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Guayaquil

$175+ Cheap flights from Cali (CLO) to Guayaquil (GYE)

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 12/3. Fares are subject to change and may not be available on all flights or dates of travel.
CLO — GYE
Oct 11 — Oct 181
Sat 10/11
Sat 10/18
1 adult, Economy
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Cheapflights Tip: The best prices from Cali Alfonso B. Aragon Intl to Guayaquil Jose Joaquin de Olmedo are usually found in September or June, booked 74 days in advance, depart on a Wednesday or Thursday and return on a Saturday

Cheap flight deals from Cali to Guayaquil

Discover tips and strategies to find the most affordable flight options for your journey from Cali (CLO) to Guayaquil (GYE). Learn about various techniques such as flexible date searches, comparing prices across and setting up price alerts. Use these methods to find the cheapest flights available for your travel needs. Data last updated September 11, 2025.

Round-trip from

$321
(Copa Airlines)

One-way from

$175
(Avianca)

Popular in

December

Cheapest in

September

Average price

$259
From Cali Alfonso B. Aragon Intl to Guayaquil Jose Joaquin de Olmedo
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One-way flight from Cali Alfonso B. Aragon Intl to Guayaquil Jose Joaquin de Olmedo
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Highest demand for flights based on searches. 1% potential increase in price ($4 potential increase over avg. RT price).
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Cheapest flight prices on average. 1% potential price decrease ($4 potential savings vs. average RT price).
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Average for round-trip flights in September 2025
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Find flight deals from Cali to Guayaquil

Cheapest flights from Cali to Guayaquil
Explore the most affordable flight options available from Cali to Guayaquil. Find the lowest fares from popular airlines and budget airlines, with prices last updated on September 11, 2025.

This Copa Airlines deal was found by Cheapflights users on 9/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Copa Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 11/2012:04 pmCLO - GYE
1 stop11h 51mCopa Airlines
Thu 11/278:30 amGYE - CLO
1 stop5h 41mCopa Airlines
Deal found 9/10$321
This Copa Airlines deal was found by Cheapflights users on 9/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Copa Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/318:48 amCLO - GYE
1 stop14h 49mCopa Airlines
Mon 11/38:30 amGYE - CLO
1 stop5h 41mCopa Airlines
Deal found 9/10$341
This FlightHub deal was found by Cheapflights users on 9/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure FlightHub is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 10/16:50 amCLO - GYE
2 stops10h 48mLATAM Airlines
Fri 10/1011:01 pmGYE - CLO
2 stops16h 53mLATAM Airlines
Deal found 9/11$366
This Avianca deal was found by Cheapflights users on 9/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Avianca is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/96:50 pmCLO - GYE
1 stop4h 30mAvianca
Sun 1/44:40 amGYE - CLO
1 stop4h 50mAvianca
Deal found 9/10$380
This Copa Airlines deal was found by Cheapflights users on 9/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Copa Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 11/94:52 amCLO - GYE
1 stop8h 42mCopa Airlines
Sun 11/164:31 amGYE - CLO
1 stop6h 30mCopa Airlines
Deal found 9/11$392
This Copa Airlines deal was found by Cheapflights users on 9/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Copa Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/912:01 pmCLO - GYE
1 stop11h 36mCopa Airlines
Mon 1/58:34 amGYE - CLO
1 stop5h 36mCopa Airlines
Deal found 9/11$404
This Copa Airlines deal was found by Cheapflights users on 9/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Copa Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 11/412:04 pmCLO - GYE
1 stop11h 51mCopa Airlines
Sat 11/88:30 amGYE - CLO
1 stop5h 41mCopa Airlines
Deal found 9/11$421

Cheapflights Fare Finder

 
Customize your flight search to find flights from Cali to Guayaquil that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated September 11, 2025.
Use the filters below to find and compare flights from Cali to Guayaquil that are best for you.

Fly from

Cali

Fly to

Guayaquil

Route

Depart

Return

Price

CaliGuayaquil

CLO - GYE

CLOGYE

Cali Alfonso B. Aragon Intl

Thu 11/20

12:04 pm-11:55 pm

1 stop11h 51m

Guayaquil Jose Joaquin de Olmedo

Thu 11/27

8:30 am-2:11 pm

1 stop5h 41m

$321

CaliGuayaquil

CLO - GYE

CLOGYE

Cali Alfonso B. Aragon Intl

Fri 10/31

8:48 am-11:37 pm

1 stop14h 49m

Guayaquil Jose Joaquin de Olmedo

Mon 11/3

8:30 am-2:11 pm

1 stop5h 41m

$341

CaliGuayaquil

CLO - GYE

CLOGYE

Cali Alfonso B. Aragon Intl

Wed 2/4

12:03 pm-8:46 pm

1 stop8h 43m

Guayaquil Jose Joaquin de Olmedo

Thu 2/19

8:34 am-5:50 pm

1 stop9h 16m

$371

CaliGuayaquil

CLO - GYE

CLOGYE

Cali Alfonso B. Aragon Intl

Thu 10/9

6:50 pm-11:20 pm

1 stop4h 30m

Guayaquil Jose Joaquin de Olmedo

Sun 1/4

4:40 am-9:30 am

1 stop4h 50m

$380

CaliGuayaquil

CLO - GYE

CLOGYE

Cali Alfonso B. Aragon Intl

Wed 12/3

8:40 am-2:25 pm

1 stop5h 45m

$175

CaliGuayaquil

CLO - GYE

CLOGYE

Cali Alfonso B. Aragon Intl

Fri 10/31

8:48 am-11:37 pm

1 stop14h 49m

$199

Flights are sorted by cheapest round-trip flights first.

Deals found on 9/10

Best time to book a flight from Cali to Guayaquil

Have a flexible travel schedule? Discover the best time to fly to Guayaquil from Cali with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Cali to Guayaquil

How far ahead should I book a flight from Cali to Guayaquil?

Use this chart to determine the optimal time to book a round-trip flight from Cali to Guayaquil. Price data was last updated on August 29, 2025.

The best time to book flights from Cali to Guayaquil is 73 days before your desired departure date. The cost of your flight will likely increase significantly if you book two weeks in advance of your flight.

What is the cheapest month to book a flight from Cali to Guayaquil?

Currently, April is the cheapest month in which you can book a flight from Cali to Guayaquil (average of $440). Flying from Cali to Guayaquil in December is currently the most expensive (average of $722). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

What is the cheapest time of day to fly from CLO to GYE?

Find hourly flight availability from Cali to Guayaquil. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated September 11, 2025.

It’s optimal to fly from Cali to Guayaquil in the afternoon. By choosing this option you can save up to 4% on the cost of your flight, compared to a flight in the morning.

Reviews of airlines servicing Guayaquil

Get insights into the airlines that provide service to Guayaquil. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Guayaquil. Reviews last updated September 11, 2025.
Read reviews from past customers who have flown Copa Airlines and Avianca from Cali to Guayaquil. Users can see the overall rating for each airline as well as how each is rated in terms of entertainment options, comfort, food, crew/service, and boarding process.
Copa Airlines
7.6
Good
1,531 reviews

Entertainment

6.8

Food

6.8

Boarding

7.8

Comfort

7.4

Overall

7.6

Crew

8.1

Reviews

1 / 20
4.0
Okay

Juan Pablo,Sep 2025

PTY - VVI

not a good expirience, the plane was packed, the seats wear very unconftrable, coudent conect with the entratainmente service on the plane, the onboarding was in charge of a very angry lady i really had a unplesent trip
Copa Airlines
7.6
Good
1,531 reviews
Copa Airlines
7.6
Good
1,531 reviews

Entertainment

6.8

Food

6.8

Boarding

7.8

Comfort

7.4

Overall

7.6

Crew

8.1

Reviews

1 / 20
4.0
Okay

Juan Pablo,Sep 2025

PTY - VVI

not a good expirience, the plane was packed, the seats wear very unconftrable, coudent conect with the entratainmente service on the plane, the onboarding was in charge of a very angry lady i really had a unplesent trip
Avianca
6.7
Okay
2,436 reviews
Copa Airlines
7.6
Good
1,531 reviews

Entertainment

6.8

Food

6.8

Boarding

7.8

Comfort

7.4

Overall

7.6

Crew

8.1

Reviews

1 / 20
4.0
Okay

Juan Pablo,Sep 2025

PTY - VVI

not a good expirience, the plane was packed, the seats wear very unconftrable, coudent conect with the entratainmente service on the plane, the onboarding was in charge of a very angry lady i really had a unplesent trip

Related info for your journey

Find useful and relevant information for your journey from Cali to Guayaquil. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • How long is the flight from Cali to Guayaquil?

    Airlines like Copa Airlines fly from Cali to Guayaquil in about 11h 51m. The time it takes to get you to your destination can typically vary by up to . Airlines will cover a distance of 462 mi.

  • What are the cheapest airlines flying from Cali to Guayaquil round-trip?

    Cheapflights users have booked flights from Cali to Guayaquil round-trip from $155. Another airline that can offer you cheap pricing is Avianca. You may be able to fly from Cali to Guayaquil for 47% less than the average price by searching for these airlines.

  • Can I find deals for flights from Cali to Guayaquil that include hotel bookings?

    Yes. In addition to deals on Cali to Guayaquil flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Cali to Guayaquil?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Cali to Guayaquil.

  • Can I find deals for business class flights from Cali to Guayaquil?

    Yes. Cheapflights offers flight deals from Cali to Guayaquil by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Cali to Guayaquil?

    Currently, April is the cheapest month in which you can book a flight from Cali to Guayaquil (average of $440). Flying from Cali to Guayaquil in December is currently the most expensive (average of $722). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

Browse thousands of different options on Cheapflights for your next trip

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Top 2 airlines flying from Cali to Guayaquil

Discover the top 2 airlines that operate flights from Cali to Guayaquil. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated September 11, 2025.
AirlineCheapestAverageFlexibilityOn-time
Copa AirlinesCheapest$155Average$306FlexibilityNo cancel feeOn-time70%
AviancaCheapest$177Average$305FlexibilityNo cancel feeOn-time71%

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