$132+ Cheap flights from Sioux Falls (FSD) to Durham, NC
This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 5/4. Fares are subject to change and may not be available on all flights or dates of travel.
FSD — RDU
May 18 — May 251
Round-trip
1 adult, Economy
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Find cheap flights from Sioux Falls to Durham with Cheapflights
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Enter your travel information like dates, passengers, trip type (one-way or round trip), and preferred cabin class then click “Find deals”2. Select your favorite providers
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Cheapest flights from Sioux Falls to DurhamExplore the most affordable flight options available from Sioux Falls to Durham. Find the lowest fares from popular airlines and budget airlines, with prices last updated on April 18, 2026.
Explore the most affordable flight options available from Sioux Falls to Durham. Find the lowest fares from popular airlines and budget airlines, with prices last updated on April 18, 2026.
This Kiwi.com deal was found by Cheapflights users on 4/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 5/186:11 pm
FSD
- RDU
2 stops16h 53m
Multiple Airlines
Mon 6/17:53 pm
RDU
- FSD
1 stop17h 38m
Multiple Airlines
Deal found 4/14![Multiple Airlines logo]()
$265
This Kiwi.com deal was found by Cheapflights users on 4/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 5/165:26 pm
FSD
- RDU
2 stops41h 05m
Multiple Airlines
Sat 5/237:52 pm
RDU
- FSD
1 stop23h 20m
Multiple Airlines
Deal found 4/17![Multiple Airlines logo]()
$294
This United Airlines deal was found by Cheapflights users on 4/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 5/236:37 pm
FSD
- RDU
1 stop5h 13m
United Airlines
Sat 5/305:07 pm
RDU
- FSD
1 stop6h 00m
United Airlines
Deal found 4/14![United Airlines logo]()
$311
This Delta deal was found by Cheapflights users on 4/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 10/65:15 am
FSD
- RDU
1 stop5h 17m
Delta
Sat 10/101:50 pm
RDU
- FSD
2 stops10h 01m
Delta
Deal found 4/16![Delta logo]()
$316
This Kiwi.com deal was found by Cheapflights users on 4/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 5/186:11 pm
FSD
- RDU
2 stops16h 53m
Multiple Airlines
Wed 6/37:52 pm
RDU
- FSD
1 stop23h 09m
Multiple Airlines
Deal found 4/14![Multiple Airlines logo]()
$319
This Travelocity deal was found by Cheapflights users on 4/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Travelocity is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 7/38:14 pm
FSD
- RDU
1 stop14h 17m
Frontier
Fri 7/1012:26 pm
RDU
- FSD
1 stop7h 53m
Frontier
Deal found 4/16![Frontier logo]()
$324
This American Airlines deal was found by Cheapflights users on 4/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 5/81:41 pm
FSD
- RDU
1 stop6h 29m
American Airlines
Sat 5/163:54 pm
RDU
- FSD
1 stop8h 12m
American Airlines
Deal found 4/14![American Airlines logo]()
$325
This Kiwi.com deal was found by Cheapflights users on 4/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 5/203:39 pm
FSD
- RDU
2 stops18h 52m
Multiple Airlines
Mon 6/17:53 pm
RDU
- FSD
1 stop17h 38m
Multiple Airlines
Deal found 4/14![Multiple Airlines logo]()
$326
This Kiwi.com deal was found by Cheapflights users on 4/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 5/39:10 pm
FSD
- RDU
2 stops22h 27m
Multiple Airlines
Wed 5/67:49 pm
RDU
- FSD
1 stop15h 56m
Multiple Airlines
Deal found 4/13![Multiple Airlines logo]()
$328
Best flights from Sioux Falls to DurhamDiscover carefully curated flight deals from Sioux Falls to Durham that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated April 18, 2026.
Discover carefully curated flight deals from Sioux Falls to Durham that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated April 18, 2026.
This United Airlines deal was found by Cheapflights users on 4/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 5/166:52 pm
FSD
- RDU
1 stop4h 58m
United Airlines
Sat 5/235:07 pm
RDU
- FSD
1 stop6h 00m
United Airlines
Deal found 4/15![United Airlines logo]()
$311
This Delta deal was found by Cheapflights users on 4/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 7/11:53 pm
FSD
- RDU
2 stops8h 35m
Delta
Wed 7/86:00 am
RDU
- FSD
1 stop7h 49m
Delta
Deal found 4/16![Delta logo]()
$316
This Delta deal was found by Cheapflights users on 4/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 6/175:20 am
FSD
- RDU
1 stop6h 24m
Delta
Sun 6/211:49 pm
RDU
- FSD
1 stop7h 10m
Delta
Deal found 4/16![Delta logo]()
$325
This United Airlines deal was found by Cheapflights users on 4/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 5/67:30 am
FSD
- RDU
1 stop5h 39m
United Airlines
Sun 5/106:20 am
RDU
- FSD
1 stop5h 25m
United Airlines
Deal found 4/13![United Airlines logo]()
$339
This Delta deal was found by Cheapflights users on 4/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 5/165:20 am
FSD
- RDU
1 stop5h 32m
Delta
Sat 5/237:05 pm
RDU
- FSD
1 stop5h 06m
Delta
Deal found 4/17![Delta logo]()
$325
This United Airlines deal was found by Cheapflights users on 4/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 5/26:00 am
FSD
- RDU
1 stop8h 12m
United Airlines
Wed 5/65:26 pm
RDU
- FSD
1 stop5h 26m
United Airlines
Deal found 4/13![United Airlines logo]()
$354
This Delta deal was found by Cheapflights users on 4/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 7/31:53 pm
FSD
- RDU
2 stops9h 49m
Delta
Fri 7/102:49 pm
RDU
- FSD
1 stop5h 47m
Delta
Deal found 4/16![Delta logo]()
$330
This Delta deal was found by Cheapflights users on 4/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 5/165:20 am
FSD
- RDU
1 stop5h 32m
Delta
Sun 5/245:20 am
RDU
- FSD
2 stops8h 29m
Delta
Deal found 4/17![Delta logo]()
$344
This Delta deal was found by Cheapflights users on 4/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 5/65:25 am
FSD
- RDU
2 stops9h 41m
Delta
Sun 5/105:20 am
RDU
- FSD
2 stops8h 29m
Delta
Deal found 4/14![Delta logo]()
$349
This Delta deal was found by Cheapflights users on 4/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 6/305:20 am
FSD
- RDU
1 stop6h 17m
Delta
Wed 7/85:20 am
RDU
- FSD
2 stops8h 29m
Delta
Deal found 4/16![Delta logo]()
$350
This Delta deal was found by Cheapflights users on 4/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 7/221:30 pm
FSD
- RDU
2 stops8h 55m
Delta
Sat 7/257:07 pm
RDU
- FSD
1 stop4h 59m
Delta
Deal found 4/16![Delta logo]()
$350
Last-minute flights from Sioux Falls to DurhamDiscover last-minute flight deals from Sioux Falls to Durham. Data last updated April 18, 2026 and is based on user searches.
Discover last-minute flight deals from Sioux Falls to Durham. Data last updated April 18, 2026 and is based on user searches.
This Kiwi.com deal was found by Cheapflights users on 4/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 5/39:10 pm
FSD
- RDU
2 stops22h 27m
Multiple Airlines
Wed 5/67:49 pm
RDU
- FSD
1 stop15h 56m
Multiple Airlines
Deal found 4/13![Multiple Airlines logo]()
$328
This American Airlines deal was found by Cheapflights users on 4/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 5/81:41 pm
FSD
- RDU
1 stop6h 29m
American Airlines
Sat 5/163:54 pm
RDU
- FSD
1 stop8h 12m
American Airlines
Deal found 4/14![American Airlines logo]()
$325
This Delta deal was found by Cheapflights users on 4/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 5/125:00 am
FSD
- RDU
1 stop4h 36m
Delta
Fri 5/227:06 pm
RDU
- FSD
1 stop5h 05m
Delta
Deal found 4/15![Delta logo]()
$339
This Kiwi.com deal was found by Cheapflights users on 4/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 5/165:26 pm
FSD
- RDU
2 stops41h 05m
Multiple Airlines
Sat 5/237:52 pm
RDU
- FSD
1 stop23h 20m
Multiple Airlines
Deal found 4/17![Multiple Airlines logo]()
$294
This American Airlines deal was found by Cheapflights users on 4/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 5/166:52 am
FSD
- RDU
1 stop5h 15m
American Airlines
Sat 5/233:12 pm
RDU
- FSD
2 stops8h 45m
American Airlines
Deal found 4/15![American Airlines logo]()
$316
This Kiwi.com deal was found by Cheapflights users on 4/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 5/186:11 pm
FSD
- RDU
2 stops16h 53m
Multiple Airlines
Mon 6/17:53 pm
RDU
- FSD
1 stop17h 38m
Multiple Airlines
Deal found 4/14![Multiple Airlines logo]()
$265
This Kiwi.com deal was found by Cheapflights users on 4/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 5/186:11 pm
FSD
- RDU
2 stops16h 53m
Multiple Airlines
Wed 6/37:52 pm
RDU
- FSD
1 stop23h 09m
Multiple Airlines
Deal found 4/14![Multiple Airlines logo]()
$319
This Kiwi.com deal was found by Cheapflights users on 4/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 5/203:39 pm
FSD
- RDU
2 stops18h 52m
Multiple Airlines
Mon 6/17:53 pm
RDU
- FSD
1 stop17h 38m
Multiple Airlines
Deal found 4/14![Multiple Airlines logo]()
$326
This United Airlines deal was found by Cheapflights users on 4/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 5/236:37 pm
FSD
- RDU
1 stop5h 13m
United Airlines
Sat 5/305:07 pm
RDU
- FSD
1 stop6h 00m
United Airlines
Deal found 4/14![United Airlines logo]()
$311
One-way flights from Sioux Falls to DurhamSearch for one-way flight options from Sioux Falls to Durham. Find affordable one-way fares based on user searches. Data last updated April 18, 2026.
Search for one-way flight options from Sioux Falls to Durham. Find affordable one-way fares based on user searches. Data last updated April 18, 2026.
This Kiwi.com deal was found by Cheapflights users on 4/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 5/46:11 pm
FSD
- RDU
2 stops16h 53m
Multiple Airlines
Deal found 4/14![Multiple Airlines logo]()
$132
This Expedia deal was found by Cheapflights users on 4/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Expedia is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 7/158:14 pm
FSD
- RDU
1 stop14h 17m
Frontier
Deal found 4/17![Frontier logo]()
$151
This Kiwi.com deal was found by Cheapflights users on 4/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 4/276:11 pm
FSD
- RDU
2 stops21h 45m
Multiple Airlines
Deal found 4/14![Multiple Airlines logo]()
$153
This Kiwi.com deal was found by Cheapflights users on 4/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 5/48:06 pm
FSD
- RDU
1 stop15h 22m
Frontier
Deal found 4/14![Frontier logo]()
$163
This Kiwi.com deal was found by Cheapflights users on 4/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 5/88:53 pm
FSD
- RDU
2 stops14h 35m
Multiple Airlines
Deal found 4/14![Multiple Airlines logo]()
$177
This Kiwi.com deal was found by Cheapflights users on 4/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 5/67:18 pm
FSD
- RDU
2 stops15h 44m
Frontier
Deal found 4/14![Frontier logo]()
$188
This Kiwi.com deal was found by Cheapflights users on 4/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 5/299:26 am
FSD
- RDU
2 stops22h 55m
Multiple Airlines
Deal found 4/14![Multiple Airlines logo]()
$210
This Delta deal was found by Cheapflights users on 4/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 5/55:00 am
FSD
- RDU
2 stops10h 16m
Delta
Deal found 4/14![Delta logo]()
$234
Find flight deals from Sioux Falls to Durham
Keep the following information in mind while searching for Sioux Falls to Durham flight deals. Data was last updated April 18, 2026.
Most accurate provider | FlightHub 3 stars |
|---|---|
Most trusted provider | FlightHub 3 stars |
Round-trip from | $265 (Kiwi.com) |
One-way from | $132 (Kiwi.com) |
Popular in | April |
Cheapest in | August |
Average price | $523 |
Cheapflights Fare Finder
Customize your flight search to find flights from Sioux Falls to Durham that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated April 18, 2026.
Use the filters below to find and compare flights from Sioux Falls to Durham that are best for you.
Fly from
Fly to
Route
Depart
Return
Cheapest round-trip
Sioux FallsRaleigh
FSD - RDU
FSDRDU
Sioux Falls Joe Foss Field
Sat 5/16
6:52 pm-12:50 am
1 stop4h 58m
Raleigh-Durham
Sat 5/23
5:07 pm-10:07 pm
1 stop6h 00m
$311
Sioux FallsRaleigh
FSD - RDU
FSDRDU
Sioux Falls Joe Foss Field
Wed 7/1
1:53 pm-11:28 pm
2 stops8h 35m
Raleigh-Durham
Wed 7/8
6:00 am-12:49 pm
1 stop7h 49m
$316
Sioux FallsRaleigh
FSD - RDU
FSDRDU
Sioux Falls Joe Foss Field
Wed 6/17
5:20 am-12:44 pm
1 stop6h 24m
Raleigh-Durham
Sun 6/21
1:49 pm-7:59 pm
1 stop7h 10m
$325
Quickest round-trip
Sioux FallsRaleigh
FSD - RDU
FSDRDU
Sioux Falls Joe Foss Field
Sat 5/16
5:20 am-11:52 am
1 stop5h 32m
Raleigh-Durham
Sat 5/23
7:05 pm-11:11 pm
1 stop5h 06m
$325
Sioux FallsRaleigh
FSD - RDU
FSDRDU
Sioux Falls Joe Foss Field
Fri 7/3
1:53 pm-12:42 am
2 stops9h 49m
Raleigh-Durham
Fri 7/10
2:49 pm-7:36 pm
1 stop5h 47m
$330
Sioux FallsRaleigh
FSD - RDU
FSDRDU
Sioux Falls Joe Foss Field
Wed 5/6
7:30 am-2:09 pm
1 stop5h 39m
Raleigh-Durham
Sun 5/10
6:20 am-10:45 am
1 stop5h 25m
$339
Sioux FallsRaleigh
FSD - RDU
FSDRDU
Sioux Falls Joe Foss Field
Sat 5/16
5:20 am-11:52 am
1 stop5h 32m
Raleigh-Durham
Sun 5/24
5:20 am-12:49 pm
2 stops8h 29m
$344
Sioux FallsRaleigh
FSD - RDU
FSDRDU
Sioux Falls Joe Foss Field
Wed 5/6
5:25 am-4:06 pm
2 stops9h 41m
Raleigh-Durham
Sun 5/10
5:20 am-12:49 pm
2 stops8h 29m
$349
Sioux FallsRaleigh
FSD - RDU
FSDRDU
Sioux Falls Joe Foss Field
Tue 6/30
5:20 am-12:37 pm
1 stop6h 17m
Raleigh-Durham
Wed 7/8
5:20 am-12:49 pm
2 stops8h 29m
$350
Sioux FallsRaleigh
FSD - RDU
FSDRDU
Sioux Falls Joe Foss Field
Wed 7/22
1:30 pm-11:25 pm
2 stops8h 55m
Raleigh-Durham
Sat 7/25
7:07 pm-11:06 pm
1 stop4h 59m
$350
Showing 1-10 of 19 resultsSorted by cheapest first
Best time to book a flight from Sioux Falls to Durham
Have a flexible travel schedule? Discover the best time to fly to Durham from Sioux Falls with our price prediction graph.
FSD-RDU
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.
Cheapflights Insights
Everything you need to know about your flight from Sioux Falls to Durham
FSD-DU8
FSD-RDU
How much does it cost to fly round-trip from Sioux Falls to Durham?
Reviews of airlines servicing Durham
Get insights into the airlines that provide service to Durham. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Durham. Reviews last updated April 18, 2026.
See what other customers who have flown with Delta,United Airlines, andAmerican Airlines from Sioux Falls to Durham have to say. You can also see how each airline compares in terms of entertainment options, comfort, food, crew/service, and boarding process.
Comfort
7.9
Boarding
8.1
Food
7.2
Crew
8.5
Entertainment
7.8
Overall
7.9
Reviews
1 / 20
6.0
GoodJim,Nov 2025
AVL - ATL
Comfort
7.9
Boarding
8.1
Food
7.2
Crew
8.5
Entertainment
7.8
Overall
7.9
Reviews
1 / 20
6.0
GoodJim,Nov 2025
AVL - ATL
Comfort
7.9
Boarding
8.1
Food
7.2
Crew
8.5
Entertainment
7.8
Overall
7.9
Reviews
1 / 20
6.0
GoodJim,Nov 2025
AVL - ATL
Comfort
7.9
Boarding
8.1
Food
7.2
Crew
8.5
Entertainment
7.8
Overall
7.9
Reviews
1 / 20
6.0
GoodJim,Nov 2025
AVL - ATL
Related info for your journey
Find useful and relevant information for your journey from Sioux Falls to Durham. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.
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Find flights from Sioux Falls to Durham, based on your preferred cabin class, be it economy, premium economy, business, or first class.
Sioux Falls and Durham flights
Browse other Sioux Falls and Durham flight options. Last updated on April 18, 2026.
Other flights from Sioux Falls
Browse through other flights departing from Sioux Falls. Flights are based on user searches made on Cheapflights and were last updated on April 18, 2026.
Popular flight searches
Check out other popular destinations found by fellow travelers in 2026
Sioux Falls to Durham flights
Consider these flights traveling from Sioux Falls to Durham.
Top 3 airlines flying from Sioux Falls to Durham
Discover the top 3 airlines that operate flights from Sioux Falls to Durham. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated April 18, 2026.
| Airline | Cheapest | Average | Flexibility | On-time |
|---|---|---|---|---|
| Cheapest$236 | Average$511 | FlexibilityNo cancel fee | On-time69% | |
| Cheapest$258 | Average$368 | FlexibilityNo cancel fee | On-time71% | |
| Cheapest$258 | Average$340 | FlexibilityNo cancel fee | On-timeN/A |