$74+ Cheap flights from Chicago (CHI) to Durham, NC
This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 6/2. Fares are subject to change and may not be available on all flights or dates of travel.
CHI — RDU
May 26 — Jun 21
Round-trip
1 adult, Economy
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Find cheap flights from Chicago to Durham with Cheapflights
1. Tell us where you want to go
Enter your travel information like dates, passengers, trip type (one-way or round trip), and preferred cabin class then click “Find deals”2. Select your favorite providers
We find the providers serving your travel needs. Choose up to four travel providers to compare side-by-side for flights, hotels, or car rentals.3. Compare prices and book
Review each provider’s pricing and select the best option for you! Book through your favorite provider’s website for a seamless experience.Cheapflights Tip: The best prices from Chicago to Durham are usually found in October or September, booked 63 days in advance, depart on a Thursday or Friday and return on a Thursday
Cheap flight deals from Chicago to Durham
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Best
Last-minute
One-way
Cheapest flights from Chicago to DurhamExplore the most affordable flight options available from Chicago to Durham. Find the lowest fares from popular airlines and budget airlines, with prices last updated on April 26, 2026.
Explore the most affordable flight options available from Chicago to Durham. Find the lowest fares from popular airlines and budget airlines, with prices last updated on April 26, 2026.
This Kiwi.com deal was found by Cheapflights users on 4/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 5/1312:04 pm
MDW
- RDU
1 stop11h 29m
Frontier
Fri 5/156:15 am
RDU
- MDW
1 stop5h 54m
Frontier
Deal found 4/22![Frontier logo]()
$167
This Kiwi.com deal was found by Cheapflights users on 4/24. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 5/306:55 am
ORD
- RDU
1 stop16h 31m
Frontier
Tue 6/212:54 pm
RDU
- ORD
1 stop7h 57m
Frontier
Deal found 4/24![Frontier logo]()
$168
This Kiwi.com deal was found by Cheapflights users on 4/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 8/2412:04 pm
MDW
- RDU
1 stop11h 16m
Frontier
Sat 8/2911:47 am
RDU
- MDW
1 stop11h 24m
Frontier
Deal found 4/22![Frontier logo]()
$169
This Kiwi.com deal was found by Cheapflights users on 4/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 5/256:55 am
ORD
- RDU
1 stop16h 29m
Frontier
Wed 5/2712:33 pm
RDU
- ORD
1 stop20h 22m
Frontier
Deal found 4/22![Frontier logo]()
$170
This CheapOair deal was found by Cheapflights users on 4/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure CheapOair is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 5/231:50 pm
ORD
- RDU
1 stop9h 36m
Frontier
Thu 6/49:46 am
RDU
- ORD
1 stop27h 51m
Frontier
Deal found 4/25![Frontier logo]()
$171
This Frontier deal was found by Cheapflights users on 4/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Frontier is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 5/148:39 am
ORD
- RDU
Nonstop2h 19m
Frontier
Fri 5/152:32 pm
RDU
- ORD
1 stop9h 41m
Frontier
Deal found 4/21![Frontier logo]()
$172
This Kiwi.com deal was found by Cheapflights users on 4/24. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 6/69:20 am
ORD
- RDU
1 stop12h 26m
Frontier
Tue 6/99:40 am
RDU
- ORD
1 stop27h 45m
Frontier
Deal found 4/24![Frontier logo]()
$173
This Kiwi.com deal was found by Cheapflights users on 4/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 8/2211:59 am
MDW
- RDU
1 stop11h 23m
Frontier
Tue 8/256:15 am
RDU
- MDW
1 stop5h 57m
Frontier
Deal found 4/23![Frontier logo]()
$175
This Kiwi.com deal was found by Cheapflights users on 4/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 5/191:59 pm
ORD
- RDU
1 stop9h 34m
Frontier
Tue 5/266:21 pm
RDU
- ORD
2 stops38h 34m
Frontier
Deal found 4/21![Frontier logo]()
$175
This Expedia deal was found by Cheapflights users on 4/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Expedia is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 5/178:39 am
ORD
- RDU
Nonstop2h 19m
Multiple Airlines
Thu 5/2111:47 am
RDU
- ORD
1 stop12h 28m
Multiple Airlines
Deal found 4/21![Multiple Airlines logo]()
$176
This Kiwi.com deal was found by Cheapflights users on 4/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 6/312:04 pm
MDW
- RDU
1 stop11h 29m
Multiple Airlines
Mon 6/87:53 pm
RDU
- MDW
2 stops40h 16m
Multiple Airlines
Deal found 4/21![Multiple Airlines logo]()
$177
This Expedia deal was found by Cheapflights users on 4/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Expedia is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 5/191:59 pm
ORD
- RDU
1 stop9h 34m
Multiple Airlines
Thu 5/2111:47 am
RDU
- ORD
1 stop12h 28m
Multiple Airlines
Deal found 4/25![Multiple Airlines logo]()
$177
Best flights from Chicago to DurhamDiscover carefully curated flight deals from Chicago to Durham that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated April 26, 2026.
Discover carefully curated flight deals from Chicago to Durham that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated April 26, 2026.
This United Airlines deal was found by Cheapflights users on 4/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 5/189:35 pm
ORD
- RDU
Nonstop2h 15m
United Airlines
Wed 6/38:00 am
RDU
- ORD
Nonstop2h 26m
United Airlines
Deal found 4/21![United Airlines logo]()
$226
This Southwest deal was found by Cheapflights users on 4/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 5/237:50 am
MDW
- RDU
Nonstop1h 50m
Southwest
Tue 5/266:40 pm
RDU
- MDW
Nonstop2h 00m
Southwest
Deal found 4/21![Southwest logo]()
$227
This Southwest deal was found by Cheapflights users on 4/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 5/307:50 am
MDW
- RDU
Nonstop1h 50m
Southwest
Wed 6/36:40 pm
RDU
- MDW
Nonstop2h 00m
Southwest
Deal found 4/25![Southwest logo]()
$251
This United Airlines deal was found by Cheapflights users on 4/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 5/257:30 am
ORD
- RDU
Nonstop2h 20m
United Airlines
Wed 5/2711:35 am
RDU
- ORD
Nonstop2h 30m
United Airlines
Deal found 4/25![United Airlines logo]()
$251
This Southwest deal was found by Cheapflights users on 4/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 8/2412:50 pm
MDW
- RDU
Nonstop1h 55m
Southwest
Sat 8/293:50 pm
RDU
- MDW
Nonstop2h 00m
Southwest
Deal found 4/22![Southwest logo]()
$261
This United Airlines deal was found by Cheapflights users on 4/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 5/236:12 pm
ORD
- RDU
1 stop4h 17m
United Airlines
Mon 5/258:00 am
RDU
- ORD
Nonstop2h 26m
United Airlines
Deal found 4/22![United Airlines logo]()
$261
This Southwest deal was found by Cheapflights users on 4/24. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 5/309:15 am
MDW
- RDU
1 stop5h 00m
Southwest
Tue 6/26:40 pm
RDU
- MDW
Nonstop2h 00m
Southwest
Deal found 4/24![Southwest logo]()
$261
This United Airlines deal was found by Cheapflights users on 4/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 5/266:25 pm
ORD
- RDU
Nonstop2h 12m
United Airlines
Wed 5/278:00 am
RDU
- ORD
Nonstop2h 26m
United Airlines
Deal found 4/23![United Airlines logo]()
$281
This Southwest deal was found by Cheapflights users on 4/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 5/116:55 pm
MDW
- RDU
Nonstop1h 50m
Southwest
Thu 5/146:25 am
RDU
- MDW
1 stop6h 35m
Southwest
Deal found 4/22![Southwest logo]()
$301
This United Airlines deal was found by Cheapflights users on 4/24. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 5/149:05 am
ORD
- RDU
Nonstop2h 11m
United Airlines
Sun 5/1710:05 am
RDU
- ORD
Nonstop2h 26m
United Airlines
Deal found 4/24![United Airlines logo]()
$307
This Southwest deal was found by Cheapflights users on 4/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 9/75:30 am
MDW
- RDU
1 stop8h 55m
Southwest
Thu 9/106:45 pm
RDU
- MDW
Nonstop1h 55m
Southwest
Deal found 4/23![Southwest logo]()
$309
This United Airlines deal was found by Cheapflights users on 4/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 5/242:13 pm
ORD
- RDU
Nonstop2h 14m
United Airlines
Tue 5/266:00 am
RDU
- ORD
1 stop4h 36m
United Airlines
Deal found 4/23![United Airlines logo]()
$309
This United Airlines deal was found by Cheapflights users on 4/24. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 6/47:26 am
ORD
- RDU
Nonstop2h 20m
United Airlines
Sun 6/76:15 am
RDU
- ORD
1 stop4h 21m
United Airlines
Deal found 4/24![United Airlines logo]()
$311
This Southwest deal was found by Cheapflights users on 4/24. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 5/146:55 pm
MDW
- RDU
Nonstop1h 50m
Southwest
Sun 5/172:05 pm
RDU
- MDW
Nonstop1h 55m
Southwest
Deal found 4/24![Southwest logo]()
$327
This United Airlines deal was found by Cheapflights users on 4/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 5/223:53 pm
ORD
- RDU
1 stop6h 36m
United Airlines
Tue 5/268:00 am
RDU
- ORD
Nonstop2h 26m
United Airlines
Deal found 4/23![United Airlines logo]()
$322
This Southwest deal was found by Cheapflights users on 4/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 6/167:40 am
MDW
- RDU
Nonstop1h 55m
Southwest
Thu 6/187:55 pm
RDU
- MDW
1 stop4h 05m
Southwest
Deal found 4/20![Southwest logo]()
$337
This Southwest deal was found by Cheapflights users on 4/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 8/66:30 pm
MDW
- RDU
Nonstop1h 55m
Southwest
Sun 8/911:55 am
RDU
- MDW
Nonstop1h 50m
Southwest
Deal found 4/23![Southwest logo]()
$337
This United Airlines deal was found by Cheapflights users on 4/24. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 5/296:25 pm
ORD
- RDU
Nonstop2h 12m
United Airlines
Wed 6/311:35 am
RDU
- ORD
Nonstop2h 30m
United Airlines
Deal found 4/24![United Airlines logo]()
$351
This Southwest deal was found by Cheapflights users on 4/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 6/116:55 pm
MDW
- RDU
Nonstop1h 50m
Southwest
Mon 6/157:35 pm
RDU
- MDW
Nonstop2h 00m
Southwest
Deal found 4/21![Southwest logo]()
$337
This United Airlines deal was found by Cheapflights users on 4/24. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 6/69:38 pm
ORD
- RDU
Nonstop2h 12m
United Airlines
Wed 6/106:00 am
RDU
- ORD
1 stop7h 06m
United Airlines
Deal found 4/24![United Airlines logo]()
$351
This United Airlines deal was found by Cheapflights users on 4/24. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 6/36:25 pm
ORD
- RDU
Nonstop2h 12m
United Airlines
Sun 6/710:05 am
RDU
- ORD
Nonstop2h 26m
United Airlines
Deal found 4/24![United Airlines logo]()
$367
This Southwest deal was found by Cheapflights users on 4/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 5/1311:55 am
ORD
- RDU
2 stops8h 40m
Southwest
Sun 5/176:05 am
RDU
- ORD
2 stops7h 45m
Southwest
Deal found 4/21![Southwest logo]()
$367
Last-minute flights from Chicago to DurhamDiscover last-minute flight deals from Chicago to Durham. Data last updated April 26, 2026 and is based on user searches.
Discover last-minute flight deals from Chicago to Durham. Data last updated April 26, 2026 and is based on user searches.
This Kiwi.com deal was found by Cheapflights users on 4/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 5/1312:04 pm
MDW
- RDU
1 stop11h 29m
Frontier
Fri 5/156:15 am
RDU
- MDW
1 stop5h 54m
Frontier
Deal found 4/22![Frontier logo]()
$167
This Frontier deal was found by Cheapflights users on 4/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Frontier is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 5/148:39 am
ORD
- RDU
Nonstop2h 19m
Frontier
Fri 5/152:32 pm
RDU
- ORD
1 stop9h 41m
Frontier
Deal found 4/21![Frontier logo]()
$172
This Expedia deal was found by Cheapflights users on 4/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Expedia is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 5/178:39 am
ORD
- RDU
Nonstop2h 19m
Multiple Airlines
Thu 5/2111:47 am
RDU
- ORD
1 stop12h 28m
Multiple Airlines
Deal found 4/21![Multiple Airlines logo]()
$176
This Kiwi.com deal was found by Cheapflights users on 4/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 5/191:59 pm
ORD
- RDU
1 stop9h 34m
Frontier
Tue 5/266:21 pm
RDU
- ORD
2 stops38h 34m
Frontier
Deal found 4/21![Frontier logo]()
$175
This Expedia deal was found by Cheapflights users on 4/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Expedia is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 5/191:59 pm
ORD
- RDU
1 stop9h 34m
Multiple Airlines
Thu 5/2111:47 am
RDU
- ORD
1 stop12h 28m
Multiple Airlines
Deal found 4/25![Multiple Airlines logo]()
$177
This Kiwi.com deal was found by Cheapflights users on 4/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 5/207:15 am
ORD
- RDU
1 stop16h 18m
Multiple Airlines
Tue 5/266:21 pm
RDU
- ORD
2 stops14h 34m
Multiple Airlines
Deal found 4/22![Multiple Airlines logo]()
$178
This CheapOair deal was found by Cheapflights users on 4/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure CheapOair is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 5/231:50 pm
ORD
- RDU
1 stop9h 36m
Frontier
Thu 6/49:46 am
RDU
- ORD
1 stop27h 51m
Frontier
Deal found 4/25![Frontier logo]()
$171
This Kiwi.com deal was found by Cheapflights users on 4/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 5/256:55 am
ORD
- RDU
1 stop16h 29m
Frontier
Wed 5/2712:33 pm
RDU
- ORD
1 stop20h 22m
Frontier
Deal found 4/22![Frontier logo]()
$170
This Kiwi.com deal was found by Cheapflights users on 4/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 5/266:00 am
MDW
- RDU
1 stop4h 59m
Frontier
Fri 5/296:15 am
RDU
- MDW
1 stop5h 54m
Frontier
Deal found 4/25![Frontier logo]()
$169
This Frontier deal was found by Cheapflights users on 4/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Frontier is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 5/286:00 am
MDW
- RDU
1 stop4h 59m
Frontier
Sun 5/316:15 am
RDU
- MDW
1 stop5h 57m
Frontier
Deal found 4/21![Frontier logo]()
$180
This Kiwi.com deal was found by Cheapflights users on 4/24. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 5/2912:04 pm
MDW
- RDU
1 stop11h 20m
Frontier
Wed 6/36:15 am
RDU
- MDW
1 stop5h 54m
Frontier
Deal found 4/24![Frontier logo]()
$178
This Kiwi.com deal was found by Cheapflights users on 4/24. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 5/306:55 am
ORD
- RDU
1 stop16h 31m
Frontier
Tue 6/212:54 pm
RDU
- ORD
1 stop7h 57m
Frontier
Deal found 4/24![Frontier logo]()
$168
One-way flights from Chicago to DurhamSearch for one-way flight options from Chicago to Durham. Find affordable one-way fares based on user searches. Data last updated April 26, 2026.
Search for one-way flight options from Chicago to Durham. Find affordable one-way fares based on user searches. Data last updated April 26, 2026.
This Kiwi.com deal was found by Cheapflights users on 4/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 6/26:00 am
MDW
- RDU
1 stop4h 59m
Frontier
Deal found 4/25![Frontier logo]()
$74
This Super.com deal was found by Cheapflights users on 4/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Super.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 5/154:52 pm
MDW
- RDU
1 stop25h 05m
Frontier
Deal found 4/21![Frontier logo]()
$75
This Super.com deal was found by Cheapflights users on 4/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Super.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 5/139:37 pm
ORD
- RDU
1 stop13h 51m
Frontier
Deal found 4/21![Frontier logo]()
$75
This Trip.com deal was found by Cheapflights users on 4/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Trip.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 5/1312:04 pm
MDW
- RDU
1 stop11h 29m
Frontier
Deal found 4/21![Frontier logo]()
$77
This Kiwi.com deal was found by Cheapflights users on 4/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 5/114:52 pm
MDW
- RDU
1 stop15h 29m
Frontier
Deal found 4/23![Frontier logo]()
$78
This Trip.com deal was found by Cheapflights users on 4/24. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Trip.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 6/246:00 am
MDW
- RDU
1 stop17h 21m
Frontier
Deal found 4/24![Frontier logo]()
$81
This Kiwi.com deal was found by Cheapflights users on 4/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 5/216:55 am
ORD
- RDU
1 stop16h 13m
Frontier
Deal found 4/25![Frontier logo]()
$81
This Kiwi.com deal was found by Cheapflights users on 4/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 6/206:00 am
MDW
- RDU
1 stop17h 22m
Frontier
Deal found 4/23![Frontier logo]()
$82
This Kiwi.com deal was found by Cheapflights users on 4/24. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 5/216:00 am
MDW
- RDU
1 stop4h 59m
Frontier
Deal found 4/24![Frontier logo]()
$83
This Kiwi.com deal was found by Cheapflights users on 4/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 5/239:37 pm
ORD
- RDU
1 stop12h 54m
Frontier
Deal found 4/23![Frontier logo]()
$83
This Kiwi.com deal was found by Cheapflights users on 4/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 5/206:00 am
MDW
- RDU
1 stop17h 33m
Frontier
Deal found 4/25![Frontier logo]()
$84
This Kiwi.com deal was found by Cheapflights users on 4/24. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 6/76:00 am
MDW
- RDU
1 stop17h 24m
Frontier
Deal found 4/24![Frontier logo]()
$85
Find flight deals from Chicago to Durham
Keep the following information in mind while searching for Chicago to Durham flight deals. Data was last updated April 26, 2026.
Most accurate provider | FlightHub 3 stars |
|---|---|
Most trusted provider | FlightHub 3 stars |
Round-trip from | $167 (Kiwi.com) |
One-way from | $74 (Kiwi.com) |
Popular in | January |
Cheapest in | October |
Average price | $297 |
Cheapflights Fare Finder
Customize your flight search to find flights from Chicago to Durham that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated April 26, 2026.
Use the filters below to find and compare flights from Chicago to Durham that are best for you.
Fly from
Fly to
Route
Depart
Return
Cheapest round-trip
ChicagoRaleigh
ORD - RDU
ORDRDU
Chicago O'Hare Intl
Mon 5/18
9:35 pm-12:50 am
Nonstop2h 15m
Raleigh-Durham
Wed 6/3
8:00 am-9:26 am
Nonstop2h 26m
$226
ChicagoRaleigh
MDW - RDU
MDWRDU
Chicago Midway
Sat 5/23
7:50 am-10:40 am
Nonstop1h 50m
Raleigh-Durham
Tue 5/26
6:40 pm-7:40 pm
Nonstop2h 00m
$227
ChicagoRaleigh
MDW - RDU
MDWRDU
Chicago Midway
Sat 5/30
7:50 am-10:40 am
Nonstop1h 50m
Raleigh-Durham
Wed 6/3
6:40 pm-7:40 pm
Nonstop2h 00m
$251
ChicagoRaleigh
ORD - RDU
ORDRDU
Chicago O'Hare Intl
Mon 5/25
7:30 am-10:50 am
Nonstop2h 20m
Raleigh-Durham
Wed 5/27
11:35 am-1:05 pm
Nonstop2h 30m
$251
ChicagoRaleigh
MDW - RDU
MDWRDU
Chicago Midway
Mon 8/24
12:50 pm-3:45 pm
Nonstop1h 55m
Raleigh-Durham
Sat 8/29
3:50 pm-4:50 pm
Nonstop2h 00m
$261
ChicagoRaleigh
ORD - RDU
ORDRDU
Chicago O'Hare Intl
Sat 5/23
6:12 pm-11:29 pm
1 stop4h 17m
Raleigh-Durham
Mon 5/25
8:00 am-9:26 am
Nonstop2h 26m
$261
ChicagoRaleigh
MDW - RDU
MDWRDU
Chicago Midway
Sat 5/30
9:15 am-3:15 pm
1 stop5h 00m
Raleigh-Durham
Tue 6/2
6:40 pm-7:40 pm
Nonstop2h 00m
$261
ChicagoRaleigh
ORD - RDU
ORDRDU
Chicago O'Hare Intl
Tue 5/26
6:25 pm-9:37 pm
Nonstop2h 12m
Raleigh-Durham
Wed 5/27
8:00 am-9:26 am
Nonstop2h 26m
$281
ChicagoRaleigh
MDW - RDU
MDWRDU
Chicago Midway
Mon 5/11
6:55 pm-9:45 pm
Nonstop1h 50m
Raleigh-Durham
Thu 5/14
6:25 am-12:00 pm
1 stop6h 35m
$301
ChicagoRaleigh
ORD - RDU
ORDRDU
Chicago O'Hare Intl
Thu 5/14
9:05 am-12:16 pm
Nonstop2h 11m
Raleigh-Durham
Sun 5/17
10:05 am-11:31 am
Nonstop2h 26m
$307
Showing 1-10 of 43 resultsSorted by cheapest first
Best time to book a flight from Chicago to Durham
Have a flexible travel schedule? Discover the best time to fly to Durham from Chicago with our price prediction graph.
MDW-RDU
ORD-RDU
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.
Cheapflights Insights
Everything you need to know about your flight from Chicago to Durham
CHI-DU8
MDW-RDU
ORD-RDU
What is the cheapest time of day to fly from CHI to DU8?
Find hourly flight availability from Chicago to Durham. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated April 26, 2026.
Unlike in the afternoon, when flights are generally more expensive, you can save up to 11% on flights from Chicago to Durham by exploring options for tickets at noon.
What is the cheapest day to fly from Chicago to Durham?
Use this chart to determine the cheapest time to fly round-trip from Chicago to Durham. Price data was last updated on April 25, 2026.
Travelers seeking maximum savings on their Chicago to Durham flight should consider departing on Friday at noon when fares are most often at their lowest. Monday afternoons flights should be avoided if possible as fares are typically the most expensive at this time.
Weekly flight availability from Chicago to Durham
Explore weekly flight availability from Chicago to Durham. Discover flights operating on different days of the week, giving you the flexibility to choose a travel day that best fits your plans. Compare info to find the most convenient option for your journey. Data last updated April 26, 2026.
The most flights from CHI to DU8 are scheduled on a Friday (38 on average). You will have fewer flight options on Thursday, which is when the least amount of flights are scheduled (17 on average).
How much does it cost to fly round-trip from Chicago to Durham?
Reviews of airlines servicing Durham
Get insights into the airlines that provide service to Durham. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Durham. Reviews last updated April 26, 2026.
Get a feel of what it's like to fly with Southwest,United Airlines, andAmerican Airlines from Chicago to Durham by reading reviews from past customers. Users have also rated airlines in terms of entertainment options, comfort, food, crew/service, and boarding process.
Comfort
8.0
Crew
8.6
Entertainment
7.5
Overall
8.0
Boarding
8.1
Food
7.0
Reviews
1 / 20
2.0
MediocreDominic,Mar 2026
MCO - SMF
Comfort
8.0
Crew
8.6
Entertainment
7.5
Overall
8.0
Boarding
8.1
Food
7.0
Reviews
1 / 20
2.0
MediocreDominic,Mar 2026
MCO - SMF
Comfort
8.0
Crew
8.6
Entertainment
7.5
Overall
8.0
Boarding
8.1
Food
7.0
Reviews
1 / 20
2.0
MediocreDominic,Mar 2026
MCO - SMF
Comfort
8.0
Crew
8.6
Entertainment
7.5
Overall
8.0
Boarding
8.1
Food
7.0
Reviews
1 / 20
2.0
MediocreDominic,Mar 2026
MCO - SMF
Comfort
8.0
Crew
8.6
Entertainment
7.5
Overall
8.0
Boarding
8.1
Food
7.0
Reviews
1 / 20
2.0
MediocreDominic,Mar 2026
MCO - SMF
Related info for your journey
Find useful and relevant information for your journey from Chicago to Durham. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.
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Toggle through the tabs below to find thousands of options on Cheapflights for your next trip.
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Alternative routes for Chicago to Durham
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Complete your trip
Complete your trip to Durham by adding a car rental and/or hotel reservation to your travel itinerary.
Search flights from Chicago to Durham by cabin class
Find flights from Chicago to Durham, based on your preferred cabin class, be it economy, premium economy, business, or first class.
Chicago and Durham flights
Browse other Chicago and Durham flight options. Last updated on April 26, 2026.
Other flights from Chicago
Browse through other flights departing from Chicago. Flights are based on user searches made on Cheapflights and were last updated on April 26, 2026.
Popular flight searches
Check out other popular destinations found by fellow travelers in 2026
Chicago to Durham flights
Consider these flights traveling from Chicago to Durham.
Top 6 airlines flying from Chicago to Durham
Discover the top 6 airlines that operate flights from Chicago to Durham. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated April 26, 2026.
| Airline | Cheapest | Average | Flexibility | On-time |
|---|---|---|---|---|
| Cheapest$66 | Average$198 | FlexibilityNo cancel fee | On-time62% | |
| Cheapest$159 | Average$307 | FlexibilityNo cancel fee | On-time69% | |
| Cheapest$166 | Average$180 | FlexibilityNo cancel fee | On-time62% | |
| Cheapest$168 | Average$298 | FlexibilityNo cancel fee | On-time63% | |
| Cheapest$175 | Average$378 | FlexibilityNo cancel fee | On-time71% | |
| Cheapest$223 | Average$324 | FlexibilityNo cancel fee | On-timeN/A |