HomeSearch by dateVacation packagesHotelsFlight dealsCar rentalTravel tips & news
Istanbul

$638+ Cheap flights from Knoxville (TYS) to Istanbul

This is the cheapest round-trip flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 11/12. Fares are subject to change and may not be available on all flights or dates of travel.
TYS — IST
Jul 5 — Jul 121
Sat 7/5
Sat 7/12
1 adult, Economy
We work with more than 300 partners to bring you better travel deals

Find cheap flights from Knoxville to Istanbul with Cheapflights

1. Tell us where you want to go

Enter your travel information like dates, passengers, trip type (one-way or round trip), and preferred cabin class then click “Find deals”

2. Select your favorite providers

We find the providers serving your travel needs. Choose up to four travel providers to compare side-by-side for flights, hotels, or car rentals.

3. Compare prices and book

Review each provider’s pricing and select the best option for you! Book through your favorite provider’s website for a seamless experience.

Cheap flight deals from Knoxville to Istanbul

Discover tips and strategies to find the most affordable flight options for your journey from Knoxville (TYS) to Istanbul (TR5). Learn about various techniques such as flexible date searches, comparing prices across and setting up price alerts. Use these methods to find the cheapest flights available for your travel needs. Data last updated June 30, 2025.

Round-trip from

$638
(FlightHub)

Popular in

October

Cheapest in

November

Average price

$1,517
From Knoxville McGhee Tyson to Istanbul
Search Deals
Highest demand for flights based on searches. 9% potential increase in price ($128 potential increase over avg. RT price).
Search Deals
Cheapest flight prices on average. 9% potential price decrease ($111 potential savings vs. average RT price).
Search Deals
Average for round-trip flights in June 2025
Search Deals

Find flight deals from Knoxville to Istanbul

Cheapest flights from Knoxville to Istanbul
Explore the most affordable flight options available from Knoxville to Istanbul. Find the lowest fares from popular airlines and budget airlines, with prices last updated on June 30, 2025.

This FlightHub deal was found by Cheapflights users on 6/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure FlightHub is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 11/122:25 pmTYS - IST
2 stops24h 20mLufthansa
Fri 11/216:30 amIST - TYS
2 stops25h 29mLufthansa
Deal found 6/28$638
This Lufthansa deal was found by Cheapflights users on 6/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Lufthansa is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 12/77:26 pmTYS - IST
2 stops19h 19mMultiple Airlines
Fri 12/196:30 amIST - TYS
2 stops25h 12mMultiple Airlines
Deal found 6/28$639
This Air Canada deal was found by Cheapflights users on 6/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Air Canada is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 11/89:50 amTYS - IST
3 stops24h 35mAir Canada
Sat 11/228:50 amIST - TYS
3 stops23h 09mAir Canada
Deal found 6/28$747
This Delta deal was found by Cheapflights users on 6/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 8/32:36 pmTYS - IST
2 stops29h 49mDelta
Fri 8/154:20 amIST - TYS
2 stops23h 57mDelta
Deal found 6/29$865
This United Airlines deal was found by Cheapflights users on 6/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 8/39:55 amTYS - IST
2 stops20h 10mUnited Airlines
Fri 8/156:10 amIST - TYS
3 stops23h 27mUnited Airlines
Deal found 6/29$1,204
This British Airways deal was found by Cheapflights users on 6/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure British Airways is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 7/21:56 pmTYS - IST
2 stops22h 04mBritish Airways
Mon 7/78:15 pmIST - TYS
2 stops31h 24mBritish Airways
Deal found 6/28$1,553
This Travelocity deal was found by Cheapflights users on 6/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Travelocity is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 7/21:56 pmTYS - SAW
2 stops18h 09mBritish Airways
Mon 7/73:00 pmSAW - TYS
2 stops36h 39mBritish Airways
Deal found 6/28$1,572
This oojo deal was found by Cheapflights users on 6/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure oojo is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 11/84:33 pmTYS - SAW
2 stops35h 37mQatar Airways
Sat 11/228:10 pmSAW - TYS
2 stops27h 11mQatar Airways
Deal found 6/28$1,741
This KLM deal was found by Cheapflights users on 6/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure KLM is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 8/35:57 pmTYS - SAW
2 stops16h 08mKLM
Fri 8/158:45 amSAW - TYS
2 stops19h 32mKLM
Deal found 6/29$2,252
This oojo deal was found by Cheapflights users on 6/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure oojo is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 11/125:45 amTYS - IST
2 stops31h 25mEthiopian Air
Thu 11/2012:10 amIST - TYS
3 stops46h 38mEthiopian Air
Deal found 6/28$2,958
This oojo deal was found by Cheapflights users on 6/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure oojo is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 9/17:55 amTYS - IST
2 stops29h 35mRoyal Jordanian
Fri 10/312:05 pmIST - TYS
2 stops38h 29mRoyal Jordanian
Deal found 6/28$4,096

Cheapflights Fare Finder

Customize your flight search to find flights from Knoxville to Istanbul that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated June 30, 2025.
Use the filters below to find and compare flights from Knoxville to Istanbul that are best for you.

Fly from

Knoxville

Fly to

Istanbul

Route

Depart

Return

Price

KnoxvilleIstanbul

TYS - IST

TYSIST

Knoxville McGhee Tyson

Wed 11/12

2:25 pm-10:45 pm

2 stops24h 20m

Istanbul

Fri 11/21

6:30 am-11:59 pm

2 stops25h 29m

$638

KnoxvilleIstanbul

TYS - IST

TYSIST

Knoxville McGhee Tyson

Sun 12/7

7:26 pm-10:45 pm

2 stops19h 19m

Istanbul

Fri 12/19

6:30 am-11:42 pm

2 stops25h 12m

$639

KnoxvilleIstanbul

TYS - IST

TYSIST

Knoxville McGhee Tyson

Sat 11/8

9:50 am-6:25 pm

3 stops24h 35m

Istanbul

Sat 11/22

8:50 am-11:59 pm

3 stops23h 09m

$747

KnoxvilleIstanbul

TYS - IST

TYSIST

Knoxville McGhee Tyson

Sun 8/3

2:36 pm-3:25 am

2 stops29h 49m

Istanbul

Fri 8/15

4:20 am-9:17 pm

2 stops23h 57m

$865

KnoxvilleIstanbul

TYS - IST

TYSIST

Knoxville McGhee Tyson

Sun 8/3

9:55 am-1:05 pm

2 stops20h 10m

Istanbul

Fri 8/15

6:10 am-10:37 pm

3 stops23h 27m

$1,204

KnoxvilleIstanbul

TYS - SAW

TYSSAW

Knoxville McGhee Tyson

Sat 11/8

4:33 pm-12:10 pm

2 stops35h 37m

Istanbul Sabiha Gokcen

Sat 11/22

8:10 pm-3:21 pm

2 stops27h 11m

$1,741

KnoxvilleIstanbul

TYS - SAW

TYSSAW

Knoxville McGhee Tyson

Sun 8/3

5:57 pm-5:05 pm

2 stops16h 08m

Istanbul Sabiha Gokcen

Fri 8/15

8:45 am-9:17 pm

2 stops19h 32m

$2,252

KnoxvilleIstanbul

TYS - IST

TYSIST

Knoxville McGhee Tyson

Wed 11/12

5:45 am-9:10 pm

2 stops31h 25m

Istanbul

Thu 11/20

12:10 am-2:48 pm

3 stops46h 38m

$2,958

KnoxvilleIstanbul

TYS - IST

TYSIST

Knoxville McGhee Tyson

Mon 9/1

7:55 am-8:30 pm

2 stops29h 35m

Istanbul

Fri 10/31

2:05 pm-9:34 pm

2 stops38h 29m

$4,096

KnoxvilleIstanbul

TYS - SAW

TYSSAW

Knoxville McGhee Tyson

Mon 9/1

6:12 pm-3:20 pm

2 stops38h 08m

Istanbul Sabiha Gokcen

Fri 10/31

7:30 pm-9:34 pm

2 stops33h 04m

$4,769

Flights are sorted by cheapest round-trip flights first.

Deals found on 6/28

Best time to book a flight from Knoxville to Istanbul

Have a flexible travel schedule? Discover the best time to fly to Istanbul from Knoxville with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Knoxville to Istanbul

What is the cheapest time of day to fly from TYS to IST?

Find hourly flight availability from Knoxville to Istanbul. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated June 30, 2025.

Unlike in the morning, when flights are generally more expensive, you can save up to 16% on flights from Knoxville to Istanbul by exploring options for tickets at noon.

Reviews of airlines servicing Istanbul

Get insights into the airlines that provide service to Istanbul. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Istanbul. Reviews last updated June 30, 2025.
Read reviews from past customers who have flown Delta, KLM, and Qatar Airways from Knoxville to Istanbul. Users can see the overall rating for each airline as well as how each is rated in terms of entertainment options, comfort, food, crew/service, and boarding process.
Delta
8.0
Very good
7,973 reviews

Entertainment

7.9

Overall

8.0

Crew

8.5

Comfort

7.9

Boarding

8.2

Food

7.3

Reviews

1 / 20
10.0
Excellent

Kim,May 2025

PIH - SLC

This trip was fine even with delay I had plenty of time to get connection flight!
Delta
8.0
Very good
7,973 reviews
Delta
8.0
Very good
7,973 reviews

Entertainment

7.9

Overall

8.0

Crew

8.5

Comfort

7.9

Boarding

8.2

Food

7.3

Reviews

1 / 20
10.0
Excellent

Kim,May 2025

PIH - SLC

This trip was fine even with delay I had plenty of time to get connection flight!
KLM
7.8
Good
1,365 reviews
Delta
8.0
Very good
7,973 reviews

Entertainment

7.9

Overall

8.0

Crew

8.5

Comfort

7.9

Boarding

8.2

Food

7.3

Reviews

1 / 20
10.0
Excellent

Kim,May 2025

PIH - SLC

This trip was fine even with delay I had plenty of time to get connection flight!
Qatar Airways
7.4
Good
3,596 reviews
Delta
8.0
Very good
7,973 reviews

Entertainment

7.9

Overall

8.0

Crew

8.5

Comfort

7.9

Boarding

8.2

Food

7.3

Reviews

1 / 20
10.0
Excellent

Kim,May 2025

PIH - SLC

This trip was fine even with delay I had plenty of time to get connection flight!
United Airlines
7.4
Good
8,852 reviews
Delta
8.0
Very good
7,973 reviews

Entertainment

7.9

Overall

8.0

Crew

8.5

Comfort

7.9

Boarding

8.2

Food

7.3

Reviews

1 / 20
10.0
Excellent

Kim,May 2025

PIH - SLC

This trip was fine even with delay I had plenty of time to get connection flight!
Ethiopian Air
7.3
Good
788 reviews
Delta
8.0
Very good
7,973 reviews

Entertainment

7.9

Overall

8.0

Crew

8.5

Comfort

7.9

Boarding

8.2

Food

7.3

Reviews

1 / 20
10.0
Excellent

Kim,May 2025

PIH - SLC

This trip was fine even with delay I had plenty of time to get connection flight!

Related info for your journey

Find useful and relevant information for your journey from Knoxville to Istanbul. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • What airport do you fly from for flights from Knoxville to Istanbul?

    If you book a flight to Istanbul from Knoxville, you will be flying from McGhee Tyson, which is the city’s only airport. Knoxville McGhee Tyson (TYS) is located 11.3 mi from the center of Knoxville. There are 0 flights from McGhee Tyson to Istanbul per day from 6 different airlines.

  • What are the cheapest airlines flying from Knoxville to Istanbul round-trip?

    Our cheapest airline available from Knoxville to Istanbul is Lufthansa. Our recent data shows that you can find tickets from as low as $638 on this airline. Additional options worth looking into are Air Canada and Delta, starting at $747 and $865 round-trip. These flights start at 50% lower than the current average price 3 months from now.

  • Can I find deals for flights from Knoxville to Istanbul that include hotel bookings?

    Yes. In addition to deals on Knoxville to Istanbul flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Knoxville to Istanbul?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Knoxville to Istanbul.

  • Can I find deals for business class flights from Knoxville to Istanbul?

    Yes. Cheapflights offers flight deals from Knoxville to Istanbul by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Knoxville to Istanbul?

    Currently, November is the cheapest month in which you can book a flight from Knoxville to Istanbul (average of $923). Flying from Knoxville to Istanbul in June is currently the most expensive (average of $1,362). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

Browse thousands of different options on Cheapflights for your next trip

Toggle through the tabs below to find thousands of options on Cheapflights for your next trip.

Top 6 airlines flying from Knoxville to Istanbul

Discover the top 6 airlines that operate flights from Knoxville to Istanbul. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated June 30, 2025.
AirlineCheapestAverageFlexibilityOn-time
American AirlinesCheapest$770Average$1,170FlexibilityNo cancel feeOn-time71%
LufthansaCheapest$781Average$1,109FlexibilityNo cancel feeOn-time76%
DeltaCheapest$797Average$1,168FlexibilityNo cancel feeOn-timeN/A
British AirwaysCheapest$933Average$1,376FlexibilityNo cancel feeOn-time70%
United AirlinesCheapest$987Average$1,180FlexibilityNo cancel feeOn-time69%
Air FranceCheapest$2,396Average$2,396FlexibilityNo cancel feeOn-time77%

100% Free

Cheapflights is completely free to use, so you can start saving the moment you arrive.

Book with Flexibility

Our users can plan ahead with confidence and find flights with no change fees

Travel Smart

Millions of people come to us for their flight needs every year. We help make travel planning easy by providing useful insights and data-driven graphs that can inform your decisions.