HomeSearch by dateVacation packagesHotelsFlight dealsCar rentalTravel tips & news
Istanbul

$403+ Cheap flights from Knoxville (TYS) to Istanbul

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 3/25. Fares are subject to change and may not be available on all flights or dates of travel.
TYS — IST
dic. 26 — ene. 21
vie. 12/26
vie. 1/2
1 adult, Economy
We work with more than 300 partners to bring you better travel deals

Find cheap flights from Knoxville to Istanbul with Cheapflights

1. Tell us where you want to go

Enter your travel information like dates, passengers, trip type (one-way or round trip), and preferred cabin class then click “Find deals”

2. Select your favorite providers

We find the providers serving your travel needs. Choose up to four travel providers to compare side-by-side for flights, hotels, or car rentals.

3. Compare prices and book

Review each provider’s pricing and select the best option for you! Book through your favorite provider’s website for a seamless experience.

Cheap flight deals from Knoxville to Istanbul

Discover tips and strategies to find the most affordable flight options for your journey from Knoxville (TYS) to Istanbul (TR5). Learn about various techniques such as flexible date searches, comparing prices across and setting up price alerts. Use these methods to find the cheapest flights available for your travel needs. Data last updated noviembre 26, 2025.

Round-trip from

$562
(FlightHub)

One-way from

$403
(Kiwi.com)

Popular in

June

Cheapest in

February

Average price

$770
From Knoxville McGhee Tyson to Istanbul
Search Deals
One-way flight from Knoxville McGhee Tyson to Istanbul
Search Deals
Highest demand for flights based on searches. 22% potential increase in price ($310 potential increase over avg. RT price).
Search Deals
Cheapest flight prices on average. 3% potential price decrease ($39 potential savings vs. average RT price).
Search Deals
Average for round-trip flights in November 2025
Search Deals

Find flight deals from Knoxville to Istanbul

Best flights from Knoxville to Istanbul
Discover carefully curated flight deals from Knoxville to Istanbul that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated noviembre 26, 2025.

This FlightHub deal was found by Cheapflights users on 11/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure FlightHub is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
lun. 1/195:29 pmTYS - IST
2 stops40h 16mLufthansa
mar. 2/36:30 amIST - TYS
2 stops22h 22mLufthansa
Deal found 11/25$562
This oojo deal was found by Cheapflights users on 11/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure oojo is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
vie. 1/162:19 pmTYS - IST
2 stops19h 06mBritish Airways
vie. 1/308:10 amIST - TYS
2 stops20h 46mBritish Airways
Deal found 11/25$564
This United Airlines deal was found by Cheapflights users on 11/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
vie. 1/237:20 pmTYS - IST
2 stops14h 45mUnited Airlines
mar. 1/276:30 amIST - TYS
2 stops20h 57mUnited Airlines
Deal found 11/25$572
This Delta deal was found by Cheapflights users on 11/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
lun. 1/191:00 pmTYS - IST
2 stops30h 50mDelta
lun. 2/24:50 amIST - TYS
2 stops26h 55mDelta
Deal found 11/25$599
This Lufthansa deal was found by Cheapflights users on 11/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Lufthansa is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
vie. 1/232:25 pmTYS - IST
2 stops19h 40mLufthansa
mar. 1/276:30 amIST - TYS
2 stops22h 22mLufthansa
Deal found 11/23$572
This KLM deal was found by Cheapflights users on 11/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure KLM is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
lun. 1/191:00 pmTYS - SAW
2 stops20h 25mKLM
mar. 2/39:00 amSAW - TYS
2 stops19h 47mKLM
Deal found 11/25$1,241
This Kiwi.com deal was found by Cheapflights users on 11/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
lun. 1/197:15 amTYS - IST
1 stop26h 55mMultiple Airlines
mar. 2/33:20 pmIST - TYS
2 stops49h 19mMultiple Airlines
Deal found 11/25$1,268
This Delta deal was found by Cheapflights users on 11/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
vie. 1/166:09 pmTYS - IST
2 stops25h 41mDelta
jue. 1/294:50 amIST - TYS
2 stops23h 57mDelta
Deal found 11/25$661
This Delta deal was found by Cheapflights users on 11/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
vie. 1/231:00 pmTYS - IST
2 stops19h 55mDelta
lun. 1/264:50 amIST - TYS
2 stops18h 29mDelta
Deal found 11/25$672
This Mytrip deal was found by Cheapflights users on 11/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Mytrip is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
vie. 1/167:15 amTYS - IST
3 stops29h 40mMultiple Airlines
vie. 1/3012:05 pmIST - TYS
3 stops31h 04mMultiple Airlines
Deal found 11/25$1,423
This KLM deal was found by Cheapflights users on 11/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure KLM is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
vie. 1/231:00 pmTYS - SAW
2 stops20h 25mKLM
mar. 1/279:00 amSAW - TYS
2 stops19h 47mKLM
Deal found 11/23$1,539
This Orbitz deal was found by Cheapflights users on 11/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Orbitz is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
vie. 1/166:51 pmTYS - SAW
2 stops57h 19mMultiple Airlines
vie. 1/3011:25 amSAW - TYS
2 stops42h 29mMultiple Airlines
Deal found 11/25$1,716
This United Airlines deal was found by Cheapflights users on 11/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
mié. 1/212:25 pmTYS - IST
2 stops18h 20mUnited Airlines
jue. 2/57:55 amIST - TYS
2 stops19h 32mUnited Airlines
Deal found 11/25$3,871
This oojo deal was found by Cheapflights users on 11/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure oojo is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
jue. 1/155:36 pmTYS - SAW
2 stops34h 34mQatar Airways
jue. 1/291:40 pmSAW - TYS
2 stops39h 16mQatar Airways
Deal found 11/25$9,347

Cheapflights Fare Finder

 
Customize your flight search to find flights from Knoxville to Istanbul that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated noviembre 26, 2025.
Use the filters below to find and compare flights from Knoxville to Istanbul that are best for you.

Fly from

Knoxville

Fly to

Istanbul

Route

Depart

Return

Price

KnoxvilleIstanbul

TYS - IST

TYSIST

Knoxville McGhee Tyson

lun. 1/19

5:29 pm-5:45 pm

2 stops40h 16m

Istanbul

mar. 2/3

6:30 am-8:52 pm

2 stops22h 22m

$562

KnoxvilleIstanbul

TYS - IST

TYSIST

Knoxville McGhee Tyson

vie. 1/16

2:19 pm-5:25 pm

2 stops19h 06m

Istanbul

vie. 1/30

8:10 am-8:56 pm

2 stops20h 46m

$564

KnoxvilleIstanbul

TYS - IST

TYSIST

Knoxville McGhee Tyson

vie. 1/23

7:20 pm-6:05 pm

2 stops14h 45m

Istanbul

mar. 1/27

6:30 am-7:27 pm

2 stops20h 57m

$572

KnoxvilleIstanbul

TYS - IST

TYSIST

Knoxville McGhee Tyson

vie. 1/23

2:25 pm-6:05 pm

2 stops19h 40m

Istanbul

mar. 1/27

6:30 am-8:52 pm

2 stops22h 22m

$572

KnoxvilleIstanbul

TYS - IST

TYSIST

Knoxville McGhee Tyson

lun. 1/19

1:00 pm-3:50 am

2 stops30h 50m

Istanbul

lun. 2/2

4:50 am-11:45 pm

2 stops26h 55m

$599

KnoxvilleIstanbul

TYS - IST

TYSIST

Knoxville McGhee Tyson

vie. 1/16

6:09 pm-3:50 am

2 stops25h 41m

Istanbul

jue. 1/29

4:50 am-8:47 pm

2 stops23h 57m

$661

KnoxvilleIstanbul

TYS - IST

TYSIST

Knoxville McGhee Tyson

vie. 1/23

1:00 pm-4:55 pm

2 stops19h 55m

Istanbul

lun. 1/26

4:50 am-3:19 pm

2 stops18h 29m

$672

KnoxvilleIstanbul

TYS - SAW

TYSSAW

Knoxville McGhee Tyson

lun. 1/19

1:00 pm-5:25 pm

2 stops20h 25m

Istanbul Sabiha Gokcen

mar. 2/3

9:00 am-8:47 pm

2 stops19h 47m

$1,241

KnoxvilleIstanbul

TYS - IST

TYSIST

Knoxville McGhee Tyson

lun. 1/19

7:15 am-6:10 pm

1 stop26h 55m

Istanbul

mar. 2/3

3:20 pm-8:39 am

2 stops49h 19m

$1,268

KnoxvilleIstanbul

TYS - IST

TYSIST

Knoxville McGhee Tyson

vie. 1/16

7:15 am-8:55 pm

3 stops29h 40m

Istanbul

vie. 1/30

12:05 pm-11:09 am

3 stops31h 04m

$1,423

Flights are sorted by cheapest round-trip flights first.

Deals found on 11/26

Showing 1-10 of 16 results
1
2

Best time to book a flight from Knoxville to Istanbul

Have a flexible travel schedule? Discover the best time to fly to Istanbul from Knoxville with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Knoxville to Istanbul

What is the cheapest month to book a flight from Knoxville to Istanbul?

Currently, February is the cheapest month in which you can book a flight from Knoxville to Istanbul (average of $554). Flying from Knoxville to Istanbul in June is currently the most expensive (average of $1,362). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

What is the cheapest time of day to fly from TYS to IST?

Find hourly flight availability from Knoxville to Istanbul. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated noviembre 26, 2025.

Unlike in the morning, when flights are generally more expensive, you can save up to 15% on flights from Knoxville to Istanbul by exploring options for tickets at noon.

How much does it cost to fly round-trip from Knoxville to Istanbul?

Reviews of airlines servicing Istanbul

Get insights into the airlines that provide service to Istanbul. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Istanbul. Reviews last updated noviembre 26, 2025.
Read reviews from past customers who have flown Delta, United Airlines, and American Airlines from Knoxville to Istanbul. Users can see the overall rating for each airline as well as how each is rated in terms of entertainment options, comfort, food, crew/service, and boarding process.
Delta
7.9
Good
7,998 reviews

Overall

7.9

Boarding

8.1

Food

7.3

Entertainment

7.9

Comfort

7.9

Crew

8.5

Reviews

1 / 20
6.0
Good

Jim,Nov 2025

AVL - ATL

The exit row seats without a seat in front are great for leg room but don’t have a fold out entertainment console so you’re forced to use the screen several feet in front of you (there is, at least, a remote). Best to bring a tablet loaded with entertainment or a book.
Delta
7.9
Good
7,998 reviews
Delta
7.9
Good
7,998 reviews

Overall

7.9

Boarding

8.1

Food

7.3

Entertainment

7.9

Comfort

7.9

Crew

8.5

Reviews

1 / 20
6.0
Good

Jim,Nov 2025

AVL - ATL

The exit row seats without a seat in front are great for leg room but don’t have a fold out entertainment console so you’re forced to use the screen several feet in front of you (there is, at least, a remote). Best to bring a tablet loaded with entertainment or a book.
United Airlines
7.4
Good
9,046 reviews
Delta
7.9
Good
7,998 reviews

Overall

7.9

Boarding

8.1

Food

7.3

Entertainment

7.9

Comfort

7.9

Crew

8.5

Reviews

1 / 20
6.0
Good

Jim,Nov 2025

AVL - ATL

The exit row seats without a seat in front are great for leg room but don’t have a fold out entertainment console so you’re forced to use the screen several feet in front of you (there is, at least, a remote). Best to bring a tablet loaded with entertainment or a book.
American Airlines
7.2
Good
11,038 reviews
Delta
7.9
Good
7,998 reviews

Overall

7.9

Boarding

8.1

Food

7.3

Entertainment

7.9

Comfort

7.9

Crew

8.5

Reviews

1 / 20
6.0
Good

Jim,Nov 2025

AVL - ATL

The exit row seats without a seat in front are great for leg room but don’t have a fold out entertainment console so you’re forced to use the screen several feet in front of you (there is, at least, a remote). Best to bring a tablet loaded with entertainment or a book.
British Airways
6.7
Okay
7,539 reviews
Delta
7.9
Good
7,998 reviews

Overall

7.9

Boarding

8.1

Food

7.3

Entertainment

7.9

Comfort

7.9

Crew

8.5

Reviews

1 / 20
6.0
Good

Jim,Nov 2025

AVL - ATL

The exit row seats without a seat in front are great for leg room but don’t have a fold out entertainment console so you’re forced to use the screen several feet in front of you (there is, at least, a remote). Best to bring a tablet loaded with entertainment or a book.

Related info for your journey

Find useful and relevant information for your journey from Knoxville to Istanbul. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • What airport do you fly from for flights from Knoxville to Istanbul?

    If you book a flight to Istanbul from Knoxville, you will be flying from McGhee Tyson, which is the city’s only airport. Knoxville McGhee Tyson (TYS) is located 11.3 mi from the center of Knoxville. There are 0 flights from McGhee Tyson to Istanbul per day from 4 different airlines.

  • How long is the flight from Knoxville to Istanbul?

    Lufthansa, British Airways, and United Airlines can get you from Knoxville to Istanbul in just under 14h 45m. Your travel time can differ by up to 25h 31m. Airlines will cover a distance of 5617 mi. Both multi-stop and nonstop flights can be found to your destination and back.

  • What are the cheapest airlines flying from Knoxville to Istanbul round-trip?

    Our cheapest airline available from Knoxville to Istanbul is British Airways. Our recent data shows that you can find tickets from as low as $758 on this airline. Additional options worth looking into are American Airlines and United Airlines, starting at $770 and $930 round-trip. These flights start at 28% lower than the current average price 3 months from now.

  • Can I find deals for flights from Knoxville to Istanbul that include hotel bookings?

    Yes. In addition to deals on Knoxville to Istanbul flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Knoxville to Istanbul?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Knoxville to Istanbul.

  • Can I find deals for business class flights from Knoxville to Istanbul?

    Yes. Cheapflights offers flight deals from Knoxville to Istanbul by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Knoxville to Istanbul?

    Currently, February is the cheapest month in which you can book a flight from Knoxville to Istanbul (average of $554). Flying from Knoxville to Istanbul in June is currently the most expensive (average of $1,362). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

Browse thousands of different options on Cheapflights for your next trip

Toggle through the tabs below to find thousands of options on Cheapflights for your next trip.

Top 4 airlines flying from Knoxville to Istanbul

Discover the top 4 airlines that operate flights from Knoxville to Istanbul. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated noviembre 26, 2025.
AirlineCheapestAverageFlexibilityOn-time
British AirwaysCheapest$758Average$1,071FlexibilityNo cancel feeOn-time70%
American AirlinesCheapest$770Average$1,173FlexibilityNo cancel feeOn-time71%
United AirlinesCheapest$930Average$1,180FlexibilityNo cancel feeOn-time69%
DeltaCheapest$954Average$1,185FlexibilityNo cancel feeOn-timeN/A

100% Free

Cheapflights is completely free to use, so you can start saving the moment you arrive.

Book with Flexibility

Our users can plan ahead with confidence and find flights with no change fees

Travel Smart

Millions of people come to us for their flight needs every year. We help make travel planning easy by providing useful insights and data-driven graphs that can inform your decisions.