$214+ Cheap flights from Sioux Falls (FSD) to Durham, NC
This is the cheapest round-trip flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 10/12. Fares are subject to change and may not be available on all flights or dates of travel.
FSD — RDU
Oct 13 — Oct 201
Round-trip
1 adult, Economy
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Find cheap flights from Sioux Falls to Durham with Cheapflights
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Enter your travel information like dates, passengers, trip type (one-way or round trip), and preferred cabin class then click “Find deals”2. Select your favorite providers
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Review each provider’s pricing and select the best option for you! Book through your favorite provider’s website for a seamless experience.Cheap flight deals from Sioux Falls to Durham
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Cheapest flights from Sioux Falls to DurhamExplore the most affordable flight options available from Sioux Falls to Durham. Find the lowest fares from popular airlines and budget airlines, with prices last updated on September 13, 2026.
Explore the most affordable flight options available from Sioux Falls to Durham. Find the lowest fares from popular airlines and budget airlines, with prices last updated on September 13, 2026.
This American Airlines deal was found by Cheapflights users on 9/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 10/1012:18 pm -
1 stop6h 27m
Sat 10/176:10 am -
1 stop7h 03m
Deal found 9/10![American Airlines logo]()
$321
This Delta deal was found by Cheapflights users on 9/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 10/65:30 am -
1 stop4h 57m
Sat 10/103:34 pm -
1 stop5h 21m
Deal found 9/10![Delta logo]()
$325
This United Airlines deal was found by Cheapflights users on 9/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 10/107:50 am -
1 stop4h 59m
Sat 10/172:55 pm -
2 stops9h 16m
Deal found 9/10![United Airlines logo]()
$326
This Delta deal was found by Cheapflights users on 9/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 10/35:30 am -
1 stop4h 56m
Tue 10/63:21 pm -
1 stop5h 34m
Deal found 9/10![Delta logo]()
$329
This American Airlines deal was found by Cheapflights users on 9/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 10/62:48 pm -
2 stops8h 09m
Sat 10/109:31 am -
1 stop5h 47m
Deal found 9/10![American Airlines logo]()
$330
This American Airlines deal was found by Cheapflights users on 9/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals ”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 12/91:08 pm -
2 stops9h 21m
Wed 12/1612:07 pm -
2 stops7h 53m
Deal found 9/8![American Airlines logo]()
$331
This American Airlines deal was found by Cheapflights users on 9/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/1612:53 pm -
2 stops8h 40m
Mon 10/198:25 pm -
1 stop5h 16m
Deal found 9/10![American Airlines logo]()
$334
This Delta deal was found by Cheapflights users on 9/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/24:28 pm -
1 stop6h 27m
Wed 10/76:00 am -
1 stop5h 00m
Deal found 9/10![Delta logo]()
$374
This United Airlines deal was found by Cheapflights users on 9/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 9/237:47 am -
1 stop5h 20m
Sat 9/264:27 pm -
1 stop8h 17m
Deal found 9/9![United Airlines logo]()
$379
Best flights from Sioux Falls to DurhamDiscover carefully curated flight deals from Sioux Falls to Durham that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated September 13, 2026.
Discover carefully curated flight deals from Sioux Falls to Durham that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated September 13, 2026.
This American Airlines deal was found by Cheapflights users on 9/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 10/2012:53 pm -
1 stop7h 21m
Sat 10/245:02 am -
2 stops7h 37m
Deal found 9/9![American Airlines logo]()
$326
This Delta deal was found by Cheapflights users on 9/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/24:28 pm -
1 stop6h 27m
Wed 10/76:00 am -
1 stop5h 00m
Deal found 9/10![Delta logo]()
$374
This United Airlines deal was found by Cheapflights users on 9/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 9/237:47 am -
2 stops9h 53m
Sat 9/266:05 am -
1 stop5h 24m
Deal found 9/9![United Airlines logo]()
$384
This American Airlines deal was found by Cheapflights users on 9/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/1612:07 pm -
1 stop6h 34m
Mon 10/198:25 pm -
1 stop5h 16m
Deal found 9/10![American Airlines logo]()
$329
This American Airlines deal was found by Cheapflights users on 9/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 10/62:48 pm -
2 stops8h 09m
Sat 10/102:13 pm -
1 stop8h 00m
Deal found 9/8![American Airlines logo]()
$330
This United Airlines deal was found by Cheapflights users on 9/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/17:50 am -
1 stop4h 59m
Tue 10/64:27 pm -
1 stop8h 17m
Deal found 9/8![United Airlines logo]()
$384
This United Airlines deal was found by Cheapflights users on 9/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 11/67:48 am -
1 stop7h 09m
Mon 11/95:19 pm -
1 stop5h 18m
Deal found 9/8![United Airlines logo]()
$385
This American Airlines deal was found by Cheapflights users on 9/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 10/102:48 pm -
2 stops8h 09m
Sat 10/175:02 am -
2 stops7h 37m
Deal found 9/10![American Airlines logo]()
$387
This American Airlines deal was found by Cheapflights users on 9/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 12/3012:33 pm -
1 stop7h 17m
Wed 1/611:49 am -
1 stop8h 31m
Deal found 9/13![American Airlines logo]()
$388
This United Airlines deal was found by Cheapflights users on 9/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 9/307:50 am -
1 stop7h 13m
Sat 10/34:27 pm -
1 stop8h 17m
Deal found 9/8![United Airlines logo]()
$469
Last-minute flights from Sioux Falls to DurhamDiscover last-minute flight deals from Sioux Falls to Durham. Data last updated September 13, 2026 and is based on user searches.
Discover last-minute flight deals from Sioux Falls to Durham. Data last updated September 13, 2026 and is based on user searches.
This American Airlines deal was found by Cheapflights users on 9/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 9/197:00 am -
1 stop6h 03m
Wed 9/3011:42 am -
1 stop9h 00m
Deal found 9/9![American Airlines logo]()
$381
This United Airlines deal was found by Cheapflights users on 9/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 9/237:47 am -
1 stop5h 20m
Sat 9/264:27 pm -
1 stop8h 17m
Deal found 9/9![United Airlines logo]()
$379
This Delta deal was found by Cheapflights users on 9/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/24:28 pm -
1 stop6h 27m
Wed 10/76:00 am -
1 stop5h 00m
Deal found 9/10![Delta logo]()
$374
This Delta deal was found by Cheapflights users on 9/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 10/35:30 am -
1 stop4h 56m
Tue 10/63:21 pm -
1 stop5h 34m
Deal found 9/10![Delta logo]()
$329
This Delta deal was found by Cheapflights users on 9/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 10/65:30 am -
1 stop4h 57m
Sat 10/103:34 pm -
1 stop5h 21m
Deal found 9/10![Delta logo]()
$325
This American Airlines deal was found by Cheapflights users on 9/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 10/62:48 pm -
2 stops8h 09m
Sat 10/109:31 am -
1 stop5h 47m
Deal found 9/10![American Airlines logo]()
$330
This American Airlines deal was found by Cheapflights users on 9/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 10/1012:18 pm -
1 stop6h 27m
Sat 10/176:10 am -
1 stop7h 03m
Deal found 9/10![American Airlines logo]()
$321
This United Airlines deal was found by Cheapflights users on 9/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 10/107:50 am -
1 stop4h 59m
Sat 10/172:55 pm -
2 stops9h 16m
Deal found 9/10![United Airlines logo]()
$326
This American Airlines deal was found by Cheapflights users on 9/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/1612:53 pm -
2 stops8h 40m
Mon 10/198:25 pm -
1 stop5h 16m
Deal found 9/10![American Airlines logo]()
$334
One-way flights from Sioux Falls to DurhamSearch for one-way flight options from Sioux Falls to Durham. Find affordable one-way fares based on user searches. Data last updated September 13, 2026.
Search for one-way flight options from Sioux Falls to Durham. Find affordable one-way fares based on user searches. Data last updated September 13, 2026.
This Kiwi.com deal was found by Cheapflights users on 9/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 10/128:44 pm -
2 stops35h 23m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 9/11![Multiple Airlines logo]()
$214
This Kiwi.com deal was found by Cheapflights users on 9/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 11/206:38 pm -
1 stop24h 52m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 9/8![Multiple Airlines logo]()
$292
This United Airlines deal was found by Cheapflights users on 9/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 10/61:46 pm -
1 stop6h 53m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 9/9![United Airlines logo]()
$309
This United Airlines deal was found by Cheapflights users on 9/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 10/127:50 am -
1 stop7h 13m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 9/11![United Airlines logo]()
$319
This American Airlines deal was found by Cheapflights users on 9/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 11/201:13 pm -
2 stops9h 46m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 9/8![American Airlines logo]()
$334
This Kiwi.com deal was found by Cheapflights users on 9/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/98:52 pm -
2 stops35h 28m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 9/9![Multiple Airlines logo]()
$341
This Delta deal was found by Cheapflights users on 9/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 1/28:00 am -
1 stop7h 18m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 9/9![Delta logo]()
$402
This Kiwi.com deal was found by Cheapflights users on 9/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 1/210:06 am -
2 stops13h 36m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 9/9![Multiple Airlines logo]()
$407
Find flight deals from Sioux Falls to Durham
Keep the following information in mind while searching for Sioux Falls to Durham flight deals. Data was last updated September 13, 2026.
Most accurate provider | FlightHub 3 stars |
|---|---|
Most trusted provider | FlightHub 3 stars |
Round-trip from | $321 (American Airlines) |
One-way from | $214 (Kiwi.com) |
Popular in | June |
Cheapest in | October |
Average price | $358 |
Cheapflights Fare Finder
Customize your flight search to find flights from Sioux Falls to Durham that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 7,457,451 searches. Data last updated September 13, 2026.
Use the filters below to find and compare flights from Sioux Falls to Durham that are best for you.
Fly from
Fly to
Route
Depart
Return
Cheapest round-trip
Sioux FallsRaleigh
FSD Sioux Falls Joe Foss Field - RDU Raleigh-Durham
FSDRDU
Sioux Falls Joe Foss Field
Mon 10/12
8:44 pm-8:59 am
3 stops35h 15m
Raleigh-Durham
Wed 12/31
12:00 am-11:00 pm
Nonstop0h 00m
$289
Sioux FallsRaleigh
FSD Sioux Falls Joe Foss Field - RDU Raleigh-Durham
FSDRDU
Sioux Falls Joe Foss Field
Fri 11/20
6:38 pm-8:30 pm
1 stop24h 52m
Raleigh-Durham
Wed 12/31
12:00 am-11:00 pm
Nonstop0h 00m
$292
Sioux FallsRaleigh
FSD Sioux Falls Joe Foss Field - RDU Raleigh-Durham
FSDRDU
Sioux Falls Joe Foss Field
Tue 10/6
1:46 pm-9:39 pm
1 stop6h 53m
Raleigh-Durham
Wed 12/31
12:00 am-11:00 pm
Nonstop0h 00m
$309
Quickest round-trip
Sioux FallsRaleigh
FSD Sioux Falls Joe Foss Field - RDU Raleigh-Durham
FSDRDU
Sioux Falls Joe Foss Field
Fri 10/9
7:50 am-1:49 pm
1 stop4h 59m
Raleigh-Durham
Wed 12/31
12:00 am-11:00 pm
Nonstop0h 00m
$309
Sioux FallsRaleigh
FSD Sioux Falls Joe Foss Field - RDU Raleigh-Durham
FSDRDU
Sioux Falls Joe Foss Field
Mon 10/12
7:50 am-4:03 pm
1 stop7h 13m
Raleigh-Durham
Wed 12/31
12:00 am-11:00 pm
Nonstop0h 00m
$319
Sioux FallsRaleigh
FSD Sioux Falls Joe Foss Field - RDU Raleigh-Durham
FSDRDU
Sioux Falls Joe Foss Field
Tue 10/20
12:53 pm-9:14 pm
1 stop7h 21m
Raleigh-Durham
Sat 10/24
5:02 am-11:39 am
2 stops7h 37m
$326
Sioux FallsRaleigh
FSD Sioux Falls Joe Foss Field - RDU Raleigh-Durham
FSDRDU
Sioux Falls Joe Foss Field
Fri 10/16
12:07 pm-7:41 pm
1 stop6h 34m
Raleigh-Durham
Mon 10/19
8:25 pm-12:41 am
1 stop5h 16m
$329
Sioux FallsRaleigh
FSD Sioux Falls Joe Foss Field - RDU Raleigh-Durham
FSDRDU
Sioux Falls Joe Foss Field
Tue 10/6
2:48 pm-11:57 pm
2 stops8h 09m
Raleigh-Durham
Sat 10/10
2:13 pm-9:13 pm
1 stop8h 00m
$330
Sioux FallsRaleigh
FSD Sioux Falls Joe Foss Field - RDU Raleigh-Durham
FSDRDU
Sioux Falls Joe Foss Field
Fri 11/20
1:13 pm-11:59 pm
2 stops9h 46m
Raleigh-Durham
Wed 12/31
12:00 am-11:00 pm
Nonstop0h 00m
$334
Sioux FallsRaleigh
FSD Sioux Falls Joe Foss Field - RDU Raleigh-Durham
FSDRDU
Sioux Falls Joe Foss Field
Fri 10/9
8:52 pm-9:20 am
2 stops35h 28m
Raleigh-Durham
Wed 12/31
12:00 am-11:00 pm
Nonstop0h 00m
$341
Showing 1-10 of 19 resultsSorted by cheapest first
Best time to book a flight from Sioux Falls to Durham
Have a flexible travel schedule? Discover the best time to fly to Durham from Sioux Falls with our price prediction graph.
FSD-RDU
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.
Cheapflights Insights
Everything you need to know about your flight from Sioux Falls to Durham
FSD-DU8
FSD-RDU
How much does it cost to fly round-trip from Sioux Falls to Durham?
Airfare is typical for this route at the moment.
Sioux Falls to Durham flights typically cost between $302 and $448 in October.The cheapest round-trip price found within the last 5 days was $321 on American Airlines (Oct 10-Oct 17).
Reviews of airlines servicing Durham
Get insights into the airlines that provide service to Durham. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Durham. Reviews last updated September 13, 2026.
See what other customers who have flown with Delta,United Airlines, andAmerican Airlines from Sioux Falls to Durham have to say. You can also see how each airline compares in terms of entertainment options, comfort, food, crew/service, and boarding process.
Boarding
8.1
Comfort
7.8
Entertainment
7.8
Overall
7.8
Food
7.2
Crew
8.5
Reviews
1 / 20
4.0
OkayJennifer,Sep 2026
ORD - LGA
Boarding
8.1
Comfort
7.8
Entertainment
7.8
Overall
7.8
Food
7.2
Crew
8.5
Reviews
1 / 20
4.0
OkayJennifer,Sep 2026
ORD - LGA
Boarding
8.1
Comfort
7.8
Entertainment
7.8
Overall
7.8
Food
7.2
Crew
8.5
Reviews
1 / 20
4.0
OkayJennifer,Sep 2026
ORD - LGA
Boarding
8.1
Comfort
7.8
Entertainment
7.8
Overall
7.8
Food
7.2
Crew
8.5
Reviews
1 / 20
4.0
OkayJennifer,Sep 2026
ORD - LGA
Related info for your journey
Find useful and relevant information for your journey from Sioux Falls to Durham. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.
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Complete your trip
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Find flights from Sioux Falls to Durham, based on your preferred cabin class, be it economy, premium economy, business, or first class.
Sioux Falls and Durham flights
Browse other Sioux Falls and Durham flight options. Last updated on September 13, 2026.
Other flights from Sioux Falls
Browse through other flights departing from Sioux Falls. Flights are based on user searches made on Cheapflights and were last updated on September 13, 2026.
Popular flight searches
Check out other popular destinations found by fellow travelers in 2026
Sioux Falls to Durham flights
Consider these flights traveling from Sioux Falls to Durham.
Top 3 airlines flying from Sioux Falls to Durham
Discover the top 3 airlines that operate flights from Sioux Falls to Durham. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 7,457,451 searches. Data last updated September 13, 2026.
| Airline | Cheapest | Average | Flexibility | On-time |
|---|---|---|---|---|
| Cheapest$258 | Average$311 | FlexibilityNo cancel fee | On-time71% | |
| Cheapest$299 | Average$412 | FlexibilityNo cancel fee | On-timeN/A | |
| Cheapest$307 | Average$511 | FlexibilityNo cancel fee | On-time69% |