HomeSearch by dateVacation packagesHotelsFlight dealsCar rentalTravel tips & news
Durham

$104+ Cheap flights from Sioux Falls (FSD) to Durham, NC

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 4/24. Fares are subject to change and may not be available on all flights or dates of travel.
FSD — RDU
Apr 16 — Apr 231
Thu 4/16
Thu 4/23
1 adult, Economy
We work with more than 300 partners to bring you better travel deals

Find cheap flights from Sioux Falls to Durham with Cheapflights

1. Tell us where you want to go

Enter your travel information like dates, passengers, trip type (one-way or round trip), and preferred cabin class then click “Find deals”

2. Select your favorite providers

We find the providers serving your travel needs. Choose up to four travel providers to compare side-by-side for flights, hotels, or car rentals.

3. Compare prices and book

Review each provider’s pricing and select the best option for you! Book through your favorite provider’s website for a seamless experience.

Cheap flight deals from Sioux Falls to Durham

Cheapest flights from Sioux Falls to Durham
Explore the most affordable flight options available from Sioux Falls to Durham. Find the lowest fares from popular airlines and budget airlines, with prices last updated on March 17, 2026.

This Mytrip deal was found by Cheapflights users on 3/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Mytrip is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 4/248:06 pm
FSD
-
RDU
1 stop23h 58m
Frontier
Sun 4/269:49 pm
RDU
-
FSD
1 stop22h 32m
Frontier
Deal found 3/14$209
This Booking.com deal was found by Cheapflights users on 3/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Booking.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 5/84:07 pm
FSD
-
RDU
1 stop18h 24m
Frontier
Sun 5/1012:26 pm
RDU
-
FSD
1 stop27h 56m
Frontier
Deal found 3/12$212
This American Airlines deal was found by Cheapflights users on 3/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 9/96:00 pm
FSD
-
RDU
1 stop4h 27m
American Airlines
Sat 9/122:19 pm
RDU
-
FSD
1 stop8h 36m
American Airlines
Deal found 3/16$311
This American Airlines deal was found by Cheapflights users on 3/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 5/81:41 pm
FSD
-
RDU
1 stop7h 56m
American Airlines
Sat 5/163:50 pm
RDU
-
FSD
1 stop7h 16m
American Airlines
Deal found 3/13$315
This American Airlines deal was found by Cheapflights users on 3/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 4/103:17 pm
FSD
-
RDU
1 stop7h 42m
American Airlines
Sun 4/125:45 am
RDU
-
FSD
1 stop7h 14m
American Airlines
Deal found 3/12$319
This Delta deal was found by Cheapflights users on 3/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 10/31:20 pm
FSD
-
RDU
2 stops8h 42m
Delta
Wed 10/76:40 pm
RDU
-
FSD
1 stop5h 11m
Delta
Deal found 3/15$336
This United Airlines deal was found by Cheapflights users on 3/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 5/276:37 pm
FSD
-
RDU
1 stop5h 13m
United Airlines
Mon 6/15:07 pm
RDU
-
FSD
1 stop5h 31m
United Airlines
Deal found 3/12$337
This United Airlines deal was found by Cheapflights users on 3/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 5/306:37 pm
FSD
-
RDU
1 stop5h 13m
United Airlines
Fri 6/54:22 pm
RDU
-
FSD
1 stop8h 31m
United Airlines
Deal found 3/12$339
This Kiwi.com deal was found by Cheapflights users on 3/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 4/248:06 pm
FSD
-
RDU
2 stops11h 36m
Multiple Airlines
Sun 4/269:37 pm
RDU
-
FSD
1 stop20h 44m
Multiple Airlines
Deal found 3/16$347

Find flight deals from Sioux Falls to Durham

Keep the following information in mind while searching for Sioux Falls to Durham flight deals. Data was last updated March 17, 2026.

Most accurate provider

FlightHub
3 stars

Most trusted provider

FlightHub
3 stars

Round-trip from

$209
(Mytrip)

One-way from

$104
(Kiwi.com)

Popular in

March

Cheapest in

August

Average price

$504
Provider with most accurate pricing for Sioux Falls Joe Foss Field-Raleigh-Durham flight deals.
Search Deals
Provider most trusted by Cheapflights users for Sioux Falls Joe Foss Field-Raleigh-Durham flights.
Search Deals
From Sioux Falls Joe Foss Field to Durham
Search Deals
One-way flight from Sioux Falls Joe Foss Field to Durham
Search Deals
Highest demand for flights based on searches. 15% potential increase in price ($66 potential increase over avg. RT price).
Search Deals
Cheapest flight prices on average. 4% potential price decrease ($14 potential savings vs. average RT price).
Search Deals
Average for round-trip flights in March 2026
Search Deals

Cheapflights Fare Finder

 
Customize your flight search to find flights from Sioux Falls to Durham that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated March 17, 2026.
Use the filters below to find and compare flights from Sioux Falls to Durham that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

Cheapest round-trip

Sioux FallsRaleigh

FSD - RDU

FSDRDU

Sioux Falls Joe Foss Field

Fri 3/27

4:23 pm-11:59 pm

1 stop6h 36m

Raleigh-Durham

Tue 3/31

2:40 pm-11:04 pm

2 stops9h 24m

$389

Sioux FallsRaleigh

FSD - RDU

FSDRDU

Sioux Falls Joe Foss Field

Sat 4/18

6:10 am-1:58 pm

1 stop6h 48m

Raleigh-Durham

Wed 4/22

5:25 pm-11:44 pm

1 stop7h 19m

$391

Sioux FallsRaleigh

FSD - RDU

FSDRDU

Sioux Falls Joe Foss Field

Fri 5/8

5:20 am-1:36 pm

1 stop7h 16m

Raleigh-Durham

Sat 5/16

2:50 pm-7:49 pm

1 stop5h 59m

$435
Quickest round-trip

Sioux FallsRaleigh

FSD - RDU

FSDRDU

Sioux Falls Joe Foss Field

Thu 6/11

8:15 am-2:01 pm

1 stop4h 46m

Raleigh-Durham

Fri 6/19

6:40 pm-10:46 pm

1 stop5h 06m

$451

Sioux FallsRaleigh

FSD - RDU

FSDRDU

Sioux Falls Joe Foss Field

Wed 5/20

8:19 am-5:52 pm

2 stops8h 33m

Raleigh-Durham

Sun 5/31

6:00 am-10:15 am

1 stop5h 15m

$468
Cheapest one-way

Sioux FallsRaleigh

FSD - RDU

FSDRDU

Sioux Falls Joe Foss Field

Mon 3/23

5:55 pm-6:44 pm

1 stop23h 49m

$157

Sioux FallsRaleigh

FSD - RDU

FSDRDU

Sioux Falls Joe Foss Field

Mon 4/20

6:11 pm-2:48 pm

3 stops19h 37m

$198

Sioux FallsRaleigh

FSD - RDU

FSDRDU

Sioux Falls Joe Foss Field

Wed 5/20

12:29 pm-11:58 pm

1 stop10h 29m

$257

Sioux FallsRaleigh

FSD - RDU

FSDRDU

Sioux Falls Joe Foss Field

Tue 4/21

5:00 am-4:16 pm

2 stops10h 16m

$263

Sioux FallsRaleigh

FSD - RDU

FSDRDU

Sioux Falls Joe Foss Field

Thu 5/21

7:02 pm-9:00 am

1 stop12h 58m

$305

Flights are sorted by cheapest round-trip flights first.

Deals found on 3/15

Showing 1-10 of 12 resultsSorted by cheapest first
1
2

Best time to book a flight from Sioux Falls to Durham

Have a flexible travel schedule? Discover the best time to fly to Durham from Sioux Falls with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Sioux Falls to Durham

What is the cheapest month to book a flight from Sioux Falls to Durham?

Currently, December is the cheapest month in which you can book a flight from Sioux Falls to Durham (average of $172). Flying from Sioux Falls to Durham in January is currently the most expensive (average of $454). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

Reviews of airlines servicing Durham

Get insights into the airlines that provide service to Durham. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Durham. Reviews last updated March 17, 2026.
See what other customers who have flown with Delta,United Airlines, andAmerican Airlines from Sioux Falls to Durham have to say. You can also see how each airline compares in terms of entertainment options, comfort, food, crew/service, and boarding process.
Delta
7.9
Good
8,288 reviews

Crew

8.5

Boarding

8.1

Overall

7.9

Food

7.2

Comfort

7.9

Entertainment

7.8

Reviews

1 / 20
6.0
Good

Jim,Nov 2025

AVL - ATL

The exit row seats without a seat in front are great for leg room but don’t have a fold out entertainment console so you’re forced to use the screen several feet in front of you (there is, at least, a remote). Best to bring a tablet loaded with entertainment or a book.
Delta
7.9
Good
8,288 reviews
Delta
7.9
Good
8,288 reviews

Crew

8.5

Boarding

8.1

Overall

7.9

Food

7.2

Comfort

7.9

Entertainment

7.8

Reviews

1 / 20
6.0
Good

Jim,Nov 2025

AVL - ATL

The exit row seats without a seat in front are great for leg room but don’t have a fold out entertainment console so you’re forced to use the screen several feet in front of you (there is, at least, a remote). Best to bring a tablet loaded with entertainment or a book.
United Airlines
7.4
Good
9,431 reviews
Delta
7.9
Good
8,288 reviews

Crew

8.5

Boarding

8.1

Overall

7.9

Food

7.2

Comfort

7.9

Entertainment

7.8

Reviews

1 / 20
6.0
Good

Jim,Nov 2025

AVL - ATL

The exit row seats without a seat in front are great for leg room but don’t have a fold out entertainment console so you’re forced to use the screen several feet in front of you (there is, at least, a remote). Best to bring a tablet loaded with entertainment or a book.
American Airlines
7.1
Good
11,468 reviews
Delta
7.9
Good
8,288 reviews

Crew

8.5

Boarding

8.1

Overall

7.9

Food

7.2

Comfort

7.9

Entertainment

7.8

Reviews

1 / 20
6.0
Good

Jim,Nov 2025

AVL - ATL

The exit row seats without a seat in front are great for leg room but don’t have a fold out entertainment console so you’re forced to use the screen several feet in front of you (there is, at least, a remote). Best to bring a tablet loaded with entertainment or a book.

Related info for your journey

Find useful and relevant information for your journey from Sioux Falls to Durham. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • What airport do you fly from for flights from Sioux Falls to Durham?

    For a flight from Sioux Falls to Durham, you will be flying from Joe Foss Field. Sioux Falls Joe Foss Field (FSD) is just 2.6 mi from the center of the city. Joe Foss Field is the only Sioux Falls airport and it handles 0 outbound flights to Durham per day. 3 airlines have flights to Durham from Sioux Falls Joe Foss Field on a regular basis.

  • How long is the flight from Sioux Falls to Durham?

    For as low as $389, Delta can have you in Durham from Sioux Falls in 6h 36m. The distance from Sioux Falls to Durham is about 1088 mi. When browsing for deals, the options you’ll see will be for both nonstop flights and flights with stops.

  • Can I find deals for flights from Sioux Falls to Durham that include hotel bookings?

    Yes. In addition to deals on Sioux Falls to Durham flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Sioux Falls to Durham?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Sioux Falls to Durham.

  • Can I find deals for business class flights from Sioux Falls to Durham?

    Yes. Cheapflights offers flight deals from Sioux Falls to Durham by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Sioux Falls to Durham?

    Currently, December is the cheapest month in which you can book a flight from Sioux Falls to Durham (average of $172). Flying from Sioux Falls to Durham in January is currently the most expensive (average of $454). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

Browse thousands of different options on Cheapflights for your next trip

Toggle through the tabs below to find thousands of options on Cheapflights for your next trip.

Top 3 airlines flying from Sioux Falls to Durham

Discover the top 3 airlines that operate flights from Sioux Falls to Durham. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated March 17, 2026.
AirlineCheapestAverageFlexibilityOn-time
American AirlinesCheapest$198Average$299FlexibilityNo cancel feeOn-time71%
United AirlinesCheapest$236Average$498FlexibilityNo cancel feeOn-time69%
DeltaCheapest$258Average$340FlexibilityNo cancel feeOn-timeN/A

100% Free

Cheapflights is completely free to use, so you can start saving the moment you arrive.

Book with Flexibility

Our users can plan ahead with confidence and find flights with no change fees

Travel Smart

Millions of people come to us for their flight needs every year. We help make travel planning easy by providing useful insights and data-driven graphs that can inform your decisions.