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$226+ Cheap flights from Biloxi, MS to Chicago (CHI)

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 10/15. Fares are subject to change and may not be available on all flights or dates of travel.
MSY — CHI
oct. 15 — oct. 221
mié. 10/15
mié. 10/22
1 adult, Economy
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Cheap flight deals from Biloxi to Chicago

Keep the following information in mind while searching for Biloxi to Chicago flight deals. Data was last updated septiembre 15, 2025.

Round-trip from

$228
(Kiwi.com)

One-way from

$226
(Delta)

Popular in

February

Cheapest in

April

Average price

$648
From Biloxi to Chicago (CHI)
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One-way flight from Biloxi to Chicago (CHI)
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Highest demand for flights based on searches. 11% potential increase in price ($59 potential increase over avg. RT price).
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Cheapest flight prices on average. 5% potential price decrease ($22 potential savings vs. average RT price).
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Average for round-trip flights in September 2025
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Find flight deals from Biloxi to Chicago

Cheapest flights from Biloxi to Chicago
Explore the most affordable flight options available from Biloxi to Chicago. Find the lowest fares from popular airlines and budget airlines, with prices last updated on septiembre 15, 2025.

This Kiwi.com deal was found by Cheapflights users on 9/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
jue. 11/137:55 pmGPT - MDW
1 stop26h 15mMultiple Airlines
dom. 11/166:06 pmMDW - GPT
1 stop14h 53mMultiple Airlines
Deal found 9/15$228
This Kiwi.com deal was found by Cheapflights users on 9/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
vie. 10/36:51 pmGPT - ORD
1 stop15h 26mMultiple Airlines
dom. 10/58:05 amORD - GPT
1 stop24h 54mMultiple Airlines
Deal found 9/14$228
This Kiwi.com deal was found by Cheapflights users on 9/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
lun. 10/136:51 pmGPT - ORD
1 stop15h 17mMultiple Airlines
mié. 10/156:58 pmORD - GPT
1 stop24h 17mMultiple Airlines
Deal found 9/13$236
This Delta deal was found by Cheapflights users on 9/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
sáb. 11/153:30 pmGPT - ORD
1 stop6h 23mDelta
mar. 11/181:09 pmORD - GPT
1 stop4h 04mDelta
Deal found 9/13$249
This Kiwi.com deal was found by Cheapflights users on 9/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
jue. 11/137:55 pmGPT - ORD
2 stops17h 21mMultiple Airlines
dom. 11/167:05 amORD - GPT
1 stop25h 54mMultiple Airlines
Deal found 9/15$254
This United Airlines deal was found by Cheapflights users on 9/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
mar. 9/305:25 pmGPT - ORD
1 stop6h 49mUnited Airlines
sáb. 10/47:10 amORD - GPT
1 stop6h 15mUnited Airlines
Deal found 9/15$259
This Kiwi.com deal was found by Cheapflights users on 9/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
vie. 10/176:51 pmGPT - ORD
2 stops25h 57mMultiple Airlines
dom. 10/196:00 amORD - GPT
1 stop13h 15mMultiple Airlines
Deal found 9/14$268
This Delta deal was found by Cheapflights users on 9/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
mié. 12/246:00 amGPT - ORD
1 stop6h 05mDelta
sáb. 12/275:40 amORD - GPT
1 stop4h 51mDelta
Deal found 9/15$279
This Delta deal was found by Cheapflights users on 9/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
vie. 9/266:04 pmGPT - ORD
1 stop5h 50mDelta
mar. 9/307:20 amORD - GPT
1 stop6h 00mDelta
Deal found 9/15$284
This Kiwi.com deal was found by Cheapflights users on 9/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
vie. 10/176:51 pmGPT - MDW
2 stops27h 56mMultiple Airlines
dom. 10/1912:09 pmMDW - GPT
1 stop7h 06mMultiple Airlines
Deal found 9/14$305
This Kiwi.com deal was found by Cheapflights users on 9/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
vie. 10/36:51 pmGPT - MDW
2 stops28h 50mMultiple Airlines
dom. 10/510:13 amMDW - GPT
1 stop9h 02mMultiple Airlines
Deal found 9/14$306
This Delta deal was found by Cheapflights users on 9/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
sáb. 12/136:00 amGPT - MDW
2 stops12h 18mDelta
mar. 12/1610:49 amMDW - GPT
1 stop6h 25mDelta
Deal found 9/13$332

Cheapflights Fare Finder

 
Customize your flight search to find flights from Biloxi to Chicago that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated septiembre 15, 2025.
Use the filters below to find and compare flights from Biloxi to Chicago that are best for you.

Fly from

Biloxi

Fly to

Chicago

Route

Depart

Return

Price

GulfportChicago

GPT - MDW

GPTMDW

Gulfport Biloxi Regional

jue. 11/13

7:55 pm-10:10 pm

1 stop26h 15m

Chicago Midway

dom. 11/16

6:06 pm-8:59 am

1 stop14h 53m

$228

GulfportChicago

GPT - ORD

GPTORD

Gulfport Biloxi Regional

jue. 11/13

7:55 pm-5:04 pm

1 stop21h 09m

Chicago O'Hare Intl

dom. 11/16

7:05 am-8:59 am

1 stop25h 54m

$228

GulfportChicago

GPT - ORD

GPTORD

Gulfport Biloxi Regional

vie. 10/3

6:51 pm-10:17 am

1 stop15h 26m

Chicago O'Hare Intl

dom. 10/5

8:05 am-8:59 am

1 stop24h 54m

$228

GulfportChicago

GPT - ORD

GPTORD

Gulfport Biloxi Regional

lun. 10/13

6:51 pm-10:08 am

1 stop15h 17m

Chicago O'Hare Intl

mié. 10/15

6:58 pm-7:15 pm

1 stop24h 17m

$236

GulfportChicago

GPT - ORD

GPTORD

Gulfport Biloxi Regional

sáb. 11/15

3:30 pm-9:53 pm

1 stop6h 23m

Chicago O'Hare Intl

mar. 11/18

1:09 pm-5:13 pm

1 stop4h 04m

$249

GulfportChicago

GPT - ORD

GPTORD

Gulfport Biloxi Regional

vie. 2/20

6:52 pm-11:54 pm

1 stop5h 02m

Chicago O'Hare Intl

sáb. 2/21

12:05 pm-5:33 pm

1 stop5h 28m

$249

GulfportChicago

GPT - ORD

GPTORD

Gulfport Biloxi Regional

mar. 9/30

5:25 pm-12:14 am

1 stop6h 49m

Chicago O'Hare Intl

sáb. 10/4

7:10 am-1:25 pm

1 stop6h 15m

$259

GulfportChicago

GPT - ORD

GPTORD

Gulfport Biloxi Regional

vie. 10/17

6:51 pm-8:48 pm

2 stops25h 57m

Chicago O'Hare Intl

dom. 10/19

6:00 am-7:15 pm

1 stop13h 15m

$268

GulfportChicago

GPT - ORD

GPTORD

Gulfport Biloxi Regional

mié. 12/24

6:00 am-12:05 pm

1 stop6h 05m

Chicago O'Hare Intl

sáb. 12/27

5:40 am-10:31 am

1 stop4h 51m

$279

GulfportChicago

GPT - ORD

GPTORD

Gulfport Biloxi Regional

vie. 9/26

6:04 pm-11:54 pm

1 stop5h 50m

Chicago O'Hare Intl

mar. 9/30

7:20 am-1:20 pm

1 stop6h 00m

$284

Flights are sorted by cheapest round-trip flights first.

Deals found on 9/14

Showing 1-10 of 17 results
1
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Best time to book a flight from Biloxi to Chicago

Have a flexible travel schedule? Discover the best time to fly to Chicago from Biloxi with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Biloxi to Chicago

What is the cheapest month to book a flight from Biloxi to Chicago?

Currently, August is the cheapest month in which you can book a flight from Biloxi to Chicago (average of $245). Flying from Biloxi to Chicago in March is currently the most expensive (average of $321). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

What is the cheapest time of day to fly from B1L to CHI?

Find hourly flight availability from Biloxi to Chicago. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated septiembre 15, 2025.

When flying from Biloxi to Chicago, the time of day you decide to fly out makes little to no difference towards the overall price you’ll pay on tickets.

What is the cheapest day to fly from Biloxi to Chicago?

Use this chart to determine the cheapest time to fly round-trip from Biloxi to Chicago. Price data was last updated on November 3, 2024.

Travelers seeking maximum savings on their Biloxi to Chicago flight should consider departing on Tuesday mornings when fares are most often at their lowest. Friday mornings flights should be avoided if possible as fares are typically the most expensive at this time.

Weekly flight availability from Biloxi to Chicago

Explore weekly flight availability from Biloxi to Chicago. Discover flights operating on different days of the week, giving you the flexibility to choose a travel day that best fits your plans. Compare info to find the most convenient option for your journey. Data last updated septiembre 15, 2025.

The most flights from B1L to CHI are scheduled on a Sunday (33 on average). You will have fewer flight options on Tuesday, which is when the least amount of flights are scheduled (10 on average).

How much does it cost to fly round-trip from Biloxi to Chicago?

Reviews of airlines servicing Chicago

Get insights into the airlines that provide service to Chicago. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Chicago. Reviews last updated septiembre 15, 2025.
Read through reviews of airlines operating flights from Biloxi to Chicago, such as Delta and American Airlines. You can also see how each airline stacks up in terms of entertainment options, comfort, food, crew/service, and boarding process.
Delta
8.0
Very good
7,954 reviews

Entertainment

7.9

Overall

8.0

Comfort

7.9

Boarding

8.2

Crew

8.5

Food

7.3

Reviews

1 / 20
10.0
Excellent

Kim,May 2025

PIH - SLC

This trip was fine even with delay I had plenty of time to get connection flight!
Delta
8.0
Very good
7,954 reviews
Delta
8.0
Very good
7,954 reviews

Entertainment

7.9

Overall

8.0

Comfort

7.9

Boarding

8.2

Crew

8.5

Food

7.3

Reviews

1 / 20
10.0
Excellent

Kim,May 2025

PIH - SLC

This trip was fine even with delay I had plenty of time to get connection flight!
American Airlines
7.2
Good
10,000 reviews
Delta
8.0
Very good
7,954 reviews

Entertainment

7.9

Overall

8.0

Comfort

7.9

Boarding

8.2

Crew

8.5

Food

7.3

Reviews

1 / 20
10.0
Excellent

Kim,May 2025

PIH - SLC

This trip was fine even with delay I had plenty of time to get connection flight!

Related info for your journey

Find useful and relevant information for your journey from Biloxi to Chicago. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • How long is the flight from Biloxi to Chicago?

    Airlines like Delta fly from Biloxi to Chicago in about 6h 23m. The time it takes to get you to your destination can typically vary by up to . Biloxi and Chicago are separated by a distance of 802 mi.

  • What are the cheapest airlines to fly from Biloxi to Chicago one-way?

    $226 is the cheapest one-way deal found within the past few days, from Delta. You may also be able to find cheap deals on American Airlines and United Airlines, with prices starting from $226 and $261, respectively.

  • What are the most reliable airlines from Biloxi to Chicago?

    Before booking your flight to Chicago from Biloxi, check out the most reliable airlines to get you to your destination on time: Turkish Airlines (92%), Japan Airlines (89%), Envoy Air( 88%).

  • What are the cheapest flights from Biloxi to Chicago?

    Looking at all options, your cheapest flight can be booked for $58. While the most popular route (Gulfport Biloxi Regional - Chicago O'Hare Intl) can be booked for $228 on average, our data indicates $851 when flying from Biloxi to Chicago.

  • Can I find deals for flights from Biloxi to Chicago that include hotel bookings?

    Yes. In addition to deals on Biloxi to Chicago flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Biloxi to Chicago?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Biloxi to Chicago.

  • Can I find deals for business class flights from Biloxi to Chicago?

    Yes. Cheapflights offers flight deals from Biloxi to Chicago by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Biloxi to Chicago?

    Currently, August is the cheapest month in which you can book a flight from Biloxi to Chicago (average of $245). Flying from Biloxi to Chicago in March is currently the most expensive (average of $321). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

Traveling to a place near Chicago?

Book flights to Chicago if you plan to visit one of these locations
Merrillville
Lansing
Hammond
Benton Harbor
Porter
Chesterton

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Alternative routes for Biloxi to Chicago

See prices for flight routes from nearby airports that may be better suited for you.
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Top 5 airlines flying from Biloxi to Chicago

Discover the top 5 airlines that operate flights from Biloxi to Chicago. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated septiembre 15, 2025.
AirlineCheapestAverageFlexibilityOn-time
Spirit AirlinesCheapest$63Average$185FlexibilityNo cancel feeOn-time65%
DeltaCheapest$116Average$394FlexibilityNo cancel feeOn-timeN/A
United AirlinesCheapest$137Average$332FlexibilityNo cancel feeOn-time69%
American AirlinesCheapest$151Average$367FlexibilityNo cancel feeOn-time71%
SouthwestCheapest$188Average$287FlexibilityNo cancel feeOn-time63%

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