HomeSearch by dateVacation packagesHotelsFlight dealsCar rentalTravel tips & news
Guayaquil

$122+ Cheap flights from North Carolina to Guayaquil (GYE)

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 12/23. Fares are subject to change and may not be available on all flights or dates of travel.
RDU — GYE
Dec 6 — Dec 131
Sat 12/6
Sat 12/13
1 adult, Economy
We work with more than 300 partners to bring you better travel deals

Find cheap flights from North Carolina to Guayaquil with Cheapflights

1. Tell us where you want to go

Enter your travel information like dates, passengers, trip type (one-way or round trip), and preferred cabin class then click “Find deals”

2. Select your favorite providers

We find the providers serving your travel needs. Choose up to four travel providers to compare side-by-side for flights, hotels, or car rentals.

3. Compare prices and book

Review each provider’s pricing and select the best option for you! Book through your favorite provider’s website for a seamless experience.

Find flight deals from North Carolina to Guayaquil

Cheapest flights from North Carolina to Guayaquil
Explore the most affordable flight options available from North Carolina to Guayaquil. Find the lowest fares from popular airlines and budget airlines, with prices last updated on November 6, 2025.

This Kiwi.com deal was found by Cheapflights users on 11/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 12/58:54 amCLT - GYE
1 stop14h 49mMultiple Airlines
Tue 12/912:49 amGYE - CLT
1 stop13h 14mMultiple Airlines
Deal found 11/5$318
This Kiwi.com deal was found by Cheapflights users on 11/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 12/23:42 pmCLT - GYE
2 stops28h 43mMultiple Airlines
Mon 12/812:49 amGYE - CLT
1 stop13h 14mMultiple Airlines
Deal found 11/4$321
This KAYAK deal was found by Cheapflights users on 11/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure KAYAK is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 12/52:58 pmCLT - GYE
1 stop8h 45mSpirit Airlines
Mon 12/812:49 amGYE - CLT
1 stop13h 14mSpirit Airlines
Deal found 11/5$322
This KAYAK deal was found by Cheapflights users on 11/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure KAYAK is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 12/48:55 pmCLT - GYE
2 stops26h 48mSpirit Airlines
Sun 12/712:49 amGYE - CLT
1 stop8h 50mSpirit Airlines
Deal found 11/5$345
This Kiwi.com deal was found by Cheapflights users on 11/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 12/52:58 pmCLT - GYE
1 stop8h 45mMultiple Airlines
Mon 12/86:55 pmGYE - CLT
2 stops17h 46mMultiple Airlines
Deal found 11/5$381
This KAYAK deal was found by Cheapflights users on 11/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure KAYAK is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 12/58:55 amCLT - GYE
1 stop14h 48mSpirit Airlines
Sun 12/712:49 amGYE - CLT
2 stops19h 11mSpirit Airlines
Deal found 11/5$384
This KAYAK deal was found by Cheapflights users on 11/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure KAYAK is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 12/48:55 pmCLT - GYE
2 stops26h 48mSpirit Airlines
Mon 12/812:49 amGYE - CLT
1 stop13h 14mSpirit Airlines
Deal found 11/5$390
This Kiwi.com deal was found by Cheapflights users on 11/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 12/52:58 pmCLT - GYE
1 stop8h 45mMultiple Airlines
Tue 12/98:30 amGYE - CLT
2 stops15h 29mMultiple Airlines
Deal found 11/5$395
This CheapOair deal was found by Cheapflights users on 11/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure CheapOair is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 12/259:34 pmCLT - GYE
2 stops26h 19mSpirit Airlines
Thu 2/51:26 amGYE - CLT
1 stop16h 41mSpirit Airlines
Deal found 11/4$440
This Priceline deal was found by Cheapflights users on 11/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Priceline is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 12/259:54 amMYR - GYE
1 stop13h 59mSpirit Airlines
Tue 12/3012:49 amGYE - MYR
1 stop17h 19mSpirit Airlines
Deal found 11/4$443
This United Airlines deal was found by Cheapflights users on 11/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 12/86:30 amRDU - GYE
2 stops35h 06mUnited Airlines
Tue 1/2012:20 pmGYE - RDU
2 stops23h 54mUnited Airlines
Deal found 11/5$447
This United Airlines deal was found by Cheapflights users on 11/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 12/56:30 amRDU - GYE
2 stops35h 06mUnited Airlines
Thu 1/152:35 pmGYE - RDU
2 stops45h 39mUnited Airlines
Deal found 11/5$470

Cheap flight deals from North Carolina to Guayaquil

Keep the following information in mind while searching for North Carolina to Guayaquil flight deals. Data was last updated November 6, 2025.

Most accurate provider

eDreams
3 stars

Most trusted provider

eDreams
3 stars

Round-trip from

$307
(Travelocity)

One-way from

$122
(JetBlue)

Popular in

December

Cheapest in

November

Average price

$330
Provider with most accurate pricing for Raleigh-Durham-Guayaquil Jose Joaquin de Olmedo flight deals.
Search Deals
Provider most trusted by Cheapflights users for Raleigh-Durham-Guayaquil Jose Joaquin de Olmedo flights.
Search Deals
From North Carolina to Guayaquil Jose Joaquin de Olmedo
Search Deals
One-way flight from North Carolina to Guayaquil Jose Joaquin de Olmedo
Search Deals
High demand for flights, 7% potential price rise
Search Deals
Cheapest flight prices on average. 3% potential price decrease ($16 potential savings vs. average RT price).
Search Deals
Average for round-trip flights in November 2025
Search Deals

Cheapflights Fare Finder

 
Customize your flight search to find flights from North Carolina to Guayaquil that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated November 6, 2025.
Use the filters below to find and compare flights from North Carolina to Guayaquil that are best for you.

Fly from

North Carolina

Fly to

Guayaquil

Route

Depart

Return

Price

CharlotteGuayaquil

CLT - GYE

CLTGYE

Charlotte Douglas

Fri 12/5

8:54 am-11:43 pm

1 stop14h 49m

Guayaquil Jose Joaquin de Olmedo

Tue 12/9

12:49 am-2:03 pm

1 stop13h 14m

$318

CharlotteGuayaquil

CLT - GYE

CLTGYE

Charlotte Douglas

Thu 2/5

7:00 am-12:21 am

1 stop17h 21m

Guayaquil Jose Joaquin de Olmedo

Wed 2/18

12:59 am-6:02 pm

1 stop17h 03m

$327

CharlotteGuayaquil

CLT - GYE

CLTGYE

Charlotte Douglas

Wed 2/4

7:00 am-12:21 am

1 stop17h 21m

Guayaquil Jose Joaquin de Olmedo

Wed 2/18

12:59 am-6:02 pm

1 stop17h 03m

$332

CharlotteGuayaquil

CLT - GYE

CLTGYE

Charlotte Douglas

Thu 1/8

1:24 pm-12:21 am

1 stop10h 57m

Guayaquil Jose Joaquin de Olmedo

Wed 2/4

6:50 pm-12:22 pm

1 stop17h 32m

$375

CharlotteGuayaquil

CLT - GYE

CLTGYE

Charlotte Douglas

Thu 12/4

2:58 pm-11:43 pm

1 stop8h 45m

Guayaquil Jose Joaquin de Olmedo

Tue 12/9

12:49 am-2:03 pm

1 stop13h 14m

$401

CharlotteGuayaquil

CLT - GYE

CLTGYE

Charlotte Douglas

Thu 12/4

2:58 pm-11:43 pm

1 stop8h 45m

Guayaquil Jose Joaquin de Olmedo

Mon 12/8

12:49 am-2:03 pm

1 stop13h 14m

$401

CharlotteGuayaquil

CLT - GYE

CLTGYE

Charlotte Douglas

Sat 12/6

2:57 pm-11:43 pm

1 stop8h 46m

Guayaquil Jose Joaquin de Olmedo

Tue 12/9

12:49 am-2:03 pm

1 stop13h 14m

$401

CharlotteGuayaquil

CLT - GYE

CLTGYE

Charlotte Douglas

Sun 2/8

1:24 pm-12:21 am

1 stop10h 57m

Guayaquil Jose Joaquin de Olmedo

Sat 2/21

12:59 am-6:02 pm

1 stop17h 03m

$412

CharlotteGuayaquil

CLT - GYE

CLTGYE

Charlotte Douglas

Thu 1/8

11:12 am-12:21 am

3 stops37h 09m

Guayaquil Jose Joaquin de Olmedo

Tue 2/3

1:26 am-11:09 am

1 stop9h 43m

$419

RaleighGuayaquil

RDU - GYE

RDUGYE

Raleigh-Durham

Tue 4/14

7:08 am-1:33 pm

1 stop7h 25m

Guayaquil Jose Joaquin de Olmedo

Wed 4/22

6:40 am-9:07 pm

2 stops13h 27m

$434

Flights are sorted by cheapest round-trip flights first.

Deals found on 11/4

Showing 1-10 of 40 results
1
2
3
4

Best time to book a flight from North Carolina to Guayaquil

Have a flexible travel schedule? Discover the best time to fly to Guayaquil from North Carolina with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from North Carolina to Guayaquil

What is the cheapest month to book a flight from North Carolina to Guayaquil?

Currently, October is the cheapest month in which you can book a flight from North Carolina to Guayaquil (average of $117). Flying from North Carolina to Guayaquil in May is currently the most expensive (average of $408). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

What is the cheapest time of day to fly from NC to GYE?

Find hourly flight availability from North Carolina to Guayaquil. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated November 6, 2025.

A simple way to save on the total cost of your ticket is to fly from North Carolina to Guayaquil in the afternoon. If you’re flexible enough to do this you can expect to save up to 34% on your trip compared to booking a flight in the morning.

What is the cheapest day to fly from North Carolina to Guayaquil?

Use this chart to determine the cheapest time to fly round-trip from North Carolina to Guayaquil. Price data was last updated on December 16, 2024.

Travelers seeking maximum savings on their North Carolina to Guayaquil flight should consider departing on Wednesday afternoons when fares are most often at their lowest. Sunday at noon flights should be avoided if possible as fares are typically the most expensive at this time.

Related info for your journey

Find useful and relevant information for your journey from North Carolina to Guayaquil. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • What airport do you fly into for flights to Guayaquil from North Carolina?

    Guayaquil Jose Joaquin de Olmedo (GYE) is the airport you will fly into if you book a flight from North Carolina to Guayaquil. It is only a 2.5 mi journey from Jose Joaquin de Olmedo (GYE) to Guayaquil’s city center.

  • How long is the flight from North Carolina to Guayaquil?

    Airlines like Spirit Airlines, American Airlines, and United Airlines fly from North Carolina to Guayaquil in about 7h 25m. The time it takes to get you to your destination can typically vary by up to 27h 41m. There are 2627 mi between North Carolina and Guayaquil. When browsing for deals, the options you’ll see will be for both nonstop flights and flights with stops.

  • What are the cheapest airlines to fly from North Carolina to Guayaquil one-way?

    For one-way options, check prices for JetBlue. According to our data, you can fly for as low as $122. Users have also found prices from $155 and $218 on Spirit Airlines and American Airlines, respectively.

  • What are the most popular routes from North Carolina to Guayaquil?

    The most popular flight routes from North Carolina to Guayaquil are Charlotte Douglas - Guayaquil Jose Joaquin de Olmedo, Raleigh-Durham - Guayaquil Jose Joaquin de Olmedo and Norfolk - Guayaquil Jose Joaquin de Olmedo.

  • Can I find deals for flights from North Carolina to Guayaquil that include hotel bookings?

    Yes. In addition to deals on North Carolina to Guayaquil flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from North Carolina to Guayaquil?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from North Carolina to Guayaquil.

  • Can I find deals for business class flights from North Carolina to Guayaquil?

    Yes. Cheapflights offers flight deals from North Carolina to Guayaquil by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from North Carolina to Guayaquil?

    Currently, October is the cheapest month in which you can book a flight from North Carolina to Guayaquil (average of $117). Flying from North Carolina to Guayaquil in May is currently the most expensive (average of $408). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

Browse thousands of different options on Cheapflights for your next trip

Toggle through the tabs below to find thousands of options on Cheapflights for your next trip.

Alternative routes for North Carolina to Guayaquil

See prices for flight routes from nearby airports that may be better suited for you.
John F Kennedy Intl to Guayaquil flights
Newark to Guayaquil flights
LaGuardia to Guayaquil flights
Newark to Quito flights
John F Kennedy Intl to Quito flights
Miami to Quito flights
LaGuardia to Quito flights
Miami to Guayaquil flights
Dulles Intl to Quito flights
Fort Lauderdale to Guayaquil flights
San Francisco to Quito flights
Atlanta to Quito flights
Hobby to Quito flights
O'Hare Intl to Quito flights
Reagan-National to Quito flights
Seattle to Quito flights
Los Angeles to Quito flights
Baltimore to Quito flights
Dallas/Fort Worth to Quito flights
John F Kennedy Intl to Cuenca flights
George Bush Intcntl to Quito flights
Hobby to Guayaquil flights
Denver to Quito flights
Boston to Quito flights
Midway to Quito flights
Dulles Intl to Guayaquil flights
Orlando to Quito flights
Fort Lauderdale to Quito flights
Charlotte to Quito flights
Orlando to Guayaquil flights
Austin to Quito flights
George Bush Intcntl to Guayaquil flights
Atlanta to Guayaquil flights
Minneapolis to Guayaquil flights
O'Hare Intl to Guayaquil flights
Reagan-National to Guayaquil flights
Los Angeles to Guayaquil flights
Raleigh to Quito flights
Boston to Guayaquil flights
John F Kennedy Intl to Manta flights
Minneapolis to Quito flights
Baltimore to Guayaquil flights
Tampa to Quito flights
Charlotte to Guayaquil flights
Love Field to Quito flights
Ontario to Quito flights
Tampa to Guayaquil flights
San Francisco to Guayaquil flights
LaGuardia to Cuenca flights
Detroit to Quito flights

Top 7 airlines flying from North Carolina to Guayaquil

Discover the top 7 airlines that operate flights from North Carolina to Guayaquil. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated November 6, 2025.
AirlineCheapestAverageFlexibilityOn-time
Spirit AirlinesCheapest$116Average$599FlexibilityNo cancel feeOn-time65%
DeltaCheapest$197Average$485FlexibilityNo cancel feeOn-timeN/A
JetBlueCheapest$231Average$486FlexibilityNo cancel feeOn-time62%
Copa AirlinesCheapest$279Average$624FlexibilityNo cancel feeOn-time70%
AviancaCheapest$280Average$672FlexibilityNo cancel feeOn-time71%
LATAM AirlinesCheapest$394Average$584FlexibilityNo cancel feeOn-time81%
American AirlinesCheapest$541Average$735FlexibilityNo cancel feeOn-time71%

100% Free

Cheapflights is completely free to use, so you can start saving the moment you arrive.

Book with Flexibility

Our users can plan ahead with confidence and find flights with no change fees

Travel Smart

Millions of people come to us for their flight needs every year. We help make travel planning easy by providing useful insights and data-driven graphs that can inform your decisions.
Site
Cookie settings©2025 Cheapflights