Guanajuato

$220+ Cheap flights from Des Moines (DSM) to Guanajuato, Mexico, Mexico

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 5/4. Fares are subject to change and may not be available on all flights or dates of travel.
DSM — BJX
Mar 18 — Mar 251
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Cheap flight deals from Des Moines to Guanajuato

Cheapest flights from Des Moines to Guanajuato
Explore the most affordable flight options available from Des Moines to Guanajuato. Find the lowest fares from popular airlines and budget airlines, with prices last updated on February 16, 2026.

This American Airlines deal was found by Cheapflights users on 2/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 4/15:05 am
DSM
-
BJX
1 stop16h 53m
American Airlines
Wed 4/86:01 am
BJX
-
DSM
1 stop7h 46m
American Airlines
Deal found 2/15$528
This American Airlines deal was found by Cheapflights users on 2/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 3/2811:26 am
DSM
-
BJX
1 stop10h 44m
American Airlines
Sat 4/48:00 am
BJX
-
DSM
1 stop25h 34m
American Airlines
Deal found 2/14$567
This Delta deal was found by Cheapflights users on 2/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 8/116:20 am
DSM
-
BJX
2 stops12h 50m
Delta
Tue 8/255:55 am
BJX
-
DSM
2 stops15h 31m
Delta
Deal found 2/12$571
This Delta deal was found by Cheapflights users on 2/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 4/147:00 am
DSM
-
BJX
2 stops14h 45m
Delta
Wed 4/229:20 am
BJX
-
DSM
1 stop7h 25m
Delta
Deal found 2/14$580
This United Airlines deal was found by Cheapflights users on 2/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 3/175:30 am
DSM
-
BJX
2 stops13h 14m
United Airlines
Tue 4/75:00 am
BJX
-
DSM
2 stops10h 10m
United Airlines
Deal found 2/15$585
This Delta deal was found by Cheapflights users on 2/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 8/86:20 am
DSM
-
BJX
2 stops12h 50m
Delta
Tue 8/257:25 am
BJX
-
DSM
2 stops14h 01m
Delta
Deal found 2/12$591
This Delta deal was found by Cheapflights users on 2/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 5/97:06 am
DSM
-
BJX
2 stops11h 14m
Delta
Mon 5/189:20 am
BJX
-
DSM
1 stop12h 12m
Delta
Deal found 2/14$600
This Delta deal was found by Cheapflights users on 2/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 8/115:45 am
DSM
-
BJX
1 stop13h 25m
Delta
Mon 8/248:20 am
BJX
-
DSM
1 stop13h 06m
Delta
Deal found 2/12$607
This Delta deal was found by Cheapflights users on 2/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 8/85:45 am
DSM
-
BJX
1 stop13h 25m
Delta
Sun 8/238:20 am
BJX
-
DSM
1 stop13h 06m
Delta
Deal found 2/12$611
This Delta deal was found by Cheapflights users on 2/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 8/106:20 am
DSM
-
BJX
2 stops12h 50m
Delta
Wed 8/268:20 am
BJX
-
DSM
2 stops11h 25m
Delta
Deal found 2/12$616

Find flight deals from Des Moines to Guanajuato

Keep the following information in mind while searching for Des Moines to Guanajuato flight deals. Data was last updated February 16, 2026.

Most accurate provider

FlightHub
3 stars

Most trusted provider

FlightHub
3 stars

Round-trip from

$528
(American Airlines)

One-way from

$220
(Kiwi.com)

Popular in

December

Cheapest in

April

Average price

$560
Provider with most accurate pricing for Des Moines-León Del Bajio flight deals.
Provider most trusted by Cheapflights users for Des Moines-León Del Bajio flights.
From Des Moines to Guanajuato
One-way flight from Des Moines to Guanajuato
Highest demand for flights based on searches. 15% potential increase in price ($126 potential increase over avg. RT price).
Cheapest flight prices on average. 4% potential price decrease ($28 potential savings vs. average RT price).
Average for round-trip flights in February 2026

Cheapflights Fare Finder

 
Customize your flight search to find flights from Des Moines to Guanajuato that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated February 16, 2026.
Use the filters below to find and compare flights from Des Moines to Guanajuato that are best for you.

Fly from

Des Moines

Fly to

Guanajuato

Route

Depart

Return

Price

Des MoinesLeón

DSM - BJX

DSMBJX

Des Moines

Wed 4/1

5:05 am-8:58 pm

1 stop16h 53m

León Del Bajio

Wed 4/8

6:01 am-2:47 pm

1 stop7h 46m

$528

Des MoinesLeón

DSM - BJX

DSMBJX

Des Moines

Sat 3/28

11:26 am-9:10 pm

1 stop10h 44m

León Del Bajio

Sat 4/4

8:00 am-10:34 am

1 stop25h 34m

$567

Des MoinesLeón

DSM - BJX

DSMBJX

Des Moines

Tue 8/11

11:04 am-6:10 pm

1 stop8h 06m

León Del Bajio

Thu 8/27

8:20 am-10:15 am

2 stops24h 55m

$571

Des MoinesLeón

DSM - BJX

DSMBJX

Des Moines

Thu 8/13

11:04 am-6:10 pm

1 stop8h 06m

León Del Bajio

Thu 8/27

8:20 am-9:19 am

2 stops23h 59m

$571

Des MoinesLeón

DSM - BJX

DSMBJX

Des Moines

Mon 8/10

5:45 am-6:10 pm

1 stop13h 25m

León Del Bajio

Wed 8/26

8:20 am-5:42 pm

1 stop8h 22m

$571

Des MoinesLeón

DSM - BJX

DSMBJX

Des Moines

Wed 8/12

11:04 am-6:10 pm

1 stop8h 06m

León Del Bajio

Thu 8/27

5:55 am-10:26 pm

2 stops15h 31m

$571

Des MoinesLeón

DSM - BJX

DSMBJX

Des Moines

Wed 8/12

11:04 am-6:10 pm

1 stop8h 06m

León Del Bajio

Wed 8/26

8:20 am-5:42 pm

1 stop8h 22m

$571

Des MoinesLeón

DSM - BJX

DSMBJX

Des Moines

Mon 8/10

5:45 am-6:10 pm

1 stop13h 25m

León Del Bajio

Thu 8/27

7:25 am-10:26 pm

2 stops14h 01m

$571

Des MoinesLeón

DSM - BJX

DSMBJX

Des Moines

Mon 5/4

2:20 pm-11:20 pm

2 stops34h 00m

$220

Des MoinesLeón

DSM - BJX

DSMBJX

Des Moines

Tue 2/24

11:17 am-10:10 pm

1 stop10h 53m

$313

Flights are sorted by cheapest round-trip flights first.

Deals found on 2/13

Showing 1-10 of 14 results
1
2

Best time to book a flight from Des Moines to Guanajuato

Have a flexible travel schedule? Discover the best time to fly to Guanajuato from Des Moines with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Des Moines to Guanajuato

What is the cheapest month to book a flight from Des Moines to Guanajuato?

Currently, April is the cheapest month in which you can book a flight from Des Moines to Guanajuato (average of $432). Flying from Des Moines to Guanajuato in December is currently the most expensive (average of $743). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

Reviews of airlines servicing Guanajuato

Get insights into the airlines that provide service to Guanajuato. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Guanajuato. Reviews last updated February 16, 2026.
Read reviews from past customers who have flown United Airlines and American Airlines from Des Moines to Guanajuato. Users can see the overall rating for each airline as well as how each is rated in terms of entertainment options, comfort, food, crew/service, and boarding process.

Comfort

7.3

Overall

7.4

Food

6.6

Entertainment

7.1

Boarding

7.7

Crew

8.1

Reviews

1 / 20
10.0
Excellent

Dane,Jan 2026

TYS - IAD

It was a short flight, so no time for amenities. Just glad everything was quick and easy from boarding to arriving at my destination with my family

Comfort

7.3

Overall

7.4

Food

6.6

Entertainment

7.1

Boarding

7.7

Crew

8.1

Reviews

1 / 20
10.0
Excellent

Dane,Jan 2026

TYS - IAD

It was a short flight, so no time for amenities. Just glad everything was quick and easy from boarding to arriving at my destination with my family

Comfort

7.3

Overall

7.4

Food

6.6

Entertainment

7.1

Boarding

7.7

Crew

8.1

Reviews

1 / 20
10.0
Excellent

Dane,Jan 2026

TYS - IAD

It was a short flight, so no time for amenities. Just glad everything was quick and easy from boarding to arriving at my destination with my family

Related info for your journey

Find useful and relevant information for your journey from Des Moines to Guanajuato. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.
  • What airport do you fly from for flights from Des Moines to Guanajuato?

    If you book a flight to Guanajuato from Des Moines, you will be flying from Des Moines, which is the city’s only airport. Des Moines (DSM) is located 3.6 mi from the center of Des Moines. There are 0 flights from Des Moines to Guanajuato per day from 2 different airlines.

  • How long is the flight from Des Moines to Guanajuato?

    A quick flight from Des Moines to Guanajuato can take about 8h 06m. American Airlines provides one of the quickest options available for as low as $571. Des Moines and Guanajuato are separated by a distance of 1490 mi. When browsing for deals, the options you’ll see will be for both nonstop flights and flights with stops.

  • Can I find deals for flights from Des Moines to Guanajuato that include hotel bookings?

    Yes. In addition to deals on Des Moines to Guanajuato flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Des Moines to Guanajuato?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Des Moines to Guanajuato.

  • Can I find deals for business class flights from Des Moines to Guanajuato?

    Yes. Cheapflights offers flight deals from Des Moines to Guanajuato by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Des Moines to Guanajuato?

    Currently, April is the cheapest month in which you can book a flight from Des Moines to Guanajuato (average of $432). Flying from Des Moines to Guanajuato in December is currently the most expensive (average of $743). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

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Alternative routes for Des Moines to Guanajuato

See prices for flight routes from nearby airports that may be better suited for you.

Top 2 airlines flying from Des Moines to Guanajuato

Discover the top 2 airlines that operate flights from Des Moines to Guanajuato. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated February 16, 2026.
AirlineCheapestAverageFlexibilityOn-time
American AirlinesCheapest$486Average$784FlexibilityNo cancel feeOn-time71%
United AirlinesCheapest$517Average$653FlexibilityNo cancel feeOn-time69%

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