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$221+ Cheap flights from Panama to Detroit Metropolitan Wayne County Airport (DTW)

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 2/9. Fares are subject to change and may not be available on all flights or dates of travel.
PTY — DTW
Oct 23 — Oct 301
Thu 10/23
Thu 10/30
1 adult, Economy
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Cheap flight deals from Panama to Detroit

Keep the following information in mind while searching for Panama to Detroit flight deals. Data was last updated September 23, 2025.

Round-trip from

$871
(American Airlines)

One-way from

$221
(Avianca Connect)
From Panama to Detroit Metropolitan Wayne County
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One-way flight from Panama to Detroit Metropolitan Wayne County
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Find flight deals from Panama to Detroit

Cheapest flights from Panama to Detroit
Explore the most affordable flight options available from Panama to Detroit. Find the lowest fares from popular airlines and budget airlines, with prices last updated on September 23, 2025.

This Kiwi.com deal was found by Cheapflights users on 9/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 10/1512:03 pmPTY - DTW
1 stop10h 27mMultiple Airlines
Sun 10/196:43 amDTW - PTY
1 stop14h 36mMultiple Airlines
Deal found 9/21$488
This Kiwi.com deal was found by Cheapflights users on 9/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 10/1412:03 pmPTY - DTW
1 stop10h 27mMultiple Airlines
Sat 10/186:43 amDTW - PTY
1 stop14h 36mMultiple Airlines
Deal found 9/21$512
This Kiwi.com deal was found by Cheapflights users on 9/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 10/138:10 amPTY - DTW
1 stop10h 50mMultiple Airlines
Sun 10/196:17 amDTW - PTY
1 stop14h 12mMultiple Airlines
Deal found 9/21$567
This Kiwi.com deal was found by Cheapflights users on 9/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 10/138:10 amPTY - DTW
1 stop10h 50mMultiple Airlines
Fri 10/176:17 amDTW - PTY
1 stop11h 08mMultiple Airlines
Deal found 9/21$568
This Kiwi.com deal was found by Cheapflights users on 9/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 10/1312:03 pmPTY - DTW
1 stop10h 27mMultiple Airlines
Sat 10/186:43 amDTW - PTY
1 stop14h 36mMultiple Airlines
Deal found 9/21$591
This Kiwi.com deal was found by Cheapflights users on 9/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 10/149:25 amPTY - DTW
1 stop21h 51mMultiple Airlines
Fri 10/176:17 amDTW - PTY
2 stops27h 38mMultiple Airlines
Deal found 9/21$597
This Kiwi.com deal was found by Cheapflights users on 9/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 10/1512:03 pmPTY - DTW
1 stop10h 27mMultiple Airlines
Fri 10/176:17 amDTW - PTY
2 stops27h 38mMultiple Airlines
Deal found 9/21$600
This Kiwi.com deal was found by Cheapflights users on 9/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 10/147:55 amPTY - DTW
2 stops23h 50mMultiple Airlines
Sun 10/196:17 amDTW - PTY
1 stop14h 12mMultiple Airlines
Deal found 9/21$620

Cheapflights Fare Finder

 
Customize your flight search to find flights from Panama to Detroit that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated September 23, 2025.
Use the filters below to find and compare flights from Panama to Detroit Metropolitan Wayne County Airport that are best for you.

Fly from

Panama

Fly to

Detroit

Route

Depart

Return

Price

Panama CityDetroit

PTY - DTW

PTYDTW

Panama City Tocumen Intl

Wed 10/15

12:03 pm-11:30 pm

1 stop10h 27m

Detroit Metropolitan Wayne County

Sun 10/19

6:43 am-8:19 pm

1 stop14h 36m

$488

Panama CityDetroit

PTY - DTW

PTYDTW

Panama City Tocumen Intl

Mon 10/13

8:10 am-8:00 pm

1 stop10h 50m

Detroit Metropolitan Wayne County

Sun 10/19

6:17 am-7:29 pm

1 stop14h 12m

$567

Panama CityDetroit

PTY - DTW

PTYDTW

Panama City Tocumen Intl

Mon 10/13

8:10 am-8:00 pm

1 stop10h 50m

Detroit Metropolitan Wayne County

Fri 10/17

6:17 am-4:25 pm

1 stop11h 08m

$568

Panama CityDetroit

PTY - DTW

PTYDTW

Panama City Tocumen Intl

Mon 10/13

3:25 am-10:37 pm

2 stops18h 12m

Detroit Metropolitan Wayne County

Sat 10/18

6:17 am-9:10 pm

2 stops15h 53m

$584

Panama CityDetroit

PTY - DTW

PTYDTW

Panama City Tocumen Intl

Wed 10/15

12:03 pm-11:30 pm

1 stop10h 27m

Detroit Metropolitan Wayne County

Fri 10/17

6:17 am-8:55 am

2 stops27h 38m

$600

Panama CityDetroit

PTY - DTW

PTYDTW

Panama City Tocumen Intl

Tue 10/14

7:55 am-8:45 am

2 stops23h 50m

Detroit Metropolitan Wayne County

Sun 10/19

6:17 am-7:29 pm

1 stop14h 12m

$620

Panama CityDetroit

PTY - DTW

PTYDTW

Panama City Tocumen Intl

Wed 10/15

9:33 pm-8:00 pm

1 stop21h 27m

Detroit Metropolitan Wayne County

Sat 10/18

9:30 am-9:10 pm

2 stops12h 40m

$678

Panama CityDetroit

PTY - DTW

PTYDTW

Panama City Tocumen Intl

Mon 10/13

9:34 am-9:54 am

2 stops23h 20m

Detroit Metropolitan Wayne County

Sat 10/18

7:22 am-7:33 pm

1 stop13h 11m

$693

Panama CityDetroit

PTY - DTW

PTYDTW

Panama City Tocumen Intl

Mon 2/9

5:55 pm-2:09 pm

2 stops20h 14m

$221

Panama CityDetroit

PTY - DTW

PTYDTW

Panama City Tocumen Intl

Wed 10/29

5:55 pm-8:20 am

2 stops37h 25m

$253

Flights are sorted by cheapest round-trip flights first.

Deals found on 9/21

Showing 1-10 of 14 results
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Best time to book a flight from Panama to Detroit

Have a flexible travel schedule? Discover the best time to fly to Detroit from Panama with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Panama to Detroit Metropolitan Wayne County Airport

What is the cheapest time of day to fly from PA to DTW?

Find hourly flight availability from Panama to Detroit. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated September 23, 2025.

Regardless of the time of day you decide to fly, the ticket price will remain around the same. Book flights from Panama to Detroit Metropolitan Wayne County Airport as you normally would.

Related info for your journey

Find useful and relevant information for your journey from Panama to Detroit. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • What airport do you fly into for flights to Detroit from Panama?

    Detroit Metropolitan Wayne County (DTW), located 17.3 mi from the city center, is the airport you fly into when you book flights from Panama to Detroit.

  • Can I find deals for flights from Panama to Detroit that include hotel bookings?

    Yes. In addition to deals on Panama to Detroit flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Panama to Detroit?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Panama to Detroit.

  • Can I find deals for business class flights from Panama to Detroit?

    Yes. Cheapflights offers flight deals from Panama to Detroit by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Panama to Detroit Metropolitan Wayne County Airport?

    Currently, August is the cheapest month in which you can book a flight from Panama to Detroit Metropolitan Wayne County Airport (average of $250). Flying from Panama to Detroit Metropolitan Wayne County Airport in March is currently the most expensive (average of $305). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

Traveling to a place near Detroit Metropolitan Wayne County Airport?

Book flights to Detroit Metropolitan Wayne County Airport if you plan to visit one of these locations
Sterling Heights
Dearborn
Troy
Warren
Southfield
Novi
Clarkston
Allen Park
Utica
Plymouth
Monroe
Wixom
Brighton
Livonia
Roseville
Fremont
Port Huron
Auburn Hills
Madison Heights
Southgate

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