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$560+ Cheap flights from Knoxville (TYS) to Istanbul

This is the cheapest round-trip flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 2/13. Fares are subject to change and may not be available on all flights or dates of travel.
TYS — IST
Jan 29 — Feb 51
Thu 1/29
Thu 2/5
1 adult, Economy
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Cheap flight deals from Knoxville to Istanbul

Cheapest flights from Knoxville to Istanbul
Explore the most affordable flight options available from Knoxville to Istanbul. Find the lowest fares from popular airlines and budget airlines, with prices last updated on December 30, 2025.

This AranGrant deal was found by Cheapflights users on 12/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure AranGrant is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 12/305:35 pmTYS - IST
2 stops45h 10mLufthansa
Mon 1/56:30 amIST - TYS
2 stops21h 21mLufthansa
Deal found 12/29$22,146

Find flight deals from Knoxville to Istanbul

Discover tips and strategies to find the most affordable flight options for your journey from Knoxville (TYS) to Istanbul (TR5). Learn about various techniques such as flexible date searches, comparing prices across and setting up price alerts. Use these methods to find the cheapest flights available for your travel needs. Data last updated December 30, 2025.

Round-trip from

$560
(oojo)

Popular in

June

Cheapest in

February

Average price

$799
From Knoxville McGhee Tyson to Istanbul
Search Deals
Highest demand for flights based on searches. 23% potential increase in price ($321 potential increase over avg. RT price).
Search Deals
Cheapest flight prices on average. 4% potential price decrease ($41 potential savings vs. average RT price).
Search Deals
Average for round-trip flights in December 2025
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Cheapflights Fare Finder

 
Customize your flight search to find flights from Knoxville to Istanbul that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated December 30, 2025.
Use the filters below to find and compare flights from Knoxville to Istanbul that are best for you.

Fly from

Knoxville

Fly to

Istanbul

Route

Depart

Return

Price

KnoxvilleIstanbul

TYS - IST

TYSIST

Knoxville McGhee Tyson

Fri 2/13

11:42 am-5:25 pm

2 stops21h 43m

Istanbul

Fri 2/20

8:10 am-9:07 pm

2 stops20h 57m

$560

KnoxvilleIstanbul

TYS - IST

TYSIST

Knoxville McGhee Tyson

Wed 2/18

11:28 am-5:25 pm

2 stops21h 57m

Istanbul

Wed 2/25

7:35 am-9:28 pm

2 stops21h 53m

$561

KnoxvilleIstanbul

TYS - IST

TYSIST

Knoxville McGhee Tyson

Thu 2/26

4:02 pm-5:30 pm

2 stops17h 28m

Istanbul

Thu 3/19

7:35 am-9:32 pm

2 stops20h 57m

$576

KnoxvilleIstanbul

TYS - IST

TYSIST

Knoxville McGhee Tyson

Thu 2/19

2:21 pm-6:05 pm

2 stops19h 44m

Istanbul

Mon 2/23

6:30 am-11:44 pm

2 stops25h 14m

$577

KnoxvilleIstanbul

TYS - IST

TYSIST

Knoxville McGhee Tyson

Wed 2/18

9:40 am-6:05 pm

3 stops24h 25m

Istanbul

Wed 2/25

6:30 am-7:29 pm

3 stops20h 59m

$587

KnoxvilleIstanbul

TYS - IST

TYSIST

Knoxville McGhee Tyson

Mon 3/2

2:21 pm-10:45 pm

2 stops24h 24m

Istanbul

Mon 3/30

5:55 pm-10:29 pm

2 stops35h 34m

$607

KnoxvilleIstanbul

TYS - IST

TYSIST

Knoxville McGhee Tyson

Thu 2/12

7:25 pm-6:05 pm

2 stops38h 40m

Istanbul

Thu 2/19

6:30 am-11:44 pm

2 stops25h 14m

$682

KnoxvilleIstanbul

TYS - IST

TYSIST

Knoxville McGhee Tyson

Wed 2/11

9:30 am-6:05 pm

3 stops24h 35m

Istanbul

Wed 2/18

6:30 am-7:29 pm

3 stops20h 59m

$690

KnoxvilleIstanbul

TYS - IST

TYSIST

Knoxville McGhee Tyson

Sun 1/25

9:30 am-6:05 pm

3 stops24h 35m

Istanbul

Sun 2/1

6:30 am-10:57 am

3 stops36h 27m

$848

KnoxvilleIstanbul

TYS - SAW

TYSSAW

Knoxville McGhee Tyson

Sun 1/25

1:00 pm-5:25 pm

2 stops20h 25m

Istanbul Sabiha Gokcen

Sun 2/1

9:00 am-11:45 pm

2 stops22h 45m

$879

Flights are sorted by cheapest round-trip flights first.

Deals found on 12/30

Showing 1-10 of 18 results
1
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Best time to book a flight from Knoxville to Istanbul

Have a flexible travel schedule? Discover the best time to fly to Istanbul from Knoxville with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Knoxville to Istanbul

What is the cheapest month to book a flight from Knoxville to Istanbul?

Currently, February is the cheapest month in which you can book a flight from Knoxville to Istanbul (average of $554). Flying from Knoxville to Istanbul in June is currently the most expensive (average of $1,362). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

Reviews of airlines servicing Istanbul

Get insights into the airlines that provide service to Istanbul. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Istanbul. Reviews last updated December 30, 2025.
Read reviews from past customers who have flown Delta, United Airlines, and American Airlines from Knoxville to Istanbul. Users can see the overall rating for each airline as well as how each is rated in terms of entertainment options, comfort, food, crew/service, and boarding process.
Delta
7.9
Good
8,016 reviews

Entertainment

7.8

Crew

8.5

Overall

7.9

Boarding

8.1

Food

7.2

Comfort

7.9

Reviews

1 / 20
6.0
Good

Jim,Nov 2025

AVL - ATL

The exit row seats without a seat in front are great for leg room but don’t have a fold out entertainment console so you’re forced to use the screen several feet in front of you (there is, at least, a remote). Best to bring a tablet loaded with entertainment or a book.
Delta
7.9
Good
8,016 reviews
Delta
7.9
Good
8,016 reviews

Entertainment

7.8

Crew

8.5

Overall

7.9

Boarding

8.1

Food

7.2

Comfort

7.9

Reviews

1 / 20
6.0
Good

Jim,Nov 2025

AVL - ATL

The exit row seats without a seat in front are great for leg room but don’t have a fold out entertainment console so you’re forced to use the screen several feet in front of you (there is, at least, a remote). Best to bring a tablet loaded with entertainment or a book.
United Airlines
7.4
Good
9,124 reviews
Delta
7.9
Good
8,016 reviews

Entertainment

7.8

Crew

8.5

Overall

7.9

Boarding

8.1

Food

7.2

Comfort

7.9

Reviews

1 / 20
6.0
Good

Jim,Nov 2025

AVL - ATL

The exit row seats without a seat in front are great for leg room but don’t have a fold out entertainment console so you’re forced to use the screen several feet in front of you (there is, at least, a remote). Best to bring a tablet loaded with entertainment or a book.
American Airlines
7.2
Good
11,074 reviews
Delta
7.9
Good
8,016 reviews

Entertainment

7.8

Crew

8.5

Overall

7.9

Boarding

8.1

Food

7.2

Comfort

7.9

Reviews

1 / 20
6.0
Good

Jim,Nov 2025

AVL - ATL

The exit row seats without a seat in front are great for leg room but don’t have a fold out entertainment console so you’re forced to use the screen several feet in front of you (there is, at least, a remote). Best to bring a tablet loaded with entertainment or a book.
British Airways
6.7
Okay
7,626 reviews
Delta
7.9
Good
8,016 reviews

Entertainment

7.8

Crew

8.5

Overall

7.9

Boarding

8.1

Food

7.2

Comfort

7.9

Reviews

1 / 20
6.0
Good

Jim,Nov 2025

AVL - ATL

The exit row seats without a seat in front are great for leg room but don’t have a fold out entertainment console so you’re forced to use the screen several feet in front of you (there is, at least, a remote). Best to bring a tablet loaded with entertainment or a book.

Related info for your journey

Find useful and relevant information for your journey from Knoxville to Istanbul. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • What airport do you fly from for flights from Knoxville to Istanbul?

    If you book a flight to Istanbul from Knoxville, you will be flying from McGhee Tyson, which is the city’s only airport. Knoxville McGhee Tyson (TYS) is located 11.3 mi from the center of Knoxville. There are 0 flights from McGhee Tyson to Istanbul per day from 4 different airlines.

  • How long is the flight from Knoxville to Istanbul?

    British Airways, United Airlines, and KLM can get you from Knoxville to Istanbul in just under 19h 44m. Your travel time can differ by up to 1h 59m. Airlines will cover a distance of 5617 mi. Both multi-stop and nonstop flights can be found to your destination and back.

  • What are the cheapest airlines flying from Knoxville to Istanbul round-trip?

    Our cheapest airline available from Knoxville to Istanbul is British Airways. Our recent data shows that you can find tickets from as low as $758 on this airline. Additional options worth looking into are American Airlines and United Airlines, starting at $770 and $930 round-trip. These flights start at 27% lower than the current average price 3 months from now.

  • Can I find deals for flights from Knoxville to Istanbul that include hotel bookings?

    Yes. In addition to deals on Knoxville to Istanbul flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Knoxville to Istanbul?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Knoxville to Istanbul.

  • Can I find deals for business class flights from Knoxville to Istanbul?

    Yes. Cheapflights offers flight deals from Knoxville to Istanbul by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Knoxville to Istanbul?

    Currently, February is the cheapest month in which you can book a flight from Knoxville to Istanbul (average of $554). Flying from Knoxville to Istanbul in June is currently the most expensive (average of $1,362). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

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Top 4 airlines flying from Knoxville to Istanbul

Discover the top 4 airlines that operate flights from Knoxville to Istanbul. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated December 30, 2025.
AirlineCheapestAverageFlexibilityOn-time
British AirwaysCheapest$758Average$1,071FlexibilityNo cancel feeOn-time70%
American AirlinesCheapest$770Average$1,170FlexibilityNo cancel feeOn-time71%
United AirlinesCheapest$930Average$1,252FlexibilityNo cancel feeOn-time69%
DeltaCheapest$1,040Average$1,185FlexibilityNo cancel feeOn-timeN/A

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