HomeSearch by dateVacation packagesHotelsFlight dealsCar rentalTravel tips & news
Florida Keys

$116+ Cheap flights from San Francisco (SFO) to Florida Keys

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 2/18. Fares are subject to change and may not be available on all flights or dates of travel.
SFO — EYW
Feb 20 — Feb 271
Fri 2/20
Fri 2/27
1 adult, Economy
We work with more than 300 partners to bring you better travel deals

Find cheap flights from San Francisco to Florida Keys with Cheapflights

1. Tell us where you want to go

Enter your travel information like dates, passengers, trip type (one-way or round trip), and preferred cabin class then click “Find deals”

2. Select your favorite providers

We find the providers serving your travel needs. Choose up to four travel providers to compare side-by-side for flights, hotels, or car rentals.

3. Compare prices and book

Review each provider’s pricing and select the best option for you! Book through your favorite provider’s website for a seamless experience.

Cheap flight deals from San Francisco to Florida Keys

Cheapest flights from San Francisco to Florida Keys
Explore the most affordable flight options available from San Francisco to Florida Keys. Find the lowest fares from popular airlines and budget airlines, with prices last updated on January 21, 2026.

This American Airlines deal was found by Cheapflights users on 1/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 2/281:20 pm
SFO
-
MIA
Nonstop5h 40m
American Airlines
Wed 3/47:16 am
MIA
-
SFO
Nonstop6h 34m
American Airlines
Deal found 1/20$251
This Kiwi.com deal was found by Cheapflights users on 1/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 3/710:38 pm
SFO
-
MIA
1 stop22h 09m
Frontier
Mon 3/165:05 am
MIA
-
SFO
1 stop17h 09m
Frontier
Deal found 1/20$252
This Kiwi.com deal was found by Cheapflights users on 1/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 3/316:00 am
SFO
-
MIA
1 stop20h 38m
Frontier
Thu 4/212:55 pm
MIA
-
SFO
1 stop9h 19m
Frontier
Deal found 1/20$253
This Kiwi.com deal was found by Cheapflights users on 1/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 2/117:15 pm
SFO
-
MIA
2 stops15h 13m
Multiple Airlines
Tue 2/175:05 am
MIA
-
SFO
1 stop19h 34m
Multiple Airlines
Deal found 1/20$254
This Kiwi.com deal was found by Cheapflights users on 1/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 2/116:55 am
SFO
-
MIA
1 stop19h 19m
Frontier
Wed 2/185:05 am
MIA
-
SFO
1 stop19h 34m
Frontier
Deal found 1/20$255
This Kiwi.com deal was found by Cheapflights users on 1/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 2/1911:09 pm
SFO
-
MIA
1 stop8h 19m
Frontier
Sat 2/215:05 am
MIA
-
SFO
2 stops15h 53m
Frontier
Deal found 1/19$256
This Delta deal was found by Cheapflights users on 1/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 3/317:19 pm
SFO
-
MIA
1 stop7h 21m
Delta
Tue 4/78:05 am
MIA
-
SFO
1 stop9h 58m
Delta
Deal found 1/20$257
This Kiwi.com deal was found by Cheapflights users on 1/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 2/1610:58 pm
SFO
-
MIA
1 stop8h 30m
Frontier
Fri 2/205:05 am
MIA
-
SFO
1 stop19h 34m
Frontier
Deal found 1/20$258
This Kiwi.com deal was found by Cheapflights users on 1/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 3/58:43 am
SFO
-
MIA
2 stops35h 56m
Multiple Airlines
Mon 3/97:05 am
MIA
-
SFO
1 stop15h 09m
Multiple Airlines
Deal found 1/19$259
This American Airlines deal was found by Cheapflights users on 1/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 2/189:14 am
SFO
-
EYW
1 stop10h 08m
American Airlines
Wed 2/253:20 pm
EYW
-
SFO
1 stop10h 00m
American Airlines
Deal found 1/19$259
This Kiwi.com deal was found by Cheapflights users on 1/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 2/2610:46 pm
SFO
-
MIA
1 stop8h 42m
Multiple Airlines
Mon 3/29:53 pm
MIA
-
SFO
2 stops27h 08m
Multiple Airlines
Deal found 1/19$260
This American Airlines deal was found by Cheapflights users on 1/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 2/201:20 pm
SFO
-
MIA
Nonstop5h 40m
American Airlines
Tue 2/248:17 pm
MIA
-
SFO
Nonstop6h 42m
American Airlines
Deal found 1/19$261

Find flight deals from San Francisco to Florida Keys

Keep the following information in mind while searching for San Francisco to Florida Keys flight deals. Data was last updated January 21, 2026.

Most accurate provider

FlightHub
3 stars

Most trusted provider

Expedia
3 stars

Round-trip from

$251
(American Airlines)

One-way from

$116
(Kiwi.com)

Popular in

December

Cheapest in

August

Average price

$357
Provider with most accurate pricing for San Francisco-Miami flight deals.
Search Deals
Provider most trusted by Cheapflights users for San Francisco-Miami flights.
Search Deals
From San Francisco to Florida Keys
Search Deals
One-way flight from San Francisco to Florida Keys
Search Deals
Highest demand for flights based on searches. 8% potential increase in price ($36 potential increase over avg. RT price).
Search Deals
Cheapest flight prices on average. 2% potential price decrease ($10 potential savings vs. average RT price).
Search Deals
Average for round-trip flights in January 2026
Search Deals

Cheapflights Fare Finder

 
Customize your flight search to find flights from San Francisco to Florida Keys that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated January 21, 2026.
Use the filters below to find and compare flights from San Francisco to Florida Keys that are best for you.

Fly from

San Francisco

Fly to

Florida Keys

Route

Depart

Return

Price

San FranciscoMiami

SFO - MIA

SFOMIA

San Francisco

Sat 2/7

2:05 pm-12:51 am

1 stop7h 46m

Miami

Fri 2/13

7:50 am-3:03 pm

1 stop10h 13m

$257

San FranciscoMiami

SFO - MIA

SFOMIA

San Francisco

Sat 2/28

9:10 am-11:20 pm

1 stop11h 10m

Miami

Sat 3/7

7:50 am-3:03 pm

1 stop10h 13m

$257

San FranciscoMiami

SFO - MIA

SFOMIA

San Francisco

Wed 2/4

5:45 am-5:45 pm

1 stop9h 00m

Miami

Fri 2/13

7:50 am-3:03 pm

1 stop10h 13m

$257

San FranciscoKey West

SFO - EYW

SFOEYW

San Francisco

Wed 2/18

9:14 am-10:22 pm

1 stop10h 08m

Key West

Wed 2/25

3:20 pm-10:20 pm

1 stop10h 00m

$259

San FranciscoKey West

SFO - EYW

SFOEYW

San Francisco

Sat 2/21

9:14 am-10:37 pm

1 stop10h 23m

Key West

Wed 2/25

3:20 pm-10:20 pm

1 stop10h 00m

$259

San FranciscoKey West

SFO - EYW

SFOEYW

San Francisco

Sun 2/22

12:30 am-1:15 pm

2 stops9h 45m

Key West

Fri 2/27

4:40 pm-11:10 pm

1 stop9h 30m

$264

San FranciscoMiami

SFO - MIA

SFOMIA

San Francisco

Wed 3/11

5:50 am-5:08 pm

1 stop8h 18m

Miami

Sat 3/14

8:05 am-3:03 pm

1 stop9h 58m

$277

San FranciscoMiami

SFO - MIA

SFOMIA

San Francisco

Sun 5/24

9:15 pm-11:00 am

1 stop10h 45m

Miami

Sat 5/30

9:55 am-6:35 pm

2 stops11h 40m

$293

San FranciscoMiami

SFO - MIA

SFOMIA

San Francisco

Mon 2/23

9:30 pm-4:10 pm

1 stop15h 40m

Miami

Mon 3/2

7:35 am-3:45 pm

1 stop11h 10m

$294

San FranciscoMiami

SFO - MIA

SFOMIA

San Francisco

Sat 2/7

11:18 pm-7:51 am

Nonstop5h 33m

Miami

Tue 2/10

6:05 am-9:43 am

Nonstop6h 38m

$299

Flights are sorted by cheapest round-trip flights first.

Deals found on 1/19

Showing 1-10 of 33 results
1
2
3
4

Best time to book a flight from San Francisco to Florida Keys

Have a flexible travel schedule? Discover the best time to fly to Florida Keys from San Francisco with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from San Francisco to Florida Keys

What is the cheapest month to book a flight from San Francisco to Florida Keys?

Currently, August is the cheapest month in which you can book a flight from San Francisco to Florida Keys (average of $227). Flying from San Francisco to Florida Keys in September is currently the most expensive (average of $501). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

Reviews of airlines servicing Florida Keys

Get insights into the airlines that provide service to Florida Keys. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Florida Keys. Reviews last updated January 21, 2026.
See what other customers who have flown with Delta, United Airlines, and American Airlines from San Francisco to Florida Keys have to say. Users have also rated airlines in terms of entertainment options, comfort, food, crew/service, and boarding process.
Delta
7.9
Good
8,086 reviews

Food

7.2

Crew

8.5

Overall

7.9

Comfort

7.9

Boarding

8.1

Entertainment

7.8

Reviews

1 / 20
2.0
Mediocre

Joseph,Aug 2023

MSP - MCO

Even if you have delta comfort plus, they will move your overhead bag. One of the perks for upgrading is that you have dedicated space for your carry on with comfort plus with delta. They moved my carry on luggage (3) compartments back and put in bags for other passengers that should have gone under their respective seats. When deboarding the plane, there was no help from anyone to retrieve my luggage back several rows. Delta is turning into pure garbage.
Delta
7.9
Good
8,086 reviews
Delta
7.9
Good
8,086 reviews

Food

7.2

Crew

8.5

Overall

7.9

Comfort

7.9

Boarding

8.1

Entertainment

7.8

Reviews

1 / 20
2.0
Mediocre

Joseph,Aug 2023

MSP - MCO

Even if you have delta comfort plus, they will move your overhead bag. One of the perks for upgrading is that you have dedicated space for your carry on with comfort plus with delta. They moved my carry on luggage (3) compartments back and put in bags for other passengers that should have gone under their respective seats. When deboarding the plane, there was no help from anyone to retrieve my luggage back several rows. Delta is turning into pure garbage.
United Airlines
7.4
Good
9,190 reviews
Delta
7.9
Good
8,086 reviews

Food

7.2

Crew

8.5

Overall

7.9

Comfort

7.9

Boarding

8.1

Entertainment

7.8

Reviews

1 / 20
2.0
Mediocre

Joseph,Aug 2023

MSP - MCO

Even if you have delta comfort plus, they will move your overhead bag. One of the perks for upgrading is that you have dedicated space for your carry on with comfort plus with delta. They moved my carry on luggage (3) compartments back and put in bags for other passengers that should have gone under their respective seats. When deboarding the plane, there was no help from anyone to retrieve my luggage back several rows. Delta is turning into pure garbage.
American Airlines
7.2
Good
11,169 reviews
Delta
7.9
Good
8,086 reviews

Food

7.2

Crew

8.5

Overall

7.9

Comfort

7.9

Boarding

8.1

Entertainment

7.8

Reviews

1 / 20
2.0
Mediocre

Joseph,Aug 2023

MSP - MCO

Even if you have delta comfort plus, they will move your overhead bag. One of the perks for upgrading is that you have dedicated space for your carry on with comfort plus with delta. They moved my carry on luggage (3) compartments back and put in bags for other passengers that should have gone under their respective seats. When deboarding the plane, there was no help from anyone to retrieve my luggage back several rows. Delta is turning into pure garbage.
JetBlue
7.2
Good
2,890 reviews
Delta
7.9
Good
8,086 reviews

Food

7.2

Crew

8.5

Overall

7.9

Comfort

7.9

Boarding

8.1

Entertainment

7.8

Reviews

1 / 20
2.0
Mediocre

Joseph,Aug 2023

MSP - MCO

Even if you have delta comfort plus, they will move your overhead bag. One of the perks for upgrading is that you have dedicated space for your carry on with comfort plus with delta. They moved my carry on luggage (3) compartments back and put in bags for other passengers that should have gone under their respective seats. When deboarding the plane, there was no help from anyone to retrieve my luggage back several rows. Delta is turning into pure garbage.
Frontier
5.7
Fair
3,055 reviews
Delta
7.9
Good
8,086 reviews

Food

7.2

Crew

8.5

Overall

7.9

Comfort

7.9

Boarding

8.1

Entertainment

7.8

Reviews

1 / 20
2.0
Mediocre

Joseph,Aug 2023

MSP - MCO

Even if you have delta comfort plus, they will move your overhead bag. One of the perks for upgrading is that you have dedicated space for your carry on with comfort plus with delta. They moved my carry on luggage (3) compartments back and put in bags for other passengers that should have gone under their respective seats. When deboarding the plane, there was no help from anyone to retrieve my luggage back several rows. Delta is turning into pure garbage.

Related info for your journey

Find useful and relevant information for your journey from San Francisco to Florida Keys. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • What airport do you fly from for flights from San Francisco to Florida Keys?

    Located just 11.8 mi from the city center, San Francisco (SFO) is the airport most travelers will use when flying to Florida Keys from San Francisco.

  • How long is the flight from San Francisco to Florida Keys?

    There are many flights that can get you from San Francisco to Florida Keys in 7h 46m. Fly via Delta, American Airlines, or Southwest to get the fastest option. Airlines will cover a distance of 2579 mi. When browsing for deals, the options you’ll see will be for both nonstop flights and flights with stops.

  • What are the cheapest airlines to fly from San Francisco to Florida Keys one-way?

    To fly one-way, consider booking your trip with Frontier, which is currently one of the cheapest options available, starting at $74. Alaska Airlines flights start at $94 while deals on Southwest start at $99 one-way.

  • Can I find deals for flights from San Francisco to Florida Keys that include hotel bookings?

    Yes. In addition to deals on San Francisco to Florida Keys flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from San Francisco to Florida Keys?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from San Francisco to Florida Keys.

  • Can I find deals for business class flights from San Francisco to Florida Keys?

    Yes. Cheapflights offers flight deals from San Francisco to Florida Keys by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from San Francisco to Florida Keys?

    Currently, August is the cheapest month in which you can book a flight from San Francisco to Florida Keys (average of $227). Flying from San Francisco to Florida Keys in September is currently the most expensive (average of $501). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

Browse thousands of different options on Cheapflights for your next trip

Toggle through the tabs below to find thousands of options on Cheapflights for your next trip.

Alternative routes for San Francisco to Florida Keys

See prices for flight routes from nearby airports that may be better suited for you.
Los Angeles to Orlando flights
Los Angeles to Miami flights
Los Angeles to Fort Lauderdale flights
San Francisco to Miami flights
San Francisco to Orlando flights
Los Angeles to Tampa flights
Ontario to Miami flights
San Diego to Orlando flights
Ontario to Orlando flights
San Francisco to Fort Lauderdale flights
Las Vegas to Fort Lauderdale flights
Las Vegas to Orlando flights
San Francisco to Tampa flights
San Diego to Miami flights
Los Angeles to West Palm Beach flights
Sacramento to Orlando flights
Santa Ana to Orlando flights
Las Vegas to Miami flights
Burbank to Fort Lauderdale flights
Ontario to Fort Lauderdale flights
Ontario to Tampa flights
San Diego to Fort Lauderdale flights
San Jose to Miami flights
Santa Ana to Miami flights
San Diego to Tampa flights
San Jose to Orlando flights
Burbank to Orlando flights
Sacramento to Miami flights
Santa Ana to Tampa flights
Santa Ana to Fort Lauderdale flights
Las Vegas to Tampa flights
Los Angeles to Jacksonville flights
San Francisco to West Palm Beach flights
Los Angeles to Sarasota flights
Los Angeles to Fort Myers flights
San Jose to Fort Lauderdale flights
Oakland to Orlando flights
San Francisco to Jacksonville flights
Oakland to Miami flights
Ontario to Sarasota flights
San Francisco to Fort Myers flights
Sacramento to Tampa flights
Fresno to Orlando flights
San Jose to West Palm Beach flights
Los Angeles to Pensacola flights
Ontario to Fort Myers flights
Reno to Orlando flights
Burbank to Miami flights
Sacramento to Fort Lauderdale flights
Palm Springs to Orlando flights

Top 3 airlines flying from San Francisco to Florida Keys

Discover the top 3 airlines that operate flights from San Francisco to Florida Keys. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated January 21, 2026.
AirlineCheapestAverageFlexibilityOn-time
American AirlinesCheapest$256Average$426FlexibilityNo cancel feeOn-time71%
DeltaCheapest$258Average$501FlexibilityNo cancel feeOn-timeN/A
United AirlinesCheapest$390Average$651FlexibilityNo cancel feeOn-time69%

100% Free

Cheapflights is completely free to use, so you can start saving the moment you arrive.

Book with Flexibility

Our users can plan ahead with confidence and find flights with no change fees

Travel Smart

Millions of people come to us for their flight needs every year. We help make travel planning easy by providing useful insights and data-driven graphs that can inform your decisions.