$129+ Cheap flights from Sioux Falls (FSD) to Durham, NC
This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 7/13. Fares are subject to change and may not be available on all flights or dates of travel.
FSD — RDU
Jul 28 — Aug 41
Round-trip
1 adult, Economy
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Cheapest flights from Sioux Falls to DurhamExplore the most affordable flight options available from Sioux Falls to Durham. Find the lowest fares from popular airlines and budget airlines, with prices last updated on June 28, 2026.
Explore the most affordable flight options available from Sioux Falls to Durham. Find the lowest fares from popular airlines and budget airlines, with prices last updated on June 28, 2026.
This Expedia deal was found by Cheapflights users on 6/24. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Expedia is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 8/58:08 pm
FSD
- RDU
1 stop14h 23m
Frontier
Wed 8/1212:26 pm
RDU
- FSD
1 stop7h 57m
Frontier
Deal found 6/24![Frontier logo]()
$210
This Expedia deal was found by Cheapflights users on 6/24. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Expedia is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 8/148:08 pm
FSD
- RDU
1 stop14h 23m
Frontier
Mon 8/1712:26 pm
RDU
- FSD
1 stop7h 57m
Frontier
Deal found 6/24![Frontier logo]()
$246
This Expedia deal was found by Cheapflights users on 6/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Expedia is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 7/38:14 pm
FSD
- RDU
1 stop14h 17m
Frontier
Wed 7/1512:26 pm
RDU
- FSD
1 stop7h 57m
Frontier
Deal found 6/25![Frontier logo]()
$273
This American Airlines deal was found by Cheapflights users on 6/24. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 9/96:00 am
FSD
- RDU
1 stop9h 05m
American Airlines
Sat 9/126:00 am
RDU
- FSD
1 stop6h 41m
American Airlines
Deal found 6/24![American Airlines logo]()
$311
This American Airlines deal was found by Cheapflights users on 6/24. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 9/117:00 am
FSD
- RDU
1 stop6h 03m
American Airlines
Mon 9/147:47 pm
RDU
- FSD
1 stop5h 33m
American Airlines
Deal found 6/24![American Airlines logo]()
$319
This American Airlines deal was found by Cheapflights users on 6/24. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 8/2812:57 pm
FSD
- RDU
1 stop7h 19m
American Airlines
Mon 8/318:17 pm
RDU
- FSD
1 stop5h 13m
American Airlines
Deal found 6/24![American Airlines logo]()
$324
This Delta deal was found by Cheapflights users on 6/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 10/65:25 am
FSD
- RDU
1 stop7h 42m
Delta
Sat 10/106:00 am
RDU
- FSD
1 stop5h 05m
Delta
Deal found 6/23![Delta logo]()
$325
This Delta deal was found by Cheapflights users on 6/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 12/214:09 pm
FSD
- RDU
1 stop6h 44m
Delta
Sat 12/266:00 am
RDU
- FSD
1 stop5h 05m
Delta
Deal found 6/25![Delta logo]()
$329
This Delta deal was found by Cheapflights users on 6/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 12/214:09 pm
FSD
- RDU
1 stop6h 44m
Delta
Mon 12/286:00 am
RDU
- FSD
1 stop7h 11m
Delta
Deal found 6/25![Delta logo]()
$333
This American Airlines deal was found by Cheapflights users on 6/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 7/36:00 am
FSD
- RDU
1 stop6h 27m
American Airlines
Wed 7/87:08 am
RDU
- FSD
1 stop5h 22m
American Airlines
Deal found 6/23![American Airlines logo]()
$340
Best flights from Sioux Falls to DurhamDiscover carefully curated flight deals from Sioux Falls to Durham that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated June 28, 2026.
Discover carefully curated flight deals from Sioux Falls to Durham that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated June 28, 2026.
This American Airlines deal was found by Cheapflights users on 6/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 9/912:56 pm
FSD
- RDU
2 stops9h 01m
American Airlines
Sat 9/123:36 pm
RDU
- FSD
2 stops9h 44m
American Airlines
Deal found 6/26![American Airlines logo]()
$321
This Delta deal was found by Cheapflights users on 6/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 10/65:25 am
FSD
- RDU
1 stop7h 42m
Delta
Sat 10/106:00 am
RDU
- FSD
1 stop5h 05m
Delta
Deal found 6/25![Delta logo]()
$325
This United Airlines deal was found by Cheapflights users on 6/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/17:50 am
FSD
- RDU
1 stop4h 59m
United Airlines
Mon 10/55:01 pm
RDU
- FSD
1 stop7h 10m
United Airlines
Deal found 6/23![United Airlines logo]()
$350
This American Airlines deal was found by Cheapflights users on 6/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 8/2812:57 pm
FSD
- RDU
1 stop7h 19m
American Airlines
Mon 8/318:17 pm
RDU
- FSD
1 stop5h 13m
American Airlines
Deal found 6/27![American Airlines logo]()
$324
This Delta deal was found by Cheapflights users on 6/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 12/214:09 pm
FSD
- RDU
1 stop6h 44m
Delta
Mon 12/286:00 am
RDU
- FSD
1 stop7h 11m
Delta
Deal found 6/25![Delta logo]()
$333
This United Airlines deal was found by Cheapflights users on 6/24. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 8/297:47 am
FSD
- RDU
1 stop5h 30m
United Airlines
Wed 9/211:29 am
RDU
- FSD
1 stop7h 29m
United Airlines
Deal found 6/24![United Airlines logo]()
$401
This Delta deal was found by Cheapflights users on 6/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 7/75:20 am
FSD
- RDU
1 stop5h 15m
Delta
Sat 7/187:07 pm
RDU
- FSD
1 stop4h 45m
Delta
Deal found 6/27![Delta logo]()
$378
This American Airlines deal was found by Cheapflights users on 6/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 10/65:59 pm
FSD
- RDU
1 stop4h 34m
American Airlines
Sat 10/104:19 pm
RDU
- FSD
2 stops6h 58m
American Airlines
Deal found 6/23![American Airlines logo]()
$398
This American Airlines deal was found by Cheapflights users on 6/24. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 8/56:00 am
FSD
- RDU
2 stops7h 46m
American Airlines
Wed 8/1212:09 pm
RDU
- FSD
2 stops8h 50m
American Airlines
Deal found 6/24![American Airlines logo]()
$403
Last-minute flights from Sioux Falls to DurhamDiscover last-minute flight deals from Sioux Falls to Durham. Data last updated June 28, 2026 and is based on user searches.
Discover last-minute flight deals from Sioux Falls to Durham. Data last updated June 28, 2026 and is based on user searches.
This Expedia deal was found by Cheapflights users on 6/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Expedia is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 7/38:14 pm
FSD
- RDU
1 stop14h 17m
Frontier
Wed 7/1512:26 pm
RDU
- FSD
1 stop7h 57m
Frontier
Deal found 6/25![Frontier logo]()
$273
This American Airlines deal was found by Cheapflights users on 6/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 7/36:00 am
FSD
- RDU
1 stop6h 27m
American Airlines
Wed 7/87:08 am
RDU
- FSD
1 stop5h 22m
American Airlines
Deal found 6/23![American Airlines logo]()
$340
This Delta deal was found by Cheapflights users on 6/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 7/65:12 am
FSD
- RDU
1 stop4h 21m
Delta
Sat 7/187:07 pm
RDU
- FSD
1 stop4h 45m
Delta
Deal found 6/27![Delta logo]()
$406
This Delta deal was found by Cheapflights users on 6/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 7/75:20 am
FSD
- RDU
1 stop5h 15m
Delta
Sat 7/187:07 pm
RDU
- FSD
1 stop4h 45m
Delta
Deal found 6/27![Delta logo]()
$378
This American Airlines deal was found by Cheapflights users on 6/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 7/712:00 pm
FSD
- RDU
2 stops10h 58m
American Airlines
Sat 7/188:10 pm
RDU
- FSD
1 stop5h 08m
American Airlines
Deal found 6/27![American Airlines logo]()
$428
This Delta deal was found by Cheapflights users on 6/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 7/115:20 am
FSD
- RDU
1 stop5h 18m
Delta
Sat 7/187:07 pm
RDU
- FSD
1 stop4h 45m
Delta
Deal found 6/25![Delta logo]()
$359
This Delta deal was found by Cheapflights users on 6/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 7/115:20 am
FSD
- RDU
1 stop5h 18m
Delta
Wed 7/157:10 pm
RDU
- FSD
1 stop4h 56m
Delta
Deal found 6/26![Delta logo]()
$385
One-way flights from Sioux Falls to DurhamSearch for one-way flight options from Sioux Falls to Durham. Find affordable one-way fares based on user searches. Data last updated June 28, 2026.
Search for one-way flight options from Sioux Falls to Durham. Find affordable one-way fares based on user searches. Data last updated June 28, 2026.
This Expedia deal was found by Cheapflights users on 6/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Expedia is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 7/138:08 pm
FSD
- RDU
1 stop14h 23m
Frontier
Deal found 6/26![Frontier logo]()
$129
This Kiwi.com deal was found by Cheapflights users on 6/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 7/208:08 pm
FSD
- RDU
2 stops20h 21m
Frontier
Deal found 6/26![Frontier logo]()
$201
This Kiwi.com deal was found by Cheapflights users on 6/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 7/116:14 pm
FSD
- RDU
2 stops42h 05m
Multiple Airlines
Deal found 6/26![Multiple Airlines logo]()
$271
This Kiwi.com deal was found by Cheapflights users on 6/24. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 7/196:36 pm
FSD
- RDU
1 stop13h 24m
Multiple Airlines
Deal found 6/24![Multiple Airlines logo]()
$275
This Kiwi.com deal was found by Cheapflights users on 6/24. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 7/96:36 pm
FSD
- RDU
3 stops52h 27m
Multiple Airlines
Deal found 6/24![Multiple Airlines logo]()
$299
This deal was found by Cheapflights users on 6/24. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 9/277:50 am
FSD
- RDU
1 stop4h 59m
United Airlines
Deal found 6/24![United Airlines logo]()
$348
This KAYAK deal was found by Cheapflights users on 6/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure KAYAK is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 7/26:00 am
FSD
- RDU
1 stop8h 59m
American Airlines
Deal found 6/25![American Airlines logo]()
$350
This Kiwi.com deal was found by Cheapflights users on 6/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 7/126:36 pm
FSD
- RDU
3 stops45h 33m
Multiple Airlines
Deal found 6/27![Multiple Airlines logo]()
$365
Find flight deals from Sioux Falls to Durham
Keep the following information in mind while searching for Sioux Falls to Durham flight deals. Data was last updated June 28, 2026.
Most accurate provider | FlightHub 3 stars |
|---|---|
Most trusted provider | FlightHub 3 stars |
Round-trip from | $210 (Expedia) |
One-way from | $129 (Expedia) |
Popular in | June |
Cheapest in | October |
Average price | $626 |
Cheapflights Fare Finder
Customize your flight search to find flights from Sioux Falls to Durham that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated June 28, 2026.
Use the filters below to find and compare flights from Sioux Falls to Durham that are best for you.
Fly from
Fly to
Route
Depart
Return
Cheapest round-trip
Sioux FallsRaleigh
FSD - RDU
FSDRDU
Sioux Falls Joe Foss Field
Wed 9/9
12:56 pm-10:57 pm
2 stops9h 01m
Raleigh-Durham
Sat 9/12
3:36 pm-12:20 am
2 stops9h 44m
$321
Sioux FallsRaleigh
FSD - RDU
FSDRDU
Sioux Falls Joe Foss Field
Fri 8/28
12:57 pm-9:16 pm
1 stop7h 19m
Raleigh-Durham
Mon 8/31
8:17 pm-12:30 am
1 stop5h 13m
$324
Sioux FallsRaleigh
FSD - RDU
FSDRDU
Sioux Falls Joe Foss Field
Tue 10/6
5:25 am-2:07 pm
1 stop7h 42m
Raleigh-Durham
Sat 10/10
6:00 am-10:05 am
1 stop5h 05m
$325
Sioux FallsRaleigh
FSD - RDU
FSDRDU
Sioux Falls Joe Foss Field
Mon 12/21
4:09 pm-11:53 pm
1 stop6h 44m
Raleigh-Durham
Mon 12/28
6:00 am-12:11 pm
1 stop7h 11m
$333
Sioux FallsRaleigh
FSD - RDU
FSDRDU
Sioux Falls Joe Foss Field
Thu 10/1
7:50 am-1:49 pm
1 stop4h 59m
Raleigh-Durham
Mon 10/5
5:01 pm-11:11 pm
1 stop7h 10m
$350
Quickest round-trip
Sioux FallsRaleigh
FSD - RDU
FSDRDU
Sioux Falls Joe Foss Field
Tue 7/7
5:20 am-11:35 am
1 stop5h 15m
Raleigh-Durham
Sat 7/18
7:07 pm-10:52 pm
1 stop4h 45m
$378
Sioux FallsRaleigh
FSD - RDU
FSDRDU
Sioux Falls Joe Foss Field
Tue 10/6
5:59 pm-11:33 pm
1 stop4h 34m
Raleigh-Durham
Sat 10/10
4:19 pm-10:17 pm
2 stops6h 58m
$398
Sioux FallsRaleigh
FSD - RDU
FSDRDU
Sioux Falls Joe Foss Field
Sat 8/29
7:47 am-2:17 pm
1 stop5h 30m
Raleigh-Durham
Wed 9/2
11:29 am-5:58 pm
1 stop7h 29m
$401
Sioux FallsRaleigh
FSD - RDU
FSDRDU
Sioux Falls Joe Foss Field
Wed 8/5
6:00 am-2:46 pm
2 stops7h 46m
Raleigh-Durham
Wed 8/12
12:09 pm-7:59 pm
2 stops8h 50m
$403
Cheapest one-way
Sioux FallsRaleigh
FSD - RDU
FSDRDU
Sioux Falls Joe Foss Field
Mon 7/13
8:08 pm-11:31 am
1 stop14h 23m
$129
Showing 1-10 of 18 resultsSorted by cheapest first
Best time to book a flight from Sioux Falls to Durham
Have a flexible travel schedule? Discover the best time to fly to Durham from Sioux Falls with our price prediction graph.
FSD-RDU
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.
Cheapflights Insights
Everything you need to know about your flight from Sioux Falls to Durham
FSD-DU8
FSD-RDU
No data available for this route at this time. Please check back soon.
Reviews of airlines servicing Durham
Get insights into the airlines that provide service to Durham. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Durham. Reviews last updated June 28, 2026.
See what other customers who have flown with Delta,United Airlines, andAmerican Airlines from Sioux Falls to Durham have to say. You can also see how each airline compares in terms of entertainment options, comfort, food, crew/service, and boarding process.
Entertainment
7.8
Overall
7.8
Crew
8.5
Food
7.2
Comfort
7.8
Boarding
8.1
Reviews
1 / 20
10.0
ExcellentAnonymous,May 2026
SEA - KOA
Entertainment
7.8
Overall
7.8
Crew
8.5
Food
7.2
Comfort
7.8
Boarding
8.1
Reviews
1 / 20
10.0
ExcellentAnonymous,May 2026
SEA - KOA
Entertainment
7.8
Overall
7.8
Crew
8.5
Food
7.2
Comfort
7.8
Boarding
8.1
Reviews
1 / 20
10.0
ExcellentAnonymous,May 2026
SEA - KOA
Entertainment
7.8
Overall
7.8
Crew
8.5
Food
7.2
Comfort
7.8
Boarding
8.1
Reviews
1 / 20
10.0
ExcellentAnonymous,May 2026
SEA - KOA
Related info for your journey
Find useful and relevant information for your journey from Sioux Falls to Durham. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.
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Complete your trip
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Find flights from Sioux Falls to Durham, based on your preferred cabin class, be it economy, premium economy, business, or first class.
Sioux Falls and Durham flights
Browse other Sioux Falls and Durham flight options. Last updated on June 28, 2026.
Other flights from Sioux Falls
Browse through other flights departing from Sioux Falls. Flights are based on user searches made on Cheapflights and were last updated on June 28, 2026.
Popular flight searches
Check out other popular destinations found by fellow travelers in 2026
Sioux Falls to Durham flights
Consider these flights traveling from Sioux Falls to Durham.
Top 3 airlines flying from Sioux Falls to Durham
Discover the top 3 airlines that operate flights from Sioux Falls to Durham. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated June 28, 2026.
| Airline | Cheapest | Average | Flexibility | On-time |
|---|---|---|---|---|
| Cheapest$258 | Average$340 | FlexibilityNo cancel fee | On-time71% | |
| Cheapest$258 | Average$358 | FlexibilityNo cancel fee | On-timeN/A | |
| Cheapest$307 | Average$473 | FlexibilityNo cancel fee | On-time69% |