HomeSearch by dateVacation packagesHotelsFlight dealsCar rentalTravel tips & news
Greenville

$175+ Cheap flights from Portland to Greenville (PDX - GSP)

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 10/11. Fares are subject to change and may not be available on all flights or dates of travel.
PDX — GSP
Oct 11 — Oct 181
Sat 10/11
Sat 10/18
1 adult, Economy
We work with more than 300 partners to bring you better travel deals

Find cheap flights from Portland to Greenville with Cheapflights

1. Tell us where you want to go

Enter your travel information like dates, passengers, trip type (one-way or round trip), and preferred cabin class then click “Find deals”

2. Select your favorite providers

We find the providers serving your travel needs. Choose up to four travel providers to compare side-by-side for flights, hotels, or car rentals.

3. Compare prices and book

Review each provider’s pricing and select the best option for you! Book through your favorite provider’s website for a seamless experience.

Cheapflights Tip: The best prices from Portland to Greenville are usually found in February or September, booked 61 days in advance, depart on a Wednesday or Tuesday and return on a Friday

Cheap flight deals from Portland to Greenville

Discover tips and strategies to find the most affordable flight options for your journey from Portland (PDX) to Greenville (GSP). Learn about various techniques such as flexible date searches, comparing prices across and setting up price alerts. Use these methods to find the cheapest flights available for your travel needs. Data last updated September 11, 2025.

Round-trip from

$249
(Delta)

One-way from

$175
(United Airlines)

Popular in

December

Cheapest in

February

Average price

$438
From Portland to Greenville
Search Deals
One-way flight from Portland to Greenville
Search Deals
Highest demand for flights based on searches. 4% potential increase in price ($27 potential increase over avg. RT price).
Search Deals
Cheapest flight prices on average. 2% potential price decrease ($14 potential savings vs. average RT price).
Search Deals
Average for round-trip flights in September 2025
Search Deals

Find flight deals from Portland to Greenville

Cheapest flights from Portland to Greenville
Explore the most affordable flight options available from Portland to Greenville. Find the lowest fares from popular airlines and budget airlines, with prices last updated on September 11, 2025.

This Delta deal was found by Cheapflights users on 9/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 10/15:01 pmPDX - GSP
2 stops13h 12mDelta
Sat 10/115:16 pmGSP - PDX
1 stop7h 52mDelta
Deal found 9/9$254
This Delta deal was found by Cheapflights users on 9/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 10/85:07 pmPDX - GSP
2 stops12h 52mDelta
Wed 10/159:54 amGSP - PDX
2 stops12h 06mDelta
Deal found 9/9$259
This Delta deal was found by Cheapflights users on 9/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/1710:10 pmPDX - GSP
1 stop8h 59mDelta
Wed 10/225:30 amGSP - PDX
1 stop7h 46mDelta
Deal found 9/10$297
This American Airlines deal was found by Cheapflights users on 9/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 10/89:52 pmPDX - GSP
1 stop9h 53mAmerican Airlines
Wed 10/156:09 pmGSP - PDX
1 stop8h 20mAmerican Airlines
Deal found 9/9$313
This Delta deal was found by Cheapflights users on 9/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 10/1410:10 pmPDX - GSP
1 stop7h 49mDelta
Wed 10/225:30 amGSP - PDX
1 stop7h 46mDelta
Deal found 9/10$334
This Delta deal was found by Cheapflights users on 9/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 10/1510:23 amPDX - GSP
2 stops10h 32mDelta
Sat 10/186:00 amGSP - PDX
1 stop7h 16mDelta
Deal found 9/10$339
This United Airlines deal was found by Cheapflights users on 9/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/1711:59 pmPDX - GSP
1 stop8h 47mUnited Airlines
Mon 10/203:55 pmGSP - PDX
1 stop9h 30mUnited Airlines
Deal found 9/10$345
This Delta deal was found by Cheapflights users on 9/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 10/196:00 amPDX - GSP
1 stop7h 31mDelta
Wed 10/225:30 amGSP - PDX
1 stop7h 46mDelta
Deal found 9/10$348
This American Airlines deal was found by Cheapflights users on 9/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 10/1511:59 pmPDX - GSP
1 stop8h 27mAmerican Airlines
Wed 10/226:09 pmGSP - PDX
1 stop8h 20mAmerican Airlines
Deal found 9/10$349
This Delta deal was found by Cheapflights users on 9/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/1710:10 pmPDX - GSP
1 stop7h 49mDelta
Thu 10/235:30 amGSP - PDX
2 stops10h 19mDelta
Deal found 9/10$350

Cheapflights Fare Finder

 
Customize your flight search to find flights from Portland to Greenville that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated September 11, 2025.
Use the filters below to find and compare flights from Portland to Greenville that are best for you.

Fly from

Portland

Fly to

Greenville

Route

Depart

Return

Price

PortlandGreenville

PDX - GSP

PDXGSP

Portland

Wed 10/1

5:01 pm-9:13 am

2 stops13h 12m

Greenville

Sat 10/11

5:16 pm-10:08 pm

1 stop7h 52m

$254

PortlandGreenville

PDX - GSP

PDXGSP

Portland

Wed 10/8

5:07 pm-8:59 am

2 stops12h 52m

Greenville

Wed 10/15

9:54 am-7:00 pm

2 stops12h 06m

$259

PortlandGreenville

PDX - GSP

PDXGSP

Portland

Fri 10/17

10:10 pm-10:09 am

1 stop8h 59m

Greenville

Wed 10/22

5:30 am-10:16 am

1 stop7h 46m

$297

PortlandGreenville

PDX - GSP

PDXGSP

Portland

Tue 10/14

10:10 pm-8:59 am

1 stop7h 49m

Greenville

Sat 10/18

6:00 am-10:16 am

1 stop7h 16m

$334

PortlandGreenville

PDX - GSP

PDXGSP

Portland

Sat 10/18

10:10 pm-8:59 am

1 stop7h 49m

Greenville

Tue 10/21

5:30 am-10:16 am

1 stop7h 46m

$334

PortlandGreenville

PDX - GSP

PDXGSP

Portland

Wed 10/15

10:23 am-11:55 pm

2 stops10h 32m

Greenville

Wed 10/22

5:30 am-10:16 am

1 stop7h 46m

$339

PortlandGreenville

PDX - GSP

PDXGSP

Portland

Fri 10/17

11:59 pm-11:46 am

1 stop8h 47m

Greenville

Mon 10/20

3:55 pm-10:25 pm

1 stop9h 30m

$345

PortlandGreenville

PDX - GSP

PDXGSP

Portland

Tue 10/14

7:00 am-4:53 pm

1 stop6h 53m

Greenville

Wed 10/22

12:21 pm-12:28 am

2 stops15h 07m

$354

PortlandGreenville

PDX - GSP

PDXGSP

Portland

Tue 10/14

7:35 pm-11:46 am

2 stops13h 11m

Greenville

Sat 10/18

12:21 pm-10:45 pm

2 stops13h 24m

$359

PortlandGreenville

PDX - GSP

PDXGSP

Portland

Sat 10/11

10:40 am-11:46 pm

1 stop10h 06m

$175

Flights are sorted by cheapest round-trip flights first.

Deals found on 9/11

Showing 1-10 of 18 results
1
2

Best time to book a flight from Portland to Greenville

Have a flexible travel schedule? Discover the best time to fly to Greenville from Portland with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Portland to Greenville

How far ahead should I book a flight from Portland to Greenville?

Use this chart to determine the optimal time to book a round-trip flight from Portland to Greenville. Price data was last updated on August 29, 2025.

The best time to book flights from Portland to Greenville is 61 days before your desired departure date. The cost of your flight will likely increase significantly if you book two weeks in advance of your flight.

What is the cheapest month to book a flight from Portland to Greenville?

Currently, August is the cheapest month in which you can book a flight from Portland to Greenville (average of $322). Flying from Portland to Greenville in March is currently the most expensive (average of $386). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

What is the cheapest time of day to fly from PDX to GSP?

Find hourly flight availability from Portland to Greenville. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated September 11, 2025.

When flying from Portland to Greenville, the time of day you fly usually plays a role in the price. Save by searching for a flight at noon, which can drop the price by up to 24% versus a flight in the afternoon.

Reviews of airlines servicing Greenville

Get insights into the airlines that provide service to Greenville. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Greenville. Reviews last updated September 11, 2025.
Get a feel of what it's like to fly with Alaska Airlines, Southwest, and Delta from Portland to Greenville by reading reviews from past customers. Users have also rated airlines in terms of entertainment options, comfort, food, crew/service, and boarding process.
Alaska Airlines
8.0
Very good
10,000 reviews

Entertainment

7.0

Food

7.1

Boarding

8.1

Comfort

7.8

Overall

8.0

Crew

8.5

Reviews

1 / 20
6.0
Good

Hannah,Aug 2025

SFO - SAN

Ticket said TSA pre check, but then the TSA agent said that Alaska Airlines has not actually entered the pre check information for the ticket, so I had to use regular security. During boarding, I have a disability and need to board early. The Alaska Airlines employee announced disability boarding, but then immediately announced 2 other groups to board, so I still had to fight the crowds. On the plane, the stewardess was brusk and rude. Seats were very uncomfortable, especially on lower back.
Alaska Airlines
8.0
Very good
10,000 reviews
Alaska Airlines
8.0
Very good
10,000 reviews

Entertainment

7.0

Food

7.1

Boarding

8.1

Comfort

7.8

Overall

8.0

Crew

8.5

Reviews

1 / 20
6.0
Good

Hannah,Aug 2025

SFO - SAN

Ticket said TSA pre check, but then the TSA agent said that Alaska Airlines has not actually entered the pre check information for the ticket, so I had to use regular security. During boarding, I have a disability and need to board early. The Alaska Airlines employee announced disability boarding, but then immediately announced 2 other groups to board, so I still had to fight the crowds. On the plane, the stewardess was brusk and rude. Seats were very uncomfortable, especially on lower back.
Southwest
8.0
Very good
4,248 reviews
Alaska Airlines
8.0
Very good
10,000 reviews

Entertainment

7.0

Food

7.1

Boarding

8.1

Comfort

7.8

Overall

8.0

Crew

8.5

Reviews

1 / 20
6.0
Good

Hannah,Aug 2025

SFO - SAN

Ticket said TSA pre check, but then the TSA agent said that Alaska Airlines has not actually entered the pre check information for the ticket, so I had to use regular security. During boarding, I have a disability and need to board early. The Alaska Airlines employee announced disability boarding, but then immediately announced 2 other groups to board, so I still had to fight the crowds. On the plane, the stewardess was brusk and rude. Seats were very uncomfortable, especially on lower back.
Delta
8.0
Very good
7,960 reviews
Alaska Airlines
8.0
Very good
10,000 reviews

Entertainment

7.0

Food

7.1

Boarding

8.1

Comfort

7.8

Overall

8.0

Crew

8.5

Reviews

1 / 20
6.0
Good

Hannah,Aug 2025

SFO - SAN

Ticket said TSA pre check, but then the TSA agent said that Alaska Airlines has not actually entered the pre check information for the ticket, so I had to use regular security. During boarding, I have a disability and need to board early. The Alaska Airlines employee announced disability boarding, but then immediately announced 2 other groups to board, so I still had to fight the crowds. On the plane, the stewardess was brusk and rude. Seats were very uncomfortable, especially on lower back.
United Airlines
7.4
Good
8,937 reviews
Alaska Airlines
8.0
Very good
10,000 reviews

Entertainment

7.0

Food

7.1

Boarding

8.1

Comfort

7.8

Overall

8.0

Crew

8.5

Reviews

1 / 20
6.0
Good

Hannah,Aug 2025

SFO - SAN

Ticket said TSA pre check, but then the TSA agent said that Alaska Airlines has not actually entered the pre check information for the ticket, so I had to use regular security. During boarding, I have a disability and need to board early. The Alaska Airlines employee announced disability boarding, but then immediately announced 2 other groups to board, so I still had to fight the crowds. On the plane, the stewardess was brusk and rude. Seats were very uncomfortable, especially on lower back.
American Airlines
7.2
Good
10,000 reviews
Alaska Airlines
8.0
Very good
10,000 reviews

Entertainment

7.0

Food

7.1

Boarding

8.1

Comfort

7.8

Overall

8.0

Crew

8.5

Reviews

1 / 20
6.0
Good

Hannah,Aug 2025

SFO - SAN

Ticket said TSA pre check, but then the TSA agent said that Alaska Airlines has not actually entered the pre check information for the ticket, so I had to use regular security. During boarding, I have a disability and need to board early. The Alaska Airlines employee announced disability boarding, but then immediately announced 2 other groups to board, so I still had to fight the crowds. On the plane, the stewardess was brusk and rude. Seats were very uncomfortable, especially on lower back.

Related info for your journey

Find useful and relevant information for your journey from Portland to Greenville. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • How long is the flight from Portland to Greenville?

    A quick flight from Portland to Greenville can take about 13h 12m. Delta provides one of the quickest options available for as low as $254. Airlines will cover a distance of 2225 mi.

  • What are the cheapest airlines flying from Portland to Greenville round-trip?

    Flying on Delta is currently your cheapest option to Greenville, with prices starting at $302. Additional round-trip tickets that might be worth considering are offered by United Airlines and American Airlines, with the lowest prices starting at $311 and $350, respectively. Delta is priced at 42% lower than the current average price of a flight leaving 3 months from now.

  • What are the cheapest airlines to fly from Portland to Greenville one-way?

    One-way options have recently been found by users for as low as $175 on United Airlines. Other airlines that offer cheap prices include Delta from $215 and American Airlines from $220 one-way.

  • Can I find deals for flights from Portland to Greenville that include hotel bookings?

    Yes. In addition to deals on Portland to Greenville flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Portland to Greenville?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Portland to Greenville.

  • Can I find deals for business class flights from Portland to Greenville?

    Yes. Cheapflights offers flight deals from Portland to Greenville by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Portland to Greenville?

    Currently, August is the cheapest month in which you can book a flight from Portland to Greenville (average of $322). Flying from Portland to Greenville in March is currently the most expensive (average of $386). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

Traveling to a place near Greenville?

Book flights to Greenville if you plan to visit one of these locations
Simpsonville
Duncan
Seneca
Anderson

Browse thousands of different options on Cheapflights for your next trip

Toggle through the tabs below to find thousands of options on Cheapflights for your next trip.

Alternative routes for Portland to Greenville

See prices for flight routes from nearby airports that may be better suited for you.
Portland to Charlotte flights
Portland to Savannah flights
Boise to Charlotte flights
Portland to Charleston flights
Boise to Charleston flights
Portland to Myrtle Beach flights
Boise to Greenville flights
Portland to Columbia flights
Boise to Savannah flights
Eugene to Savannah flights
Boise to Myrtle Beach flights
Redmond to Charlotte flights
Eugene to Charlotte flights
Medford to Charlotte flights
Eugene to Greenville flights
Eugene to Charleston flights
Portland to Hilton Head Island flights
Redmond to Savannah flights
Medford to Greenville flights
Portland to Augusta flights
Redmond to Myrtle Beach flights
Eugene to Columbia flights
Portland to Florence flights
Yakima to Charleston flights
Eugene to Augusta flights
Medford to Columbia flights
Yakima to Charlotte flights
Pendleton to Charlotte flights
Redmond to Greenville flights
Yakima to Hilton Head Island flights

Top 5 airlines flying from Portland to Greenville

Discover the top 5 airlines that operate flights from Portland to Greenville. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated September 11, 2025.
AirlineCheapestAverageFlexibilityOn-time
DeltaCheapest$302Average$438FlexibilityNo cancel feeOn-timeN/A
United AirlinesCheapest$311Average$582FlexibilityNo cancel feeOn-time69%
American AirlinesCheapest$350Average$480FlexibilityNo cancel feeOn-time71%
SouthwestCheapest$367Average$552FlexibilityNo cancel feeOn-time63%
Alaska AirlinesCheapest$476Average$716FlexibilityNo cancel feeOn-time75%

100% Free

Cheapflights is completely free to use, so you can start saving the moment you arrive.

Book with Flexibility

Our users can plan ahead with confidence and find flights with no change fees

Travel Smart

Millions of people come to us for their flight needs every year. We help make travel planning easy by providing useful insights and data-driven graphs that can inform your decisions.