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$286+ Cheap flights from Italy to Charleston (CHS)

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 5/7. Fares are subject to change and may not be available on all flights or dates of travel.
NAP — CHS
Feb 20 — Feb 271
Fri 2/20
Fri 2/27
1 adult, Economy
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Cheap flight deals from Italy to Charleston

Cheapest flights from Italy to Charleston
Explore the most affordable flight options available from Italy to Charleston. Find the lowest fares from popular airlines and budget airlines, with prices last updated on January 21, 2026.

This American Airlines deal was found by Cheapflights users on 1/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 1/2910:25 am
MXP
-
CHS
1 stop16h 47m
American Airlines
Mon 2/210:18 am
CHS
-
MXP
2 stops15h 47m
American Airlines
Deal found 1/20$654
This American Airlines deal was found by Cheapflights users on 1/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 1/2911:25 am
LIN
-
CHS
2 stops16h 18m
American Airlines
Mon 2/25:41 pm
CHS
-
LIN
2 stops14h 49m
American Airlines
Deal found 1/21$661
This American Airlines deal was found by Cheapflights users on 1/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 2/67:30 am
FCO
-
CHS
2 stops17h 18m
American Airlines
Mon 2/92:37 pm
CHS
-
FCO
2 stops22h 58m
American Airlines
Deal found 1/19$668
This American Airlines deal was found by Cheapflights users on 1/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 1/296:20 am
NAP
-
CHS
2 stops21h 23m
American Airlines
Mon 2/27:20 pm
CHS
-
NAP
2 stops36h 50m
American Airlines
Deal found 1/18$676
This United Airlines deal was found by Cheapflights users on 1/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 2/192:50 pm
LIN
-
CHS
2 stops25h 19m
United Airlines
Mon 2/232:48 pm
CHS
-
LIN
2 stops17h 17m
United Airlines
Deal found 1/19$678
This United Airlines deal was found by Cheapflights users on 1/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 2/59:45 am
MXP
-
CHS
1 stop14h 14m
United Airlines
Mon 2/96:05 am
CHS
-
MXP
2 stops19h 25m
United Airlines
Deal found 1/19$682
This United Airlines deal was found by Cheapflights users on 1/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 1/299:45 am
MXP
-
CHS
2 stops15h 19m
United Airlines
Mon 2/211:00 am
CHS
-
MXP
2 stops16h 55m
United Airlines
Deal found 1/20$685
This Gotogate deal was found by Cheapflights users on 1/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Gotogate is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 1/291:05 pm
MXP
-
CHS
2 stops31h 43m
Air Canada
Mon 2/26:00 am
CHS
-
MXP
3 stops21h 55m
Air Canada
Deal found 1/20$693
This United Airlines deal was found by Cheapflights users on 1/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 2/67:00 am
FCO
-
CHS
2 stops22h 48m
United Airlines
Mon 2/97:45 pm
CHS
-
FCO
1 stop30h 45m
United Airlines
Deal found 1/19$694
This British Airways deal was found by Cheapflights users on 1/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure British Airways is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 1/297:15 am
LIN
-
CHS
2 stops21h 19m
British Airways
Mon 2/27:20 pm
CHS
-
LIN
2 stops18h 20m
British Airways
Deal found 1/20$721
This Air Canada deal was found by Cheapflights users on 1/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Air Canada is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 1/291:05 pm
MXP
-
CHS
3 stops29h 27m
Multiple Airlines
Mon 2/211:00 am
CHS
-
MXP
2 stops16h 55m
Multiple Airlines
Deal found 1/21$738
This Expedia deal was found by Cheapflights users on 1/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Expedia is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 8/19:00 am
FCO
-
CHS
1 stop14h 58m
KLM
Sat 8/155:55 pm
CHS
-
FCO
1 stop31h 40m
KLM
Deal found 1/21$936

Find flight deals from Italy to Charleston

Keep the following information in mind while searching for Italy to Charleston flight deals. Data was last updated January 21, 2026.

Round-trip from

$654
(American Airlines)

One-way from

$286
(Kiwi.com)
From Italy to Charleston
Search Deals
One-way flight from Italy to Charleston
Search Deals

Cheapflights Fare Finder

 
Customize your flight search to find flights from Italy to Charleston that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated January 21, 2026.
Use the filters below to find and compare flights from Italy to Charleston that are best for you.

Fly from

Italy

Fly to

Charleston

Route

Depart

Return

Price

MilanCharleston

MXP - CHS

MXPCHS

Milan Malpensa

Thu 2/5

10:25 am-9:48 am

2 stops29h 23m

Charleston

Mon 2/9

11:12 am-8:05 am

2 stops14h 53m

$654

RomeCharleston

FCO - CHS

FCOCHS

Rome Fiumicino

Fri 2/6

7:30 am-9:43 pm

2 stops20h 13m

Charleston

Mon 2/9

2:37 pm-7:35 pm

2 stops22h 58m

$672

MilanCharleston

LIN - CHS

LINCHS

Milan Linate

Thu 2/19

2:50 pm-10:09 am

2 stops25h 19m

Charleston

Mon 2/23

2:48 pm-2:05 pm

2 stops17h 17m

$678

MilanCharleston

MXP - CHS

MXPCHS

Milan Malpensa

Thu 2/5

9:45 am-5:59 pm

1 stop14h 14m

Charleston

Mon 2/9

6:05 am-7:30 am

2 stops19h 25m

$682

RomeCharleston

FCO - CHS

FCOCHS

Rome Fiumicino

Fri 2/6

11:00 am-7:04 pm

1 stop14h 04m

Charleston

Mon 2/9

7:45 pm-8:30 am

1 stop30h 45m

$698

RomeCharleston

FCO - CHS

FCOCHS

Rome Fiumicino

Tue 6/30

7:30 am-11:55 pm

2 stops22h 25m

Charleston

Mon 7/13

1:51 pm-10:30 am

2 stops38h 39m

$3,463

RomeCharleston

FCO - CHS

FCOCHS

Rome Fiumicino

Tue 6/30

9:10 pm-7:48 pm

2 stops28h 38m

Charleston

Mon 7/13

10:59 am-7:05 am

1 stop14h 06m

$3,575

RomeCharleston

FCO - CHS

FCOCHS

Rome Fiumicino

Thu 4/9

3:10 pm-4:32 pm

2 stops55h 22m

Charleston

Thu 4/16

5:55 pm-6:25 pm

2 stops42h 30m

$3,632

RomeCharleston

FCO - CHS

FCOCHS

Rome Fiumicino

Thu 4/9

2:15 pm-8:31 am

1 stop24h 16m

Charleston

Sun 4/19

7:13 pm-7:05 am

1 stop29h 52m

$3,849

RomeCharleston

FCO - CHS

FCOCHS

Rome Fiumicino

Mon 4/13

7:05 pm-4:00 pm

1 stop26h 55m

$353

Flights are sorted by cheapest round-trip flights first.

Deals found on 1/20

Showing 1-10 of 32 results
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Best time to book a flight from Italy to Charleston

Have a flexible travel schedule? Discover the best time to fly to Charleston from Italy with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Italy to Charleston
No data available for this route at this time. Please check back soon.

Related info for your journey

Find useful and relevant information for your journey from Italy to Charleston. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • What airport do you fly into for flights to Charleston from Italy?

    Located just 10.2 mi from the city center, Charleston (CHS) is the airport most travelers will use when flying to Charleston from Italy.

  • How long is the flight from Italy to Charleston?

    Airlines like American Airlines and United Airlines fly from Italy to Charleston in about 25h 19m. The time it takes to get you to your destination can typically vary by up to 4h 04m. The distance from Italy to Charleston is about 4612 mi. This flight may include one or multiple stops.

  • What are the most popular routes from Italy to Charleston?

    While some choose either Milan Linate - Charleston or Milan Malpensa - Charleston, Rome Fiumicino - Charleston is the most popular route from Italy to Charleston.

  • Can I find deals for flights from Italy to Charleston that include hotel bookings?

    Yes. In addition to deals on Italy to Charleston flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Italy to Charleston?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Italy to Charleston.

  • Can I find deals for business class flights from Italy to Charleston?

    Yes. Cheapflights offers flight deals from Italy to Charleston by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

See more FAQs

Traveling to a place near Charleston?

Book flights to Charleston if you plan to visit one of these locations
North Charleston
Santee
Summerville
Walterboro
Isle of Palms
Mount Pleasant
Edisto Beach

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