HomeSearch by dateVacation packagesHotelsFlight dealsCar rentalTravel tips & news
Durham

$180+ Cheap flights from Sioux Falls (FSD) to Durham, NC

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 2/24. Fares are subject to change and may not be available on all flights or dates of travel.
FSD — RDU
Mar 14 — Mar 211
Sat 3/14
Sat 3/21
1 adult, Economy
We work with more than 300 partners to bring you better travel deals

Find cheap flights from Sioux Falls to Durham with Cheapflights

1. Tell us where you want to go

Enter your travel information like dates, passengers, trip type (one-way or round trip), and preferred cabin class then click “Find deals”

2. Select your favorite providers

We find the providers serving your travel needs. Choose up to four travel providers to compare side-by-side for flights, hotels, or car rentals.

3. Compare prices and book

Review each provider’s pricing and select the best option for you! Book through your favorite provider’s website for a seamless experience.

Cheap flight deals from Sioux Falls to Durham

Cheapest flights from Sioux Falls to Durham
Explore the most affordable flight options available from Sioux Falls to Durham. Find the lowest fares from popular airlines and budget airlines, with prices last updated on February 12, 2026.

This United Airlines deal was found by Cheapflights users on 2/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 4/811:20 am
FSD
-
RDU
1 stop4h 58m
United Airlines
Mon 4/135:20 pm
RDU
-
FSD
1 stop5h 29m
United Airlines
Deal found 2/11$295
This Delta deal was found by Cheapflights users on 2/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 4/305:05 am
FSD
-
RDU
1 stop4h 34m
Delta
Tue 5/57:01 pm
RDU
-
FSD
1 stop5h 01m
Delta
Deal found 2/9$304
This Delta deal was found by Cheapflights users on 2/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 5/288:19 am
FSD
-
RDU
1 stop4h 43m
Delta
Sun 5/316:00 am
RDU
-
FSD
1 stop5h 16m
Delta
Deal found 2/9$307
This United Airlines deal was found by Cheapflights users on 2/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 2/257:40 am
FSD
-
RDU
2 stops10h 11m
United Airlines
Sun 3/16:29 am
RDU
-
FSD
1 stop5h 17m
United Airlines
Deal found 2/10$346
This Delta deal was found by Cheapflights users on 2/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 2/244:19 pm
FSD
-
RDU
1 stop6h 30m
Delta
Sun 3/16:00 am
RDU
-
FSD
1 stop5h 08m
Delta
Deal found 2/9$347
This Delta deal was found by Cheapflights users on 2/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 4/168:05 am
FSD
-
RDU
1 stop4h 56m
Delta
Tue 4/2811:34 am
RDU
-
FSD
1 stop5h 03m
Delta
Deal found 2/9$350
This Delta deal was found by Cheapflights users on 2/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 4/105:20 am
FSD
-
RDU
1 stop7h 13m
Delta
Sun 4/126:00 am
RDU
-
FSD
1 stop5h 21m
Delta
Deal found 2/9$353
This American Airlines deal was found by Cheapflights users on 2/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 3/312:14 pm
FSD
-
RDU
1 stop4h 26m
American Airlines
Sat 3/75:00 am
RDU
-
FSD
1 stop7h 42m
American Airlines
Deal found 2/10$357

Find flight deals from Sioux Falls to Durham

Keep the following information in mind while searching for Sioux Falls to Durham flight deals. Data was last updated February 12, 2026.

Most accurate provider

FlightHub
3 stars

Most trusted provider

FlightHub
3 stars

Round-trip from

$295
(United Airlines)

One-way from

$180
(Kiwi.com)

Popular in

January

Cheapest in

August

Average price

$323
Provider with most accurate pricing for Sioux Falls Joe Foss Field-Raleigh-Durham flight deals.
Search Deals
Provider most trusted by Cheapflights users for Sioux Falls Joe Foss Field-Raleigh-Durham flights.
Search Deals
From Sioux Falls Joe Foss Field to Durham
Search Deals
One-way flight from Sioux Falls Joe Foss Field to Durham
Search Deals
Highest demand for flights based on searches. 5% potential increase in price ($21 potential increase over avg. RT price).
Search Deals
Cheapest flight prices on average. 2% potential price decrease ($10 potential savings vs. average RT price).
Search Deals
Average for round-trip flights in February 2026
Search Deals

Cheapflights Fare Finder

 
Customize your flight search to find flights from Sioux Falls to Durham that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated February 12, 2026.
Use the filters below to find and compare flights from Sioux Falls to Durham that are best for you.

Fly from

Sioux Falls

Fly to

Durham

Route

Depart

Return

Price

Sioux FallsRaleigh

FSD - RDU

FSDRDU

Sioux Falls Joe Foss Field

Wed 4/8

11:20 am-5:18 pm

1 stop4h 58m

Raleigh-Durham

Mon 4/13

5:20 pm-9:49 pm

1 stop5h 29m

$295

Sioux FallsRaleigh

FSD - RDU

FSDRDU

Sioux Falls Joe Foss Field

Thu 4/30

5:05 am-10:39 am

1 stop4h 34m

Raleigh-Durham

Tue 5/5

7:01 pm-11:02 pm

1 stop5h 01m

$304

Sioux FallsRaleigh

FSD - RDU

FSDRDU

Sioux Falls Joe Foss Field

Thu 5/28

8:19 am-2:02 pm

1 stop4h 43m

Raleigh-Durham

Sun 5/31

6:00 am-10:16 am

1 stop5h 16m

$307

Sioux FallsRaleigh

FSD - RDU

FSDRDU

Sioux Falls Joe Foss Field

Wed 2/25

7:40 am-6:51 pm

2 stops10h 11m

Raleigh-Durham

Sun 3/1

6:29 am-10:46 am

1 stop5h 17m

$346

Sioux FallsRaleigh

FSD - RDU

FSDRDU

Sioux Falls Joe Foss Field

Thu 4/16

8:05 am-2:01 pm

1 stop4h 56m

Raleigh-Durham

Tue 4/28

11:34 am-3:37 pm

1 stop5h 03m

$350

Sioux FallsRaleigh

FSD - RDU

FSDRDU

Sioux Falls Joe Foss Field

Tue 2/24

4:19 pm-12:09 am

2 stops6h 50m

Raleigh-Durham

Sun 3/1

6:00 am-10:08 am

1 stop5h 08m

$352

Sioux FallsRaleigh

FSD - RDU

FSDRDU

Sioux Falls Joe Foss Field

Fri 4/10

5:20 am-1:33 pm

1 stop7h 13m

Raleigh-Durham

Sun 4/12

6:00 am-10:21 am

1 stop5h 21m

$353

Sioux FallsRaleigh

FSD - RDU

FSDRDU

Sioux Falls Joe Foss Field

Tue 2/24

12:03 pm-1:58 pm

1 stop24h 55m

$180

Sioux FallsRaleigh

FSD - RDU

FSDRDU

Sioux Falls Joe Foss Field

Fri 3/20

5:55 pm-8:27 am

2 stops37h 32m

$200

Sioux FallsRaleigh

FSD - RDU

FSDRDU

Sioux Falls Joe Foss Field

Sat 3/21

7:43 am-1:42 pm

1 stop4h 59m

$281

Flights are sorted by cheapest round-trip flights first.

Deals found on 2/11

Showing 1-10 of 13 results
1
2

Best time to book a flight from Sioux Falls to Durham

Have a flexible travel schedule? Discover the best time to fly to Durham from Sioux Falls with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Sioux Falls to Durham

What is the cheapest month to book a flight from Sioux Falls to Durham?

Currently, December is the cheapest month in which you can book a flight from Sioux Falls to Durham (average of $172). Flying from Sioux Falls to Durham in January is currently the most expensive (average of $454). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

Reviews of airlines servicing Durham

Get insights into the airlines that provide service to Durham. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Durham. Reviews last updated February 12, 2026.
See what other customers who have flown with Delta, United Airlines, and American Airlines from Sioux Falls to Durham have to say. You can also see how each airline compares in terms of entertainment options, comfort, food, crew/service, and boarding process.
Delta
7.9
Good
8,179 reviews

Boarding

8.1

Comfort

7.9

Food

7.2

Entertainment

7.8

Crew

8.5

Overall

7.9

Reviews

1 / 20
6.0
Good

Jim,Nov 2025

AVL - ATL

The exit row seats without a seat in front are great for leg room but don’t have a fold out entertainment console so you’re forced to use the screen several feet in front of you (there is, at least, a remote). Best to bring a tablet loaded with entertainment or a book.
Delta
7.9
Good
8,179 reviews
Delta
7.9
Good
8,179 reviews

Boarding

8.1

Comfort

7.9

Food

7.2

Entertainment

7.8

Crew

8.5

Overall

7.9

Reviews

1 / 20
6.0
Good

Jim,Nov 2025

AVL - ATL

The exit row seats without a seat in front are great for leg room but don’t have a fold out entertainment console so you’re forced to use the screen several feet in front of you (there is, at least, a remote). Best to bring a tablet loaded with entertainment or a book.
United Airlines
7.4
Good
9,276 reviews
Delta
7.9
Good
8,179 reviews

Boarding

8.1

Comfort

7.9

Food

7.2

Entertainment

7.8

Crew

8.5

Overall

7.9

Reviews

1 / 20
6.0
Good

Jim,Nov 2025

AVL - ATL

The exit row seats without a seat in front are great for leg room but don’t have a fold out entertainment console so you’re forced to use the screen several feet in front of you (there is, at least, a remote). Best to bring a tablet loaded with entertainment or a book.
American Airlines
7.2
Good
11,267 reviews
Delta
7.9
Good
8,179 reviews

Boarding

8.1

Comfort

7.9

Food

7.2

Entertainment

7.8

Crew

8.5

Overall

7.9

Reviews

1 / 20
6.0
Good

Jim,Nov 2025

AVL - ATL

The exit row seats without a seat in front are great for leg room but don’t have a fold out entertainment console so you’re forced to use the screen several feet in front of you (there is, at least, a remote). Best to bring a tablet loaded with entertainment or a book.

Related info for your journey

Find useful and relevant information for your journey from Sioux Falls to Durham. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • What airport do you fly from for flights from Sioux Falls to Durham?

    For a flight from Sioux Falls to Durham, you will be flying from Joe Foss Field. Sioux Falls Joe Foss Field (FSD) is just 2.6 mi from the center of the city. Joe Foss Field is the only Sioux Falls airport and it handles 0 outbound flights to Durham per day. 3 airlines have flights to Durham from Sioux Falls Joe Foss Field on a regular basis.

  • How long is the flight from Sioux Falls to Durham?

    For as low as $304, United Airlines can have you in Durham from Sioux Falls in 4h 34m. The distance from Sioux Falls to Durham is about 1088 mi. When browsing for deals, the options you’ll see will be for both nonstop flights and flights with stops.

  • Can I find deals for flights from Sioux Falls to Durham that include hotel bookings?

    Yes. In addition to deals on Sioux Falls to Durham flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Sioux Falls to Durham?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Sioux Falls to Durham.

  • Can I find deals for business class flights from Sioux Falls to Durham?

    Yes. Cheapflights offers flight deals from Sioux Falls to Durham by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Sioux Falls to Durham?

    Currently, December is the cheapest month in which you can book a flight from Sioux Falls to Durham (average of $172). Flying from Sioux Falls to Durham in January is currently the most expensive (average of $454). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

Browse thousands of different options on Cheapflights for your next trip

Toggle through the tabs below to find thousands of options on Cheapflights for your next trip.

Top 3 airlines flying from Sioux Falls to Durham

Discover the top 3 airlines that operate flights from Sioux Falls to Durham. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated February 12, 2026.
AirlineCheapestAverageFlexibilityOn-time
American AirlinesCheapest$198Average$318FlexibilityNo cancel feeOn-time71%
United AirlinesCheapest$236Average$473FlexibilityNo cancel feeOn-time69%
DeltaCheapest$258Average$328FlexibilityNo cancel feeOn-timeN/A

100% Free

Cheapflights is completely free to use, so you can start saving the moment you arrive.

Book with Flexibility

Our users can plan ahead with confidence and find flights with no change fees

Travel Smart

Millions of people come to us for their flight needs every year. We help make travel planning easy by providing useful insights and data-driven graphs that can inform your decisions.