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$90+ Cheap flights from Detroit Metropolitan Wayne County Airport to Greenville (DTW - GSP)

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 1/25. Fares are subject to change and may not be available on all flights or dates of travel.
DTW — GSP
Nov 28 — Dec 51
Fri 11/28
Fri 12/5
1 adult, Economy
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Find cheap flights from Detroit to Greenville with Cheapflights

1. Tell us where you want to go

Enter your travel information like dates, passengers, trip type (one-way or round trip), and preferred cabin class then click “Find deals”

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Cheapflights Tip: The best prices from Detroit Metropolitan Wayne County to Greenville are usually found in February or September, booked 80 days in advance, depart on a Thursday or Friday and return on a Saturday

Find flight deals from Detroit to Greenville

Cheapest flights from Detroit to Greenville
Explore the most affordable flight options available from Detroit to Greenville. Find the lowest fares from popular airlines and budget airlines, with prices last updated on October 29, 2025.

This Kiwi.com deal was found by Cheapflights users on 10/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 12/56:45 amDTW - GSP
1 stop14h 04mMultiple Airlines
Sun 12/74:00 pmGSP - DTW
1 stop16h 20mMultiple Airlines
Deal found 10/27$231
This Kiwi.com deal was found by Cheapflights users on 10/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 11/136:55 pmDTW - GSP
2 stops24h 28mMultiple Airlines
Mon 11/178:03 pmGSP - DTW
1 stop13h 55mMultiple Airlines
Deal found 10/28$238
This Kiwi.com deal was found by Cheapflights users on 10/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 12/134:20 pmDTW - GSP
1 stop16h 33mMultiple Airlines
Sat 12/209:41 pmGSP - DTW
1 stop11h 52mMultiple Airlines
Deal found 10/28$258
This Kiwi.com deal was found by Cheapflights users on 10/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 12/46:00 amDTW - GSP
1 stop9h 10mMultiple Airlines
Sun 12/74:00 pmGSP - DTW
1 stop16h 20mMultiple Airlines
Deal found 10/27$287
This Kiwi.com deal was found by Cheapflights users on 10/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 11/312:24 pmDTW - GSP
1 stop6h 59mMultiple Airlines
Fri 11/78:03 pmGSP - DTW
1 stop14h 44mMultiple Airlines
Deal found 10/27$293
This Kiwi.com deal was found by Cheapflights users on 10/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 11/187:17 pmDTW - GSP
2 stops20h 09mMultiple Airlines
Thu 11/205:17 pmGSP - DTW
1 stop6h 16mMultiple Airlines
Deal found 10/28$298
This Kiwi.com deal was found by Cheapflights users on 10/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 11/910:31 amDTW - GSP
1 stop10h 43mMultiple Airlines
Mon 11/108:03 pmGSP - DTW
1 stop13h 55mMultiple Airlines
Deal found 10/26$320
This American Airlines deal was found by Cheapflights users on 10/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 12/1311:34 amDTW - GSP
1 stop10h 11mAmerican Airlines
Tue 1/137:50 amGSP - DTW
1 stop9h 37mAmerican Airlines
Deal found 10/28$325

Cheap flight deals from Detroit to Greenville

Discover tips and strategies to find the most affordable flight options for your journey from Detroit (DTW) to Greenville (GSP). Learn about various techniques such as flexible date searches, comparing prices across and setting up price alerts. Use these methods to find the cheapest flights available for your travel needs. Data last updated October 29, 2025.

Most accurate provider

eDreams
3 stars

Most trusted provider

eDreams
3 stars

Round-trip from

$231
(Kiwi.com)

One-way from

$90
(Kiwi.com)

Popular in

October

Cheapest in

February

Average price

$609

Good round-trip deal

$399 or less

Good one-way deal

$333 or less
Provider with most accurate pricing for Detroit Metropolitan Wayne County-Greenville flight deals.
Search Deals
Provider most trusted by Cheapflights users for Detroit Metropolitan Wayne County-Greenville flights.
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From Detroit Metropolitan Wayne County to Greenville
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One-way flight from Detroit Metropolitan Wayne County to Greenville
Search Deals
Highest demand for flights based on searches. 9% potential increase in price ($48 potential increase over avg. RT price).
Search Deals
Cheapest flight prices on average. 2% potential price decrease ($13 potential savings vs. average RT price).
Search Deals
Average for round-trip flights in October 2025
Search Deals
Price to beat on a round-trip flight from Detroit Metropolitan Wayne County to Greenville.
Search Deals
Price to beat on a one-way flight from Detroit Metropolitan Wayne County to Greenville.
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Cheapflights Fare Finder

 
Customize your flight search to find flights from Detroit to Greenville that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated October 29, 2025.
Use the filters below to find and compare flights from Detroit Metropolitan Wayne County Airport to Greenville that are best for you.

Fly from

Detroit

Fly to

Greenville

Route

Depart

Return

Price

DetroitGreenville

DTW - GSP

DTWGSP

Detroit Metropolitan Wayne County

Thu 11/13

6:55 pm-7:23 pm

2 stops24h 28m

Greenville

Mon 11/17

8:03 pm-9:58 am

1 stop13h 55m

$238

DetroitGreenville

DTW - GSP

DTWGSP

Detroit Metropolitan Wayne County

Sat 12/13

4:20 pm-8:53 am

1 stop16h 33m

Greenville

Sat 12/20

9:41 pm-9:33 am

1 stop11h 52m

$258

DetroitGreenville

DTW - GSP

DTWGSP

Detroit Metropolitan Wayne County

Fri 12/12

2:10 pm-10:29 pm

1 stop8h 19m

Greenville

Tue 1/13

12:37 pm-10:45 pm

1 stop10h 08m

$341

DetroitGreenville

DTW - GSP

DTWGSP

Detroit Metropolitan Wayne County

Wed 11/12

11:57 am-10:15 pm

1 stop10h 18m

Greenville

Sat 11/15

7:47 am-6:15 pm

1 stop10h 28m

$395

DetroitGreenville

DTW - GSP

DTWGSP

Detroit Metropolitan Wayne County

Fri 12/19

11:05 am-7:23 pm

1 stop8h 18m

Greenville

Mon 12/22

8:43 pm-9:56 pm

1 stop25h 13m

$396

DetroitGreenville

DTW - GSP

DTWGSP

Detroit Metropolitan Wayne County

Mon 12/22

6:15 am-9:14 pm

1 stop14h 59m

Greenville

Sat 12/27

3:30 pm-8:51 am

1 stop17h 21m

$398

DetroitGreenville

DTW - GSP

DTWGSP

Detroit Metropolitan Wayne County

Sat 12/13

4:10 pm-5:50 pm

Nonstop1h 40m

Greenville

Tue 1/13

6:37 pm-8:31 pm

Nonstop1h 54m

$399

DetroitGreenville

DTW - GSP

DTWGSP

Detroit Metropolitan Wayne County

Fri 12/12

4:00 pm-5:49 pm

Nonstop1h 49m

Greenville

Tue 1/13

6:37 pm-8:31 pm

Nonstop1h 54m

$399

DetroitGreenville

DTW - GSP

DTWGSP

Detroit Metropolitan Wayne County

Fri 1/2

8:20 pm-10:06 pm

Nonstop1h 46m

Greenville

Wed 1/7

6:42 pm-8:36 pm

Nonstop1h 54m

$399

DetroitGreenville

DTW - GSP

DTWGSP

Detroit Metropolitan Wayne County

Sat 12/13

4:10 pm-5:50 pm

Nonstop1h 40m

Greenville

Sat 12/20

7:30 am-9:22 am

Nonstop1h 52m

$399

Flights are sorted by cheapest round-trip flights first.

Deals found on 10/28

Showing 1-10 of 21 results
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Compare providers for flights from Detroit to Greenville

Provider information is updated monthly. Please note that these providers often have deals for this flight, but the availability may vary on a day-by-day basis on Cheapflights.
Use the table below to compare price accuracy, trust ratings, and cancellation policies for each provider offering flight deals from Detroit to Greenville in October.
ProviderPrice AccuracyTrust Score*
ExpediaPrice Accuracy2 starsTrust Score*3 stars
FlightHubPrice Accuracy3 starsTrust Score*1 star
eDreamsPrice Accuracy3 starsTrust Score*3 stars
PricelinePrice Accuracy1 starTrust Score*3 stars

*The Trust Score is based on feedback from users after their booking experience. It measures overall satisfaction, helping us identify issues like hidden fees, problems during the ticketing process, and the quality of customer service. This score is our best indicator of the provider's quality and reliability.

  • Most accurate provider: When it comes to deals on Detroit Metropolitan Wayne County Airport-Greenville flights, users find the pricing of eDreams to be most consistent on Cheapflights vs. eDreams Users can find the same prices on Detroit Metropolitan Wayne County Airport-Greenville flight deals on Cheapflights vs. eDreams >95% of the time. Price accuracy is based on data collected from Detroit Metropolitan Wayne County Airport-Greenville flight searches over the past month and is updated monthly.
  • Most trusted provider: When it comes to deals on Detroit Metropolitan Wayne County Airport-Greenville flights, Cheapflights users trust eDreams the most. eDreams has received a user feedback score of 3 out of 3 stars (3 being the best), meaning they have been trusted the most by Cheapflights users looking for Detroit Metropolitan Wayne County Airport-Greenville flight deals. Provider user feedback score is based on Cheapflights searches over the past month and is updated monthly.

Best time to book a flight from Detroit to Greenville

Have a flexible travel schedule? Discover the best time to fly to Greenville from Detroit with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Detroit Metropolitan Wayne County Airport to Greenville

How far ahead should I book a flight from Detroit Metropolitan Wayne County Airport to Greenville?

Use this chart to determine the optimal time to book a round-trip flight from Detroit to Greenville. Price data was last updated on October 24, 2025.

The price you pay for your flight from Detroit Metropolitan Wayne County Airport to Greenville may vary depending on when you book. For the best chance of a lower fare, look to book 79 days in advance of your trip. Fares are likely to increase a fortnight or so before your departure date.

What is the cheapest month to book a flight from Detroit Metropolitan Wayne County Airport to Greenville?

Currently, September is the cheapest month in which you can book a flight from Detroit Metropolitan Wayne County Airport to Greenville (average of $108). Flying from Detroit Metropolitan Wayne County Airport to Greenville in April is currently the most expensive (average of $200). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

What is the cheapest time of day to fly from DTW to GSP?

Find hourly flight availability from Detroit to Greenville. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated October 29, 2025.

When flying from Detroit Metropolitan Wayne County Airport to Greenville, the time of day you fly usually plays a role in the price. Save by searching for a flight at noon, which can drop the price by up to 26% versus a flight in the evening.

What is the cheapest day to fly from Detroit Metropolitan Wayne County Airport to Greenville?

Use this chart to determine the cheapest time to fly round-trip from Detroit to Greenville. Price data was last updated on October 26, 2025.

Travelers seeking maximum savings on their Detroit Metropolitan Wayne County Airport to Greenville flight should consider departing on Wednesday at noon when fares are most often at their lowest. Sunday evenings flights should be avoided if possible as fares are typically the most expensive at this time.

How much does it cost to fly round-trip from Detroit Metropolitan Wayne County Airport to Greenville?

Reviews of airlines servicing Greenville

Get insights into the airlines that provide service to Greenville. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Greenville. Reviews last updated October 29, 2025.
See what other customers who have flown with Southwest, Delta, and American Airlines from Detroit Metropolitan Wayne County Airport to Greenville have to say. You can also see how each airline compares in terms of entertainment options, comfort, food, crew/service, and boarding process.
Southwest
8.0
Very good
4,241 reviews

Boarding

8.1

Overall

8.0

Food

7.0

Comfort

8.0

Crew

8.6

Entertainment

7.5

Reviews

1 / 20
2.0
Mediocre

Mike,Aug 2025

OKC - AUS

AC was not adequate, even on a night flight. WiFi subpar even for the airlines
Southwest
8.0
Very good
4,241 reviews
Southwest
8.0
Very good
4,241 reviews

Boarding

8.1

Overall

8.0

Food

7.0

Comfort

8.0

Crew

8.6

Entertainment

7.5

Reviews

1 / 20
2.0
Mediocre

Mike,Aug 2025

OKC - AUS

AC was not adequate, even on a night flight. WiFi subpar even for the airlines
Delta
7.9
Good
7,992 reviews
Southwest
8.0
Very good
4,241 reviews

Boarding

8.1

Overall

8.0

Food

7.0

Comfort

8.0

Crew

8.6

Entertainment

7.5

Reviews

1 / 20
2.0
Mediocre

Mike,Aug 2025

OKC - AUS

AC was not adequate, even on a night flight. WiFi subpar even for the airlines
American Airlines
7.2
Good
11,032 reviews
Southwest
8.0
Very good
4,241 reviews

Boarding

8.1

Overall

8.0

Food

7.0

Comfort

8.0

Crew

8.6

Entertainment

7.5

Reviews

1 / 20
2.0
Mediocre

Mike,Aug 2025

OKC - AUS

AC was not adequate, even on a night flight. WiFi subpar even for the airlines

Related info for your journey

Find useful and relevant information for your journey from Detroit to Greenville. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • What airports do I use to fly from Detroit to Greenville?

    If you book a flight from Detroit to Greenville, you will be flying from Detroit Metropolitan Wayne County to Greenville. Flights to Greenville (GSP) from Detroit Metropolitan Wayne County (DTW) take 1h 36m for a nonstop flight. There are 5 flights from Detroit Metropolitan Wayne County to Greenville per day from 3 airlines.

  • How long is the flight from Detroit Metropolitan Wayne County Airport to Greenville?

    American Airlines can get you from Detroit Metropolitan Wayne County Airport to Greenville in just under 8h 19m. Your travel time can differ by up to . The distance between Detroit Metropolitan Wayne County Airport and Greenville is about 510 mi.

  • What are the cheapest airlines flying from Detroit Metropolitan Wayne County Airport to Greenville round-trip?

    Cheapflights users have booked flights from Detroit Metropolitan Wayne County Airport to Greenville round-trip from $226. Other airlines that can offer you cheap pricing are Southwest, from $306, and Delta, from $397. American Airlines is currently priced 51% below the average price you’ll pay for this route.

  • What are the most reliable airlines from Detroit Metropolitan Wayne County Airport to Greenville?

    Looking for the most reliable airlines to get you to your destination on time? Our data shows these are most likely to get you from Detroit Metropolitan Wayne County Airport to Greenville on time: Delta (89%), WestJet (89%), Endeavor Airlines (88%).

  • What are the cheapest flights from Detroit Metropolitan Wayne County Airport to Greenville?

    While on average a flight from Detroit Metropolitan Wayne County Airport to Greenville is generally $429, our data shows the cheapest flight currently is $333. When looking at the most popular route, (Detroit Metropolitan Wayne County - Greenville), you can expect to pay $238 for that flight.

  • Can I find deals for flights from Detroit to Greenville that include hotel bookings?

    Yes. In addition to deals on Detroit to Greenville flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Detroit to Greenville?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Detroit to Greenville.

  • Can I find deals for business class flights from Detroit to Greenville?

    Yes. Cheapflights offers flight deals from Detroit to Greenville by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Detroit Metropolitan Wayne County Airport to Greenville?

    Currently, September is the cheapest month in which you can book a flight from Detroit Metropolitan Wayne County Airport to Greenville (average of $108). Flying from Detroit Metropolitan Wayne County Airport to Greenville in April is currently the most expensive (average of $200). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

Traveling to a place near Greenville?

Book flights to Greenville if you plan to visit one of these locations
Simpsonville
Duncan
Greer
Seneca
Anderson

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Top 3 airlines flying from Detroit to Greenville

Discover the top 3 airlines that operate flights from Detroit to Greenville. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated October 29, 2025.
AirlineCheapestAverageFlexibilityOn-time
American AirlinesCheapest$226Average$346FlexibilityNo cancel feeOn-time71%
SouthwestCheapest$306Average$361FlexibilityNo cancel feeOn-time63%
DeltaCheapest$397Average$497FlexibilityNo cancel feeOn-timeN/A

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