Cheap flights from Missouri to Columbus
STL — CMH
Nov 2 — Nov 91
Round-trip
1 adult, Economy
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1. Tell us where you want to go
Enter your travel information like dates, passengers, trip type (one-way or round trip), and preferred cabin class then click “Find deals”2. Select your favorite providers
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Review each provider’s pricing and select the best option for you! Book through your favorite provider’s website for a seamless experience.Find flight deals from Missouri to Columbus
Keep the following information in mind while searching for Missouri to Columbus flight deals. Data was last updated October 3, 2026.
Popular in | February |
|---|---|
Cheapest in | January |
Average price | $387 |
Cheapflights Insights
Everything you need to know about your flight from Missouri to Columbus
What is the cheapest month to book a flight from Missouri to Columbus?
Currently, January is the cheapest month in which you can book a flight from Missouri to Columbus (average of $332). Flying from Missouri to Columbus in March is currently the most expensive (average of $587). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.
What is the cheapest time of day to fly from MO to CMH?
Find hourly flight availability from Missouri to Columbus. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated October 3, 2026.
It’s typically best to fly out from Missouri to Columbus in the evening. Doing so could potentially save you 35% on the flight price compared to flying at noon, which is usually more expensive.
Related info for your journey
Find useful and relevant information for your journey from Missouri to Columbus. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.
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Alternative routes for Missouri to Columbus
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Complete your trip
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Search flights from Missouri to Columbus by cabin class
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Missouri and Columbus flights
Browse other Missouri and Columbus flight options. Last updated on October 3, 2026.
Popular flight searches
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Missouri to Columbus flights
Consider these flights traveling from Missouri to Columbus.
Top 4 airlines flying from Missouri to Columbus
Discover the top 4 airlines that operate flights from Missouri to Columbus. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 7,457,451 searches. Data last updated October 3, 2026.
| Airline | Cheapest | Average | Flexibility | On-time |
|---|---|---|---|---|
| Cheapest$230 | Average$413 | FlexibilityNo cancel fee | On-time63% | |
| Cheapest$248 | Average$278 | FlexibilityNo cancel fee | On-time71% | |
| Cheapest$248 | Average$421 | FlexibilityNo cancel fee | On-time69% | |
| Cheapest$283 | Average$478 | FlexibilityNo cancel fee | On-timeN/A |