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$207+ Cheap flights from Florida Keys to Gainesville (GNV)

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 10/15. Fares are subject to change and may not be available on all flights or dates of travel.
EYW — GNV
Oct 15 — Oct 221
Wed 10/15
Wed 10/22
1 adult, Economy
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Cheap flight deals from Florida Keys to Gainesville

Keep the following information in mind while searching for Florida Keys to Gainesville flight deals. Data was last updated September 15, 2025.

Round-trip from

$284
(American Airlines)

One-way from

$207
(Delta)
From Florida Keys to Gainesville Regional
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One-way flight from Florida Keys to Gainesville Regional
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Find flight deals from Florida Keys to Gainesville

Cheapest flights from Florida Keys to Gainesville
Explore the most affordable flight options available from Florida Keys to Gainesville. Find the lowest fares from popular airlines and budget airlines, with prices last updated on September 15, 2025.

This American Airlines deal was found by Cheapflights users on 9/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 12/118:05 pmEYW - GNV
1 stop3h 53mAmerican Airlines
Sun 12/146:00 amGNV - EYW
1 stop5h 02mAmerican Airlines
Deal found 9/15$284
This American Airlines deal was found by Cheapflights users on 9/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/1710:43 pmMIA - GNV
Nonstop1h 12mAmerican Airlines
Wed 10/226:00 amGNV - MIA
Nonstop1h 11mAmerican Airlines
Deal found 9/14$367
This American Airlines deal was found by Cheapflights users on 9/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 10/1810:43 pmMIA - GNV
Nonstop1h 12mAmerican Airlines
Sun 10/196:00 amGNV - MIA
Nonstop1h 11mAmerican Airlines
Deal found 9/14$369
This American Airlines deal was found by Cheapflights users on 9/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 10/1110:43 pmMIA - GNV
Nonstop1h 12mAmerican Airlines
Wed 10/226:00 amGNV - MIA
Nonstop1h 11mAmerican Airlines
Deal found 9/14$378
This American Airlines deal was found by Cheapflights users on 9/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 10/1310:43 pmMIA - GNV
Nonstop1h 12mAmerican Airlines
Mon 10/206:00 amGNV - MIA
Nonstop1h 11mAmerican Airlines
Deal found 9/13$387
This American Airlines deal was found by Cheapflights users on 9/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 9/307:31 pmEYW - GNV
1 stop4h 28mAmerican Airlines
Sat 10/46:13 amGNV - EYW
1 stop4h 41mAmerican Airlines
Deal found 9/14$398
This Delta deal was found by Cheapflights users on 9/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 12/23:50 pmMIA - GNV
1 stop7h 20mDelta
Sat 12/64:10 pmGNV - MIA
1 stop8h 36mDelta
Deal found 9/14$405
This American Airlines deal was found by Cheapflights users on 9/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 12/210:39 pmMIA - GNV
Nonstop1h 20mAmerican Airlines
Sat 12/66:00 amGNV - MIA
Nonstop1h 16mAmerican Airlines
Deal found 9/14$407
This American Airlines deal was found by Cheapflights users on 9/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 9/2010:46 pmMIA - GNV
Nonstop1h 13mAmerican Airlines
Sat 9/276:13 amGNV - MIA
Nonstop1h 11mAmerican Airlines
Deal found 9/13$409
This American Airlines deal was found by Cheapflights users on 9/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 12/210:39 pmMIA - GNV
Nonstop1h 20mAmerican Airlines
Sun 12/76:00 amGNV - MIA
Nonstop1h 16mAmerican Airlines
Deal found 9/14$427
This American Airlines deal was found by Cheapflights users on 9/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/1010:43 pmMIA - GNV
Nonstop1h 12mAmerican Airlines
Tue 10/146:00 amGNV - MIA
Nonstop1h 11mAmerican Airlines
Deal found 9/12$437
This American Airlines deal was found by Cheapflights users on 9/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 10/1210:43 pmMIA - GNV
Nonstop1h 12mAmerican Airlines
Sun 10/196:00 amGNV - MIA
Nonstop1h 11mAmerican Airlines
Deal found 9/14$457

Cheapflights Fare Finder

 
Customize your flight search to find flights from Florida Keys to Gainesville that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated September 15, 2025.
Use the filters below to find and compare flights from Florida Keys to Gainesville that are best for you.

Fly from

Florida Keys

Fly to

Gainesville

Route

Depart

Return

Price

Key WestGainesville

EYW - GNV

EYWGNV

Key West

Thu 12/11

8:05 pm-11:58 pm

1 stop3h 53m

Gainesville Regional

Sun 12/14

6:00 am-11:02 am

1 stop5h 02m

$284

MiamiGainesville

MIA - GNV

MIAGNV

Miami

Fri 10/17

10:43 pm-11:55 pm

Nonstop1h 12m

Gainesville Regional

Wed 10/22

6:00 am-7:11 am

Nonstop1h 11m

$367

MiamiGainesville

MIA - GNV

MIAGNV

Miami

Sat 10/18

10:43 pm-11:55 pm

Nonstop1h 12m

Gainesville Regional

Sun 10/19

6:00 am-7:11 am

Nonstop1h 11m

$369

MiamiGainesville

MIA - GNV

MIAGNV

Miami

Sat 10/11

10:43 pm-11:55 pm

Nonstop1h 12m

Gainesville Regional

Sat 10/18

6:00 am-7:11 am

Nonstop1h 11m

$378

MiamiGainesville

MIA - GNV

MIAGNV

Miami

Sat 10/11

10:43 pm-11:55 pm

Nonstop1h 12m

Gainesville Regional

Wed 10/22

6:00 am-7:11 am

Nonstop1h 11m

$378

MiamiGainesville

MIA - GNV

MIAGNV

Miami

Thu 10/30

10:43 pm-11:55 pm

Nonstop1h 12m

Gainesville Regional

Sun 11/2

5:00 am-6:14 am

Nonstop1h 14m

$387

MiamiGainesville

MIA - GNV

MIAGNV

Miami

Fri 10/17

10:43 pm-11:55 pm

Nonstop1h 12m

Gainesville Regional

Sun 10/19

6:00 am-7:11 am

Nonstop1h 11m

$387

Key WestGainesville

EYW - GNV

EYWGNV

Key West

Tue 9/30

7:31 pm-11:59 pm

1 stop4h 28m

Gainesville Regional

Sat 10/4

6:13 am-10:54 am

1 stop4h 41m

$398

MiamiGainesville

MIA - GNV

MIAGNV

Miami

Tue 12/2

3:50 pm-11:10 pm

1 stop7h 20m

Gainesville Regional

Sat 12/6

4:10 pm-12:46 am

1 stop8h 36m

$405

MiamiGainesville

MIA - GNV

MIAGNV

Miami

Mon 12/1

10:39 pm-11:59 pm

Nonstop1h 20m

Gainesville Regional

Sun 12/7

6:00 am-7:16 am

Nonstop1h 16m

$427

Flights are sorted by cheapest round-trip flights first.

Deals found on 9/12

Showing 1-10 of 23 results
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Best time to book a flight from Florida Keys to Gainesville

Have a flexible travel schedule? Discover the best time to fly to Gainesville from Florida Keys with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Florida Keys to Gainesville

What is the cheapest month to book a flight from Florida Keys to Gainesville?

Currently, January is the cheapest month in which you can book a flight from Florida Keys to Gainesville (average of $359). Flying from Florida Keys to Gainesville in November is currently the most expensive (average of $513). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

Reviews of airlines servicing Gainesville

Get insights into the airlines that provide service to Gainesville. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Gainesville. Reviews last updated September 15, 2025.
Read reviews from past customers who have flown American Airlines from Florida Keys to Gainesville. Users have also rated airlines in terms of entertainment options, comfort, food, crew/service, and boarding process.
American Airlines
7.2
Good
10,000 reviews

Comfort

7.2

Entertainment

6.9

Food

6.4

Overall

7.2

Crew

8.0

Boarding

7.5

Reviews

1 / 20
2.0
Mediocre

Anonymous,Aug 2025

MIA - DCA

Flight delayed 5 hours and was told it was due to mechanical issues. Instead of providing lodging due to missed connecting flight, American changed the cause of delay to weather, which meant they were not able required to provide a hotel. To make matters worse, one of our checked bags was lost even though its status said it was “by the plane” but no one at the service desk seemed able to locate it.
American Airlines
7.2
Good
10,000 reviews
American Airlines
7.2
Good
10,000 reviews

Comfort

7.2

Entertainment

6.9

Food

6.4

Overall

7.2

Crew

8.0

Boarding

7.5

Reviews

1 / 20
2.0
Mediocre

Anonymous,Aug 2025

MIA - DCA

Flight delayed 5 hours and was told it was due to mechanical issues. Instead of providing lodging due to missed connecting flight, American changed the cause of delay to weather, which meant they were not able required to provide a hotel. To make matters worse, one of our checked bags was lost even though its status said it was “by the plane” but no one at the service desk seemed able to locate it.

Related info for your journey

Find useful and relevant information for your journey from Florida Keys to Gainesville. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • What airport do you fly into for flights to Gainesville from Florida Keys?

    Gainesville Regional (GNV) is the airport you will fly into if you book a flight from Florida Keys to Gainesville. It is only a 4.2 mi journey from Gainesville Regional (GNV) to Gainesville’s city center.

  • How long is the flight from Florida Keys to Gainesville?

    American Airlines and Delta can get you from Florida Keys to Gainesville in just under 3h 53m. Your travel time can differ by up to 38m. There are 356 mi between Florida Keys and Gainesville. When browsing for deals, the options you’ll see will be for both nonstop flights and flights with stops.

  • Can I find deals for flights from Florida Keys to Gainesville that include hotel bookings?

    Yes. In addition to deals on Florida Keys to Gainesville flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Florida Keys to Gainesville?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Florida Keys to Gainesville.

  • Can I find deals for business class flights from Florida Keys to Gainesville?

    Yes. Cheapflights offers flight deals from Florida Keys to Gainesville by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Florida Keys to Gainesville?

    Currently, January is the cheapest month in which you can book a flight from Florida Keys to Gainesville (average of $359). Flying from Florida Keys to Gainesville in November is currently the most expensive (average of $513). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

Traveling to a place near Gainesville?

Book flights to Gainesville if you plan to visit one of these locations
Lake City
Alachua

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