$98+ Cheap flights from Chicago (CHI) to Durham, NC
This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 9/15. Fares are subject to change and may not be available on all flights or dates of travel.
CHI — RDU
Jul 23 — Jul 301
Round-trip
1 adult, Economy
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Find cheap flights from Chicago to Durham with Cheapflights
1. Tell us where you want to go
Enter your travel information like dates, passengers, trip type (one-way or round trip), and preferred cabin class then click “Find deals”2. Select your favorite providers
We find the providers serving your travel needs. Choose up to four travel providers to compare side-by-side for flights, hotels, or car rentals.3. Compare prices and book
Review each provider’s pricing and select the best option for you! Book through your favorite provider’s website for a seamless experience.Cheapflights Tip: The best prices from Chicago to Durham are usually found in October or September, booked 63 days in advance, depart on a Friday or Thursday and return on a Thursday
Cheap flight deals from Chicago to Durham
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Best
Last-minute
One-way
Cheapest flights from Chicago to DurhamExplore the most affordable flight options available from Chicago to Durham. Find the lowest fares from popular airlines and budget airlines, with prices last updated on June 23, 2026.
Explore the most affordable flight options available from Chicago to Durham. Find the lowest fares from popular airlines and budget airlines, with prices last updated on June 23, 2026.
This Kiwi.com deal was found by Cheapflights users on 6/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 8/208:05 am
ORD
- RDU
1 stop12h 10m
Frontier
Sun 8/233:47 pm
RDU
- ORD
1 stop22h 13m
Frontier
Deal found 6/20![Frontier logo]()
$238
This Frontier deal was found by Cheapflights users on 6/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Frontier is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 7/1812:11 pm
MDW
- RDU
1 stop10h 52m
Frontier
Tue 7/216:15 am
RDU
- MDW
1 stop5h 52m
Frontier
Deal found 6/21![Frontier logo]()
$240
This Kiwi.com deal was found by Cheapflights users on 6/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 8/208:05 am
ORD
- RDU
1 stop12h 10m
Frontier
Tue 8/2512:53 pm
RDU
- ORD
1 stop11h 15m
Frontier
Deal found 6/21![Frontier logo]()
$240
This Frontier deal was found by Cheapflights users on 6/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Frontier is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 8/2711:50 am
MDW
- RDU
1 stop11h 09m
Frontier
Mon 8/311:21 pm
RDU
- MDW
1 stop8h 10m
Frontier
Deal found 6/22![Frontier logo]()
$241
This Kiwi.com deal was found by Cheapflights users on 6/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 9/242:03 pm
ORD
- RDU
1 stop9h 14m
Frontier
Sat 10/104:05 pm
RDU
- ORD
1 stop5h 23m
Frontier
Deal found 6/22![Frontier logo]()
$241
This Kiwi.com deal was found by Cheapflights users on 6/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 9/22:06 pm
ORD
- RDU
1 stop17h 26m
Frontier
Sat 9/56:05 am
RDU
- ORD
1 stop15h 03m
Frontier
Deal found 6/22![Frontier logo]()
$242
This Kiwi.com deal was found by Cheapflights users on 6/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 7/221:50 pm
ORD
- RDU
1 stop17h 11m
Frontier
Wed 7/295:29 pm
RDU
- ORD
1 stop6h 41m
Frontier
Deal found 6/21![Frontier logo]()
$243
This Kiwi.com deal was found by Cheapflights users on 6/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 9/207:25 am
MDW
- RDU
1 stop23h 05m
Frontier
Sat 9/264:20 pm
RDU
- MDW
1 stop6h 38m
Frontier
Deal found 6/18![Frontier logo]()
$244
This Kiwi.com deal was found by Cheapflights users on 6/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 7/208:05 am
ORD
- RDU
2 stops26h 10m
Multiple Airlines
Mon 7/278:29 pm
RDU
- ORD
1 stop27h 41m
Multiple Airlines
Deal found 6/22![Multiple Airlines logo]()
$244
This Kiwi.com deal was found by Cheapflights users on 6/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 9/237:25 am
MDW
- RDU
1 stop6h 42m
Frontier
Sun 10/46:35 am
RDU
- MDW
1 stop5h 23m
Frontier
Deal found 6/22![Frontier logo]()
$245
This Kiwi.com deal was found by Cheapflights users on 6/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 7/151:50 pm
ORD
- RDU
1 stop9h 14m
Frontier
Mon 7/207:32 pm
RDU
- ORD
1 stop28h 38m
Frontier
Deal found 6/20![Frontier logo]()
$245
This Kiwi.com deal was found by Cheapflights users on 6/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 8/28:05 am
ORD
- RDU
1 stop8h 04m
Multiple Airlines
Fri 8/710:59 am
RDU
- ORD
2 stops26h 16m
Multiple Airlines
Deal found 6/21![Multiple Airlines logo]()
$246
Best flights from Chicago to DurhamDiscover carefully curated flight deals from Chicago to Durham that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated June 23, 2026.
Discover carefully curated flight deals from Chicago to Durham that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated June 23, 2026.
This Southwest deal was found by Cheapflights users on 6/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 8/87:40 am
MDW
- RDU
Nonstop1h 55m
Southwest
Mon 8/106:45 pm
RDU
- MDW
Nonstop1h 55m
Southwest
Deal found 6/22![Southwest logo]()
$253
This United Airlines deal was found by Cheapflights users on 6/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 8/189:10 am
ORD
- RDU
Nonstop2h 23m
United Airlines
Thu 8/206:55 am
RDU
- ORD
1 stop6h 04m
United Airlines
Deal found 6/21![United Airlines logo]()
$259
This Delta deal was found by Cheapflights users on 6/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 8/16:00 am
MDW
- RDU
1 stop5h 42m
Delta
Thu 8/65:32 am
RDU
- MDW
1 stop4h 45m
Delta
Deal found 6/19![Delta logo]()
$273
This Southwest deal was found by Cheapflights users on 6/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 8/136:30 pm
MDW
- RDU
Nonstop1h 55m
Southwest
Sat 8/153:50 pm
RDU
- MDW
Nonstop2h 00m
Southwest
Deal found 6/17![Southwest logo]()
$269
This United Airlines deal was found by Cheapflights users on 6/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 8/2012:50 pm
ORD
- RDU
Nonstop2h 12m
United Airlines
Thu 8/276:55 am
RDU
- ORD
1 stop6h 04m
United Airlines
Deal found 6/19![United Airlines logo]()
$275
This Southwest deal was found by Cheapflights users on 6/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 8/512:45 pm
MDW
- RDU
2 stops5h 05m
Southwest
Tue 8/111:45 pm
RDU
- MDW
2 stops6h 20m
Southwest
Deal found 6/18![Southwest logo]()
$279
This Delta deal was found by Cheapflights users on 6/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 9/199:29 am
MDW
- RDU
1 stop5h 52m
Delta
Sun 9/275:34 am
RDU
- MDW
1 stop4h 33m
Delta
Deal found 6/20![Delta logo]()
$307
This Southwest deal was found by Cheapflights users on 6/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 9/18:35 am
MDW
- RDU
Nonstop2h 00m
Southwest
Fri 9/46:45 pm
RDU
- MDW
Nonstop1h 55m
Southwest
Deal found 6/22![Southwest logo]()
$287
This United Airlines deal was found by Cheapflights users on 6/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 9/112:50 pm
ORD
- RDU
Nonstop2h 11m
United Airlines
Wed 9/25:09 pm
RDU
- ORD
Nonstop2h 30m
United Airlines
Deal found 6/22![United Airlines logo]()
$317
This Southwest deal was found by Cheapflights users on 6/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 7/305:10 pm
MDW
- RDU
1 stop5h 45m
Southwest
Sat 8/83:50 pm
RDU
- MDW
Nonstop2h 00m
Southwest
Deal found 6/21![Southwest logo]()
$297
This United Airlines deal was found by Cheapflights users on 6/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 6/308:40 am
ORD
- RDU
1 stop4h 28m
United Airlines
Wed 7/110:59 am
RDU
- ORD
Nonstop2h 30m
United Airlines
Deal found 6/19![United Airlines logo]()
$332
This Southwest deal was found by Cheapflights users on 6/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 8/78:50 am
MDW
- RDU
Nonstop2h 00m
Southwest
Mon 8/106:45 pm
RDU
- MDW
Nonstop1h 55m
Southwest
Deal found 6/22![Southwest logo]()
$303
This United Airlines deal was found by Cheapflights users on 6/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 7/236:55 am
ORD
- RDU
Nonstop2h 13m
United Airlines
Mon 7/2710:00 am
RDU
- ORD
Nonstop2h 26m
United Airlines
Deal found 6/19![United Airlines logo]()
$337
This United Airlines deal was found by Cheapflights users on 6/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 7/183:53 pm
ORD
- RDU
1 stop6h 36m
United Airlines
Sun 7/1910:00 am
RDU
- ORD
Nonstop2h 26m
United Airlines
Deal found 6/20![United Airlines logo]()
$340
This Southwest deal was found by Cheapflights users on 6/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 8/35:20 pm
MDW
- RDU
1 stop4h 05m
Southwest
Sat 8/87:30 am
RDU
- MDW
Nonstop1h 50m
Southwest
Deal found 6/18![Southwest logo]()
$313
This United Airlines deal was found by Cheapflights users on 6/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 8/16:55 am
ORD
- RDU
Nonstop2h 13m
United Airlines
Thu 8/610:32 am
RDU
- ORD
1 stop7h 20m
United Airlines
Deal found 6/19![United Airlines logo]()
$343
This Southwest deal was found by Cheapflights users on 6/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 7/87:40 am
MDW
- RDU
Nonstop1h 55m
Southwest
Sun 7/127:15 am
RDU
- MDW
Nonstop1h 55m
Southwest
Deal found 6/17![Southwest logo]()
$330
This United Airlines deal was found by Cheapflights users on 6/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 8/82:13 pm
ORD
- RDU
Nonstop2h 14m
United Airlines
Mon 8/1010:32 am
RDU
- ORD
1 stop4h 57m
United Airlines
Deal found 6/22![United Airlines logo]()
$343
This United Airlines deal was found by Cheapflights users on 6/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 8/16:25 pm
ORD
- RDU
Nonstop2h 12m
United Airlines
Mon 8/36:00 am
RDU
- ORD
1 stop4h 36m
United Airlines
Deal found 6/18![United Airlines logo]()
$347
This United Airlines deal was found by Cheapflights users on 6/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 7/19:10 am
ORD
- RDU
Nonstop2h 23m
United Airlines
Sat 7/48:05 am
RDU
- ORD
Nonstop2h 26m
United Airlines
Deal found 6/18![United Airlines logo]()
$355
Last-minute flights from Chicago to DurhamDiscover last-minute flight deals from Chicago to Durham. Data last updated June 23, 2026 and is based on user searches.
Discover last-minute flight deals from Chicago to Durham. Data last updated June 23, 2026 and is based on user searches.
This Kiwi.com deal was found by Cheapflights users on 6/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 7/81:50 pm
ORD
- RDU
1 stop17h 11m
Frontier
Mon 7/1312:04 pm
RDU
- ORD
1 stop8h 49m
Frontier
Deal found 6/18![Frontier logo]()
$238
This Kiwi.com deal was found by Cheapflights users on 6/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 7/81:50 pm
ORD
- RDU
1 stop17h 11m
Multiple Airlines
Mon 7/138:29 pm
RDU
- ORD
1 stop27h 41m
Multiple Airlines
Deal found 6/19![Multiple Airlines logo]()
$241
This Kiwi.com deal was found by Cheapflights users on 6/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 7/148:05 am
ORD
- RDU
1 stop8h 04m
Frontier
Sun 7/196:14 pm
RDU
- ORD
1 stop14h 39m
Frontier
Deal found 6/22![Frontier logo]()
$251
This Kiwi.com deal was found by Cheapflights users on 6/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 7/151:50 pm
ORD
- RDU
1 stop9h 14m
Frontier
Mon 7/207:32 pm
RDU
- ORD
1 stop28h 38m
Frontier
Deal found 6/20![Frontier logo]()
$245
This Kiwi.com deal was found by Cheapflights users on 6/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 7/168:05 am
ORD
- RDU
1 stop8h 04m
Frontier
Tue 7/216:14 pm
RDU
- ORD
1 stop14h 39m
Frontier
Deal found 6/22![Frontier logo]()
$250
This Frontier deal was found by Cheapflights users on 6/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Frontier is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 7/1812:11 pm
MDW
- RDU
1 stop10h 52m
Frontier
Tue 7/216:15 am
RDU
- MDW
1 stop5h 52m
Frontier
Deal found 6/21![Frontier logo]()
$240
This Kiwi.com deal was found by Cheapflights users on 6/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 7/208:05 am
ORD
- RDU
2 stops26h 10m
Multiple Airlines
Mon 7/278:29 pm
RDU
- ORD
1 stop27h 41m
Multiple Airlines
Deal found 6/22![Multiple Airlines logo]()
$244
This Southwest deal was found by Cheapflights users on 6/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 7/217:40 am
MDW
- RDU
Nonstop1h 55m
Southwest
Wed 7/228:20 pm
RDU
- MDW
1 stop3h 55m
Southwest
Deal found 6/21![Southwest logo]()
$247
This American Airlines deal was found by Cheapflights users on 6/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 7/219:00 am
ORD
- RDU
1 stop5h 25m
American Airlines
Sat 7/253:57 pm
RDU
- ORD
Nonstop2h 44m
American Airlines
Deal found 6/21![American Airlines logo]()
$247
This Kiwi.com deal was found by Cheapflights users on 6/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 7/221:50 pm
ORD
- RDU
1 stop17h 11m
Frontier
Wed 7/295:29 pm
RDU
- ORD
1 stop6h 41m
Frontier
Deal found 6/21![Frontier logo]()
$243
This Frontier deal was found by Cheapflights users on 6/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Frontier is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 7/2312:11 pm
MDW
- RDU
1 stop10h 53m
Frontier
Wed 8/1211:56 am
RDU
- MDW
1 stop11h 07m
Frontier
Deal found 6/21![Frontier logo]()
$249
This Kiwi.com deal was found by Cheapflights users on 6/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 7/251:50 pm
ORD
- RDU
1 stop17h 21m
Frontier
Fri 7/317:32 pm
RDU
- ORD
1 stop28h 38m
Frontier
Deal found 6/20![Frontier logo]()
$248
One-way flights from Chicago to DurhamSearch for one-way flight options from Chicago to Durham. Find affordable one-way fares based on user searches. Data last updated June 23, 2026.
Search for one-way flight options from Chicago to Durham. Find affordable one-way fares based on user searches. Data last updated June 23, 2026.
This Trip.com deal was found by Cheapflights users on 6/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Trip.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 9/157:25 am
MDW
- RDU
1 stop6h 42m
Frontier
Deal found 6/18![Frontier logo]()
$98
This Trip.com deal was found by Cheapflights users on 6/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Trip.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 9/156:30 am
ORD
- RDU
1 stop7h 37m
Frontier
Deal found 6/18![Frontier logo]()
$98
This Kiwi.com deal was found by Cheapflights users on 6/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 9/142:03 pm
ORD
- RDU
1 stop9h 14m
Frontier
Deal found 6/18![Frontier logo]()
$103
This Kiwi.com deal was found by Cheapflights users on 6/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 9/1412:03 pm
MDW
- RDU
1 stop26h 04m
Frontier
Deal found 6/18![Frontier logo]()
$104
This Kiwi.com deal was found by Cheapflights users on 6/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 9/177:45 am
ORD
- RDU
1 stop29h 25m
Frontier
Deal found 6/18![Frontier logo]()
$116
This Southwest deal was found by Cheapflights users on 6/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 7/217:40 am
MDW
- RDU
Nonstop1h 55m
Southwest
Deal found 6/21![Southwest logo]()
$119
This American Airlines deal was found by Cheapflights users on 6/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 7/298:56 pm
ORD
- RDU
Nonstop2h 03m
American Airlines
Deal found 6/21![American Airlines logo]()
$119
This Frontier deal was found by Cheapflights users on 6/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Frontier is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 9/127:25 am
MDW
- RDU
1 stop6h 42m
Frontier
Deal found 6/21![Frontier logo]()
$120
This Kiwi.com deal was found by Cheapflights users on 6/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 7/16:55 am
ORD
- RDU
1 stop28h 04m
Frontier
Deal found 6/18![Frontier logo]()
$120
This Kiwi.com deal was found by Cheapflights users on 6/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 9/1912:03 pm
MDW
- RDU
1 stop18h 27m
Frontier
Deal found 6/20![Frontier logo]()
$121
This Kiwi.com deal was found by Cheapflights users on 6/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 7/31:29 pm
ORD
- RDU
1 stop17h 34m
Frontier
Deal found 6/21![Frontier logo]()
$121
This Kiwi.com deal was found by Cheapflights users on 6/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 7/112:04 pm
MDW
- RDU
1 stop22h 55m
Frontier
Deal found 6/19![Frontier logo]()
$122
Find flight deals from Chicago to Durham
Keep the following information in mind while searching for Chicago to Durham flight deals. Data was last updated June 23, 2026.
Most accurate provider | FlightHub 3 stars |
|---|---|
Most trusted provider | FlightHub 3 stars |
Round-trip from | $237 (Southwest) |
One-way from | $98 (Trip.com) |
Popular in | January |
Cheapest in | October |
Average price | $326 |
Cheapflights Fare Finder
Customize your flight search to find flights from Chicago to Durham that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated June 23, 2026.
Use the filters below to find and compare flights from Chicago to Durham that are best for you.
Fly from
Fly to
Route
Depart
Return
Cheapest round-trip
Quickest round-trip
ChicagoRaleigh
MDW - RDU
MDWRDU
Chicago Midway
Sat 8/8
7:40 am-10:35 am
Nonstop1h 55m
Raleigh-Durham
Mon 8/10
6:45 pm-7:40 pm
Nonstop1h 55m
$253
ChicagoRaleigh
ORD - RDU
ORDRDU
Chicago O'Hare Intl
Tue 8/18
9:10 am-12:33 pm
Nonstop2h 23m
Raleigh-Durham
Thu 8/20
6:55 am-11:59 am
1 stop6h 04m
$259
ChicagoRaleigh
MDW - RDU
MDWRDU
Chicago Midway
Thu 8/13
6:30 pm-9:25 pm
Nonstop1h 55m
Raleigh-Durham
Sat 8/15
3:50 pm-4:50 pm
Nonstop2h 00m
$269
ChicagoRaleigh
MDW - RDU
MDWRDU
Chicago Midway
Sat 8/1
6:00 am-12:42 pm
1 stop5h 42m
Raleigh-Durham
Thu 8/6
5:32 am-9:17 am
1 stop4h 45m
$273
ChicagoRaleigh
ORD - RDU
ORDRDU
Chicago O'Hare Intl
Thu 8/20
12:50 pm-4:02 pm
Nonstop2h 12m
Raleigh-Durham
Thu 8/27
6:55 am-11:59 am
1 stop6h 04m
$275
ChicagoRaleigh
MDW - RDU
MDWRDU
Chicago Midway
Wed 8/5
12:45 pm-6:50 pm
2 stops5h 05m
Raleigh-Durham
Tue 8/11
1:45 pm-7:05 pm
2 stops6h 20m
$279
ChicagoRaleigh
MDW - RDU
MDWRDU
Chicago Midway
Tue 9/1
8:35 am-11:35 am
Nonstop2h 00m
Raleigh-Durham
Fri 9/4
6:45 pm-7:40 pm
Nonstop1h 55m
$287
ChicagoRaleigh
MDW - RDU
MDWRDU
Chicago Midway
Thu 7/30
5:10 pm-11:55 pm
1 stop5h 45m
Raleigh-Durham
Sat 8/8
3:50 pm-4:50 pm
Nonstop2h 00m
$297
ChicagoRaleigh
MDW - RDU
MDWRDU
Chicago Midway
Fri 8/7
8:50 am-11:50 am
Nonstop2h 00m
Raleigh-Durham
Mon 8/10
6:45 pm-7:40 pm
Nonstop1h 55m
$303
ChicagoRaleigh
MDW - RDU
MDWRDU
Chicago Midway
Sat 9/19
9:29 am-4:21 pm
1 stop5h 52m
Raleigh-Durham
Sun 9/27
5:34 am-9:07 am
1 stop4h 33m
$307
Showing 1-10 of 42 resultsSorted by cheapest first
Best time to book a flight from Chicago to Durham
Have a flexible travel schedule? Discover the best time to fly to Durham from Chicago with our price prediction graph.
MDW-RDU
ORD-RDU
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.
Cheapflights Insights
Everything you need to know about your flight from Chicago to Durham
CHI-DU8
MDW-RDU
ORD-RDU
What is the cheapest time of day to fly from CHI to DU8?
Find hourly flight availability from Chicago to Durham. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated June 23, 2026.
Unlike in the afternoon, when flights are generally more expensive, you can save up to 13% on flights from Chicago to Durham by exploring options for tickets at noon.
Weekly flight availability from Chicago to Durham
Explore weekly flight availability from Chicago to Durham. Discover flights operating on different days of the week, giving you the flexibility to choose a travel day that best fits your plans. Compare info to find the most convenient option for your journey. Data last updated June 23, 2026.
The most flights from CHI to DU8 are scheduled on a Friday (36 on average). You will have fewer flight options on Thursday, which is when the least amount of flights are scheduled (28 on average).
How much does it cost to fly round-trip from Chicago to Durham?
What is the cheapest day to fly from Chicago to Durham?
Use this chart to determine the cheapest time to fly round-trip from Chicago to Durham. Price data was last updated on June 20, 2026.
Travelers seeking maximum savings on their Chicago to Durham flight should consider departing on Friday at noon when fares are most often at their lowest. Monday evenings flights should be avoided if possible as fares are typically the most expensive at this time.
Reviews of airlines servicing Durham
Get insights into the airlines that provide service to Durham. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Durham. Reviews last updated June 23, 2026.
Get a feel of what it's like to fly with Southwest,United Airlines, andAmerican Airlines from Chicago to Durham by reading reviews from past customers. Users have also rated airlines in terms of entertainment options, comfort, food, crew/service, and boarding process.
Overall
7.9
Boarding
8.1
Entertainment
7.5
Crew
8.6
Comfort
8.0
Food
7.0
Reviews
1 / 20
6.0
GoodReza,Jun 2026
TPA - MDW
Overall
7.9
Boarding
8.1
Entertainment
7.5
Crew
8.6
Comfort
8.0
Food
7.0
Reviews
1 / 20
6.0
GoodReza,Jun 2026
TPA - MDW
Overall
7.9
Boarding
8.1
Entertainment
7.5
Crew
8.6
Comfort
8.0
Food
7.0
Reviews
1 / 20
6.0
GoodReza,Jun 2026
TPA - MDW
Overall
7.9
Boarding
8.1
Entertainment
7.5
Crew
8.6
Comfort
8.0
Food
7.0
Reviews
1 / 20
6.0
GoodReza,Jun 2026
TPA - MDW
Overall
7.9
Boarding
8.1
Entertainment
7.5
Crew
8.6
Comfort
8.0
Food
7.0
Reviews
1 / 20
6.0
GoodReza,Jun 2026
TPA - MDW
Related info for your journey
Find useful and relevant information for your journey from Chicago to Durham. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.
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Alternative routes for Chicago to Durham
See prices for flight routes from nearby airports that may be better suited for you.
Complete your trip
Complete your trip to Durham by adding a car rental and/or hotel reservation to your travel itinerary.
Search flights from Chicago to Durham by cabin class
Find flights from Chicago to Durham, based on your preferred cabin class, be it economy, premium economy, business, or first class.
Chicago and Durham flights
Browse other Chicago and Durham flight options. Last updated on June 23, 2026.
Other flights from Chicago
Browse through other flights departing from Chicago. Flights are based on user searches made on Cheapflights and were last updated on June 23, 2026.
Popular flight searches
Check out other popular destinations found by fellow travelers in 2026
Chicago to Durham flights
Consider these flights traveling from Chicago to Durham.
Top 5 airlines flying from Chicago to Durham
Discover the top 5 airlines that operate flights from Chicago to Durham. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated June 23, 2026.
| Airline | Cheapest | Average | Flexibility | On-time |
|---|---|---|---|---|
| Cheapest$71 | Average$221 | FlexibilityNo cancel fee | On-time62% | |
| Cheapest$166 | Average$180 | FlexibilityNo cancel fee | On-time62% | |
| Cheapest$169 | Average$313 | FlexibilityNo cancel fee | On-time69% | |
| Cheapest$171 | Average$307 | FlexibilityNo cancel fee | On-time63% | |
| Cheapest$177 | Average$428 | FlexibilityNo cancel fee | On-time71% |