$425+ Cheap flights from San Antonio (SAT) to Guayaquil (GYE)
This is the cheapest round-trip flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 12/14. Fares are subject to change and may not be available on all flights or dates of travel.
SAT — GYE
Oct 8 — Oct 151
Round-trip
1 adult, Economy
We work with more than 300 partners to bring you better travel deals
Find cheap flights from San Antonio to Guayaquil with Cheapflights
1. Tell us where you want to go
Enter your travel information like dates, passengers, trip type (one-way or round trip), and preferred cabin class then click “Find deals”2. Select your favorite providers
We find the providers serving your travel needs. Choose up to four travel providers to compare side-by-side for flights, hotels, or car rentals.3. Compare prices and book
Review each provider’s pricing and select the best option for you! Book through your favorite provider’s website for a seamless experience.Cheap flight deals from San Antonio to Guayaquil
Cheapest
Best
Last-minute
One-way
Cheapest flights from San Antonio to GuayaquilExplore the most affordable flight options available from San Antonio to Guayaquil. Find the lowest fares from popular airlines and budget airlines, with prices last updated on September 8, 2026.
Explore the most affordable flight options available from San Antonio to Guayaquil. Find the lowest fares from popular airlines and budget airlines, with prices last updated on September 8, 2026.
This United deal was found by Cheapflights users on 9/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/85:30 am -
2 stops18h 07m
Sat 10/176:50 pm -
2 stops14h 02m
Deal found 9/7![Multiple Airlines logo]()
$819
This Ovago deal was found by Cheapflights users on 9/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Ovago is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 10/245:58 pm -
2 stops29h 39m
Sat 10/3112:23 pm -
2 stops10h 28m
Deal found 9/8![Copa Airlines logo]()
$880
This American Airlines deal was found by Cheapflights users on 9/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/85:10 am -
1 stop17h 29m
Sat 10/176:00 am -
1 stop15h 59m
Deal found 9/7![American Airlines logo]()
$892
This United Airlines deal was found by Cheapflights users on 9/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 11/65:30 am -
2 stops17h 10m
Wed 11/1112:24 pm -
2 stops30h 41m
Deal found 9/7![United Airlines logo]()
$993
This United Airlines deal was found by Cheapflights users on 9/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 11/55:57 pm -
2 stops28h 43m
Wed 11/118:27 am -
2 stops25h 02m
Deal found 9/7![United Airlines logo]()
$1,000
This American Airlines deal was found by Cheapflights users on 9/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 12/145:00 am -
1 stop8h 31m
Mon 12/286:00 am -
1 stop18h 13m
Deal found 9/8![American Airlines logo]()
$1,009
This American Airlines deal was found by Cheapflights users on 9/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 10/245:43 pm -
2 stops19h 46m
Sat 10/316:00 am -
1 stop15h 59m
Deal found 9/8![American Airlines logo]()
$1,034
Best flights from San Antonio to GuayaquilDiscover carefully curated flight deals from San Antonio to Guayaquil that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated September 8, 2026.
Discover carefully curated flight deals from San Antonio to Guayaquil that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated September 8, 2026.
This United deal was found by Cheapflights users on 9/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/85:30 am -
2 stops18h 07m
Sat 10/176:50 pm -
2 stops14h 02m
Deal found 9/7![Multiple Airlines logo]()
$819
This Ovago deal was found by Cheapflights users on 9/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Ovago is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 10/245:58 pm -
2 stops29h 39m
Sat 10/3112:23 pm -
2 stops10h 28m
Deal found 9/8![Copa Airlines logo]()
$880
This United Airlines deal was found by Cheapflights users on 9/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 1/305:30 am -
2 stops17h 13m
Wed 2/38:26 am -
2 stops12h 04m
Deal found 9/8![United Airlines logo]()
$993
This American Airlines deal was found by Cheapflights users on 9/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 10/245:43 pm -
2 stops19h 46m
Sat 10/316:00 am -
1 stop15h 59m
Deal found 9/8![American Airlines logo]()
$1,034
This United Airlines deal was found by Cheapflights users on 9/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 11/95:30 am -
2 stops14h 26m
Sun 11/1512:24 pm -
2 stops11h 27m
Deal found 9/7![United Airlines logo]()
$993
This United Airlines deal was found by Cheapflights users on 9/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 11/55:57 pm -
2 stops28h 43m
Wed 11/118:27 am -
2 stops25h 02m
Deal found 9/7![United Airlines logo]()
$1,000
This Mytrip deal was found by Cheapflights users on 9/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Mytrip is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 10/2412:41 pm -
2 stops20h 19m
Fri 10/303:18 am -
3 stops32h 55m
Deal found 9/8![Multiple Airlines logo]()
$1,421
Last-minute flights from San Antonio to GuayaquilDiscover last-minute flight deals from San Antonio to Guayaquil. Data last updated September 8, 2026 and is based on user searches.
Discover last-minute flight deals from San Antonio to Guayaquil. Data last updated September 8, 2026 and is based on user searches.
This United deal was found by Cheapflights users on 9/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/85:30 am -
2 stops18h 07m
Sat 10/176:50 pm -
2 stops14h 02m
Deal found 9/7![Multiple Airlines logo]()
$819
This American Airlines deal was found by Cheapflights users on 9/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/85:10 am -
1 stop17h 29m
Sat 10/176:00 am -
1 stop15h 59m
Deal found 9/7![American Airlines logo]()
$892
This Ovago deal was found by Cheapflights users on 9/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Ovago is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 10/245:58 pm -
2 stops29h 39m
Sat 10/3112:23 pm -
2 stops10h 28m
Deal found 9/8![Copa Airlines logo]()
$880
This American Airlines deal was found by Cheapflights users on 9/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 10/245:43 pm -
2 stops19h 46m
Sat 10/316:00 am -
1 stop15h 59m
Deal found 9/8![American Airlines logo]()
$1,034
This Mytrip deal was found by Cheapflights users on 9/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Mytrip is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 10/2412:41 pm -
2 stops20h 19m
Fri 10/303:18 am -
3 stops32h 55m
Deal found 9/8![Multiple Airlines logo]()
$1,421
One-way flights from San Antonio to GuayaquilSearch for one-way flight options from San Antonio to Guayaquil. Find affordable one-way fares based on user searches. Data last updated September 8, 2026.
Search for one-way flight options from San Antonio to Guayaquil. Find affordable one-way fares based on user searches. Data last updated September 8, 2026.
This Kiwi.com deal was found by Cheapflights users on 9/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 12/1411:00 am -
3 stops25h 42m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 9/7![Multiple Airlines logo]()
$425
This United Airlines deal was found by Cheapflights users on 9/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 9/219:30 am -
2 stops32h 00m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 9/5![United Airlines logo]()
$510
This United Airlines deal was found by Cheapflights users on 9/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 9/207:35 am -
2 stops33h 55m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 9/5![United Airlines logo]()
$520
This KAYAK deal was found by Cheapflights users on 9/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure KAYAK is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 1/510:00 am -
2 stops12h 58m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 9/4![Copa Airlines logo]()
$539
This American Airlines deal was found by Cheapflights users on 9/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 12/145:00 am -
1 stop8h 31m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 9/7![American Airlines logo]()
$617
This American Airlines deal was found by Cheapflights users on 9/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 1/55:08 am -
1 stop17h 47m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 9/3![American Airlines logo]()
$625
This United Airlines deal was found by Cheapflights users on 9/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 1/57:30 am -
3 stops36h 29m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 9/6![United Airlines logo]()
$2,490
Find flight deals from San Antonio to Guayaquil
Discover tips and strategies to find the most affordable flight options for your journey from San Antonio (SAT) to Guayaquil (GYE). Learn about various techniques such as flexible date searches, comparing prices across and setting up price alerts. Use these methods to find the cheapest flights available for your travel needs. Data last updated September 8, 2026.
Most accurate provider | Ovago 3 stars |
|---|---|
Most trusted provider | Ovago 3 stars |
Round-trip from | $819 (United) |
One-way from | $425 (Kiwi.com) |
Cheapflights Fare Finder
Customize your flight search to find flights from San Antonio to Guayaquil that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 7,457,451 searches. Data last updated September 8, 2026.
Use the filters below to find and compare flights from San Antonio to Guayaquil that are best for you.
Fly from
Fly to
Route
Depart
Return
Cheapest round-trip
San AntonioGuayaquil
SAT San Antonio - GYE Guayaquil Jose Joaquin de Olmedo
SATGYE
San Antonio
Mon 9/21
9:30 am-5:30 pm
2 stops32h 00m
Guayaquil Jose Joaquin de Olmedo
Wed 12/31
12:00 am-11:00 pm
Nonstop0h 00m
$510
San AntonioGuayaquil
SAT San Antonio - GYE Guayaquil Jose Joaquin de Olmedo
SATGYE
San Antonio
Sun 9/20
7:35 am-5:30 pm
2 stops33h 55m
Guayaquil Jose Joaquin de Olmedo
Wed 12/31
12:00 am-11:00 pm
Nonstop0h 00m
$520
San AntonioGuayaquil
SAT San Antonio - GYE Guayaquil Jose Joaquin de Olmedo
SATGYE
San Antonio
Tue 1/5
10:00 am-11:58 pm
2 stops12h 58m
Guayaquil Jose Joaquin de Olmedo
Wed 12/31
12:00 am-11:00 pm
Nonstop0h 00m
$539
San AntonioGuayaquil
SAT San Antonio - GYE Guayaquil Jose Joaquin de Olmedo
SATGYE
San Antonio
Mon 12/14
7:30 pm-9:00 am
2 stops36h 30m
Guayaquil Jose Joaquin de Olmedo
Wed 12/31
12:00 am-11:00 pm
Nonstop0h 00m
$607
Quickest round-trip
San AntonioGuayaquil
SAT San Antonio - GYE Guayaquil Jose Joaquin de Olmedo
SATGYE
San Antonio
Mon 12/14
5:00 am-2:31 pm
1 stop8h 31m
Guayaquil Jose Joaquin de Olmedo
Wed 12/31
12:00 am-11:00 pm
Nonstop0h 00m
$617
San AntonioGuayaquil
SAT San Antonio - GYE Guayaquil Jose Joaquin de Olmedo
SATGYE
San Antonio
Tue 1/5
5:08 am-11:55 pm
1 stop17h 47m
Guayaquil Jose Joaquin de Olmedo
Wed 12/31
12:00 am-11:00 pm
Nonstop0h 00m
$625
San AntonioGuayaquil
SAT San Antonio - GYE Guayaquil Jose Joaquin de Olmedo
SATGYE
San Antonio
Thu 10/8
5:30 am-11:37 pm
2 stops18h 07m
Guayaquil Jose Joaquin de Olmedo
Sat 10/17
6:50 pm-8:52 am
2 stops14h 02m
$819
San AntonioGuayaquil
SAT San Antonio - GYE Guayaquil Jose Joaquin de Olmedo
SATGYE
San Antonio
Sat 10/24
5:58 pm-11:37 pm
2 stops29h 39m
Guayaquil Jose Joaquin de Olmedo
Sat 10/31
12:23 pm-10:51 pm
2 stops10h 28m
$880
San AntonioGuayaquil
SAT San Antonio - GYE Guayaquil Jose Joaquin de Olmedo
SATGYE
San Antonio
Sat 1/30
5:30 am-11:43 pm
2 stops17h 13m
Guayaquil Jose Joaquin de Olmedo
Wed 2/3
8:26 am-7:30 pm
2 stops12h 04m
$993
San AntonioGuayaquil
SAT San Antonio - GYE Guayaquil Jose Joaquin de Olmedo
SATGYE
San Antonio
Mon 11/9
5:30 am-8:56 pm
2 stops14h 26m
Guayaquil Jose Joaquin de Olmedo
Sun 11/15
12:24 pm-10:51 pm
2 stops11h 27m
$993
Showing 1-10 of 13 resultsSorted by cheapest first
Compare providers for flights from San Antonio to Guayaquil
Provider information is updated monthly. Please note that these providers often have deals for this flight, but the availability may vary on a day-by-day basis on Cheapflights.
Use the table below to compare price accuracy, trust ratings, and cancellation policies for each provider offering flight deals from San Antonio to Guayaquil in September.
| Provider | Price Accuracy | Trust Score* |
|---|---|---|
| Price Accuracy1 star | Trust Score*3 stars | |
| Price Accuracy3 stars | Trust Score*3 stars | |
| Price Accuracy3 stars | Trust Score*3 stars | |
| Price Accuracy3 stars | Trust Score*3 stars |
- Most accurate provider: When it comes to deals on San Antonio-Guayaquil flights, users find the pricing of Ovago to be most consistent on Cheapflights vs. Ovago Users can find the same prices on San Antonio-Guayaquil flight deals on Cheapflights vs. Ovago >95% of the time. Price accuracy is based on data collected from San Antonio-Guayaquil flight searches over the past month and is updated monthly.
- Most trusted provider: When it comes to deals on San Antonio-Guayaquil flights, Cheapflights users trust Ovago the most. Ovago has received a user feedback score of 3 out of 3 stars (3 being the best), meaning they have been trusted the most by Cheapflights users looking for San Antonio-Guayaquil flight deals. Provider user feedback score is based on Cheapflights searches over the past month and is updated monthly.
Best time to book a flight from San Antonio to Guayaquil
Have a flexible travel schedule? Discover the best time to fly to Guayaquil from San Antonio with our price prediction graph.
SAT-GYE
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.
Reviews of airlines servicing Guayaquil
Get insights into the airlines that provide service to Guayaquil. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Guayaquil. Reviews last updated September 8, 2026.
Get a feel of what it's like to fly with Copa Airlines from San Antonio to Guayaquil by reading reviews from past customers. Users have also rated airlines in terms of entertainment options, comfort, food, crew/service, and boarding process.
Entertainment
6.9
Overall
7.6
Crew
8.1
Comfort
7.4
Food
6.9
Boarding
7.8
Reviews
1 / 20
2.0
MediocreAnonymous,Jul 2026
BOS - PTY
Entertainment
6.9
Overall
7.6
Crew
8.1
Comfort
7.4
Food
6.9
Boarding
7.8
Reviews
1 / 20
2.0
MediocreAnonymous,Jul 2026
BOS - PTY
Related info for your journey
Find useful and relevant information for your journey from San Antonio to Guayaquil. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.
Browse thousands of different options on Cheapflights for your next trip
Toggle through the tabs below to find thousands of options on Cheapflights for your next trip.
Alternative routes
Complete your trip
Flights by cabin class
Guayaquil flight routes
Other flight options
Other flights from San Antonio
Popular flights
Alternative routes for San Antonio to Guayaquil
See prices for flight routes from nearby airports that may be better suited for you.
Complete your trip
Complete your trip to Guayaquil by adding a car rental and/or hotel reservation to your travel itinerary.
Search flights from San Antonio to Guayaquil by cabin class
Find flights from San Antonio to Guayaquil, based on your preferred cabin class, be it economy, premium economy, business, or first class.
Other flights to Guayaquil
Explore flights to Guayaquil departing from other origins. Flights are based on user searches made on Cheapflights and were last updated on September 8, 2026.
San Antonio and Guayaquil flights
Browse other San Antonio and Guayaquil flight options. Last updated on September 8, 2026.
Other flights from San Antonio
Browse through other flights departing from San Antonio. Flights are based on user searches made on Cheapflights and were last updated on September 8, 2026.
Popular flight searches
Check out other popular destinations found by fellow travelers in 2026
Top airline flying from San Antonio to Guayaquil
Discover the top airline that operate flights from San Antonio to Guayaquil. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 7,457,451 searches. Data last updated September 8, 2026.
| Airline | Cheapest | Average | Flexibility | On-time |
|---|---|---|---|---|
| Cheapest$703 | Average$703 | FlexibilityNo cancel fee | On-time70% |