$135+ Cheap flights from Sioux Falls (FSD) to Durham, NC
This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 7/1. Fares are subject to change and may not be available on all flights or dates of travel.
FSD — RDU
Jul 19 — Jul 261
Round-trip
1 adult, Economy
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Find cheap flights from Sioux Falls to Durham with Cheapflights
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Enter your travel information like dates, passengers, trip type (one-way or round trip), and preferred cabin class then click “Find deals”2. Select your favorite providers
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Best
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Cheapest flights from Sioux Falls to DurhamExplore the most affordable flight options available from Sioux Falls to Durham. Find the lowest fares from popular airlines and budget airlines, with prices last updated on June 19, 2026.
Explore the most affordable flight options available from Sioux Falls to Durham. Find the lowest fares from popular airlines and budget airlines, with prices last updated on June 19, 2026.
This American Airlines deal was found by Cheapflights users on 6/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 9/96:00 am
FSD
- RDU
1 stop9h 05m
American Airlines
Sat 9/126:00 am
RDU
- FSD
1 stop6h 41m
American Airlines
Deal found 6/19![American Airlines logo]()
$311
This Delta deal was found by Cheapflights users on 6/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 7/34:26 pm
FSD
- RDU
1 stop6h 33m
Delta
Wed 7/86:00 am
RDU
- FSD
1 stop7h 49m
Delta
Deal found 6/16![Delta logo]()
$315
This Delta deal was found by Cheapflights users on 6/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 10/65:15 am
FSD
- RDU
1 stop4h 22m
Delta
Sat 10/106:00 am
RDU
- FSD
1 stop7h 11m
Delta
Deal found 6/18![Delta logo]()
$319
This American Airlines deal was found by Cheapflights users on 6/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 7/34:43 pm
FSD
- RDU
1 stop6h 19m
American Airlines
Wed 7/83:07 pm
RDU
- FSD
2 stops10h 11m
American Airlines
Deal found 6/16![American Airlines logo]()
$320
This Delta deal was found by Cheapflights users on 6/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 8/265:30 am
FSD
- RDU
1 stop6h 15m
Delta
Sun 8/306:00 am
RDU
- FSD
1 stop5h 20m
Delta
Deal found 6/18![Delta logo]()
$329
This Expedia deal was found by Cheapflights users on 6/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Expedia is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 10/57:31 pm
FSD
- RDU
1 stop15h 22m
Frontier
Sat 10/1012:18 pm
RDU
- FSD
1 stop7h 18m
Frontier
Deal found 6/15![Frontier logo]()
$344
Best flights from Sioux Falls to DurhamDiscover carefully curated flight deals from Sioux Falls to Durham that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated June 19, 2026.
Discover carefully curated flight deals from Sioux Falls to Durham that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated June 19, 2026.
This American Airlines deal was found by Cheapflights users on 6/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 8/126:24 am
FSD
- RDU
1 stop5h 24m
American Airlines
Sat 8/157:04 am
RDU
- FSD
1 stop5h 32m
American Airlines
Deal found 6/14![American Airlines logo]()
$311
This Delta deal was found by Cheapflights users on 6/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 10/65:25 am
FSD
- RDU
1 stop7h 42m
Delta
Sat 10/106:00 am
RDU
- FSD
1 stop5h 05m
Delta
Deal found 6/17![Delta logo]()
$311
This United Airlines deal was found by Cheapflights users on 6/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 8/297:47 am
FSD
- RDU
1 stop5h 30m
United Airlines
Wed 9/211:29 am
RDU
- FSD
1 stop7h 29m
United Airlines
Deal found 6/16![United Airlines logo]()
$401
This Delta deal was found by Cheapflights users on 6/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 12/165:15 am
FSD
- RDU
1 stop4h 22m
Delta
Sun 12/206:00 am
RDU
- FSD
1 stop7h 11m
Delta
Deal found 6/17![Delta logo]()
$315
This American Airlines deal was found by Cheapflights users on 6/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 7/34:43 pm
FSD
- RDU
1 stop6h 19m
American Airlines
Wed 7/83:07 pm
RDU
- FSD
2 stops10h 11m
American Airlines
Deal found 6/16![American Airlines logo]()
$320
Last-minute flights from Sioux Falls to DurhamDiscover last-minute flight deals from Sioux Falls to Durham. Data last updated June 19, 2026 and is based on user searches.
Discover last-minute flight deals from Sioux Falls to Durham. Data last updated June 19, 2026 and is based on user searches.
This Delta deal was found by Cheapflights users on 6/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 6/2410:56 am
FSD
- RDU
1 stop5h 58m
Delta
Sun 6/286:00 am
RDU
- FSD
1 stop5h 16m
Delta
Deal found 6/15![Delta logo]()
$441
This Delta deal was found by Cheapflights users on 6/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 7/34:26 pm
FSD
- RDU
1 stop6h 33m
Delta
Wed 7/86:00 am
RDU
- FSD
1 stop7h 49m
Delta
Deal found 6/16![Delta logo]()
$315
This American Airlines deal was found by Cheapflights users on 6/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 7/34:43 pm
FSD
- RDU
1 stop6h 19m
American Airlines
Wed 7/83:07 pm
RDU
- FSD
2 stops10h 11m
American Airlines
Deal found 6/16![American Airlines logo]()
$320
This Delta deal was found by Cheapflights users on 6/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 7/225:00 am
FSD
- RDU
1 stop4h 31m
Delta
Sun 7/266:00 am
RDU
- FSD
1 stop5h 15m
Delta
Deal found 6/15![Delta logo]()
$399
This American Airlines deal was found by Cheapflights users on 6/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 7/226:00 am
FSD
- RDU
2 stops8h 25m
American Airlines
Sun 7/267:08 am
RDU
- FSD
1 stop5h 22m
American Airlines
Deal found 6/19![American Airlines logo]()
$427
One-way flights from Sioux Falls to DurhamSearch for one-way flight options from Sioux Falls to Durham. Find affordable one-way fares based on user searches. Data last updated June 19, 2026.
Search for one-way flight options from Sioux Falls to Durham. Find affordable one-way fares based on user searches. Data last updated June 19, 2026.
This Trip.com deal was found by Cheapflights users on 6/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Trip.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 7/18:14 pm
FSD
- RDU
1 stop14h 17m
Frontier
Deal found 6/19![Frontier logo]()
$135
This Expedia deal was found by Cheapflights users on 6/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Expedia is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 7/64:40 pm
FSD
- RDU
1 stop17h 51m
Frontier
Deal found 6/18![Frontier logo]()
$151
This Kiwi.com deal was found by Cheapflights users on 6/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 7/11:06 pm
FSD
- RDU
2 stops47h 13m
Multiple Airlines
Deal found 6/19![Multiple Airlines logo]()
$292
This American Airlines deal was found by Cheapflights users on 6/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 12/151:09 pm
FSD
- RDU
1 stop7h 58m
American Airlines
Deal found 6/16![American Airlines logo]()
$304
This United Airlines deal was found by Cheapflights users on 6/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 12/153:16 pm
FSD
- RDU
2 stops7h 17m
United Airlines
Deal found 6/16![United Airlines logo]()
$309
This United Airlines deal was found by Cheapflights users on 6/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 7/67:35 am
FSD
- RDU
1 stop5h 26m
United Airlines
Deal found 6/16![United Airlines logo]()
$448
This American Airlines deal was found by Cheapflights users on 6/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 7/67:06 am
FSD
- RDU
2 stops9h 19m
American Airlines
Deal found 6/18![American Airlines logo]()
$671
Find flight deals from Sioux Falls to Durham
Keep the following information in mind while searching for Sioux Falls to Durham flight deals. Data was last updated June 19, 2026.
Most accurate provider | FlightHub 3 stars |
|---|---|
Most trusted provider | FlightHub 3 stars |
Round-trip from | $311 (American Airlines) |
One-way from | $151 (Expedia) |
Popular in | June |
Cheapest in | August |
Average price | $626 |
Cheapflights Fare Finder
Customize your flight search to find flights from Sioux Falls to Durham that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated June 19, 2026.
Use the filters below to find and compare flights from Sioux Falls to Durham that are best for you.
Fly from
Fly to
Route
Depart
Return
Cheapest round-trip
Quickest round-trip
Sioux FallsRaleigh
FSD - RDU
FSDRDU
Sioux Falls Joe Foss Field
Wed 8/12
6:24 am-12:48 pm
1 stop5h 24m
Raleigh-Durham
Sat 8/15
7:04 am-11:36 am
1 stop5h 32m
$311
Sioux FallsRaleigh
FSD - RDU
FSDRDU
Sioux Falls Joe Foss Field
Tue 10/6
5:25 am-2:07 pm
1 stop7h 42m
Raleigh-Durham
Sat 10/10
6:00 am-10:05 am
1 stop5h 05m
$311
Sioux FallsRaleigh
FSD - RDU
FSDRDU
Sioux Falls Joe Foss Field
Wed 12/16
5:15 am-10:37 am
1 stop4h 22m
Raleigh-Durham
Sun 12/20
6:00 am-12:11 pm
1 stop7h 11m
$315
Sioux FallsRaleigh
FSD - RDU
FSDRDU
Sioux Falls Joe Foss Field
Fri 7/3
4:43 pm-12:02 am
1 stop6h 19m
Raleigh-Durham
Wed 7/8
3:07 pm-12:18 am
2 stops10h 11m
$320
Sioux FallsRaleigh
FSD - RDU
FSDRDU
Sioux Falls Joe Foss Field
Sat 8/29
7:47 am-2:17 pm
1 stop5h 30m
Raleigh-Durham
Wed 9/2
11:29 am-5:58 pm
1 stop7h 29m
$401
Cheapest one-way
Sioux FallsRaleigh
FSD - RDU
FSDRDU
Sioux Falls Joe Foss Field
Wed 7/1
8:14 pm-11:31 am
1 stop14h 17m
$135
Sioux FallsRaleigh
FSD - RDU
FSDRDU
Sioux Falls Joe Foss Field
Mon 7/6
4:40 pm-11:31 am
1 stop17h 51m
$151
Sioux FallsRaleigh
FSD - RDU
FSDRDU
Sioux Falls Joe Foss Field
Tue 12/15
1:09 pm-10:07 pm
1 stop7h 58m
$304
Sioux FallsRaleigh
FSD - RDU
FSDRDU
Sioux Falls Joe Foss Field
Tue 12/15
3:16 pm-11:33 pm
2 stops7h 17m
$309
Quickest one-way
Sioux FallsRaleigh
FSD - RDU
FSDRDU
Sioux Falls Joe Foss Field
Mon 7/6
7:35 am-2:01 pm
1 stop5h 26m
$448
Showing 1-10 of 11 resultsSorted by cheapest first
Best time to book a flight from Sioux Falls to Durham
Have a flexible travel schedule? Discover the best time to fly to Durham from Sioux Falls with our price prediction graph.
FSD-RDU
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.
Cheapflights Insights
Everything you need to know about your flight from Sioux Falls to Durham
FSD-DU8
FSD-RDU
How much does it cost to fly round-trip from Sioux Falls to Durham?
Reviews of airlines servicing Durham
Get insights into the airlines that provide service to Durham. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Durham. Reviews last updated June 19, 2026.
See what other customers who have flown with Delta,United Airlines, andAmerican Airlines from Sioux Falls to Durham have to say. You can also see how each airline compares in terms of entertainment options, comfort, food, crew/service, and boarding process.
Comfort
7.8
Food
7.2
Crew
8.5
Overall
7.8
Boarding
8.1
Entertainment
7.8
Reviews
1 / 20
10.0
ExcellentAnonymous,May 2026
SEA - KOA
Comfort
7.8
Food
7.2
Crew
8.5
Overall
7.8
Boarding
8.1
Entertainment
7.8
Reviews
1 / 20
10.0
ExcellentAnonymous,May 2026
SEA - KOA
Comfort
7.8
Food
7.2
Crew
8.5
Overall
7.8
Boarding
8.1
Entertainment
7.8
Reviews
1 / 20
10.0
ExcellentAnonymous,May 2026
SEA - KOA
Comfort
7.8
Food
7.2
Crew
8.5
Overall
7.8
Boarding
8.1
Entertainment
7.8
Reviews
1 / 20
10.0
ExcellentAnonymous,May 2026
SEA - KOA
Related info for your journey
Find useful and relevant information for your journey from Sioux Falls to Durham. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.
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Alternative routes for Sioux Falls to Durham
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Complete your trip
Complete your trip to Durham by adding a car rental and/or hotel reservation to your travel itinerary.
Search flights from Sioux Falls to Durham by cabin class
Find flights from Sioux Falls to Durham, based on your preferred cabin class, be it economy, premium economy, business, or first class.
Sioux Falls and Durham flights
Browse other Sioux Falls and Durham flight options. Last updated on June 19, 2026.
Other flights from Sioux Falls
Browse through other flights departing from Sioux Falls. Flights are based on user searches made on Cheapflights and were last updated on June 19, 2026.
Popular flight searches
Check out other popular destinations found by fellow travelers in 2026
Sioux Falls to Durham flights
Consider these flights traveling from Sioux Falls to Durham.
Top 3 airlines flying from Sioux Falls to Durham
Discover the top 3 airlines that operate flights from Sioux Falls to Durham. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated June 19, 2026.
| Airline | Cheapest | Average | Flexibility | On-time |
|---|---|---|---|---|
| Cheapest$258 | Average$340 | FlexibilityNo cancel fee | On-time71% | |
| Cheapest$258 | Average$358 | FlexibilityNo cancel fee | On-timeN/A | |
| Cheapest$307 | Average$473 | FlexibilityNo cancel fee | On-time69% |