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$2,253+ Cheap flights from Knoxville (TYS) to Guam

This is the cheapest round-trip flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 10/23. Fares are subject to change and may not be available on all flights or dates of travel.
TYS — GUM
Jul 24 — Jul 311
Fri 7/24
Fri 7/31
1 adult, Economy
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Cheap flight deals from Knoxville to Guam

Cheapest flights from Knoxville to Guam
Explore the most affordable flight options available from Knoxville to Guam. Find the lowest fares from popular airlines and budget airlines, with prices last updated on June 24, 2026.

This Delta deal was found by Cheapflights users on 6/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/237:00 am
TYS
-
GUM
2 stops41h 35m
Delta
Tue 10/274:50 pm
GUM
-
TYS
2 stops44h 56m
Delta
Deal found 6/22$2,253
This United Airlines deal was found by Cheapflights users on 6/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 11/87:20 pm
TYS
-
GUM
2 stops42h 20m
United Airlines
Thu 11/127:45 am
GUM
-
TYS
2 stops28h 57m
United Airlines
Deal found 6/23$2,263
This United Airlines deal was found by Cheapflights users on 6/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/2310:42 am
TYS
-
GUM
3 stops42h 18m
United Airlines
Tue 10/277:45 am
GUM
-
TYS
2 stops28h 53m
United Airlines
Deal found 6/22$2,318
This United Airlines deal was found by Cheapflights users on 6/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 9/96:00 am
TYS
-
GUM
2 stops22h 05m
United Airlines
Sun 9/137:35 pm
GUM
-
TYS
2 stops41h 14m
United Airlines
Deal found 6/22$2,384
This United Airlines deal was found by Cheapflights users on 6/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 6/246:00 am
TYS
-
GUM
2 stops22h 05m
United Airlines
Fri 6/267:30 pm
GUM
-
TYS
2 stops41h 04m
United Airlines
Deal found 6/20$3,004

Find flight deals from Knoxville to Guam

Keep the following information in mind while searching for Knoxville to Guam flight deals. Data was last updated June 24, 2026.

Most accurate provider

FlightHub
3 stars

Most trusted provider

FlightHub
3 stars

Round-trip from

$2,253
(Delta)
Provider with most accurate pricing for Knoxville McGhee Tyson-Tamuning Guam Intl flight deals.
Search Deals
Provider most trusted by Cheapflights users for Knoxville McGhee Tyson-Tamuning Guam Intl flights.
Search Deals
From Knoxville McGhee Tyson to Guam
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Cheapflights Fare Finder

 
Customize your flight search to find flights from Knoxville to Guam that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated June 24, 2026.
Use the filters below to find and compare flights from Knoxville to Guam that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

Cheapest round-trip

KnoxvilleTamuning

TYS - GUM

TYSGUM

Knoxville McGhee Tyson

Fri 10/23

7:00 am-2:35 pm

2 stops41h 35m

Tamuning Guam Intl

Tue 10/27

4:50 pm-11:46 pm

2 stops44h 56m

$2,253

KnoxvilleTamuning

TYS - GUM

TYSGUM

Knoxville McGhee Tyson

Sun 11/8

7:20 pm-4:40 am

2 stops42h 20m

Tamuning Guam Intl

Thu 11/12

7:45 am-9:42 pm

2 stops28h 57m

$2,263

KnoxvilleTamuning

TYS - GUM

TYSGUM

Knoxville McGhee Tyson

Fri 10/23

10:42 am-7:00 pm

3 stops42h 18m

Tamuning Guam Intl

Tue 10/27

7:45 am-10:38 pm

2 stops28h 53m

$2,318
Quickest round-trip

KnoxvilleTamuning

TYS - GUM

TYSGUM

Knoxville McGhee Tyson

Wed 9/9

6:00 am-6:05 pm

2 stops22h 05m

Tamuning Guam Intl

Sun 9/13

7:35 pm-10:49 pm

2 stops41h 14m

$2,384

Flights are sorted by cheapest round-trip flights first.

Deals found on 6/22

Sorted by cheapest first

Best time to book a flight from Knoxville to Guam

Have a flexible travel schedule? Discover the best time to fly to Guam from Knoxville with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Knoxville to Guam
No data available for this route at this time. Please check back soon.

Related info for your journey

Find useful and relevant information for your journey from Knoxville to Guam. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • What airport do you fly from for flights from Knoxville to Guam?

    If you book a flight to Guam from Knoxville, you will be flying from McGhee Tyson, which is the city’s only airport. Knoxville McGhee Tyson (TYS) is located 11.3 mi from the center of Knoxville.

  • How long is the flight from Knoxville to Guam?

    Airlines like Delta and United Airlines fly from Knoxville to Guam in about 41h 35m. The time it takes to get you to your destination can typically vary by up to 45m. The distance from Knoxville to Guam is about 7770 mi. When browsing for deals, the options you’ll see will be for both nonstop flights and flights with stops.

  • Can I find deals for flights from Knoxville to Guam that include hotel bookings?

    Yes. In addition to deals on Knoxville to Guam flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Knoxville to Guam?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Knoxville to Guam.

  • Can I find deals for business class flights from Knoxville to Guam?

    Yes. Cheapflights offers flight deals from Knoxville to Guam by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

See more FAQs

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