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$77+ Cheap flights from Panama City, FL to Cleveland (ECP - CLE)

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 10/29. Fares are subject to change and may not be available on all flights or dates of travel.
ECP — CLE
Oct 15 — Oct 221
Wed 10/15
Wed 10/22
1 adult, Economy
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Cheap flight deals from Panama City to Cleveland

Discover tips and strategies to find the most affordable flight options for your journey from Panama City (ECP) to Cleveland (CLE). Learn about various techniques such as flexible date searches, comparing prices across and setting up price alerts. Use these methods to find the cheapest flights available for your travel needs. Data last updated September 15, 2025.

Round-trip from

$203
(Delta)

One-way from

$77
(Southwest)

Popular in

November

Cheapest in

June

Average price

$335
From Panama City NW Florida Beaches to Cleveland Hopkins Intl
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One-way flight from Panama City NW Florida Beaches to Cleveland Hopkins Intl
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Highest demand for flights based on searches. 16% potential increase in price ($76 potential increase over avg. RT price).
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Cheapest flight prices on average. 6% potential price decrease ($24 potential savings vs. average RT price).
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Average for round-trip flights in September 2025
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Find flight deals from Panama City to Cleveland

Cheapest flights from Panama City to Cleveland
Explore the most affordable flight options available from Panama City to Cleveland. Find the lowest fares from popular airlines and budget airlines, with prices last updated on September 15, 2025.

This Delta deal was found by Cheapflights users on 9/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 11/85:00 pmECP - CLE
1 stop6h 36mDelta
Fri 11/147:46 pmCLE - ECP
1 stop4h 11mDelta
Deal found 9/12$215
This American Airlines deal was found by Cheapflights users on 9/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 11/86:47 amECP - CLE
1 stop8h 48mAmerican Airlines
Fri 11/143:24 pmCLE - ECP
2 stops8h 51mAmerican Airlines
Deal found 9/12$229
This Delta deal was found by Cheapflights users on 9/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 11/246:40 pmECP - CLE
1 stop5h 04mDelta
Tue 12/24:59 pmCLE - ECP
1 stop4h 32mDelta
Deal found 9/13$247
This American Airlines deal was found by Cheapflights users on 9/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/33:29 pmECP - CLE
1 stop7h 09mAmerican Airlines
Sun 10/56:01 amCLE - ECP
1 stop4h 41mAmerican Airlines
Deal found 9/12$251
This Delta deal was found by Cheapflights users on 9/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 11/246:00 amECP - CLE
1 stop3h 43mDelta
Thu 11/272:10 pmCLE - ECP
1 stop6h 28mDelta
Deal found 9/13$257
This American Airlines deal was found by Cheapflights users on 9/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 10/115:30 amECP - CLE
1 stop5h 16mAmerican Airlines
Sat 10/183:42 pmCLE - ECP
2 stops9h 02mAmerican Airlines
Deal found 9/13$262
This Delta deal was found by Cheapflights users on 9/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 11/255:00 pmECP - CLE
1 stop6h 44mDelta
Tue 12/26:52 pmCLE - ECP
1 stop5h 06mDelta
Deal found 9/13$297
This Delta deal was found by Cheapflights users on 9/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 11/276:00 amECP - CLE
1 stop3h 43mDelta
Thu 11/274:51 pmCLE - ECP
1 stop3h 47mDelta
Deal found 9/13$308
This Delta deal was found by Cheapflights users on 9/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 11/216:00 amECP - CLE
1 stop6h 05mDelta
Tue 12/26:52 pmCLE - ECP
1 stop5h 06mDelta
Deal found 9/13$312
This Delta deal was found by Cheapflights users on 9/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 11/246:00 amECP - CLE
1 stop3h 43mDelta
Mon 12/17:46 pmCLE - ECP
1 stop4h 11mDelta
Deal found 9/13$322

Cheapflights Fare Finder

 
Customize your flight search to find flights from Panama City to Cleveland that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated September 15, 2025.
Use the filters below to find and compare flights from Panama City to Cleveland that are best for you.

Fly from

Panama City

Fly to

Cleveland

Route

Depart

Return

Price

Panama CityCleveland

ECP - CLE

ECPCLE

Panama City NW Florida Beaches

Sat 11/8

5:00 pm-12:36 am

1 stop6h 36m

Cleveland Hopkins Intl

Fri 11/14

7:46 pm-10:57 pm

1 stop4h 11m

$215

Panama CityCleveland

ECP - CLE

ECPCLE

Panama City NW Florida Beaches

Thu 11/27

5:09 pm-12:44 am

1 stop6h 35m

Cleveland Hopkins Intl

Tue 12/2

4:59 pm-8:31 pm

1 stop4h 32m

$247

Panama CityCleveland

ECP - CLE

ECPCLE

Panama City NW Florida Beaches

Mon 11/24

6:40 pm-12:44 am

1 stop5h 04m

Cleveland Hopkins Intl

Tue 12/2

4:59 pm-8:31 pm

1 stop4h 32m

$247

Panama CityCleveland

ECP - CLE

ECPCLE

Panama City NW Florida Beaches

Fri 10/3

3:29 pm-11:38 pm

1 stop7h 09m

Cleveland Hopkins Intl

Sun 10/5

6:01 am-9:42 am

1 stop4h 41m

$251

Panama CityCleveland

ECP - CLE

ECPCLE

Panama City NW Florida Beaches

Mon 11/24

6:00 am-10:43 am

1 stop3h 43m

Cleveland Hopkins Intl

Thu 11/27

2:10 pm-7:38 pm

1 stop6h 28m

$257

Panama CityCleveland

ECP - CLE

ECPCLE

Panama City NW Florida Beaches

Wed 11/26

5:00 pm-12:44 am

1 stop6h 44m

Cleveland Hopkins Intl

Tue 12/2

4:59 pm-8:31 pm

1 stop4h 32m

$297

Panama CityCleveland

ECP - CLE

ECPCLE

Panama City NW Florida Beaches

Sat 10/11

5:30 am-11:46 am

1 stop5h 16m

Cleveland Hopkins Intl

Sat 10/18

12:05 pm-7:32 pm

1 stop8h 27m

$307

Panama CityCleveland

ECP - CLE

ECPCLE

Panama City NW Florida Beaches

Thu 11/27

6:00 am-10:43 am

1 stop3h 43m

Cleveland Hopkins Intl

Fri 11/28

7:05 am-12:47 pm

1 stop6h 42m

$308

Panama CityCleveland

ECP - CLE

ECPCLE

Panama City NW Florida Beaches

Sun 11/23

6:00 am-1:05 pm

1 stop6h 05m

Cleveland Hopkins Intl

Tue 12/2

4:59 pm-10:58 pm

1 stop6h 59m

$312

Panama CityCleveland

ECP - CLE

ECPCLE

Panama City NW Florida Beaches

Sat 11/22

11:11 am-5:44 pm

1 stop5h 33m

Cleveland Hopkins Intl

Tue 12/2

4:59 pm-10:58 pm

1 stop6h 59m

$312

Flights are sorted by cheapest round-trip flights first.

Deals found on 9/12

Showing 1-10 of 21 results
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Best time to book a flight from Panama City to Cleveland

Have a flexible travel schedule? Discover the best time to fly to Cleveland from Panama City with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Panama City to Cleveland

What is the cheapest month to book a flight from Panama City, Florida to Cleveland?

Currently, April is the cheapest month in which you can book a flight from Panama City, Florida to Cleveland (average of $250). Flying from Panama City, Florida to Cleveland in June is currently the most expensive (average of $290). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

What is the cheapest time of day to fly from ECP to CLE?

Find hourly flight availability from Panama City to Cleveland. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated September 15, 2025.

One of the essential ways to save on airfare from Panama City, Florida to Cleveland is to remain as flexible as possible. Flights that are in the afternoon tend to be the most expensive. A flight in the evening could potentially save you up to 18% on airfare.

Reviews of airlines servicing Cleveland

Get insights into the airlines that provide service to Cleveland. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Cleveland. Reviews last updated September 15, 2025.
See what other customers who have flown with Southwest, Delta, and American Airlines from Panama City to Cleveland have to say. You can also see how each airline compares in terms of entertainment options, comfort, food, crew/service, and boarding process.
Southwest
8.0
Very good
4,245 reviews

Crew

8.6

Comfort

8.0

Food

7.0

Entertainment

7.5

Overall

8.0

Boarding

8.1

Reviews

1 / 20
2.0
Mediocre

Mike,Aug 2025

OKC - AUS

AC was not adequate, even on a night flight. WiFi subpar even for the airlines
Southwest
8.0
Very good
4,245 reviews
Southwest
8.0
Very good
4,245 reviews

Crew

8.6

Comfort

8.0

Food

7.0

Entertainment

7.5

Overall

8.0

Boarding

8.1

Reviews

1 / 20
2.0
Mediocre

Mike,Aug 2025

OKC - AUS

AC was not adequate, even on a night flight. WiFi subpar even for the airlines
Delta
8.0
Very good
7,956 reviews
Southwest
8.0
Very good
4,245 reviews

Crew

8.6

Comfort

8.0

Food

7.0

Entertainment

7.5

Overall

8.0

Boarding

8.1

Reviews

1 / 20
2.0
Mediocre

Mike,Aug 2025

OKC - AUS

AC was not adequate, even on a night flight. WiFi subpar even for the airlines
American Airlines
7.2
Good
10,000 reviews
Southwest
8.0
Very good
4,245 reviews

Crew

8.6

Comfort

8.0

Food

7.0

Entertainment

7.5

Overall

8.0

Boarding

8.1

Reviews

1 / 20
2.0
Mediocre

Mike,Aug 2025

OKC - AUS

AC was not adequate, even on a night flight. WiFi subpar even for the airlines

Related info for your journey

Find useful and relevant information for your journey from Panama City to Cleveland. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • How long is the flight from Panama City, Florida to Cleveland?

    A quick flight from Panama City, Florida to Cleveland can take about 6h 36m. Delta provides one of the quickest options available for as low as $215. The distance between Panama City, Florida and Cleveland is about 794 mi. This flight may include one or multiple stops.

  • What are the cheapest airlines flying from Panama City, Florida to Cleveland round-trip?

    Currently priced at $237, Delta will fly you from Panama City, Florida to Cleveland and back. In addition to Delta, many other airlines offer competitively priced options for your trip. Search Cheapflights for deals from American Airlines and Southwest - these airlines can fly you to your destination from $256 and $292, respectively. You may be able to fly from Panama City, Florida to Cleveland for 38% less than the average price by searching for these airlines.

  • What are the cheapest airlines to fly from Panama City, Florida to Cleveland one-way?

    To fly one-way, consider booking your trip with Southwest, which is currently one of the cheapest options available, starting at $77. American Airlines flights start at $96 while deals on Delta start at $119 one-way.

  • Can I find deals for flights from Panama City to Cleveland that include hotel bookings?

    Yes. In addition to deals on Panama City to Cleveland flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Panama City to Cleveland?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Panama City to Cleveland.

  • Can I find deals for business class flights from Panama City to Cleveland?

    Yes. Cheapflights offers flight deals from Panama City to Cleveland by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Panama City, Florida to Cleveland?

    Currently, April is the cheapest month in which you can book a flight from Panama City, Florida to Cleveland (average of $250). Flying from Panama City, Florida to Cleveland in June is currently the most expensive (average of $290). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

Traveling to a place near Cleveland?

Book flights to Cleveland if you plan to visit one of these locations
Sandusky
Mentor
Beachwood
Wooster
Avon
Mansfield
Independence
Willoughby
Elyria
Streetsboro
Cleveland Heights
North Olmsted
Cuyahoga Falls
Macedonia
Strongsville
Kent
Medina
Westlake

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Top 3 airlines flying from Panama City to Cleveland

Discover the top 3 airlines that operate flights from Panama City to Cleveland. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated September 15, 2025.
AirlineCheapestAverageFlexibilityOn-time
DeltaCheapest$237Average$366FlexibilityNo cancel feeOn-timeN/A
American AirlinesCheapest$256Average$361FlexibilityNo cancel feeOn-time71%
SouthwestCheapest$292Average$334FlexibilityNo cancel feeOn-time63%

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