$130+ Cheap flights from Biloxi, MS to Columbus
This is the cheapest round-trip flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 9/28. Fares are subject to change and may not be available on all flights or dates of travel.
MSY — CMH
Oct 9 — Oct 161
Round-trip
1 adult, Economy
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Cheapest flights from Biloxi to ColumbusExplore the most affordable flight options available from Biloxi to Columbus. Find the lowest fares from popular airlines and budget airlines, with prices last updated on September 9, 2026.
Explore the most affordable flight options available from Biloxi to Columbus. Find the lowest fares from popular airlines and budget airlines, with prices last updated on September 9, 2026.
This American Airlines deal was found by Cheapflights users on 9/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/25:42 pm -
1 stop5h 11m
Sun 10/46:00 am -
1 stop5h 40m
Deal found 9/7![American Airlines logo]()
$347
This Delta deal was found by Cheapflights users on 9/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/96:05 pm -
1 stop5h 39m
Sun 10/116:00 am -
1 stop4h 17m
Deal found 9/8![Delta logo]()
$367
This United Airlines deal was found by Cheapflights users on 9/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 9/194:59 pm -
1 stop5h 45m
Wed 9/236:30 am -
1 stop7h 54m
Deal found 9/4![United Airlines logo]()
$369
This United Airlines deal was found by Cheapflights users on 9/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/25:14 pm -
1 stop5h 30m
Sun 10/45:20 am -
2 stops9h 05m
Deal found 9/7![United Airlines logo]()
$389
This United Airlines deal was found by Cheapflights users on 9/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 10/245:14 pm -
1 stop5h 30m
Wed 10/286:10 am -
1 stop8h 08m
Deal found 9/3![United Airlines logo]()
$400
This American Airlines deal was found by Cheapflights users on 9/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 9/141:42 pm -
1 stop4h 50m
Tue 9/226:40 pm -
1 stop4h 52m
Deal found 9/4![American Airlines logo]()
$410
Best flights from Biloxi to ColumbusDiscover carefully curated flight deals from Biloxi to Columbus that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated September 9, 2026.
Discover carefully curated flight deals from Biloxi to Columbus that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated September 9, 2026.
This United Airlines deal was found by Cheapflights users on 9/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 9/194:59 pm -
1 stop5h 45m
Wed 9/235:20 am -
2 stops9h 04m
Deal found 9/4![United Airlines logo]()
$374
This American Airlines deal was found by Cheapflights users on 9/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 9/145:42 pm -
1 stop5h 11m
Tue 9/229:16 am -
2 stops8h 56m
Deal found 9/4![American Airlines logo]()
$492
This United Airlines deal was found by Cheapflights users on 9/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/25:14 pm -
1 stop5h 30m
Sun 10/45:20 am -
2 stops9h 05m
Deal found 9/7![United Airlines logo]()
$389
This United Airlines deal was found by Cheapflights users on 9/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 10/245:14 pm -
1 stop5h 30m
Wed 10/286:10 am -
1 stop8h 08m
Deal found 9/3![United Airlines logo]()
$400
Last-minute flights from Biloxi to ColumbusDiscover last-minute flight deals from Biloxi to Columbus. Data last updated September 9, 2026 and is based on user searches.
Discover last-minute flight deals from Biloxi to Columbus. Data last updated September 9, 2026 and is based on user searches.
This American Airlines deal was found by Cheapflights users on 9/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 9/141:42 pm -
1 stop4h 50m
Tue 9/226:40 pm -
1 stop4h 52m
Deal found 9/4![American Airlines logo]()
$410
This United Airlines deal was found by Cheapflights users on 9/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 9/194:59 pm -
1 stop5h 45m
Wed 9/236:30 am -
1 stop7h 54m
Deal found 9/4![United Airlines logo]()
$369
This American Airlines deal was found by Cheapflights users on 9/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/25:42 pm -
1 stop5h 11m
Sun 10/46:00 am -
1 stop5h 40m
Deal found 9/7![American Airlines logo]()
$347
This United Airlines deal was found by Cheapflights users on 9/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/25:14 pm -
1 stop5h 30m
Sun 10/45:20 am -
2 stops9h 05m
Deal found 9/7![United Airlines logo]()
$389
This Delta deal was found by Cheapflights users on 9/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/96:05 pm -
1 stop5h 39m
Sun 10/116:00 am -
1 stop4h 17m
Deal found 9/8![Delta logo]()
$367
This United Airlines deal was found by Cheapflights users on 9/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 10/245:14 pm -
1 stop5h 30m
Wed 10/286:10 am -
1 stop8h 08m
Deal found 9/3![United Airlines logo]()
$400
One-way flights from Biloxi to ColumbusSearch for one-way flight options from Biloxi to Columbus. Find affordable one-way fares based on user searches. Data last updated September 9, 2026.
Search for one-way flight options from Biloxi to Columbus. Find affordable one-way fares based on user searches. Data last updated September 9, 2026.
This Kiwi.com deal was found by Cheapflights users on 9/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 9/286:46 pm -
2 stops23h 09m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 9/5![Multiple Airlines logo]()
$130
This Kiwi.com deal was found by Cheapflights users on 9/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/26:46 pm -
2 stops25h 08m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 9/5![Breeze Airways logo]()
$171
This Kiwi.com deal was found by Cheapflights users on 9/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/26:46 pm -
3 stops22h 41m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 9/5![Multiple Airlines logo]()
$210
This Kiwi.com deal was found by Cheapflights users on 9/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/17:45 pm -
1 stop23h 46m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 9/5![Multiple Airlines logo]()
$220
This Delta deal was found by Cheapflights users on 9/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/96:05 pm -
1 stop5h 39m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 9/8![Delta logo]()
$245
This Kiwi.com deal was found by Cheapflights users on 9/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/17:45 pm -
3 stops22h 10m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 9/5![Breeze Airways logo]()
$250
This Delta deal was found by Cheapflights users on 9/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 9/264:00 pm -
1 stop6h 36m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 9/5![Delta logo]()
$262
This United Airlines deal was found by Cheapflights users on 9/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 9/292:00 pm -
2 stops8h 59m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 9/5![United Airlines logo]()
$284
This United Airlines deal was found by Cheapflights users on 9/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 9/275:14 pm -
1 stop5h 30m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 9/5![United Airlines logo]()
$316
This United Airlines deal was found by Cheapflights users on 9/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 9/262:00 pm -
2 stops8h 54m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 9/5![United Airlines logo]()
$375
Find flight deals from Biloxi to Columbus
Keep the following information in mind while searching for Biloxi to Columbus flight deals. Data was last updated September 9, 2026.
Round-trip from | $347 (American Airlines) |
|---|---|
One-way from | $130 (Kiwi.com) |
Popular in | April |
Cheapest in | August |
Average price | $426 |
Cheapflights Fare Finder
Customize your flight search to find flights from Biloxi to Columbus that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 7,457,451 searches. Data last updated September 9, 2026.
Use the filters below to find and compare flights from Biloxi to Columbus that are best for you.
Fly from
Fly to
Route
Depart
Return
Cheapest round-trip
GulfportColumbus
GPT Gulfport Biloxi Regional - CMH Columbus
GPTCMH
Gulfport Biloxi Regional
Fri 10/9
6:05 pm-12:44 am
1 stop5h 39m
Columbus
Wed 12/31
12:00 am-11:00 pm
Nonstop0h 00m
$245
GulfportColumbus
GPT Gulfport Biloxi Regional - CMH Columbus
GPTCMH
Gulfport Biloxi Regional
Fri 10/2
5:59 pm-12:15 am
1 stop5h 16m
Columbus
Wed 12/31
12:00 am-11:00 pm
Nonstop0h 00m
$262
GulfportColumbus
GPT Gulfport Biloxi Regional - CMH Columbus
GPTCMH
Gulfport Biloxi Regional
Sat 9/26
4:00 pm-11:36 pm
1 stop6h 36m
Columbus
Wed 12/31
12:00 am-11:00 pm
Nonstop0h 00m
$262
Quickest round-trip
GulfportColumbus
GPT Gulfport Biloxi Regional - CMH Columbus
GPTCMH
Gulfport Biloxi Regional
Wed 9/30
1:59 pm-8:04 pm
1 stop5h 05m
Columbus
Wed 12/31
12:00 am-11:00 pm
Nonstop0h 00m
$262
GulfportColumbus
GPT Gulfport Biloxi Regional - CMH Columbus
GPTCMH
Gulfport Biloxi Regional
Sun 9/27
5:14 pm-11:44 pm
1 stop5h 30m
Columbus
Wed 12/31
12:00 am-11:00 pm
Nonstop0h 00m
$316
GulfportColumbus
GPT Gulfport Biloxi Regional - CMH Columbus
GPTCMH
Gulfport Biloxi Regional
Sat 9/19
4:59 pm-11:44 pm
1 stop5h 45m
Columbus
Wed 9/23
5:20 am-1:24 pm
2 stops9h 04m
$374
GulfportColumbus
GPT Gulfport Biloxi Regional - CMH Columbus
GPTCMH
Gulfport Biloxi Regional
Fri 10/2
5:14 pm-11:44 pm
1 stop5h 30m
Columbus
Sun 10/4
5:20 am-1:25 pm
2 stops9h 05m
$389
GulfportColumbus
GPT Gulfport Biloxi Regional - CMH Columbus
GPTCMH
Gulfport Biloxi Regional
Sat 10/24
5:14 pm-11:44 pm
1 stop5h 30m
Columbus
Wed 10/28
6:10 am-1:18 pm
1 stop8h 08m
$400
GulfportColumbus
GPT Gulfport Biloxi Regional - CMH Columbus
GPTCMH
Gulfport Biloxi Regional
Tue 9/29
5:14 pm-1:14 pm
3 stops19h 00m
Columbus
Wed 12/31
12:00 am-11:00 pm
Nonstop0h 00m
$446
GulfportColumbus
GPT Gulfport Biloxi Regional - CMH Columbus
GPTCMH
Gulfport Biloxi Regional
Fri 10/9
2:00 pm-11:54 pm
2 stops8h 54m
Columbus
Wed 12/31
12:00 am-11:00 pm
Nonstop0h 00m
$467
Showing 1-10 of 12 resultsSorted by cheapest first
Best time to book a flight from Biloxi to Columbus
Have a flexible travel schedule? Discover the best time to fly to Columbus from Biloxi with our price prediction graph.
GPT-CMH
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.
Cheapflights Insights
Everything you need to know about your flight from Biloxi to Columbus
B1L-C01
GPT-CMH
No data available for this route at this time. Please check back soon.
Reviews of airlines servicing Columbus
Get insights into the airlines that provide service to Columbus. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Columbus. Reviews last updated September 9, 2026.
See what other customers who have flown with Delta and American Airlines from Biloxi to Columbus have to say. Users can see the overall rating for each airline as well as how each is rated in terms of entertainment options, comfort, food, crew/service, and boarding process.
Comfort
7.8
Overall
7.8
Crew
8.5
Food
7.2
Boarding
8.1
Entertainment
7.8
Reviews
1 / 20
8.0
ExcellentJorge,Aug 2026
TPA - ATL
Comfort
7.8
Overall
7.8
Crew
8.5
Food
7.2
Boarding
8.1
Entertainment
7.8
Reviews
1 / 20
8.0
ExcellentJorge,Aug 2026
TPA - ATL
Comfort
7.8
Overall
7.8
Crew
8.5
Food
7.2
Boarding
8.1
Entertainment
7.8
Reviews
1 / 20
8.0
ExcellentJorge,Aug 2026
TPA - ATL
Related info for your journey
Find useful and relevant information for your journey from Biloxi to Columbus. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.
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Alternative routes for Biloxi to Columbus
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Complete your trip
Complete your trip to Columbus by adding a car rental and/or hotel reservation to your travel itinerary.
Search flights from Biloxi to Columbus by cabin class
Find flights from Biloxi to Columbus, based on your preferred cabin class, be it economy, premium economy, business, or first class.
Biloxi and Columbus flights
Browse other Biloxi and Columbus flight options. Last updated on September 9, 2026.
Popular flight searches
Check out other popular destinations found by fellow travelers in 2026
Top 4 airlines flying from Biloxi to Columbus
Discover the top 4 airlines that operate flights from Biloxi to Columbus. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 7,457,451 searches. Data last updated September 9, 2026.
| Airline | Cheapest | Average | Flexibility | On-time |
|---|---|---|---|---|
| Cheapest$248 | Average$391 | FlexibilityNo cancel fee | On-timeN/A | |
| Cheapest$273 | Average$429 | FlexibilityNo cancel fee | On-time71% | |
| Cheapest$276 | Average$406 | FlexibilityNo cancel fee | On-time63% | |
| Cheapest$278 | Average$371 | FlexibilityNo cancel fee | On-time69% |