HomeSearch by dateVacation packagesHotelsFlight dealsCar rentalTravel tips & news
Guayaquil

$301+ Cheap flights from Columbus to Guayaquil (GYE)

This is the cheapest round-trip flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 1/21. Fares are subject to change and may not be available on all flights or dates of travel.
CMH — GYE
Jan 27 — Feb 31
Tue 1/27
Tue 2/3
1 adult, Economy
We work with more than 300 partners to bring you better travel deals

Find cheap flights from Columbus to Guayaquil with Cheapflights

1. Tell us where you want to go

Enter your travel information like dates, passengers, trip type (one-way or round trip), and preferred cabin class then click “Find deals”

2. Select your favorite providers

We find the providers serving your travel needs. Choose up to four travel providers to compare side-by-side for flights, hotels, or car rentals.

3. Compare prices and book

Review each provider’s pricing and select the best option for you! Book through your favorite provider’s website for a seamless experience.

Cheap flight deals from Columbus to Guayaquil

Cheapest flights from Columbus to Guayaquil
Explore the most affordable flight options available from Columbus to Guayaquil. Find the lowest fares from popular airlines and budget airlines, with prices last updated on December 28, 2025.

This FlightHub deal was found by Cheapflights users on 12/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure FlightHub is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 12/3011:14 amCMH - GYE
1 stop12h 39mSpirit Airlines
Wed 1/71:26 amGYE - CMH
2 stops21h 53mSpirit Airlines
Deal found 12/26$733
This FlightHub deal was found by Cheapflights users on 12/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure FlightHub is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 12/3111:14 amCMH - GYE
1 stop12h 39mSpirit Airlines
Thu 1/81:26 amGYE - CMH
2 stops21h 53mSpirit Airlines
Deal found 12/26$775
This American Airlines deal was found by Cheapflights users on 12/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 12/318:39 amCMH - GYE
2 stops15h 11mAmerican Airlines
Fri 1/97:15 amGYE - CMH
2 stops16h 07mAmerican Airlines
Deal found 12/26$1,144
This United Airlines deal was found by Cheapflights users on 12/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 12/305:40 amCMH - GYE
2 stops18h 01mUnited Airlines
Thu 1/812:20 pmGYE - CMH
2 stops25h 02mUnited Airlines
Deal found 12/26$1,181
This American Airlines deal was found by Cheapflights users on 12/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 12/306:01 amCMH - GYE
1 stop17h 49mAmerican Airlines
Thu 1/87:15 amGYE - CMH
1 stop27h 42mAmerican Airlines
Deal found 12/26$1,235

Find flight deals from Columbus to Guayaquil

Discover tips and strategies to find the most affordable flight options for your journey from Columbus (C01) to Guayaquil (GYE). Learn about various techniques such as flexible date searches, comparing prices across and setting up price alerts. Use these methods to find the cheapest flights available for your travel needs. Data last updated December 28, 2025.

Round-trip from

$301
(Orbitz)

Popular in

July

Cheapest in

March

Average price

$1,037
From Columbus to Guayaquil Jose Joaquin de Olmedo
Search Deals
High demand for flights, 3% potential price rise
Search Deals
Cheapest flight prices on average. 2% potential price decrease ($24 potential savings vs. average RT price).
Search Deals
Average for round-trip flights in December 2025
Search Deals

Cheapflights Fare Finder

 
Customize your flight search to find flights from Columbus to Guayaquil that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated December 28, 2025.
Use the filters below to find and compare flights from Columbus to Guayaquil that are best for you.

Fly from

Columbus

Fly to

Guayaquil

Route

Depart

Return

Price

ColumbusGuayaquil

CMH - GYE

CMHGYE

Columbus

Wed 1/21

5:45 am-12:21 am

1 stop18h 36m

Guayaquil Jose Joaquin de Olmedo

Fri 2/6

1:26 am-11:19 pm

2 stops21h 53m

$301

ColumbusGuayaquil

CMH - GYE

CMHGYE

Columbus

Wed 1/21

5:45 am-12:21 am

1 stop18h 36m

Guayaquil Jose Joaquin de Olmedo

Sat 2/7

1:26 am-10:47 am

2 stops33h 21m

$314

ColumbusGuayaquil

CMH - GYE

CMHGYE

Columbus

Wed 1/21

6:06 am-12:21 am

2 stops18h 15m

Guayaquil Jose Joaquin de Olmedo

Sat 2/7

1:26 am-11:19 pm

3 stops21h 53m

$440

ColumbusGuayaquil

CMH - GYE

CMHGYE

Columbus

Mon 2/2

6:30 am-8:46 pm

2 stops14h 16m

Guayaquil Jose Joaquin de Olmedo

Wed 2/4

12:20 pm-10:29 pm

2 stops34h 09m

$706

ColumbusGuayaquil

CMH - GYE

CMHGYE

Columbus

Sun 1/25

6:30 am-8:46 pm

2 stops14h 16m

Guayaquil Jose Joaquin de Olmedo

Thu 1/29

2:35 pm-10:29 pm

2 stops31h 54m

$716

ColumbusGuayaquil

CMH - GYE

CMHGYE

Columbus

Mon 2/2

12:57 pm-7:20 am

1 stop18h 23m

Guayaquil Jose Joaquin de Olmedo

Wed 2/4

4:30 pm-12:14 pm

1 stop19h 44m

$724

ColumbusGuayaquil

CMH - GYE

CMHGYE

Columbus

Sun 1/25

12:57 pm-7:20 am

1 stop18h 23m

Guayaquil Jose Joaquin de Olmedo

Thu 1/29

4:30 pm-12:10 pm

1 stop19h 40m

$724

Flights are sorted by cheapest round-trip flights first.

Deals found on 12/26

Best time to book a flight from Columbus to Guayaquil

Have a flexible travel schedule? Discover the best time to fly to Guayaquil from Columbus with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Columbus to Guayaquil

What is the cheapest month to book a flight from Columbus to Guayaquil?

Currently, March is the cheapest month in which you can book a flight from Columbus to Guayaquil (average of $503). Flying from Columbus to Guayaquil in October is currently the most expensive (average of $792). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

Reviews of airlines servicing Guayaquil

Get insights into the airlines that provide service to Guayaquil. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Guayaquil. Reviews last updated December 28, 2025.
Read through reviews of airlines operating flights from Columbus to Guayaquil, such as American Airlines. Reviews also offer insight into each airline's entertainment options, comfort, food, crew/service, and boarding process.
American Airlines
7.2
Good
11,072 reviews

Entertainment

6.9

Food

6.5

Comfort

7.2

Crew

8.0

Boarding

7.5

Overall

7.2

Reviews

1 / 20
10.0
Excellent

Jeremy,Dec 2025

OKC - CLT

Was an okay flight. Had extra seat empty beside me so was able to stretch a bit
American Airlines
7.2
Good
11,072 reviews
American Airlines
7.2
Good
11,072 reviews

Entertainment

6.9

Food

6.5

Comfort

7.2

Crew

8.0

Boarding

7.5

Overall

7.2

Reviews

1 / 20
10.0
Excellent

Jeremy,Dec 2025

OKC - CLT

Was an okay flight. Had extra seat empty beside me so was able to stretch a bit

Related info for your journey

Find useful and relevant information for your journey from Columbus to Guayaquil. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • What airport do you fly into for flights to Guayaquil from Columbus?

    Guayaquil Jose Joaquin de Olmedo (GYE), located 2.5 mi from the city center, is the airport you fly into when you book flights from Columbus to Guayaquil. 1 airline have flights to Jose Joaquin de Olmedo from Columbus on a regular basis. Booking flights from Columbus to Guayaquil Jose Joaquin de Olmedo should not be difficult; the airport handles an average of 0 inbound flights from Columbus per day.

  • How long is the flight from Columbus to Guayaquil?

    Departing from Columbus to Guayaquil will take you 18h 36m. Columbus and Guayaquil are separated by a distance of 2917 mi.

  • What is the cheapest airline to fly from Columbus to Guayaquil round-trip?

    Currently priced at $682, American Airlines will fly you from Columbus to Guayaquil and back. In addition to American Airlines, many other airlines offer competitively priced options for your trip. You may be able to fly from Columbus to Guayaquil for 17% less than the average price by searching for this airline.

  • Can I find deals for flights from Columbus to Guayaquil that include hotel bookings?

    Yes. In addition to deals on Columbus to Guayaquil flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Columbus to Guayaquil?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Columbus to Guayaquil.

  • Can I find deals for business class flights from Columbus to Guayaquil?

    Yes. Cheapflights offers flight deals from Columbus to Guayaquil by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Columbus to Guayaquil?

    Currently, March is the cheapest month in which you can book a flight from Columbus to Guayaquil (average of $503). Flying from Columbus to Guayaquil in October is currently the most expensive (average of $792). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

Browse thousands of different options on Cheapflights for your next trip

Toggle through the tabs below to find thousands of options on Cheapflights for your next trip.

Top airline flying from Columbus to Guayaquil

Discover the top airline that operate flights from Columbus to Guayaquil. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated December 28, 2025.
AirlineCheapestAverageFlexibilityOn-time
American AirlinesCheapest$682Average$929FlexibilityNo cancel feeOn-time71%

100% Free

Cheapflights is completely free to use, so you can start saving the moment you arrive.

Book with Flexibility

Our users can plan ahead with confidence and find flights with no change fees

Travel Smart

Millions of people come to us for their flight needs every year. We help make travel planning easy by providing useful insights and data-driven graphs that can inform your decisions.