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$117+ Cheap flights from Detroit Metropolitan Wayne County Airport to Greenville (DTW - GSP)

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 12/9. Fares are subject to change and may not be available on all flights or dates of travel.
DTW — GSP
oct. 11 — oct. 181
sáb. 10/11
sáb. 10/18
1 adult, Economy
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Cheapflights Tip: The best prices from Detroit Metropolitan Wayne County to Greenville are usually found in February or September, booked 80 days in advance, depart on a Friday or Saturday and return on a Saturday

Cheap flight deals from Detroit to Greenville

Discover tips and strategies to find the most affordable flight options for your journey from Detroit (DTW) to Greenville (GSP). Learn about various techniques such as flexible date searches, comparing prices across and setting up price alerts. Use these methods to find the cheapest flights available for your travel needs. Data last updated septiembre 11, 2025.

Round-trip from

$222
(Kiwi.com)

One-way from

$117
(Southwest)

Popular in

August

Cheapest in

February

Average price

$399

Good round-trip deal

$579 or less

Good one-way deal

$308 or less
From Detroit Metropolitan Wayne County to Greenville
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One-way flight from Detroit Metropolitan Wayne County to Greenville
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Highest demand for flights based on searches. 3% potential increase in price ($14 potential increase over avg. RT price).
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Cheapest flight prices on average. 2% potential price decrease ($11 potential savings vs. average RT price).
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Average for round-trip flights in September 2025
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Price to beat on a round-trip flight from Detroit Metropolitan Wayne County to Greenville.
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Price to beat on a one-way flight from Detroit Metropolitan Wayne County to Greenville.
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Find flight deals from Detroit to Greenville

Cheapest flights from Detroit to Greenville
Explore the most affordable flight options available from Detroit to Greenville. Find the lowest fares from popular airlines and budget airlines, with prices last updated on septiembre 11, 2025.

This Southwest deal was found by Cheapflights users on 9/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
mié. 10/221:30 pmDTW - GSP
1 stop6h 25mSouthwest
mar. 10/286:05 amGSP - DTW
1 stop7h 00mSouthwest
Deal found 9/11$239
This Kiwi.com deal was found by Cheapflights users on 9/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
vie. 10/104:50 pmDTW - GSP
1 stop21h 58mMultiple Airlines
vie. 10/173:38 pmGSP - DTW
1 stop18h 02mMultiple Airlines
Deal found 9/11$246
This Southwest deal was found by Cheapflights users on 9/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
sáb. 11/155:35 amDTW - GSP
1 stop4h 10mSouthwest
mié. 11/1910:35 amGSP - DTW
1 stop4h 10mSouthwest
Deal found 9/11$252
This Kiwi.com deal was found by Cheapflights users on 9/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
vie. 10/1711:04 amDTW - GSP
1 stop8h 19mMultiple Airlines
lun. 10/208:03 pmGSP - DTW
1 stop15h 45mMultiple Airlines
Deal found 9/11$288
This Kiwi.com deal was found by Cheapflights users on 9/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
vie. 11/1412:16 pmDTW - GSP
1 stop7h 07mMultiple Airlines
lun. 11/178:03 pmGSP - DTW
2 stops20h 07mMultiple Airlines
Deal found 9/9$290
This Southwest deal was found by Cheapflights users on 9/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
mar. 11/115:40 amDTW - GSP
1 stop4h 20mSouthwest
vie. 11/148:00 amGSP - DTW
1 stop4h 10mSouthwest
Deal found 9/9$294
This American Airlines deal was found by Cheapflights users on 9/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
sáb. 10/49:18 amDTW - GSP
1 stop7h 41mAmerican Airlines
sáb. 10/111:39 pmGSP - DTW
1 stop8h 15mAmerican Airlines
Deal found 9/11$303
This American Airlines deal was found by Cheapflights users on 9/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
sáb. 12/138:17 amDTW - GSP
1 stop10h 25mAmerican Airlines
mar. 1/137:48 amGSP - DTW
1 stop8h 55mAmerican Airlines
Deal found 9/11$305

Cheapflights Fare Finder

 
Customize your flight search to find flights from Detroit to Greenville that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated septiembre 11, 2025.
Use the filters below to find and compare flights from Detroit Metropolitan Wayne County Airport to Greenville that are best for you.

Fly from

Detroit

Fly to

Greenville

Route

Depart

Return

Price

DetroitGreenville

DTW - GSP

DTWGSP

Detroit Metropolitan Wayne County

mié. 10/22

1:30 pm-7:55 pm

1 stop6h 25m

Greenville

mié. 10/29

3:00 pm-11:00 pm

2 stops8h 00m

$239

DetroitGreenville

DTW - GSP

DTWGSP

Detroit Metropolitan Wayne County

vie. 10/10

4:50 pm-2:48 pm

1 stop21h 58m

Greenville

vie. 10/17

3:38 pm-9:40 am

1 stop18h 02m

$246

DetroitGreenville

DTW - GSP

DTWGSP

Detroit Metropolitan Wayne County

mar. 11/11

5:40 am-10:00 am

1 stop4h 20m

Greenville

vie. 11/14

8:00 am-12:10 pm

1 stop4h 10m

$294

DetroitGreenville

DTW - GSP

DTWGSP

Detroit Metropolitan Wayne County

mié. 10/22

1:30 pm-7:55 pm

1 stop6h 25m

Greenville

mar. 10/28

3:00 pm-11:00 pm

2 stops8h 00m

$299

DetroitGreenville

DTW - GSP

DTWGSP

Detroit Metropolitan Wayne County

vie. 10/24

11:04 am-7:23 pm

1 stop8h 19m

Greenville

dom. 10/26

10:33 am-12:45 am

2 stops14h 12m

$362

DetroitGreenville

DTW - GSP

DTWGSP

Detroit Metropolitan Wayne County

vie. 11/14

12:25 pm-9:35 pm

2 stops9h 10m

Greenville

lun. 11/17

7:40 am-5:50 pm

2 stops10h 10m

$396

DetroitGreenville

DTW - GSP

DTWGSP

Detroit Metropolitan Wayne County

jue. 10/16

8:59 am-10:48 am

Nonstop1h 49m

Greenville

dom. 10/19

7:30 am-9:18 am

Nonstop1h 48m

$399

DetroitGreenville

DTW - GSP

DTWGSP

Detroit Metropolitan Wayne County

dom. 11/9

1:44 pm-7:23 pm

2 stops29h 39m

$125

DetroitGreenville

DTW - GSP

DTWGSP

Detroit Metropolitan Wayne County

mié. 10/15

7:15 pm-8:44 pm

1 stop25h 29m

$125

DetroitGreenville

DTW - GSP

DTWGSP

Detroit Metropolitan Wayne County

mié. 11/12

9:20 pm-9:16 am

2 stops35h 56m

$127

Flights are sorted by cheapest round-trip flights first.

Deals found on 9/9

Showing 1-10 of 18 results
1
2

Best time to book a flight from Detroit to Greenville

Have a flexible travel schedule? Discover the best time to fly to Greenville from Detroit with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Detroit Metropolitan Wayne County Airport to Greenville

How far ahead should I book a flight from Detroit Metropolitan Wayne County Airport to Greenville?

Use this chart to determine the optimal time to book a round-trip flight from Detroit to Greenville. Price data was last updated on August 29, 2025.

The price you pay for your flight from Detroit Metropolitan Wayne County Airport to Greenville may vary depending on when you book. For the best chance of a lower fare, look to book 79 days in advance of your trip. Fares are likely to increase a fortnight or so before your departure date.

What is the cheapest month to book a flight from Detroit Metropolitan Wayne County Airport to Greenville?

Currently, August is the cheapest month in which you can book a flight from Detroit Metropolitan Wayne County Airport to Greenville (average of $322). Flying from Detroit Metropolitan Wayne County Airport to Greenville in March is currently the most expensive (average of $386). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

What is the cheapest time of day to fly from DTW to GSP?

Find hourly flight availability from Detroit to Greenville. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated septiembre 11, 2025.

When flying from Detroit Metropolitan Wayne County Airport to Greenville, the time of day you fly usually plays a role in the price. Save by searching for a flight in the afternoon, which can drop the price by up to 11% versus a flight in the morning.

What is the cheapest day to fly from Detroit Metropolitan Wayne County Airport to Greenville?

Use this chart to determine the cheapest time to fly round-trip from Detroit to Greenville. Price data was last updated on September 7, 2025.

Travelers seeking maximum savings on their Detroit Metropolitan Wayne County Airport to Greenville flight should consider departing on Tuesday evenings when fares are most often at their lowest. Monday evenings flights should be avoided if possible as fares are typically the most expensive at this time.

Reviews of airlines servicing Greenville

Get insights into the airlines that provide service to Greenville. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Greenville. Reviews last updated septiembre 11, 2025.
See what other customers who have flown with Southwest, Delta, and American Airlines from Detroit Metropolitan Wayne County Airport to Greenville have to say. You can also see how each airline compares in terms of entertainment options, comfort, food, crew/service, and boarding process.
Southwest
8.0
Very good
4,248 reviews

Entertainment

7.5

Boarding

8.1

Comfort

8.0

Crew

8.6

Overall

8.0

Food

7.0

Reviews

1 / 20
2.0
Mediocre

Mike,Aug 2025

OKC - AUS

AC was not adequate, even on a night flight. WiFi subpar even for the airlines
Southwest
8.0
Very good
4,248 reviews
Southwest
8.0
Very good
4,248 reviews

Entertainment

7.5

Boarding

8.1

Comfort

8.0

Crew

8.6

Overall

8.0

Food

7.0

Reviews

1 / 20
2.0
Mediocre

Mike,Aug 2025

OKC - AUS

AC was not adequate, even on a night flight. WiFi subpar even for the airlines
Delta
8.0
Very good
7,960 reviews
Southwest
8.0
Very good
4,248 reviews

Entertainment

7.5

Boarding

8.1

Comfort

8.0

Crew

8.6

Overall

8.0

Food

7.0

Reviews

1 / 20
2.0
Mediocre

Mike,Aug 2025

OKC - AUS

AC was not adequate, even on a night flight. WiFi subpar even for the airlines
American Airlines
7.2
Good
10,000 reviews
Southwest
8.0
Very good
4,248 reviews

Entertainment

7.5

Boarding

8.1

Comfort

8.0

Crew

8.6

Overall

8.0

Food

7.0

Reviews

1 / 20
2.0
Mediocre

Mike,Aug 2025

OKC - AUS

AC was not adequate, even on a night flight. WiFi subpar even for the airlines

Related info for your journey

Find useful and relevant information for your journey from Detroit to Greenville. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • What airports do I use to fly from Detroit to Greenville?

    If you book a flight from Detroit to Greenville, you will be flying from Detroit Metropolitan Wayne County to Greenville. Flights to Greenville (GSP) from Detroit Metropolitan Wayne County (DTW) take 1h 35m for a nonstop flight. There are 9 flights from Detroit Metropolitan Wayne County to Greenville per day from 3 airlines.

  • How long is the flight from Detroit Metropolitan Wayne County Airport to Greenville?

    Southwest can get you from Detroit Metropolitan Wayne County Airport to Greenville in just under 6h 25m. Your travel time can differ by up to . The distance between Detroit Metropolitan Wayne County Airport and Greenville is about 510 mi.

  • What are the cheapest airlines flying from Detroit Metropolitan Wayne County Airport to Greenville round-trip?

    Cheapflights users have booked flights from Detroit Metropolitan Wayne County Airport to Greenville round-trip from $236. Other airlines that can offer you cheap pricing are Southwest, from $306, and Delta, from $372. American Airlines is currently priced 47% below the average price you’ll pay for this route.

  • What are the most reliable airlines from Detroit Metropolitan Wayne County Airport to Greenville?

    Looking for the most reliable airlines to get you to your destination on time? Our data shows these are most likely to get you from Detroit Metropolitan Wayne County Airport to Greenville on time: SkyWest Airlines (90%), WestJet (89%), Air France (88%).

  • What are the cheapest flights from Detroit Metropolitan Wayne County Airport to Greenville?

    While on average a flight from Detroit Metropolitan Wayne County Airport to Greenville is generally $461, our data shows the cheapest flight currently is $266. When looking at the most popular route, (Detroit Metropolitan Wayne County - Greenville), you can expect to pay $222 for that flight.

  • Can I find deals for flights from Detroit to Greenville that include hotel bookings?

    Yes. In addition to deals on Detroit to Greenville flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Detroit to Greenville?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Detroit to Greenville.

  • Can I find deals for business class flights from Detroit to Greenville?

    Yes. Cheapflights offers flight deals from Detroit to Greenville by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Detroit Metropolitan Wayne County Airport to Greenville?

    Currently, August is the cheapest month in which you can book a flight from Detroit Metropolitan Wayne County Airport to Greenville (average of $322). Flying from Detroit Metropolitan Wayne County Airport to Greenville in March is currently the most expensive (average of $386). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

Traveling to a place near Greenville?

Book flights to Greenville if you plan to visit one of these locations
Simpsonville
Duncan
Seneca
Anderson

Browse thousands of different options on Cheapflights for your next trip

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Top 3 airlines flying from Detroit to Greenville

Discover the top 3 airlines that operate flights from Detroit to Greenville. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated septiembre 11, 2025.
AirlineCheapestAverageFlexibilityOn-time
American AirlinesCheapest$236Average$386FlexibilityNo cancel feeOn-time71%
SouthwestCheapest$306Average$366FlexibilityNo cancel feeOn-time63%
DeltaCheapest$372Average$474FlexibilityNo cancel feeOn-timeN/A

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