$290+ Cheap flights from Panama to Detroit Metropolitan Wayne County Airport (DTW)
This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 1/31. Fares are subject to change and may not be available on all flights or dates of travel.
Find cheap flights from Panama to Detroit with Cheapflights
1. Tell us where you want to go
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Review each provider’s pricing and select the best option for you! Book through your favorite provider’s website for a seamless experience.Find flight deals from Panama to Detroit
Cheapest flights from Panama to DetroitExplore the most affordable flight options available from Panama to Detroit. Find the lowest fares from popular airlines and budget airlines, with prices last updated on November 12, 2025.
Explore the most affordable flight options available from Panama to Detroit. Find the lowest fares from popular airlines and budget airlines, with prices last updated on November 12, 2025.
This Kiwi.com deal was found by Cheapflights users on 11/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
This Mytrip deal was found by Cheapflights users on 11/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Mytrip is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
This Mytrip deal was found by Cheapflights users on 11/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Mytrip is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Cheap flight deals from Panama to Detroit
Keep the following information in mind while searching for Panama to Detroit flight deals. Data was last updated November 12, 2025.
Round-trip from | $515 (Kiwi.com) |
|---|---|
One-way from | $290 (Kiwi.com) |
Cheapflights Fare Finder
Use the filters below to find and compare flights from Panama to Detroit Metropolitan Wayne County Airport that are best for you.
Fly from
Fly to
Route
Depart
Return
Price
Panama CityDetroit
PTY - DTW
PTYDTW
Panama City Tocumen Intl
Mon 5/4
10:55 pm-8:20 pm
2 stops20h 25m
Detroit Metropolitan Wayne County
Mon 9/28
11:06 am-6:37 pm
1 stop8h 31m
Panama CityDetroit
PTY - DTW
PTYDTW
Panama City Tocumen Intl
Sun 12/21
2:55 am-9:32 pm
2 stops18h 37m
Detroit Metropolitan Wayne County
Wed 12/31
5:23 pm-8:50 am
2 stops15h 27m
Panama CityDetroit
PTY - DTW
PTYDTW
Panama City Tocumen Intl
Wed 12/10
7:50 pm-3:40 pm
2 stops19h 50m
Detroit Metropolitan Wayne County
Wed 12/17
6:00 am-6:55 pm
3 stops36h 55m
Panama CityDetroit
PTY - DTW
PTYDTW
Panama City Tocumen Intl
Fri 4/24
2:20 pm-9:24 am
1 stop18h 04m
Detroit Metropolitan Wayne County
Tue 4/28
7:45 pm-12:55 pm
1 stop18h 10m
Panama CityDetroit
PTY - DTW
PTYDTW
Panama City Tocumen Intl
Sat 1/31
7:50 pm-10:12 pm
3 stops26h 22m
Panama CityDetroit
PTY - DTW
PTYDTW
Panama City Tocumen Intl
Mon 3/30
10:05 pm-7:51 pm
2 stops20h 46m
Panama CityDetroit
PTY - DTW
PTYDTW
Panama City Tocumen Intl
Sun 3/29
10:05 pm-7:51 pm
2 stops20h 46m
Panama CityDetroit
PTY - DTW
PTYDTW
Panama City Tocumen Intl
Thu 4/2
3:20 am-11:49 pm
2 stops19h 29m
Panama CityDetroit
PTY - DTW
PTYDTW
Panama City Tocumen Intl
Fri 4/3
1:50 pm-10:47 am
2 stops19h 57m
Panama CityDetroit
PTY - DTW
PTYDTW
Panama City Tocumen Intl
Sat 4/4
9:55 am-11:49 pm
2 stops12h 54m
Best time to book a flight from Panama to Detroit
Have a flexible travel schedule? Discover the best time to fly to Detroit from Panama with our price prediction graph.
Cheapflights Insights
Everything you need to know about your flight from Panama to Detroit Metropolitan Wayne County Airport
What is the cheapest time of day to fly from PA to DTW?
Find hourly flight availability from Panama to Detroit. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated November 12, 2025.
When flying from Panama to Detroit Metropolitan Wayne County Airport, the time of day you fly usually plays a role in the price. Save by searching for a flight in the afternoon, which can drop the price by up to 22% versus a flight in the morning.