$134+ Cheap flights from Sioux Falls (FSD) to Durham, NC
This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 6/30. Fares are subject to change and may not be available on all flights or dates of travel.
FSD — RDU
Jul 13 — Jul 201
Round-trip
1 adult, Economy
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Cheapest flights from Sioux Falls to DurhamExplore the most affordable flight options available from Sioux Falls to Durham. Find the lowest fares from popular airlines and budget airlines, with prices last updated on June 13, 2026.
Explore the most affordable flight options available from Sioux Falls to Durham. Find the lowest fares from popular airlines and budget airlines, with prices last updated on June 13, 2026.
This Delta deal was found by Cheapflights users on 6/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 9/96:25 am
FSD
- RDU
1 stop6h 36m
Delta
Sat 9/124:50 pm
RDU
- FSD
1 stop6h 19m
Delta
Deal found 6/9![Delta logo]()
$311
This Delta deal was found by Cheapflights users on 6/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 7/35:12 am
FSD
- RDU
1 stop4h 21m
Delta
Wed 7/87:10 pm
RDU
- FSD
1 stop4h 56m
Delta
Deal found 6/11![Delta logo]()
$315
This American Airlines deal was found by Cheapflights users on 6/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 9/912:56 pm
FSD
- RDU
2 stops9h 01m
American Airlines
Sat 9/126:00 am
RDU
- FSD
1 stop7h 16m
American Airlines
Deal found 6/10![American Airlines logo]()
$316
This American Airlines deal was found by Cheapflights users on 6/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 7/36:00 am
FSD
- RDU
2 stops8h 25m
American Airlines
Wed 7/83:07 pm
RDU
- FSD
2 stops10h 11m
American Airlines
Deal found 6/10![American Airlines logo]()
$325
This Booking.com deal was found by Cheapflights users on 6/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Booking.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 6/248:14 pm
FSD
- RDU
1 stop14h 17m
Frontier
Wed 7/2212:26 pm
RDU
- FSD
1 stop7h 57m
Frontier
Deal found 6/8![Frontier logo]()
$327
This United Airlines deal was found by Cheapflights users on 6/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 8/17:35 am
FSD
- RDU
1 stop5h 26m
United Airlines
Sat 8/85:12 pm
RDU
- FSD
1 stop7h 19m
United Airlines
Deal found 6/10![United Airlines logo]()
$339
This Delta deal was found by Cheapflights users on 6/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 7/215:20 am
FSD
- RDU
1 stop6h 22m
Delta
Thu 7/306:59 pm
RDU
- FSD
1 stop5h 07m
Delta
Deal found 6/12![Delta logo]()
$359
This American Airlines deal was found by Cheapflights users on 6/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 7/147:06 am
FSD
- RDU
2 stops9h 30m
American Airlines
Wed 7/223:07 pm
RDU
- FSD
2 stops10h 11m
American Airlines
Deal found 6/12![American Airlines logo]()
$378
This Delta deal was found by Cheapflights users on 6/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 8/15:20 am
FSD
- RDU
1 stop6h 22m
Delta
Sat 8/86:58 pm
RDU
- FSD
1 stop4h 53m
Delta
Deal found 6/13![Delta logo]()
$387
Best flights from Sioux Falls to DurhamDiscover carefully curated flight deals from Sioux Falls to Durham that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated June 13, 2026.
Discover carefully curated flight deals from Sioux Falls to Durham that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated June 13, 2026.
This Delta deal was found by Cheapflights users on 6/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 10/65:15 am
FSD
- RDU
1 stop4h 22m
Delta
Sat 10/106:00 am
RDU
- FSD
1 stop5h 05m
Delta
Deal found 6/8![Delta logo]()
$311
This American Airlines deal was found by Cheapflights users on 6/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 7/76:00 am
FSD
- RDU
1 stop6h 27m
American Airlines
Wed 7/153:07 pm
RDU
- FSD
2 stops10h 11m
American Airlines
Deal found 6/12![American Airlines logo]()
$320
This United Airlines deal was found by Cheapflights users on 6/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 8/17:35 am
FSD
- RDU
1 stop5h 26m
United Airlines
Sat 8/85:12 pm
RDU
- FSD
1 stop7h 19m
United Airlines
Deal found 6/10![United Airlines logo]()
$339
This American Airlines deal was found by Cheapflights users on 6/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 7/34:43 pm
FSD
- RDU
1 stop6h 19m
American Airlines
Wed 7/83:07 pm
RDU
- FSD
2 stops10h 11m
American Airlines
Deal found 6/10![American Airlines logo]()
$320
This Delta deal was found by Cheapflights users on 6/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 8/15:20 am
FSD
- RDU
1 stop6h 22m
Delta
Sat 8/86:58 pm
RDU
- FSD
1 stop4h 53m
Delta
Deal found 6/13![Delta logo]()
$387
This United Airlines deal was found by Cheapflights users on 6/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 8/291:33 pm
FSD
- RDU
1 stop6h 46m
United Airlines
Tue 9/14:23 pm
RDU
- FSD
1 stop8h 21m
United Airlines
Deal found 6/8![United Airlines logo]()
$401
This United Airlines deal was found by Cheapflights users on 6/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 8/267:47 am
FSD
- RDU
1 stop5h 20m
United Airlines
Sat 8/294:23 pm
RDU
- FSD
1 stop8h 21m
United Airlines
Deal found 6/11![United Airlines logo]()
$401
Last-minute flights from Sioux Falls to DurhamDiscover last-minute flight deals from Sioux Falls to Durham. Data last updated June 13, 2026 and is based on user searches.
Discover last-minute flight deals from Sioux Falls to Durham. Data last updated June 13, 2026 and is based on user searches.
This Kiwi.com deal was found by Cheapflights users on 6/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 6/171:06 pm
FSD
- RDU
1 stop18h 53m
Multiple Airlines
Sat 6/2010:03 pm
RDU
- FSD
1 stop20h 58m
Multiple Airlines
Deal found 6/10![Multiple Airlines logo]()
$409
This United Airlines deal was found by Cheapflights users on 6/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 6/177:40 am
FSD
- RDU
1 stop5h 21m
United Airlines
Sat 6/2010:45 am
RDU
- FSD
1 stop8h 10m
United Airlines
Deal found 6/10![United Airlines logo]()
$423
This American Airlines deal was found by Cheapflights users on 6/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 6/177:02 am
FSD
- RDU
2 stops9h 33m
American Airlines
Sat 6/206:03 pm
RDU
- FSD
1 stop7h 22m
American Airlines
Deal found 6/10![American Airlines logo]()
$428
This Booking.com deal was found by Cheapflights users on 6/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Booking.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 6/248:14 pm
FSD
- RDU
1 stop14h 17m
Frontier
Wed 7/2212:26 pm
RDU
- FSD
1 stop7h 57m
Frontier
Deal found 6/8![Frontier logo]()
$327
This Delta deal was found by Cheapflights users on 6/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 7/35:12 am
FSD
- RDU
1 stop4h 21m
Delta
Wed 7/87:10 pm
RDU
- FSD
1 stop4h 56m
Delta
Deal found 6/11![Delta logo]()
$315
This American Airlines deal was found by Cheapflights users on 6/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 7/36:00 am
FSD
- RDU
2 stops8h 25m
American Airlines
Wed 7/83:07 pm
RDU
- FSD
2 stops10h 11m
American Airlines
Deal found 6/11![American Airlines logo]()
$325
This American Airlines deal was found by Cheapflights users on 6/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 7/144:54 pm
FSD
- RDU
1 stop6h 05m
American Airlines
Wed 7/222:20 pm
RDU
- FSD
1 stop8h 38m
American Airlines
Deal found 6/12![American Airlines logo]()
$311
This Delta deal was found by Cheapflights users on 6/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 7/215:20 am
FSD
- RDU
1 stop6h 22m
Delta
Thu 7/306:59 pm
RDU
- FSD
1 stop5h 07m
Delta
Deal found 6/12![Delta logo]()
$359
One-way flights from Sioux Falls to DurhamSearch for one-way flight options from Sioux Falls to Durham. Find affordable one-way fares based on user searches. Data last updated June 13, 2026.
Search for one-way flight options from Sioux Falls to Durham. Find affordable one-way fares based on user searches. Data last updated June 13, 2026.
This Kiwi.com deal was found by Cheapflights users on 6/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 6/301:14 pm
FSD
- RDU
1 stop18h 46m
Multiple Airlines
Deal found 6/9![Multiple Airlines logo]()
$134
This Kiwi.com deal was found by Cheapflights users on 6/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 7/26:36 pm
FSD
- RDU
1 stop19h 31m
Multiple Airlines
Deal found 6/9![Multiple Airlines logo]()
$136
This Expedia deal was found by Cheapflights users on 6/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Expedia is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 7/278:08 pm
FSD
- RDU
1 stop14h 23m
Frontier
Deal found 6/8![Frontier logo]()
$140
This Kiwi.com deal was found by Cheapflights users on 6/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 7/279:54 am
FSD
- RDU
3 stops35h 49m
Multiple Airlines
Deal found 6/8![Multiple Airlines logo]()
$201
This Kiwi.com deal was found by Cheapflights users on 6/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 7/11:06 pm
FSD
- RDU
1 stop18h 53m
Multiple Airlines
Deal found 6/9![Multiple Airlines logo]()
$205
This American Airlines deal was found by Cheapflights users on 6/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 7/126:00 am
FSD
- RDU
1 stop6h 27m
American Airlines
Deal found 6/8![American Airlines logo]()
$309
Find flight deals from Sioux Falls to Durham
Keep the following information in mind while searching for Sioux Falls to Durham flight deals. Data was last updated June 13, 2026.
Most accurate provider | FlightHub 3 stars |
|---|---|
Most trusted provider | FlightHub 3 stars |
Round-trip from | $311 (Delta) |
One-way from | $134 (Kiwi.com) |
Popular in | March |
Cheapest in | August |
Average price | $427 |
Cheapflights Fare Finder
Customize your flight search to find flights from Sioux Falls to Durham that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated June 13, 2026.
Use the filters below to find and compare flights from Sioux Falls to Durham that are best for you.
Fly from
Fly to
Route
Depart
Return
Cheapest round-trip
Quickest round-trip
Sioux FallsRaleigh
FSD - RDU
FSDRDU
Sioux Falls Joe Foss Field
Tue 10/6
5:15 am-10:37 am
1 stop4h 22m
Raleigh-Durham
Sat 10/10
6:00 am-10:05 am
1 stop5h 05m
$311
Sioux FallsRaleigh
FSD - RDU
FSDRDU
Sioux Falls Joe Foss Field
Tue 7/7
6:00 am-1:27 pm
1 stop6h 27m
Raleigh-Durham
Wed 7/15
3:07 pm-12:18 am
2 stops10h 11m
$320
Sioux FallsRaleigh
FSD - RDU
FSDRDU
Sioux Falls Joe Foss Field
Fri 7/3
4:43 pm-12:02 am
1 stop6h 19m
Raleigh-Durham
Wed 7/8
3:07 pm-12:18 am
2 stops10h 11m
$320
Sioux FallsRaleigh
FSD - RDU
FSDRDU
Sioux Falls Joe Foss Field
Sat 8/1
7:35 am-2:01 pm
1 stop5h 26m
Raleigh-Durham
Sat 8/8
5:12 pm-11:31 pm
1 stop7h 19m
$339
Sioux FallsRaleigh
FSD - RDU
FSDRDU
Sioux Falls Joe Foss Field
Sat 8/1
5:20 am-12:42 pm
1 stop6h 22m
Raleigh-Durham
Sat 8/8
6:58 pm-10:51 pm
1 stop4h 53m
$387
Sioux FallsRaleigh
FSD - RDU
FSDRDU
Sioux Falls Joe Foss Field
Sat 8/29
1:33 pm-9:19 pm
1 stop6h 46m
Raleigh-Durham
Tue 9/1
4:23 pm-11:44 pm
1 stop8h 21m
$401
Sioux FallsRaleigh
FSD - RDU
FSDRDU
Sioux Falls Joe Foss Field
Wed 8/26
7:47 am-2:07 pm
1 stop5h 20m
Raleigh-Durham
Sat 8/29
4:23 pm-11:44 pm
1 stop8h 21m
$401
Cheapest one-way
Sioux FallsRaleigh
FSD - RDU
FSDRDU
Sioux Falls Joe Foss Field
Tue 6/30
1:14 pm-9:00 am
1 stop18h 46m
$134
Sioux FallsRaleigh
FSD - RDU
FSDRDU
Sioux Falls Joe Foss Field
Thu 7/2
6:36 pm-3:07 pm
1 stop19h 31m
$136
Sioux FallsRaleigh
FSD - RDU
FSDRDU
Sioux Falls Joe Foss Field
Mon 7/27
8:08 pm-11:31 am
1 stop14h 23m
$140
Showing 1-10 of 13 resultsSorted by cheapest first
Best time to book a flight from Sioux Falls to Durham
Have a flexible travel schedule? Discover the best time to fly to Durham from Sioux Falls with our price prediction graph.
FSD-RDU
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.
Cheapflights Insights
Everything you need to know about your flight from Sioux Falls to Durham
FSD-DU8
FSD-RDU
How much does it cost to fly round-trip from Sioux Falls to Durham?
Reviews of airlines servicing Durham
Get insights into the airlines that provide service to Durham. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Durham. Reviews last updated June 13, 2026.
See what other customers who have flown with Delta,United Airlines, andAmerican Airlines from Sioux Falls to Durham have to say. You can also see how each airline compares in terms of entertainment options, comfort, food, crew/service, and boarding process.
Overall
7.9
Comfort
7.8
Entertainment
7.8
Food
7.2
Crew
8.5
Boarding
8.1
Reviews
1 / 20
10.0
ExcellentAnonymous,May 2026
SEA - KOA
Overall
7.9
Comfort
7.8
Entertainment
7.8
Food
7.2
Crew
8.5
Boarding
8.1
Reviews
1 / 20
10.0
ExcellentAnonymous,May 2026
SEA - KOA
Overall
7.9
Comfort
7.8
Entertainment
7.8
Food
7.2
Crew
8.5
Boarding
8.1
Reviews
1 / 20
10.0
ExcellentAnonymous,May 2026
SEA - KOA
Overall
7.9
Comfort
7.8
Entertainment
7.8
Food
7.2
Crew
8.5
Boarding
8.1
Reviews
1 / 20
10.0
ExcellentAnonymous,May 2026
SEA - KOA
Related info for your journey
Find useful and relevant information for your journey from Sioux Falls to Durham. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.
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Sioux Falls and Durham flights
Browse other Sioux Falls and Durham flight options. Last updated on June 13, 2026.
Other flights from Sioux Falls
Browse through other flights departing from Sioux Falls. Flights are based on user searches made on Cheapflights and were last updated on June 13, 2026.
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Sioux Falls to Durham flights
Consider these flights traveling from Sioux Falls to Durham.
Top 3 airlines flying from Sioux Falls to Durham
Discover the top 3 airlines that operate flights from Sioux Falls to Durham. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated June 13, 2026.
| Airline | Cheapest | Average | Flexibility | On-time |
|---|---|---|---|---|
| Cheapest$258 | Average$340 | FlexibilityNo cancel fee | On-time71% | |
| Cheapest$258 | Average$358 | FlexibilityNo cancel fee | On-timeN/A | |
| Cheapest$307 | Average$473 | FlexibilityNo cancel fee | On-time69% |