$209+ Cheap flights from Chicago (CHI) to Biloxi, MS
This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 5/24. Fares are subject to change and may not be available on all flights or dates of travel.
CHI — MSY
Jun 17 — Jun 241
Round-trip
1 adult, Economy
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Find cheap flights from Chicago to Biloxi with Cheapflights
1. Tell us where you want to go
Enter your travel information like dates, passengers, trip type (one-way or round trip), and preferred cabin class then click “Find deals”2. Select your favorite providers
We find the providers serving your travel needs. Choose up to four travel providers to compare side-by-side for flights, hotels, or car rentals.3. Compare prices and book
Review each provider’s pricing and select the best option for you! Book through your favorite provider’s website for a seamless experience.Cheap flight deals from Chicago to Biloxi
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Cheapest flights from Chicago to BiloxiExplore the most affordable flight options available from Chicago to Biloxi. Find the lowest fares from popular airlines and budget airlines, with prices last updated on May 18, 2026.
Explore the most affordable flight options available from Chicago to Biloxi. Find the lowest fares from popular airlines and budget airlines, with prices last updated on May 18, 2026.
This Delta deal was found by Cheapflights users on 5/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 8/265:10 pm
MDW
- GPT
1 stop5h 11m
Delta
Sat 8/294:00 pm
GPT
- MDW
1 stop6h 36m
Delta
Deal found 5/16![Delta logo]()
$291
This American Airlines deal was found by Cheapflights users on 5/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 7/85:00 am
ORD
- GPT
1 stop5h 55m
American Airlines
Sat 7/116:35 pm
GPT
- ORD
1 stop5h 26m
American Airlines
Deal found 5/14![American Airlines logo]()
$291
This Delta deal was found by Cheapflights users on 5/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 8/2612:29 pm
ORD
- GPT
2 stops9h 52m
Delta
Sat 8/294:00 pm
GPT
- ORD
1 stop4h 46m
Delta
Deal found 5/16![Delta logo]()
$296
This Delta deal was found by Cheapflights users on 5/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 7/31:46 pm
ORD
- GPT
1 stop6h 55m
Delta
Mon 7/131:50 pm
GPT
- ORD
1 stop6h 43m
Delta
Deal found 5/14![Delta logo]()
$300
This Delta deal was found by Cheapflights users on 5/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 9/307:10 am
ORD
- GPT
1 stop6h 23m
Delta
Sun 10/410:30 am
GPT
- ORD
2 stops8h 11m
Delta
Deal found 5/15![Delta logo]()
$305
This Delta deal was found by Cheapflights users on 5/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 7/136:35 am
ORD
- GPT
1 stop6h 30m
Delta
Mon 7/206:30 am
GPT
- ORD
1 stop6h 04m
Delta
Deal found 5/15![Delta logo]()
$309
This American Airlines deal was found by Cheapflights users on 5/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 5/296:47 pm
ORD
- GPT
1 stop5h 14m
American Airlines
Wed 6/36:38 pm
GPT
- ORD
1 stop5h 21m
American Airlines
Deal found 5/14![American Airlines logo]()
$315
This American Airlines deal was found by Cheapflights users on 5/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 7/156:47 pm
ORD
- GPT
1 stop5h 09m
American Airlines
Sat 7/186:35 pm
GPT
- ORD
1 stop5h 26m
American Airlines
Deal found 5/16![American Airlines logo]()
$320
This Delta deal was found by Cheapflights users on 5/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/25:55 pm
ORD
- GPT
1 stop4h 11m
Delta
Tue 10/62:15 pm
GPT
- ORD
1 stop4h 17m
Delta
Deal found 5/13![Delta logo]()
$325
This Delta deal was found by Cheapflights users on 5/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 7/136:00 am
MDW
- GPT
1 stop7h 05m
Delta
Mon 7/206:30 am
GPT
- MDW
1 stop5h 26m
Delta
Deal found 5/16![Delta logo]()
$334
This American Airlines deal was found by Cheapflights users on 5/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 7/95:00 am
ORD
- GPT
1 stop5h 55m
American Airlines
Mon 7/136:35 pm
GPT
- ORD
1 stop5h 26m
American Airlines
Deal found 5/17![American Airlines logo]()
$334
This Delta deal was found by Cheapflights users on 5/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 9/311:10 am
ORD
- GPT
1 stop6h 07m
Delta
Mon 9/76:00 pm
GPT
- ORD
1 stop5h 57m
Delta
Deal found 5/13![Delta logo]()
$339
Best flights from Chicago to BiloxiDiscover carefully curated flight deals from Chicago to Biloxi that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated May 18, 2026.
Discover carefully curated flight deals from Chicago to Biloxi that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated May 18, 2026.
This Delta deal was found by Cheapflights users on 5/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 9/307:10 am
ORD
- GPT
1 stop6h 23m
Delta
Sun 10/46:00 pm
GPT
- ORD
1 stop5h 57m
Delta
Deal found 5/15![Delta logo]()
$300
This American Airlines deal was found by Cheapflights users on 5/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 7/136:47 pm
ORD
- GPT
1 stop5h 09m
American Airlines
Mon 7/206:35 pm
GPT
- ORD
1 stop5h 26m
American Airlines
Deal found 5/18![American Airlines logo]()
$399
This Delta deal was found by Cheapflights users on 5/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/25:55 pm
ORD
- GPT
1 stop4h 11m
Delta
Tue 10/62:15 pm
GPT
- ORD
1 stop4h 17m
Delta
Deal found 5/13![Delta logo]()
$325
This Delta deal was found by Cheapflights users on 5/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 9/38:55 am
ORD
- GPT
2 stops8h 22m
Delta
Mon 9/76:00 pm
GPT
- ORD
1 stop5h 57m
Delta
Deal found 5/13![Delta logo]()
$344
This Delta deal was found by Cheapflights users on 5/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/25:25 pm
MDW
- GPT
1 stop4h 41m
Delta
Tue 10/610:30 am
GPT
- MDW
1 stop5h 55m
Delta
Deal found 5/16![Delta logo]()
$365
This American Airlines deal was found by Cheapflights users on 5/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 6/305:10 am
ORD
- GPT
1 stop5h 04m
American Airlines
Thu 7/26:32 pm
GPT
- ORD
1 stop5h 29m
American Airlines
Deal found 5/17![American Airlines logo]()
$484
This Delta deal was found by Cheapflights users on 5/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 7/34:25 pm
MDW
- GPT
1 stop4h 16m
Delta
Mon 7/136:30 am
GPT
- MDW
1 stop5h 26m
Delta
Deal found 5/14![Delta logo]()
$374
This Delta deal was found by Cheapflights users on 5/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 7/136:00 am
MDW
- GPT
1 stop7h 05m
Delta
Mon 7/206:30 am
GPT
- MDW
1 stop5h 26m
Delta
Deal found 5/14![Delta logo]()
$374
This Delta deal was found by Cheapflights users on 5/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 7/311:30 am
ORD
- GPT
2 stops9h 11m
Delta
Mon 7/136:30 am
GPT
- ORD
2 stops10h 29m
Delta
Deal found 5/14![Delta logo]()
$409
This Delta deal was found by Cheapflights users on 5/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 7/1712:41 pm
MDW
- GPT
1 stop4h 34m
Delta
Tue 7/216:00 pm
GPT
- MDW
1 stop4h 15m
Delta
Deal found 5/17![Delta logo]()
$419
This Delta deal was found by Cheapflights users on 5/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 7/1312:27 pm
ORD
- GPT
2 stops9h 47m
Delta
Mon 7/206:30 am
GPT
- ORD
1 stop6h 04m
Delta
Deal found 5/15![Delta logo]()
$433
This Delta deal was found by Cheapflights users on 5/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 6/1111:05 am
MDW
- GPT
1 stop6h 06m
Delta
Mon 6/156:30 am
GPT
- MDW
1 stop5h 35m
Delta
Deal found 5/13![Delta logo]()
$439
This Delta deal was found by Cheapflights users on 5/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 7/163:22 pm
ORD
- GPT
1 stop6h 52m
Delta
Tue 7/216:00 pm
GPT
- ORD
2 stops13h 59m
Delta
Deal found 5/16![Delta logo]()
$467
This Delta deal was found by Cheapflights users on 5/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 6/25:15 pm
MDW
- GPT
1 stop4h 36m
Delta
Sun 6/145:56 pm
GPT
- MDW
1 stop4h 21m
Delta
Deal found 5/15![Delta logo]()
$517
This Delta deal was found by Cheapflights users on 5/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 6/2411:05 am
MDW
- GPT
1 stop6h 06m
Delta
Sun 6/285:57 pm
GPT
- MDW
1 stop4h 20m
Delta
Deal found 5/13![Delta logo]()
$541
This Delta deal was found by Cheapflights users on 5/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 7/166:00 am
MDW
- GPT
1 stop7h 05m
Delta
Sun 7/196:30 am
GPT
- MDW
1 stop5h 26m
Delta
Deal found 5/16![Delta logo]()
$611
Last-minute flights from Chicago to BiloxiDiscover last-minute flight deals from Chicago to Biloxi. Data last updated May 18, 2026 and is based on user searches.
Discover last-minute flight deals from Chicago to Biloxi. Data last updated May 18, 2026 and is based on user searches.
This Delta deal was found by Cheapflights users on 5/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 5/155:10 pm
MDW
- GPT
1 stop4h 41m
Delta
Tue 5/1910:08 am
GPT
- MDW
1 stop6h 04m
Delta
Deal found 5/14![Delta logo]()
$454
This United Airlines deal was found by Cheapflights users on 5/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 5/215:30 am
ORD
- GPT
1 stop7h 55m
United Airlines
Sat 5/235:24 pm
GPT
- ORD
1 stop5h 51m
United Airlines
Deal found 5/17![United Airlines logo]()
$440
This American Airlines deal was found by Cheapflights users on 5/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 5/215:00 am
ORD
- GPT
1 stop5h 52m
American Airlines
Sun 5/245:00 am
GPT
- ORD
1 stop6h 09m
American Airlines
Deal found 5/14![American Airlines logo]()
$444
This American Airlines deal was found by Cheapflights users on 5/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 5/294:45 pm
ORD
- GPT
1 stop7h 16m
American Airlines
Fri 6/56:38 pm
GPT
- ORD
1 stop5h 20m
American Airlines
Deal found 5/13![American Airlines logo]()
$300
This American Airlines deal was found by Cheapflights users on 5/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 5/296:47 pm
ORD
- GPT
1 stop5h 14m
American Airlines
Wed 6/36:38 pm
GPT
- ORD
1 stop5h 21m
American Airlines
Deal found 5/14![American Airlines logo]()
$315
This Delta deal was found by Cheapflights users on 5/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 5/298:42 am
ORD
- GPT
2 stops8h 32m
Delta
Wed 6/36:02 pm
GPT
- ORD
1 stop6h 06m
Delta
Deal found 5/14![Delta logo]()
$363
This Delta deal was found by Cheapflights users on 5/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 5/2912:53 pm
MDW
- GPT
1 stop4h 21m
Delta
Wed 6/31:55 pm
GPT
- MDW
1 stop7h 14m
Delta
Deal found 5/14![Delta logo]()
$435
This Delta deal was found by Cheapflights users on 5/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 6/116:35 am
ORD
- GPT
1 stop6h 32m
Delta
Mon 6/151:53 pm
GPT
- ORD
1 stop6h 39m
Delta
Deal found 5/13![Delta logo]()
$374
This Delta deal was found by Cheapflights users on 5/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 6/1111:05 am
MDW
- GPT
1 stop6h 06m
Delta
Mon 6/156:30 am
GPT
- MDW
1 stop5h 35m
Delta
Deal found 5/13![Delta logo]()
$439
This American Airlines deal was found by Cheapflights users on 5/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 6/205:29 pm
ORD
- GPT
1 stop6h 30m
American Airlines
Mon 6/226:38 pm
GPT
- ORD
1 stop5h 20m
American Airlines
Deal found 5/15![American Airlines logo]()
$390
This Kiwi.com deal was found by Cheapflights users on 5/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 6/244:59 pm
ORD
- GPT
1 stop26h 11m
Multiple Airlines
Sun 6/287:50 pm
GPT
- ORD
2 stops20h 03m
Multiple Airlines
Deal found 5/13![Multiple Airlines logo]()
$382
This United Airlines deal was found by Cheapflights users on 5/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 6/256:30 am
ORD
- GPT
1 stop6h 55m
United Airlines
Mon 6/295:19 pm
GPT
- ORD
1 stop7h 26m
United Airlines
Deal found 5/13![United Airlines logo]()
$473
One-way flights from Chicago to BiloxiSearch for one-way flight options from Chicago to Biloxi. Find affordable one-way fares based on user searches. Data last updated May 18, 2026.
Search for one-way flight options from Chicago to Biloxi. Find affordable one-way fares based on user searches. Data last updated May 18, 2026.
This Delta deal was found by Cheapflights users on 5/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 5/247:05 am
ORD
- GPT
1 stop6h 59m
Delta
Deal found 5/17![Delta logo]()
$209
This Kiwi.com deal was found by Cheapflights users on 5/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 6/57:29 am
ORD
- GPT
3 stops59h 41m
Multiple Airlines
Deal found 5/15![Multiple Airlines logo]()
$220
This Delta deal was found by Cheapflights users on 5/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 5/244:30 pm
MDW
- GPT
1 stop5h 21m
Delta
Deal found 5/17![Delta logo]()
$230
This Delta deal was found by Cheapflights users on 5/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 8/45:10 pm
MDW
- GPT
1 stop5h 11m
Delta
Deal found 5/14![Delta logo]()
$238
This United Airlines deal was found by Cheapflights users on 5/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 8/48:51 am
ORD
- GPT
1 stop7h 20m
United Airlines
Deal found 5/14![United Airlines logo]()
$238
This Delta deal was found by Cheapflights users on 5/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 8/46:00 am
ORD
- GPT
2 stops11h 15m
Delta
Deal found 5/14![Delta logo]()
$243
This American Airlines deal was found by Cheapflights users on 5/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 6/55:34 pm
ORD
- GPT
1 stop6h 25m
American Airlines
Deal found 5/15![American Airlines logo]()
$269
This Kiwi.com deal was found by Cheapflights users on 5/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 5/231:50 pm
ORD
- GPT
2 stops29h 20m
Multiple Airlines
Deal found 5/16![Multiple Airlines logo]()
$317
This Kiwi.com deal was found by Cheapflights users on 5/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 5/246:00 am
MDW
- GPT
3 stops25h 41m
Multiple Airlines
Deal found 5/17![Multiple Airlines logo]()
$400
This Delta deal was found by Cheapflights users on 5/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 5/237:05 am
ORD
- GPT
1 stop6h 59m
Delta
Deal found 5/15![Delta logo]()
$418
This United Airlines deal was found by Cheapflights users on 5/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 6/59:30 pm
ORD
- GPT
2 stops24h 15m
United Airlines
Deal found 5/15![United Airlines logo]()
$510
Find flight deals from Chicago to Biloxi
Keep the following information in mind while searching for Chicago to Biloxi flight deals. Data was last updated May 18, 2026.
Most accurate provider | FlightHub 3 stars |
|---|---|
Most trusted provider | FlightHub 3 stars |
Round-trip from | $291 (Delta) |
One-way from | $209 (Delta) |
Popular in | April |
Cheapest in | August |
Average price | $411 |
Cheapflights Fare Finder
Customize your flight search to find flights from Chicago to Biloxi that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated May 18, 2026.
Use the filters below to find and compare flights from Chicago to Biloxi that are best for you.
Fly from
Fly to
Route
Depart
Return
Cheapest round-trip
ChicagoGulfport
ORD - GPT
ORDGPT
Chicago O'Hare Intl
Wed 9/30
7:10 am-1:33 pm
1 stop6h 23m
Gulfport Biloxi Regional
Sun 10/4
6:00 pm-11:57 pm
1 stop5h 57m
$300
Quickest round-trip
ChicagoGulfport
ORD - GPT
ORDGPT
Chicago O'Hare Intl
Fri 10/2
5:55 pm-10:06 pm
1 stop4h 11m
Gulfport Biloxi Regional
Tue 10/6
2:15 pm-6:32 pm
1 stop4h 17m
$325
ChicagoGulfport
ORD - GPT
ORDGPT
Chicago O'Hare Intl
Thu 9/3
8:55 am-5:17 pm
2 stops8h 22m
Gulfport Biloxi Regional
Mon 9/7
6:00 pm-11:57 pm
1 stop5h 57m
$344
ChicagoGulfport
MDW - GPT
MDWGPT
Chicago Midway
Fri 10/2
5:25 pm-10:06 pm
1 stop4h 41m
Gulfport Biloxi Regional
Tue 10/6
10:30 am-4:25 pm
1 stop5h 55m
$365
ChicagoGulfport
MDW - GPT
MDWGPT
Chicago Midway
Fri 7/3
4:25 pm-8:41 pm
1 stop4h 16m
Gulfport Biloxi Regional
Mon 7/13
6:30 am-11:56 am
1 stop5h 26m
$374
ChicagoGulfport
MDW - GPT
MDWGPT
Chicago Midway
Mon 7/13
6:00 am-1:05 pm
1 stop7h 05m
Gulfport Biloxi Regional
Mon 7/20
6:30 am-11:56 am
1 stop5h 26m
$374
ChicagoGulfport
ORD - GPT
ORDGPT
Chicago O'Hare Intl
Mon 7/13
6:47 pm-11:56 pm
1 stop5h 09m
Gulfport Biloxi Regional
Mon 7/20
6:35 pm-12:01 am
1 stop5h 26m
$399
ChicagoGulfport
ORD - GPT
ORDGPT
Chicago O'Hare Intl
Fri 7/3
11:30 am-8:41 pm
2 stops9h 11m
Gulfport Biloxi Regional
Mon 7/13
6:30 am-4:59 pm
2 stops10h 29m
$409
ChicagoGulfport
MDW - GPT
MDWGPT
Chicago Midway
Fri 7/17
12:41 pm-5:15 pm
1 stop4h 34m
Gulfport Biloxi Regional
Tue 7/21
6:00 pm-10:15 pm
1 stop4h 15m
$419
ChicagoGulfport
ORD - GPT
ORDGPT
Chicago O'Hare Intl
Mon 7/13
12:27 pm-10:14 pm
2 stops9h 47m
Gulfport Biloxi Regional
Mon 7/20
6:30 am-12:34 pm
1 stop6h 04m
$433
Showing 1-10 of 26 resultsSorted by cheapest first
Best time to book a flight from Chicago to Biloxi
Have a flexible travel schedule? Discover the best time to fly to Biloxi from Chicago with our price prediction graph.
MDW-GPT
ORD-GPT
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.
Cheapflights Insights
Everything you need to know about your flight from Chicago to Biloxi
CHI-B1L
MDW-GPT
ORD-GPT
What is the cheapest time of day to fly from CHI to B1L?
Find hourly flight availability from Chicago to Biloxi. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated May 18, 2026.
One of the essential ways to save on airfare from Chicago to Biloxi is to remain as flexible as possible. Flights that are in the afternoon tend to be the most expensive. A flight in the evening could potentially save you up to 15% on airfare.
What is the cheapest day to fly from Chicago to Biloxi?
Use this chart to determine the cheapest time to fly round-trip from Chicago to Biloxi. Price data was last updated on May 16, 2026.
Travelers seeking maximum savings on their Chicago to Biloxi flight should consider departing on Saturday evenings when fares are most often at their lowest. Thursday afternoons flights should be avoided if possible as fares are typically the most expensive at this time.
Weekly flight availability from Chicago to Biloxi
Explore weekly flight availability from Chicago to Biloxi. Discover flights operating on different days of the week, giving you the flexibility to choose a travel day that best fits your plans. Compare info to find the most convenient option for your journey. Data last updated May 18, 2026.
The most flights from CHI to B1L are scheduled on a Sunday (39 on average). You will have fewer flight options on Thursday, which is when the least amount of flights are scheduled (3 on average).
How much does it cost to fly round-trip from Chicago to Biloxi?
Reviews of airlines servicing Biloxi
Get insights into the airlines that provide service to Biloxi. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Biloxi. Reviews last updated May 18, 2026.
Read through reviews of airlines operating flights from Chicago to Biloxi, such as Delta and American Airlines. Reviews also offer insight into each airline's entertainment options, comfort, food, crew/service, and boarding process.
Food
7.2
Overall
7.9
Boarding
8.1
Comfort
7.8
Crew
8.5
Entertainment
7.8
Reviews
1 / 20
10.0
ExcellentAnonymous,May 2026
SEA - KOA
Food
7.2
Overall
7.9
Boarding
8.1
Comfort
7.8
Crew
8.5
Entertainment
7.8
Reviews
1 / 20
10.0
ExcellentAnonymous,May 2026
SEA - KOA
Food
7.2
Overall
7.9
Boarding
8.1
Comfort
7.8
Crew
8.5
Entertainment
7.8
Reviews
1 / 20
10.0
ExcellentAnonymous,May 2026
SEA - KOA
Related info for your journey
Find useful and relevant information for your journey from Chicago to Biloxi. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.
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Alternative routes for Chicago to Biloxi
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Complete your trip
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Chicago and Biloxi flights
Browse other Chicago and Biloxi flight options. Last updated on May 18, 2026.
Other flights from Chicago
Browse through other flights departing from Chicago. Flights are based on user searches made on Cheapflights and were last updated on May 18, 2026.
Popular flight searches
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Chicago to Biloxi flights
Consider these flights traveling from Chicago to Biloxi.
Top 6 airlines flying from Chicago to Biloxi
Discover the top 6 airlines that operate flights from Chicago to Biloxi. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated May 18, 2026.
| Airline | Cheapest | Average | Flexibility | On-time |
|---|---|---|---|---|
| Cheapest$69 | Average$187 | FlexibilityNo cancel fee | On-time65% | |
| Cheapest$98 | Average$227 | FlexibilityNo cancel fee | On-time62% | |
| Cheapest$98 | Average$396 | FlexibilityNo cancel fee | On-timeN/A | |
| Cheapest$163 | Average$353 | FlexibilityNo cancel fee | On-time69% | |
| Cheapest$169 | Average$356 | FlexibilityNo cancel fee | On-time71% | |
| Cheapest$173 | Average$402 | FlexibilityNo cancel fee | On-time63% |