HomeSearch by dateVacation packagesHotelsFlight dealsCar rentalTravel tips & news
Guayaquil

$161+ Cheap flights from Ohio to Guayaquil (GYE)

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 10/1. Fares are subject to change and may not be available on all flights or dates of travel.
CVG — GYE
Oct 11 — Oct 181
Sat 10/11
Sat 10/18
1 adult, Economy
We work with more than 300 partners to bring you better travel deals

Find cheap flights from Ohio to Guayaquil with Cheapflights

1. Tell us where you want to go

Enter your travel information like dates, passengers, trip type (one-way or round trip), and preferred cabin class then click “Find deals”

2. Select your favorite providers

We find the providers serving your travel needs. Choose up to four travel providers to compare side-by-side for flights, hotels, or car rentals.

3. Compare prices and book

Review each provider’s pricing and select the best option for you! Book through your favorite provider’s website for a seamless experience.

Cheap flight deals from Ohio to Guayaquil

Keep the following information in mind while searching for Ohio to Guayaquil flight deals. Data was last updated September 11, 2025.

Round-trip from

$407
(Avianca Connect)

One-way from

$161
(Kiwi.com)
From Ohio to Guayaquil Jose Joaquin de Olmedo
Search Deals
One-way flight from Ohio to Guayaquil Jose Joaquin de Olmedo
Search Deals

Find flight deals from Ohio to Guayaquil

Cheapest flights from Ohio to Guayaquil
Explore the most affordable flight options available from Ohio to Guayaquil. Find the lowest fares from popular airlines and budget airlines, with prices last updated on September 11, 2025.

This Avianca Connect deal was found by Cheapflights users on 9/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Avianca Connect is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 11/117:00 amDTW - GYE
1 stop22h 35mMultiple Airlines
Wed 11/196:50 pmGYE - DTW
1 stop19h 19mMultiple Airlines
Deal found 9/10$407
This Avianca Connect deal was found by Cheapflights users on 9/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Avianca Connect is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 11/107:00 amDTW - GYE
1 stop22h 20mMultiple Airlines
Wed 11/196:50 pmGYE - DTW
1 stop19h 19mMultiple Airlines
Deal found 9/10$427
This Avianca Connect deal was found by Cheapflights users on 9/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Avianca Connect is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 10/216:43 amDTW - GYE
2 stops17h 37mMultiple Airlines
Thu 10/304:40 amGYE - DTW
2 stops18h 40mMultiple Airlines
Deal found 9/10$440
This Expedia deal was found by Cheapflights users on 9/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Expedia is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 11/112:31 pmDTW - GYE
2 stops23h 49mJetBlue
Wed 11/193:30 pmGYE - DTW
2 stops31h 27mJetBlue
Deal found 9/10$545
This Expedia deal was found by Cheapflights users on 9/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Expedia is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 10/2212:16 pmDTW - GYE
2 stops26h 14mJetBlue
Fri 10/316:20 amGYE - DTW
1 stop15h 21mJetBlue
Deal found 9/10$588
This Mytrip deal was found by Cheapflights users on 9/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Mytrip is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/316:21 pmCMH - GYE
3 stops45h 09mMultiple Airlines
Wed 11/56:55 pmGYE - CMH
2 stops26h 17mMultiple Airlines
Deal found 9/11$590
This Expedia deal was found by Cheapflights users on 9/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Expedia is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 10/216:00 amDTW - GYE
1 stop13h 51mJetBlue
Thu 10/306:20 amGYE - DTW
1 stop15h 37mJetBlue
Deal found 9/10$594
This Expedia deal was found by Cheapflights users on 9/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Expedia is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 10/2212:16 pmDTW - GYE
2 stops26h 14mJetBlue
Sat 11/16:20 amGYE - DTW
1 stop15h 37mJetBlue
Deal found 9/10$602
This United Airlines deal was found by Cheapflights users on 9/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 11/284:45 pmCMH - GYE
2 stops30h 56mUnited Airlines
Sun 12/78:30 amGYE - CMH
2 stops13h 59mUnited Airlines
Deal found 9/10$656
This United Airlines deal was found by Cheapflights users on 9/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/166:15 amCMH - GYE
2 stops30h 00mUnited Airlines
Sat 10/258:30 amGYE - CMH
2 stops25h 25mUnited Airlines
Deal found 9/11$683
This United Airlines deal was found by Cheapflights users on 9/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/175:00 pmCMH - GYE
2 stops31h 37mUnited Airlines
Sat 10/258:30 amGYE - CMH
2 stops25h 25mUnited Airlines
Deal found 9/11$705
This United Airlines deal was found by Cheapflights users on 9/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/316:30 amCMH - GYE
2 stops29h 48mUnited Airlines
Wed 11/512:21 pmGYE - CMH
2 stops33h 51mUnited Airlines
Deal found 9/11$753

Cheapflights Fare Finder

 
Customize your flight search to find flights from Ohio to Guayaquil that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated September 11, 2025.
Use the filters below to find and compare flights from Ohio to Guayaquil that are best for you.

Fly from

Ohio

Fly to

Guayaquil

Route

Depart

Return

Price

DetroitGuayaquil

DTW - GYE

DTWGYE

Detroit Metropolitan Wayne County

Tue 11/11

7:00 am-5:35 am

1 stop22h 35m

Guayaquil Jose Joaquin de Olmedo

Wed 11/19

6:50 pm-2:09 pm

1 stop19h 19m

$407

DetroitGuayaquil

DTW - GYE

DTWGYE

Detroit Metropolitan Wayne County

Mon 11/10

7:00 am-5:20 am

1 stop22h 20m

Guayaquil Jose Joaquin de Olmedo

Wed 11/19

6:50 pm-2:09 pm

1 stop19h 19m

$427

DetroitGuayaquil

DTW - GYE

DTWGYE

Detroit Metropolitan Wayne County

Tue 10/21

6:43 am-11:20 pm

2 stops17h 37m

Guayaquil Jose Joaquin de Olmedo

Thu 10/30

4:40 am-12:20 am

2 stops18h 40m

$440

ClevelandGuayaquil

CLE - GYE

CLEGYE

Cleveland Hopkins Intl

Fri 1/23

12:15 pm-11:45 pm

1 stop11h 30m

Guayaquil Jose Joaquin de Olmedo

Fri 1/30

12:59 am-11:20 am

1 stop10h 21m

$473

DetroitGuayaquil

DTW - GYE

DTWGYE

Detroit Metropolitan Wayne County

Tue 11/11

2:31 pm-2:20 pm

2 stops23h 49m

Guayaquil Jose Joaquin de Olmedo

Wed 11/19

3:30 pm-10:57 pm

2 stops31h 27m

$545

ClevelandGuayaquil

CLE - GYE

CLEGYE

Cleveland Hopkins Intl

Fri 1/23

5:23 am-10:05 pm

2 stops16h 42m

Guayaquil Jose Joaquin de Olmedo

Sat 1/31

7:30 am-4:36 pm

1 stop9h 06m

$579

ColumbusGuayaquil

CMH - GYE

CMHGYE

Columbus

Fri 10/31

6:21 pm-2:30 pm

3 stops45h 09m

Guayaquil Jose Joaquin de Olmedo

Wed 11/5

6:55 pm-9:12 pm

2 stops26h 17m

$590

ClevelandGuayaquil

CLE - GYE

CLEGYE

Cleveland Hopkins Intl

Fri 1/23

12:15 pm-11:45 pm

1 stop11h 30m

Guayaquil Jose Joaquin de Olmedo

Fri 1/30

12:59 am-12:26 am

2 stops23h 27m

$633

DetroitGuayaquil

DTW - GYE

DTWGYE

Detroit Metropolitan Wayne County

Mon 11/10

6:00 am-11:06 pm

2 stops17h 06m

Guayaquil Jose Joaquin de Olmedo

Wed 11/19

6:00 am-9:48 am

2 stops27h 48m

$643

DetroitGuayaquil

DTW - GYE

DTWGYE

Detroit Metropolitan Wayne County

Wed 10/22

6:00 am-6:51 pm

1 stop13h 51m

Guayaquil Jose Joaquin de Olmedo

Fri 10/31

6:20 am-10:41 pm

1 stop15h 21m

$653

Flights are sorted by cheapest round-trip flights first.

Deals found on 9/11

Showing 1-10 of 32 results
1
2
3
4

Best time to book a flight from Ohio to Guayaquil

Have a flexible travel schedule? Discover the best time to fly to Guayaquil from Ohio with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Ohio to Guayaquil

What is the cheapest month to book a flight from Ohio to Guayaquil?

Currently, April is the cheapest month in which you can book a flight from Ohio to Guayaquil (average of $440). Flying from Ohio to Guayaquil in December is currently the most expensive (average of $722). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

What is the cheapest time of day to fly from OH to GYE?

Find hourly flight availability from Ohio to Guayaquil. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated September 11, 2025.

Regardless of the time of day you decide to fly, the ticket price will remain around the same. Book flights from Ohio to Guayaquil as you normally would.

Related info for your journey

Find useful and relevant information for your journey from Ohio to Guayaquil. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • What airport do you fly into for flights to Guayaquil from Ohio?

    Guayaquil Jose Joaquin de Olmedo (GYE), located 2.5 mi from the city center, is the airport you fly into when you book flights from Ohio to Guayaquil.

  • How long is the flight from Ohio to Guayaquil?

    Spirit Airlines, American Airlines, and United Airlines can get you from Ohio to Guayaquil in just under 11h 30m. Your travel time can differ by up to 19h 26m. There are 3011 mi between Ohio and Guayaquil. When browsing for deals, the options you’ll see will be for both nonstop flights and flights with stops.

  • What are the cheapest airlines to fly from Ohio to Guayaquil one-way?

    One-way options have recently been found by users for as low as $344 on Spirit Airlines. Other airlines that offer cheap prices include American Airlines from $386 and United Airlines from $400 one-way.

  • What are the most popular routes from Ohio to Guayaquil?

    When deciding which route to take from Ohio to Guayaquil consider Columbus - Guayaquil Jose Joaquin de Olmedo, Detroit Metropolitan Wayne County - Guayaquil Jose Joaquin de Olmedo or Cincinnati Cinci./N. Kentucky - Guayaquil Jose Joaquin de Olmedo as they are the most popular.

  • Can I find deals for flights from Ohio to Guayaquil that include hotel bookings?

    Yes. In addition to deals on Ohio to Guayaquil flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Ohio to Guayaquil?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Ohio to Guayaquil.

  • Can I find deals for business class flights from Ohio to Guayaquil?

    Yes. Cheapflights offers flight deals from Ohio to Guayaquil by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Ohio to Guayaquil?

    Currently, April is the cheapest month in which you can book a flight from Ohio to Guayaquil (average of $440). Flying from Ohio to Guayaquil in December is currently the most expensive (average of $722). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

Browse thousands of different options on Cheapflights for your next trip

Toggle through the tabs below to find thousands of options on Cheapflights for your next trip.

Alternative routes for Ohio to Guayaquil

See prices for flight routes from nearby airports that may be better suited for you.
John F Kennedy Intl to Guayaquil flights
John F Kennedy Intl to Quito flights
Newark to Guayaquil flights
Newark to Quito flights
LaGuardia to Guayaquil flights
LaGuardia to Quito flights
Miami to Quito flights
Fort Lauderdale to Guayaquil flights
San Francisco to Quito flights
Miami to Guayaquil flights
Atlanta to Quito flights
Dulles Intl to Quito flights
Hobby to Quito flights
Seattle to Quito flights
O'Hare Intl to Quito flights
George Bush Intcntl to Quito flights
Dallas/Fort Worth to Quito flights
Los Angeles to Quito flights
Midway to Quito flights
O'Hare Intl to Guayaquil flights
Fort Lauderdale to Quito flights
John F Kennedy Intl to Cuenca flights
Hobby to Guayaquil flights
Dulles Intl to Guayaquil flights
Baltimore to Quito flights
Denver to Quito flights
Orlando to Guayaquil flights
Reagan-National to Quito flights
Raleigh to Quito flights
Boston to Quito flights
Boston to Guayaquil flights
Minneapolis to Quito flights
George Bush Intcntl to Guayaquil flights
Austin to Quito flights
Baltimore to Guayaquil flights
Orlando to Quito flights
Tampa to Quito flights
John F Kennedy Intl to Manta flights
LaGuardia to Cuenca flights
Reagan-National to Guayaquil flights
Philadelphia to Quito flights
Salt Lake City to Quito flights
Indianapolis to Quito flights
Ontario to Quito flights
San Diego to Quito flights
San Francisco to Guayaquil flights
Charlotte to Quito flights
Newark to Cuenca flights
Atlanta to Guayaquil flights
Tampa to Guayaquil flights

Top airline flying from Ohio to Guayaquil

Discover the top airline that operate flights from Ohio to Guayaquil. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated September 11, 2025.
AirlineCheapestAverageFlexibilityOn-time
American AirlinesCheapest$521Average$756FlexibilityNo cancel feeOn-time71%

100% Free

Cheapflights is completely free to use, so you can start saving the moment you arrive.

Book with Flexibility

Our users can plan ahead with confidence and find flights with no change fees

Travel Smart

Millions of people come to us for their flight needs every year. We help make travel planning easy by providing useful insights and data-driven graphs that can inform your decisions.