
Most accurate provider | eDreams 3 stars  | 
|---|---|
Most trusted provider | eDreams 3 stars  | 
Round-trip from | $283 (Priceline)  | 
One-way from | $155 (Copa Airlines)  | 
Popular in | February | 
Cheapest in | May | 
Average price | $291 | 
Good round-trip deal | $290 or less | 
Good one-way deal | $155 or less | 
Fly from
Fly to
Route
Depart
Return
Price
Panama CityGuatemala City
PTY - GUA
PTYGUA
Panama City Tocumen Intl
Wed 3/4
10:10 am-11:36 am
Nonstop2h 26m
Guatemala City La Aurora
Sat 3/7
10:34 am-2:03 pm
Nonstop2h 29m
Panama CityGuatemala City
PTY - GUA
PTYGUA
Panama City Tocumen Intl
Fri 12/19
7:31 am-8:56 am
Nonstop2h 25m
Guatemala City La Aurora
Tue 12/23
6:24 am-11:09 am
1 stop3h 45m
Panama CityGuatemala City
PTY - GUA
PTYGUA
Panama City Tocumen Intl
Fri 11/28
7:57 am-9:20 am
Nonstop2h 23m
Guatemala City La Aurora
Thu 12/4
2:26 am-5:55 am
Nonstop2h 29m
Panama CityGuatemala City
PTY - GUA
PTYGUA
Panama City Tocumen Intl
Fri 12/5
7:31 am-8:56 am
Nonstop2h 25m
Guatemala City La Aurora
Mon 12/8
4:28 pm-7:55 pm
Nonstop2h 27m
Panama CityGuatemala City
PTY - GUA
PTYGUA
Panama City Tocumen Intl
Wed 3/11
10:10 am-11:36 am
Nonstop2h 26m
Guatemala City La Aurora
Sun 3/15
1:16 pm-4:39 pm
Nonstop2h 23m
Panama CityGuatemala City
PTY - GUA
PTYGUA
Panama City Tocumen Intl
Thu 12/11
8:11 am-9:34 am
Nonstop2h 23m
Guatemala City La Aurora
Tue 12/16
6:24 am-11:09 am
1 stop3h 45m
Panama CityGuatemala City
PTY - GUA
PTYGUA
Panama City Tocumen Intl
Wed 2/4
7:31 am-8:55 am
Nonstop2h 24m
Guatemala City La Aurora
Mon 2/9
4:24 am-7:50 am
Nonstop2h 26m
Panama CityGuatemala City
PTY - GUA
PTYGUA
Panama City Tocumen Intl
Fri 1/16
8:11 am-9:34 am
Nonstop2h 23m
Guatemala City La Aurora
Sat 1/17
4:24 am-7:50 am
Nonstop2h 26m
Panama CityGuatemala City
PTY - GUA
PTYGUA
Panama City Tocumen Intl
Fri 2/13
8:11 am-9:34 am
Nonstop2h 23m
Guatemala City La Aurora
Wed 2/18
10:34 am-2:03 pm
Nonstop2h 29m
Panama CityGuatemala City
PTY - GUA
PTYGUA
Panama City Tocumen Intl
Mon 1/5
7:31 am-8:55 am
Nonstop2h 24m
Guatemala City La Aurora
Sun 1/11
10:34 am-2:03 pm
Nonstop2h 29m
Currently, April is the cheapest month in which you can book a flight from Panama to Guatemala City (average of $134). Flying from Panama to Guatemala City in January is currently the most expensive (average of $197). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.
It’s typically best to fly out from Panama to Guatemala City at noon. Doing so could potentially save you 22% on the flight price compared to flying in the morning, which is usually more expensive.
The most flights from PA0 to GUA are scheduled on a Monday (16 on average). You will have fewer flight options on Friday, which is when the least amount of flights are scheduled (8 on average).
Entertainment
Boarding
Comfort
Food
Overall
Crew
Reviews
Juan Pablo,Sep 2025
PTY - VVI
Entertainment
Boarding
Comfort
Food
Overall
Crew
Reviews
Juan Pablo,Sep 2025
PTY - VVI
Entertainment
Boarding
Comfort
Food
Overall
Crew
Reviews
Juan Pablo,Sep 2025
PTY - VVI
| Airline | Cheapest | Average | Flexibility | On-time | 
|---|---|---|---|---|
| Cheapest$194 | Average$294 | FlexibilityNo cancel fee | On-time70% | |
| Cheapest$194 | Average$262 | FlexibilityNo cancel fee | On-time71% |