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$643+ Cheap flights from Panama City (PTY) to Greenville, NC (PGV)

This is the cheapest round-trip flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 12/26. Fares are subject to change and may not be available on all flights or dates of travel.
PTY — PGV
Jan 3 — Jan 101
Sat 1/3
Sat 1/10
1 adult, Economy
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Cheap flight deals from Panama City to Greenville

Cheapest flights from Panama City to Greenville
Explore the most affordable flight options available from Panama City to Greenville. Find the lowest fares from popular airlines and budget airlines, with prices last updated on December 4, 2025.

This American Airlines deal was found by Cheapflights users on 12/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 12/262:53 pmPTY - PGV
2 stops19h 43mAmerican Airlines
Tue 12/305:56 pmPGV - PTY
2 stops19h 57mAmerican Airlines
Deal found 12/1$643

Find flight deals from Panama City to Greenville

Discover tips and strategies to find the most affordable flight options for your journey from Panama City (PTY) to Greenville (PGV). Learn about various techniques such as flexible date searches, comparing prices across and setting up price alerts. Use these methods to find the cheapest flights available for your travel needs. Data last updated December 4, 2025.

Most accurate provider

Expedia
2 stars

Most trusted provider

Expedia
3 stars

Round-trip from

$643
(American Airlines)
Provider with most accurate pricing for Panama City Tocumen Intl-Pitt-Greenville flight deals.
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Provider most trusted by Cheapflights users for Panama City Tocumen Intl-Pitt-Greenville flights.
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From Panama City Tocumen Intl to Pitt-Greenville
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Cheapflights Fare Finder

 
Customize your flight search to find flights from Panama City to Greenville that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated December 4, 2025.
Use the filters below to find and compare flights from Panama City to Greenville that are best for you.

Fly from

Panama City

Fly to

Greenville

Route

Depart

Return

Price

Panama CityGreenville

PTY - PGV

PTYPGV

Panama City Tocumen Intl

Fri 12/26

2:53 pm-10:36 am

2 stops19h 43m

Pitt-Greenville

Tue 12/30

5:56 pm-1:53 pm

2 stops19h 57m

$643

Flights are sorted by cheapest round-trip flights first.

Deals found on 12/1

  • Most accurate provider: When it comes to deals on Panama City-Greenville, North Carolina flights, users find the pricing of Expedia to be most consistent on Cheapflights vs. Expedia Users can find the same prices on Panama City-Greenville, North Carolina flight deals on Cheapflights vs. Expedia 90-95% of the time. Price accuracy is based on data collected from Panama City-Greenville, North Carolina flight searches over the past month and is updated monthly.
  • Most trusted provider: When it comes to deals on Panama City-Greenville, North Carolina flights, Cheapflights users trust Expedia the most. Expedia has received a user feedback score of 3 out of 3 stars (3 being the best), meaning they have been trusted the most by Cheapflights users looking for Panama City-Greenville, North Carolina flight deals. Provider user feedback score is based on Cheapflights searches over the past month and is updated monthly.

Best time to book a flight from Panama City to Greenville

Have a flexible travel schedule? Discover the best time to fly to Greenville from Panama City with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Panama City to Greenville

What is the cheapest month to book a flight from Panama City to Greenville, North Carolina?

Currently, June is the cheapest month in which you can book a flight from Panama City to Greenville, North Carolina (average of $273). Flying from Panama City to Greenville, North Carolina in November is currently the most expensive (average of $429). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

Related info for your journey

Find useful and relevant information for your journey from Panama City to Greenville. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • How long is the flight from Panama City to Greenville, North Carolina?

    American Airlines can get you from Panama City to Greenville, North Carolina in just under 19h 43m. Your travel time can differ by up to . The distance from Panama City to Greenville, North Carolina is about 1838 mi.

  • Can I find deals for flights from Panama City to Greenville that include hotel bookings?

    Yes. In addition to deals on Panama City to Greenville flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Panama City to Greenville?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Panama City to Greenville.

  • Can I find deals for business class flights from Panama City to Greenville?

    Yes. Cheapflights offers flight deals from Panama City to Greenville by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Panama City to Greenville, North Carolina?

    Currently, June is the cheapest month in which you can book a flight from Panama City to Greenville, North Carolina (average of $273). Flying from Panama City to Greenville, North Carolina in November is currently the most expensive (average of $429). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

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