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$170+ Cheap flights from Sioux Falls (FSD) to Durham, NC

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 4/29. Fares are subject to change and may not be available on all flights or dates of travel.
FSD — RDU
Mar 23 — Mar 301
Mon 3/23
Mon 3/30
1 adult, Economy
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Cheap flight deals from Sioux Falls to Durham

Cheapest flights from Sioux Falls to Durham
Explore the most affordable flight options available from Sioux Falls to Durham. Find the lowest fares from popular airlines and budget airlines, with prices last updated on February 21, 2026.

This Delta deal was found by Cheapflights users on 2/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 4/161:44 pm
FSD
-
RDU
2 stops8h 55m
Delta
Tue 4/287:01 pm
RDU
-
FSD
1 stop5h 01m
Delta
Deal found 2/18$274
This Delta deal was found by Cheapflights users on 2/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 3/274:23 pm
FSD
-
RDU
1 stop6h 36m
Delta
Tue 3/316:00 am
RDU
-
FSD
1 stop7h 53m
Delta
Deal found 2/18$304
This Delta deal was found by Cheapflights users on 2/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 9/115:15 am
FSD
-
RDU
1 stop5h 12m
Delta
Fri 9/186:40 pm
RDU
-
FSD
1 stop5h 06m
Delta
Deal found 2/20$307
This Delta deal was found by Cheapflights users on 2/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 3/204:23 pm
FSD
-
RDU
1 stop6h 36m
Delta
Fri 3/276:21 pm
RDU
-
FSD
1 stop5h 43m
Delta
Deal found 2/18$309
This United Airlines deal was found by Cheapflights users on 2/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 4/146:10 am
FSD
-
RDU
1 stop5h 00m
United Airlines
Sat 4/181:15 pm
RDU
-
FSD
1 stop5h 29m
United Airlines
Deal found 2/19$339
This Kiwi.com deal was found by Cheapflights users on 2/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 3/1711:01 am
FSD
-
RDU
1 stop9h 52m
Multiple Airlines
Thu 3/199:17 am
RDU
-
FSD
2 stops35h 42m
Multiple Airlines
Deal found 2/19$340
This Delta deal was found by Cheapflights users on 2/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 5/288:19 am
FSD
-
RDU
1 stop4h 43m
Delta
Sun 5/316:00 am
RDU
-
FSD
1 stop5h 16m
Delta
Deal found 2/20$342

Find flight deals from Sioux Falls to Durham

Keep the following information in mind while searching for Sioux Falls to Durham flight deals. Data was last updated February 21, 2026.

Most accurate provider

FlightHub
3 stars

Most trusted provider

FlightHub
3 stars

Round-trip from

$274
(Delta)

One-way from

$170
(Kiwi.com)

Popular in

January

Cheapest in

August

Average price

$323
Provider with most accurate pricing for Sioux Falls Joe Foss Field-Raleigh-Durham flight deals.
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Provider most trusted by Cheapflights users for Sioux Falls Joe Foss Field-Raleigh-Durham flights.
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From Sioux Falls Joe Foss Field to Durham
Search Deals
One-way flight from Sioux Falls Joe Foss Field to Durham
Search Deals
Highest demand for flights based on searches. 7% potential increase in price ($28 potential increase over avg. RT price).
Search Deals
Cheapest flight prices on average. 3% potential price decrease ($11 potential savings vs. average RT price).
Search Deals
Average for round-trip flights in February 2026
Search Deals

Cheapflights Fare Finder

 
Customize your flight search to find flights from Sioux Falls to Durham that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated February 21, 2026.
Use the filters below to find and compare flights from Sioux Falls to Durham that are best for you.

Fly from

Sioux Falls

Fly to

Durham

Route

Depart

Return

Price

Sioux FallsRaleigh

FSD - RDU

FSDRDU

Sioux Falls Joe Foss Field

Thu 4/16

1:44 pm-11:39 pm

2 stops8h 55m

Raleigh-Durham

Tue 4/28

7:01 pm-11:02 pm

1 stop5h 01m

$274

Sioux FallsRaleigh

FSD - RDU

FSDRDU

Sioux Falls Joe Foss Field

Fri 3/27

4:23 pm-11:59 pm

1 stop6h 36m

Raleigh-Durham

Tue 3/31

6:00 am-12:53 pm

1 stop7h 53m

$304

Sioux FallsRaleigh

FSD - RDU

FSDRDU

Sioux Falls Joe Foss Field

Fri 3/20

4:23 pm-11:59 pm

1 stop6h 36m

Raleigh-Durham

Fri 3/27

6:21 pm-11:04 pm

1 stop5h 43m

$309

Sioux FallsRaleigh

FSD - RDU

FSDRDU

Sioux Falls Joe Foss Field

Tue 4/14

6:15 am-12:10 pm

1 stop4h 55m

Raleigh-Durham

Sat 4/18

3:00 pm-9:49 pm

1 stop7h 49m

$339

Sioux FallsRaleigh

FSD - RDU

FSDRDU

Sioux Falls Joe Foss Field

Fri 3/6

7:43 am-1:42 pm

1 stop4h 59m

Raleigh-Durham

Tue 3/10

1:27 pm-5:52 pm

1 stop5h 25m

$339

Sioux FallsRaleigh

FSD - RDU

FSDRDU

Sioux Falls Joe Foss Field

Wed 4/29

4:26 pm-9:04 pm

2 stops27h 38m

$170

Sioux FallsRaleigh

FSD - RDU

FSDRDU

Sioux Falls Joe Foss Field

Fri 2/27

1:59 pm-10:03 am

2 stops19h 04m

$175

Sioux FallsRaleigh

FSD - RDU

FSDRDU

Sioux Falls Joe Foss Field

Fri 3/27

5:55 pm-12:06 am

2 stops29h 11m

$175

Sioux FallsRaleigh

FSD - RDU

FSDRDU

Sioux Falls Joe Foss Field

Wed 4/29

6:45 am-3:14 pm

1 stop7h 29m

$249

Sioux FallsRaleigh

FSD - RDU

FSDRDU

Sioux Falls Joe Foss Field

Sat 6/6

6:10 pm-5:07 pm

2 stops45h 57m

$268

Flights are sorted by cheapest round-trip flights first.

Deals found on 2/20

Showing 1-10 of 13 results
1
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Best time to book a flight from Sioux Falls to Durham

Have a flexible travel schedule? Discover the best time to fly to Durham from Sioux Falls with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Sioux Falls to Durham

What is the cheapest month to book a flight from Sioux Falls to Durham?

Currently, December is the cheapest month in which you can book a flight from Sioux Falls to Durham (average of $172). Flying from Sioux Falls to Durham in January is currently the most expensive (average of $454). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

Reviews of airlines servicing Durham

Get insights into the airlines that provide service to Durham. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Durham. Reviews last updated February 21, 2026.
See what other customers who have flown with Delta, United Airlines, and American Airlines from Sioux Falls to Durham have to say. You can also see how each airline compares in terms of entertainment options, comfort, food, crew/service, and boarding process.
Delta
7.9
Good
8,228 reviews

Comfort

7.9

Entertainment

7.8

Food

7.2

Overall

7.9

Crew

8.5

Boarding

8.1

Reviews

1 / 20
6.0
Good

Jim,Nov 2025

AVL - ATL

The exit row seats without a seat in front are great for leg room but don’t have a fold out entertainment console so you’re forced to use the screen several feet in front of you (there is, at least, a remote). Best to bring a tablet loaded with entertainment or a book.
Delta
7.9
Good
8,228 reviews
Delta
7.9
Good
8,228 reviews

Comfort

7.9

Entertainment

7.8

Food

7.2

Overall

7.9

Crew

8.5

Boarding

8.1

Reviews

1 / 20
6.0
Good

Jim,Nov 2025

AVL - ATL

The exit row seats without a seat in front are great for leg room but don’t have a fold out entertainment console so you’re forced to use the screen several feet in front of you (there is, at least, a remote). Best to bring a tablet loaded with entertainment or a book.
United Airlines
7.4
Good
9,335 reviews
Delta
7.9
Good
8,228 reviews

Comfort

7.9

Entertainment

7.8

Food

7.2

Overall

7.9

Crew

8.5

Boarding

8.1

Reviews

1 / 20
6.0
Good

Jim,Nov 2025

AVL - ATL

The exit row seats without a seat in front are great for leg room but don’t have a fold out entertainment console so you’re forced to use the screen several feet in front of you (there is, at least, a remote). Best to bring a tablet loaded with entertainment or a book.
American Airlines
7.2
Good
11,334 reviews
Delta
7.9
Good
8,228 reviews

Comfort

7.9

Entertainment

7.8

Food

7.2

Overall

7.9

Crew

8.5

Boarding

8.1

Reviews

1 / 20
6.0
Good

Jim,Nov 2025

AVL - ATL

The exit row seats without a seat in front are great for leg room but don’t have a fold out entertainment console so you’re forced to use the screen several feet in front of you (there is, at least, a remote). Best to bring a tablet loaded with entertainment or a book.

Related info for your journey

Find useful and relevant information for your journey from Sioux Falls to Durham. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • What airport do you fly from for flights from Sioux Falls to Durham?

    For a flight from Sioux Falls to Durham, you will be flying from Joe Foss Field. Sioux Falls Joe Foss Field (FSD) is just 2.6 mi from the center of the city. Joe Foss Field is the only Sioux Falls airport and it handles 0 outbound flights to Durham per day. 3 airlines have flights to Durham from Sioux Falls Joe Foss Field on a regular basis.

  • How long is the flight from Sioux Falls to Durham?

    For as low as $274, Delta can have you in Durham from Sioux Falls in 8h 55m. The distance from Sioux Falls to Durham is about 1088 mi.

  • Can I find deals for flights from Sioux Falls to Durham that include hotel bookings?

    Yes. In addition to deals on Sioux Falls to Durham flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Sioux Falls to Durham?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Sioux Falls to Durham.

  • Can I find deals for business class flights from Sioux Falls to Durham?

    Yes. Cheapflights offers flight deals from Sioux Falls to Durham by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Sioux Falls to Durham?

    Currently, December is the cheapest month in which you can book a flight from Sioux Falls to Durham (average of $172). Flying from Sioux Falls to Durham in January is currently the most expensive (average of $454). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

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Top 3 airlines flying from Sioux Falls to Durham

Discover the top 3 airlines that operate flights from Sioux Falls to Durham. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated February 21, 2026.
AirlineCheapestAverageFlexibilityOn-time
American AirlinesCheapest$198Average$308FlexibilityNo cancel feeOn-time71%
United AirlinesCheapest$236Average$473FlexibilityNo cancel feeOn-time69%
DeltaCheapest$258Average$338FlexibilityNo cancel feeOn-timeN/A

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