HomeSearch by dateVacation packagesHotelsFlight dealsCar rentalTravel tips & news
Greenville

$171+ Cheap flights from Portland, ME to Greenville (PWM - GSP)

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 1/15. Fares are subject to change and may not be available on all flights or dates of travel.
PWM — GSP
ene. 11 — ene. 181
dom. 1/11
dom. 1/18
1 adult, Economy
We work with more than 300 partners to bring you better travel deals

Find cheap flights from Portland to Greenville with Cheapflights

1. Tell us where you want to go

Enter your travel information like dates, passengers, trip type (one-way or round trip), and preferred cabin class then click “Find deals”

2. Select your favorite providers

We find the providers serving your travel needs. Choose up to four travel providers to compare side-by-side for flights, hotels, or car rentals.

3. Compare prices and book

Review each provider’s pricing and select the best option for you! Book through your favorite provider’s website for a seamless experience.

Cheap flight deals from Portland to Greenville

Cheapest flights from Portland to Greenville
Explore the most affordable flight options available from Portland to Greenville. Find the lowest fares from popular airlines and budget airlines, with prices last updated on diciembre 12, 2025.

This Kiwi.com deal was found by Cheapflights users on 12/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
lun. 12/159:46 amPWM - GSP
1 stop9h 37mMultiple Airlines
mié. 12/314:45 pmGSP - PWM
2 stops48h 40mMultiple Airlines
Deal found 12/11$372
This American Airlines deal was found by Cheapflights users on 12/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
mié. 12/315:48 amPWM - GSP
1 stop4h 25mAmerican Airlines
dom. 1/45:39 amGSP - PWM
1 stop6h 32mAmerican Airlines
Deal found 12/10$432
This American Airlines deal was found by Cheapflights users on 12/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
jue. 12/2512:21 pmPWM - GSP
1 stop6h 18mAmerican Airlines
lun. 12/297:37 amGSP - PWM
1 stop4h 12mAmerican Airlines
Deal found 12/10$540
This Kiwi.com deal was found by Cheapflights users on 12/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
mié. 12/3111:16 amPWM - GSP
1 stop23h 37mMultiple Airlines
dom. 1/411:33 amGSP - PWM
2 stops23h 08mMultiple Airlines
Deal found 12/10$543
This United Airlines deal was found by Cheapflights users on 12/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
vie. 12/196:46 pmPWM - GSP
1 stop5h 10mUnited Airlines
dom. 12/219:40 amGSP - PWM
1 stop14h 19mUnited Airlines
Deal found 12/10$682
This United Airlines deal was found by Cheapflights users on 12/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
lun. 12/154:25 pmPWM - GSP
1 stop19h 19mUnited Airlines
mié. 12/319:40 amGSP - PWM
1 stop14h 19mUnited Airlines
Deal found 12/11$719

Find flight deals from Portland to Greenville

Discover tips and strategies to find the most affordable flight options for your journey from Portland (PWM) to Greenville (GSP). Learn about various techniques such as flexible date searches, comparing prices across and setting up price alerts. Use these methods to find the cheapest flights available for your travel needs. Data last updated diciembre 12, 2025.

Most accurate provider

eDreams
3 stars

Most trusted provider

eDreams
3 stars

Round-trip from

$269
(Delta)

One-way from

$171
(Delta)

Popular in

November

Cheapest in

September

Average price

$411
Provider with most accurate pricing for Portland-Greenville flight deals.
Search Deals
Provider most trusted by Cheapflights users for Portland-Greenville flights.
Search Deals
From Portland to Greenville
Search Deals
One-way flight from Portland to Greenville
Search Deals
Highest demand for flights based on searches. 17% potential increase in price ($87 potential increase over avg. RT price).
Search Deals
Cheapest flight prices on average. 5% potential price decrease ($24 potential savings vs. average RT price).
Search Deals
Average for round-trip flights in December 2025
Search Deals

Cheapflights Fare Finder

 
Customize your flight search to find flights from Portland to Greenville that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated diciembre 12, 2025.
Use the filters below to find and compare flights from Portland to Greenville that are best for you.

Fly from

Portland

Fly to

Greenville

Route

Depart

Return

Price

PortlandGreenville

PWM - GSP

PWMGSP

Portland

sáb. 1/17

1:13 pm-10:24 pm

2 stops9h 11m

Greenville

mar. 1/20

5:26 pm-12:20 am

2 stops6h 54m

$279

PortlandGreenville

PWM - GSP

PWMGSP

Portland

jue. 1/1

6:46 pm-11:56 pm

1 stop5h 10m

Greenville

jue. 1/8

6:35 am-2:39 pm

1 stop8h 04m

$305

PortlandGreenville

PWM - GSP

PWMGSP

Portland

vie. 1/9

12:46 pm-10:16 pm

1 stop9h 30m

Greenville

vie. 1/16

7:42 pm-12:06 pm

1 stop16h 24m

$367

PortlandGreenville

PWM - GSP

PWMGSP

Portland

jue. 1/8

2:31 pm-7:29 pm

1 stop4h 58m

Greenville

lun. 1/12

6:35 am-2:39 pm

1 stop8h 04m

$411

PortlandGreenville

PWM - GSP

PWMGSP

Portland

jue. 1/15

6:00 am-11:08 am

1 stop5h 08m

$171

PortlandGreenville

PWM - GSP

PWMGSP

Portland

jue. 1/8

6:00 am-10:50 am

1 stop4h 50m

$171

PortlandGreenville

PWM - GSP

PWMGSP

Portland

jue. 1/15

5:57 pm-10:44 pm

1 stop4h 47m

$171

PortlandGreenville

PWM - GSP

PWMGSP

Portland

jue. 1/15

5:20 am-3:14 pm

2 stops9h 54m

$176

PortlandGreenville

PWM - GSP

PWMGSP

Portland

mié. 12/17

11:16 am-3:15 pm

1 stop27h 59m

$214

PortlandGreenville

PWM - GSP

PWMGSP

Portland

vie. 12/19

9:46 am-7:23 pm

1 stop9h 37m

$223

Flights are sorted by cheapest round-trip flights first.

Deals found on 12/10

Showing 1-10 of 14 results
1
2

Compare providers for flights from Portland to Greenville

Provider information is updated monthly. Please note that these providers often have deals for this flight, but the availability may vary on a day-by-day basis on Cheapflights.
Use the table below to compare price accuracy, trust ratings, and cancellation policies for each provider offering flight deals from Portland to Greenville in December.
ProviderPrice AccuracyTrust Score*
ExpediaPrice Accuracy2 starsTrust Score*3 stars
FlightHubPrice Accuracy3 starsTrust Score*1 star
eDreamsPrice Accuracy3 starsTrust Score*3 stars

*The Trust Score is based on feedback from users after their booking experience. It measures overall satisfaction, helping us identify issues like hidden fees, problems during the ticketing process, and the quality of customer service. This score is our best indicator of the provider's quality and reliability.

  • Most accurate provider: When it comes to deals on Portland, Maine-Greenville flights, users find the pricing of eDreams to be most consistent on Cheapflights vs. eDreams Users can find the same prices on Portland, Maine-Greenville flight deals on Cheapflights vs. eDreams >95% of the time. Price accuracy is based on data collected from Portland, Maine-Greenville flight searches over the past month and is updated monthly.
  • Most trusted provider: When it comes to deals on Portland, Maine-Greenville flights, Cheapflights users trust eDreams the most. eDreams has received a user feedback score of 3 out of 3 stars (3 being the best), meaning they have been trusted the most by Cheapflights users looking for Portland, Maine-Greenville flight deals. Provider user feedback score is based on Cheapflights searches over the past month and is updated monthly.

Best time to book a flight from Portland to Greenville

Have a flexible travel schedule? Discover the best time to fly to Greenville from Portland with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Portland to Greenville

What is the cheapest month to book a flight from Portland, Maine to Greenville?

Currently, May is the cheapest month in which you can book a flight from Portland, Maine to Greenville (average of $54). Flying from Portland, Maine to Greenville in November is currently the most expensive (average of $132). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

Reviews of airlines servicing Greenville

Get insights into the airlines that provide service to Greenville. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Greenville. Reviews last updated diciembre 12, 2025.
Peruse reviews from past customers who have flown with Southwest, Delta, and United Airlines from Portland to Greenville to help guide your decision. You can also see how each airline stacks up in terms of entertainment options, comfort, food, crew/service, and boarding process.
Southwest
7.9
Good
4,253 reviews

Food

7.0

Comfort

8.0

Crew

8.6

Entertainment

7.5

Overall

7.9

Boarding

8.1

Reviews

1 / 20
2.0
Mediocre

Thomas,Dec 2025

SEA - DEN

Plane two hours late in leaving 1:00 pm west coat time got home next day at 2:45am most car rental places are closed and don’t open till 5am
Southwest
7.9
Good
4,253 reviews
Southwest
7.9
Good
4,253 reviews

Food

7.0

Comfort

8.0

Crew

8.6

Entertainment

7.5

Overall

7.9

Boarding

8.1

Reviews

1 / 20
2.0
Mediocre

Thomas,Dec 2025

SEA - DEN

Plane two hours late in leaving 1:00 pm west coat time got home next day at 2:45am most car rental places are closed and don’t open till 5am
Delta
7.9
Good
8,008 reviews
Southwest
7.9
Good
4,253 reviews

Food

7.0

Comfort

8.0

Crew

8.6

Entertainment

7.5

Overall

7.9

Boarding

8.1

Reviews

1 / 20
2.0
Mediocre

Thomas,Dec 2025

SEA - DEN

Plane two hours late in leaving 1:00 pm west coat time got home next day at 2:45am most car rental places are closed and don’t open till 5am
United Airlines
7.4
Good
9,095 reviews
Southwest
7.9
Good
4,253 reviews

Food

7.0

Comfort

8.0

Crew

8.6

Entertainment

7.5

Overall

7.9

Boarding

8.1

Reviews

1 / 20
2.0
Mediocre

Thomas,Dec 2025

SEA - DEN

Plane two hours late in leaving 1:00 pm west coat time got home next day at 2:45am most car rental places are closed and don’t open till 5am
American Airlines
7.2
Good
11,050 reviews
Southwest
7.9
Good
4,253 reviews

Food

7.0

Comfort

8.0

Crew

8.6

Entertainment

7.5

Overall

7.9

Boarding

8.1

Reviews

1 / 20
2.0
Mediocre

Thomas,Dec 2025

SEA - DEN

Plane two hours late in leaving 1:00 pm west coat time got home next day at 2:45am most car rental places are closed and don’t open till 5am

Related info for your journey

Find useful and relevant information for your journey from Portland to Greenville. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • How long is the flight from Portland, Maine to Greenville?

    There are many flights that can get you from Portland, Maine to Greenville in 5h 10m. Fly via Delta, United Airlines, or American Airlines to get the fastest option. The distance between Portland, Maine and Greenville is about 876 mi. This flight may include one or multiple stops.

  • What are the cheapest airlines flying from Portland, Maine to Greenville round-trip?

    Currently priced at $213, Delta will fly you from Portland, Maine to Greenville and back. In addition to Delta, many other airlines offer competitively priced options for your trip. Search Cheapflights for deals from American Airlines and United Airlines - these airlines can fly you to your destination from $258 and $296, respectively. Delta is priced at 48% lower than the current average price of a flight leaving 3 months from now.

  • What are the cheapest airlines to fly from Portland, Maine to Greenville one-way?

    $94 is the cheapest one-way deal found within the past few days, from Breeze Airways. You may also be able to find cheap deals on American Airlines and Delta, with prices starting from $118 and $148, respectively.

  • Can I find deals for flights from Portland to Greenville that include hotel bookings?

    Yes. In addition to deals on Portland to Greenville flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Portland to Greenville?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Portland to Greenville.

  • Can I find deals for business class flights from Portland to Greenville?

    Yes. Cheapflights offers flight deals from Portland to Greenville by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Portland, Maine to Greenville?

    Currently, May is the cheapest month in which you can book a flight from Portland, Maine to Greenville (average of $54). Flying from Portland, Maine to Greenville in November is currently the most expensive (average of $132). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

Traveling to a place near Greenville?

Book flights to Greenville if you plan to visit one of these locations
Simpsonville
Duncan
Greer
Seneca
Anderson

Browse thousands of different options on Cheapflights for your next trip

Toggle through the tabs below to find thousands of options on Cheapflights for your next trip.

Alternative routes for Portland to Greenville

See prices for flight routes from nearby airports that may be better suited for you.
Boston to Charlotte flights
Boston to Charleston flights
Boston to Savannah flights
Boston to Myrtle Beach flights
Portland to Charleston flights
Portland to Charlotte flights
Boston to Hilton Head Island flights
Boston to Greenville flights
Boston to Columbia flights
Portland to Myrtle Beach flights
Boston to Augusta flights
Portland to Savannah flights
Bangor to Charlotte flights
Bangor to Savannah flights
Portland to Columbia flights
Portland to Hilton Head Island flights
Boston to Florence flights
Bangor to Charleston flights
Bangor to Greenville flights
Portland to Augusta flights
Bangor to Myrtle Beach flights
Augusta to Charleston flights
Augusta to Charlotte flights
Portland to Florence flights
Rockland to Charleston flights
Rockland to Charlotte flights

Top 4 airlines flying from Portland to Greenville

Discover the top 4 airlines that operate flights from Portland to Greenville. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated diciembre 12, 2025.
AirlineCheapestAverageFlexibilityOn-time
American AirlinesCheapest$258Average$386FlexibilityNo cancel feeOn-time71%
DeltaCheapest$270Average$380FlexibilityNo cancel feeOn-timeN/A
United AirlinesCheapest$296Average$386FlexibilityNo cancel feeOn-time69%
SouthwestCheapest$316Average$416FlexibilityNo cancel feeOn-time63%

100% Free

Cheapflights is completely free to use, so you can start saving the moment you arrive.

Book with Flexibility

Our users can plan ahead with confidence and find flights with no change fees

Travel Smart

Millions of people come to us for their flight needs every year. We help make travel planning easy by providing useful insights and data-driven graphs that can inform your decisions.