
Okay
593 reviews
Turkish Airlines
7.3
Good
4,249 reviews

Crew

7.8

Entertainment

7.5

Food

7.5

Boarding

7.3

Comfort

7.3

Overall

7.3

Reviews

1 / 20
6.0
Good

Anonymous,Jan 2026

NQZ - IST

First of all, my flight got delayed. When I had a registration in Astana, the girl who was working on a desk was too lazy to fill out my info and that’s why she gave me only 2 tickets instead of 3. While boarding I realized it and had to talk to another worker who was solving this problem. My seat was near emergency door, people in front were reclining their seats, but I couldn’t- that made me have a little space to sit, move, etc. That was really uncomfortable. So the flight itself also took longer and I didn’t have time to reach another gate for next flight, even tho flight attendant said plane will be in time. I had to go to Turkish Airlines main office, most of workers didn’t speak enough good English to explain properly where it is. It also took me like 1,5 hours to solve. I was not satisfied with the flight at all this time.

Related info for your journey

Find useful and relevant information for your journey from Panama to Istanbul. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • How long is the flight from Panama to Istanbul?

    A quick flight from Panama to Istanbul can take about 22h 30m. KLM provides one of the quickest options available for as low as $876. The distance from Panama to Istanbul is about 6717 mi.

  • What are the cheapest flights from Panama to Istanbul?

    While on average a flight from Panama to Istanbul is generally $1,226, our data shows the cheapest flight currently is $752. When looking at the most popular route, (Panama City Tocumen Intl - Istanbul), you can expect to pay $1,067 for that flight.

  • Can I find deals for flights from Panama to Istanbul that include hotel bookings?

    Yes. In addition to deals on Panama to Istanbul flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Panama to Istanbul?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Panama to Istanbul.

  • Can I find deals for business class flights from Panama to Istanbul?

    Yes. Cheapflights offers flight deals from Panama to Istanbul by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Panama to Istanbul?

    Currently, October is the cheapest month in which you can book a flight from Panama to Istanbul (average of $875). Flying from Panama to Istanbul in August is currently the most expensive (average of $1,096). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

Browse thousands of different options on Cheapflights for your next trip

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Top 2 airlines flying from Panama to Istanbul

Discover the top 2 airlines that operate flights from Panama to Istanbul. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated marzo 10, 2026.
AirlineCheapestAverageFlexibilityOn-time
Air EuropaCheapest$877Average$1,066FlexibilityNo cancel feeOn-time83%
Turkish AirlinesCheapest$1,197Average$1,354FlexibilityNo cancel feeOn-time77%

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