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$369+ Cheap flights from Knoxville (TYS) to Istanbul

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 3/29. Fares are subject to change and may not be available on all flights or dates of travel.
TYS — IST
Feb 19 — Feb 261
Thu 2/19
Thu 2/26
1 adult, Economy
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Cheap flight deals from Knoxville to Istanbul

Cheapest flights from Knoxville to Istanbul
Explore the most affordable flight options available from Knoxville to Istanbul. Find the lowest fares from popular airlines and budget airlines, with prices last updated on January 20, 2026.

This United Airlines deal was found by Cheapflights users on 1/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 2/251:50 pm
TYS
-
IST
2 stops20h 15m
United Airlines
Sun 3/16:30 am
IST
-
TYS
2 stops25h 14m
United Airlines
Deal found 1/19$561
This Gotogate deal was found by Cheapflights users on 1/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Gotogate is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 3/56:10 am
TYS
-
IST
2 stops35h 00m
British Airways
Thu 3/127:35 am
IST
-
TYS
2 stops20h 30m
British Airways
Deal found 1/18$625
This United Airlines deal was found by Cheapflights users on 1/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 3/510:55 am
TYS
-
IST
2 stops27h 50m
United Airlines
Thu 3/126:30 am
IST
-
TYS
2 stops41h 15m
United Airlines
Deal found 1/19$641
This FlightHub deal was found by Cheapflights users on 1/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure FlightHub is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 8/106:21 am
TYS
-
IST
2 stops29h 34m
British Airways
Mon 8/173:35 pm
IST
-
TYS
2 stops35h 46m
British Airways
Deal found 1/18$668
This Kiwi.com deal was found by Cheapflights users on 1/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 3/56:30 am
TYS
-
IST
1 stop22h 55m
Multiple Airlines
Thu 3/128:20 am
IST
-
TYS
2 stops41h 07m
Multiple Airlines
Deal found 1/18$1,134
This Iberia deal was found by Cheapflights users on 1/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Iberia is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 2/264:02 pm
TYS
-
SAW
2 stops21h 03m
Iberia
Sun 3/111:25 am
SAW
-
TYS
2 stops41h 15m
Iberia
Deal found 1/19$1,169
This Kiwi.com deal was found by Cheapflights users on 1/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 8/101:07 pm
TYS
-
IST
1 stop18h 43m
Multiple Airlines
Mon 8/175:50 am
IST
-
TYS
2 stops18h 14m
Multiple Airlines
Deal found 1/18$1,367
This Air Canada deal was found by Cheapflights users on 1/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Air Canada is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 3/59:40 am
TYS
-
IST
3 stops24h 25m
Air Canada
Thu 3/126:30 am
IST
-
TYS
3 stops35h 19m
Air Canada
Deal found 1/18$1,589
This Travelocity deal was found by Cheapflights users on 1/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Travelocity is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 8/105:37 pm
TYS
-
SAW
2 stops42h 58m
Iberia
Mon 8/1710:00 am
SAW
-
TYS
2 stops42h 23m
Iberia
Deal found 1/18$1,955
This KAYAK deal was found by Cheapflights users on 1/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure KAYAK is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 8/105:50 am
TYS
-
IST
2 stops32h 20m
Ethiopian Air
Mon 8/1711:55 pm
IST
-
TYS
3 stops45h 47m
Ethiopian Air
Deal found 1/18$3,150
This Justfly.com deal was found by Cheapflights users on 1/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Justfly.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/309:47 am
TYS
-
SAW
2 stops43h 23m
Qatar Airways
Mon 11/91:40 pm
SAW
-
TYS
2 stops39h 24m
Qatar Airways
Deal found 1/18$8,297
This Emirates deal was found by Cheapflights users on 1/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Emirates is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 3/51:53 pm
TYS
-
SAW
2 stops39h 27m
Emirates
Thu 3/122:20 pm
SAW
-
TYS
2 stops40h 24m
Emirates
Deal found 1/19$11,210

Find flight deals from Knoxville to Istanbul

Discover tips and strategies to find the most affordable flight options for your journey from Knoxville (TYS) to Istanbul (TR5). Learn about various techniques such as flexible date searches, comparing prices across and setting up price alerts. Use these methods to find the cheapest flights available for your travel needs. Data last updated January 20, 2026.

Round-trip from

$561
(United Airlines)

One-way from

$369
(Kiwi.com)

Popular in

June

Cheapest in

February

Average price

$1,040
From Knoxville McGhee Tyson to Istanbul
Search Deals
One-way flight from Knoxville McGhee Tyson to Istanbul
Search Deals
Highest demand for flights based on searches. 23% potential increase in price ($312 potential increase over avg. RT price).
Search Deals
Cheapest flight prices on average. 3% potential price decrease ($41 potential savings vs. average RT price).
Search Deals
Average for round-trip flights in January 2026
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Cheapflights Fare Finder

 
Customize your flight search to find flights from Knoxville to Istanbul that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated January 20, 2026.
Use the filters below to find and compare flights from Knoxville to Istanbul that are best for you.

Fly from

Knoxville

Fly to

Istanbul

Route

Depart

Return

Price

KnoxvilleIstanbul

TYS - IST

TYSIST

Knoxville McGhee Tyson

Wed 2/25

2:21 pm-6:05 pm

2 stops19h 44m

Istanbul

Sun 3/1

6:30 am-7:55 pm

2 stops21h 25m

$561

KnoxvilleIstanbul

TYS - IST

TYSIST

Knoxville McGhee Tyson

Thu 3/5

6:10 am-1:10 am

2 stops35h 00m

Istanbul

Thu 3/12

7:35 am-9:05 pm

2 stops20h 30m

$625

KnoxvilleIstanbul

TYS - IST

TYSIST

Knoxville McGhee Tyson

Thu 3/5

10:55 am-10:45 pm

2 stops27h 50m

Istanbul

Thu 3/12

6:30 am-4:45 pm

2 stops41h 15m

$641

KnoxvilleIstanbul

TYS - IST

TYSIST

Knoxville McGhee Tyson

Thu 3/5

6:30 am-1:25 pm

1 stop22h 55m

Istanbul

Thu 3/12

8:20 am-6:27 pm

2 stops41h 07m

$1,134

KnoxvilleIstanbul

TYS - SAW

TYSSAW

Knoxville McGhee Tyson

Thu 2/26

4:02 pm-9:05 pm

2 stops21h 03m

Istanbul Sabiha Gokcen

Sun 3/1

11:25 am-8:40 pm

2 stops41h 15m

$1,169

KnoxvilleIstanbul

TYS - IST

TYSIST

Knoxville McGhee Tyson

Thu 3/5

9:40 am-6:05 pm

3 stops24h 25m

Istanbul

Thu 3/12

6:30 am-10:49 am

3 stops35h 19m

$1,589

KnoxvilleIstanbul

TYS - SAW

TYSSAW

Knoxville McGhee Tyson

Thu 3/5

1:53 pm-1:20 pm

2 stops39h 27m

Istanbul Sabiha Gokcen

Thu 3/12

2:20 pm-11:44 pm

2 stops40h 24m

$11,210

KnoxvilleIstanbul

TYS - SAW

TYSSAW

Knoxville McGhee Tyson

Sun 3/29

6:39 pm-12:20 pm

3 stops58h 41m

$369

KnoxvilleIstanbul

TYS - SAW

TYSSAW

Knoxville McGhee Tyson

Wed 4/1

8:30 am-1:55 pm

3 stops46h 25m

$397

KnoxvilleIstanbul

TYS - IST

TYSIST

Knoxville McGhee Tyson

Sun 3/29

6:39 pm-11:25 pm

3 stops45h 46m

$410

Flights are sorted by cheapest round-trip flights first.

Deals found on 1/18

Showing 1-10 of 19 results
1
2

Best time to book a flight from Knoxville to Istanbul

Have a flexible travel schedule? Discover the best time to fly to Istanbul from Knoxville with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Knoxville to Istanbul

What is the cheapest month to book a flight from Knoxville to Istanbul?

Currently, February is the cheapest month in which you can book a flight from Knoxville to Istanbul (average of $554). Flying from Knoxville to Istanbul in June is currently the most expensive (average of $1,362). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

Reviews of airlines servicing Istanbul

Get insights into the airlines that provide service to Istanbul. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Istanbul. Reviews last updated January 20, 2026.
Read reviews from past customers who have flown Delta, United Airlines, and American Airlines from Knoxville to Istanbul. Users can see the overall rating for each airline as well as how each is rated in terms of entertainment options, comfort, food, crew/service, and boarding process.
Delta
7.9
Good
8,085 reviews

Boarding

8.1

Crew

8.5

Food

7.2

Overall

7.9

Comfort

7.9

Entertainment

7.8

Reviews

1 / 20
6.0
Good

Jim,Nov 2025

AVL - ATL

The exit row seats without a seat in front are great for leg room but don’t have a fold out entertainment console so you’re forced to use the screen several feet in front of you (there is, at least, a remote). Best to bring a tablet loaded with entertainment or a book.
Delta
7.9
Good
8,085 reviews
Delta
7.9
Good
8,085 reviews

Boarding

8.1

Crew

8.5

Food

7.2

Overall

7.9

Comfort

7.9

Entertainment

7.8

Reviews

1 / 20
6.0
Good

Jim,Nov 2025

AVL - ATL

The exit row seats without a seat in front are great for leg room but don’t have a fold out entertainment console so you’re forced to use the screen several feet in front of you (there is, at least, a remote). Best to bring a tablet loaded with entertainment or a book.
United Airlines
7.4
Good
9,189 reviews
Delta
7.9
Good
8,085 reviews

Boarding

8.1

Crew

8.5

Food

7.2

Overall

7.9

Comfort

7.9

Entertainment

7.8

Reviews

1 / 20
6.0
Good

Jim,Nov 2025

AVL - ATL

The exit row seats without a seat in front are great for leg room but don’t have a fold out entertainment console so you’re forced to use the screen several feet in front of you (there is, at least, a remote). Best to bring a tablet loaded with entertainment or a book.
American Airlines
7.2
Good
11,169 reviews
Delta
7.9
Good
8,085 reviews

Boarding

8.1

Crew

8.5

Food

7.2

Overall

7.9

Comfort

7.9

Entertainment

7.8

Reviews

1 / 20
6.0
Good

Jim,Nov 2025

AVL - ATL

The exit row seats without a seat in front are great for leg room but don’t have a fold out entertainment console so you’re forced to use the screen several feet in front of you (there is, at least, a remote). Best to bring a tablet loaded with entertainment or a book.
British Airways
6.7
Okay
7,690 reviews
Delta
7.9
Good
8,085 reviews

Boarding

8.1

Crew

8.5

Food

7.2

Overall

7.9

Comfort

7.9

Entertainment

7.8

Reviews

1 / 20
6.0
Good

Jim,Nov 2025

AVL - ATL

The exit row seats without a seat in front are great for leg room but don’t have a fold out entertainment console so you’re forced to use the screen several feet in front of you (there is, at least, a remote). Best to bring a tablet loaded with entertainment or a book.

Related info for your journey

Find useful and relevant information for your journey from Knoxville to Istanbul. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • What airport do you fly from for flights from Knoxville to Istanbul?

    If you book a flight to Istanbul from Knoxville, you will be flying from McGhee Tyson, which is the city’s only airport. Knoxville McGhee Tyson (TYS) is located 11.3 mi from the center of Knoxville. There are 0 flights from McGhee Tyson to Istanbul per day from 4 different airlines.

  • How long is the flight from Knoxville to Istanbul?

    United Airlines, British Airways, and Iberia can get you from Knoxville to Istanbul in just under 19h 44m. Your travel time can differ by up to 15h 16m. Airlines will cover a distance of 5617 mi. Both multi-stop and nonstop flights can be found to your destination and back.

  • What are the cheapest airlines flying from Knoxville to Istanbul round-trip?

    Our cheapest airline available from Knoxville to Istanbul is British Airways. Our recent data shows that you can find tickets from as low as $758 on this airline. Additional options worth looking into are American Airlines and United Airlines, starting at $770 and $930 round-trip. These flights start at 27% lower than the current average price 3 months from now.

  • Can I find deals for flights from Knoxville to Istanbul that include hotel bookings?

    Yes. In addition to deals on Knoxville to Istanbul flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Knoxville to Istanbul?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Knoxville to Istanbul.

  • Can I find deals for business class flights from Knoxville to Istanbul?

    Yes. Cheapflights offers flight deals from Knoxville to Istanbul by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Knoxville to Istanbul?

    Currently, February is the cheapest month in which you can book a flight from Knoxville to Istanbul (average of $554). Flying from Knoxville to Istanbul in June is currently the most expensive (average of $1,362). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

Browse thousands of different options on Cheapflights for your next trip

Toggle through the tabs below to find thousands of options on Cheapflights for your next trip.

Top 4 airlines flying from Knoxville to Istanbul

Discover the top 4 airlines that operate flights from Knoxville to Istanbul. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated January 20, 2026.
AirlineCheapestAverageFlexibilityOn-time
British AirwaysCheapest$758Average$1,071FlexibilityNo cancel feeOn-time70%
American AirlinesCheapest$770Average$1,170FlexibilityNo cancel feeOn-time71%
United AirlinesCheapest$930Average$1,208FlexibilityNo cancel feeOn-time69%
DeltaCheapest$1,061Average$1,316FlexibilityNo cancel feeOn-timeN/A

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