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$642+ Cheap flights from Panama to Istanbul

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 7/1. Fares are subject to change and may not be available on all flights or dates of travel.
PTY — IST
Jun 21 — Jun 281
Sat 6/21
Sat 6/28
1 adult, Economy
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Cheap flight deals from Panama to Istanbul

Keep the following information in mind while searching for Panama to Istanbul flight deals. Data was last updated June 16, 2025.

Round-trip from

$991
(Air Europa)

One-way from

$642
(Air France)

Popular in

February

Cheapest in

July

Average price

$1,332
From Panama to Istanbul
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One-way flight from Panama to Istanbul
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Highest demand for flights based on searches. 4% potential increase in price ($62 potential increase over avg. RT price).
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Cheapest flight prices on average. 0% potential price decrease ($9 potential savings vs. average RT price).
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Average for round-trip flights in June 2025
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Find flight deals from Panama to Istanbul

Cheapest flights from Panama to Istanbul
Explore the most affordable flight options available from Panama to Istanbul. Find the lowest fares from popular airlines and budget airlines, with prices last updated on June 16, 2025.

This Air Europa deal was found by Cheapflights users on 6/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Air Europa is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 10/58:25 pmPTY - IST
1 stop33h 30mAir Europa
Sat 10/183:45 pmIST - PTY
1 stop34h 55mAir Europa
Deal found 6/14$991
This FlightHub deal was found by Cheapflights users on 6/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure FlightHub is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/248:25 pmPTY - IST
1 stop34h 30mMultiple Airlines
Fri 11/144:45 pmIST - PTY
1 stop35h 00mMultiple Airlines
Deal found 6/14$1,147
This Turkish Airlines deal was found by Cheapflights users on 6/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Turkish Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 7/309:55 pmPTY - IST
Nonstop12h 45mTurkish Airlines
Wed 8/62:10 pmIST - PTY
Nonstop13h 50mTurkish Airlines
Deal found 6/15$1,300
This United Airlines deal was found by Cheapflights users on 6/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 10/510:29 pmPTY - IST
2 stops36h 26mUnited Airlines
Tue 10/1410:10 amIST - PTY
2 stops28h 03mUnited Airlines
Deal found 6/14$1,367
This Air France deal was found by Cheapflights users on 6/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Air France is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 9/67:55 pmPTY - IST
1 stop23h 30mAir France
Sat 9/204:20 amIST - PTY
1 stop21h 25mAir France
Deal found 6/15$1,369
This Air France deal was found by Cheapflights users on 6/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Air France is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 10/16:50 pmPTY - IST
1 stop37h 30mKLM
Wed 10/155:05 pmIST - PTY
2 stops32h 40mKLM
Deal found 6/14$1,621

Cheapflights Fare Finder

Customize your flight search to find flights from Panama to Istanbul that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated June 16, 2025.
Use the filters below to find and compare flights from Panama to Istanbul that are best for you.

Fly from

Panama

Fly to

Istanbul

Route

Depart

Return

Price

Panama CityIstanbul

PTY - IST

PTYIST

Panama City Tocumen Intl

Sun 10/5

8:25 pm-1:55 pm

1 stop33h 30m

Istanbul

Sat 10/18

3:45 pm-6:40 pm

1 stop34h 55m

$991

Panama CityIstanbul

PTY - IST

PTYIST

Panama City Tocumen Intl

Fri 10/24

8:25 pm-2:55 pm

1 stop34h 30m

Istanbul

Fri 11/14

4:45 pm-7:45 pm

1 stop35h 00m

$1,147

Panama CityIstanbul

PTY - IST

PTYIST

Panama City Tocumen Intl

Wed 7/30

9:55 pm-6:40 pm

Nonstop12h 45m

Istanbul

Wed 8/6

2:10 pm-8:00 pm

Nonstop13h 50m

$1,300

Panama CityIstanbul

PTY - IST

PTYIST

Panama City Tocumen Intl

Sun 10/5

10:29 pm-4:20 pm

2 stops33h 51m

Istanbul

Fri 10/17

7:15 am-6:13 am

2 stops30h 58m

$1,367

Panama CityIstanbul

PTY - IST

PTYIST

Panama City Tocumen Intl

Sat 9/6

7:55 pm-3:25 am

1 stop23h 30m

Istanbul

Sat 9/20

4:20 am-5:45 pm

1 stop21h 25m

$1,369

Panama CityIstanbul

PTY - IST

PTYIST

Panama City Tocumen Intl

Wed 10/1

6:50 pm-4:20 pm

1 stop37h 30m

Istanbul

Wed 10/15

5:05 pm-5:45 pm

2 stops32h 40m

$1,621

Panama CityIstanbul

PTY - IST

PTYIST

Panama City Tocumen Intl

Tue 7/1

7:55 pm-3:25 am

1 stop23h 30m

$642

Panama CityIstanbul

PTY - IST

PTYIST

Panama City Tocumen Intl

Tue 7/1

11:20 am-3:50 am

3 stops56h 30m

$643

Panama CityIstanbul

PTY - IST

PTYIST

Panama City Tocumen Intl

Sat 6/28

12:04 pm-11:00 pm

2 stops26h 56m

$748

Panama CityIstanbul

PTY - IST

PTYIST

Panama City Tocumen Intl

Fri 10/3

8:25 pm-1:55 pm

1 stop33h 30m

$796

Flights are sorted by cheapest round-trip flights first.

Deals found on 6/15

Showing 1-10 of 13 results
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Best time to book a flight from Panama to Istanbul

Have a flexible travel schedule? Discover the best time to fly to Istanbul from Panama with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Panama to Istanbul

What is the cheapest month to book a flight from Panama to Istanbul?

Currently, November is the cheapest month in which you can book a flight from Panama to Istanbul (average of $923). Flying from Panama to Istanbul in June is currently the most expensive (average of $1,374). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

What is the cheapest time of day to fly from PA to IST?

Find hourly flight availability from Panama to Istanbul. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated June 16, 2025.

Unlike at noon, when flights are generally more expensive, you can save up to 6% on flights from Panama to Istanbul by exploring options for tickets in the morning.

Rainfall in Istanbul by month

Plan your trip to Istanbul by taking into account the average rainfall totals by month.

In terms of precipitation, rainfall in Istanbul ranges from 0.4 - 3.9 inches per month. December is typically the wettest month, when rainfall can reach 3.9 in. July is typically the driest time to visit Istanbul when rainfall is around 0.4 in.

Temperature in Istanbul by month

Plan your trip to Istanbul by taking into account the average temperature totals by month.

If weather is an important factor for your trip to Istanbul, use this chart to help with planning. For those seeking warmer temperatures, July is the ideal time of year to visit, when temperatures reach an average of 73.4 F. Travelers looking to avoid the cold should look outside of January, when temperatures are typically at their lowest (around 41.0 F).

Reviews of airlines servicing Istanbul

Get insights into the airlines that provide service to Istanbul. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Istanbul. Reviews last updated June 16, 2025.
To help decide which airline to fly from Panama to Istanbul, see what other customers have to say about KLM, Air France and Qatar Airways. You can also see how each airline compares in terms of entertainment options, comfort, food, crew/service, and boarding process.
KLM
7.8
Good
1,361 reviews

Crew

8.4

Comfort

7.7

Boarding

7.8

Entertainment

7.1

Overall

7.8

Food

7.2

Reviews

1 / 20
4.0
Okay

Anonymous,Jun 2025

AMS - BOS

A two and half hour delay caused havoc with all connections. Otherwise on board service was great.
KLM
7.8
Good
1,361 reviews
KLM
7.8
Good
1,361 reviews

Crew

8.4

Comfort

7.7

Boarding

7.8

Entertainment

7.1

Overall

7.8

Food

7.2

Reviews

1 / 20
4.0
Okay

Anonymous,Jun 2025

AMS - BOS

A two and half hour delay caused havoc with all connections. Otherwise on board service was great.
Air France
7.5
Good
1,466 reviews
KLM
7.8
Good
1,361 reviews

Crew

8.4

Comfort

7.7

Boarding

7.8

Entertainment

7.1

Overall

7.8

Food

7.2

Reviews

1 / 20
4.0
Okay

Anonymous,Jun 2025

AMS - BOS

A two and half hour delay caused havoc with all connections. Otherwise on board service was great.
Qatar Airways
7.4
Good
3,591 reviews
KLM
7.8
Good
1,361 reviews

Crew

8.4

Comfort

7.7

Boarding

7.8

Entertainment

7.1

Overall

7.8

Food

7.2

Reviews

1 / 20
4.0
Okay

Anonymous,Jun 2025

AMS - BOS

A two and half hour delay caused havoc with all connections. Otherwise on board service was great.
United Airlines
7.4
Good
8,801 reviews
KLM
7.8
Good
1,361 reviews

Crew

8.4

Comfort

7.7

Boarding

7.8

Entertainment

7.1

Overall

7.8

Food

7.2

Reviews

1 / 20
4.0
Okay

Anonymous,Jun 2025

AMS - BOS

A two and half hour delay caused havoc with all connections. Otherwise on board service was great.
Turkish Airlines
7.3
Good
3,852 reviews
KLM
7.8
Good
1,361 reviews

Crew

8.4

Comfort

7.7

Boarding

7.8

Entertainment

7.1

Overall

7.8

Food

7.2

Reviews

1 / 20
4.0
Okay

Anonymous,Jun 2025

AMS - BOS

A two and half hour delay caused havoc with all connections. Otherwise on board service was great.

Related info for your journey

Find useful and relevant information for your journey from Panama to Istanbul. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • What are the cheapest airlines to fly from Panama to Istanbul one-way?

    The cheapest airline one-way is Air France, with whom users have recently found tickets for as low as $642. However, be on the lookout for offers from United Airlines and Air Europa, as they are both options that can get you from Panama to Istanbul for a low price.

  • What are the cheapest flights from Panama to Istanbul?

    While on average a flight from Panama to Istanbul is generally $1,145, our data shows the cheapest flight currently is $434. When looking at the most popular route, (Panama City Tocumen Intl - Istanbul), you can expect to pay $1,372 for that flight.

  • Can I find deals for flights from Panama to Istanbul that include hotel bookings?

    Yes. In addition to deals on Panama to Istanbul flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Panama to Istanbul?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Panama to Istanbul.

  • Can I find deals for business class flights from Panama to Istanbul?

    Yes. Cheapflights offers flight deals from Panama to Istanbul by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Panama to Istanbul?

    Currently, November is the cheapest month in which you can book a flight from Panama to Istanbul (average of $923). Flying from Panama to Istanbul in June is currently the most expensive (average of $1,374). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

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Alternative routes for Panama to Istanbul

See prices for flight routes from nearby airports that may be better suited for you.
San José to Istanbul flights
San Salvador to Istanbul flights
Guatemala City to Istanbul flights
Panama City to Istanbul flights

Top 3 airlines flying from Panama to Istanbul

Discover the top 3 airlines that operate flights from Panama to Istanbul. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated June 16, 2025.
AirlineCheapestAverageFlexibilityOn-time
Air EuropaCheapest$892Average$1,066FlexibilityNo cancel feeOn-time83%
United AirlinesCheapest$1,043Average$1,065FlexibilityNo cancel feeOn-time69%
Turkish AirlinesCheapest$1,231Average$1,461FlexibilityNo cancel feeOn-time77%

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