$121+ Cheap flights from Sioux Falls (FSD) to Durham, NC
This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 6/24. Fares are subject to change and may not be available on all flights or dates of travel.
FSD — RDU
Jun 29 — Jul 61
Round-trip
1 adult, Economy
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Find cheap flights from Sioux Falls to Durham with Cheapflights
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Best
Last-minute
One-way
Cheapest flights from Sioux Falls to DurhamExplore the most affordable flight options available from Sioux Falls to Durham. Find the lowest fares from popular airlines and budget airlines, with prices last updated on May 30, 2026.
Explore the most affordable flight options available from Sioux Falls to Durham. Find the lowest fares from popular airlines and budget airlines, with prices last updated on May 30, 2026.
This Expedia deal was found by Cheapflights users on 5/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Expedia is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 6/108:14 pm
FSD
- RDU
1 stop14h 17m
Frontier
Wed 6/1712:26 pm
RDU
- FSD
1 stop7h 53m
Frontier
Deal found 5/26![Frontier logo]()
$290
This American Airlines deal was found by Cheapflights users on 5/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 9/96:00 am
FSD
- RDU
1 stop6h 27m
American Airlines
Sat 9/126:00 am
RDU
- FSD
1 stop6h 41m
American Airlines
Deal found 5/29![American Airlines logo]()
$311
This Delta deal was found by Cheapflights users on 5/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 10/65:25 am
FSD
- RDU
1 stop7h 42m
Delta
Sat 10/106:00 am
RDU
- FSD
1 stop5h 05m
Delta
Deal found 5/27![Delta logo]()
$319
This Kiwi.com deal was found by Cheapflights users on 5/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 6/116:51 pm
FSD
- RDU
1 stop13h 28m
Multiple Airlines
Wed 6/175:30 pm
RDU
- FSD
1 stop25h 31m
Multiple Airlines
Deal found 5/26![Multiple Airlines logo]()
$324
This Booking.com deal was found by Cheapflights users on 5/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Booking.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 7/138:08 pm
FSD
- RDU
1 stop14h 23m
Frontier
Fri 7/1712:26 pm
RDU
- FSD
1 stop7h 57m
Frontier
Deal found 5/25![Frontier logo]()
$352
This Delta deal was found by Cheapflights users on 5/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 6/265:24 am
FSD
- RDU
1 stop5h 20m
Delta
Tue 6/306:00 am
RDU
- FSD
1 stop5h 16m
Delta
Deal found 5/25![Delta logo]()
$359
This United Airlines deal was found by Cheapflights users on 5/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 7/317:35 am
FSD
- RDU
1 stop5h 26m
United Airlines
Mon 8/35:12 pm
RDU
- FSD
1 stop7h 19m
United Airlines
Deal found 5/27![United Airlines logo]()
$370
Best flights from Sioux Falls to DurhamDiscover carefully curated flight deals from Sioux Falls to Durham that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated May 30, 2026.
Discover carefully curated flight deals from Sioux Falls to Durham that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated May 30, 2026.
This Delta deal was found by Cheapflights users on 5/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 9/910:58 am
FSD
- RDU
1 stop5h 54m
Delta
Sat 9/126:40 pm
RDU
- FSD
1 stop5h 06m
Delta
Deal found 5/30![Delta logo]()
$311
This Kiwi.com deal was found by Cheapflights users on 5/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 6/116:51 pm
FSD
- RDU
1 stop13h 28m
Multiple Airlines
Wed 6/175:30 pm
RDU
- FSD
1 stop25h 31m
Multiple Airlines
Deal found 5/26![Multiple Airlines logo]()
$324
This United Airlines deal was found by Cheapflights users on 5/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 7/317:35 am
FSD
- RDU
1 stop5h 26m
United Airlines
Mon 8/35:12 pm
RDU
- FSD
1 stop7h 19m
United Airlines
Deal found 5/27![United Airlines logo]()
$370
This American Airlines deal was found by Cheapflights users on 5/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 6/1312:18 pm
FSD
- RDU
1 stop6h 08m
American Airlines
Sat 6/207:03 am
RDU
- FSD
1 stop5h 36m
American Airlines
Deal found 5/29![American Airlines logo]()
$396
This Delta deal was found by Cheapflights users on 5/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 6/265:24 am
FSD
- RDU
1 stop5h 20m
Delta
Tue 6/306:00 am
RDU
- FSD
1 stop5h 16m
Delta
Deal found 5/25![Delta logo]()
$359
This United Airlines deal was found by Cheapflights users on 5/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 9/17:47 am
FSD
- RDU
1 stop5h 20m
United Airlines
Sat 9/55:09 pm
RDU
- FSD
1 stop7h 13m
United Airlines
Deal found 5/26![United Airlines logo]()
$401
This American Airlines deal was found by Cheapflights users on 5/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 6/124:40 pm
FSD
- RDU
1 stop6h 10m
American Airlines
Tue 6/163:12 pm
RDU
- FSD
2 stops10h 08m
American Airlines
Deal found 5/27![American Airlines logo]()
$419
This United Airlines deal was found by Cheapflights users on 5/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 8/287:47 am
FSD
- RDU
1 stop7h 15m
United Airlines
Mon 8/315:09 pm
RDU
- FSD
1 stop7h 13m
United Airlines
Deal found 5/29![United Airlines logo]()
$409
This American Airlines deal was found by Cheapflights users on 5/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 6/106:00 am
FSD
- RDU
2 stops8h 37m
American Airlines
Wed 6/174:28 pm
RDU
- FSD
2 stops8h 52m
American Airlines
Deal found 5/29![American Airlines logo]()
$433
This American Airlines deal was found by Cheapflights users on 5/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 6/116:00 am
FSD
- RDU
1 stop6h 28m
American Airlines
Wed 6/176:08 pm
RDU
- FSD
1 stop7h 12m
American Airlines
Deal found 5/27![American Airlines logo]()
$447
Last-minute flights from Sioux Falls to DurhamDiscover last-minute flight deals from Sioux Falls to Durham. Data last updated May 30, 2026 and is based on user searches.
Discover last-minute flight deals from Sioux Falls to Durham. Data last updated May 30, 2026 and is based on user searches.
This Expedia deal was found by Cheapflights users on 5/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Expedia is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 6/108:14 pm
FSD
- RDU
1 stop14h 17m
Frontier
Wed 6/1712:26 pm
RDU
- FSD
1 stop7h 53m
Frontier
Deal found 5/26![Frontier logo]()
$290
This American Airlines deal was found by Cheapflights users on 5/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 6/106:00 am
FSD
- RDU
1 stop6h 28m
American Airlines
Wed 6/174:28 pm
RDU
- FSD
2 stops8h 52m
American Airlines
Deal found 5/27![American Airlines logo]()
$419
This Kiwi.com deal was found by Cheapflights users on 5/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 6/116:51 pm
FSD
- RDU
1 stop13h 28m
Multiple Airlines
Wed 6/175:30 pm
RDU
- FSD
1 stop25h 31m
Multiple Airlines
Deal found 5/26![Multiple Airlines logo]()
$324
This American Airlines deal was found by Cheapflights users on 5/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 6/124:40 pm
FSD
- RDU
1 stop6h 10m
American Airlines
Tue 6/162:23 pm
RDU
- FSD
1 stop8h 54m
American Airlines
Deal found 5/27![American Airlines logo]()
$396
This American Airlines deal was found by Cheapflights users on 5/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 6/1312:18 pm
FSD
- RDU
2 stops8h 38m
American Airlines
Sat 6/207:09 pm
RDU
- FSD
1 stop6h 16m
American Airlines
Deal found 5/29![American Airlines logo]()
$401
This Delta deal was found by Cheapflights users on 5/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 6/265:24 am
FSD
- RDU
1 stop5h 20m
Delta
Tue 6/306:00 am
RDU
- FSD
1 stop5h 16m
Delta
Deal found 5/25![Delta logo]()
$359
One-way flights from Sioux Falls to DurhamSearch for one-way flight options from Sioux Falls to Durham. Find affordable one-way fares based on user searches. Data last updated May 30, 2026.
Search for one-way flight options from Sioux Falls to Durham. Find affordable one-way fares based on user searches. Data last updated May 30, 2026.
This Expedia deal was found by Cheapflights users on 5/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Expedia is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 6/248:14 pm
FSD
- RDU
1 stop14h 17m
Frontier
Deal found 5/28![Frontier logo]()
$121
This Expedia deal was found by Cheapflights users on 5/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Expedia is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 6/298:14 pm
FSD
- RDU
1 stop14h 17m
Frontier
Deal found 5/30![Frontier logo]()
$164
This Kiwi.com deal was found by Cheapflights users on 5/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 6/186:51 pm
FSD
- RDU
1 stop13h 09m
Multiple Airlines
Deal found 5/28![Multiple Airlines logo]()
$192
This Kiwi.com deal was found by Cheapflights users on 5/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 6/256:51 pm
FSD
- RDU
1 stop13h 09m
Multiple Airlines
Deal found 5/28![Multiple Airlines logo]()
$226
This Kiwi.com deal was found by Cheapflights users on 5/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 8/1510:33 am
FSD
- RDU
2 stops43h 49m
Multiple Airlines
Deal found 5/26![Multiple Airlines logo]()
$243
This Kiwi.com deal was found by Cheapflights users on 5/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 6/299:57 am
FSD
- RDU
2 stops30h 53m
Multiple Airlines
Deal found 5/30![Multiple Airlines logo]()
$250
This Kiwi.com deal was found by Cheapflights users on 5/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 6/229:07 pm
FSD
- RDU
3 stops59h 12m
Multiple Airlines
Deal found 5/30![Multiple Airlines logo]()
$283
This Orbitz deal was found by Cheapflights users on 5/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Orbitz is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 6/228:14 pm
FSD
- RDU
1 stop14h 17m
Frontier
Deal found 5/30![Frontier logo]()
$294
Find flight deals from Sioux Falls to Durham
Keep the following information in mind while searching for Sioux Falls to Durham flight deals. Data was last updated May 30, 2026.
Most accurate provider | FlightHub 3 stars |
|---|---|
Most trusted provider | FlightHub 3 stars |
Round-trip from | $290 (Expedia) |
One-way from | $121 (Expedia) |
Popular in | March |
Cheapest in | August |
Average price | $365 |
Cheapflights Fare Finder
Customize your flight search to find flights from Sioux Falls to Durham that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated May 30, 2026.
Use the filters below to find and compare flights from Sioux Falls to Durham that are best for you.
Fly from
Fly to
Route
Depart
Return
Cheapest round-trip
Sioux FallsRaleigh
FSD - RDU
FSDRDU
Sioux Falls Joe Foss Field
Wed 9/9
10:58 am-5:52 pm
1 stop5h 54m
Raleigh-Durham
Sat 9/12
6:40 pm-10:46 pm
1 stop5h 06m
$311
Sioux FallsRaleigh
FSD - RDU
FSDRDU
Sioux Falls Joe Foss Field
Thu 6/11
6:51 pm-9:19 am
1 stop13h 28m
Raleigh-Durham
Wed 6/17
5:30 pm-6:01 pm
1 stop25h 31m
$324
Quickest round-trip
Sioux FallsRaleigh
FSD - RDU
FSDRDU
Sioux Falls Joe Foss Field
Fri 6/26
5:24 am-11:44 am
1 stop5h 20m
Raleigh-Durham
Tue 6/30
6:00 am-10:16 am
1 stop5h 16m
$359
Sioux FallsRaleigh
FSD - RDU
FSDRDU
Sioux Falls Joe Foss Field
Fri 7/31
7:35 am-2:01 pm
1 stop5h 26m
Raleigh-Durham
Mon 8/3
5:12 pm-11:31 pm
1 stop7h 19m
$370
Sioux FallsRaleigh
FSD - RDU
FSDRDU
Sioux Falls Joe Foss Field
Sat 6/13
12:18 pm-7:26 pm
1 stop6h 08m
Raleigh-Durham
Sat 6/20
7:03 am-11:39 am
1 stop5h 36m
$396
Sioux FallsRaleigh
FSD - RDU
FSDRDU
Sioux Falls Joe Foss Field
Tue 9/1
7:47 am-2:07 pm
1 stop5h 20m
Raleigh-Durham
Sat 9/5
5:09 pm-11:22 pm
1 stop7h 13m
$401
Sioux FallsRaleigh
FSD - RDU
FSDRDU
Sioux Falls Joe Foss Field
Fri 8/28
7:47 am-4:02 pm
1 stop7h 15m
Raleigh-Durham
Mon 8/31
5:09 pm-11:22 pm
1 stop7h 13m
$409
Sioux FallsRaleigh
FSD - RDU
FSDRDU
Sioux Falls Joe Foss Field
Fri 6/12
4:40 pm-11:50 pm
1 stop6h 10m
Raleigh-Durham
Tue 6/16
3:12 pm-12:20 am
2 stops10h 08m
$419
Sioux FallsRaleigh
FSD - RDU
FSDRDU
Sioux Falls Joe Foss Field
Wed 6/10
6:00 am-3:37 pm
2 stops8h 37m
Raleigh-Durham
Wed 6/17
4:28 pm-12:20 am
2 stops8h 52m
$433
Sioux FallsRaleigh
FSD - RDU
FSDRDU
Sioux Falls Joe Foss Field
Thu 6/11
6:00 am-1:28 pm
1 stop6h 28m
Raleigh-Durham
Wed 6/17
6:08 pm-12:20 am
1 stop7h 12m
$447
Showing 1-10 of 21 resultsSorted by cheapest first
Best time to book a flight from Sioux Falls to Durham
Have a flexible travel schedule? Discover the best time to fly to Durham from Sioux Falls with our price prediction graph.
FSD-RDU
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.
Cheapflights Insights
Everything you need to know about your flight from Sioux Falls to Durham
FSD-DU8
FSD-RDU
How much does it cost to fly round-trip from Sioux Falls to Durham?
Reviews of airlines servicing Durham
Get insights into the airlines that provide service to Durham. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Durham. Reviews last updated May 30, 2026.
See what other customers who have flown with Delta,United Airlines, andAmerican Airlines from Sioux Falls to Durham have to say. You can also see how each airline compares in terms of entertainment options, comfort, food, crew/service, and boarding process.
Boarding
8.1
Entertainment
7.8
Crew
8.5
Comfort
7.8
Food
7.2
Overall
7.9
Reviews
1 / 20
10.0
ExcellentAnonymous,May 2026
SEA - KOA
Boarding
8.1
Entertainment
7.8
Crew
8.5
Comfort
7.8
Food
7.2
Overall
7.9
Reviews
1 / 20
10.0
ExcellentAnonymous,May 2026
SEA - KOA
Boarding
8.1
Entertainment
7.8
Crew
8.5
Comfort
7.8
Food
7.2
Overall
7.9
Reviews
1 / 20
10.0
ExcellentAnonymous,May 2026
SEA - KOA
Boarding
8.1
Entertainment
7.8
Crew
8.5
Comfort
7.8
Food
7.2
Overall
7.9
Reviews
1 / 20
10.0
ExcellentAnonymous,May 2026
SEA - KOA
Related info for your journey
Find useful and relevant information for your journey from Sioux Falls to Durham. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.
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Find flights from Sioux Falls to Durham, based on your preferred cabin class, be it economy, premium economy, business, or first class.
Sioux Falls and Durham flights
Browse other Sioux Falls and Durham flight options. Last updated on May 30, 2026.
Other flights from Sioux Falls
Browse through other flights departing from Sioux Falls. Flights are based on user searches made on Cheapflights and were last updated on May 30, 2026.
Popular flight searches
Check out other popular destinations found by fellow travelers in 2026
Sioux Falls to Durham flights
Consider these flights traveling from Sioux Falls to Durham.
Top 3 airlines flying from Sioux Falls to Durham
Discover the top 3 airlines that operate flights from Sioux Falls to Durham. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated May 30, 2026.
| Airline | Cheapest | Average | Flexibility | On-time |
|---|---|---|---|---|
| Cheapest$258 | Average$366 | FlexibilityNo cancel fee | On-time71% | |
| Cheapest$258 | Average$355 | FlexibilityNo cancel fee | On-timeN/A | |
| Cheapest$307 | Average$498 | FlexibilityNo cancel fee | On-time69% |