Regardless of the time of day you decide to fly, the ticket price will remain around the same. Book flights from Orlando Airport to DuBois, Pennsylvania as you normally would.
For a flight from Orlando to DuBois, you will be flying into Jefferson County. DuBois Jefferson County (DUJ) is just 8.2 mi from the center of the city. Jefferson County is the only DuBois airport and it handles 0 inbound flights from Orlando per day. 0 airlines have flights to DuBois Jefferson County from Orlando on a regular basis.