What is the cheapest month to book a flight from Panama City, Florida to Guayaquil?

Currently, April is the cheapest month in which you can book a flight from Panama City, Florida to Guayaquil (average of $440). Flying from Panama City, Florida to Guayaquil in December is currently the most expensive (average of $722). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

In terms of precipitation, rainfall in Guayaquil ranges from 0.0 - 11.0 inches per month. March is typically the wettest month, when rainfall can reach 11.0 in. July is typically the driest time to visit Guayaquil when rainfall is around 0.0 in.

If weather is an important factor for your trip to Guayaquil, use this chart to help with planning. For those seeking warmer temperatures, January is the ideal time of year to visit, when temperatures reach an average of 80.6 F. Travelers looking to avoid the cold should look outside of June, when temperatures are typically at their lowest (around 77.0 F).

What is the cheapest time of day to fly from ECP to GYE?

Regardless of the time of day you decide to fly, the ticket price will remain around the same. Book flights from Panama City, Florida to Guayaquil as you normally would.

Can I find deals for flights from Panama City to Guayaquil that include hotel bookings?

Yes. In addition to deals on Panama City to Guayaquil flights, Cheapflights offers vacation packages that include both flights and hotel.

How can I find direct flights from Panama City to Guayaquil?

After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Panama City to Guayaquil.

Can I find deals for business class flights from Panama City to Guayaquil?

Yes. Cheapflights offers flight deals from Panama City to Guayaquil by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

$377+ Flights from Panama City, FL to Guayaquil

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Cheap flight deals from Panama City to Guayaquil

Round-trip from	$632 (United Airlines)
One-way from	$377 (Delta)

From Panama City NW Florida Beaches to Guayaquil Jose Joaquin de Olmedo

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One-way flight from Panama City NW Florida Beaches to Guayaquil Jose Joaquin de Olmedo

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Find flight deals from Panama City to Guayaquil

Cheapest flights from Panama City to Guayaquil
Explore the most affordable flight options available from Panama City to Guayaquil. Find the lowest fares from popular airlines and budget airlines, with prices last updated on August 11, 2025.

Fri 10/36:30 amECP - GYE

2 stops31h 16mUnited Airlines

Tue 10/712:15 pmGYE - ECP

2 stops33h 33mUnited Airlines

Deal found 8/10

$632

Best flights from Panama City to Guayaquil
Discover carefully curated flight deals from Panama City to Guayaquil that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated August 11, 2025.

Fri 10/36:30 amECP - GYE

2 stops31h 16mUnited Airlines

Tue 10/712:15 pmGYE - ECP

2 stops33h 33mUnited Airlines

Deal found 8/10

$632

One-way flights from Panama City to Guayaquil
Search for one-way flight options from Panama City to Guayaquil. Find affordable one-way fares based on user searches. Data last updated August 11, 2025.

Thu 1/16:00 amECP - GYE

2 stops19h 05mDelta

Deal found 8/11

$377

Cheapflights Fare Finder

Use the filters below to find and compare flights from Panama City to Guayaquil that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

Panama CityGuayaquil

ECP - GYE

ECPGYE

Panama City NW Florida Beaches

Fri 10/3

6:30 am-1:46 pm

2 stops31h 16m

Guayaquil Jose Joaquin de Olmedo

Tue 10/7

12:15 pm-9:48 pm

2 stops33h 33m

$632

Panama CityGuayaquil

ECP - GYE

ECPGYE

Panama City NW Florida Beaches

Thu 1/1

6:00 am-2:05 am

2 stops19h 05m

$377

Flights are sorted by cheapest round-trip flights first.

Deals found on 8/11

Best time to book a flight from Panama City to Guayaquil

Have a flexible travel schedule? Discover the best time to fly to Guayaquil from Panama City with our price prediction graph.

Estimated round-trip price

Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Reviews of airlines servicing Guayaquil

Peruse reviews from past customers who have flown with Delta and United Airlines from Panama City to Guayaquil to help guide your decision. You can also see how each airline stacks up in terms of entertainment options, comfort, food, crew/service, and boarding process.

Delta

8.0

Very good

7,979 reviews

Reviews

1 / 20

6.0

Good

pilar,May 2025

RSW - ATL

The stewardess was not very nice because I requested two glasses of water. She didn’t even offer the snacks to me. She seemed angry and I felt very bad about her reaction. Also, the flight was full and you could not move. The airline should provide seats for obese people in consideration to the rest pf the passengers.

Delta

8.0

Very good

7,979 reviews

Delta

8.0

Very good

7,979 reviews

Reviews

1 / 20

6.0

Good

pilar,May 2025

RSW - ATL

United Airlines

7.4

Good

8,920 reviews

Delta

8.0

Very good

7,979 reviews

Reviews

1 / 20

6.0

Good

pilar,May 2025

RSW - ATL

Related info for your journey

Can I find deals for flights from Panama City to Guayaquil that include hotel bookings?
Yes. In addition to deals on Panama City to Guayaquil flights, Cheapflights offers vacation packages that include both flights and hotel.
How can I find direct flights from Panama City to Guayaquil?
After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Panama City to Guayaquil.
Can I find deals for business class flights from Panama City to Guayaquil?
Yes. Cheapflights offers flight deals from Panama City to Guayaquil by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.
What is the cheapest month to book a flight from Panama City, Florida to Guayaquil?
Currently, April is the cheapest month in which you can book a flight from Panama City, Florida to Guayaquil (average of $440). Flying from Panama City, Florida to Guayaquil in December is currently the most expensive (average of $722). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

Browse thousands of different options on Cheapflights for your next trip

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$377+ Cheap flights from Panama City, FL (ECP) to Guayaquil (GYE)

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 1/1. Fares are subject to change and may not be available on all flights or dates of travel.

Find cheap flights from Panama City to Guayaquil with Cheapflights

1. Tell us where you want to go

2. Select your favorite providers

3. Compare prices and book

Cheap flight deals from Panama City to Guayaquil

Round-trip from

One-way from

Find flight deals from Panama City to Guayaquil

Cheapest flights from Panama City to GuayaquilExplore the most affordable flight options available from Panama City to Guayaquil. Find the lowest fares from popular airlines and budget airlines, with prices last updated on August 11, 2025.

Explore the most affordable flight options available from Panama City to Guayaquil. Find the lowest fares from popular airlines and budget airlines, with prices last updated on August 11, 2025.

Cheapflights Fare Finder

Use the filters below to find and compare flights from Panama City to Guayaquil that are best for you.

Best time to book a flight from Panama City to Guayaquil

Have a flexible travel schedule? Discover the best time to fly to Guayaquil from Panama City with our price prediction graph.

Reviews of airlines servicing Guayaquil

Peruse reviews from past customers who have flown with Delta and United Airlines from Panama City to Guayaquil to help guide your decision. You can also see how each airline stacks up in terms of entertainment options, comfort, food, crew/service, and boarding process.

Related info for your journey

Find useful and relevant information for your journey from Panama City to Guayaquil. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

Can I find deals for flights from Panama City to Guayaquil that include hotel bookings?

How can I find direct flights from Panama City to Guayaquil?

Can I find deals for business class flights from Panama City to Guayaquil?

What is the cheapest month to book a flight from Panama City, Florida to Guayaquil?

Browse thousands of different options on Cheapflights for your next trip

Toggle through the tabs below to find thousands of options on Cheapflights for your next trip.

Alternative routes for Panama City to Guayaquil

See prices for flight routes from nearby airports that may be better suited for you.

100% Free

Book with Flexibility

Travel Smart

Cheapest flights from Panama City to Guayaquil
Explore the most affordable flight options available from Panama City to Guayaquil. Find the lowest fares from popular airlines and budget airlines, with prices last updated on August 11, 2025.