$84+ Cheap flights from Chicago (CHI) to Durham, NC
This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 4/26. Fares are subject to change and may not be available on all flights or dates of travel.
CHI — RDU
Mar 14 — Mar 211
1 adult, Economy
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Find cheap flights from Chicago to Durham with Cheapflights
1. Tell us where you want to go
Enter your travel information like dates, passengers, trip type (one-way or round trip), and preferred cabin class then click “Find deals”2. Select your favorite providers
We find the providers serving your travel needs. Choose up to four travel providers to compare side-by-side for flights, hotels, or car rentals.3. Compare prices and book
Review each provider’s pricing and select the best option for you! Book through your favorite provider’s website for a seamless experience.Cheapflights Tip: The best prices from Chicago to Durham are usually found in October or July, booked 75 days in advance, depart on a Thursday or Friday and return on a Thursday
Cheap flight deals from Chicago to Durham
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Best
Last-minute
One-way
Cheapest flights from Chicago to DurhamExplore the most affordable flight options available from Chicago to Durham. Find the lowest fares from popular airlines and budget airlines, with prices last updated on February 12, 2026.
Explore the most affordable flight options available from Chicago to Durham. Find the lowest fares from popular airlines and budget airlines, with prices last updated on February 12, 2026.
This Kiwi.com deal was found by Cheapflights users on 2/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 2/239:22 pm
MDW
- RDU
1 stop15h 36m
Frontier
Mon 3/25:10 pm
RDU
- MDW
1 stop6h 19m
Frontier
Deal found 2/11![Frontier logo]()
$164
This Frontier deal was found by Cheapflights users on 2/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Frontier is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 2/276:19 pm
ORD
- RDU
Nonstop2h 03m
Frontier
Sat 2/286:10 am
RDU
- ORD
1 stop5h 41m
Frontier
Deal found 2/9![Frontier logo]()
$164
This Kiwi.com deal was found by Cheapflights users on 2/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 2/278:16 pm
ORD
- RDU
2 stops26h 54m
Multiple Airlines
Fri 3/64:07 pm
RDU
- ORD
1 stop7h 32m
Multiple Airlines
Deal found 2/9![Multiple Airlines logo]()
$165
This Kiwi.com deal was found by Cheapflights users on 2/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 2/199:05 am
MDW
- RDU
1 stop7h 50m
Frontier
Sat 2/216:10 am
RDU
- MDW
1 stop16h 23m
Frontier
Deal found 2/9![Frontier logo]()
$166
This Expedia deal was found by Cheapflights users on 2/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Expedia is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 2/195:15 am
ORD
- RDU
1 stop7h 58m
Multiple Airlines
Mon 2/234:04 pm
RDU
- ORD
1 stop8h 11m
Multiple Airlines
Deal found 2/9![Multiple Airlines logo]()
$166
This Kiwi.com deal was found by Cheapflights users on 2/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 2/187:00 am
MDW
- RDU
1 stop11h 35m
Frontier
Fri 2/204:02 pm
RDU
- MDW
2 stops30h 31m
Frontier
Deal found 2/10![Frontier logo]()
$167
This Kiwi.com deal was found by Cheapflights users on 2/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 2/195:15 am
ORD
- RDU
1 stop7h 58m
Multiple Airlines
Thu 2/266:10 am
RDU
- ORD
1 stop5h 41m
Multiple Airlines
Deal found 2/10![Multiple Airlines logo]()
$167
This Kiwi.com deal was found by Cheapflights users on 2/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 2/2412:44 pm
ORD
- RDU
1 stop6h 46m
Multiple Airlines
Wed 2/256:25 am
RDU
- ORD
2 stops15h 48m
Multiple Airlines
Deal found 2/11![Multiple Airlines logo]()
$168
This Kiwi.com deal was found by Cheapflights users on 2/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 2/187:00 am
MDW
- RDU
1 stop11h 35m
Frontier
Sat 2/216:10 am
RDU
- MDW
1 stop16h 23m
Frontier
Deal found 2/10![Frontier logo]()
$169
This Kiwi.com deal was found by Cheapflights users on 2/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 2/276:19 pm
ORD
- RDU
Nonstop2h 03m
Multiple Airlines
Sat 3/76:08 pm
RDU
- ORD
1 stop7h 32m
Multiple Airlines
Deal found 2/11![Multiple Airlines logo]()
$169
This Kiwi.com deal was found by Cheapflights users on 2/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 3/76:00 am
MDW
- RDU
1 stop16h 16m
Frontier
Wed 3/114:12 pm
RDU
- MDW
1 stop7h 07m
Frontier
Deal found 2/9![Frontier logo]()
$170
This Kiwi.com deal was found by Cheapflights users on 2/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 3/135:01 am
ORD
- RDU
1 stop18h 10m
Frontier
Sun 3/156:00 am
RDU
- ORD
1 stop5h 52m
Frontier
Deal found 2/9![Frontier logo]()
$170
Best flights from Chicago to DurhamDiscover carefully curated flight deals from Chicago to Durham that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated February 12, 2026.
Discover carefully curated flight deals from Chicago to Durham that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated February 12, 2026.
This Kiwi.com deal was found by Cheapflights users on 2/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 2/276:19 pm
ORD
- RDU
Nonstop2h 03m
Multiple Airlines
Sat 3/76:08 pm
RDU
- ORD
1 stop7h 32m
Multiple Airlines
Deal found 2/11![Multiple Airlines logo]()
$169
This Southwest deal was found by Cheapflights users on 2/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 5/116:55 pm
MDW
- RDU
Nonstop1h 50m
Southwest
Wed 5/136:40 pm
RDU
- MDW
Nonstop2h 00m
Southwest
Deal found 2/9![Southwest logo]()
$177
This Delta deal was found by Cheapflights users on 2/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 5/196:30 am
MDW
- RDU
1 stop6h 06m
Delta
Sat 5/235:45 am
RDU
- MDW
1 stop3h 58m
Delta
Deal found 2/8![Delta logo]()
$187
This United Airlines deal was found by Cheapflights users on 2/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 5/149:15 pm
ORD
- RDU
Nonstop2h 15m
United Airlines
Tue 5/198:18 am
RDU
- ORD
Nonstop2h 32m
United Airlines
Deal found 2/9![United Airlines logo]()
$188
This Southwest deal was found by Cheapflights users on 2/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 5/156:55 pm
MDW
- RDU
Nonstop1h 50m
Southwest
Tue 5/196:40 pm
RDU
- MDW
Nonstop2h 00m
Southwest
Deal found 2/9![Southwest logo]()
$177
This Delta deal was found by Cheapflights users on 2/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 5/195:59 pm
ORD
- RDU
1 stop5h 09m
Delta
Sat 5/236:30 pm
RDU
- ORD
1 stop4h 19m
Delta
Deal found 2/8![Delta logo]()
$187
This United Airlines deal was found by Cheapflights users on 2/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 5/1311:00 am
ORD
- RDU
Nonstop2h 09m
United Airlines
Sun 5/176:20 am
RDU
- ORD
Nonstop2h 28m
United Airlines
Deal found 2/11![United Airlines logo]()
$188
This Kiwi.com deal was found by Cheapflights users on 2/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 4/86:01 pm
ORD
- RDU
2 stops13h 45m
Multiple Airlines
Mon 4/136:00 am
RDU
- ORD
1 stop5h 50m
Multiple Airlines
Deal found 2/11![Multiple Airlines logo]()
$191
This Southwest deal was found by Cheapflights users on 2/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 4/287:40 am
MDW
- RDU
Nonstop1h 50m
Southwest
Mon 5/47:45 pm
RDU
- MDW
Nonstop2h 00m
Southwest
Deal found 2/11![Southwest logo]()
$177
This United Airlines deal was found by Cheapflights users on 2/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 5/117:05 am
ORD
- RDU
Nonstop2h 07m
United Airlines
Wed 5/1310:05 am
RDU
- ORD
Nonstop2h 26m
United Airlines
Deal found 2/10![United Airlines logo]()
$188
This Kiwi.com deal was found by Cheapflights users on 2/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 3/56:51 pm
ORD
- RDU
1 stop21h 20m
Multiple Airlines
Sun 3/89:42 pm
RDU
- ORD
2 stops14h 14m
Multiple Airlines
Deal found 2/11![Multiple Airlines logo]()
$199
This Delta deal was found by Cheapflights users on 2/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 4/246:38 pm
MDW
- RDU
1 stop4h 01m
Delta
Sun 4/265:38 am
RDU
- MDW
1 stop4h 09m
Delta
Deal found 2/11![Delta logo]()
$207
This Delta deal was found by Cheapflights users on 2/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 4/227:14 am
ORD
- RDU
1 stop5h 07m
Delta
Sun 4/265:18 am
RDU
- ORD
1 stop4h 19m
Delta
Deal found 2/10![Delta logo]()
$207
This Southwest deal was found by Cheapflights users on 2/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 3/101:00 pm
MDW
- RDU
1 stop7h 45m
Southwest
Tue 3/176:30 pm
RDU
- MDW
Nonstop2h 05m
Southwest
Deal found 2/10![Southwest logo]()
$209
This United Airlines deal was found by Cheapflights users on 2/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 4/288:45 am
ORD
- RDU
1 stop4h 21m
United Airlines
Wed 4/2910:07 am
RDU
- ORD
Nonstop2h 25m
United Airlines
Deal found 2/8![United Airlines logo]()
$209
This Delta deal was found by Cheapflights users on 2/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 4/245:10 am
ORD
- RDU
1 stop4h 17m
Delta
Sun 4/265:38 am
RDU
- ORD
1 stop5h 31m
Delta
Deal found 2/11![Delta logo]()
$207
This United Airlines deal was found by Cheapflights users on 2/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 3/1010:40 am
ORD
- RDU
Nonstop2h 02m
United Airlines
Tue 3/176:13 am
RDU
- ORD
1 stop4h 37m
United Airlines
Deal found 2/10![United Airlines logo]()
$209
This Southwest deal was found by Cheapflights users on 2/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 4/242:40 pm
MDW
- RDU
Nonstop1h 50m
Southwest
Mon 4/277:45 pm
RDU
- MDW
Nonstop2h 00m
Southwest
Deal found 2/10![Southwest logo]()
$217
This United Airlines deal was found by Cheapflights users on 2/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 6/2010:48 am
ORD
- RDU
Nonstop2h 13m
United Airlines
Sat 6/278:00 am
RDU
- ORD
Nonstop2h 26m
United Airlines
Deal found 2/8![United Airlines logo]()
$217
This Southwest deal was found by Cheapflights users on 2/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 3/146:45 pm
MDW
- RDU
Nonstop1h 50m
Southwest
Tue 3/176:30 pm
RDU
- MDW
Nonstop2h 05m
Southwest
Deal found 2/9![Southwest logo]()
$218
Last-minute flights from Chicago to DurhamDiscover last-minute flight deals from Chicago to Durham. Data last updated February 12, 2026 and is based on user searches.
Discover last-minute flight deals from Chicago to Durham. Data last updated February 12, 2026 and is based on user searches.
This Kiwi.com deal was found by Cheapflights users on 2/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 2/187:00 am
MDW
- RDU
1 stop11h 35m
Frontier
Fri 2/204:02 pm
RDU
- MDW
2 stops30h 31m
Frontier
Deal found 2/10![Frontier logo]()
$167
This Kiwi.com deal was found by Cheapflights users on 2/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 2/187:00 am
MDW
- RDU
1 stop11h 35m
Frontier
Sat 2/216:10 am
RDU
- MDW
1 stop16h 23m
Frontier
Deal found 2/10![Frontier logo]()
$169
This Kiwi.com deal was found by Cheapflights users on 2/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 2/199:05 am
MDW
- RDU
1 stop7h 50m
Frontier
Sat 2/216:10 am
RDU
- MDW
1 stop16h 23m
Frontier
Deal found 2/9![Frontier logo]()
$166
This Expedia deal was found by Cheapflights users on 2/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Expedia is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 2/195:15 am
ORD
- RDU
1 stop7h 58m
Multiple Airlines
Mon 2/234:04 pm
RDU
- ORD
1 stop8h 11m
Multiple Airlines
Deal found 2/9![Multiple Airlines logo]()
$166
This Kiwi.com deal was found by Cheapflights users on 2/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 2/195:15 am
ORD
- RDU
1 stop7h 58m
Multiple Airlines
Thu 2/266:10 am
RDU
- ORD
1 stop5h 41m
Multiple Airlines
Deal found 2/10![Multiple Airlines logo]()
$167
This Kiwi.com deal was found by Cheapflights users on 2/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 2/239:22 pm
MDW
- RDU
1 stop15h 36m
Frontier
Mon 3/25:10 pm
RDU
- MDW
1 stop6h 19m
Frontier
Deal found 2/11![Frontier logo]()
$164
This Kiwi.com deal was found by Cheapflights users on 2/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 2/2412:44 pm
ORD
- RDU
1 stop6h 46m
Multiple Airlines
Wed 2/256:25 am
RDU
- ORD
2 stops15h 48m
Multiple Airlines
Deal found 2/11![Multiple Airlines logo]()
$168
This Frontier deal was found by Cheapflights users on 2/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Frontier is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 2/276:19 pm
ORD
- RDU
Nonstop2h 03m
Frontier
Sat 2/286:10 am
RDU
- ORD
1 stop5h 41m
Frontier
Deal found 2/9![Frontier logo]()
$164
This Kiwi.com deal was found by Cheapflights users on 2/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 2/278:16 pm
ORD
- RDU
2 stops26h 54m
Multiple Airlines
Fri 3/64:07 pm
RDU
- ORD
1 stop7h 32m
Multiple Airlines
Deal found 2/9![Multiple Airlines logo]()
$165
This Kiwi.com deal was found by Cheapflights users on 2/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 2/276:19 pm
ORD
- RDU
Nonstop2h 03m
Multiple Airlines
Sat 3/76:08 pm
RDU
- ORD
1 stop7h 32m
Multiple Airlines
Deal found 2/11![Multiple Airlines logo]()
$169
This Kiwi.com deal was found by Cheapflights users on 2/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 3/76:00 am
MDW
- RDU
1 stop16h 16m
Frontier
Wed 3/114:12 pm
RDU
- MDW
1 stop7h 07m
Frontier
Deal found 2/9![Frontier logo]()
$170
This Kiwi.com deal was found by Cheapflights users on 2/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 3/135:01 am
ORD
- RDU
1 stop18h 10m
Frontier
Sun 3/156:00 am
RDU
- ORD
1 stop5h 52m
Frontier
Deal found 2/9![Frontier logo]()
$170
One-way flights from Chicago to DurhamSearch for one-way flight options from Chicago to Durham. Find affordable one-way fares based on user searches. Data last updated February 12, 2026.
Search for one-way flight options from Chicago to Durham. Find affordable one-way fares based on user searches. Data last updated February 12, 2026.
This Kiwi.com deal was found by Cheapflights users on 2/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 4/269:14 am
MDW
- RDU
1 stop21h 42m
Frontier
Deal found 2/9![Frontier logo]()
$84
This Expedia deal was found by Cheapflights users on 2/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Expedia is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 5/171:12 pm
ORD
- RDU
Nonstop2h 07m
Frontier
Deal found 2/9![Frontier logo]()
$84
This Super.com deal was found by Cheapflights users on 2/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Super.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 5/179:14 am
MDW
- RDU
1 stop21h 42m
Frontier
Deal found 2/9![Frontier logo]()
$85
This Frontier deal was found by Cheapflights users on 2/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Frontier is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 3/26:19 pm
ORD
- RDU
Nonstop2h 03m
Frontier
Deal found 2/9![Frontier logo]()
$85
This Priceline deal was found by Cheapflights users on 2/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Priceline is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 5/136:00 am
MDW
- RDU
1 stop8h 04m
Frontier
Deal found 2/11![Frontier logo]()
$86
This Mytrip deal was found by Cheapflights users on 2/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Mytrip is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 3/178:05 am
ORD
- RDU
1 stop12h 48m
Frontier
Deal found 2/9![Frontier logo]()
$86
This Trip.com deal was found by Cheapflights users on 2/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Trip.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 3/17:30 am
MDW
- RDU
1 stop26h 08m
Frontier
Deal found 2/9![Frontier logo]()
$87
This Trip.com deal was found by Cheapflights users on 2/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Trip.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 3/17:35 am
ORD
- RDU
1 stop26h 03m
Frontier
Deal found 2/9![Frontier logo]()
$87
This Kiwi.com deal was found by Cheapflights users on 2/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 5/157:30 am
MDW
- RDU
2 stops32h 37m
Multiple Airlines
Deal found 2/11![Multiple Airlines logo]()
$88
This Trip.com deal was found by Cheapflights users on 2/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Trip.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 2/194:42 pm
ORD
- RDU
1 stop6h 28m
Frontier
Deal found 2/11![Frontier logo]()
$88
This Southwest deal was found by Cheapflights users on 2/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 5/126:05 pm
MDW
- RDU
Nonstop1h 50m
Southwest
Deal found 2/9![Southwest logo]()
$89
This American Airlines deal was found by Cheapflights users on 2/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 4/148:56 pm
ORD
- RDU
Nonstop2h 03m
American Airlines
Deal found 2/9![American Airlines logo]()
$89
Find flight deals from Chicago to Durham
Keep the following information in mind while searching for Chicago to Durham flight deals. Data was last updated February 12, 2026.
Most accurate provider | FlightHub 3 stars |
|---|---|
Most trusted provider | FlightHub 3 stars |
Round-trip from | $164 (Kiwi.com) |
One-way from | $84 (Kiwi.com) |
Popular in | January |
Cheapest in | October |
Average price | $382 |
Cheapflights Fare Finder
Customize your flight search to find flights from Chicago to Durham that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated February 12, 2026.
Use the filters below to find and compare flights from Chicago to Durham that are best for you.
Fly from
Chicago
Fly to
Durham
Route
Depart
Return
Price
ChicagoRaleigh
ORD - RDU
ORDRDU
Chicago O'Hare Intl
Fri 2/27
6:19 pm-9:22 pm
Nonstop2h 03m
Raleigh-Durham
Sat 3/7
6:08 pm-12:40 am
1 stop7h 32m
$169
ChicagoRaleigh
MDW - RDU
MDWRDU
Chicago Midway
Mon 5/11
6:55 pm-9:45 pm
Nonstop1h 50m
Raleigh-Durham
Wed 5/13
6:40 pm-7:40 pm
Nonstop2h 00m
$177
ChicagoRaleigh
MDW - RDU
MDWRDU
Chicago Midway
Fri 5/15
6:55 pm-9:45 pm
Nonstop1h 50m
Raleigh-Durham
Tue 5/19
6:40 pm-7:40 pm
Nonstop2h 00m
$177
ChicagoRaleigh
MDW - RDU
MDWRDU
Chicago Midway
Tue 4/28
7:40 am-10:30 am
Nonstop1h 50m
Raleigh-Durham
Mon 5/4
7:45 pm-8:45 pm
Nonstop2h 00m
$177
ChicagoRaleigh
MDW - RDU
MDWRDU
Chicago Midway
Tue 5/19
6:30 am-1:36 pm
1 stop6h 06m
Raleigh-Durham
Sat 5/23
5:45 am-8:43 am
1 stop3h 58m
$187
ChicagoRaleigh
ORD - RDU
ORDRDU
Chicago O'Hare Intl
Tue 5/19
5:59 pm-12:08 am
1 stop5h 09m
Raleigh-Durham
Sat 5/23
6:30 pm-9:49 pm
1 stop4h 19m
$187
ChicagoRaleigh
ORD - RDU
ORDRDU
Chicago O'Hare Intl
Thu 5/14
9:15 pm-12:30 am
Nonstop2h 15m
Raleigh-Durham
Tue 5/19
8:18 am-9:50 am
Nonstop2h 32m
$188
ChicagoRaleigh
ORD - RDU
ORDRDU
Chicago O'Hare Intl
Wed 5/13
11:00 am-2:09 pm
Nonstop2h 09m
Raleigh-Durham
Sun 5/17
6:20 am-7:48 am
Nonstop2h 28m
$188
ChicagoRaleigh
ORD - RDU
ORDRDU
Chicago O'Hare Intl
Mon 5/11
7:05 am-10:12 am
Nonstop2h 07m
Raleigh-Durham
Wed 5/13
10:05 am-11:31 am
Nonstop2h 26m
$188
ChicagoRaleigh
ORD - RDU
ORDRDU
Chicago O'Hare Intl
Wed 4/8
6:01 pm-8:46 am
2 stops13h 45m
Raleigh-Durham
Mon 4/13
6:00 am-10:50 am
1 stop5h 50m
$191
Showing 1-10 of 42 results
Best time to book a flight from Chicago to Durham
Have a flexible travel schedule? Discover the best time to fly to Durham from Chicago with our price prediction graph.
MDW-RDU
ORD-RDU
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.
Cheapflights Insights
Everything you need to know about your flight from Chicago to Durham
CHI-DU8
MDW-RDU
ORD-RDU
How far ahead should I book a flight from Chicago to Durham?
Use this chart to determine the optimal time to book a round-trip flight from Chicago to Durham. Price data was last updated on February 6, 2026.
Booking 75 days in advance of your planned departure date is, on average, the best time to get cheap flights from Chicago to Durham. The general trend is that the closer you book to the departure date, the more expensive your flight will be.
What is the cheapest month to book a flight from Chicago to Durham?
Currently, October is the cheapest month in which you can book a flight from Chicago to Durham (average of $74). Flying from Chicago to Durham in April is currently the most expensive (average of $205). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.
What is the cheapest time of day to fly from CHI to DU8?
Find hourly flight availability from Chicago to Durham. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated February 12, 2026.
Unlike in the evening, when flights are generally more expensive, you can save up to 17% on flights from Chicago to Durham by exploring options for tickets in the morning.
What is the cheapest day to fly from Chicago to Durham?
Use this chart to determine the cheapest time to fly round-trip from Chicago to Durham. Price data was last updated on February 7, 2026.
Travelers seeking maximum savings on their Chicago to Durham flight should consider departing on Tuesday afternoons when fares are most often at their lowest. Tuesday evenings flights should be avoided if possible as fares are typically the most expensive at this time.
How much does it cost to fly round-trip from Chicago to Durham?
Reviews of airlines servicing Durham
Get insights into the airlines that provide service to Durham. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Durham. Reviews last updated February 12, 2026.
Get a feel of what it's like to fly with Southwest, United Airlines, and American Airlines from Chicago to Durham by reading reviews from past customers. Users have also rated airlines in terms of entertainment options, comfort, food, crew/service, and boarding process.
Entertainment
7.5
Comfort
8.0
Food
7.0
Crew
8.6
Boarding
8.1
Overall
8.0
Reviews
1 / 20
2.0
MediocreThomas,Dec 2025
SEA - DEN
Entertainment
7.5
Comfort
8.0
Food
7.0
Crew
8.6
Boarding
8.1
Overall
8.0
Reviews
1 / 20
2.0
MediocreThomas,Dec 2025
SEA - DEN
Entertainment
7.5
Comfort
8.0
Food
7.0
Crew
8.6
Boarding
8.1
Overall
8.0
Reviews
1 / 20
2.0
MediocreThomas,Dec 2025
SEA - DEN
Entertainment
7.5
Comfort
8.0
Food
7.0
Crew
8.6
Boarding
8.1
Overall
8.0
Reviews
1 / 20
2.0
MediocreThomas,Dec 2025
SEA - DEN
Entertainment
7.5
Comfort
8.0
Food
7.0
Crew
8.6
Boarding
8.1
Overall
8.0
Reviews
1 / 20
2.0
MediocreThomas,Dec 2025
SEA - DEN
Related info for your journey
Find useful and relevant information for your journey from Chicago to Durham. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.
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Alternative routes for Chicago to Durham
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Complete your trip
Complete your trip to Durham by adding a car rental and/or hotel reservation to your travel itinerary.
Search flights from Chicago to Durham by cabin class
Find flights from Chicago to Durham, based on your preferred cabin class, be it economy, premium economy, business, or first class.
Chicago and Durham flights
Browse other Chicago and Durham flight options. Last updated on February 12, 2026.
Other flights from Chicago
Browse through other flights departing from Chicago. Flights are based on user searches made on Cheapflights and were last updated on February 12, 2026.
Popular flight searches
Check out other popular destinations found by fellow travelers in 2026
Chicago to Durham flights
Consider these flights traveling from Chicago to Durham.
Top 6 airlines flying from Chicago to Durham
Discover the top 6 airlines that operate flights from Chicago to Durham. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated February 12, 2026.
| Airline | Cheapest | Average | Flexibility | On-time |
|---|---|---|---|---|
| Cheapest$67 | Average$209 | FlexibilityNo cancel fee | On-time62% | |
| Cheapest$157 | Average$297 | FlexibilityNo cancel fee | On-time69% | |
| Cheapest$166 | Average$180 | FlexibilityNo cancel fee | On-time62% | |
| Cheapest$170 | Average$333 | FlexibilityNo cancel fee | On-time71% | |
| Cheapest$174 | Average$306 | FlexibilityNo cancel fee | On-time63% | |
| Cheapest$223 | Average$324 | FlexibilityNo cancel fee | On-timeN/A |