HomeSearch by dateVacation packagesHotelsFlight dealsCar rentalTravel tips & news
Greenville

$150+ Cheap flights from Portland, ME to Greenville (PWM - GSP)

This is the cheapest round-trip flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 9/11. Fares are subject to change and may not be available on all flights or dates of travel.
PWM — GSP
ago. 3 — ago. 101
dom. 8/3
dom. 8/10
1 adult, Economy
We work with more than 300 partners to bring you better travel deals

Find cheap flights from Portland to Greenville with Cheapflights

1. Tell us where you want to go

Enter your travel information like dates, passengers, trip type (one-way or round trip), and preferred cabin class then click “Find deals”

2. Select your favorite providers

We find the providers serving your travel needs. Choose up to four travel providers to compare side-by-side for flights, hotels, or car rentals.

3. Compare prices and book

Review each provider’s pricing and select the best option for you! Book through your favorite provider’s website for a seamless experience.

Cheap flight deals from Portland to Greenville

Discover tips and strategies to find the most affordable flight options for your journey from Portland (PWM) to Greenville (GSP). Learn about various techniques such as flexible date searches, comparing prices across and setting up price alerts. Use these methods to find the cheapest flights available for your travel needs. Data last updated julio 29, 2025.

Round-trip from

$150
(Kiwi.com)

Popular in

June

Cheapest in

September

Average price

$366
From Portland to Greenville
Search Deals
Highest demand for flights based on searches. 9% potential increase in price ($40 potential increase over avg. RT price).
Search Deals
Cheapest flight prices on average. 3% potential price decrease ($12 potential savings vs. average RT price).
Search Deals
Average for round-trip flights in July 2025
Search Deals

Find flight deals from Portland to Greenville

Cheapest flights from Portland to Greenville
Explore the most affordable flight options available from Portland to Greenville. Find the lowest fares from popular airlines and budget airlines, with prices last updated on julio 29, 2025.

This Kiwi.com deal was found by Cheapflights users on 7/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
jue. 9/113:15 pmPWM - GSP
1 stop4h 08mBreeze Airways
dom. 9/1410:33 amGSP - PWM
1 stop3h 57mBreeze Airways
Deal found 7/29$150
This Delta deal was found by Cheapflights users on 7/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
jue. 9/116:00 amPWM - GSP
2 stops9h 23mDelta
dom. 9/146:00 amGSP - PWM
1 stop7h 00mDelta
Deal found 7/29$242
This American Airlines deal was found by Cheapflights users on 7/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
mar. 8/196:00 amPWM - GSP
1 stop4h 52mAmerican Airlines
lun. 8/2510:44 amGSP - PWM
1 stop10h 59mAmerican Airlines
Deal found 7/27$296
This Southwest deal was found by Cheapflights users on 7/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
mar. 11/43:30 pmPWM - GSP
1 stop4h 20mSouthwest
dom. 11/98:00 amGSP - PWM
1 stop6h 25mSouthwest
Deal found 7/28$332
This United Airlines deal was found by Cheapflights users on 7/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
lun. 9/152:14 pmPWM - GSP
2 stops8h 46mUnited Airlines
lun. 9/226:08 amGSP - PWM
1 stop7h 14mUnited Airlines
Deal found 7/28$458

Cheapflights Fare Finder

 
Customize your flight search to find flights from Portland to Greenville that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated julio 29, 2025.
Use the filters below to find and compare flights from Portland to Greenville that are best for you.

Fly from

Portland

Fly to

Greenville

Route

Depart

Return

Price

PortlandGreenville

PWM - GSP

PWMGSP

Portland

jue. 9/11

3:15 pm-7:23 pm

1 stop4h 08m

Greenville

dom. 9/14

10:33 am-2:30 pm

1 stop3h 57m

$150

PortlandGreenville

PWM - GSP

PWMGSP

Portland

jue. 9/11

6:00 am-3:23 pm

2 stops9h 23m

Greenville

dom. 9/14

6:00 am-1:00 pm

1 stop7h 00m

$242

PortlandGreenville

PWM - GSP

PWMGSP

Portland

mar. 8/19

6:00 am-10:52 am

1 stop4h 52m

Greenville

lun. 8/25

10:44 am-9:43 pm

1 stop10h 59m

$296

PortlandGreenville

PWM - GSP

PWMGSP

Portland

mar. 11/4

3:30 pm-7:50 pm

1 stop4h 20m

Greenville

dom. 11/9

8:00 am-2:25 pm

1 stop6h 25m

$332

PortlandGreenville

PWM - GSP

PWMGSP

Portland

lun. 9/15

2:14 pm-11:00 pm

2 stops8h 46m

Greenville

lun. 9/22

6:08 am-1:22 pm

1 stop7h 14m

$458

PortlandGreenville

PWM - GSP

PWMGSP

Portland

lun. 10/20

4:15 pm-8:43 pm

1 stop4h 28m

$154

PortlandGreenville

PWM - GSP

PWMGSP

Portland

dom. 9/7

5:35 am-7:15 pm

2 stops13h 40m

$224

PortlandGreenville

PWM - GSP

PWMGSP

Portland

lun. 10/20

4:48 pm-11:54 pm

2 stops7h 06m

$365

PortlandGreenville

PWM - GSP

PWMGSP

Portland

dom. 10/5

5:45 am-11:15 pm

2 stops17h 30m

$533

PortlandGreenville

PWM - GSP

PWMGSP

Portland

dom. 9/7

3:15 pm-6:46 pm

3 stops27h 31m

$592

Flights are sorted by cheapest round-trip flights first.

Deals found on 7/28

Best time to book a flight from Portland to Greenville

Have a flexible travel schedule? Discover the best time to fly to Greenville from Portland with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Portland to Greenville

What is the cheapest month to book a flight from Portland, Maine to Greenville?

Currently, January is the cheapest month in which you can book a flight from Portland, Maine to Greenville (average of $329). Flying from Portland, Maine to Greenville in March is currently the most expensive (average of $386). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

Reviews of airlines servicing Greenville

Get insights into the airlines that provide service to Greenville. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Greenville. Reviews last updated julio 29, 2025.
Peruse reviews from past customers who have flown with Southwest, Delta, and Breeze Airways from Portland to Greenville to help guide your decision. You can also see how each airline stacks up in terms of entertainment options, comfort, food, crew/service, and boarding process.
Southwest
8.0
Very good
4,238 reviews

Comfort

8.0

Boarding

8.1

Overall

8.0

Entertainment

7.5

Food

7.0

Crew

8.6

Reviews

1 / 20
8.0
Excellent

Gina,Jul 2025

LAS - DEN

We experienced bad weather, which turned our 1.5 hour flight from Las Vegas to Denver, into 3.5. The pilot and crew kept us updated and explained that we had to circle and or possibly redirect to another airport. After circling for sometime, we were able to land smoothly in Denver. Thank you to all the flight crew, tower control, and all who got us to our destination safely.
Southwest
8.0
Very good
4,238 reviews
Southwest
8.0
Very good
4,238 reviews

Comfort

8.0

Boarding

8.1

Overall

8.0

Entertainment

7.5

Food

7.0

Crew

8.6

Reviews

1 / 20
8.0
Excellent

Gina,Jul 2025

LAS - DEN

We experienced bad weather, which turned our 1.5 hour flight from Las Vegas to Denver, into 3.5. The pilot and crew kept us updated and explained that we had to circle and or possibly redirect to another airport. After circling for sometime, we were able to land smoothly in Denver. Thank you to all the flight crew, tower control, and all who got us to our destination safely.
Delta
8.0
Very good
7,979 reviews
Southwest
8.0
Very good
4,238 reviews

Comfort

8.0

Boarding

8.1

Overall

8.0

Entertainment

7.5

Food

7.0

Crew

8.6

Reviews

1 / 20
8.0
Excellent

Gina,Jul 2025

LAS - DEN

We experienced bad weather, which turned our 1.5 hour flight from Las Vegas to Denver, into 3.5. The pilot and crew kept us updated and explained that we had to circle and or possibly redirect to another airport. After circling for sometime, we were able to land smoothly in Denver. Thank you to all the flight crew, tower control, and all who got us to our destination safely.
Breeze Airways
8.0
Very good
190 reviews
Southwest
8.0
Very good
4,238 reviews

Comfort

8.0

Boarding

8.1

Overall

8.0

Entertainment

7.5

Food

7.0

Crew

8.6

Reviews

1 / 20
8.0
Excellent

Gina,Jul 2025

LAS - DEN

We experienced bad weather, which turned our 1.5 hour flight from Las Vegas to Denver, into 3.5. The pilot and crew kept us updated and explained that we had to circle and or possibly redirect to another airport. After circling for sometime, we were able to land smoothly in Denver. Thank you to all the flight crew, tower control, and all who got us to our destination safely.
United Airlines
7.4
Good
8,896 reviews
Southwest
8.0
Very good
4,238 reviews

Comfort

8.0

Boarding

8.1

Overall

8.0

Entertainment

7.5

Food

7.0

Crew

8.6

Reviews

1 / 20
8.0
Excellent

Gina,Jul 2025

LAS - DEN

We experienced bad weather, which turned our 1.5 hour flight from Las Vegas to Denver, into 3.5. The pilot and crew kept us updated and explained that we had to circle and or possibly redirect to another airport. After circling for sometime, we were able to land smoothly in Denver. Thank you to all the flight crew, tower control, and all who got us to our destination safely.
American Airlines
7.2
Good
10,000 reviews
Southwest
8.0
Very good
4,238 reviews

Comfort

8.0

Boarding

8.1

Overall

8.0

Entertainment

7.5

Food

7.0

Crew

8.6

Reviews

1 / 20
8.0
Excellent

Gina,Jul 2025

LAS - DEN

We experienced bad weather, which turned our 1.5 hour flight from Las Vegas to Denver, into 3.5. The pilot and crew kept us updated and explained that we had to circle and or possibly redirect to another airport. After circling for sometime, we were able to land smoothly in Denver. Thank you to all the flight crew, tower control, and all who got us to our destination safely.

Related info for your journey

Find useful and relevant information for your journey from Portland to Greenville. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • What are the cheapest airlines flying from Portland, Maine to Greenville round-trip?

    Currently priced at $150, Breeze Airways will fly you from Portland, Maine to Greenville and back. In addition to Breeze Airways, many other airlines offer competitively priced options for your trip. Search Cheapflights for deals from Delta and American Airlines - these airlines can fly you to your destination from $242 and $296, respectively. Breeze Airways is priced at 62% lower than the current average price of a flight leaving 3 months from now.

  • What are the cheapest airlines to fly from Portland, Maine to Greenville one-way?

    $154 is the cheapest one-way deal found within the past few days, from American Airlines. You may also be able to find cheap deals on Southwest and Delta, with prices starting from $224 and $365, respectively.

  • Can I find deals for flights from Portland to Greenville that include hotel bookings?

    Yes. In addition to deals on Portland to Greenville flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Portland to Greenville?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Portland to Greenville.

  • Can I find deals for business class flights from Portland to Greenville?

    Yes. Cheapflights offers flight deals from Portland to Greenville by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Portland, Maine to Greenville?

    Currently, January is the cheapest month in which you can book a flight from Portland, Maine to Greenville (average of $329). Flying from Portland, Maine to Greenville in March is currently the most expensive (average of $386). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

Traveling to a place near Greenville?

Book flights to Greenville if you plan to visit one of these locations
Simpsonville
Duncan
Seneca
Anderson

Browse thousands of different options on Cheapflights for your next trip

Toggle through the tabs below to find thousands of options on Cheapflights for your next trip.

Alternative routes for Portland to Greenville

See prices for flight routes from nearby airports that may be better suited for you.
Boston to Charleston flights
Boston to Charlotte flights
Boston to Myrtle Beach flights
Boston to Savannah flights
Boston to Columbia flights
Portland to Charlotte flights
Boston to Greenville flights
Portland to Charleston flights
Boston to Hilton Head Island flights
Portland to Savannah flights
Bangor to Charlotte flights
Boston to Augusta flights
Portland to Myrtle Beach flights
Bangor to Savannah flights
Bangor to Charleston flights
Bangor to Greenville flights
Bangor to Myrtle Beach flights
Portland to Hilton Head Island flights
Boston to Florence flights
Portland to Augusta flights
Portland to Columbia flights
Augusta to Charleston flights
Portland to Florence flights
Rockland to Charlotte flights
Rockland to Charleston flights
Augusta to Charlotte flights

Top 3 airlines flying from Portland to Greenville

Discover the top 3 airlines that operate flights from Portland to Greenville. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated julio 29, 2025.
AirlineCheapestAverageFlexibilityOn-time
DeltaCheapest$270Average$380FlexibilityNo cancel feeOn-timeN/A
American AirlinesCheapest$275Average$406FlexibilityNo cancel feeOn-time71%
SouthwestCheapest$301Average$416FlexibilityNo cancel feeOn-time63%

100% Free

Cheapflights is completely free to use, so you can start saving the moment you arrive.

Book with Flexibility

Our users can plan ahead with confidence and find flights with no change fees

Travel Smart

Millions of people come to us for their flight needs every year. We help make travel planning easy by providing useful insights and data-driven graphs that can inform your decisions.