$133+ Cheap flights from Biloxi, MS to Chicago (CHI)
This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 2/23. Fares are subject to change and may not be available on all flights or dates of travel.
MSY — CHI
Mar 5 — Mar 121
1 adult, Economy
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1. Tell us where you want to go
Enter your travel information like dates, passengers, trip type (one-way or round trip), and preferred cabin class then click “Find deals”2. Select your favorite providers
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Cheapest flights from Biloxi to ChicagoExplore the most affordable flight options available from Biloxi to Chicago. Find the lowest fares from popular airlines and budget airlines, with prices last updated on February 3, 2026.
Explore the most affordable flight options available from Biloxi to Chicago. Find the lowest fares from popular airlines and budget airlines, with prices last updated on February 3, 2026.
This Kiwi.com deal was found by Cheapflights users on 2/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 8/277:50 pm
GPT
- ORD
1 stop12h 09m
Multiple Airlines
Sun 8/3010:17 am
ORD
- GPT
1 stop21h 24m
Multiple Airlines
Deal found 2/2![Multiple Airlines logo]()
$259
This Delta deal was found by Cheapflights users on 1/31. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 8/276:00 pm
GPT
- ORD
1 stop5h 57m
Delta
Sun 8/307:10 am
ORD
- GPT
1 stop6h 23m
Delta
Deal found 1/31![Delta logo]()
$269
This Kiwi.com deal was found by Cheapflights users on 2/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 5/37:20 pm
GPT
- ORD
1 stop12h 39m
Multiple Airlines
Sat 5/91:27 pm
ORD
- GPT
2 stops29h 43m
Multiple Airlines
Deal found 2/2![Multiple Airlines logo]()
$277
This American Airlines deal was found by Cheapflights users on 1/31. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 2/144:29 pm
GPT
- ORD
1 stop7h 29m
American Airlines
Mon 2/168:10 am
ORD
- GPT
1 stop7h 49m
American Airlines
Deal found 1/31![American Airlines logo]()
$279
This Delta deal was found by Cheapflights users on 2/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 2/276:00 pm
GPT
- MDW
1 stop4h 31m
Delta
Mon 3/210:49 am
MDW
- GPT
1 stop6h 26m
Delta
Deal found 2/1![Delta logo]()
$294
This Delta deal was found by Cheapflights users on 2/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 3/235:57 pm
GPT
- ORD
1 stop5h 57m
Delta
Mon 3/305:59 pm
ORD
- GPT
1 stop4h 16m
Delta
Deal found 2/1![Delta logo]()
$294
This Delta deal was found by Cheapflights users on 2/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 2/2810:25 am
GPT
- MDW
1 stop4h 56m
Delta
Mon 3/210:49 am
MDW
- GPT
1 stop6h 26m
Delta
Deal found 2/1![Delta logo]()
$304
This Kiwi.com deal was found by Cheapflights users on 2/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 3/236:54 pm
GPT
- ORD
1 stop19h 04m
Multiple Airlines
Wed 3/254:18 pm
ORD
- GPT
1 stop26h 22m
Multiple Airlines
Deal found 2/1![Multiple Airlines logo]()
$321
This Delta deal was found by Cheapflights users on 2/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 3/199:48 am
GPT
- ORD
1 stop7h 01m
Delta
Mon 3/305:59 pm
ORD
- GPT
1 stop4h 16m
Delta
Deal found 2/2![Delta logo]()
$354
This American Airlines deal was found by Cheapflights users on 2/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 8/276:30 pm
GPT
- ORD
1 stop5h 18m
American Airlines
Sun 8/305:20 am
ORD
- GPT
1 stop6h 53m
American Airlines
Deal found 2/2![American Airlines logo]()
$359
This Kiwi.com deal was found by Cheapflights users on 2/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 5/317:50 pm
GPT
- ORD
1 stop12h 09m
Multiple Airlines
Sat 6/277:59 pm
ORD
- GPT
2 stops35h 42m
Multiple Airlines
Deal found 2/2![Multiple Airlines logo]()
$372
This Delta deal was found by Cheapflights users on 2/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 8/276:00 am
GPT
- MDW
1 stop5h 54m
Delta
Sun 8/301:05 pm
MDW
- GPT
1 stop4h 12m
Delta
Deal found 2/2![Delta logo]()
$483
Best flights from Biloxi to ChicagoDiscover carefully curated flight deals from Biloxi to Chicago that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated February 3, 2026.
Discover carefully curated flight deals from Biloxi to Chicago that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated February 3, 2026.
This Delta deal was found by Cheapflights users on 2/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 2/283:00 pm
GPT
- ORD
1 stop4h 19m
Delta
Mon 3/29:48 am
ORD
- GPT
1 stop4h 18m
Delta
Deal found 2/1![Delta logo]()
$269
This Kiwi.com deal was found by Cheapflights users on 2/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 5/37:20 pm
GPT
- ORD
1 stop12h 39m
Multiple Airlines
Sat 5/91:27 pm
ORD
- GPT
2 stops29h 43m
Multiple Airlines
Deal found 2/2![Multiple Airlines logo]()
$277
This American Airlines deal was found by Cheapflights users on 1/31. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 2/144:29 pm
GPT
- ORD
1 stop7h 29m
American Airlines
Mon 2/168:10 am
ORD
- GPT
1 stop7h 49m
American Airlines
Deal found 1/31![American Airlines logo]()
$279
This United Airlines deal was found by Cheapflights users on 2/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 3/244:55 pm
GPT
- ORD
1 stop7h 04m
United Airlines
Mon 3/307:15 am
ORD
- GPT
2 stops12h 38m
United Airlines
Deal found 2/1![United Airlines logo]()
$501
This Delta deal was found by Cheapflights users on 2/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 2/276:00 pm
GPT
- MDW
1 stop4h 31m
Delta
Mon 3/210:49 am
MDW
- GPT
1 stop6h 26m
Delta
Deal found 2/1![Delta logo]()
$294
This Kiwi.com deal was found by Cheapflights users on 2/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 3/236:54 pm
GPT
- ORD
1 stop19h 04m
Multiple Airlines
Wed 3/254:18 pm
ORD
- GPT
1 stop26h 22m
Multiple Airlines
Deal found 2/1![Multiple Airlines logo]()
$321
This Delta deal was found by Cheapflights users on 2/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 3/235:57 pm
GPT
- ORD
1 stop5h 57m
Delta
Mon 3/305:59 pm
ORD
- GPT
1 stop4h 16m
Delta
Deal found 2/1![Delta logo]()
$294
This Delta deal was found by Cheapflights users on 2/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 3/199:48 am
GPT
- ORD
1 stop7h 01m
Delta
Mon 3/305:59 pm
ORD
- GPT
1 stop4h 16m
Delta
Deal found 2/2![Delta logo]()
$354
This Kiwi.com deal was found by Cheapflights users on 2/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 6/117:50 pm
GPT
- ORD
1 stop12h 09m
Multiple Airlines
Sun 6/148:53 pm
ORD
- GPT
1 stop19h 58m
Multiple Airlines
Deal found 2/2![Multiple Airlines logo]()
$413
This American Airlines deal was found by Cheapflights users on 2/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 2/186:31 am
GPT
- ORD
1 stop7h 45m
American Airlines
Sun 2/225:00 am
ORD
- GPT
1 stop5h 13m
American Airlines
Deal found 2/3![American Airlines logo]()
$506
This Kiwi.com deal was found by Cheapflights users on 2/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 6/187:50 pm
GPT
- ORD
1 stop12h 09m
Multiple Airlines
Sun 6/2112:41 pm
ORD
- GPT
1 stop6h 29m
Multiple Airlines
Deal found 2/1![Multiple Airlines logo]()
$481
This Delta deal was found by Cheapflights users on 2/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 2/176:00 am
GPT
- MDW
1 stop5h 59m
Delta
Sat 2/214:13 pm
MDW
- GPT
1 stop5h 41m
Delta
Deal found 2/1![Delta logo]()
$620
This Delta deal was found by Cheapflights users on 2/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 3/235:57 pm
GPT
- MDW
1 stop4h 34m
Delta
Wed 3/2510:45 am
MDW
- GPT
1 stop6h 26m
Delta
Deal found 2/1![Delta logo]()
$779
This Delta deal was found by Cheapflights users on 2/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 3/195:57 pm
GPT
- MDW
1 stop4h 34m
Delta
Sat 3/214:30 pm
MDW
- GPT
1 stop5h 45m
Delta
Deal found 2/1![Delta logo]()
$804
This Delta deal was found by Cheapflights users on 2/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 7/183:00 pm
GPT
- MDW
1 stop6h 45m
Delta
Sun 7/191:05 pm
MDW
- GPT
1 stop4h 12m
Delta
Deal found 2/1![Delta logo]()
$814
This Delta deal was found by Cheapflights users on 2/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 6/186:00 am
GPT
- MDW
1 stop5h 56m
Delta
Sun 6/2110:35 am
MDW
- GPT
1 stop6h 42m
Delta
Deal found 2/1![Delta logo]()
$864
This Delta deal was found by Cheapflights users on 2/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 3/195:57 pm
GPT
- MDW
1 stop4h 34m
Delta
Sun 3/2210:45 am
MDW
- GPT
1 stop6h 26m
Delta
Deal found 2/1![Delta logo]()
$934
This Delta deal was found by Cheapflights users on 2/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 2/2810:25 am
GPT
- MDW
1 stop4h 56m
Delta
Mon 3/29:34 am
MDW
- GPT
2 stops7h 41m
Delta
Deal found 2/1![Delta logo]()
$980
This Delta deal was found by Cheapflights users on 2/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 2/186:00 am
GPT
- MDW
1 stop5h 59m
Delta
Sun 2/2212:45 pm
MDW
- GPT
1 stop4h 30m
Delta
Deal found 2/3![Delta logo]()
$1,089
Last-minute flights from Biloxi to ChicagoDiscover last-minute flight deals from Biloxi to Chicago. Data last updated February 3, 2026 and is based on user searches.
Discover last-minute flight deals from Biloxi to Chicago. Data last updated February 3, 2026 and is based on user searches.
This American Airlines deal was found by Cheapflights users on 1/31. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 2/144:29 pm
GPT
- ORD
1 stop7h 29m
American Airlines
Mon 2/168:10 am
ORD
- GPT
1 stop7h 49m
American Airlines
Deal found 1/31![American Airlines logo]()
$279
This Delta deal was found by Cheapflights users on 2/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 2/1710:11 am
GPT
- ORD
1 stop6h 38m
Delta
Sat 2/215:25 am
ORD
- GPT
1 stop4h 15m
Delta
Deal found 2/1![Delta logo]()
$410
This American Airlines deal was found by Cheapflights users on 2/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 2/186:31 am
GPT
- ORD
1 stop7h 45m
American Airlines
Sun 2/225:00 am
ORD
- GPT
1 stop5h 13m
American Airlines
Deal found 2/3![American Airlines logo]()
$506
This Delta deal was found by Cheapflights users on 2/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 2/276:00 pm
GPT
- ORD
1 stop5h 56m
Delta
Mon 3/29:48 am
ORD
- GPT
1 stop7h 27m
Delta
Deal found 2/1![Delta logo]()
$269
This Delta deal was found by Cheapflights users on 2/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 2/276:00 pm
GPT
- MDW
1 stop4h 31m
Delta
Mon 3/210:49 am
MDW
- GPT
1 stop6h 26m
Delta
Deal found 2/1![Delta logo]()
$294
This Kiwi.com deal was found by Cheapflights users on 2/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 2/276:54 pm
GPT
- ORD
1 stop22h 09m
Multiple Airlines
Mon 3/26:00 am
ORD
- GPT
2 stops12h 14m
Multiple Airlines
Deal found 2/1![Multiple Airlines logo]()
$446
This Delta deal was found by Cheapflights users on 2/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 2/2810:25 am
GPT
- MDW
1 stop4h 56m
Delta
Mon 3/210:49 am
MDW
- GPT
1 stop6h 26m
Delta
Deal found 2/1![Delta logo]()
$304
This Delta deal was found by Cheapflights users on 2/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 3/199:48 am
GPT
- ORD
1 stop7h 01m
Delta
Mon 3/305:59 pm
ORD
- GPT
1 stop4h 16m
Delta
Deal found 2/2![Delta logo]()
$354
This United Airlines deal was found by Cheapflights users on 2/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 3/194:55 pm
GPT
- ORD
1 stop7h 04m
United Airlines
Sat 3/219:15 pm
ORD
- GPT
1 stop22h 30m
United Airlines
Deal found 2/1![United Airlines logo]()
$469
This Delta deal was found by Cheapflights users on 2/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 3/235:57 pm
GPT
- ORD
1 stop5h 57m
Delta
Mon 3/305:59 pm
ORD
- GPT
1 stop4h 16m
Delta
Deal found 2/1![Delta logo]()
$294
This Kiwi.com deal was found by Cheapflights users on 2/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 3/236:54 pm
GPT
- ORD
1 stop19h 04m
Multiple Airlines
Wed 3/254:18 pm
ORD
- GPT
1 stop26h 22m
Multiple Airlines
Deal found 2/1![Multiple Airlines logo]()
$321
This United Airlines deal was found by Cheapflights users on 2/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 3/244:55 pm
GPT
- ORD
1 stop7h 04m
United Airlines
Mon 3/307:15 am
ORD
- GPT
2 stops12h 38m
United Airlines
Deal found 2/1![United Airlines logo]()
$501
One-way flights from Biloxi to ChicagoSearch for one-way flight options from Biloxi to Chicago. Find affordable one-way fares based on user searches. Data last updated February 3, 2026.
Search for one-way flight options from Biloxi to Chicago. Find affordable one-way fares based on user searches. Data last updated February 3, 2026.
This Kiwi.com deal was found by Cheapflights users on 2/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 2/236:54 pm
GPT
- ORD
2 stops15h 57m
Multiple Airlines
Deal found 2/2![Multiple Airlines logo]()
$133
This Kiwi.com deal was found by Cheapflights users on 2/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 2/236:54 pm
GPT
- MDW
2 stops24h 13m
Multiple Airlines
Deal found 2/2![Multiple Airlines logo]()
$136
This Delta deal was found by Cheapflights users on 2/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 4/19:48 am
GPT
- ORD
1 stop7h 01m
Delta
Deal found 2/1![Delta logo]()
$199
This Delta deal was found by Cheapflights users on 2/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 2/236:00 pm
GPT
- MDW
1 stop4h 31m
Delta
Deal found 2/2![Delta logo]()
$245
This United Airlines deal was found by Cheapflights users on 2/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 4/12:05 pm
GPT
- ORD
2 stops19h 12m
United Airlines
Deal found 2/1![United Airlines logo]()
$321
This Delta deal was found by Cheapflights users on 2/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 4/16:00 am
GPT
- MDW
2 stops6h 29m
Delta
Deal found 2/1![Delta logo]()
$948
Find flight deals from Biloxi to Chicago
Keep the following information in mind while searching for Biloxi to Chicago flight deals. Data was last updated February 3, 2026.
Most accurate provider | FlightHub 3 stars |
|---|---|
Most trusted provider | FlightHub 3 stars |
Round-trip from | $269 (Delta) |
One-way from | $133 (Kiwi.com) |
Popular in | February |
Cheapest in | November |
Average price | $669 |
Cheapflights Fare Finder
Customize your flight search to find flights from Biloxi to Chicago that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated February 3, 2026.
Use the filters below to find and compare flights from Biloxi to Chicago that are best for you.
Fly from
Biloxi
Fly to
Chicago
Route
Depart
Return
Price
GulfportChicago
GPT - ORD
GPTORD
Gulfport Biloxi Regional
Sat 2/28
3:00 pm-7:19 pm
1 stop4h 19m
Chicago O'Hare Intl
Mon 3/2
9:48 am-2:06 pm
1 stop4h 18m
$269
GulfportChicago
GPT - ORD
GPTORD
Gulfport Biloxi Regional
Sun 5/3
7:20 pm-7:59 am
1 stop12h 39m
Chicago O'Hare Intl
Sat 5/9
1:27 pm-7:10 pm
2 stops29h 43m
$277
GulfportChicago
GPT - ORD
GPTORD
Gulfport Biloxi Regional
Sat 2/14
4:29 pm-11:58 pm
1 stop7h 29m
Chicago O'Hare Intl
Mon 2/16
8:10 am-3:59 pm
1 stop7h 49m
$279
GulfportChicago
GPT - MDW
GPTMDW
Gulfport Biloxi Regional
Fri 2/27
6:00 pm-10:31 pm
1 stop4h 31m
Chicago Midway
Mon 3/2
10:49 am-5:15 pm
1 stop6h 26m
$294
GulfportChicago
GPT - ORD
GPTORD
Gulfport Biloxi Regional
Mon 3/23
5:57 pm-11:54 pm
1 stop5h 57m
Chicago O'Hare Intl
Mon 3/30
5:59 pm-10:15 pm
1 stop4h 16m
$294
GulfportChicago
GPT - ORD
GPTORD
Gulfport Biloxi Regional
Mon 3/23
6:54 pm-1:58 pm
1 stop19h 04m
Chicago O'Hare Intl
Wed 3/25
4:18 pm-6:40 pm
1 stop26h 22m
$321
GulfportChicago
GPT - ORD
GPTORD
Gulfport Biloxi Regional
Thu 3/19
9:48 am-4:49 pm
1 stop7h 01m
Chicago O'Hare Intl
Mon 3/30
5:59 pm-10:15 pm
1 stop4h 16m
$354
GulfportChicago
GPT - ORD
GPTORD
Gulfport Biloxi Regional
Thu 6/11
7:50 pm-7:59 am
1 stop12h 09m
Chicago O'Hare Intl
Sun 6/14
8:53 pm-4:51 pm
1 stop19h 58m
$413
GulfportChicago
GPT - ORD
GPTORD
Gulfport Biloxi Regional
Thu 6/18
7:50 pm-7:59 am
1 stop12h 09m
Chicago O'Hare Intl
Sun 6/21
12:41 pm-7:10 pm
1 stop6h 29m
$481
GulfportChicago
GPT - ORD
GPTORD
Gulfport Biloxi Regional
Tue 3/24
4:55 pm-11:59 pm
1 stop7h 04m
Chicago O'Hare Intl
Mon 3/30
7:15 am-7:53 pm
2 stops12h 38m
$501
Showing 1-10 of 25 results
Best time to book a flight from Biloxi to Chicago
Have a flexible travel schedule? Discover the best time to fly to Chicago from Biloxi with our price prediction graph.
GPT-ORD
GPT-MDW
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.
Cheapflights Insights
Everything you need to know about your flight from Biloxi to Chicago
B1L-CHI
GPT-ORD
GPT-MDW
What is the cheapest month to book a flight from Biloxi to Chicago?
Currently, February is the cheapest month in which you can book a flight from Biloxi to Chicago (average of $54). Flying from Biloxi to Chicago in December is currently the most expensive (average of $159). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.
What is the cheapest time of day to fly from B1L to CHI?
Find hourly flight availability from Biloxi to Chicago. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated February 3, 2026.
It’s typically best to fly out from Biloxi to Chicago in the evening. Doing so could potentially save you 62% on the flight price compared to flying at noon, which is usually more expensive.
What is the cheapest day to fly from Biloxi to Chicago?
Use this chart to determine the cheapest time to fly round-trip from Biloxi to Chicago. Price data was last updated on January 31, 2026.
Travelers seeking maximum savings on their Biloxi to Chicago flight should consider departing on Wednesday evenings when fares are most often at their lowest. Sunday at noon flights should be avoided if possible as fares are typically the most expensive at this time.
Weekly flight availability from Biloxi to Chicago
Explore weekly flight availability from Biloxi to Chicago. Discover flights operating on different days of the week, giving you the flexibility to choose a travel day that best fits your plans. Compare info to find the most convenient option for your journey. Data last updated February 3, 2026.
The most flights from B1L to CHI are scheduled on a Monday (38 on average). You will have fewer flight options on Tuesday, which is when the least amount of flights are scheduled (18 on average).
Reviews of airlines servicing Chicago
Get insights into the airlines that provide service to Chicago. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Chicago. Reviews last updated February 3, 2026.
Read through reviews of airlines operating flights from Biloxi to Chicago, such as Delta and American Airlines. You can also see how each airline stacks up in terms of entertainment options, comfort, food, crew/service, and boarding process.
Crew
8.5
Comfort
7.9
Overall
7.9
Entertainment
7.8
Boarding
8.1
Food
7.2
Reviews
1 / 20
6.0
GoodJim,Nov 2025
AVL - ATL
Crew
8.5
Comfort
7.9
Overall
7.9
Entertainment
7.8
Boarding
8.1
Food
7.2
Reviews
1 / 20
6.0
GoodJim,Nov 2025
AVL - ATL
Crew
8.5
Comfort
7.9
Overall
7.9
Entertainment
7.8
Boarding
8.1
Food
7.2
Reviews
1 / 20
6.0
GoodJim,Nov 2025
AVL - ATL
Related info for your journey
Find useful and relevant information for your journey from Biloxi to Chicago. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.
Traveling to a place near Chicago?
Book flights to Chicago if you plan to visit one of these locationsLansing
Merrillville
Hammond
Porter
Benton Harbor
Browse thousands of different options on Cheapflights for your next trip
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Alternative routes for Biloxi to Chicago
See prices for flight routes from nearby airports that may be better suited for you.
Top 5 airlines flying from Biloxi to Chicago
Discover the top 5 airlines that operate flights from Biloxi to Chicago. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated February 3, 2026.
| Airline | Cheapest | Average | Flexibility | On-time |
|---|---|---|---|---|
| Cheapest$60 | Average$136 | FlexibilityNo cancel fee | On-time65% | |
| Cheapest$133 | Average$273 | FlexibilityNo cancel fee | On-time69% | |
| Cheapest$159 | Average$357 | FlexibilityNo cancel fee | On-time71% | |
| Cheapest$173 | Average$267 | FlexibilityNo cancel fee | On-time63% | |
| Cheapest$210 | Average$448 | FlexibilityNo cancel fee | On-timeN/A |