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$274+ Cheap flights from Portland, ME to Greenville (PWM - GSP)

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 12/23. Fares are subject to change and may not be available on all flights or dates of travel.
PWM — GSP
Nov 27 — Dec 41
Thu 11/27
Thu 12/4
1 adult, Economy
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Find flight deals from Portland to Greenville

Cheapest flights from Portland to Greenville
Explore the most affordable flight options available from Portland to Greenville. Find the lowest fares from popular airlines and budget airlines, with prices last updated on October 28, 2025.

This American Airlines deal was found by Cheapflights users on 10/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 12/45:46 amPWM - GSP
1 stop4h 21mAmerican Airlines
Tue 12/97:38 amGSP - PWM
1 stop3h 59mAmerican Airlines
Deal found 10/28$313
This Kiwi.com deal was found by Cheapflights users on 10/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 11/109:46 amPWM - GSP
1 stop9h 37mBreeze Airways
Fri 11/148:03 pmGSP - PWM
1 stop14h 33mBreeze Airways
Deal found 10/25$338
This American Airlines deal was found by Cheapflights users on 10/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 11/277:02 amPWM - GSP
1 stop5h 18mAmerican Airlines
Sat 12/610:38 amGSP - PWM
1 stop5h 47mAmerican Airlines
Deal found 10/26$343
This American Airlines deal was found by Cheapflights users on 10/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 11/115:43 amPWM - GSP
1 stop16h 48mAmerican Airlines
Sat 11/1510:33 amGSP - PWM
1 stop11h 14mAmerican Airlines
Deal found 10/27$387
This Southwest deal was found by Cheapflights users on 10/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 12/315:30 amPWM - GSP
1 stop4h 30mSouthwest
Sun 1/48:20 pmGSP - PWM
1 stop3h 45mSouthwest
Deal found 10/26$391
This Southwest deal was found by Cheapflights users on 10/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 12/2512:45 pmPWM - GSP
1 stop7h 05mSouthwest
Sun 12/288:20 pmGSP - PWM
1 stop3h 45mSouthwest
Deal found 10/27$427
This Breeze Airways deal was found by Cheapflights users on 10/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Breeze Airways is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 11/219:46 amPWM - GSP
1 stop9h 37mBreeze Airways
Sun 11/2310:33 amGSP - PWM
1 stop3h 57mBreeze Airways
Deal found 10/25$438

Cheap flight deals from Portland to Greenville

Discover tips and strategies to find the most affordable flight options for your journey from Portland (PWM) to Greenville (GSP). Learn about various techniques such as flexible date searches, comparing prices across and setting up price alerts. Use these methods to find the cheapest flights available for your travel needs. Data last updated October 28, 2025.

Most accurate provider

eDreams
3 stars

Most trusted provider

eDreams
3 stars

Round-trip from

$313
(American Airlines)

One-way from

$274
(Southwest)

Popular in

June

Cheapest in

September

Average price

$463
Provider with most accurate pricing for Portland-Greenville flight deals.
Search Deals
Provider most trusted by Cheapflights users for Portland-Greenville flights.
Search Deals
From Portland to Greenville
Search Deals
One-way flight from Portland to Greenville
Search Deals
Highest demand for flights based on searches. 6% potential increase in price ($29 potential increase over avg. RT price).
Search Deals
Cheapest flight prices on average. 3% potential price decrease ($12 potential savings vs. average RT price).
Search Deals
Average for round-trip flights in October 2025
Search Deals

Cheapflights Fare Finder

 
Customize your flight search to find flights from Portland to Greenville that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated October 28, 2025.
Use the filters below to find and compare flights from Portland to Greenville that are best for you.

Fly from

Portland

Fly to

Greenville

Route

Depart

Return

Price

PortlandGreenville

PWM - GSP

PWMGSP

Portland

Thu 12/4

6:00 am-10:34 am

1 stop4h 34m

Greenville

Tue 12/9

7:39 pm-11:37 pm

1 stop3h 58m

$313

PortlandGreenville

PWM - GSP

PWMGSP

Portland

Thu 11/27

7:02 am-12:20 pm

1 stop5h 18m

Greenville

Sat 12/6

10:38 am-4:25 pm

1 stop5h 47m

$343

PortlandGreenville

PWM - GSP

PWMGSP

Portland

Tue 3/31

5:00 pm-10:18 pm

1 stop5h 18m

Greenville

Wed 4/1

6:05 pm-11:05 pm

1 stop5h 00m

$387

PortlandGreenville

PWM - GSP

PWMGSP

Portland

Thu 1/1

5:30 am-10:00 am

1 stop4h 30m

Greenville

Sun 1/4

8:20 pm-12:05 am

1 stop3h 45m

$391

PortlandGreenville

PWM - GSP

PWMGSP

Portland

Wed 12/31

5:30 am-10:00 am

1 stop4h 30m

Greenville

Sun 1/4

8:20 pm-12:05 am

1 stop3h 45m

$391

PortlandGreenville

PWM - GSP

PWMGSP

Portland

Tue 12/23

5:30 pm-9:55 pm

1 stop4h 25m

$274

PortlandGreenville

PWM - GSP

PWMGSP

Portland

Tue 12/23

5:20 pm-11:58 pm

2 stops6h 38m

$395

PortlandGreenville

PWM - GSP

PWMGSP

Portland

Tue 12/23

11:58 am-3:50 pm

3 stops27h 52m

$453

Flights are sorted by cheapest round-trip flights first.

Deals found on 10/26

Compare providers for flights from Portland to Greenville

Provider information is updated monthly. Please note that these providers often have deals for this flight, but the availability may vary on a day-by-day basis on Cheapflights.
Use the table below to compare price accuracy, trust ratings, and cancellation policies for each provider offering flight deals from Portland to Greenville in October.
ProviderPrice AccuracyTrust Score*
ExpediaPrice Accuracy2 starsTrust Score*3 stars
FlightHubPrice Accuracy3 starsTrust Score*1 star
eDreamsPrice Accuracy3 starsTrust Score*3 stars

*The Trust Score is based on feedback from users after their booking experience. It measures overall satisfaction, helping us identify issues like hidden fees, problems during the ticketing process, and the quality of customer service. This score is our best indicator of the provider's quality and reliability.

  • Most accurate provider: When it comes to deals on Portland, Maine-Greenville flights, users find the pricing of eDreams to be most consistent on Cheapflights vs. eDreams Users can find the same prices on Portland, Maine-Greenville flight deals on Cheapflights vs. eDreams >95% of the time. Price accuracy is based on data collected from Portland, Maine-Greenville flight searches over the past month and is updated monthly.
  • Most trusted provider: When it comes to deals on Portland, Maine-Greenville flights, Cheapflights users trust eDreams the most. eDreams has received a user feedback score of 3 out of 3 stars (3 being the best), meaning they have been trusted the most by Cheapflights users looking for Portland, Maine-Greenville flight deals. Provider user feedback score is based on Cheapflights searches over the past month and is updated monthly.

Best time to book a flight from Portland to Greenville

Have a flexible travel schedule? Discover the best time to fly to Greenville from Portland with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Portland to Greenville

What is the cheapest month to book a flight from Portland, Maine to Greenville?

Currently, May is the cheapest month in which you can book a flight from Portland, Maine to Greenville (average of $54). Flying from Portland, Maine to Greenville in April is currently the most expensive (average of $115). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

Reviews of airlines servicing Greenville

Get insights into the airlines that provide service to Greenville. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Greenville. Reviews last updated October 28, 2025.
Peruse reviews from past customers who have flown with Southwest, Delta, and United Airlines from Portland to Greenville to help guide your decision. You can also see how each airline stacks up in terms of entertainment options, comfort, food, crew/service, and boarding process.
Southwest
8.0
Very good
4,240 reviews

Crew

8.6

Boarding

8.1

Overall

8.0

Comfort

8.0

Food

7.0

Entertainment

7.5

Reviews

1 / 20
2.0
Mediocre

Mike,Aug 2025

OKC - AUS

AC was not adequate, even on a night flight. WiFi subpar even for the airlines
Southwest
8.0
Very good
4,240 reviews
Southwest
8.0
Very good
4,240 reviews

Crew

8.6

Boarding

8.1

Overall

8.0

Comfort

8.0

Food

7.0

Entertainment

7.5

Reviews

1 / 20
2.0
Mediocre

Mike,Aug 2025

OKC - AUS

AC was not adequate, even on a night flight. WiFi subpar even for the airlines
Delta
7.9
Good
7,994 reviews
Southwest
8.0
Very good
4,240 reviews

Crew

8.6

Boarding

8.1

Overall

8.0

Comfort

8.0

Food

7.0

Entertainment

7.5

Reviews

1 / 20
2.0
Mediocre

Mike,Aug 2025

OKC - AUS

AC was not adequate, even on a night flight. WiFi subpar even for the airlines
United Airlines
7.4
Good
9,001 reviews
Southwest
8.0
Very good
4,240 reviews

Crew

8.6

Boarding

8.1

Overall

8.0

Comfort

8.0

Food

7.0

Entertainment

7.5

Reviews

1 / 20
2.0
Mediocre

Mike,Aug 2025

OKC - AUS

AC was not adequate, even on a night flight. WiFi subpar even for the airlines
American Airlines
7.2
Good
11,032 reviews
Southwest
8.0
Very good
4,240 reviews

Crew

8.6

Boarding

8.1

Overall

8.0

Comfort

8.0

Food

7.0

Entertainment

7.5

Reviews

1 / 20
2.0
Mediocre

Mike,Aug 2025

OKC - AUS

AC was not adequate, even on a night flight. WiFi subpar even for the airlines

Related info for your journey

Find useful and relevant information for your journey from Portland to Greenville. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • How long is the flight from Portland, Maine to Greenville?

    There are many flights that can get you from Portland, Maine to Greenville in 4h 34m. Fly via American Airlines to get the fastest option. The distance between Portland, Maine and Greenville is about 876 mi.

  • What are the cheapest airlines flying from Portland, Maine to Greenville round-trip?

    Currently priced at $258, American Airlines will fly you from Portland, Maine to Greenville and back. In addition to American Airlines, many other airlines offer competitively priced options for your trip. Search Cheapflights for deals from Delta and United Airlines - these airlines can fly you to your destination from $270 and $296, respectively. American Airlines is priced at 36% lower than the current average price of a flight leaving 3 months from now.

  • Can I find deals for flights from Portland to Greenville that include hotel bookings?

    Yes. In addition to deals on Portland to Greenville flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Portland to Greenville?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Portland to Greenville.

  • Can I find deals for business class flights from Portland to Greenville?

    Yes. Cheapflights offers flight deals from Portland to Greenville by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Portland, Maine to Greenville?

    Currently, May is the cheapest month in which you can book a flight from Portland, Maine to Greenville (average of $54). Flying from Portland, Maine to Greenville in April is currently the most expensive (average of $115). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

Traveling to a place near Greenville?

Book flights to Greenville if you plan to visit one of these locations
Simpsonville
Duncan
Greer
Seneca
Anderson

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Top 4 airlines flying from Portland to Greenville

Discover the top 4 airlines that operate flights from Portland to Greenville. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated October 28, 2025.
AirlineCheapestAverageFlexibilityOn-time
American AirlinesCheapest$258Average$402FlexibilityNo cancel feeOn-time71%
DeltaCheapest$270Average$380FlexibilityNo cancel feeOn-timeN/A
United AirlinesCheapest$296Average$386FlexibilityNo cancel feeOn-time69%
SouthwestCheapest$336Average$428FlexibilityNo cancel feeOn-time63%

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