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$225+ Cheap flights from Panama to Detroit Metropolitan Wayne County Airport (DTW)

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 3/23. Fares are subject to change and may not be available on all flights or dates of travel.
PTY — DTW
Feb 6 — Feb 131
Fri 2/6
Fri 2/13
1 adult, Economy
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Cheap flight deals from Panama to Detroit

Keep the following information in mind while searching for Panama to Detroit flight deals. Data was last updated January 7, 2026.

Round-trip from

$619
(Mytrip)

One-way from

$225
(Trip.com)
From Panama to Detroit Metropolitan Wayne County
Search Deals
One-way flight from Panama to Detroit Metropolitan Wayne County
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Find flight deals from Panama to Detroit

Cheapest flights from Panama to Detroit
Explore the most affordable flight options available from Panama to Detroit. Find the lowest fares from popular airlines and budget airlines, with prices last updated on January 7, 2026.

This Mytrip deal was found by Cheapflights users on 1/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Mytrip is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 2/216:34 pmPTY - DTW
2 stops21h 23mMultiple Airlines
Sat 2/2810:10 amDTW - PTY
1 stop10h 24mMultiple Airlines
Deal found 1/7$619
This Avianca Connect deal was found by Cheapflights users on 1/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Avianca Connect is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 1/159:45 amPTY - DTW
2 stops12h 27mMultiple Airlines
Sun 1/186:35 amDTW - PTY
2 stops18h 25mMultiple Airlines
Deal found 1/6$627
This FlightHub deal was found by Cheapflights users on 1/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure FlightHub is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 2/47:50 pmPTY - DTW
2 stops28h 06mMultiple Airlines
Wed 2/117:45 pmDTW - PTY
2 stops47h 10mMultiple Airlines
Deal found 1/7$711
This Delta deal was found by Cheapflights users on 1/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 6/172:20 pmPTY - DTW
1 stop16h 35mDelta
Sat 6/277:45 pmDTW - PTY
1 stop18h 20mDelta
Deal found 1/7$770
This United Airlines deal was found by Cheapflights users on 1/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 2/214:41 pmPTY - DTW
1 stop31h 18mUnited Airlines
Sat 2/284:40 pmDTW - PTY
1 stop24h 27mUnited Airlines
Deal found 1/7$794
This Copa Airlines deal was found by Cheapflights users on 1/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Copa Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 2/46:41 pmPTY - DTW
1 stop15h 27mCopa Airlines
Wed 2/1111:05 amDTW - PTY
1 stop9h 30mCopa Airlines
Deal found 1/7$798

Cheapflights Fare Finder

 
Customize your flight search to find flights from Panama to Detroit that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated January 7, 2026.
Use the filters below to find and compare flights from Panama to Detroit Metropolitan Wayne County Airport that are best for you.

Fly from

Panama

Fly to

Detroit

Route

Depart

Return

Price

Panama CityDetroit

PTY - DTW

PTYDTW

Panama City Tocumen Intl

Sat 2/21

4:41 pm-9:32 am

2 stops16h 51m

Detroit Metropolitan Wayne County

Sat 2/28

6:10 pm-5:07 pm

2 stops22h 57m

$794

Panama CityDetroit

PTY - DTW

PTYDTW

Panama City Tocumen Intl

Wed 2/4

6:41 pm-10:08 am

1 stop15h 27m

Detroit Metropolitan Wayne County

Wed 2/11

11:05 am-8:35 pm

1 stop9h 30m

$798

Panama CityDetroit

PTY - DTW

PTYDTW

Panama City Tocumen Intl

Wed 2/4

11:35 am-10:06 pm

1 stop10h 31m

Detroit Metropolitan Wayne County

Wed 2/11

2:19 pm-2:45 pm

2 stops24h 26m

$802

Panama CityDetroit

PTY - DTW

PTYDTW

Panama City Tocumen Intl

Wed 6/17

2:20 pm-9:24 am

1 stop18h 04m

Detroit Metropolitan Wayne County

Tue 6/23

6:30 am-1:05 pm

1 stop7h 35m

$810

Panama CityDetroit

PTY - DTW

PTYDTW

Panama City Tocumen Intl

Mon 6/15

11:05 am-7:13 pm

3 stops31h 08m

Detroit Metropolitan Wayne County

Mon 6/29

8:00 am-8:55 am

3 stops25h 55m

$814

Panama CityDetroit

PTY - DTW

PTYDTW

Panama City Tocumen Intl

Wed 6/17

2:20 pm-12:45 am

1 stop9h 25m

Detroit Metropolitan Wayne County

Tue 7/7

5:20 am-1:07 pm

1 stop8h 47m

$867

Panama CityDetroit

PTY - DTW

PTYDTW

Panama City Tocumen Intl

Tue 6/16

5:25 pm-7:13 pm

3 stops24h 48m

Detroit Metropolitan Wayne County

Thu 6/25

5:05 am-10:10 am

3 stops30h 05m

$874

Panama CityDetroit

PTY - DTW

PTYDTW

Panama City Tocumen Intl

Sat 6/13

2:20 pm-9:24 am

1 stop18h 04m

Detroit Metropolitan Wayne County

Tue 6/23

6:30 am-1:05 pm

1 stop7h 35m

$879

Panama CityDetroit

PTY - DTW

PTYDTW

Panama City Tocumen Intl

Wed 6/17

2:20 pm-12:45 am

1 stop9h 25m

Detroit Metropolitan Wayne County

Fri 6/26

5:20 am-1:05 pm

1 stop8h 45m

$893

Panama CityDetroit

PTY - DTW

PTYDTW

Panama City Tocumen Intl

Sat 6/13

2:20 pm-7:55 am

1 stop16h 35m

Detroit Metropolitan Wayne County

Thu 6/25

7:45 pm-1:05 pm

1 stop18h 20m

$906

Flights are sorted by cheapest round-trip flights first.

Deals found on 1/6

Showing 1-10 of 16 results
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Best time to book a flight from Panama to Detroit

Have a flexible travel schedule? Discover the best time to fly to Detroit from Panama with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Panama to Detroit Metropolitan Wayne County Airport
No data available for this route at this time. Please check back soon.

Related info for your journey

Find useful and relevant information for your journey from Panama to Detroit. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • What airport do you fly into for flights to Detroit from Panama?

    Detroit Metropolitan Wayne County (DTW), located 17.3 mi from the city center, is the airport you fly into when you book flights from Panama to Detroit.

  • How long is the flight from Panama to Detroit Metropolitan Wayne County Airport?

    A quick flight from Panama to Detroit Metropolitan Wayne County Airport can take about 15h 27m. United Airlines provides one of the quickest options available for as low as $798. The distance from Panama to Detroit Metropolitan Wayne County Airport is about 2302 mi. Both multi-stop and nonstop flights can be found to your destination and back.

  • Can I find deals for flights from Panama to Detroit that include hotel bookings?

    Yes. In addition to deals on Panama to Detroit flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Panama to Detroit?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Panama to Detroit.

  • Can I find deals for business class flights from Panama to Detroit?

    Yes. Cheapflights offers flight deals from Panama to Detroit by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

See more FAQs

Traveling to a place near Detroit Metropolitan Wayne County Airport?

Book flights to Detroit Metropolitan Wayne County Airport if you plan to visit one of these locations
Sterling Heights
Southfield
Dearborn
Troy
Warren
Auburn Hills
Clarkston
Allen Park
Utica
Novi
Rochester Hills
Roseville
Romulus
Monroe
Wixom
Ypsilanti
Brighton
Livonia
Plymouth
Fremont

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