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$558+ Cheap flights from Panama to Istanbul

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 5/4. Fares are subject to change and may not be available on all flights or dates of travel.
PTY — IST
ene. 22 — ene. 291
jue. 1/22
jue. 1/29
1 adult, Economy
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Cheap flight deals from Panama to Istanbul

Cheapest flights from Panama to Istanbul
Explore the most affordable flight options available from Panama to Istanbul. Find the lowest fares from popular airlines and budget airlines, with prices last updated on diciembre 23, 2025.

This KLM deal was found by Cheapflights users on 12/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure KLM is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
jue. 12/256:45 pmPTY - IST
2 stops25h 05mKLM
sáb. 1/35:55 pmIST - PTY
2 stops34h 15mKLM
Deal found 12/23$1,290
This Air France deal was found by Cheapflights users on 12/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Air France is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
mié. 12/3110:20 pmPTY - IST
1 stop21h 30mMultiple Airlines
mar. 1/135:55 pmIST - PTY
2 stops34h 15mMultiple Airlines
Deal found 12/23$1,309
This Air France deal was found by Cheapflights users on 12/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Air France is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
jue. 12/256:45 pmPTY - IST
2 stops25h 05mMultiple Airlines
sáb. 1/35:55 pmIST - PTY
2 stops34h 15mMultiple Airlines
Deal found 12/22$1,352
This Air France deal was found by Cheapflights users on 12/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Air France is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
vie. 12/2610:20 pmPTY - IST
1 stop21h 30mMultiple Airlines
sáb. 1/105:55 pmIST - PTY
2 stops34h 15mMultiple Airlines
Deal found 12/21$1,620

Find flight deals from Panama to Istanbul

Keep the following information in mind while searching for Panama to Istanbul flight deals. Data was last updated diciembre 23, 2025.

Round-trip from

$965
(KLM)

One-way from

$558
(Kiwi.com)

Popular in

December

Cheapest in

July

Average price

$1,375
From Panama to Istanbul
Search Deals
One-way flight from Panama to Istanbul
Search Deals
Highest demand for flights based on searches. 2% potential increase in price ($30 potential increase over avg. RT price).
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Cheapest flight prices on average. 0% potential price decrease ($7 potential savings vs. average RT price).
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Average for round-trip flights in December 2025
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Cheapflights Fare Finder

 
Customize your flight search to find flights from Panama to Istanbul that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated diciembre 23, 2025.
Use the filters below to find and compare flights from Panama to Istanbul that are best for you.

Fly from

Panama

Fly to

Istanbul

Route

Depart

Return

Price

Panama CityIstanbul

PTY - IST

PTYIST

Panama City Tocumen Intl

dom. 5/10

6:50 pm-1:20 am

1 stop22h 30m

Istanbul

mié. 5/20

6:00 am-4:50 pm

1 stop18h 50m

$965

Panama CityIstanbul

PTY - IST

PTYIST

Panama City Tocumen Intl

sáb. 2/7

10:05 pm-4:55 pm

1 stop34h 50m

Istanbul

mar. 3/31

4:25 am-4:50 pm

2 stops20h 25m

$986

Panama CityIstanbul

PTY - IST

PTYIST

Panama City Tocumen Intl

mié. 5/27

6:50 pm-1:20 am

1 stop22h 30m

Istanbul

mar. 6/9

5:20 pm-4:50 pm

1 stop31h 30m

$1,001

Panama CityIstanbul

PTY - IST

PTYIST

Panama City Tocumen Intl

dom. 2/15

6:45 pm-3:50 am

2 stops25h 05m

Istanbul

mar. 2/24

4:50 am-8:10 pm

1 stop23h 20m

$1,021

Panama CityIstanbul

PTY - IST

PTYIST

Panama City Tocumen Intl

mar. 4/21

8:25 pm-1:55 pm

1 stop33h 30m

Istanbul

lun. 5/4

3:45 pm-6:40 pm

1 stop34h 55m

$1,032

Panama CityIstanbul

PTY - IST

PTYIST

Panama City Tocumen Intl

dom. 2/15

6:45 pm-3:50 am

2 stops25h 05m

Istanbul

mar. 2/24

4:50 am-7:55 pm

2 stops23h 05m

$1,041

Panama CityIstanbul

PTY - IST

PTYIST

Panama City Tocumen Intl

lun. 2/9

9:30 pm-2:55 pm

1 stop33h 25m

Istanbul

dom. 2/15

5:15 pm-7:45 pm

1 stop34h 30m

$1,069

Panama CityIstanbul

PTY - IST

PTYIST

Panama City Tocumen Intl

lun. 5/4

8:10 pm-7:35 pm

3 stops39h 25m

$558

Panama CityIstanbul

PTY - IST

PTYIST

Panama City Tocumen Intl

mar. 2/10

6:31 pm-10:45 pm

2 stops20h 14m

$603

Panama CityIstanbul

PTY - IST

PTYIST

Panama City Tocumen Intl

lun. 5/4

6:28 pm-9:15 pm

2 stops42h 47m

$638

Flights are sorted by cheapest round-trip flights first.

Deals found on 12/22

Showing 1-10 of 18 results
1
2

Best time to book a flight from Panama to Istanbul

Have a flexible travel schedule? Discover the best time to fly to Istanbul from Panama with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Panama to Istanbul

What is the cheapest month to book a flight from Panama to Istanbul?

Currently, July is the cheapest month in which you can book a flight from Panama to Istanbul (average of $916). Flying from Panama to Istanbul in August is currently the most expensive (average of $1,099). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

What is the cheapest time of day to fly from PA to IST?

Find hourly flight availability from Panama to Istanbul. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated diciembre 23, 2025.

Regardless of the time of day you decide to fly, the ticket price will remain around the same. Book flights from Panama to Istanbul as you normally would.

How often are flights from Panama to Istanbul delayed?

About 18% of weekly flights between Panama and Istanbul have experienced delays in the past year, with the average delay time being 133 minutes.

What is the most punctual flight time for Panama to Istanbul flights?

Historically, flights departing at night are less likely to be delayed, whereas flights leaving in the evening tend to experience delays more often.

What day of the week experiences the fewest flight delays on this route?

Friday tends to have the lowest number of delays on this route, whereas Tuesday has historically faced a higher average of delays compared to other days of the week.

Which airline has the best punctuality record on Panama to Istanbul flights?

Over the last year, Turkish Airlines have had the lowest number of delays on this route, with just 18% of flights being delayed.

Reviews of airlines servicing Istanbul

Get insights into the airlines that provide service to Istanbul. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Istanbul. Reviews last updated diciembre 23, 2025.
See what other customers who have flown with Turkish Airlines and Air Europa from Panama to Istanbul have to say. You can also see how each airline compares in terms of entertainment options, comfort, food, crew/service, and boarding process.
Turkish Airlines
7.3
Good
4,112 reviews

Entertainment

7.4

Overall

7.3

Boarding

7.3

Food

7.4

Crew

7.8

Comfort

7.3

Reviews

1 / 20
6.0
Good

Chandra,Nov 2025

ATL - IST

TV was not available in Indigo from Istanbul to Delhi. Seat was not moving back. It was jammed.
Turkish Airlines
7.3
Good
4,112 reviews
Turkish Airlines
7.3
Good
4,112 reviews

Entertainment

7.4

Overall

7.3

Boarding

7.3

Food

7.4

Crew

7.8

Comfort

7.3

Reviews

1 / 20
6.0
Good

Chandra,Nov 2025

ATL - IST

TV was not available in Indigo from Istanbul to Delhi. Seat was not moving back. It was jammed.
Air Europa
7.0
Good
574 reviews
Turkish Airlines
7.3
Good
4,112 reviews

Entertainment

7.4

Overall

7.3

Boarding

7.3

Food

7.4

Crew

7.8

Comfort

7.3

Reviews

1 / 20
6.0
Good

Chandra,Nov 2025

ATL - IST

TV was not available in Indigo from Istanbul to Delhi. Seat was not moving back. It was jammed.

Related info for your journey

Find useful and relevant information for your journey from Panama to Istanbul. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • How long is the flight from Panama to Istanbul?

    A quick flight from Panama to Istanbul can take about 22h 30m. KLM provides one of the quickest options available for as low as $965. The distance from Panama to Istanbul is about 6717 mi.

  • What are the cheapest flights from Panama to Istanbul?

    While on average a flight from Panama to Istanbul is generally $1,343, our data shows the cheapest flight currently is $744. When looking at the most popular route, (Panama City Tocumen Intl - Istanbul), you can expect to pay $1,512 for that flight.

  • Can I find deals for flights from Panama to Istanbul that include hotel bookings?

    Yes. In addition to deals on Panama to Istanbul flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Panama to Istanbul?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Panama to Istanbul.

  • Can I find deals for business class flights from Panama to Istanbul?

    Yes. Cheapflights offers flight deals from Panama to Istanbul by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Panama to Istanbul?

    Currently, July is the cheapest month in which you can book a flight from Panama to Istanbul (average of $916). Flying from Panama to Istanbul in August is currently the most expensive (average of $1,099). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

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Alternative routes for Panama to Istanbul

See prices for flight routes from nearby airports that may be better suited for you.
San José to Istanbul flights
Panama City to Istanbul flights
San Salvador to Istanbul flights
Guatemala City to Istanbul flights

Top 2 airlines flying from Panama to Istanbul

Discover the top 2 airlines that operate flights from Panama to Istanbul. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated diciembre 23, 2025.
AirlineCheapestAverageFlexibilityOn-time
Air EuropaCheapest$892Average$1,066FlexibilityNo cancel feeOn-time83%
Turkish AirlinesCheapest$1,224Average$1,380FlexibilityNo cancel feeOn-time77%

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