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Greenville

$108+ Cheap flights from Detroit Metropolitan Wayne County Airport to Greenville (DTW - GSP)

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 2/25. Fares are subject to change and may not be available on all flights or dates of travel.
DTW — GSP
Feb 27 — Mar 61
Fri 2/27
Fri 3/6
1 adult, Economy
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Cheap flight deals from Detroit to Greenville

Cheapest flights from Detroit to Greenville
Explore the most affordable flight options available from Detroit to Greenville. Find the lowest fares from popular airlines and budget airlines, with prices last updated on January 28, 2026.

This Kiwi.com deal was found by Cheapflights users on 1/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 2/25:15 am
DTW
-
GSP
1 stop10h 44m
Multiple Airlines
Thu 2/55:45 pm
GSP
-
DTW
1 stop16h 20m
Multiple Airlines
Deal found 1/26$268
This Kiwi.com deal was found by Cheapflights users on 1/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 2/25:15 am
DTW
-
GSP
1 stop10h 44m
Multiple Airlines
Sun 2/85:45 pm
GSP
-
DTW
2 stops24h 34m
Multiple Airlines
Deal found 1/26$276
This Kiwi.com deal was found by Cheapflights users on 1/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 2/25:15 am
DTW
-
GSP
1 stop10h 44m
Multiple Airlines
Fri 2/69:48 am
GSP
-
DTW
1 stop14h 11m
Multiple Airlines
Deal found 1/26$281
This Kiwi.com deal was found by Cheapflights users on 1/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 2/285:26 pm
DTW
-
GSP
2 stops18h 37m
Multiple Airlines
Mon 3/26:49 pm
GSP
-
DTW
1 stop14h 26m
Multiple Airlines
Deal found 1/26$288
This Kiwi.com deal was found by Cheapflights users on 1/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 3/155:34 pm
DTW
-
GSP
2 stops23h 41m
Multiple Airlines
Sun 3/229:46 pm
GSP
-
DTW
1 stop26h 53m
Multiple Airlines
Deal found 1/26$290
This Southwest deal was found by Cheapflights users on 1/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 2/255:25 am
DTW
-
GSP
1 stop5h 15m
Southwest
Thu 2/268:30 am
GSP
-
DTW
1 stop3h 50m
Southwest
Deal found 1/26$293
This Kiwi.com deal was found by Cheapflights users on 1/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 2/1310:29 pm
DTW
-
GSP
2 stops39h 45m
Multiple Airlines
Thu 2/195:17 pm
GSP
-
DTW
1 stop15h 58m
Multiple Airlines
Deal found 1/27$300
This Kiwi.com deal was found by Cheapflights users on 1/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 2/112:36 pm
DTW
-
GSP
2 stops22h 36m
Multiple Airlines
Sun 2/155:17 pm
GSP
-
DTW
1 stop6h 42m
Multiple Airlines
Deal found 1/27$308
This Kiwi.com deal was found by Cheapflights users on 1/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 3/196:05 am
DTW
-
GSP
2 stops14h 51m
Multiple Airlines
Mon 3/234:28 pm
GSP
-
DTW
1 stop16h 55m
Multiple Airlines
Deal found 1/26$311
This Kiwi.com deal was found by Cheapflights users on 1/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 2/199:02 am
DTW
-
GSP
1 stop7h 25m
Multiple Airlines
Sun 2/225:17 pm
GSP
-
DTW
2 stops27h 48m
Multiple Airlines
Deal found 1/26$314

Find flight deals from Detroit to Greenville

Discover tips and strategies to find the most affordable flight options for your journey from Detroit (DTW) to Greenville (GSP). Learn about various techniques such as flexible date searches, comparing prices across and setting up price alerts. Use these methods to find the cheapest flights available for your travel needs. Data last updated January 28, 2026.

Most accurate provider

FlightHub
3 stars

Most trusted provider

FlightHub
3 stars

Round-trip from

$276
(Kiwi.com)

One-way from

$108
(Kiwi.com)

Popular in

November

Cheapest in

February

Average price

$489

Good round-trip deal

$399 or less

Good one-way deal

$333 or less
Provider with most accurate pricing for Detroit Metropolitan Wayne County-Greenville flight deals.
Search Deals
Provider most trusted by Cheapflights users for Detroit Metropolitan Wayne County-Greenville flights.
Search Deals
From Detroit Metropolitan Wayne County to Greenville
Search Deals
One-way flight from Detroit Metropolitan Wayne County to Greenville
Search Deals
Highest demand for flights based on searches. 15% potential increase in price ($84 potential increase over avg. RT price).
Search Deals
Cheapest flight prices on average. 2% potential price decrease ($13 potential savings vs. average RT price).
Search Deals
Average for round-trip flights in January 2026
Search Deals
Price to beat on a round-trip flight from Detroit Metropolitan Wayne County to Greenville.
Search Deals
Price to beat on a one-way flight from Detroit Metropolitan Wayne County to Greenville.
Search Deals

Cheapflights Fare Finder

 
Customize your flight search to find flights from Detroit to Greenville that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated January 28, 2026.
Use the filters below to find and compare flights from Detroit Metropolitan Wayne County Airport to Greenville that are best for you.

Fly from

Detroit

Fly to

Greenville

Route

Depart

Return

Price

DetroitGreenville

DTW - GSP

DTWGSP

Detroit Metropolitan Wayne County

Wed 2/25

5:25 am-10:40 am

1 stop5h 15m

Greenville

Thu 2/26

8:30 am-12:20 pm

1 stop3h 50m

$293

DetroitGreenville

DTW - GSP

DTWGSP

Detroit Metropolitan Wayne County

Thu 3/19

6:05 am-8:56 pm

2 stops14h 51m

Greenville

Mon 3/23

4:28 pm-9:23 am

1 stop16h 55m

$311

DetroitGreenville

DTW - GSP

DTWGSP

Detroit Metropolitan Wayne County

Thu 2/19

9:02 am-4:27 pm

1 stop7h 25m

Greenville

Sun 2/22

5:17 pm-9:05 pm

2 stops27h 48m

$314

DetroitGreenville

DTW - GSP

DTWGSP

Detroit Metropolitan Wayne County

Mon 2/9

5:00 am-7:38 pm

2 stops14h 38m

Greenville

Thu 2/12

5:17 pm-7:40 pm

1 stop26h 23m

$336

DetroitGreenville

DTW - GSP

DTWGSP

Detroit Metropolitan Wayne County

Thu 5/28

3:35 pm-8:55 pm

1 stop5h 20m

Greenville

Sun 5/31

7:05 pm-11:05 pm

1 stop4h 00m

$343

DetroitGreenville

DTW - GSP

DTWGSP

Detroit Metropolitan Wayne County

Tue 2/24

6:50 am-5:40 pm

2 stops10h 50m

Greenville

Tue 3/3

11:15 am-3:05 pm

1 stop3h 50m

$348

DetroitGreenville

DTW - GSP

DTWGSP

Detroit Metropolitan Wayne County

Thu 2/26

8:46 pm-8:07 pm

1 stop23h 21m

Greenville

Thu 3/5

2:12 pm-1:41 am

1 stop11h 29m

$349

DetroitGreenville

DTW - GSP

DTWGSP

Detroit Metropolitan Wayne County

Fri 3/6

6:05 am-8:07 pm

1 stop14h 02m

Greenville

Sun 3/8

4:41 pm-9:15 am

1 stop16h 34m

$359

DetroitGreenville

DTW - GSP

DTWGSP

Detroit Metropolitan Wayne County

Tue 2/10

2:02 pm-10:16 pm

1 stop8h 14m

Greenville

Tue 2/17

7:20 am-4:48 pm

1 stop9h 28m

$381

DetroitGreenville

DTW - GSP

DTWGSP

Detroit Metropolitan Wayne County

Thu 2/26

9:00 am-5:59 pm

2 stops32h 59m

$131

Flights are sorted by cheapest round-trip flights first.

Deals found on 1/27

Showing 1-10 of 17 results
1
2

Compare providers for flights from Detroit to Greenville

Provider information is updated monthly. Please note that these providers often have deals for this flight, but the availability may vary on a day-by-day basis on Cheapflights.
Use the table below to compare price accuracy, trust ratings, and cancellation policies for each provider offering flight deals from Detroit to Greenville in January.
ProviderPrice AccuracyTrust Score*
ExpediaPrice Accuracy1 starTrust Score*3 stars
FlightHubPrice Accuracy3 starsTrust Score*3 stars
PricelinePrice Accuracy1 starTrust Score*3 stars

*The Trust Score is based on feedback from users after their booking experience. It measures overall satisfaction, helping us identify issues like hidden fees, problems during the ticketing process, and the quality of customer service. This score is our best indicator of the provider's quality and reliability.

  • Most accurate provider: When it comes to deals on Detroit Metropolitan Wayne County Airport-Greenville flights, users find the pricing of FlightHub to be most consistent on Cheapflights vs. FlightHub Users can find the same prices on Detroit Metropolitan Wayne County Airport-Greenville flight deals on Cheapflights vs. FlightHub >95% of the time. Price accuracy is based on data collected from Detroit Metropolitan Wayne County Airport-Greenville flight searches over the past month and is updated monthly.
  • Most trusted provider: When it comes to deals on Detroit Metropolitan Wayne County Airport-Greenville flights, Cheapflights users trust FlightHub the most. FlightHub has received a user feedback score of 3 out of 3 stars (3 being the best), meaning they have been trusted the most by Cheapflights users looking for Detroit Metropolitan Wayne County Airport-Greenville flight deals. Provider user feedback score is based on Cheapflights searches over the past month and is updated monthly.

Best time to book a flight from Detroit to Greenville

Have a flexible travel schedule? Discover the best time to fly to Greenville from Detroit with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Detroit Metropolitan Wayne County Airport to Greenville

What is the cheapest month to book a flight from Detroit Metropolitan Wayne County Airport to Greenville?

Currently, August is the cheapest month in which you can book a flight from Detroit Metropolitan Wayne County Airport to Greenville (average of $109). Flying from Detroit Metropolitan Wayne County Airport to Greenville in April is currently the most expensive (average of $202). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

What is the cheapest time of day to fly from DTW to GSP?

Find hourly flight availability from Detroit to Greenville. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated January 28, 2026.

When flying from Detroit Metropolitan Wayne County Airport to Greenville, the time of day you fly usually plays a role in the price. Save by searching for a flight at noon, which can drop the price by up to 33% versus a flight in the evening.

Reviews of airlines servicing Greenville

Get insights into the airlines that provide service to Greenville. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Greenville. Reviews last updated January 28, 2026.
See what other customers who have flown with Southwest, Delta, and American Airlines from Detroit Metropolitan Wayne County Airport to Greenville have to say. You can also see how each airline compares in terms of entertainment options, comfort, food, crew/service, and boarding process.
Southwest
8.0
Very good
4,268 reviews

Boarding

8.1

Comfort

8.0

Entertainment

7.5

Crew

8.6

Overall

8.0

Food

7.0

Reviews

1 / 20
2.0
Mediocre

Thomas,Dec 2025

SEA - DEN

Plane two hours late in leaving 1:00 pm west coat time got home next day at 2:45am most car rental places are closed and don’t open till 5am
Southwest
8.0
Very good
4,268 reviews
Southwest
8.0
Very good
4,268 reviews

Boarding

8.1

Comfort

8.0

Entertainment

7.5

Crew

8.6

Overall

8.0

Food

7.0

Reviews

1 / 20
2.0
Mediocre

Thomas,Dec 2025

SEA - DEN

Plane two hours late in leaving 1:00 pm west coat time got home next day at 2:45am most car rental places are closed and don’t open till 5am
Delta
7.9
Good
8,120 reviews
Southwest
8.0
Very good
4,268 reviews

Boarding

8.1

Comfort

8.0

Entertainment

7.5

Crew

8.6

Overall

8.0

Food

7.0

Reviews

1 / 20
2.0
Mediocre

Thomas,Dec 2025

SEA - DEN

Plane two hours late in leaving 1:00 pm west coat time got home next day at 2:45am most car rental places are closed and don’t open till 5am
American Airlines
7.2
Good
11,198 reviews
Southwest
8.0
Very good
4,268 reviews

Boarding

8.1

Comfort

8.0

Entertainment

7.5

Crew

8.6

Overall

8.0

Food

7.0

Reviews

1 / 20
2.0
Mediocre

Thomas,Dec 2025

SEA - DEN

Plane two hours late in leaving 1:00 pm west coat time got home next day at 2:45am most car rental places are closed and don’t open till 5am

Related info for your journey

Find useful and relevant information for your journey from Detroit to Greenville. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • What airports do I use to fly from Detroit to Greenville?

    If you book a flight from Detroit to Greenville, you will be flying from Detroit Metropolitan Wayne County to Greenville. Flights to Greenville (GSP) from Detroit Metropolitan Wayne County (DTW) take 1h 45m for a nonstop flight. There are 9 flights from Detroit Metropolitan Wayne County to Greenville per day from 3 airlines.

  • How long is the flight from Detroit Metropolitan Wayne County Airport to Greenville?

    Southwest can get you from Detroit Metropolitan Wayne County Airport to Greenville in just under 5h 15m. Your travel time can differ by up to . The distance between Detroit Metropolitan Wayne County Airport and Greenville is about 510 mi.

  • What are the cheapest airlines flying from Detroit Metropolitan Wayne County Airport to Greenville round-trip?

    Cheapflights users have booked flights from Detroit Metropolitan Wayne County Airport to Greenville round-trip from $226. Other airlines that can offer you cheap pricing are Southwest, from $306, and Delta, from $399. American Airlines is currently priced 51% below the average price you’ll pay for this route.

  • What are the most reliable airlines from Detroit Metropolitan Wayne County Airport to Greenville?

    Looking for the most reliable airlines to get you to your destination on time? Our data shows these are most likely to get you from Detroit Metropolitan Wayne County Airport to Greenville on time: Virgin Atlantic (73%), WestJet (71%), Aeromexico (70%).

  • What are the cheapest flights from Detroit Metropolitan Wayne County Airport to Greenville?

    While on average a flight from Detroit Metropolitan Wayne County Airport to Greenville is generally $513, our data shows the cheapest flight currently is $333. When looking at the most popular route, (Detroit Metropolitan Wayne County - Greenville), you can expect to pay $293 for that flight.

  • Can I find deals for flights from Detroit to Greenville that include hotel bookings?

    Yes. In addition to deals on Detroit to Greenville flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Detroit to Greenville?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Detroit to Greenville.

  • Can I find deals for business class flights from Detroit to Greenville?

    Yes. Cheapflights offers flight deals from Detroit to Greenville by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Detroit Metropolitan Wayne County Airport to Greenville?

    Currently, August is the cheapest month in which you can book a flight from Detroit Metropolitan Wayne County Airport to Greenville (average of $109). Flying from Detroit Metropolitan Wayne County Airport to Greenville in April is currently the most expensive (average of $202). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

Traveling to a place near Greenville?

Book flights to Greenville if you plan to visit one of these locations
Simpsonville
Duncan
Greer
Seneca
Anderson

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Top 3 airlines flying from Detroit to Greenville

Discover the top 3 airlines that operate flights from Detroit to Greenville. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated January 28, 2026.
AirlineCheapestAverageFlexibilityOn-time
American AirlinesCheapest$226Average$326FlexibilityNo cancel feeOn-time71%
SouthwestCheapest$306Average$326FlexibilityNo cancel feeOn-time63%
DeltaCheapest$399Average$522FlexibilityNo cancel feeOn-timeN/A

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