$208+ Cheap flights from Columbus to Biloxi, MS
This is the cheapest round-trip flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 10/1. Fares are subject to change and may not be available on all flights or dates of travel.
CMH — MSY
Oct 12 — Oct 191
Round-trip
1 adult, Economy
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1. Tell us where you want to go
Enter your travel information like dates, passengers, trip type (one-way or round trip), and preferred cabin class then click “Find deals”2. Select your favorite providers
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Review each provider’s pricing and select the best option for you! Book through your favorite provider’s website for a seamless experience.Cheap flight deals from Columbus to Biloxi
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Best
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One-way
Cheapest flights from Columbus to BiloxiExplore the most affordable flight options available from Columbus to Biloxi. Find the lowest fares from popular airlines and budget airlines, with prices last updated on September 12, 2026.
Explore the most affordable flight options available from Columbus to Biloxi. Find the lowest fares from popular airlines and budget airlines, with prices last updated on September 12, 2026.
This American Airlines deal was found by Cheapflights users on 9/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 12/315:53 pm -
1 stop7h 04m
Tue 1/56:00 am -
1 stop6h 17m
Deal found 9/9![American Airlines logo]()
$334
This Delta deal was found by Cheapflights users on 9/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 11/101:06 pm -
1 stop5h 13m
Fri 11/136:04 pm -
1 stop18h 02m
Deal found 9/10![Delta logo]()
$344
This Delta deal was found by Cheapflights users on 9/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 11/56:00 am -
1 stop4h 17m
Mon 11/96:04 pm -
1 stop5h 26m
Deal found 9/9![Delta logo]()
$347
This United Airlines deal was found by Cheapflights users on 9/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/295:15 am -
2 stops9h 03m
Sun 11/14:55 pm -
1 stop5h 49m
Deal found 9/10![United Airlines logo]()
$353
This Delta deal was found by Cheapflights users on 9/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 10/76:00 am -
1 stop4h 17m
Mon 10/126:05 pm -
1 stop5h 39m
Deal found 9/7![Delta logo]()
$354
This Delta deal was found by Cheapflights users on 9/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 11/98:05 am -
1 stop6h 00m
Fri 11/136:04 pm -
1 stop18h 02m
Deal found 9/10![Delta logo]()
$357
This American Airlines deal was found by Cheapflights users on 9/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 9/256:00 am -
1 stop5h 40m
Mon 9/285:42 pm -
1 stop5h 11m
Deal found 9/7![American Airlines logo]()
$364
This United Airlines deal was found by Cheapflights users on 9/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 9/256:30 am -
1 stop5h 48m
Tue 9/295:14 pm -
1 stop5h 30m
Deal found 9/10![United Airlines logo]()
$369
Best flights from Columbus to BiloxiDiscover carefully curated flight deals from Columbus to Biloxi that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated September 12, 2026.
Discover carefully curated flight deals from Columbus to Biloxi that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated September 12, 2026.
This Delta deal was found by Cheapflights users on 9/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 11/56:00 am -
1 stop4h 17m
Mon 11/96:04 pm -
1 stop5h 26m
Deal found 9/9![Delta logo]()
$347
This United Airlines deal was found by Cheapflights users on 9/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 10/310:30 am -
2 stops10h 08m
Thu 10/85:14 pm -
1 stop5h 30m
Deal found 9/10![United Airlines logo]()
$413
This Delta deal was found by Cheapflights users on 9/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 12/115:47 pm -
1 stop5h 10m
Mon 12/146:09 pm -
1 stop5h 24m
Deal found 9/7![Delta logo]()
$367
This United Airlines deal was found by Cheapflights users on 9/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 9/309:15 am -
2 stops11h 23m
Sat 10/35:14 pm -
1 stop5h 30m
Deal found 9/10![United Airlines logo]()
$419
This Delta deal was found by Cheapflights users on 9/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/236:00 am -
1 stop4h 17m
Sun 10/256:05 pm -
1 stop5h 39m
Deal found 9/8![Delta logo]()
$419
This United Airlines deal was found by Cheapflights users on 9/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 10/77:17 am -
2 stops9h 55m
Tue 10/135:14 pm -
1 stop5h 30m
Deal found 9/9![United Airlines logo]()
$432
This United Airlines deal was found by Cheapflights users on 9/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 2/56:07 am -
2 stops10h 55m
Thu 2/111:54 pm -
2 stops8h 42m
Deal found 9/11![United Airlines logo]()
$469
Last-minute flights from Columbus to BiloxiDiscover last-minute flight deals from Columbus to Biloxi. Data last updated September 12, 2026 and is based on user searches.
Discover last-minute flight deals from Columbus to Biloxi. Data last updated September 12, 2026 and is based on user searches.
This United Airlines deal was found by Cheapflights users on 9/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 9/186:30 am -
1 stop7h 54m
Mon 9/214:59 pm -
1 stop5h 45m
Deal found 9/7![United Airlines logo]()
$399
This American Airlines deal was found by Cheapflights users on 9/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 9/246:00 am -
1 stop5h 40m
Mon 9/285:42 pm -
1 stop5h 11m
Deal found 9/9![American Airlines logo]()
$381
This American Airlines deal was found by Cheapflights users on 9/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 9/256:00 am -
1 stop5h 40m
Mon 9/285:42 pm -
1 stop5h 11m
Deal found 9/7![American Airlines logo]()
$364
This United Airlines deal was found by Cheapflights users on 9/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 9/256:30 am -
1 stop5h 48m
Tue 9/295:14 pm -
1 stop5h 30m
Deal found 9/10![United Airlines logo]()
$369
This American Airlines deal was found by Cheapflights users on 9/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 10/312:43 pm -
1 stop5h 29m
Thu 10/86:42 pm -
1 stop4h 39m
Deal found 9/10![American Airlines logo]()
$347
This Delta deal was found by Cheapflights users on 9/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 10/76:00 am -
1 stop4h 17m
Tue 10/136:05 pm -
1 stop5h 39m
Deal found 9/9![Delta logo]()
$334
This Delta deal was found by Cheapflights users on 9/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 10/76:00 am -
1 stop4h 17m
Mon 10/126:05 pm -
1 stop5h 39m
Deal found 9/7![Delta logo]()
$354
This United Airlines deal was found by Cheapflights users on 9/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/295:15 am -
2 stops9h 03m
Sun 11/14:55 pm -
1 stop5h 49m
Deal found 9/10![United Airlines logo]()
$353
One-way flights from Columbus to BiloxiSearch for one-way flight options from Columbus to Biloxi. Find affordable one-way fares based on user searches. Data last updated September 12, 2026.
Search for one-way flight options from Columbus to Biloxi. Find affordable one-way fares based on user searches. Data last updated September 12, 2026.
This Kiwi.com deal was found by Cheapflights users on 9/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/19:09 am -
2 stops24h 42m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 9/10![Breeze Airways logo]()
$208
This United Airlines deal was found by Cheapflights users on 9/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected ” under the list of providers to see comparable flight deals.
Thu 10/16:30 am -
1 stop7h 55m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 9/10![United Airlines logo]()
$228
This Delta deal was found by Cheapflights users on 9/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 10/116:00 am -
1 stop4h 17m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 9/8![Delta logo]()
$269
This Kiwi.com deal was found by Cheapflights users on 9/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/17:50 pm -
3 stops23h 16m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 9/10![Multiple Airlines logo]()
$394
This United Airlines deal was found by Cheapflights users on 9/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 10/117:17 am -
2 stops9h 55m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 9/8![United Airlines logo]()
$408
Find flight deals from Columbus to Biloxi
Keep the following information in mind while searching for Columbus to Biloxi flight deals. Data was last updated September 12, 2026.
Round-trip from | $321 (American Airlines) |
|---|---|
One-way from | $208 (Kiwi.com) |
Popular in | July |
Cheapest in | August |
Average price | $366 |
Cheapflights Fare Finder
Customize your flight search to find flights from Columbus to Biloxi that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 7,457,451 searches. Data last updated September 12, 2026.
Use the filters below to find and compare flights from Columbus to Biloxi that are best for you.
Fly from
Fly to
Route
Depart
Return
Cheapest round-trip
ColumbusGulfport
CMH Columbus - GPT Gulfport Biloxi Regional
CMHGPT
Columbus
Thu 10/1
9:09 am-8:51 am
2 stops24h 42m
Gulfport Biloxi Regional
Wed 12/31
12:00 am-1:00 am
Nonstop0h 00m
$208
ColumbusGulfport
CMH Columbus - GPT Gulfport Biloxi Regional
CMHGPT
Columbus
Thu 10/1
6:30 am-1:25 pm
1 stop7h 55m
Gulfport Biloxi Regional
Wed 12/31
12:00 am-1:00 am
Nonstop0h 00m
$228
Quickest round-trip
ColumbusGulfport
CMH Columbus - GPT Gulfport Biloxi Regional
CMHGPT
Columbus
Sun 10/11
6:00 am-9:17 am
1 stop4h 17m
Gulfport Biloxi Regional
Wed 12/31
12:00 am-1:00 am
Nonstop0h 00m
$269
ColumbusGulfport
CMH Columbus - GPT Gulfport Biloxi Regional
CMHGPT
Columbus
Thu 11/5
6:00 am-9:17 am
1 stop4h 17m
Gulfport Biloxi Regional
Mon 11/9
6:04 pm-12:30 am
1 stop5h 26m
$347
ColumbusGulfport
CMH Columbus - GPT Gulfport Biloxi Regional
CMHGPT
Columbus
Fri 12/11
5:47 pm-9:57 pm
1 stop5h 10m
Gulfport Biloxi Regional
Mon 12/14
6:09 pm-12:33 am
1 stop5h 24m
$367
ColumbusGulfport
CMH Columbus - GPT Gulfport Biloxi Regional
CMHGPT
Columbus
Thu 10/1
7:50 pm-6:06 pm
3 stops23h 16m
Gulfport Biloxi Regional
Wed 12/31
12:00 am-1:00 am
Nonstop0h 00m
$394
ColumbusGulfport
CMH Columbus - GPT Gulfport Biloxi Regional
CMHGPT
Columbus
Sun 10/11
7:17 am-4:12 pm
2 stops9h 55m
Gulfport Biloxi Regional
Wed 12/31
12:00 am-1:00 am
Nonstop0h 00m
$408
ColumbusGulfport
CMH Columbus - GPT Gulfport Biloxi Regional
CMHGPT
Columbus
Sat 10/3
10:30 am-7:38 pm
2 stops10h 08m
Gulfport Biloxi Regional
Thu 10/8
5:14 pm-11:44 pm
1 stop5h 30m
$413
ColumbusGulfport
CMH Columbus - GPT Gulfport Biloxi Regional
CMHGPT
Columbus
Wed 9/30
9:15 am-7:38 pm
2 stops11h 23m
Gulfport Biloxi Regional
Sat 10/3
5:14 pm-11:44 pm
1 stop5h 30m
$419
ColumbusGulfport
CMH Columbus - GPT Gulfport Biloxi Regional
CMHGPT
Columbus
Fri 10/23
6:00 am-9:17 am
1 stop4h 17m
Gulfport Biloxi Regional
Sun 10/25
6:05 pm-12:44 am
1 stop5h 39m
$419
Showing 1-10 of 12 resultsSorted by cheapest first
Best time to book a flight from Columbus to Biloxi
Have a flexible travel schedule? Discover the best time to fly to Biloxi from Columbus with our price prediction graph.
CMH-GPT
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.
Cheapflights Insights
Everything you need to know about your flight from Columbus to Biloxi
C01-B1L
CMH-GPT
What is the cheapest time of day to fly from CMH to B1L?
Find hourly flight availability from Columbus to Biloxi. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated September 12, 2026.
Unlike in the afternoon, when flights are generally more expensive, you can save up to 57% on flights from Columbus to Biloxi by exploring options for tickets at noon.
Reviews of airlines servicing Biloxi
Get insights into the airlines that provide service to Biloxi. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Biloxi. Reviews last updated September 12, 2026.
See what other customers who have flown with Delta and American Airlines from Columbus to Biloxi have to say. You can also see how each airline compares in terms of entertainment options, comfort, food, crew/service, and boarding process.
Overall
7.8
Boarding
8.1
Comfort
7.8
Crew
8.5
Entertainment
7.8
Food
7.2
Reviews
1 / 20
4.0
OkayJennifer,Sep 2026
ORD - LGA
Overall
7.8
Boarding
8.1
Comfort
7.8
Crew
8.5
Entertainment
7.8
Food
7.2
Reviews
1 / 20
4.0
OkayJennifer,Sep 2026
ORD - LGA
Overall
7.8
Boarding
8.1
Comfort
7.8
Crew
8.5
Entertainment
7.8
Food
7.2
Reviews
1 / 20
4.0
OkayJennifer,Sep 2026
ORD - LGA
Related info for your journey
Find useful and relevant information for your journey from Columbus to Biloxi. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.
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Complete your trip
Complete your trip to Biloxi by adding a car rental and/or hotel reservation to your travel itinerary.
Search flights from Columbus to Biloxi by cabin class
Find flights from Columbus to Biloxi, based on your preferred cabin class, be it economy, premium economy, business, or first class.
Columbus and Biloxi flights
Browse other Columbus and Biloxi flight options. Last updated on September 12, 2026.
Popular flight searches
Check out other popular destinations found by fellow travelers in 2026
Top 7 airlines flying from Columbus to Biloxi
Discover the top 7 airlines that operate flights from Columbus to Biloxi. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 7,457,451 searches. Data last updated September 12, 2026.
| Airline | Cheapest | Average | Flexibility | On-time |
|---|---|---|---|---|
| Cheapest$99 | Average$197 | FlexibilityNo cancel fee | On-timeN/A | |
| Cheapest$130 | Average$130 | FlexibilityNo cancel fee | On-time88% | |
| Cheapest$160 | Average$249 | FlexibilityNo cancel fee | On-time62% | |
| Cheapest$248 | Average$388 | FlexibilityNo cancel fee | On-time69% | |
| Cheapest$248 | Average$411 | FlexibilityNo cancel fee | On-timeN/A | |
| Cheapest$268 | Average$428 | FlexibilityNo cancel fee | On-time71% | |
| Cheapest$304 | Average$410 | FlexibilityNo cancel fee | On-time63% |