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Guayaquil

$274+ Cheap flights from Cali (CLO) to Guayaquil (GYE)

This is the cheapest round-trip flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 12/27. Fares are subject to change and may not be available on all flights or dates of travel.
CLO — GYE
Jan 13 — Jan 201
Tue 1/13
Tue 1/20
1 adult, Economy
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Cheapflights Tip: The best prices from Cali Alfonso B. Aragon Intl to Guayaquil Jose Joaquin de Olmedo are usually found in June or May, booked 52 days in advance, depart on a Wednesday or Thursday and return on a Saturday

Cheap flight deals from Cali to Guayaquil

Cheapest flights from Cali to Guayaquil
Explore the most affordable flight options available from Cali to Guayaquil. Find the lowest fares from popular airlines and budget airlines, with prices last updated on December 14, 2025.

This Avianca deal was found by Cheapflights users on 12/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Avianca is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 12/278:20 amCLO - GYE
1 stop6h 10mAvianca
Sat 12/273:30 amGYE - CLO
1 stop6h 00mAvianca
Deal found 12/14$274
This Copa Airlines deal was found by Cheapflights users on 12/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Copa Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 12/135:01 amCLO - GYE
1 stop12h 35mCopa Airlines
Sat 12/206:34 pmGYE - CLO
1 stop5h 03mCopa Airlines
Deal found 12/12$356
This Mytrip deal was found by Cheapflights users on 12/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Mytrip is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 12/277:55 amCLO - GYE
1 stop6h 35mMultiple Airlines
Sun 1/182:25 pmGYE - CLO
2 stops9h 40mMultiple Airlines
Deal found 12/14$387
This Kiwi.com deal was found by Cheapflights users on 12/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 12/278:20 amCLO - GYE
1 stop6h 10mMultiple Airlines
Sun 12/286:34 pmGYE - CLO
2 stops12h 02mMultiple Airlines
Deal found 12/14$402
This LATAM Airlines deal was found by Cheapflights users on 12/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure LATAM Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 12/276:22 amCLO - GYE
2 stops9h 36mLATAM Airlines
Sun 1/184:10 pmGYE - CLO
2 stops7h 55mLATAM Airlines
Deal found 12/14$520
This Expedia deal was found by Cheapflights users on 12/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Expedia is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 12/2712:35 pmCLO - GYE
2 stops20h 55mLATAM Airlines
Sun 12/284:10 pmGYE - CLO
2 stops7h 45mLATAM Airlines
Deal found 12/14$577

Find flight deals from Cali to Guayaquil

Discover tips and strategies to find the most affordable flight options for your journey from Cali (CLO) to Guayaquil (GYE). Learn about various techniques such as flexible date searches, comparing prices across and setting up price alerts. Use these methods to find the cheapest flights available for your travel needs. Data last updated December 14, 2025.

Most accurate provider

eDreams
3 stars

Most trusted provider

eDreams
3 stars

Round-trip from

$274
(Avianca)

Popular in

December

Cheapest in

June

Average price

$379
Provider with most accurate pricing for Cali Alfonso B. Aragon Intl-Guayaquil Jose Joaquin de Olmedo flight deals.
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Provider most trusted by Cheapflights users for Cali Alfonso B. Aragon Intl-Guayaquil Jose Joaquin de Olmedo flights.
Search Deals
From Cali Alfonso B. Aragon Intl to Guayaquil Jose Joaquin de Olmedo
Search Deals
Highest demand for flights based on searches. 6% potential increase in price ($21 potential increase over avg. RT price).
Search Deals
Cheapest flight prices on average. 1% potential price decrease ($7 potential savings vs. average RT price).
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Average for round-trip flights in December 2025
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Cheapflights Fare Finder

 
Customize your flight search to find flights from Cali to Guayaquil that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated December 14, 2025.
Use the filters below to find and compare flights from Cali to Guayaquil that are best for you.

Fly from

Cali

Fly to

Guayaquil

Route

Depart

Return

Price

CaliGuayaquil

CLO - GYE

CLOGYE

Cali Alfonso B. Aragon Intl

Sat 12/27

8:20 am-2:30 pm

1 stop6h 10m

Guayaquil Jose Joaquin de Olmedo

Sat 12/27

3:30 am-9:30 am

1 stop6h 00m

$274

CaliGuayaquil

CLO - GYE

CLOGYE

Cali Alfonso B. Aragon Intl

Sat 12/27

8:20 am-2:30 pm

1 stop6h 10m

Guayaquil Jose Joaquin de Olmedo

Sun 1/18

10:25 am-2:45 pm

1 stop4h 20m

$274

CaliGuayaquil

CLO - GYE

CLOGYE

Cali Alfonso B. Aragon Intl

Thu 4/23

4:24 am-8:35 am

1 stop4h 11m

Guayaquil Jose Joaquin de Olmedo

Mon 4/27

9:45 am-2:20 pm

1 stop4h 35m

$274

CaliGuayaquil

CLO - GYE

CLOGYE

Cali Alfonso B. Aragon Intl

Wed 1/7

8:40 am-2:25 pm

1 stop5h 45m

Guayaquil Jose Joaquin de Olmedo

Wed 1/14

3:35 pm-7:55 pm

1 stop4h 20m

$275

CaliGuayaquil

CLO - GYE

CLOGYE

Cali Alfonso B. Aragon Intl

Thu 1/8

10:15 am-2:30 pm

1 stop4h 15m

Guayaquil Jose Joaquin de Olmedo

Wed 1/14

4:40 am-9:30 am

1 stop4h 50m

$275

CaliGuayaquil

CLO - GYE

CLOGYE

Cali Alfonso B. Aragon Intl

Sun 1/11

10:15 am-2:30 pm

1 stop4h 15m

Guayaquil Jose Joaquin de Olmedo

Sun 1/18

9:05 am-1:20 pm

1 stop4h 15m

$322

CaliGuayaquil

CLO - GYE

CLOGYE

Cali Alfonso B. Aragon Intl

Sun 1/25

12:03 pm-5:35 pm

1 stop5h 32m

Guayaquil Jose Joaquin de Olmedo

Thu 2/12

8:34 am-2:10 pm

1 stop5h 36m

$380

CaliGuayaquil

CLO - GYE

CLOGYE

Cali Alfonso B. Aragon Intl

Sun 1/25

12:03 pm-5:35 pm

1 stop5h 32m

Guayaquil Jose Joaquin de Olmedo

Sat 1/31

8:34 am-2:10 pm

1 stop5h 36m

$401

Flights are sorted by cheapest round-trip flights first.

Deals found on 12/14

Compare providers for flights from Cali to Guayaquil

Provider information is updated monthly. Please note that these providers often have deals for this flight, but the availability may vary on a day-by-day basis on Cheapflights.
Use the table below to compare price accuracy, trust ratings, and cancellation policies for each provider offering flight deals from Cali to Guayaquil in December.
ProviderPrice AccuracyTrust Score*
eDreamsPrice Accuracy3 starsTrust Score*3 stars
FlightHubPrice Accuracy3 starsTrust Score*1 star

*The Trust Score is based on feedback from users after their booking experience. It measures overall satisfaction, helping us identify issues like hidden fees, problems during the ticketing process, and the quality of customer service. This score is our best indicator of the provider's quality and reliability.

  • Most accurate provider: When it comes to deals on Cali-Guayaquil flights, users find the pricing of eDreams to be most consistent on Cheapflights vs. eDreams Users can find the same prices on Cali-Guayaquil flight deals on Cheapflights vs. eDreams >95% of the time. Price accuracy is based on data collected from Cali-Guayaquil flight searches over the past month and is updated monthly.
  • Most trusted provider: When it comes to deals on Cali-Guayaquil flights, Cheapflights users trust eDreams the most. eDreams has received a user feedback score of 3 out of 3 stars (3 being the best), meaning they have been trusted the most by Cheapflights users looking for Cali-Guayaquil flight deals. Provider user feedback score is based on Cheapflights searches over the past month and is updated monthly.

Best time to book a flight from Cali to Guayaquil

Have a flexible travel schedule? Discover the best time to fly to Guayaquil from Cali with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Cali to Guayaquil

How far ahead should I book a flight from Cali to Guayaquil?

Use this chart to determine the optimal time to book a round-trip flight from Cali to Guayaquil. Price data was last updated on December 12, 2025.

The best time to book flights from Cali to Guayaquil is 52 days before your desired departure date. The cost of your flight will likely increase significantly if you book two weeks in advance of your flight.

What is the cheapest month to book a flight from Cali to Guayaquil?

Currently, January is the cheapest month in which you can book a flight from Cali to Guayaquil (average of $118). Flying from Cali to Guayaquil in October is currently the most expensive (average of $256). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

Reviews of airlines servicing Guayaquil

Get insights into the airlines that provide service to Guayaquil. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Guayaquil. Reviews last updated December 14, 2025.
Read reviews from past customers who have flown Copa Airlines and Avianca from Cali to Guayaquil. Users can see the overall rating for each airline as well as how each is rated in terms of entertainment options, comfort, food, crew/service, and boarding process.
Copa Airlines
7.6
Good
1,557 reviews

Entertainment

6.8

Crew

8.1

Overall

7.6

Boarding

7.8

Comfort

7.4

Food

6.8

Reviews

1 / 20
10.0
Excellent

Juan Pablo,Sep 2025

MEX - PTY

never better, had a very plesent trip to panama, cant say the same thing of my trip, from panama to santa cruz... it was very poor, unconftrable and boring
Copa Airlines
7.6
Good
1,557 reviews
Copa Airlines
7.6
Good
1,557 reviews

Entertainment

6.8

Crew

8.1

Overall

7.6

Boarding

7.8

Comfort

7.4

Food

6.8

Reviews

1 / 20
10.0
Excellent

Juan Pablo,Sep 2025

MEX - PTY

never better, had a very plesent trip to panama, cant say the same thing of my trip, from panama to santa cruz... it was very poor, unconftrable and boring
Avianca
6.6
Okay
2,485 reviews
Copa Airlines
7.6
Good
1,557 reviews

Entertainment

6.8

Crew

8.1

Overall

7.6

Boarding

7.8

Comfort

7.4

Food

6.8

Reviews

1 / 20
10.0
Excellent

Juan Pablo,Sep 2025

MEX - PTY

never better, had a very plesent trip to panama, cant say the same thing of my trip, from panama to santa cruz... it was very poor, unconftrable and boring

Related info for your journey

Find useful and relevant information for your journey from Cali to Guayaquil. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • How long is the flight from Cali to Guayaquil?

    Airlines like Avianca fly from Cali to Guayaquil in about 6h 10m. The time it takes to get you to your destination can typically vary by up to . Airlines will cover a distance of 462 mi.

  • What are the cheapest airlines flying from Cali to Guayaquil round-trip?

    Cheapflights users have booked flights from Cali to Guayaquil round-trip from $123. Another airline that can offer you cheap pricing is Avianca. You may be able to fly from Cali to Guayaquil for 61% less than the average price by searching for these airlines.

  • Can I find deals for flights from Cali to Guayaquil that include hotel bookings?

    Yes. In addition to deals on Cali to Guayaquil flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Cali to Guayaquil?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Cali to Guayaquil.

  • Can I find deals for business class flights from Cali to Guayaquil?

    Yes. Cheapflights offers flight deals from Cali to Guayaquil by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Cali to Guayaquil?

    Currently, January is the cheapest month in which you can book a flight from Cali to Guayaquil (average of $118). Flying from Cali to Guayaquil in October is currently the most expensive (average of $256). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

Browse thousands of different options on Cheapflights for your next trip

Toggle through the tabs below to find thousands of options on Cheapflights for your next trip.

Top 2 airlines flying from Cali to Guayaquil

Discover the top 2 airlines that operate flights from Cali to Guayaquil. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated December 14, 2025.
AirlineCheapestAverageFlexibilityOn-time
Copa AirlinesCheapest$155Average$306FlexibilityNo cancel feeOn-time70%
AviancaCheapest$228Average$341FlexibilityNo cancel feeOn-time71%

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