$129+ Cheap flights from Sioux Falls (FSD) to Durham, NC
This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 7/29. Fares are subject to change and may not be available on all flights or dates of travel.
FSD — RDU
Aug 10 — Aug 171
Round-trip
1 adult, Economy
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Cheapest flights from Sioux Falls to DurhamExplore the most affordable flight options available from Sioux Falls to Durham. Find the lowest fares from popular airlines and budget airlines, with prices last updated on July 11, 2026.
Explore the most affordable flight options available from Sioux Falls to Durham. Find the lowest fares from popular airlines and budget airlines, with prices last updated on July 11, 2026.
This Expedia deal was found by Cheapflights users on 7/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Expedia is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 8/38:08 pm
FSD
- RDU
1 stop14h 23m
Frontier
Wed 8/512:26 pm
RDU
- FSD
1 stop7h 57m
Frontier
Deal found 7/6![Frontier logo]()
$228
This American Airlines deal was found by Cheapflights users on 7/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 9/96:00 am
FSD
- RDU
1 stop9h 05m
American Airlines
Sat 9/126:00 am
RDU
- FSD
1 stop6h 36m
American Airlines
Deal found 7/9![American Airlines logo]()
$311
This Kiwi.com deal was found by Cheapflights users on 7/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 8/67:10 pm
FSD
- RDU
1 stop12h 50m
Multiple Airlines
Thu 8/136:14 pm
RDU
- FSD
2 stops40h 29m
Multiple Airlines
Deal found 7/7![Multiple Airlines logo]()
$318
This American Airlines deal was found by Cheapflights users on 7/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 8/44:54 pm
FSD
- RDU
1 stop5h 48m
American Airlines
Mon 8/108:17 pm
RDU
- FSD
1 stop5h 13m
American Airlines
Deal found 7/6![American Airlines logo]()
$319
This Delta deal was found by Cheapflights users on 7/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 10/65:00 pm
FSD
- RDU
1 stop5h 57m
Delta
Sat 10/103:30 pm
RDU
- FSD
1 stop5h 26m
Delta
Deal found 7/8![Delta logo]()
$325
This Delta deal was found by Cheapflights users on 7/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 9/245:30 am
FSD
- RDU
1 stop6h 03m
Delta
Sun 9/276:00 am
RDU
- FSD
1 stop5h 19m
Delta
Deal found 7/6![Delta logo]()
$333
This American Airlines deal was found by Cheapflights users on 7/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 7/254:43 pm
FSD
- RDU
1 stop5h 35m
American Airlines
Sat 8/17:07 pm
RDU
- FSD
1 stop6h 11m
American Airlines
Deal found 7/6![American Airlines logo]()
$344
Best flights from Sioux Falls to DurhamDiscover carefully curated flight deals from Sioux Falls to Durham that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated July 11, 2026.
Discover carefully curated flight deals from Sioux Falls to Durham that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated July 11, 2026.
This Expedia deal was found by Cheapflights users on 7/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Expedia is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 8/38:08 pm
FSD
- RDU
1 stop14h 23m
Frontier
Wed 8/512:26 pm
RDU
- FSD
1 stop7h 57m
Frontier
Deal found 7/6![Frontier logo]()
$228
This American Airlines deal was found by Cheapflights users on 7/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 9/96:00 am
FSD
- RDU
1 stop9h 05m
American Airlines
Sat 9/126:00 am
RDU
- FSD
1 stop6h 36m
American Airlines
Deal found 7/10![American Airlines logo]()
$311
This United Airlines deal was found by Cheapflights users on 7/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 8/77:35 am
FSD
- RDU
1 stop5h 26m
United Airlines
Thu 8/136:25 am
RDU
- FSD
1 stop5h 04m
United Airlines
Deal found 7/8![United Airlines logo]()
$319
This Delta deal was found by Cheapflights users on 7/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 10/65:00 pm
FSD
- RDU
1 stop5h 57m
Delta
Sat 10/103:30 pm
RDU
- FSD
1 stop5h 26m
Delta
Deal found 7/10![Delta logo]()
$325
This American Airlines deal was found by Cheapflights users on 7/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 8/136:24 am
FSD
- RDU
1 stop7h 53m
American Airlines
Thu 8/202:07 pm
RDU
- FSD
1 stop9h 00m
American Airlines
Deal found 7/9![American Airlines logo]()
$319
This Delta deal was found by Cheapflights users on 7/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 9/245:30 am
FSD
- RDU
1 stop4h 56m
Delta
Sun 9/276:00 am
RDU
- FSD
1 stop7h 19m
Delta
Deal found 7/9![Delta logo]()
$333
This American Airlines deal was found by Cheapflights users on 7/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 8/44:54 pm
FSD
- RDU
1 stop5h 48m
American Airlines
Mon 8/103:36 pm
RDU
- FSD
2 stops9h 54m
American Airlines
Deal found 7/6![American Airlines logo]()
$324
Last-minute flights from Sioux Falls to DurhamDiscover last-minute flight deals from Sioux Falls to Durham. Data last updated July 11, 2026 and is based on user searches.
Discover last-minute flight deals from Sioux Falls to Durham. Data last updated July 11, 2026 and is based on user searches.
This American Airlines deal was found by Cheapflights users on 7/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 7/234:43 pm
FSD
- RDU
1 stop6h 16m
American Airlines
Mon 7/274:53 pm
RDU
- FSD
1 stop6h 05m
American Airlines
Deal found 7/7![American Airlines logo]()
$369
This American Airlines deal was found by Cheapflights users on 7/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 7/254:43 pm
FSD
- RDU
1 stop5h 35m
American Airlines
Sat 8/17:07 pm
RDU
- FSD
1 stop6h 11m
American Airlines
Deal found 7/6![American Airlines logo]()
$344
This Expedia deal was found by Cheapflights users on 7/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Expedia is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 8/38:08 pm
FSD
- RDU
1 stop14h 23m
Frontier
Wed 8/512:26 pm
RDU
- FSD
1 stop7h 57m
Frontier
Deal found 7/6![Frontier logo]()
$228
This American Airlines deal was found by Cheapflights users on 7/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 8/44:54 pm
FSD
- RDU
1 stop5h 48m
American Airlines
Mon 8/108:17 pm
RDU
- FSD
1 stop5h 13m
American Airlines
Deal found 7/6![American Airlines logo]()
$319
This Kiwi.com deal was found by Cheapflights users on 7/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 8/67:10 pm
FSD
- RDU
1 stop12h 50m
Multiple Airlines
Thu 8/136:14 pm
RDU
- FSD
2 stops40h 29m
Multiple Airlines
Deal found 7/7![Multiple Airlines logo]()
$318
This Delta deal was found by Cheapflights users on 7/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 8/65:30 am
FSD
- RDU
1 stop6h 15m
Delta
Thu 8/136:00 am
RDU
- FSD
1 stop5h 20m
Delta
Deal found 7/7![Delta logo]()
$366
This Kiwi.com deal was found by Cheapflights users on 7/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 8/78:08 pm
FSD
- RDU
1 stop14h 23m
Multiple Airlines
Thu 8/138:56 am
RDU
- FSD
2 stops25h 11m
Multiple Airlines
Deal found 7/8![Multiple Airlines logo]()
$365
One-way flights from Sioux Falls to DurhamSearch for one-way flight options from Sioux Falls to Durham. Find affordable one-way fares based on user searches. Data last updated July 11, 2026.
Search for one-way flight options from Sioux Falls to Durham. Find affordable one-way fares based on user searches. Data last updated July 11, 2026.
This Travelocity deal was found by Cheapflights users on 7/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Travelocity is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 7/298:08 pm
FSD
- RDU
1 stop14h 23m
Frontier
Deal found 7/9![Frontier logo]()
$129
This Kiwi.com deal was found by Cheapflights users on 7/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/237:31 pm
FSD
- RDU
2 stops18h 16m
Frontier
Deal found 7/10![Frontier logo]()
$172
This Kiwi.com deal was found by Cheapflights users on 7/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 8/38:08 pm
FSD
- RDU
2 stops35h 03m
Frontier
Deal found 7/9![Frontier logo]()
$212
This Kiwi.com deal was found by Cheapflights users on 7/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 7/318:08 pm
FSD
- RDU
2 stops35h 03m
Frontier
Deal found 7/9![Frontier logo]()
$213
This Kiwi.com deal was found by Cheapflights users on 7/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 7/306:36 pm
FSD
- RDU
3 stops52h 27m
Multiple Airlines
Deal found 7/9![Multiple Airlines logo]()
$263
This Kiwi.com deal was found by Cheapflights users on 7/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 8/67:10 pm
FSD
- RDU
3 stops51h 54m
Multiple Airlines
Deal found 7/6![Multiple Airlines logo]()
$288
This United Airlines deal was found by Cheapflights users on 7/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 8/27:35 am
FSD
- RDU
1 stop5h 26m
United Airlines
Deal found 7/9![United Airlines logo]()
$304
This Kiwi.com deal was found by Cheapflights users on 7/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 7/318:08 pm
FSD
- RDU
3 stops19h 11m
Multiple Airlines
Deal found 7/9![Multiple Airlines logo]()
$305
This American Airlines deal was found by Cheapflights users on 7/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 8/412:00 pm
FSD
- RDU
2 stops10h 55m
American Airlines
Deal found 7/9![American Airlines logo]()
$309
This Kiwi.com deal was found by Cheapflights users on 7/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 8/26:36 pm
FSD
- RDU
3 stops50h 13m
Multiple Airlines
Deal found 7/6![Multiple Airlines logo]()
$342
Find flight deals from Sioux Falls to Durham
Keep the following information in mind while searching for Sioux Falls to Durham flight deals. Data was last updated July 11, 2026.
Most accurate provider | FlightHub 3 stars |
|---|---|
Most trusted provider | FlightHub 3 stars |
Round-trip from | $228 (Expedia) |
One-way from | $129 (Travelocity) |
Popular in | June |
Cheapest in | October |
Average price | $398 |
Cheapflights Fare Finder
Customize your flight search to find flights from Sioux Falls to Durham that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated July 11, 2026.
Use the filters below to find and compare flights from Sioux Falls to Durham that are best for you.
Fly from
Fly to
Route
Depart
Return
Cheapest round-trip
Sioux FallsRaleigh
FSD - RDU
FSDRDU
Sioux Falls Joe Foss Field
Mon 8/3
8:08 pm-11:31 am
1 stop14h 23m
Raleigh-Durham
Wed 8/5
12:26 pm-7:23 pm
1 stop7h 57m
$228
Sioux FallsRaleigh
FSD - RDU
FSDRDU
Sioux Falls Joe Foss Field
Wed 9/9
6:00 am-4:05 pm
1 stop9h 05m
Raleigh-Durham
Sat 9/12
6:00 am-11:36 am
1 stop6h 36m
$311
Quickest round-trip
Sioux FallsRaleigh
FSD - RDU
FSDRDU
Sioux Falls Joe Foss Field
Fri 8/7
7:35 am-2:01 pm
1 stop5h 26m
Raleigh-Durham
Thu 8/13
6:25 am-10:29 am
1 stop5h 04m
$319
Sioux FallsRaleigh
FSD - RDU
FSDRDU
Sioux Falls Joe Foss Field
Thu 8/13
6:24 am-3:17 pm
1 stop7h 53m
Raleigh-Durham
Thu 8/20
2:07 pm-10:07 pm
1 stop9h 00m
$319
Sioux FallsRaleigh
FSD - RDU
FSDRDU
Sioux Falls Joe Foss Field
Tue 8/4
4:54 pm-11:42 pm
1 stop5h 48m
Raleigh-Durham
Mon 8/10
3:36 pm-12:30 am
2 stops9h 54m
$324
Sioux FallsRaleigh
FSD - RDU
FSDRDU
Sioux Falls Joe Foss Field
Tue 10/6
5:00 pm-11:57 pm
1 stop5h 57m
Raleigh-Durham
Sat 10/10
3:30 pm-7:56 pm
1 stop5h 26m
$325
Sioux FallsRaleigh
FSD - RDU
FSDRDU
Sioux Falls Joe Foss Field
Thu 9/24
5:30 am-11:26 am
1 stop4h 56m
Raleigh-Durham
Sun 9/27
6:00 am-12:19 pm
1 stop7h 19m
$333
Cheapest one-way
Sioux FallsRaleigh
FSD - RDU
FSDRDU
Sioux Falls Joe Foss Field
Fri 10/23
7:31 pm-2:47 pm
2 stops18h 16m
$172
Sioux FallsRaleigh
FSD - RDU
FSDRDU
Sioux Falls Joe Foss Field
Thu 8/6
7:10 pm-12:04 am
3 stops51h 54m
$288
Quickest one-way
Sioux FallsRaleigh
FSD - RDU
FSDRDU
Sioux Falls Joe Foss Field
Thu 7/30
11:16 am-5:27 pm
1 stop5h 11m
$304
Showing 1-10 of 17 resultsSorted by cheapest first
Best time to book a flight from Sioux Falls to Durham
Have a flexible travel schedule? Discover the best time to fly to Durham from Sioux Falls with our price prediction graph.
FSD-RDU
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.
Cheapflights Insights
Everything you need to know about your flight from Sioux Falls to Durham
FSD-DU8
FSD-RDU
No data available for this route at this time. Please check back soon.
Reviews of airlines servicing Durham
Get insights into the airlines that provide service to Durham. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Durham. Reviews last updated July 11, 2026.
See what other customers who have flown with Delta,United Airlines, andAmerican Airlines from Sioux Falls to Durham have to say. You can also see how each airline compares in terms of entertainment options, comfort, food, crew/service, and boarding process.
Entertainment
7.8
Comfort
7.8
Boarding
8.1
Food
7.2
Crew
8.5
Overall
7.8
Reviews
1 / 20
10.0
ExcellentAnonymous,May 2026
SEA - KOA
Entertainment
7.8
Comfort
7.8
Boarding
8.1
Food
7.2
Crew
8.5
Overall
7.8
Reviews
1 / 20
10.0
ExcellentAnonymous,May 2026
SEA - KOA
Entertainment
7.8
Comfort
7.8
Boarding
8.1
Food
7.2
Crew
8.5
Overall
7.8
Reviews
1 / 20
10.0
ExcellentAnonymous,May 2026
SEA - KOA
Entertainment
7.8
Comfort
7.8
Boarding
8.1
Food
7.2
Crew
8.5
Overall
7.8
Reviews
1 / 20
10.0
ExcellentAnonymous,May 2026
SEA - KOA
Related info for your journey
Find useful and relevant information for your journey from Sioux Falls to Durham. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.
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Sioux Falls and Durham flights
Browse other Sioux Falls and Durham flight options. Last updated on July 11, 2026.
Other flights from Sioux Falls
Browse through other flights departing from Sioux Falls. Flights are based on user searches made on Cheapflights and were last updated on July 11, 2026.
Popular flight searches
Check out other popular destinations found by fellow travelers in 2026
Sioux Falls to Durham flights
Consider these flights traveling from Sioux Falls to Durham.
Top 3 airlines flying from Sioux Falls to Durham
Discover the top 3 airlines that operate flights from Sioux Falls to Durham. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated July 11, 2026.
| Airline | Cheapest | Average | Flexibility | On-time |
|---|---|---|---|---|
| Cheapest$258 | Average$340 | FlexibilityNo cancel fee | On-time71% | |
| Cheapest$258 | Average$358 | FlexibilityNo cancel fee | On-timeN/A | |
| Cheapest$307 | Average$473 | FlexibilityNo cancel fee | On-time69% |