$143+ Cheap flights from Columbus to Biloxi, MS
This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 6/14. Fares are subject to change and may not be available on all flights or dates of travel.
CMH — MSY
May 28 — Jun 41
Round-trip
1 adult, Economy
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Find cheap flights from Columbus to Biloxi with Cheapflights
1. Tell us where you want to go
Enter your travel information like dates, passengers, trip type (one-way or round trip), and preferred cabin class then click “Find deals”2. Select your favorite providers
We find the providers serving your travel needs. Choose up to four travel providers to compare side-by-side for flights, hotels, or car rentals.3. Compare prices and book
Review each provider’s pricing and select the best option for you! Book through your favorite provider’s website for a seamless experience.Cheap flight deals from Columbus to Biloxi
Cheapest
Best
Last-minute
One-way
Cheapest flights from Columbus to BiloxiExplore the most affordable flight options available from Columbus to Biloxi. Find the lowest fares from popular airlines and budget airlines, with prices last updated on April 28, 2026.
Explore the most affordable flight options available from Columbus to Biloxi. Find the lowest fares from popular airlines and budget airlines, with prices last updated on April 28, 2026.
This Kiwi.com deal was found by Cheapflights users on 4/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 5/211:37 pm
CMH
- GPT
1 stop6h 33m
Multiple Airlines
Thu 5/287:50 pm
GPT
- CMH
1 stop15h 52m
Multiple Airlines
Deal found 4/23![Multiple Airlines logo]()
$292
This Delta deal was found by Cheapflights users on 4/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 5/284:49 pm
CMH
- GPT
1 stop6h 02m
Delta
Tue 6/26:02 pm
GPT
- CMH
1 stop5h 23m
Delta
Deal found 4/23![Delta logo]()
$311
This American Airlines deal was found by Cheapflights users on 4/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 5/283:45 pm
CMH
- GPT
2 stops9h 16m
American Airlines
Tue 6/26:38 pm
GPT
- CMH
1 stop4h 14m
American Airlines
Deal found 4/27![American Airlines logo]()
$316
This United Airlines deal was found by Cheapflights users on 4/24. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 8/166:30 am
CMH
- GPT
1 stop7h 56m
United Airlines
Sat 8/225:15 pm
GPT
- CMH
1 stop5h 27m
United Airlines
Deal found 4/24![United Airlines logo]()
$320
This Kiwi.com deal was found by Cheapflights users on 4/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 5/101:37 pm
CMH
- GPT
1 stop6h 33m
Multiple Airlines
Thu 5/147:50 pm
GPT
- CMH
1 stop15h 52m
Multiple Airlines
Deal found 4/25![Multiple Airlines logo]()
$325
This Kiwi.com deal was found by Cheapflights users on 4/24. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 5/71:37 pm
CMH
- GPT
1 stop6h 33m
Multiple Airlines
Mon 5/115:31 pm
GPT
- CMH
2 stops17h 51m
Multiple Airlines
Deal found 4/24![Multiple Airlines logo]()
$348
This American Airlines deal was found by Cheapflights users on 4/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 5/305:40 pm
CMH
- GPT
1 stop7h 21m
American Airlines
Tue 6/305:00 am
GPT
- CMH
1 stop8h 02m
American Airlines
Deal found 4/25![American Airlines logo]()
$367
This Delta deal was found by Cheapflights users on 4/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 5/286:05 am
CMH
- GPT
1 stop4h 16m
Delta
Mon 6/16:02 pm
GPT
- CMH
1 stop5h 28m
Delta
Deal found 4/23![Delta logo]()
$369
Best flights from Columbus to BiloxiDiscover carefully curated flight deals from Columbus to Biloxi that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated April 28, 2026.
Discover carefully curated flight deals from Columbus to Biloxi that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated April 28, 2026.
This Delta deal was found by Cheapflights users on 4/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 8/410:00 am
CMH
- GPT
1 stop4h 05m
Delta
Sat 8/86:30 am
GPT
- CMH
1 stop6h 08m
Delta
Deal found 4/25![Delta logo]()
$311
This American Airlines deal was found by Cheapflights users on 4/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 5/283:45 pm
CMH
- GPT
2 stops9h 16m
American Airlines
Tue 6/26:38 pm
GPT
- CMH
1 stop4h 14m
American Airlines
Deal found 4/26![American Airlines logo]()
$316
This Kiwi.com deal was found by Cheapflights users on 4/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 5/101:37 pm
CMH
- GPT
1 stop6h 33m
Multiple Airlines
Thu 5/147:50 pm
GPT
- CMH
1 stop15h 52m
Multiple Airlines
Deal found 4/25![Multiple Airlines logo]()
$325
This United Airlines deal was found by Cheapflights users on 4/24. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 8/166:30 am
CMH
- GPT
1 stop7h 56m
United Airlines
Sat 8/222:00 pm
GPT
- CMH
2 stops8h 59m
United Airlines
Deal found 4/24![United Airlines logo]()
$334
This Delta deal was found by Cheapflights users on 4/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 5/284:49 pm
CMH
- GPT
1 stop6h 02m
Delta
Tue 6/26:02 pm
GPT
- CMH
1 stop5h 23m
Delta
Deal found 4/23![Delta logo]()
$311
This American Airlines deal was found by Cheapflights users on 4/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 5/305:40 pm
CMH
- GPT
1 stop7h 21m
American Airlines
Tue 6/305:00 am
GPT
- CMH
1 stop8h 02m
American Airlines
Deal found 4/25![American Airlines logo]()
$367
This United Airlines deal was found by Cheapflights users on 4/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 5/137:00 am
CMH
- GPT
2 stops10h 13m
United Airlines
Sat 5/162:00 pm
GPT
- CMH
1 stop7h 11m
United Airlines
Deal found 4/26![United Airlines logo]()
$369
This Delta deal was found by Cheapflights users on 4/24. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 5/284:49 pm
CMH
- GPT
1 stop6h 02m
Delta
Wed 6/36:02 pm
GPT
- CMH
1 stop5h 23m
Delta
Deal found 4/24![Delta logo]()
$369
This Delta deal was found by Cheapflights users on 4/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 5/286:05 am
CMH
- GPT
1 stop4h 16m
Delta
Mon 6/16:02 pm
GPT
- CMH
1 stop5h 28m
Delta
Deal found 4/23![Delta logo]()
$369
Last-minute flights from Columbus to BiloxiDiscover last-minute flight deals from Columbus to Biloxi. Data last updated April 28, 2026 and is based on user searches.
Discover last-minute flight deals from Columbus to Biloxi. Data last updated April 28, 2026 and is based on user searches.
This Kiwi.com deal was found by Cheapflights users on 4/24. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 5/71:37 pm
CMH
- GPT
1 stop6h 33m
Multiple Airlines
Mon 5/115:31 pm
GPT
- CMH
2 stops17h 51m
Multiple Airlines
Deal found 4/24![Multiple Airlines logo]()
$348
This Kiwi.com deal was found by Cheapflights users on 4/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 5/101:37 pm
CMH
- GPT
1 stop6h 33m
Multiple Airlines
Thu 5/147:50 pm
GPT
- CMH
1 stop15h 52m
Multiple Airlines
Deal found 4/25![Multiple Airlines logo]()
$325
This Kiwi.com deal was found by Cheapflights users on 4/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 5/211:37 pm
CMH
- GPT
1 stop6h 33m
Multiple Airlines
Thu 5/287:50 pm
GPT
- CMH
1 stop15h 52m
Multiple Airlines
Deal found 4/23![Multiple Airlines logo]()
$292
This Delta deal was found by Cheapflights users on 4/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 5/284:49 pm
CMH
- GPT
1 stop6h 02m
Delta
Tue 6/26:02 pm
GPT
- CMH
1 stop5h 23m
Delta
Deal found 4/23![Delta logo]()
$311
This American Airlines deal was found by Cheapflights users on 4/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 5/283:45 pm
CMH
- GPT
2 stops9h 16m
American Airlines
Tue 6/26:38 pm
GPT
- CMH
1 stop4h 14m
American Airlines
Deal found 4/27![American Airlines logo]()
$316
This Delta deal was found by Cheapflights users on 4/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 5/286:05 am
CMH
- GPT
1 stop4h 16m
Delta
Mon 6/16:02 pm
GPT
- CMH
1 stop5h 28m
Delta
Deal found 4/23![Delta logo]()
$369
This American Airlines deal was found by Cheapflights users on 4/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 5/283:45 pm
CMH
- GPT
2 stops9h 16m
American Airlines
Mon 6/16:38 pm
GPT
- CMH
1 stop4h 14m
American Airlines
Deal found 4/27![American Airlines logo]()
$374
This American Airlines deal was found by Cheapflights users on 4/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 5/305:40 pm
CMH
- GPT
1 stop7h 21m
American Airlines
Tue 6/305:00 am
GPT
- CMH
1 stop8h 02m
American Airlines
Deal found 4/25![American Airlines logo]()
$367
One-way flights from Columbus to BiloxiSearch for one-way flight options from Columbus to Biloxi. Find affordable one-way fares based on user searches. Data last updated April 28, 2026.
Search for one-way flight options from Columbus to Biloxi. Find affordable one-way fares based on user searches. Data last updated April 28, 2026.
This Kiwi.com deal was found by Cheapflights users on 4/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 6/141:37 pm
CMH
- GPT
1 stop6h 33m
Multiple Airlines
Deal found 4/27![Multiple Airlines logo]()
$143
This Delta deal was found by Cheapflights users on 4/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 5/164:59 pm
CMH
- GPT
1 stop5h 52m
Delta
Deal found 4/27![Delta logo]()
$301
This United Airlines deal was found by Cheapflights users on 4/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 5/165:36 am
CMH
- GPT
2 stops8h 45m
United Airlines
Deal found 4/27![United Airlines logo]()
$306
This Delta deal was found by Cheapflights users on 4/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 5/25:00 pm
CMH
- GPT
1 stop6h 13m
Delta
Deal found 4/27![Delta logo]()
$382
This United Airlines deal was found by Cheapflights users on 4/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 5/27:00 am
CMH
- GPT
2 stops10h 13m
United Airlines
Deal found 4/27![United Airlines logo]()
$387
Find flight deals from Columbus to Biloxi
Keep the following information in mind while searching for Columbus to Biloxi flight deals. Data was last updated April 28, 2026.
Round-trip from | $292 (Kiwi.com) |
|---|---|
One-way from | $143 (Kiwi.com) |
Popular in | July |
Cheapest in | January |
Average price | $339 |
Cheapflights Fare Finder
Customize your flight search to find flights from Columbus to Biloxi that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated April 28, 2026.
Use the filters below to find and compare flights from Columbus to Biloxi that are best for you.
Fly from
Fly to
Route
Depart
Return
Cheapest round-trip
ColumbusGulfport
CMH - GPT
CMHGPT
Columbus
Tue 8/4
10:00 am-1:05 pm
1 stop4h 05m
Gulfport Biloxi Regional
Sat 8/8
6:30 am-1:38 pm
1 stop6h 08m
$311
ColumbusGulfport
CMH - GPT
CMHGPT
Columbus
Thu 5/28
4:49 pm-9:51 pm
1 stop6h 02m
Gulfport Biloxi Regional
Tue 6/2
6:02 pm-12:25 am
1 stop5h 23m
$311
ColumbusGulfport
CMH - GPT
CMHGPT
Columbus
Thu 5/28
3:45 pm-12:01 am
2 stops9h 16m
Gulfport Biloxi Regional
Tue 6/2
6:38 pm-11:52 pm
1 stop4h 14m
$316
ColumbusGulfport
CMH - GPT
CMHGPT
Columbus
Sun 5/10
1:37 pm-7:10 pm
1 stop6h 33m
Gulfport Biloxi Regional
Thu 5/14
7:50 pm-12:42 pm
1 stop15h 52m
$325
ColumbusGulfport
CMH - GPT
CMHGPT
Columbus
Sun 8/16
6:30 am-1:26 pm
1 stop7h 56m
Gulfport Biloxi Regional
Sat 8/22
2:00 pm-11:59 pm
2 stops8h 59m
$334
ColumbusGulfport
CMH - GPT
CMHGPT
Columbus
Sat 5/30
5:40 pm-12:01 am
1 stop7h 21m
Gulfport Biloxi Regional
Tue 6/30
5:00 am-2:02 pm
1 stop8h 02m
$367
ColumbusGulfport
CMH - GPT
CMHGPT
Columbus
Wed 5/13
7:00 am-4:13 pm
2 stops10h 13m
Gulfport Biloxi Regional
Sat 5/16
2:00 pm-10:11 pm
1 stop7h 11m
$369
ColumbusGulfport
CMH - GPT
CMHGPT
Columbus
Thu 5/28
4:49 pm-9:51 pm
1 stop6h 02m
Gulfport Biloxi Regional
Wed 6/3
6:02 pm-12:25 am
1 stop5h 23m
$369
Quickest round-trip
ColumbusGulfport
CMH - GPT
CMHGPT
Columbus
Thu 5/28
6:05 am-9:21 am
1 stop4h 16m
Gulfport Biloxi Regional
Mon 6/1
6:02 pm-12:30 am
1 stop5h 28m
$369
Cheapest one-way
ColumbusGulfport
CMH - GPT
CMHGPT
Columbus
Sun 6/14
1:37 pm-7:10 pm
1 stop6h 33m
$143
Showing 1-10 of 13 resultsSorted by cheapest first
Best time to book a flight from Columbus to Biloxi
Have a flexible travel schedule? Discover the best time to fly to Biloxi from Columbus with our price prediction graph.
CMH-GPT
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.
Cheapflights Insights
Everything you need to know about your flight from Columbus to Biloxi
C01-B1L
CMH-GPT
What is the cheapest time of day to fly from CMH to B1L?
Find hourly flight availability from Columbus to Biloxi. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated April 28, 2026.
Unlike in the afternoon, when flights are generally more expensive, you can save up to 59% on flights from Columbus to Biloxi by exploring options for tickets at noon.
How much does it cost to fly round-trip from Columbus to Biloxi?
Reviews of airlines servicing Biloxi
Get insights into the airlines that provide service to Biloxi. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Biloxi. Reviews last updated April 28, 2026.
See what other customers who have flown with Delta,United Airlines, andAmerican Airlines from Columbus to Biloxi have to say. You can also see how each airline compares in terms of entertainment options, comfort, food, crew/service, and boarding process.
Entertainment
7.8
Crew
8.5
Boarding
8.1
Food
7.2
Overall
7.9
Comfort
7.9
Reviews
1 / 20
6.0
GoodJim,Nov 2025
AVL - ATL
Entertainment
7.8
Crew
8.5
Boarding
8.1
Food
7.2
Overall
7.9
Comfort
7.9
Reviews
1 / 20
6.0
GoodJim,Nov 2025
AVL - ATL
Entertainment
7.8
Crew
8.5
Boarding
8.1
Food
7.2
Overall
7.9
Comfort
7.9
Reviews
1 / 20
6.0
GoodJim,Nov 2025
AVL - ATL
Entertainment
7.8
Crew
8.5
Boarding
8.1
Food
7.2
Overall
7.9
Comfort
7.9
Reviews
1 / 20
6.0
GoodJim,Nov 2025
AVL - ATL
Related info for your journey
Find useful and relevant information for your journey from Columbus to Biloxi. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.
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Alternative routes for Columbus to Biloxi
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Complete your trip
Complete your trip to Biloxi by adding a car rental and/or hotel reservation to your travel itinerary.
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Find flights from Columbus to Biloxi, based on your preferred cabin class, be it economy, premium economy, business, or first class.
Columbus and Biloxi flights
Browse other Columbus and Biloxi flight options. Last updated on April 28, 2026.
Popular flight searches
Check out other popular destinations found by fellow travelers in 2026
Top 6 airlines flying from Columbus to Biloxi
Discover the top 6 airlines that operate flights from Columbus to Biloxi. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated April 28, 2026.
| Airline | Cheapest | Average | Flexibility | On-time |
|---|---|---|---|---|
| Cheapest$99 | Average$185 | FlexibilityNo cancel fee | On-timeN/A | |
| Cheapest$106 | Average$182 | FlexibilityNo cancel fee | On-time65% | |
| Cheapest$210 | Average$386 | FlexibilityNo cancel fee | On-timeN/A | |
| Cheapest$248 | Average$396 | FlexibilityNo cancel fee | On-time69% | |
| Cheapest$248 | Average$431 | FlexibilityNo cancel fee | On-time71% | |
| Cheapest$258 | Average$394 | FlexibilityNo cancel fee | On-time63% |