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Guayaquil

$344+ Cheap flights from Columbus to Guayaquil (GYE)

This is the cheapest round-trip flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 5/12. Fares are subject to change and may not be available on all flights or dates of travel.
CMH — GYE
Mar 14 — Mar 211
Sat 3/14
Sat 3/21
1 adult, Economy
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Cheap flight deals from Columbus to Guayaquil

Cheapest flights from Columbus to Guayaquil
Explore the most affordable flight options available from Columbus to Guayaquil. Find the lowest fares from popular airlines and budget airlines, with prices last updated on February 12, 2026.

This FlightHub deal was found by Cheapflights users on 2/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure FlightHub is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 5/126:00 am
CMH
-
GYE
1 stop18h 04m
Spirit Airlines
Fri 5/2211:59 pm
GYE
-
CMH
1 stop13h 46m
Spirit Airlines
Deal found 2/11$344
This Kiwi.com deal was found by Cheapflights users on 2/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 3/1710:40 am
CMH
-
GYE
1 stop13h 24m
Multiple Airlines
Tue 4/1411:59 pm
GYE
-
CMH
2 stops37h 42m
Multiple Airlines
Deal found 2/10$347
This Kiwi.com deal was found by Cheapflights users on 2/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 5/166:25 am
CMH
-
GYE
1 stop17h 36m
Spirit Airlines
Tue 5/2611:59 pm
GYE
-
CMH
1 stop21h 14m
Spirit Airlines
Deal found 2/9$351
This Kiwi.com deal was found by Cheapflights users on 2/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 3/1710:40 am
CMH
-
GYE
1 stop13h 24m
Multiple Airlines
Sat 4/1811:59 pm
GYE
-
CMH
2 stops37h 42m
Multiple Airlines
Deal found 2/10$356
This Kiwi.com deal was found by Cheapflights users on 2/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 3/1710:40 am
CMH
-
GYE
1 stop13h 24m
Multiple Airlines
Wed 4/1511:59 pm
GYE
-
CMH
2 stops13h 42m
Multiple Airlines
Deal found 2/10$357
This Kiwi.com deal was found by Cheapflights users on 2/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 3/1710:40 am
CMH
-
GYE
1 stop13h 24m
Multiple Airlines
Fri 4/1711:59 pm
GYE
-
CMH
2 stops37h 42m
Multiple Airlines
Deal found 2/10$365
This Kiwi.com deal was found by Cheapflights users on 2/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 3/1710:40 am
CMH
-
GYE
1 stop13h 24m
Multiple Airlines
Thu 4/1611:59 pm
GYE
-
CMH
2 stops13h 42m
Multiple Airlines
Deal found 2/10$374
This Kiwi.com deal was found by Cheapflights users on 2/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 5/176:25 am
CMH
-
GYE
1 stop17h 36m
Spirit Airlines
Tue 5/2611:59 pm
GYE
-
CMH
1 stop21h 14m
Spirit Airlines
Deal found 2/9$378
This Kiwi.com deal was found by Cheapflights users on 2/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 3/1910:40 am
CMH
-
GYE
1 stop13h 24m
Multiple Airlines
Tue 4/1411:59 pm
GYE
-
CMH
2 stops37h 42m
Multiple Airlines
Deal found 2/10$379
This Kiwi.com deal was found by Cheapflights users on 2/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 3/1910:40 am
CMH
-
GYE
1 stop13h 24m
Multiple Airlines
Sat 4/1811:59 pm
GYE
-
CMH
2 stops37h 42m
Multiple Airlines
Deal found 2/10$388
This Kiwi.com deal was found by Cheapflights users on 2/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 3/165:45 am
CMH
-
GYE
1 stop18h 19m
Multiple Airlines
Wed 4/1511:59 pm
GYE
-
CMH
2 stops13h 42m
Multiple Airlines
Deal found 2/10$390

Find flight deals from Columbus to Guayaquil

Discover tips and strategies to find the most affordable flight options for your journey from Columbus (C01) to Guayaquil (GYE). Learn about various techniques such as flexible date searches, comparing prices across and setting up price alerts. Use these methods to find the cheapest flights available for your travel needs. Data last updated February 12, 2026.

Round-trip from

$344
(FlightHub)

Popular in

July

Cheapest in

March

Average price

$771
From Columbus to Guayaquil Jose Joaquin de Olmedo
Search Deals
Highest demand for flights based on searches. 0% potential increase in price ($1 potential increase over avg. RT price).
Search Deals
Cheapest flight prices on average. 3% potential price decrease ($27 potential savings vs. average RT price).
Search Deals
Average for round-trip flights in February 2026
Search Deals

Cheapflights Fare Finder

 
Customize your flight search to find flights from Columbus to Guayaquil that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated February 12, 2026.
Use the filters below to find and compare flights from Columbus to Guayaquil that are best for you.

Fly from

Columbus

Fly to

Guayaquil

Route

Depart

Return

Price

ColumbusGuayaquil

CMH - GYE

CMHGYE

Columbus

Tue 5/12

6:00 am-11:04 pm

1 stop18h 04m

Guayaquil Jose Joaquin de Olmedo

Fri 5/22

11:59 pm-2:45 pm

1 stop13h 46m

$344

ColumbusGuayaquil

CMH - GYE

CMHGYE

Columbus

Wed 3/18

10:40 am-11:04 pm

1 stop13h 24m

Guayaquil Jose Joaquin de Olmedo

Sat 4/18

11:59 pm-2:41 pm

2 stops37h 42m

$356

ColumbusGuayaquil

CMH - GYE

CMHGYE

Columbus

Tue 3/17

10:40 am-11:04 pm

1 stop13h 24m

Guayaquil Jose Joaquin de Olmedo

Tue 4/14

11:59 pm-10:13 pm

1 stop21h 14m

$357

ColumbusGuayaquil

CMH - GYE

CMHGYE

Columbus

Wed 3/18

10:40 am-11:04 pm

1 stop13h 24m

Guayaquil Jose Joaquin de Olmedo

Fri 4/17

11:59 pm-2:41 pm

2 stops37h 42m

$365

ColumbusGuayaquil

CMH - GYE

CMHGYE

Columbus

Mon 3/16

5:45 am-1:05 am

2 stops20h 20m

Guayaquil Jose Joaquin de Olmedo

Wed 4/15

4:05 am-10:13 pm

2 stops17h 08m

$541

ColumbusGuayaquil

CMH - GYE

CMHGYE

Columbus

Thu 3/19

10:40 am-11:04 pm

1 stop13h 24m

Guayaquil Jose Joaquin de Olmedo

Sun 4/12

4:29 am-10:49 pm

2 stops17h 20m

$564

ColumbusGuayaquil

CMH - GYE

CMHGYE

Columbus

Fri 3/13

5:45 am-11:04 pm

1 stop18h 19m

Guayaquil Jose Joaquin de Olmedo

Tue 4/14

11:59 pm-10:13 pm

1 stop21h 14m

$569

ColumbusGuayaquil

CMH - GYE

CMHGYE

Columbus

Fri 5/15

6:25 am-11:01 pm

1 stop17h 36m

Guayaquil Jose Joaquin de Olmedo

Mon 5/25

8:28 am-10:13 pm

2 stops12h 45m

$627

ColumbusGuayaquil

CMH - GYE

CMHGYE

Columbus

Sun 5/17

6:25 am-11:01 pm

1 stop17h 36m

Guayaquil Jose Joaquin de Olmedo

Mon 5/25

11:59 pm-10:13 pm

1 stop21h 14m

$647

ColumbusGuayaquil

CMH - GYE

CMHGYE

Columbus

Tue 6/9

6:00 am-10:37 pm

2 stops17h 37m

Guayaquil Jose Joaquin de Olmedo

Thu 7/30

2:33 pm-9:02 am

2 stops17h 29m

$658

Flights are sorted by cheapest round-trip flights first.

Deals found on 2/11

Best time to book a flight from Columbus to Guayaquil

Have a flexible travel schedule? Discover the best time to fly to Guayaquil from Columbus with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Columbus to Guayaquil

What is the cheapest month to book a flight from Columbus to Guayaquil?

Currently, March is the cheapest month in which you can book a flight from Columbus to Guayaquil (average of $503). Flying from Columbus to Guayaquil in October is currently the most expensive (average of $792). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

Reviews of airlines servicing Guayaquil

Get insights into the airlines that provide service to Guayaquil. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Guayaquil. Reviews last updated February 12, 2026.
Read through reviews of airlines operating flights from Columbus to Guayaquil, such as American Airlines. Reviews also offer insight into each airline's entertainment options, comfort, food, crew/service, and boarding process.
American Airlines
7.2
Good
11,267 reviews

Comfort

7.2

Crew

8.0

Overall

7.2

Food

6.4

Entertainment

6.9

Boarding

7.5

Reviews

1 / 20
2.0
Mediocre

Susie,Jan 2026

CLT - TPA

This flight was delayed 3 or 4 times. We had boarded the plane, sat on plane for a good 30 minutes, then we had to board the aircraft, walk to a different gate, wait and then board another aircraft. We arrived in Tampa 4 hours later than the original booking. I feel there should have been some sort of compensation especially for the advantage members.
American Airlines
7.2
Good
11,267 reviews
American Airlines
7.2
Good
11,267 reviews

Comfort

7.2

Crew

8.0

Overall

7.2

Food

6.4

Entertainment

6.9

Boarding

7.5

Reviews

1 / 20
2.0
Mediocre

Susie,Jan 2026

CLT - TPA

This flight was delayed 3 or 4 times. We had boarded the plane, sat on plane for a good 30 minutes, then we had to board the aircraft, walk to a different gate, wait and then board another aircraft. We arrived in Tampa 4 hours later than the original booking. I feel there should have been some sort of compensation especially for the advantage members.

Related info for your journey

Find useful and relevant information for your journey from Columbus to Guayaquil. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • What airport do you fly into for flights to Guayaquil from Columbus?

    Guayaquil Jose Joaquin de Olmedo (GYE), located 2.5 mi from the city center, is the airport you fly into when you book flights from Columbus to Guayaquil. 1 airline have flights to Jose Joaquin de Olmedo from Columbus on a regular basis. Booking flights from Columbus to Guayaquil Jose Joaquin de Olmedo should not be difficult; the airport handles an average of 0 inbound flights from Columbus per day.

  • How long is the flight from Columbus to Guayaquil?

    Departing from Columbus to Guayaquil will take you 18h 04m. Columbus and Guayaquil are separated by a distance of 2917 mi.

  • What is the cheapest airline to fly from Columbus to Guayaquil round-trip?

    Currently priced at $655, American Airlines will fly you from Columbus to Guayaquil and back. In addition to American Airlines, many other airlines offer competitively priced options for your trip. You may be able to fly from Columbus to Guayaquil for 17% less than the average price by searching for this airline.

  • Can I find deals for flights from Columbus to Guayaquil that include hotel bookings?

    Yes. In addition to deals on Columbus to Guayaquil flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Columbus to Guayaquil?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Columbus to Guayaquil.

  • Can I find deals for business class flights from Columbus to Guayaquil?

    Yes. Cheapflights offers flight deals from Columbus to Guayaquil by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Columbus to Guayaquil?

    Currently, March is the cheapest month in which you can book a flight from Columbus to Guayaquil (average of $503). Flying from Columbus to Guayaquil in October is currently the most expensive (average of $792). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

Browse thousands of different options on Cheapflights for your next trip

Toggle through the tabs below to find thousands of options on Cheapflights for your next trip.

Top airline flying from Columbus to Guayaquil

Discover the top airline that operate flights from Columbus to Guayaquil. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated February 12, 2026.
AirlineCheapestAverageFlexibilityOn-time
American AirlinesCheapest$655Average$901FlexibilityNo cancel feeOn-time71%

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