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Guayaquil

$145+ Cheap flights from North Carolina to Guayaquil (GYE)

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 12/4. Fares are subject to change and may not be available on all flights or dates of travel.
RDU — GYE
Oct 19 — Oct 261
Sun 10/19
Sun 10/26
1 adult, Economy
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Cheap flight deals from North Carolina to Guayaquil

Keep the following information in mind while searching for North Carolina to Guayaquil flight deals. Data was last updated September 19, 2025.

Round-trip from

$350
(Cheapflightsfares)

One-way from

$145
(Orbitz)

Popular in

December

Cheapest in

November

Average price

$399
From North Carolina to Guayaquil Jose Joaquin de Olmedo
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One-way flight from North Carolina to Guayaquil Jose Joaquin de Olmedo
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High demand for flights, 4% potential price rise
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Cheapest flight prices on average. 3% potential price decrease ($15 potential savings vs. average RT price).
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Average for round-trip flights in September 2025
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Find flight deals from North Carolina to Guayaquil

Cheapest flights from North Carolina to Guayaquil
Explore the most affordable flight options available from North Carolina to Guayaquil. Find the lowest fares from popular airlines and budget airlines, with prices last updated on September 19, 2025.

This Cheapflightsfares deal was found by Cheapflights users on 9/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Cheapflightsfares is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 12/45:45 amCLT - GYE
1 stop18h 00mSpirit Airlines
Sun 12/712:59 amGYE - CLT
1 stop8h 28mSpirit Airlines
Deal found 9/17$350
This KAYAK deal was found by Cheapflights users on 9/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure KAYAK is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 12/55:45 amCLT - GYE
1 stop18h 00mSpirit Airlines
Sun 12/712:59 amGYE - CLT
1 stop8h 28mSpirit Airlines
Deal found 9/16$354
This KAYAK deal was found by Cheapflights users on 9/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure KAYAK is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 12/49:49 amCLT - GYE
1 stop13h 56mSpirit Airlines
Mon 12/812:59 amGYE - CLT
1 stop8h 28mSpirit Airlines
Deal found 9/16$361
This KAYAK deal was found by Cheapflights users on 9/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure KAYAK is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 12/45:45 amCLT - GYE
1 stop18h 00mSpirit Airlines
Fri 12/512:59 amGYE - CLT
1 stop8h 28mSpirit Airlines
Deal found 9/16$363
This Mytrip deal was found by Cheapflights users on 9/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Mytrip is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 10/15:45 amCLT - GYE
2 stops18h 35mMultiple Airlines
Wed 10/156:25 pmGYE - CLT
2 stops28h 03mMultiple Airlines
Deal found 9/18$382
This Kiwi.com deal was found by Cheapflights users on 9/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 12/510:32 amCLT - GYE
1 stop18h 48mMultiple Airlines
Mon 12/84:40 amGYE - CLT
2 stops20h 19mMultiple Airlines
Deal found 9/16$391
This United Airlines deal was found by Cheapflights users on 9/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/306:07 amRDU - GYE
2 stops30h 09mUnited Airlines
Tue 11/188:30 amGYE - RDU
2 stops37h 24mUnited Airlines
Deal found 9/18$393
This Kiwi.com deal was found by Cheapflights users on 9/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 12/49:49 amCLT - GYE
1 stop13h 56mMultiple Airlines
Tue 12/96:55 pmGYE - CLT
2 stops30h 04mMultiple Airlines
Deal found 9/16$408
This CheapOair deal was found by Cheapflights users on 9/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure CheapOair is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 11/1912:35 pmRDU - GYE
1 stop25h 31mJetBlue
Wed 12/34:31 pmGYE - RDU
1 stop22h 04mJetBlue
Deal found 9/17$424
This CheapOair deal was found by Cheapflights users on 9/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure CheapOair is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 11/1512:35 pmRDU - GYE
1 stop25h 45mJetBlue
Fri 12/54:31 pmGYE - RDU
1 stop22h 04mJetBlue
Deal found 9/17$432
This Copa Airlines deal was found by Cheapflights users on 9/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Copa Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 11/203:14 pmRDU - GYE
1 stop8h 27mCopa Airlines
Tue 12/24:32 amGYE - RDU
1 stop8h 53mCopa Airlines
Deal found 9/17$453
This United Airlines deal was found by Cheapflights users on 9/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 11/196:07 amRDU - GYE
2 stops31h 27mUnited Airlines
Wed 12/38:30 amGYE - RDU
2 stops37h 45mUnited Airlines
Deal found 9/17$456

Cheapflights Fare Finder

 
Customize your flight search to find flights from North Carolina to Guayaquil that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated September 19, 2025.
Use the filters below to find and compare flights from North Carolina to Guayaquil that are best for you.

Fly from

North Carolina

Fly to

Guayaquil

Route

Depart

Return

Price

CharlotteGuayaquil

CLT - GYE

CLTGYE

Charlotte Douglas

Thu 12/4

9:49 am-11:45 pm

1 stop13h 56m

Guayaquil Jose Joaquin de Olmedo

Mon 12/8

12:59 am-9:27 am

1 stop8h 28m

$361

RaleighGuayaquil

RDU - GYE

RDUGYE

Raleigh-Durham

Sat 11/15

6:04 am-1:34 pm

2 stops31h 30m

Guayaquil Jose Joaquin de Olmedo

Fri 12/5

8:30 am-10:15 pm

2 stops13h 45m

$393

CharlotteGuayaquil

CLT - GYE

CLTGYE

Charlotte Douglas

Fri 10/3

10:17 am-11:20 pm

2 stops14h 03m

Guayaquil Jose Joaquin de Olmedo

Fri 10/10

3:35 am-8:59 pm

2 stops16h 24m

$426

CharlotteGuayaquil

CLT - GYE

CLTGYE

Charlotte Douglas

Wed 10/8

5:45 am-11:20 pm

2 stops18h 35m

Guayaquil Jose Joaquin de Olmedo

Mon 10/20

3:35 am-11:28 pm

2 stops18h 53m

$426

CharlotteGuayaquil

CLT - GYE

CLTGYE

Charlotte Douglas

Thu 12/4

12:00 pm-11:45 pm

2 stops11h 45m

Guayaquil Jose Joaquin de Olmedo

Fri 12/5

12:59 am-8:37 am

2 stops31h 38m

$435

CharlotteGuayaquil

CLT - GYE

CLTGYE

Charlotte Douglas

Wed 2/4

5:45 am-11:45 pm

1 stop18h 00m

Guayaquil Jose Joaquin de Olmedo

Wed 2/18

12:59 am-1:21 pm

2 stops12h 22m

$445

CharlotteGuayaquil

CLT - GYE

CLTGYE

Charlotte Douglas

Sat 11/1

1:49 pm-5:20 am

1 stop16h 31m

Guayaquil Jose Joaquin de Olmedo

Sat 11/8

6:50 pm-4:01 pm

1 stop21h 11m

$455

CharlotteGuayaquil

CLT - GYE

CLTGYE

Charlotte Douglas

Sat 10/18

5:45 am-10:40 pm

2 stops17h 55m

Guayaquil Jose Joaquin de Olmedo

Sat 10/25

4:15 am-11:28 pm

2 stops18h 13m

$460

RaleighGuayaquil

RDU - GYE

RDUGYE

Raleigh-Durham

Tue 2/3

2:00 pm-7:20 am

1 stop17h 20m

Guayaquil Jose Joaquin de Olmedo

Sun 2/15

4:30 pm-9:54 am

1 stop17h 24m

$462

RaleighGuayaquil

RDU - GYE

RDUGYE

Raleigh-Durham

Tue 2/3

2:00 pm-7:20 am

1 stop17h 20m

Guayaquil Jose Joaquin de Olmedo

Sat 2/14

4:30 pm-9:54 am

1 stop17h 24m

$462

Flights are sorted by cheapest round-trip flights first.

Deals found on 9/18

Showing 1-10 of 44 results
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Best time to book a flight from North Carolina to Guayaquil

Have a flexible travel schedule? Discover the best time to fly to Guayaquil from North Carolina with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from North Carolina to Guayaquil

What is the cheapest month to book a flight from North Carolina to Guayaquil?

Currently, April is the cheapest month in which you can book a flight from North Carolina to Guayaquil (average of $440). Flying from North Carolina to Guayaquil in December is currently the most expensive (average of $722). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

What is the cheapest time of day to fly from NC to GYE?

Find hourly flight availability from North Carolina to Guayaquil. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated September 19, 2025.

Regardless of the time of day you decide to fly, the ticket price will remain around the same. Book flights from North Carolina to Guayaquil as you normally would.

How much does it cost to fly round-trip from North Carolina to Guayaquil?

Related info for your journey

Find useful and relevant information for your journey from North Carolina to Guayaquil. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • What airport do you fly into for flights to Guayaquil from North Carolina?

    Guayaquil Jose Joaquin de Olmedo (GYE) is the airport you will fly into if you book a flight from North Carolina to Guayaquil. It is only a 2.5 mi journey from Jose Joaquin de Olmedo (GYE) to Guayaquil’s city center.

  • How long is the flight from North Carolina to Guayaquil?

    Airlines like Spirit Airlines, United Airlines, and Delta fly from North Carolina to Guayaquil in about 13h 56m. The time it takes to get you to your destination can typically vary by up to 17h 34m. There are 2582 mi between North Carolina and Guayaquil. When browsing for deals, the options you’ll see will be for both nonstop flights and flights with stops.

  • What are the most popular routes from North Carolina to Guayaquil?

    The most popular flight routes from North Carolina to Guayaquil are Charlotte Douglas - Guayaquil Jose Joaquin de Olmedo, Raleigh-Durham - Guayaquil Jose Joaquin de Olmedo and Norfolk - Guayaquil Jose Joaquin de Olmedo.

  • Can I find deals for flights from North Carolina to Guayaquil that include hotel bookings?

    Yes. In addition to deals on North Carolina to Guayaquil flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from North Carolina to Guayaquil?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from North Carolina to Guayaquil.

  • Can I find deals for business class flights from North Carolina to Guayaquil?

    Yes. Cheapflights offers flight deals from North Carolina to Guayaquil by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from North Carolina to Guayaquil?

    Currently, April is the cheapest month in which you can book a flight from North Carolina to Guayaquil (average of $440). Flying from North Carolina to Guayaquil in December is currently the most expensive (average of $722). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

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Alternative routes for North Carolina to Guayaquil

See prices for flight routes from nearby airports that may be better suited for you.
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Top 6 airlines flying from North Carolina to Guayaquil

Discover the top 6 airlines that operate flights from North Carolina to Guayaquil. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated September 19, 2025.
AirlineCheapestAverageFlexibilityOn-time
Spirit AirlinesCheapest$155Average$482FlexibilityNo cancel feeOn-time65%
JetBlueCheapest$231Average$487FlexibilityNo cancel feeOn-time62%
Copa AirlinesCheapest$279Average$618FlexibilityNo cancel feeOn-time70%
AviancaCheapest$280Average$672FlexibilityNo cancel feeOn-time71%
LATAM AirlinesCheapest$394Average$584FlexibilityNo cancel feeOn-time81%
American AirlinesCheapest$517Average$689FlexibilityNo cancel feeOn-time71%

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