$247+ Cheap flights from Florence, AL to Denver (MSL - DEN)
This is the cheapest round-trip flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 11/15. Fares are subject to change and may not be available on all flights or dates of travel.
MSL — DEN
Oct 22 — Oct 291
Round-trip
1 adult, Economy
We work with more than 300 partners to bring you better travel deals
Find cheap flights from Florence to Denver with Cheapflights
1. Tell us where you want to go
Enter your travel information like dates, passengers, trip type (one-way or round trip), and preferred cabin class then click “Find deals”2. Select your favorite providers
We find the providers serving your travel needs. Choose up to four travel providers to compare side-by-side for flights, hotels, or car rentals.3. Compare prices and book
Review each provider’s pricing and select the best option for you! Book through your favorite provider’s website for a seamless experience.Cheap flight deals from Florence to Denver
Cheapest
Best
Last-minute
One-way
Cheapest flights from Florence to DenverExplore the most affordable flight options available from Florence to Denver. Find the lowest fares from popular airlines and budget airlines, with prices last updated on September 22, 2026.
Explore the most affordable flight options available from Florence to Denver. Find the lowest fares from popular airlines and budget airlines, with prices last updated on September 22, 2026.
This Mytrip deal was found by Cheapflights users on 9/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Mytrip is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 10/37:25 am -
2 stops15h 24m
Sat 10/106:10 am -
3 stops28h 50m
Deal found 9/19![Multiple Airlines logo]()
$579
This Kiwi.com deal was found by Cheapflights users on 9/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 10/67:25 am -
2 stops25h 27m
Sat 10/1010:40 am -
1 stop24h 20m
Deal found 9/21![Multiple Airlines logo]()
$620
Best flights from Florence to DenverDiscover carefully curated flight deals from Florence to Denver that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated September 22, 2026.
Discover carefully curated flight deals from Florence to Denver that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated September 22, 2026.
This Mytrip deal was found by Cheapflights users on 9/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Mytrip is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 10/37:25 am -
2 stops15h 24m
Sat 10/106:10 am -
3 stops28h 50m
Deal found 9/19![Multiple Airlines logo]()
$579
This Kiwi.com deal was found by Cheapflights users on 9/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 10/67:25 am -
2 stops25h 27m
Sat 10/1010:40 am -
1 stop24h 20m
Deal found 9/21![Multiple Airlines logo]()
$620
Last-minute flights from Florence to DenverDiscover last-minute flight deals from Florence to Denver. Data last updated September 22, 2026 and is based on user searches.
Discover last-minute flight deals from Florence to Denver. Data last updated September 22, 2026 and is based on user searches.
This Mytrip deal was found by Cheapflights users on 9/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Mytrip is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 10/37:25 am -
2 stops15h 24m
Sat 10/106:10 am -
3 stops28h 50m
Deal found 9/19![Multiple Airlines logo]()
$579
This Kiwi.com deal was found by Cheapflights users on 9/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 10/67:25 am -
2 stops25h 27m
Sat 10/1010:40 am -
1 stop24h 20m
Deal found 9/21![Multiple Airlines logo]()
$620
One-way flights from Florence to DenverSearch for one-way flight options from Florence to Denver. Find affordable one-way fares based on user searches. Data last updated September 22, 2026.
Search for one-way flight options from Florence to Denver. Find affordable one-way fares based on user searches. Data last updated September 22, 2026.
This Kiwi.com deal was found by Cheapflights users on 9/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 11/157:25 am -
1 stop12h 29m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 9/17![Multiple Airlines logo]()
$247
Find flight deals from Florence to Denver
Discover tips and strategies to find the most affordable flight options for your journey from Florence (MSL) to Denver (DEN). Learn about various techniques such as flexible date searches, comparing prices across and setting up price alerts. Use these methods to find the cheapest flights available for your travel needs. Data last updated September 22, 2026.
Most accurate provider | FlightHub 3 stars |
|---|---|
Most trusted provider | FlightHub 3 stars |
Round-trip from | $579 (Mytrip) |
One-way from | $247 (Kiwi.com) |
Cheapflights Fare Finder
Customize your flight search to find flights from Florence to Denver that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 7,457,451 searches. Data last updated September 22, 2026.
Use the filters below to find and compare flights from Florence to Denver that are best for you.
Fly from
Fly to
Route
Depart
Return
Cheapest round-trip
Quickest round-trip
FlorenceDenver
MSL Florence Muscle Shoals - DEN Denver Intl
MSLDEN
Florence Muscle Shoals
Sun 11/15
7:25 am-6:54 pm
1 stop12h 29m
Denver Intl
Wed 12/31
12:00 am-1:00 am
Nonstop0h 00m
$247
FlorenceDenver
MSL Florence Muscle Shoals - DEN Denver Intl
MSLDEN
Florence Muscle Shoals
Sat 10/3
7:25 am-9:49 pm
2 stops15h 24m
Denver Intl
Sat 10/10
6:10 am-12:00 pm
3 stops28h 50m
$579
FlorenceDenver
MSL Florence Muscle Shoals - DEN Denver Intl
MSLDEN
Florence Muscle Shoals
Tue 10/6
7:25 am-7:52 am
2 stops25h 27m
Denver Intl
Sat 10/10
10:40 am-12:00 pm
1 stop24h 20m
$620
Sorted by cheapest first
- Most accurate provider: When it comes to deals on Florence, Alabama-Denver flights, users find the pricing of FlightHub to be most consistent on Cheapflights vs. FlightHub Users can find the same prices on Florence, Alabama-Denver flight deals on Cheapflights vs. FlightHub >95% of the time. Price accuracy is based on data collected from Florence, Alabama-Denver flight searches over the past month and is updated monthly.
- Most trusted provider: When it comes to deals on Florence, Alabama-Denver flights, Cheapflights users trust FlightHub the most. FlightHub has received a user feedback score of 3 out of 3 stars (3 being the best), meaning they have been trusted the most by Cheapflights users looking for Florence, Alabama-Denver flight deals. Provider user feedback score is based on Cheapflights searches over the past month and is updated monthly.
Best time to book a flight from Florence to Denver
Have a flexible travel schedule? Discover the best time to fly to Denver from Florence with our price prediction graph.
MSL-DEN
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.
Related info for your journey
Find useful and relevant information for your journey from Florence to Denver. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.
Traveling to a place near Denver?
Book flights to Denver if you plan to visit one of these locationsThornton
Westminster
Lakewood
Centennial
Black Hawk
Broomfield
Golden
Wheat Ridge
Silverthorne
Central City
Fort Morgan
Greeley
Cripple Creek
Frisco
Winter Park
Limon
Englewood
Manitou Springs
Glendale
Evergreen
Browse thousands of different options on Cheapflights for your next trip
Toggle through the tabs below to find thousands of options on Cheapflights for your next trip.
Alternative routes
Complete your trip
Denver flight routes
Flights by cabin class
Other flight options
Other flights from Florence
Popular flights