Istanbul

$578+ Cheap flights from Knoxville (TYS) to Istanbul

This is the cheapest round-trip flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 3/3. Fares are subject to change and may not be available on all flights or dates of travel.
TYS — IST
Mar 4 — Mar 111
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Cheap flight deals from Knoxville to Istanbul

Cheapest flights from Knoxville to Istanbul
Explore the most affordable flight options available from Knoxville to Istanbul. Find the lowest fares from popular airlines and budget airlines, with prices last updated on February 2, 2026.

This American Airlines deal was found by Cheapflights users on 2/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 3/312:22 pm
TYS
-
IST
2 stops21h 23m
American Airlines
Tue 3/107:35 am
IST
-
TYS
2 stops20h 22m
American Airlines
Deal found 2/1$578
This Lufthansa deal was found by Cheapflights users on 1/31. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Lufthansa is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 3/175:43 pm
TYS
-
IST
2 stops22h 02m
Lufthansa
Tue 3/246:30 am
IST
-
TYS
2 stops21h 17m
Lufthansa
Deal found 1/31$580
This oojo deal was found by Cheapflights users on 2/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure oojo is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 4/107:00 am
TYS
-
IST
2 stops26h 15m
British Airways
Mon 4/138:15 pm
IST
-
TYS
2 stops32h 20m
British Airways
Deal found 2/1$613
This American Airlines deal was found by Cheapflights users on 2/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 3/1911:45 am
TYS
-
IST
2 stops22h 45m
American Airlines
Thu 3/267:35 am
IST
-
TYS
2 stops20h 30m
American Airlines
Deal found 2/2$678
This Air Canada deal was found by Cheapflights users on 2/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Air Canada is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 3/39:40 am
TYS
-
IST
3 stops24h 05m
Air Canada
Tue 3/1011:35 am
IST
-
TYS
3 stops30h 14m
Air Canada
Deal found 2/1$761
This United Airlines deal was found by Cheapflights users on 2/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 2/252:21 pm
TYS
-
IST
2 stops19h 44m
United Airlines
Sun 3/16:30 am
IST
-
TYS
2 stops20h 59m
United Airlines
Deal found 2/1$780
This United Airlines deal was found by Cheapflights users on 2/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 8/192:00 pm
TYS
-
IST
2 stops19h 55m
United Airlines
Fri 9/255:40 am
IST
-
TYS
2 stops40h 02m
United Airlines
Deal found 2/1$831
This KLM deal was found by Cheapflights users on 2/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure KLM is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 3/31:00 pm
TYS
-
SAW
2 stops20h 25m
KLM
Tue 3/109:00 am
SAW
-
TYS
2 stops21h 57m
KLM
Deal found 2/1$881
This KAYAK deal was found by Cheapflights users on 2/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure KAYAK is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 2/21:59 pm
TYS
-
IST
2 stops19h 56m
Lufthansa
Mon 2/96:30 am
IST
-
TYS
2 stops22h 22m
Lufthansa
Deal found 2/1$1,018
This oojo deal was found by Cheapflights users on 1/31. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure oojo is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 5/117:00 am
TYS
-
IST
2 stops28h 55m
British Airways
Sun 5/318:15 am
IST
-
TYS
2 stops19h 06m
British Airways
Deal found 1/31$1,023
This KAYAK deal was found by Cheapflights users on 2/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure KAYAK is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 2/192:21 pm
TYS
-
IST
2 stops19h 44m
Lufthansa
Sat 2/217:00 pm
IST
-
TYS
2 stops33h 37m
Lufthansa
Deal found 2/1$1,038
This American Airlines deal was found by Cheapflights users on 2/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 2/34:00 pm
TYS
-
IST
2 stops17h 45m
American Airlines
Tue 2/107:35 am
IST
-
TYS
2 stops23h 19m
American Airlines
Deal found 2/2$1,048

Find flight deals from Knoxville to Istanbul

Discover tips and strategies to find the most affordable flight options for your journey from Knoxville (TYS) to Istanbul (TR5). Learn about various techniques such as flexible date searches, comparing prices across and setting up price alerts. Use these methods to find the cheapest flights available for your travel needs. Data last updated February 2, 2026.

Round-trip from

$578
(American Airlines)

Popular in

June

Cheapest in

February

Average price

$554
From Knoxville McGhee Tyson to Istanbul
Highest demand for flights based on searches. 23% potential increase in price ($312 potential increase over avg. RT price).
Cheapest flight prices on average. 3% potential price decrease ($41 potential savings vs. average RT price).
Average for round-trip flights in February 2026

Cheapflights Fare Finder

 
Customize your flight search to find flights from Knoxville to Istanbul that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated February 2, 2026.
Use the filters below to find and compare flights from Knoxville to Istanbul that are best for you.

Fly from

Knoxville

Fly to

Istanbul

Route

Depart

Return

Price

KnoxvilleIstanbul

TYS - IST

TYSIST

Knoxville McGhee Tyson

Tue 3/3

12:22 pm-5:45 pm

2 stops21h 23m

Istanbul

Tue 3/10

7:35 am-8:57 pm

2 stops20h 22m

$578

KnoxvilleIstanbul

TYS - IST

TYSIST

Knoxville McGhee Tyson

Tue 3/17

5:43 pm-10:45 pm

2 stops22h 02m

Istanbul

Tue 3/24

6:30 am-8:47 pm

2 stops21h 17m

$580

KnoxvilleIstanbul

TYS - IST

TYSIST

Knoxville McGhee Tyson

Fri 4/10

7:00 am-4:15 pm

2 stops26h 15m

Istanbul

Mon 4/13

8:15 pm-9:35 pm

2 stops32h 20m

$613

KnoxvilleIstanbul

TYS - IST

TYSIST

Knoxville McGhee Tyson

Thu 3/19

11:45 am-5:30 pm

2 stops22h 45m

Istanbul

Thu 3/26

7:35 am-9:05 pm

2 stops20h 30m

$678

KnoxvilleIstanbul

TYS - IST

TYSIST

Knoxville McGhee Tyson

Tue 3/3

9:40 am-5:45 pm

3 stops24h 05m

Istanbul

Tue 3/10

11:35 am-10:49 am

3 stops30h 14m

$761

KnoxvilleIstanbul

TYS - IST

TYSIST

Knoxville McGhee Tyson

Wed 2/25

2:21 pm-6:05 pm

2 stops19h 44m

Istanbul

Sun 3/1

6:30 am-7:29 pm

2 stops20h 59m

$780

KnoxvilleIstanbul

TYS - IST

TYSIST

Knoxville McGhee Tyson

Sun 5/3

7:00 am-1:00 pm

2 stops23h 00m

Istanbul

Sat 5/9

1:55 pm-8:45 pm

2 stops37h 50m

$780

KnoxvilleIstanbul

TYS - SAW

TYSSAW

Knoxville McGhee Tyson

Tue 3/3

1:00 pm-5:25 pm

2 stops20h 25m

Istanbul Sabiha Gokcen

Tue 3/10

9:00 am-11:57 pm

2 stops21h 57m

$881

KnoxvilleIstanbul

TYS - IST

TYSIST

Knoxville McGhee Tyson

Thu 2/19

2:21 pm-6:05 pm

2 stops19h 44m

Istanbul

Sat 2/21

7:00 pm-8:37 pm

2 stops33h 37m

$1,038

KnoxvilleIstanbul

TYS - SAW

TYSSAW

Knoxville McGhee Tyson

Wed 3/18

11:18 am-5:25 pm

2 stops23h 07m

Istanbul Sabiha Gokcen

Sat 3/21

9:00 am-9:06 pm

2 stops19h 06m

$1,065

Flights are sorted by cheapest round-trip flights first.

Deals found on 2/1

Showing 1-10 of 15 results
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Best time to book a flight from Knoxville to Istanbul

Have a flexible travel schedule? Discover the best time to fly to Istanbul from Knoxville with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Knoxville to Istanbul

What is the cheapest month to book a flight from Knoxville to Istanbul?

Currently, February is the cheapest month in which you can book a flight from Knoxville to Istanbul (average of $554). Flying from Knoxville to Istanbul in June is currently the most expensive (average of $1,362). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

Reviews of airlines servicing Istanbul

Get insights into the airlines that provide service to Istanbul. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Istanbul. Reviews last updated February 2, 2026.
Read reviews from past customers who have flown Delta, United Airlines, and American Airlines from Knoxville to Istanbul. Users can see the overall rating for each airline as well as how each is rated in terms of entertainment options, comfort, food, crew/service, and boarding process.

Boarding

8.1

Food

7.2

Comfort

7.9

Entertainment

7.8

Overall

7.9

Crew

8.5

Reviews

1 / 20
6.0
Good

Jim,Nov 2025

AVL - ATL

The exit row seats without a seat in front are great for leg room but don’t have a fold out entertainment console so you’re forced to use the screen several feet in front of you (there is, at least, a remote). Best to bring a tablet loaded with entertainment or a book.

Boarding

8.1

Food

7.2

Comfort

7.9

Entertainment

7.8

Overall

7.9

Crew

8.5

Reviews

1 / 20
6.0
Good

Jim,Nov 2025

AVL - ATL

The exit row seats without a seat in front are great for leg room but don’t have a fold out entertainment console so you’re forced to use the screen several feet in front of you (there is, at least, a remote). Best to bring a tablet loaded with entertainment or a book.

Boarding

8.1

Food

7.2

Comfort

7.9

Entertainment

7.8

Overall

7.9

Crew

8.5

Reviews

1 / 20
6.0
Good

Jim,Nov 2025

AVL - ATL

The exit row seats without a seat in front are great for leg room but don’t have a fold out entertainment console so you’re forced to use the screen several feet in front of you (there is, at least, a remote). Best to bring a tablet loaded with entertainment or a book.

Boarding

8.1

Food

7.2

Comfort

7.9

Entertainment

7.8

Overall

7.9

Crew

8.5

Reviews

1 / 20
6.0
Good

Jim,Nov 2025

AVL - ATL

The exit row seats without a seat in front are great for leg room but don’t have a fold out entertainment console so you’re forced to use the screen several feet in front of you (there is, at least, a remote). Best to bring a tablet loaded with entertainment or a book.

Boarding

8.1

Food

7.2

Comfort

7.9

Entertainment

7.8

Overall

7.9

Crew

8.5

Reviews

1 / 20
6.0
Good

Jim,Nov 2025

AVL - ATL

The exit row seats without a seat in front are great for leg room but don’t have a fold out entertainment console so you’re forced to use the screen several feet in front of you (there is, at least, a remote). Best to bring a tablet loaded with entertainment or a book.

Related info for your journey

Find useful and relevant information for your journey from Knoxville to Istanbul. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.
  • What airport do you fly from for flights from Knoxville to Istanbul?

    If you book a flight to Istanbul from Knoxville, you will be flying from McGhee Tyson, which is the city’s only airport. Knoxville McGhee Tyson (TYS) is located 11.3 mi from the center of Knoxville. There are 0 flights from McGhee Tyson to Istanbul per day from 4 different airlines.

  • How long is the flight from Knoxville to Istanbul?

    American Airlines, Lufthansa, and British Airways can get you from Knoxville to Istanbul in just under 21h 23m. Your travel time can differ by up to 4h 52m. Airlines will cover a distance of 5617 mi. Both multi-stop and nonstop flights can be found to your destination and back.

  • What are the cheapest airlines flying from Knoxville to Istanbul round-trip?

    Our cheapest airline available from Knoxville to Istanbul is British Airways. Our recent data shows that you can find tickets from as low as $758 on this airline. Additional options worth looking into are American Airlines and United Airlines, starting at $770 and $930 round-trip. These flights start at 27% lower than the current average price 3 months from now.

  • Can I find deals for flights from Knoxville to Istanbul that include hotel bookings?

    Yes. In addition to deals on Knoxville to Istanbul flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Knoxville to Istanbul?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Knoxville to Istanbul.

  • Can I find deals for business class flights from Knoxville to Istanbul?

    Yes. Cheapflights offers flight deals from Knoxville to Istanbul by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Knoxville to Istanbul?

    Currently, February is the cheapest month in which you can book a flight from Knoxville to Istanbul (average of $554). Flying from Knoxville to Istanbul in June is currently the most expensive (average of $1,362). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

Browse thousands of different options on Cheapflights for your next trip

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Top 4 airlines flying from Knoxville to Istanbul

Discover the top 4 airlines that operate flights from Knoxville to Istanbul. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated February 2, 2026.
AirlineCheapestAverageFlexibilityOn-time
British AirwaysCheapest$758Average$1,071FlexibilityNo cancel feeOn-time70%
American AirlinesCheapest$770Average$1,102FlexibilityNo cancel feeOn-time71%
United AirlinesCheapest$930Average$1,208FlexibilityNo cancel feeOn-time69%
DeltaCheapest$1,061Average$1,316FlexibilityNo cancel feeOn-timeN/A

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