$145+ Cheap flights from Sioux Falls (FSD) to Durham, NC
This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 7/20. Fares are subject to change and may not be available on all flights or dates of travel.
FSD — RDU
jul. 6 — jul. 131
Round-trip
1 adult, Economy
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Find cheap flights from Sioux Falls to Durham with Cheapflights
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Enter your travel information like dates, passengers, trip type (one-way or round trip), and preferred cabin class then click “Find deals”2. Select your favorite providers
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Review each provider’s pricing and select the best option for you! Book through your favorite provider’s website for a seamless experience.Cheap flight deals from Sioux Falls to Durham
Cheapest
Best
Last-minute
One-way
Cheapest flights from Sioux Falls to DurhamExplore the most affordable flight options available from Sioux Falls to Durham. Find the lowest fares from popular airlines and budget airlines, with prices last updated on juni 6, 2026.
Explore the most affordable flight options available from Sioux Falls to Durham. Find the lowest fares from popular airlines and budget airlines, with prices last updated on juni 6, 2026.
This American Airlines deal was found by Cheapflights users on 6/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
wo 9/96:00 am
FSD
- RDU
1 stop9h 05m
American Airlines
za 9/122:18 pm
RDU
- FSD
1 stop7h 26m
American Airlines
Deal found 6/5![American Airlines logo]()
$311
This American Airlines deal was found by Cheapflights users on 6/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
vr 7/36:00 am
FSD
- RDU
1 stop6h 27m
American Airlines
wo 7/87:14 pm
RDU
- FSD
1 stop6h 04m
American Airlines
Deal found 6/1![American Airlines logo]()
$315
This American Airlines deal was found by Cheapflights users on 6/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
di 6/166:00 am
FSD
- RDU
1 stop6h 28m
American Airlines
di 6/236:08 pm
RDU
- FSD
1 stop7h 12m
American Airlines
Deal found 6/1![American Airlines logo]()
$344
This Delta deal was found by Cheapflights users on 6/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
vr 7/35:12 am
FSD
- RDU
1 stop4h 21m
Delta
wo 7/87:10 pm
RDU
- FSD
1 stop4h 56m
Delta
Deal found 6/2![Delta logo]()
$345
This American Airlines deal was found by Cheapflights users on 6/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
do 6/186:00 am
FSD
- RDU
1 stop6h 28m
American Airlines
ma 6/227:09 pm
RDU
- FSD
1 stop6h 11m
American Airlines
Deal found 6/3![American Airlines logo]()
$369
This Expedia deal was found by Cheapflights users on 6/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Expedia is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
wo 6/108:14 pm
FSD
- RDU
1 stop14h 17m
Frontier
wo 6/1712:26 pm
RDU
- FSD
1 stop7h 53m
Frontier
Deal found 6/4![Frontier logo]()
$390
Best flights from Sioux Falls to DurhamDiscover carefully curated flight deals from Sioux Falls to Durham that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated juni 6, 2026.
Discover carefully curated flight deals from Sioux Falls to Durham that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated juni 6, 2026.
This Delta deal was found by Cheapflights users on 6/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
di 10/65:15 am
FSD
- RDU
1 stop4h 22m
Delta
za 10/106:00 am
RDU
- FSD
1 stop7h 11m
Delta
Deal found 6/3![Delta logo]()
$311
This American Airlines deal was found by Cheapflights users on 6/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
wo 9/912:56 pm
FSD
- RDU
2 stops9h 01m
American Airlines
za 9/1210:30 am
RDU
- FSD
2 stops8h 41m
American Airlines
Deal found 6/5![American Airlines logo]()
$321
This United Airlines deal was found by Cheapflights users on 6/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
za 8/297:47 am
FSD
- RDU
1 stop5h 30m
United Airlines
di 9/14:23 pm
RDU
- FSD
1 stop8h 21m
United Airlines
Deal found 6/1![United Airlines logo]()
$401
This Delta deal was found by Cheapflights users on 6/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
vr 7/35:12 am
FSD
- RDU
1 stop4h 21m
Delta
wo 7/87:10 pm
RDU
- FSD
1 stop4h 56m
Delta
Deal found 6/2![Delta logo]()
$345
This American Airlines deal was found by Cheapflights users on 6/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
do 6/186:00 am
FSD
- RDU
1 stop6h 28m
American Airlines
za 6/207:03 am
RDU
- FSD
1 stop5h 36m
American Airlines
Deal found 6/2![American Airlines logo]()
$369
Last-minute flights from Sioux Falls to DurhamDiscover last-minute flight deals from Sioux Falls to Durham. Data last updated juni 6, 2026 and is based on user searches.
Discover last-minute flight deals from Sioux Falls to Durham. Data last updated juni 6, 2026 and is based on user searches.
This Gotogate deal was found by Cheapflights users on 6/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Gotogate is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
vr 6/54:25 pm
FSD
- RDU
1 stop18h 06m
Frontier
vr 6/1212:26 pm
RDU
- FSD
1 stop7h 53m
Frontier
Deal found 6/4![Frontier logo]()
$399
This American Airlines deal was found by Cheapflights users on 6/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
za 6/612:18 pm
FSD
- RDU
1 stop6h 08m
American Airlines
di 6/96:08 pm
RDU
- FSD
1 stop7h 12m
American Airlines
Deal found 6/4![American Airlines logo]()
$423
This Expedia deal was found by Cheapflights users on 6/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Expedia is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
wo 6/108:14 pm
FSD
- RDU
1 stop14h 17m
Frontier
wo 6/1712:26 pm
RDU
- FSD
1 stop7h 53m
Frontier
Deal found 6/4![Frontier logo]()
$390
This American Airlines deal was found by Cheapflights users on 6/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
di 6/166:00 am
FSD
- RDU
1 stop6h 28m
American Airlines
di 6/236:08 pm
RDU
- FSD
1 stop7h 12m
American Airlines
Deal found 6/1![American Airlines logo]()
$344
This American Airlines deal was found by Cheapflights users on 6/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
do 6/186:00 am
FSD
- RDU
1 stop6h 28m
American Airlines
ma 6/227:09 pm
RDU
- FSD
1 stop6h 11m
American Airlines
Deal found 6/3![American Airlines logo]()
$369
This American Airlines deal was found by Cheapflights users on 6/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
vr 6/264:40 pm
FSD
- RDU
1 stop6h 10m
American Airlines
di 6/305:20 am
RDU
- FSD
1 stop7h 52m
American Airlines
Deal found 6/4![American Airlines logo]()
$422
This American Airlines deal was found by Cheapflights users on 6/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
vr 7/36:00 am
FSD
- RDU
1 stop6h 27m
American Airlines
wo 7/87:14 pm
RDU
- FSD
1 stop6h 04m
American Airlines
Deal found 6/1![American Airlines logo]()
$315
This Delta deal was found by Cheapflights users on 6/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
vr 7/35:12 am
FSD
- RDU
1 stop4h 21m
Delta
wo 7/87:10 pm
RDU
- FSD
1 stop4h 56m
Delta
Deal found 6/2![Delta logo]()
$345
One-way flights from Sioux Falls to DurhamSearch for one-way flight options from Sioux Falls to Durham. Find affordable one-way fares based on user searches. Data last updated juni 6, 2026.
Search for one-way flight options from Sioux Falls to Durham. Find affordable one-way fares based on user searches. Data last updated juni 6, 2026.
This Gotogate deal was found by Cheapflights users on 6/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Gotogate is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
ma 7/208:08 pm
FSD
- RDU
1 stop14h 23m
Frontier
Deal found 6/5![Frontier logo]()
$145
This Expedia deal was found by Cheapflights users on 6/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Expedia is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
wo 7/88:08 pm
FSD
- RDU
1 stop14h 23m
Frontier
Deal found 6/1![Frontier logo]()
$185
This Kiwi.com deal was found by Cheapflights users on 6/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
zo 7/56:36 pm
FSD
- RDU
3 stops50h 13m
Multiple Airlines
Deal found 6/2![Multiple Airlines logo]()
$259
This KAYAK deal was found by Cheapflights users on 6/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure KAYAK is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
vr 6/1211:16 am
FSD
- RDU
1 stop5h 11m
United Airlines
Deal found 6/3![United Airlines logo]()
$417
This United Airlines deal was found by Cheapflights users on 6/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
zo 7/57:35 am
FSD
- RDU
1 stop5h 26m
United Airlines
Deal found 6/2![United Airlines logo]()
$432
This Kiwi.com deal was found by Cheapflights users on 6/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
wo 7/88:53 pm
FSD
- RDU
3 stops35h 06m
Multiple Airlines
Deal found 6/1![Multiple Airlines logo]()
$471
This American Airlines deal was found by Cheapflights users on 6/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
zo 7/57:06 am
FSD
- RDU
2 stops7h 07m
American Airlines
Deal found 6/2![American Airlines logo]()
$662
This Delta deal was found by Cheapflights users on 6/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
ma 7/205:00 am
FSD
- RDU
2 stops9h 04m
Delta
Deal found 6/5![Delta logo]()
$927
Find flight deals from Sioux Falls to Durham
Keep the following information in mind while searching for Sioux Falls to Durham flight deals. Data was last updated juni 6, 2026.
Most accurate provider | FlightHub 3 stars |
|---|---|
Most trusted provider | FlightHub 3 stars |
Round-trip from | $311 (American Airlines) |
One-way from | $145 (Gotogate) |
Popular in | March |
Cheapest in | August |
Average price | $406 |
Cheapflights Fare Finder
Customize your flight search to find flights from Sioux Falls to Durham that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated juni 6, 2026.
Use the filters below to find and compare flights from Sioux Falls to Durham that are best for you.
Fly from
Fly to
Route
Depart
Return
Cheapest round-trip
Sioux FallsRaleigh
FSD - RDU
FSDRDU
Sioux Falls Joe Foss Field
di 10/6
5:15 am-10:37 am
1 stop4h 22m
Raleigh-Durham
za 10/10
6:00 am-12:11 pm
1 stop7h 11m
$311
Sioux FallsRaleigh
FSD - RDU
FSDRDU
Sioux Falls Joe Foss Field
wo 9/9
12:56 pm-10:57 pm
2 stops9h 01m
Raleigh-Durham
za 9/12
10:30 am-6:11 pm
2 stops8h 41m
$321
Quickest round-trip
Sioux FallsRaleigh
FSD - RDU
FSDRDU
Sioux Falls Joe Foss Field
vr 7/3
5:12 am-10:33 am
1 stop4h 21m
Raleigh-Durham
wo 7/8
7:10 pm-11:06 pm
1 stop4h 56m
$345
Sioux FallsRaleigh
FSD - RDU
FSDRDU
Sioux Falls Joe Foss Field
do 6/18
6:00 am-1:28 pm
1 stop6h 28m
Raleigh-Durham
za 6/20
7:03 am-11:39 am
1 stop5h 36m
$369
Sioux FallsRaleigh
FSD - RDU
FSDRDU
Sioux Falls Joe Foss Field
za 8/29
7:47 am-2:17 pm
1 stop5h 30m
Raleigh-Durham
di 9/1
4:23 pm-11:44 pm
1 stop8h 21m
$401
Cheapest one-way
Sioux FallsRaleigh
FSD - RDU
FSDRDU
Sioux Falls Joe Foss Field
ma 7/20
8:08 pm-11:31 am
1 stop14h 23m
$145
Sioux FallsRaleigh
FSD - RDU
FSDRDU
Sioux Falls Joe Foss Field
wo 7/8
8:08 pm-11:31 am
1 stop14h 23m
$185
Quickest one-way
Sioux FallsRaleigh
FSD - RDU
FSDRDU
Sioux Falls Joe Foss Field
vr 6/12
11:16 am-5:27 pm
1 stop5h 11m
$417
Sioux FallsRaleigh
FSD - RDU
FSDRDU
Sioux Falls Joe Foss Field
zo 7/5
7:35 am-2:01 pm
1 stop5h 26m
$432
Sioux FallsRaleigh
FSD - RDU
FSDRDU
Sioux Falls Joe Foss Field
wo 7/8
8:53 pm-8:59 am
3 stops35h 06m
$471
Showing 1-10 of 12 resultsSorted by cheapest first
Best time to book a flight from Sioux Falls to Durham
Have a flexible travel schedule? Discover the best time to fly to Durham from Sioux Falls with our price prediction graph.
FSD-RDU
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.
Cheapflights Insights
Everything you need to know about your flight from Sioux Falls to Durham
FSD-DU8
FSD-RDU
How much does it cost to fly round-trip from Sioux Falls to Durham?
Reviews of airlines servicing Durham
Get insights into the airlines that provide service to Durham. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Durham. Reviews last updated juni 6, 2026.
See what other customers who have flown with Delta,United Airlines, andAmerican Airlines from Sioux Falls to Durham have to say. You can also see how each airline compares in terms of entertainment options, comfort, food, crew/service, and boarding process.
Boarding
8.1
Crew
8.5
Overall
7.9
Entertainment
7.8
Food
7.2
Comfort
7.8
Reviews
1 / 20
10.0
ExcellentAnonymous,May 2026
SEA - KOA
Boarding
8.1
Crew
8.5
Overall
7.9
Entertainment
7.8
Food
7.2
Comfort
7.8
Reviews
1 / 20
10.0
ExcellentAnonymous,May 2026
SEA - KOA
Boarding
8.1
Crew
8.5
Overall
7.9
Entertainment
7.8
Food
7.2
Comfort
7.8
Reviews
1 / 20
10.0
ExcellentAnonymous,May 2026
SEA - KOA
Boarding
8.1
Crew
8.5
Overall
7.9
Entertainment
7.8
Food
7.2
Comfort
7.8
Reviews
1 / 20
10.0
ExcellentAnonymous,May 2026
SEA - KOA
Related info for your journey
Find useful and relevant information for your journey from Sioux Falls to Durham. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.
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Sioux Falls and Durham flights
Browse other Sioux Falls and Durham flight options. Last updated on juni 6, 2026.
Other flights from Sioux Falls
Browse through other flights departing from Sioux Falls. Flights are based on user searches made on Cheapflights and were last updated on juni 6, 2026.
Popular flight searches
Check out other popular destinations found by fellow travelers in 2026
Sioux Falls to Durham flights
Consider these flights traveling from Sioux Falls to Durham.
Top 3 airlines flying from Sioux Falls to Durham
Discover the top 3 airlines that operate flights from Sioux Falls to Durham. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated juni 6, 2026.
| Airline | Cheapest | Average | Flexibility | On-time |
|---|---|---|---|---|
| Cheapest$258 | Average$366 | FlexibilityNo cancel fee | On-time71% | |
| Cheapest$258 | Average$355 | FlexibilityNo cancel fee | On-timeN/A | |
| Cheapest$307 | Average$473 | FlexibilityNo cancel fee | On-time69% |